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Laurence Zitvogel
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Anatomy
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42
Kroemer, Guido
38
Chaput, Nathalie
26
Ghiringhelli, François
24
Tesniere, Antoine
22
Apetoh, Lionel
21
Flament, Caroline
20
Angevin, Eric
17
Tursz, Thomas
16
Terme, Magali
15
Ullrich, Evelyn
14
Panaretakis, Theocharis
14
Mignot, Grégoire
13
André, Fabrice
12
Amigorena, Sebastian
11
Taieb, Julien
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All Publications
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2009: Martins Isabelle; Tesniere Antoine; Kepp Oliver; Michaud Mickael; Schlemmer Frederic; Senovilla Laura; Séror Claire; Métivier Didier; Perfettini Jean-Luc; Zitvogel Laurence; Kroemer Guido
Chemotherapy induces ATP release from tumor cells.
Cell cycle (Georgetown, Tex.) 2009;8(22):3723-8.
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2009: Ghiringhelli François; Apetoh Lionel; Tesniere Antoine; Aymeric Laetitia; Ma Yuting; Ortiz Carla; Vermaelen Karim; Panaretakis Theocharis; Mignot Grégoire; Ullrich Evelyn; Perfettini Jean-Luc; Schlemmer Frédéric; Tasdemir Ezgi; Uhl Martin; Génin Pierre; Civas Ahmet; Ryffel Bernhard; Kanellopoulos Jean; Tschopp Jürg; André Fabrice; Lidereau Rosette; McLaughlin Nicole M; Haynes Nicole M; Smyth Mark J; Kroemer Guido; Zitvogel Laurence
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
Nature medicine 2009;15(10):1170-8.
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2009: Locher Clara; Rusakiewicz Sylvie; Tesnière Antoine; Ghiringhelli François; Apetoh Lionel; Kroemer Guido; Zitvogel Laurence
Witch hunt against tumor cells enhanced by dendritic cells.
Annals of the New York Academy of Sciences 2009;1174():51-60.
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2009: Terme Magali; Mignot Grégoire; Ullrich Evelyn; Bonmort Mathieu; Minard-Colin Véronique; Jacquet Alexandra; Schultze Joachim L; Kroemer Guido; Leclerc Claude; Chaput Nathalie; Zitvogel Laurence
The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells.
Cancer research 2009;69(16):6590-7.
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2009: Zitvogel Laurence; Kroemer Guido
Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects.
The Journal of clinical investigation 2009;119(8):2127-30.
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2009: Green Douglas R; Ferguson Thomas; Zitvogel Laurence; Kroemer Guido
Immunogenic and tolerogenic cell death.
Nature reviews. Immunology 2009;9(5):353-63.
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2009: Ménard Cédric; Blay Jean-Yves; Borg Christophe; Michiels Stefan; Ghiringhelli François; Robert Caroline; Nonn Céline; Chaput Nathalie; Taïeb Julien; Delahaye Nicolas F; Flament Caroline; Emile Jean-François; Le Cesne Axel; Zitvogel Laurence
Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients.
Cancer research 2009;69(8):3563-9.
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2009: Kepp Oliver; Tesniere Antoine; Schlemmer Frederic; Michaud Mickael; Senovilla Laura; Zitvogel Laurence; Kroemer Guido
Immunogenic cell death modalities and their impact on cancer treatment.
Apoptosis : an international journal on programmed cell death 2009;14(4):364-75.
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2009: Kepp Oliver; Senovilla Laura; Galluzzi Lorenzo; Panaretakis Theocharis; Tesniere Antoine; Schlemmer Frederic; Madeo Frank; Zitvogel Laurence; Kroemer Guido
Viral subversion of immunogenic cell death.
Cell cycle (Georgetown, Tex.) 2009;8(6):860-9.
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2009: Panaretakis Theocharis; Kepp Oliver; Brockmeier Ulf; Tesniere Antoine; Bjorklund Ann-Charlotte; Chapman Daniel C; Durchschlag Michael; Joza Nicholas; Pierron Gérard; van Endert Peter; Yuan Junying; Zitvogel Laurence; Madeo Frank; Williams David B; Kroemer Guido
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death.
The EMBO journal 2009;28(5):578-90.
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2009: Madeo Frank; Durchschlag Michael; Kepp Oliver; Panaretakis Theocharis; Zitvogel Laurence; Fröhlich Kai-Uwe; Kroemer Guido
Phylogenetic conservation of the preapoptotic calreticulin exposure pathway from yeast to mammals.
Cell cycle (Georgetown, Tex.) 2009;8(4):639-42.
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2009: Kepp Oliver; Tesniere Antoine; Zitvogel Laurence; Kroemer Guido
The immunogenicity of tumor cell death.
Current opinion in oncology 2009;21(1):71-6.
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2009: Viaud Sophie; Terme Magali; Flament Caroline; Taieb Julien; André Fabrice; Novault Sophie; Escudier Bernard; Robert Caroline; Caillat-Zucman Sophie; Tursz Thomas; Zitvogel Laurence; Chaput Nathalie
Dendritic cell-derived exosomes promote natural killer cell activation and proliferation: a role for NKG2D ligands and IL-15Ralpha.
PloS one 2009;4(3):e4942.
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2008: Zitvogel Laurence; Kroemer Guido
The dilemma of anticancer therapy: tumor-specific versus immune effects.
Blood 2008;112(12):4364-5.
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2008: Pallandre Jean R; Krzewski Konrad; Bedel Romain; Ryffel Bernhard; Caignard Anne; Rohrlich Pierre Simon; Pivot Xavier; Tiberghien Pierre; Zitvogel Laurence; Strominger Jack L; Borg Christophe
Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activation.
Blood 2008;112(12):4420-4.
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2008: Roux Stephan; Apetoh Lionel; Chalmin Fanny; Ladoire Sylvain; Mignot Grégoire; Puig Pierre-Emmanuel; Lauvau Gregoire; Zitvogel Laurence; Martin François; Chauffert Bruno; Yagita Hideo; Solary Eric; Ghiringhelli François
CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer.
The Journal of clinical investigation 2008;118(11):3751-61.
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2008: Zitvogel Laurence; Tesniere Antoine; Apetoh Lionel; Ghiringhelli François; Kroemer Guido
[Immunological aspects of anticancer chemotherapy]
Bulletin de l'Académie nationale de médecine 2008;192(7):1469-87; discussion 1487-9.
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2008: Chaput N; Conforti R; Viaud S; Spatz A; Zitvogel L
The Janus face of dendritic cells in cancer.
Oncogene 2008;27(45):5920-31.
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2008: Zitvogel Laurence; Kroemer Guido
Introduction: the immune response against dying cells.
Current opinion in immunology 2008;20(5):501-3.
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2008: Tesniere Antoine; Apetoh Lionel; Ghiringhelli Francois; Joza Nicholas; Panaretakis Theocharis; Kepp Oliver; Schlemmer Frederic; Zitvogel Laurence; Kroemer Guido
Immunogenic cancer cell death: a key-lock paradigm.
Current opinion in immunology 2008;20(5):504-11.
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2008: Bonmort Mathieu; Dalod Marc; Mignot Grégoire; Ullrich Evelyn; Chaput Nathalie; Zitvogel Laurence
Killer dendritic cells: IKDC and the others.
Current opinion in immunology 2008;20(5):558-65.
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2008: Panaretakis T; Joza N; Modjtahedi N; Tesniere A; Vitale I; Durchschlag M; Fimia G M; Kepp O; Piacentini M; Froehlich K-U; van Endert P; Zitvogel L; Madeo F; Kroemer G
The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death.
Cell death and differentiation 2008;15(9):1499-509.
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2008: Roux Stephan; Bernat Claire; Al-Sakere Bassim; Ghiringhelli François; Opolon Paule; Carpentier Antoine F; Zitvogel Laurence; Mir Lluis M; Robert Caroline
Tumor destruction using electrochemotherapy followed by CpG oligodeoxynucleotide injection induces distant tumor responses.
Cancer immunology, immunotherapy : CII 2008;57(9):1291-300.
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2008: Ménard Cédric; Ghiringhelli François; Roux Stephan; Chaput Nathalie; Mateus Christine; Grohmann Ursula; Caillat-Zucman Sophie; Zitvogel Laurence; Robert Caroline
Ctla-4 blockade confers lymphocyte resistance to regulatory T-cells in advanced melanoma: surrogate marker of efficacy of tremelimumab?
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(16):5242-9.
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2008: Zitvogel Laurence; Apetoh Lionel; Ghiringhelli François; André Fabrice; Tesniere Antoine; Kroemer Guido
The anticancer immune response: indispensable for therapeutic success?
The Journal of clinical investigation 2008;118(6):1991-2001.
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2008: Ullrich Evelyn; Bonmort Mathieu; Mignot Gregoire; Jacobs Benedikt; Bosisio Daniela; Sozzani Silvano; Jalil Abdelali; Louache Fawzia; Bulanova Elena; Geissman Frederic; Ryffel Bernard; Chaput Nathalie; Bulfone-Paus Silvia; Zitvogel Laurence
Trans-presentation of IL-15 dictates IFN-producing killer dendritic cells effector functions.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):7887-97.
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2008: Apetoh Lionel; Tesniere Antoine; Ghiringhelli François; Kroemer Guido; Zitvogel Laurence
Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies.
Cancer research 2008;68(11):4026-30.
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2008: Zitvogel Laurence; Mignot Grégoire; Bonmort Mathieu; Ullrich Evelyn; Chaput Nathalie
[IKDC: killer dendritic cells or antigen-presenting NK cells?]
Médecine sciences : M/S 2008;24(5):525-8.
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2008: Mignot Grégoire; Ullrich Evelyn; Bonmort Mathieu; Ménard Cédric; Apetoh Lionel; Taieb Julien; Bosisio Daniela; Sozzani Silvano; Ferrantini Maria; Schmitz Jürg; Mack Matthias; Ryffel Bernard; Bulfone-Paus Silvia; Zitvogel Laurence; Chaput Nathalie
The critical role of IL-15 in the antitumor effects mediated by the combination therapy imatinib and IL-2.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6477-83.
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2008: Terme Magali; Ullrich Evelyn; Delahaye Nicolas F; Chaput Nathalie; Zitvogel Laurence
Natural killer cell-directed therapies: moving from unexpected results to successful strategies.
Nature immunology 2008;9(5):486-94.
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2008: Apetoh L; Ghiringhelli F; Tesniere A; Obeid M; Mignot G; Ullrich E; Kroemer G; Zitvogel L
Cancer is not just a disease of a tissue: it is a host disease. How to reactivate host defense against tumors using conventional therapies of cancer?
Annales d'endocrinologie 2008;69(2):151-2.
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2008: Terme Magali; Chaput Nathalie; Combadiere Behazine; Ma Averil; Ohteki Toshiaki; Zitvogel Laurence
Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4679-86.
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2008: Apetoh Lionel; Mignot Grégoire; Panaretakis Theocharis; Kroemer Guido; Zitvogel Laurence
Immunogenicity of anthracyclines: moving towards more personalized medicine.
Trends in molecular medicine 2008;14(4):141-51.
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2008: Viaud S; Ullrich E; Zitvogel L; Chaput N
Exosomes for the treatment of human malignancies.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(2):82-8.
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2008: Ullrich E; Chaput N; Zitvogel L
Killer dendritic cells and their potential role in immunotherapy.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(2):75-81.
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2008: Ullrich Evelyn; Ménard Cédric; Flament Caroline; Terme Magali; Mignot Grégoire; Bonmort Mathieu; Plumas Jöel; Chaperot Laurence; Chaput Nathalie; Zitvogel Laurence
Dendritic cells and innate defense against tumor cells.
Cytokine & growth factor reviews 2008;19(1):79-92.
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2008: Tufi R; Panaretakis T; Bianchi K; Criollo A; Fazi B; Di Sano F; Tesniere A; Kepp O; Paterlini-Brechot P; Zitvogel L; Piacentini M; Szabadkai G; Kroemer G
Reduction of endoplasmic reticulum Ca2+ levels favors plasma membrane surface exposure of calreticulin.
Cell death and differentiation 2008;15(2):274-82.
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2008: Zitvogel Laurence; Apetoh Lionel; Ghiringhelli François; Kroemer Guido
Immunological aspects of cancer chemotherapy.
Nature reviews. Immunology 2008;8(1):59-73.
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2008: Zitvogel L; Kroemer G
The immune response against dying tumor cells: avoid disaster, achieve cure.
Cell death and differentiation 2008;15(1):1-2.
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2008: Tesniere A; Panaretakis T; Kepp O; Apetoh L; Ghiringhelli F; Zitvogel L; Kroemer G
Molecular characteristics of immunogenic cancer cell death.
Cell death and differentiation 2008;15(1):3-12.
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2008: Ullrich E; Bonmort M; Mignot G; Kroemer G; Zitvogel L
Tumor stress, cell death and the ensuing immune response.
Cell death and differentiation 2008;15(1):21-8.
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2007: Apetoh Lionel; Ghiringhelli François; Tesniere Antoine; Criollo Alfredo; Ortiz Carla; Lidereau Rosette; Mariette Christophe; Chaput Nathalie; Mira Jean-Paul; Delaloge Suzette; André Fabrice; Tursz Thomas; Kroemer Guido; Zitvogel Laurence
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy.
Immunological reviews 2007;220():47-59.
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2007: Obeid Michel; Tesniere Antoine; Panaretakis Theocharis; Tufi Roberta; Joza Nick; van Endert Peter; Ghiringhelli François; Apetoh Lionel; Chaput Nathalie; Flament Caroline; Ullrich Evelyn; de Botton Stéphane; Zitvogel Laurence; Kroemer Guido
Ecto-calreticulin in immunogenic chemotherapy.
Immunological reviews 2007;220():22-34.
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2007: Kroemer Guido; Zitvogel Laurence
Death, danger, and immunity: an infernal trio.
Immunological reviews 2007;220():5-7.
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2007: Chaput Nathalie; De Botton Stéphane; Obeid Michel; Apetoh Lionel; Ghiringhelli François; Panaretakis Theocharis; Flament Caroline; Zitvogel Laurence; Kroemer Guido
Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference.
Journal of molecular medicine (Berlin, Germany) 2007;85(10):1069-76.
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2007: Obeid M; Panaretakis T; Joza N; Tufi R; Tesniere A; van Endert P; Zitvogel L; Kroemer G
Calreticulin exposure is required for the immunogenicity of gamma-irradiation and UVC light-induced apoptosis.
Cell death and differentiation 2007;14(10):1848-50.
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2007: Obeid Michel; Panaretakis Theocharis; Tesniere Antoine; Joza Nick; Tufi Roberta; Apetoh Lionel; Ghiringhelli François; Zitvogel Laurence; Kroemer Guido
Leveraging the immune system during chemotherapy: moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenic.
Cancer research 2007;67(17):7941-4.
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2007: Apetoh Lionel; Ghiringhelli François; Tesniere Antoine; Obeid Michel; Ortiz Carla; Criollo Alfredo; Mignot Grégoire; Maiuri M Chiara; Ullrich Evelyn; Saulnier Patrick; Yang Huan; Amigorena Sebastian; Ryffel Bernard; Barrat Franck J; Saftig Paul; Levi Francis; Lidereau Rosette; Nogues Catherine; Mira Jean-Paul; Chompret Agnès; Joulin Virginie; Clavel-Chapelon Françoise; Bourhis Jean; André Fabrice; Delaloge Suzette; Tursz Thomas; Kroemer Guido; Zitvogel Laurence
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.
Nature medicine 2007;13(9):1050-9.
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2007: Galluzzi L; Maiuri M C; Vitale I; Zischka H; Castedo M; Zitvogel L; Kroemer G
Cell death modalities: classification and pathophysiological implications.
Cell death and differentiation 2007;14(7):1237-43.
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2007: Bonmort Mathieu; Ullrich Evelyn; Mignot Grégoire; Jacobs Bénédikt; Chaput Nathalie; Zitvogel Laurence
Interferon-gamma is produced by another player of innate immune responses: the interferon-producing killer dendritic cell (IKDC).
Biochimie 2007;89(6-7):872-7.
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2007: Ghiringhelli François; Menard Cedric; Puig Pierre Emmanuel; Ladoire Sylvain; Roux Stephan; Martin François; Solary Eric; Le Cesne Axel; Zitvogel Laurence; Chauffert Bruno
Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients.
Cancer immunology, immunotherapy : CII 2007;56(5):641-8.
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2007: Ghiringhelli François; Apetoh Lionel; Housseau Frank; Kroemer Guido; Zitvogel Laurence
Links between innate and cognate tumor immunity.
Current opinion in immunology 2007;19(2):224-31.
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2007: Apetoh Lionel; Obeid Michel; Tesniere Antoine; Ghiringhelli François; Fimia Gian Maria; Piacentini Mauro; Kroemer Guido; Zitvogel Laurence
Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells.
Cancer genomics & proteomics 2007;4(2):65-70.
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2007: Apetoh Lionel; Ghiringhelli François; Zitvogel Laurence
[Calreticulin dictates the immunogenicity of anti-cancer chemotherapy and radiotherapy]
Médecine sciences : M/S 2007;23(3):257-8.
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2007: Ullrich Evelyn; Bonmort Mathieu; Mignot Grégoire; Chaput Nathalie; Taieb Julien; Ménard Cédric; Viaud Sophie; Tursz Thomas; Kroemer Guido; Zitvogel Laurence
Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells.
Cancer research 2007;67(3):851-3.
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2007: Obeid Michel; Tesniere Antoine; Ghiringhelli François; Fimia Gian Maria; Apetoh Lionel; Perfettini Jean-Luc; Castedo Maria; Mignot Grégoire; Panaretakis Theoharis; Casares Noelia; Métivier Didier; Larochette Nathanael; van Endert Peter; Ciccosanti Fabiola; Piacentini Mauro; Zitvogel Laurence; Kroemer Guido
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Nature medicine 2007;13(1):54-61.
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2006: Castedo Maria; Coquelle Arnaud; Vitale Ilio; Vivet Sonia; Mouhamad Shahul; Viaud Sophie; Zitvogel Laurence; Kroemer Guido
Selective resistance of tetraploid cancer cells against DNA damage-induced apoptosis.
Annals of the New York Academy of Sciences 2006;1090():35-49.
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2006: Tesniere Antoine; Zitvogel Laurence; Kroemer Guido
The immune system: taming and unleashing cancer.
Discovery medicine 2006;6(36):211-6.
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2006: Ghiringhelli Francois; Ménard Cédric; Martin Francois; Zitvogel Laurence
The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression.
Immunological reviews 2006;214():229-38.
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2006: Zitvogel Laurence; Tesniere Antoine; Kroemer Guido
Cancer despite immunosurveillance: immunoselection and immunosubversion.
Nature reviews. Immunology 2006;6(10):715-27.
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2006: Chaput Nathalie; Flament Caroline; Viaud Sophie; Taieb Julien; Roux Stephan; Spatz Alain; André Fabrice; LePecq Jean-Bernard; Boussac Muriel; Garin Jérôme; Amigorena Sebastian; Théry Clotilde; Zitvogel Laurence
Dendritic cell derived-exosomes: biology and clinical implementations.
Journal of leukocyte biology 2006;80(3):471-8.
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2006: Chaput Nathalie; Taieb Julien; Ullrich Evelyn; Zitvogel Laurence
[A new dendritic cell implicated in antitumoral immunity]
Médecine sciences : M/S 2006;22(6-7):567-8.
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2006: Castedo Maria; Coquelle Arnaud; Vivet Sonia; Vitale Ilio; Kauffmann Audrey; Dessen Philippe; Pequignot Marie O; Casares Noelia; Valent Alexandre; Mouhamad Shahul; Schmitt Elise; Modjtahedi Nazanine; Vainchenker William; Zitvogel Laurence; Lazar Vladimir; Garrido Carmen; Kroemer Guido
Apoptosis regulation in tetraploid cancer cells.
The EMBO journal 2006;25(11):2584-95.
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2006: Chaput Nathalie; Taieb Julien; Zitvogel Laurence
[Innate defence against tumor cells: the killer cell IKDC]
Bulletin du cancer 2006;93(5):449-51.
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2006: Mignot G; Roux S; Thery Clotilde; Ségura Elodie; Zitvogel L
Prospects for exosomes in immunotherapy of cancer.
Journal of cellular and molecular medicine 2006;10(2):376-88.
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2006: Taieb Julien; Chaput Nathalie; Schartz Noël; Roux Stéphan; Novault Sophie; Ménard Cédric; Ghiringhelli François; Terme Magali; Carpentier Antoine F; Darrasse-Jèze Guillaume; Lemonnier François; Zitvogel Laurence
Chemoimmunotherapy of tumors: cyclophosphamide synergizes with exosome based vaccines.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):2722-9.
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2006: Ghiringhelli François; Zitvogel Laurence
[Vaccine strategies against melanoma]
Médecine sciences : M/S 2006;22(2):183-7.
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2006: Taieb Julien; Chaput Nathalie; Ménard Cédric; Apetoh Lionel; Ullrich Evelyn; Bonmort Mathieu; Péquignot Marie; Casares Noelia; Terme Magali; Flament Caroline; Opolon Paule; Lecluse Yann; Métivier Didier; Tomasello Elena; Vivier Eric; Ghiringhelli François; Martin François; Klatzmann David; Poynard Thierry; Tursz Thomas; Raposo Graça; Yagita Hideo; Ryffel Bernard; Kroemer Guido; Zitvogel Laurence
A novel dendritic cell subset involved in tumor immunosurveillance.
Nature medicine 2006;12(2):214-9.
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2006: Zitvogel L; Terme M; Borg C; Trinchieri G
Dendritic cell-NK cell cross-talk: regulation and physiopathology.
Current topics in microbiology and immunology 2006;298():157-74.
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2005: Casares Noelia; Pequignot Marie O; Tesniere Antoine; Ghiringhelli François; Roux Stéphan; Chaput Nathalie; Schmitt Elise; Hamai Ahmed; Hervas-Stubbs Sandra; Obeid Michel; Coutant Frédéric; Métivier Didier; Pichard Evelyne; Aucouturier Pierre; Pierron Gérard; Garrido Carmen; Zitvogel Laurence; Kroemer Guido
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death.
The Journal of experimental medicine 2005;202(12):1691-701.
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2005: Zitvogel Laurence; Tursz Thomas
In vivo veritas.
Nature biotechnology 2005;23(11):1372-4.
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2005: Ghiringhelli François; Ménard Cédric; Terme Magali; Flament Caroline; Taieb Julien; Chaput Nathalie; Puig Pierre E; Novault Sophie; Escudier Bernard; Vivier Eric; Lecesne Axel; Robert Caroline; Blay Jean-Yves; Bernard Jacky; Caillat-Zucman Sophie; Freitas Antonio; Tursz Thomas; Wagner-Ballon Orianne; Capron Claude; Vainchencker William; Martin François; Zitvogel Laurence
CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner.
The Journal of experimental medicine 2005;202(8):1075-85.
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2005: Ghiringhelli François; Puig Pierre E; Roux Stephan; Parcellier Arnaud; Schmitt Elise; Solary Eric; Kroemer Guido; Martin François; Chauffert Bruno; Zitvogel Laurence
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation.
The Journal of experimental medicine 2005;202(7):919-29.
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2005: Schartz Noël E C; Chaput Nathalie; Taieb Julien; Bonnaventure Pierre; Trébeden-Nègre Hélène; Terme Magali; Ménard Cédric; Lebbé Céleste; Schimpl Anneliese; Ardouin Patrice; Zitvogel Laurence
IL-2 production by dendritic cells is not critical for the activation of cognate and innate effectors in draining lymph nodes.
European journal of immunology 2005;35(10):2840-50.
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2005: Walzer Thierry; Dalod Marc; Robbins Scott H; Zitvogel Laurence; Vivier Eric
Natural-killer cells and dendritic cells: "l'union fait la force".
Blood 2005;106(7):2252-8.
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2005: Walzer Thierry; Dalod Marc; Vivier Eric; Zitvogel Laurence
Natural killer cell-dendritic cell crosstalk in the initiation of immune responses.
Expert opinion on biological therapy 2005;5 Suppl 1():S49-59.
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2005: Chaput Nathalie; Taïeb Julien; Schartz Noël; Flament Caroline; Novault Sophie; André Fabrice; Zitvogel Laurence
The potential of exosomes in immunotherapy of cancer.
Blood cells, molecules & diseases 2005;35(2):111-5.
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2005: Terme Magali; Borg Christophe; Guilhot François; Masurier Carole; Flament Caroline; Wagner Erwin F; Caillat-Zucman Sophie; Bernheim Alain; Turhan Ali G; Caignard Anne; Zitvogel Laurence
BCR/ABL promotes dendritic cell-mediated natural killer cell activation.
Cancer research 2005;65(14):6409-17.
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2005: Chaput Nathalie; Taïeb Julien; André Fabrice; Zitvogel Laurence
The potential of exosomes in immunotherapy.
Expert opinion on biological therapy 2005;5(6):737-47.
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2005: Taïeb Julien; Chaput Nathalie; Zitvogel Laurence
Dendritic cell-derived exosomes as cell-free peptide-based vaccines.
Critical reviews in immunology 2005;25(3):215-23.
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2004: Borg Christophe; Jalil Abdelali; Laderach Diego; Maruyama Kouji; Wakasugi Hiro; Charrier Sabine; Ryffel Bernhard; Cambi Alessandra; Figdor Carl; Vainchenker William; Galy Anne; Caignard Anne; Zitvogel Laurence
NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.
Blood 2004;104(10):3267-75.
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2004: Borg Christophe; Terme Magali; Taïeb Julien; Ménard Cédric; Flament Caroline; Robert Caroline; Maruyama Koji; Wakasugi Hiro; Angevin Eric; Thielemans Kris; Le Cesne Axel; Chung-Scott Véronique; Lazar Vladimir; Tchou Isabelle; Crépineau Florent; Lemoine François; Bernard Jacky; Fletcher Jonhantan A; Turhan Ali; Blay Jean-Yves; Spatz Alain; Emile Jean-François; Heinrich Michael C; Mécheri Salah; Tursz Thomas; Zitvogel Laurence
Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects.
The Journal of clinical investigation 2004;114(3):379-88.
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2004: Terme Magali; Tomasello Elena; Maruyama Koji; Crépineau Florent; Chaput Nathalie; Flament Caroline; Marolleau Jean-Pierre; Angevin Eric; Wagner Erwin F; Salomon Benoît; Lemonnier François A; Wakasugi Hiro; Colonna Marco; Vivier Eric; Zitvogel Laurence
IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):5957-66.
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2004: Hegmans Joost P J J; Bard Martin P L; Hemmes Annabrita; Luider Theo M; Kleijmeer Monique J; Prins Jan-Bas; Zitvogel Laurence; Burgers Sjaak A; Hoogsteden Henk C; Lambrecht Bart N
Proteomic analysis of exosomes secreted by human mesothelioma cells.
The American journal of pathology 2004;164(5):1807-15.
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2004: Movassagh Mojgan; Spatz Alain; Davoust Jean; Lebecque Serge; Romero Pedro; Pittet Mikaël; Rimoldi Donata; Liénard Danièle; Gugerli Oliver; Ferradini Laurent; Robert Caroline; Avril Marie-Françoise; Zitvogel Laurence; Angevin Eric
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Cancer research 2004;64(6):2192-8.
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2004: Taïeb Julien; Maruyama Koji; Borg Christophe; Terme Magali; Zitvogel Laurence
Imatinib mesylate impairs Flt3L-mediated dendritic cell expansion and antitumor effects in vivo.
Blood 2004;103(5):1966-7; author reply 1967.
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2004: Chaput Nathalie; Taïeb Julien; Schartz Noël E C; André Fabrice; Angevin Eric; Zitvogel Laurence
Exosome-based immunotherapy.
Cancer immunology, immunotherapy : CII 2004;53(3):234-9.
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2004: Chaput Nathalie; Schartz Nöel E C; André Fabrice; Taïeb Julien; Novault Sophie; Bonnaventure Pierre; Aubert Nathalie; Bernard Jacky; Lemonnier François; Merad Miriam; Adema Gosse; Adams Malcolm; Ferrantini Maria; Carpentier Antoine F; Escudier Bernard; Tursz Thomas; Angevin Eric; Zitvogel Laurence
Exosomes as potent cell-free peptide-based vaccine. II. Exosomes in CpG adjuvants efficiently prime naive Tc1 lymphocytes leading to tumor rejection.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2137-46.
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2004: André Fabrice; Chaput Nathalie; Schartz Nöel E C; Flament Caroline; Aubert Nathalie; Bernard Jacky; Lemonnier François; Raposo Graça; Escudier Bernard; Hsu Di-Hwei; Tursz Thomas; Amigorena Sebastian; Angevin Eric; Zitvogel Laurence
Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2126-36.
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2004: Andre F; Escudier B; Angevin E; Tursz T; Zitvogel L
Exosomes for cancer immunotherapy.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15 Suppl 4():iv141-4.
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2004: Zitvogel Laurence; Casares Noelia; Péquignot Marie O; Chaput Nathalie; Albert Matthew L; Kroemer Guido
Immune response against dying tumor cells.
Advances in immunology 2004;84():131-79.
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2003: Hsu Di-Hwei; Paz Pedro; Villaflor Gilbert; Rivas Alberto; Mehta-Damani Anita; Angevin Eric; Zitvogel Laurence; Le Pecq Jean-Bernard
Exosomes as a tumor vaccine: enhancing potency through direct loading of antigenic peptides.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2003;26(5):440-50.
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2003: Borg Christophe; Taieb Julien; Terme Magali; Maruyama Kuji; Flament Caroline; Angevin Eric; Zitvogel Laurence
[NK cell-based immunotherapy: new prospects and involvement of dendritic cells]
Bulletin du cancer 2003;90(8-9):699-705.
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2003: Chaput Nathalie; Andre Fabrice; Schartz Noël E C; Flament Caroline; Angevin Eric; Escudier Bernard; Zitvogel Laurence
[Exosomes and anti-tumour immunotherapy]
Bulletin du cancer 2003;90(8-9):695-8.
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2003: Chaput Nathalie; Schartz N E C; Andre Fabrice; Zitvogel Laurence
Exosomes for immunotherapy of cancer.
Advances in experimental medicine and biology 2003;532():215-21.
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2002: André F; Schartz N E C; Chaput N; Flament C; Raposo G; Amigorena S; Angevin E; Zitvogel L
Tumor-derived exosomes: a new source of tumor rejection antigens.
Vaccine 2002;20 Suppl 4():A28-31.
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2002: Valteau-Couanet Dominique; Leboulaire Christophe; Maincent Kim; Tournier Muriel; Hartmann Olivier; Bénard Jean; Beaujean Françoise; Boccaccio Catherine; Zitvogel Laurence; Angevin Eric
Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients.
Blood 2002;100(7):2554-61.
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2002: Schartz Noël Emile Célestin; Chaput Nathalie; André Fabrice; Zitvogel Laurence
From the antigen-presenting cell to the antigen-presenting vesicle: the exosomes.
Current opinion in molecular therapeutics 2002;4(4):372-81.
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2002: Théry Clotilde; Zitvogel Laurence; Amigorena Sebastian
Exosomes: composition, biogenesis and function.
Nature reviews. Immunology 2002;2(8):569-79.
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2002: Andre Fabrice; Schartz Noel E C; Movassagh Mojgan; Flament Caroline; Pautier Patricia; Morice Philippe; Pomel Christophe; Lhomme Catherine; Escudier Bernard; Le Chevalier Thierry; Tursz Thomas; Amigorena Sebastian; Raposo Graca; Angevin Eric; Zitvogel Laurence
Malignant effusions and immunogenic tumour-derived exosomes.
Lancet 2002;360(9329):295-305.
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2002: Zitvogel Laurence
Dendritic and natural killer cells cooperate in the control/switch of innate immunity.
The Journal of experimental medicine 2002;195(3):F9-14.
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2002: Fernandez Nadine C; Flament Caroline; Crépineau Florent; Angevin Eric; Vivier Eric; Zitvogel Laurence
Dendritic cells (DC) promote natural killer (NK) cell functions: dynamics of the human DC/NK cell cross talk.
European cytokine network 2002;13(1):17-27.
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2002: Guermonprez Pierre; Valladeau Jenny; Zitvogel Laurence; Théry Clotilde; Amigorena Sebastian
Antigen presentation and T cell stimulation by dendritic cells.
Annual review of immunology 2002;20():621-67.
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2001: Ikarashi Y; Mikami R; Bendelac A; Terme M; Chaput N; Terada M; Tursz T; Angevin E; Lemonnier F A; Wakasugi H; Zitvogel L
Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: critical role for B7 in CD1d-dependent NKT cell interferon gamma production.
The Journal of experimental medicine 2001;194(8):1179-86.
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2001: Wolfers J; Lozier A; Raposo G; Regnault A; Théry C; Masurier C; Flament C; Pouzieux S; Faure F; Tursz T; Angevin E; Amigorena S; Zitvogel L
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.
Nature medicine 2001;7(3):297-303.
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2001: Andre F; Andersen M; Wolfers J; Lozier A; Raposo G; Serra V; Ruegg C; Flament C; Angevin E; Amigorena S; Zitvogel L
Exosomes in cancer immunotherapy: preclinical data.
Advances in experimental medicine and biology 2001;495():349-54.
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2000: Merad M; Angevin E; Wolfers J; Flament C; Lorenzi I; Triebel F; Escudier B; Zitvogel L
Generation of monocyte-derived dendritic cells from patients with renal cell cancer: modulation of their functional properties after therapy with biological response modifiers (IFN-alpha plus IL-2 and IL-12).
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(3):369-78.
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2000: Angevin E; André F; Zitvogel L
[Antitumor cellular immunotherapy: the breakthrough of dendritic cells]
Bulletin du cancer 2000;87(1):107-15.
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2000: Zitvogel L; Angevin E; Tursz T
Dendritic cell-based immunotherapy of cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11 Suppl 3():199-205.
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1999: Théry C; Regnault A; Garin J; Wolfers J; Zitvogel L; Ricciardi-Castagnoli P; Raposo G; Amigorena S
Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.
The Journal of cell biology 1999;147(3):599-610.
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1999: Zitvogel L; Fernandez N; Lozier A; Wolfers J; Regnault A; Raposo G; Amigorena S
Dendritic cells or their exosomes are effective biotherapies of cancer.
European journal of cancer (Oxford, England : 1990) 1999;35 Suppl 3():S36-8.
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1999: Fernandez N C; Lozier A; Flament C; Ricciardi-Castagnoli P; Bellet D; Suter M; Perricaudet M; Tursz T; Maraskovsky E; Zitvogel L
Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.
Nature medicine 1999;5(4):405-11.
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1998: Zitvogel L; Regnault A; Lozier A; Wolfers J; Flament C; Tenza D; Ricciardi-Castagnoli P; Raposo G; Amigorena S
Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes.
Nature medicine 1998;4(5):594-600.
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1997: Gahéry-Ségard H; Molinier-Frenkel V; Le Boulaire C; Saulnier P; Opolon P; Lengagne R; Gautier E; Le Cesne A; Zitvogel L; Venet A; Schatz C; Courtney M; Le Chevalier T; Tursz T; Guillet J G; Farace F
Phase I trial of recombinant adenovirus gene transfer in lung cancer. Longitudinal study of the immune responses to transgene and viral products.
The Journal of clinical investigation 1997;100(9):2218-26.
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