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Laurence Zitvogel

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Yuting Ma; Isabelle Martins; Stephen R Mattarollo; Laurie Menger; Mickaël Michaud; João Paulo Portela Catani; Frederic Schlemmer; Mark J Smyth; Eric Solary; Kim Steegh; Abdul Qader Sukkurwala; Philip R Taylor; Erika Vacchelli; Peter van Endert; Takahiro Yamazaki; Heng Yang; Laurence Zitvogel; Sandy Adjemian; Laetitia Aymeric; Nathalie Droin; Helene Duret; Lorenzo Galluzzi; Siamon Gordon; Dalil Hannani; Oliver Kepp; Roman Krzysiek; Guido Kroemer
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Federico Sandoval; Muhammed Suleman; Julien Taieb; Magali Terme; Marine Thiebaud; Thi Tran; Tzyy-choou Wu; Laurence Zitvogel; Gwennhael Autret; Cécile Badoual; Cécilia Bouguin; Michel-Francis Bureau; Olivier Clement; Claire Danel; Estelle Dransart; Guillaume Fraisse; Ludovic Freyburger; Wolf H Fridman; Alain Gey; Ludger Johannes; Odile Launay; Elie Marcheteau; Nathalie Merillon; Mevyn Nizard; Françoise Quintin-Colonna; Jennifer Richardson; Sabine Riffault; Eric Tartour
Mucosal imprinting of vaccine-induced CD8⁺ T cells is crucial to inhibit the growth of mucosal tumors.
Lisa M Coussens; Laurence Zitvogel; A Karolina Palucka
Neutralizing tumor-promoting chronic inflammation: a magic bullet?

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All Publications

2013: Yuting Ma; Isabelle Martins; Stephen R Mattarollo; Laurie Menger; Mickaël Michaud; João Paulo Portela Catani; Frederic Schlemmer; Mark J Smyth; Eric Solary; Kim Steegh; Abdul Qader Sukkurwala; Philip R Taylor; Erika Vacchelli; Peter van Endert; Takahiro Yamazaki; Heng Yang; Laurence Zitvogel; Sandy Adjemian; Laetitia Aymeric; Nathalie Droin; Helene Duret; Lorenzo Galluzzi; Siamon Gordon; Dalil Hannani; Oliver Kepp; Roman Krzysiek; Guido Kroemer
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Immunity 2013;38(4):729-41.
2013: Federico Sandoval; Muhammed Suleman; Julien Taieb; Magali Terme; Marine Thiebaud; Thi Tran; Tzyy-choou Wu; Laurence Zitvogel; Gwennhael Autret; Cécile Badoual; Cécilia Bouguin; Michel-Francis Bureau; Olivier Clement; Claire Danel; Estelle Dransart; Guillaume Fraisse; Ludovic Freyburger; Wolf H Fridman; Alain Gey; Ludger Johannes; Odile Launay; Elie Marcheteau; Nathalie Merillon; Mevyn Nizard; Françoise Quintin-Colonna; Jennifer Richardson; Sabine Riffault; Eric Tartour
Mucosal imprinting of vaccine-induced CD8⁺ T cells is crucial to inhibit the growth of mucosal tumors.
Science translational medicine 2013;5(172):172ra20.
2013: Lisa M Coussens; Laurence Zitvogel; A Karolina Palucka
Neutralizing tumor-promoting chronic inflammation: a magic bullet?
Science (New York, N.Y.) 2013;339(6117):286-91.
2013: Guido Kroemer; Lorenzo Galluzzi; Oliver Kepp; Laurence Zitvogel
Immunogenic cell death in cancer therapy.
Annual review of immunology 2013;31():51-72.
2012: Marcello Albanesi; Bruno Iannascoli; Jeanette H Leusen; Lynn E Macdonald; David A Mancardi; Andrew J Murphy; Laurence Zitvogel; Marc Daëron; Pierre Bruhns
Cutting edge: FcγRIII (CD16) and FcγRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(12):5513-7.
2012: Margret Ehlers; Benedikt Jacobs; Klaus L Meyer; Claudia Papewalis; Werner A Scherbaum; Sven Schinner; Wiebke Stenzel; Annette Thiel; Evelyn Ullrich; Holger S Willenberg; Laurence Zitvogel; René Deenen; Matthias Schott
Immunoregulatory natural killer cells suppress autoimmunity by down-regulating antigen-specific CD8+ T cells in mice.
Endocrinology 2012;153(9):4367-79.
2012: Sylvain Ladoire; Isabelle Martins; Mickaël Michaud; Vichnou Poirier-Colame; Mathias Rosenfeldt; Kevin M Ryan; Abdul Qader Sukkurwala; Eileen White; Laurence Zitvogel; Sandy Adjemian; Felipe Andreiuolo; Kariman Chaba; Lorenzo Galluzzi; Guido Kroemer
Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens.
Autophagy 2012;8(8):1175-84.
2012: Laurie Menger; Mickaël Michaud; Grégoire Mignot; Nazanine Modjtahedi; Frederic Schlemmer; Shensi Shen; Abdul Qader Sukkurwala; Eric Sulpice; Erika Vacchelli; Takahiro Yamazaki; Laurence Zitvogel; Sandy Adjemian; Fabrice André; Lorenzo Galluzzi; François Ghiringhelli; Xavier Gidrol; Oliver Kepp; Clara Locher; Yuting Ma; Isabelle Martins; Guido Kroemer
Cardiac glycosides exert anticancer effects by inducing immunogenic cell death.
Science translational medicine 2012;4(143):143ra99.
2012: Laurence Zitvogel; Isabelle Martins; Laetitia Aymeric; Dalil Hannani; Oliver Kepp; Guido Kroemer
[Antitumoral immunization during cancer chemotherapy].
Bulletin de l'Académie nationale de médecine 2012;196(6):1075-86.
2012: Magali Terme; Evelyn Ullrich; Sophie Viaud; Hideo Yagita; Laetitia Aymeric; Nathalie Chaput; Lieping Chen; Jerome Coudert; Mariapia Degli-Esposti; Mélanie Desbois; François Ghiringhelli; Gilles Kaplanski; Masashi Kato; Guido Kroemer; Salaheddine Mécheri; Kathrin Meinhardt; Armelle Prévost-Blondel; Bernard Ryffel; Joachim L Schultze; Eric Tartour; Laurence Zitvogel
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells.
Cancer research 2012;72(11):2757-67.
2012: Laurence Zitvogel; Franck Housseau
IKDCs or B220+ NK cells are pre-mNK cells.
Blood 2012;119(19):4345-6.
2012: Dalil Hannani; Guido Kroemer; Yuting Ma; Takahiro Yamazaki; Julie Déchanet-Merville; Laurence Zitvogel
Harnessing γδ T cells in anticancer immunotherapy.
Trends in immunology 2012;33(5):199-206.
2012: Laurence Zitvogel; Lorenzo Galluzzi; Oliver Kepp; Guido Kroemer
Inflammasomes in carcinogenesis and anticancer immune responses.
Nature immunology 2012;13(4):343-51.
2012: Isabelle Martins; Laurie Menger; Mickaël Michaud; Shensi Shen; Abdul Qader Sukkurwala; Erika Vacchelli; Laurence Zitvogel; Sandy Adjemian; Lorenzo Galluzzi; Oliver Kepp; Yuting Ma; Guido Kroemer
Premortem autophagy determines the immunogenicity of chemotherapy-induced cancer cell death.
Autophagy 2012;8(3):413-5.
2012: Christophe Caux; Laurence Zitvogel
Recent successes of cancer immunotherapy: a new dimension in personalized medicine?
Targeted oncology 2012;7(1):1-2.
2012: Lorenzo Galluzzi; Laura Senovilla; Laurence Zitvogel; Guido Kroemer
The secret ally: immunostimulation by anticancer drugs.
Nature reviews. Drug discovery 2012;11(3):215-33.
2012: Mélanie Desbois; Clara Locher; Sylvie Rusakiewicz; Laurence Zitvogel; Nathalie Chaput
Natural killer cells in non-hematopoietic malignancies.
Frontiers in immunology 2012;3():395.
2011: Laurence Zitvogel; Sebastian Amigorena; Jean-Luc Teillaud
[About Ralph M. Steinman and dendritic cells].
Médecine sciences : M/S 2011;27(11):1028-34.
2011: Dalil Hannani; Oliver Kepp; Guido Kroemer; Antonella Sistigu; Lorenzo Galluzzi; Laurence Zitvogel
Prerequisites for the antitumor vaccine-like effect of chemotherapy and radiotherapy.
Cancer journal (Sudbury, Mass.) 2011;17(5):351-8.
2011: Laurence Zitvogel; Guido Kroemer
Anticancer effects of imatinib via immunostimulation.
Nature medicine 2011;17(9):1050-1.
2011: Emanuela Martinuzzi; Diana Mittag; Gaetano Naselli; Laurence Zitvogel; Georgia Afonso; Christian Boitard; Nathalie Chaput; Béhazine Combadière; Marie-Claude Gagnerault; Leonard C Harrison; Roberto Mallone
acDCs enhance human antigen-specific T-cell responses.
Blood 2011;118(8):2128-37.
2011: Magali Terme; Evelyn Ullrich; Laetitia Aymeric; Kathrin Meinhardt; Mélanie Desbois; Nicolas Delahaye; Sophie Viaud; Bernard Ryffel; Hideo Yagita; Gilles Kaplanski; Armelle Prévost-Blondel; Masashi Kato; Joachim L Schultze; Eric Tartour; Guido Kroemer; Nathalie Chaput; Laurence Zitvogel
IL-18 induces PD-1-dependent immunosuppression in cancer.
Cancer research 2011;71(16):5393-9.
2011: Daniel M Andrews; Desiree A Anthony; Melvyn T Chow; Claire L Cotterell; Yoichiro Iwakura; Yuting Ma; Joseph A Trapani; Sally V Watt; Laurence Zitvogel; Shizuo Akira; Mark J Smyth
Homeostatic defects in interleukin 18-deficient mice contribute to protection against the lethal effects of endotoxin.
Immunology and cell biology 2011;89(6):739-46.
2011: Stephen R Mattarollo; Helene Duret; Sherene Loi; Yuting Ma; Laurence Zitvogel; Mark J Smyth
Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors.
Cancer research 2011;71(14):4809-20.
2011: Antonella Sistigu; Sophie Viaud; Laura Bracci; Nathalie Chaput; Enrico Proietti; Laurence Zitvogel
Immunomodulatory effects of cyclophosphamide and implementations for vaccine design.
Seminars in immunopathology 2011;33(4):369-83.
2011: Yuting Ma; Laetitia Aymeric; Clara Locher; Stephen R Mattarollo; Nicolas F Delahaye; Pablo Pereira; Laurent Boucontet; Lionel Apetoh; François Ghiringhelli; Noelia Casares; Juan José Lasarte; Goro Matsuzaki; Koichi Ikuta; Bernard Ryffel; Kamel Benlagha; Antoine Tesnière; Nicolas Ibrahim; Julie Déchanet-Merville; Nathalie Chaput; Mark J Smyth; Guido Kroemer; Laurence Zitvogel
Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.
The Journal of experimental medicine 2011;208(3):491-503.
2011: Laurence Zitvogel; Oliver Kepp; Guido Kroemer
Immune parameters affecting the efficacy of chemotherapeutic regimens.
Nature reviews. Clinical oncology 2011;8(3):151-60.
2011: Bruno Salaun; Laurence Zitvogel; Carine Asselin-Paturel; Yannis Morel; Karine Chemin; Clarisse Dubois; Catherine Massacrier; Rosa Conforti; Marie Pierre Chenard; Jean-Christophe Sabourin; Aicha Goubar; Serge Lebecque; Michel Pierres; Donata Rimoldi; Pedro Romero; Fabrice Andre
TLR3 as a biomarker for the therapeutic efficacy of double-stranded RNA in breast cancer.
Cancer research 2011;71(5):1607-14.
2011: Yuting Ma; R Conforti; Laetitia Aymeric; Clara Locher; Oliver Kepp; Guido Kroemer; Laurence Zitvogel
How to improve the immunogenicity of chemotherapy and radiotherapy.
Cancer metastasis reviews 2011;30(1):71-82.
2011: Oliver Kepp; Lorenzo Galluzzi; Isabelle Martins; Frederic Schlemmer; Sandy Adjemian; Mickael Michaud; Abdul Qader Sukkurwala; Laurie Menger; Laurence Zitvogel; Guido Kroemer
Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy.
Cancer metastasis reviews 2011;30(1):61-9.
2011: Lionel Apetoh; Clara Locher; François Ghiringhelli; Guido Kroemer; Laurence Zitvogel
Harnessing dendritic cells in cancer.
Seminars in immunology 2011;23(1):42-9.
2011: Sophie Viaud; Caroline Flament; Mustapha Zoubir; Patricia Pautier; Axel LeCesne; Vincent Ribrag; Jean-Charles Soria; Virginie Marty; Philippe Vielh; Caroline Robert; Nathalie Chaput; Laurence Zitvogel
Cyclophosphamide induces differentiation of Th17 cells in cancer patients.
Cancer research 2011;71(3):661-5.
2011: Yuting Ma; Laetitia Aymeric; Clara Locher; Guido Kroemer; Laurence Zitvogel
The dendritic cell-tumor cross-talk in cancer.
Current opinion in immunology 2011;23(1):146-52.
2011: Jean-Marc Doisne; Valérie Soulard; Chantal Bécourt; Latiffa Amniai; Pauline Henrot; Colin Havenar-Daughton; Charlène Blanchet; Laurence Zitvogel; Bernhard Ryffel; Jean-Marc Cavaillon; Julien C Marie; Isabelle Couillin; Kamel Benlagha
Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(2):662-6.
2011: Eric Vivier; David H Raulet; Alessandro Moretta; Michael A Caligiuri; Laurence Zitvogel; Lewis L Lanier; Wayne M Yokoyama; Sophie Ugolini
Innate or adaptive immunity? The example of natural killer cells.
Science (New York, N.Y.) 2011;331(6013):44-9.
2011: Wolf H Fridman; Jérôme Galon; Franck Pagès; Catherine Sautès-Fridman; Eric Tartour; Jean-Luc Teillaud; Laurence Zitvogel; Jessica Zucman-Rossi; Guido Kroemer
The ultimate goal of curative anti-cancer therapies: inducing an adaptive anti-tumor immune response.
Frontiers in immunology 2011;2():66.
2011: G Kroemer; Yuting Ma; Isabelle Martins; Laurie Menger; Mickaël Michaud; Abdul Qader Sukkurwala; Erika Vacchelli; Sandy Adjemian; Oliver Kepp; Laurence Zitvogel
[Contributions of immunogenic cell death to the efficacy of anticancer chemotherapy].
Bulletin et mémoires de l'Académie royale de médecine de Belgique 2011;166(3-4):130-8; discussion 139-40.
2011: Mustapha Zoubir; Caroline Flament; Abdelaziz Gdoura; Rastilav Bahleda; Elena Litvinova; Vassili Soumelis; Rosa Conforti; Sophie Viaud; Jean-Charles Soria; Guido Kroemer; Laurence Zitvogel; Nathalie Chaput
An inhibitor of cyclin-dependent kinases suppresses TLR signaling and increases the susceptibility of cancer patients to herpesviridae.
Cell cycle (Georgetown, Tex.) 2011;10(1):118-26.
2011: Sophie Viaud; Stéphanie Ploix; Valérie Lapierre; Clotilde Théry; Pierre-Henri Commere; Dominique Tramalloni; Kevin Gorrichon; Pauline Virault-Rocroy; Thomas Tursz; Olivier Lantz; Laurence Zitvogel; Nathalie Chaput
Updated technology to produce highly immunogenic dendritic cell-derived exosomes of clinical grade: a critical role of interferon-γ.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011;34(1):65-75.
2010: Laurence Zitvogel; Oliver Kepp; Laetitia Aymeric; Yuting Ma; Clara Locher; Nicolas F Delahaye; Fabrice André; Guido Kroemer
Integration of host-related signatures with cancer cell-derived predictors for the optimal management of anticancer chemotherapy.
Cancer research 2010;70(23):9538-43.
2010: Laurence Zitvogel; Guido Kroemer
The multifaceted granulysin.
Blood 2010;116(18):3379-80.
2010: Clara Locher; R Conforti; Laetitia Aymeric; Yuting Ma; Takahiro Yamazaki; Sylvie Rusakiewicz; Antoine Tesnière; François Ghiringhelli; Lionel Apetoh; Yannis Morel; Jean-Philippe Girard; Guido Kroemer; Laurence Zitvogel
Desirable cell death during anticancer chemotherapy.
Annals of the New York Academy of Sciences 2010;1209():99-108.
2010: Isabelle Martins; Oliver Kepp; Lorenzo Galluzzi; Laura Senovilla; Frederic Schlemmer; Sandy Adjemian; Laurie Menger; Mickael Michaud; Laurence Zitvogel; Guido Kroemer
Surface-exposed calreticulin in the interaction between dying cells and phagocytes.
Annals of the New York Academy of Sciences 2010;1209():77-82.
2010: Oliver Kepp; Abdelaziz Gdoura; Isabelle Martins; Theocharis Panaretakis; Frederic Schlemmer; Antoine Tesniere; Gian Maria Fimia; Fabiola Ciccosanti; Anne Burgevin; Mauro Piacentini; Paul Eggleton; Philip J Young; Laurence Zitvogel; Peter van Endert; Guido Kroemer
Lysyl tRNA synthetase is required for the translocation of calreticulin to the cell surface in immunogenic death.
Cell cycle (Georgetown, Tex.) 2010;9(15):3072-7.
2010: Laurence Zitvogel; Guido Kroemer
Targeting dendritic cell metabolism in cancer.
Nature medicine 2010;16(8):858-9.
2010: Antoine Tesniere; Nassera Abermil; Frederic Schlemmer; Noelia Casares; Oliver Kepp; Marie Pequignot; Mickael Michaud; Isabelle Martins; Laura Senovilla; Laurence Zitvogel; Guido Kroemer
In vivo depletion of T lymphocyte-specific transcription factors by RNA interference.
Cell cycle (Georgetown, Tex.) 2010;9(14):2830-5.
2010: Laurence Zitvogel; Oliver Kepp; Laura Senovilla; Laurie Menger; Nathalie Chaput; Guido Kroemer
Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(12):3100-4.
2010: Yuting Ma; Oliver Kepp; François Ghiringhelli; Lionel Apetoh; Laetitia Aymeric; Clara Locher; Antoine Tesniere; Isabelle Martins; André Ly; Nicole M Haynes; Mark J Smyth; Guido Kroemer; Laurence Zitvogel
Chemotherapy and radiotherapy: cryptic anticancer vaccines.
Seminars in immunology 2010;22(3):113-24.
2010: Mitchell S Cairo; Craig T Jordan; Carlo C Maley; K.S. Chao; Ari Melnick; Scott A Armstrong; Warren Shlomchik; Jeff Molldrem; Soldano Ferrone; CRYSTAL MACKALL; Laurence Zitvogel; Michael Bishop; Sergio Giralt; Carl H June
NCI first International Workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on the biological considerations of hematological relapse following allogeneic stem cell transplantation unrelated to graft-versus-tumor effects: state of the science.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(6):709-28.
2010: Lorenzo Galluzzi; O Kepp; E Morselli; Ilio Vitale; Laura Senovilla; M Pinti; Laurence Zitvogel; Guido Kroemer
Viral strategies for the evasion of immunogenic cell death.
Journal of internal medicine 2010;267(5):526-42.
2010: Laurence Zitvogel; Oliver Kepp; Guido Kroemer
Decoding cell death signals in inflammation and immunity.
Cell 2010;140(6):798-804.
2010: Oliver Kepp; Lorenzo Galluzzi; Laurence Zitvogel; Guido Kroemer
Pyroptosis - a cell death modality of its kind?
European journal of immunology 2010;40(3):627-30.
2010: Moustapha Zoubir; Thomas Tursz; Cédric Ménard; Laurence Zitvogel; Nathalie Chaput
Imatinib mesylate (Gleevec): targeted therapy against cancer with immune properties.
Endocrine, metabolic & immune disorders drug targets 2010;10(1):1-7.
2010: Sophie Viaud; Clotilde Théry; Stéphanie Ploix; Thomas Tursz; Valérie Lapierre; Olivier Lantz; Laurence Zitvogel; Nathalie Chaput
Dendritic cell-derived exosomes for cancer immunotherapy: what's next?
Cancer research 2010;70(4):1281-5.
2010: Lorenzo Galluzzi; Oliver Kepp; Laurence Zitvogel; Guido Kroemer
Bacterial invasion: linking autophagy and innate immunity.
Current biology : CB 2010;20(3):R106-8.
2010: Alfredo Criollo; Laura Senovilla; Hélène Authier; Maria Chiara Maiuri; Eugenia Morselli; Ilio Vitale; Oliver Kepp; Ezgi Tasdemir; Lorenzo Galluzzi; Shensi Shen; Maximilien Tailler; Nicolas Delahaye; Antoine Tesniere; Daniela De Stefano; Aména Ben Younes; Francis Harper; Gérard Pierron; Sergio Lavandero; Laurence Zitvogel; Alain Israel; Véronique Baud; Guido Kroemer
The IKK complex contributes to the induction of autophagy.
The EMBO journal 2010;29(3):619-31.
2010: Fanny Chalmin; Sylvain Ladoire; Grégoire Mignot; Julie Vincent; Mélanie Bruchard; Jean-Paul Remy-Martin; Wilfrid Boireau; Alain Rouleau; Benoit Simon; David Lanneau; Aurélie de Thonel; Gabriele Multhoff; Arlette Hamman; François Martin; Bruno Chauffert; Eric Solary; Laurence Zitvogel; Carmen Garrido; Bernhard RYFFEL; Christophe Borg; Lionel Apetoh; Cédric Rébé; François Ghiringhelli
Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.
The Journal of clinical investigation 2010;120(2):457-71.
2010: Laetitia Aymeric; Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; Isabelle Martins; Guido Kroemer; Mark J Smyth; Laurence Zitvogel
Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity.
Cancer research 2010;70(3):855-8.
2010: Antoine Tesniere; F Schlemmer; V Boige; O Kepp; I Martins; François Ghiringhelli; L Aymeric; M Michaud; Lionel Apetoh; L Barault; J Mendiboure; J-P Pignon; V Jooste; Peter van Endert; M Ducreux; Laurence Zitvogel; F Piard; Guido Kroemer
Immunogenic death of colon cancer cells treated with oxaliplatin.
Oncogene 2010;29(4):482-91.
2010: R Conforti; Yuting Ma; Yannis Morel; Carine Paturel; Magali Terme; Sophie Viaud; Bernhard RYFFEL; Maria Ferrantini; Ravindra Uppaluri; Robert Schreiber; Christophe Combadière; Nathalie Chaput; Fabrice André; Guido Kroemer; Laurence Zitvogel
Opposing effects of toll-like receptor (TLR3) signaling in tumors can be therapeutically uncoupled to optimize the anticancer efficacy of TLR3 ligands.
Cancer research 2010;70(2):490-500.
2010: Alfredo Criollo; Laura Senovilla; Hélène Authier; Maria Chiara Maiuri; Eugenia Morselli; Ilio Vitale; Oliver Kepp; Ezgi Tasdemir; Lorenzo Galluzzi; Shensi Shen; Maximilien Tailler; Nicolas Delahaye; Antoine Tesniere; Daniela De Stefano; Aména Ben Younes; Francis Harper; Gérard Pierron; Sergio Lavandero; Laurence Zitvogel; Alain Israel; Véronique Baud; Guido Kroemer
IKK connects autophagy to major stress pathways.
Autophagy 2010;6(1):189-91.
2009: Oliver Kepp; Lorenzo Galluzzi; Fabrizio Giordanetto; Antoine Tesniere; Ilio Vitale; Isabelle Martins; Frederic Schlemmer; Sandy Adjemian; Laurence Zitvogel; Guido Kroemer
Disruption of the PP1/GADD34 complex induces calreticulin exposure.
Cell cycle (Georgetown, Tex.) 2009;8(23):3971-7.
2009: Isabelle Martins; Antoine Tesniere; Oliver Kepp; Mickael Michaud; Frederic Schlemmer; Laura Senovilla; Claire Séror; Didier Métivier; Jean-Luc PERFETTINI; Laurence Zitvogel; Guido Kroemer
Chemotherapy induces ATP release from tumor cells.
Cell cycle (Georgetown, Tex.) 2009;8(22):3723-8.
2009: François Ghiringhelli; Lionel Apetoh; Antoine Tesniere; Laetitia Aymeric; Yuting Ma; Carla Ortiz; Karim Vermaelen; Theocharis Panaretakis; Grégoire Mignot; Evelyn Ullrich; Jean-Luc PERFETTINI; Frédéric Schlemmer; Ezgi Tasdemir; Martin Uhl; Pierre Génin; Ahmet Civas; Bernhard RYFFEL; Jean Kanellopoulos; Jürg Tschopp; Fabrice André; Rosette Lidereau; Nicole M McLaughlin; Nicole M Haynes; Mark J Smyth; Guido Kroemer; Laurence Zitvogel
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
Nature medicine 2009;15(10):1170-8.
2009: Clara Locher; Sylvie Rusakiewicz; Antoine Tesnière; François Ghiringhelli; Lionel Apetoh; Guido Kroemer; Laurence Zitvogel
Witch hunt against tumor cells enhanced by dendritic cells.
Annals of the New York Academy of Sciences 2009;1174():51-60.
2009: Magali Terme; Grégoire Mignot; Evelyn Ullrich; Mathieu Bonmort; Véronique Minard-Colin; Alexandra Jacquet; Joachim L Schultze; Guido Kroemer; CLAUDE LECLERC; Nathalie Chaput; Laurence Zitvogel
The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells.
Cancer research 2009;69(16):6590-7.
2009: Laurence Zitvogel; Guido Kroemer
Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects.
The Journal of clinical investigation 2009;119(8):2127-30.
2009: Douglas R Green; Thomas Ferguson; Laurence Zitvogel; Guido Kroemer
Immunogenic and tolerogenic cell death.
Nature reviews. Immunology 2009;9(5):353-63.
2009: Cédric Ménard; Jean-Yves Blay; Christophe Borg; Stefan Michiels; François Ghiringhelli; Caroline Robert; Céline Nonn; Nathalie Chaput; Julien Taïeb; Nicolas F Delahaye; Caroline Flament; Jean-François Emile; Axel Le Cesne; Laurence Zitvogel
Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients.
Cancer research 2009;69(8):3563-9.
2009: Oliver Kepp; Antoine Tesniere; Frederic Schlemmer; Mickael Michaud; Laura Senovilla; Laurence Zitvogel; Guido Kroemer
Immunogenic cell death modalities and their impact on cancer treatment.
Apoptosis : an international journal on programmed cell death 2009;14(4):364-75.
2009: Oliver Kepp; Laura Senovilla; Lorenzo Galluzzi; Theocharis Panaretakis; Antoine Tesniere; Frederic Schlemmer; Frank Madeo; Laurence Zitvogel; Guido Kroemer
Viral subversion of immunogenic cell death.
Cell cycle (Georgetown, Tex.) 2009;8(6):860-9.
2009: Theocharis Panaretakis; Oliver Kepp; Ulf Brockmeier; Antoine Tesniere; Ann-Charlotte Bjorklund; Daniel C Chapman; Michael Durchschlag; Nicholas Joza; Gérard Pierron; Peter van Endert; Junying Yuan; Laurence Zitvogel; Frank Madeo; David B Williams; Guido Kroemer
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death.
The EMBO journal 2009;28(5):578-90.
2009: Frank Madeo; Michael Durchschlag; Oliver Kepp; Theocharis Panaretakis; Laurence Zitvogel; Kai-Uwe Fröhlich; Guido Kroemer
Phylogenetic conservation of the preapoptotic calreticulin exposure pathway from yeast to mammals.
Cell cycle (Georgetown, Tex.) 2009;8(4):639-42.
2009: Sophie Viaud; Magali Terme; Caroline Flament; Julien Taieb; Fabrice André; Sophie Novault; Bernard Escudier; Caroline Robert; Sophie Caillat-Zucman; Thomas Tursz; Laurence Zitvogel; Nathalie Chaput
Dendritic cell-derived exosomes promote natural killer cell activation and proliferation: a role for NKG2D ligands and IL-15Ralpha.
PloS one 2009;4(3):e4942.
2009: Oliver Kepp; Antoine Tesniere; Laurence Zitvogel; Guido Kroemer
The immunogenicity of tumor cell death.
Current opinion in oncology 2009;21(1):71-6.
2008: Laurence Zitvogel; Guido Kroemer
The dilemma of anticancer therapy: tumor-specific versus immune effects.
Blood 2008;112(12):4364-5.
2008: Jean R Pallandre; Konrad Krzewski; Romain Bedel; Bernhard RYFFEL; Anne Caignard; Pierre-Simon Rohrlich; Xavier Pivot; Pierre Tiberghien; Laurence Zitvogel; Jack L Strominger; Christophe Borg
Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activation.
Blood 2008;112(12):4420-4.
2008: Stephan Roux; Lionel Apetoh; Fanny Chalmin; Sylvain Ladoire; Grégoire Mignot; Pierre-Emmanuel Puig; Gregoire Lauvau; Laurence Zitvogel; François Martin; Bruno Chauffert; Hideo Yagita; Eric Solary; François Ghiringhelli
CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer.
The Journal of clinical investigation 2008;118(11):3751-61.
2008: Nathalie Chaput; R Conforti; Sophie Viaud; Alain Spatz; Laurence Zitvogel
The Janus face of dendritic cells in cancer.
Oncogene 2008;27(45):5920-31.
2008: Laurence Zitvogel; Antoine Tesniere; Lionel Apetoh; François Ghiringhelli; Guido Kroemer
[Immunological aspects of anticancer chemotherapy].
Bulletin de l'Académie nationale de médecine 2008;192(7):1469-87; discussion 1487-9.
2008: Laurence Zitvogel; Guido Kroemer
Introduction: the immune response against dying cells.
Current opinion in immunology 2008;20(5):501-3.
2008: Antoine Tesniere; Lionel Apetoh; François Ghiringhelli; Nicholas Joza; Theocharis Panaretakis; Oliver Kepp; Frederic Schlemmer; Laurence Zitvogel; Guido Kroemer
Immunogenic cancer cell death: a key-lock paradigm.
Current opinion in immunology 2008;20(5):504-11.
2008: Mathieu Bonmort; Marc Dalod; Grégoire Mignot; Evelyn Ullrich; Nathalie Chaput; Laurence Zitvogel
Killer dendritic cells: IKDC and the others.
Current opinion in immunology 2008;20(5):558-65.
2008: Theocharis Panaretakis; Nicholas Joza; Nazanine Modjtahedi; Antoine Tesniere; Ilio Vitale; M Durchschlag; Gian Maria Fimia; O Kepp; Mauro Piacentini; K-U Froehlich; Peter van Endert; Laurence Zitvogel; Frank Madeo; Guido Kroemer
The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death.
Cell death and differentiation 2008;15(9):1499-509.
2008: Stephan Roux; Claire Bernat; Bassim Al-Sakere; François Ghiringhelli; Paule Opolon; Antoine F Carpentier; Laurence Zitvogel; Lluis M Mir; Caroline Robert
Tumor destruction using electrochemotherapy followed by CpG oligodeoxynucleotide injection induces distant tumor responses.
Cancer immunology, immunotherapy : CII 2008;57(9):1291-300.
2008: Cédric Ménard; François Ghiringhelli; Stephan Roux; Nathalie Chaput; Christine Mateus; Ursula Grohmann; Sophie Caillat-Zucman; Laurence Zitvogel; Caroline Robert
Ctla-4 blockade confers lymphocyte resistance to regulatory T-cells in advanced melanoma: surrogate marker of efficacy of tremelimumab?
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(16):5242-9.
2008: Evelyn Ullrich; Mathieu Bonmort; Grégoire Mignot; Benedikt Jacobs; Daniela Bosisio; Silvano Sozzani; Abdelali JALIL; Fawzia Louache; Elena Bulanova; Frederic Geissman; Bernhard RYFFEL; Nathalie Chaput; Silvia Bulfone-Paus; Laurence Zitvogel
Trans-presentation of IL-15 dictates IFN-producing killer dendritic cells effector functions.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):7887-97.
2008: Laurence Zitvogel; Lionel Apetoh; François Ghiringhelli; Fabrice André; Antoine Tesniere; Guido Kroemer
The anticancer immune response: indispensable for therapeutic success?
The Journal of clinical investigation 2008;118(6):1991-2001.
2008: Lionel Apetoh; Antoine Tesniere; François Ghiringhelli; Guido Kroemer; Laurence Zitvogel
Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies.
Cancer research 2008;68(11):4026-30.
2008: Grégoire Mignot; Evelyn Ullrich; Mathieu Bonmort; Cédric Ménard; Lionel Apetoh; Julien Taieb; Daniela Bosisio; Silvano Sozzani; Maria Ferrantini; Jürg Schmitz; Matthias Mack; Bernhard RYFFEL; Silvia Bulfone-Paus; Laurence Zitvogel; Nathalie Chaput
The critical role of IL-15 in the antitumor effects mediated by the combination therapy imatinib and IL-2.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6477-83.
2008: Laurence Zitvogel; Grégoire Mignot; Mathieu Bonmort; Evelyn Ullrich; Nathalie Chaput
[IKDC: killer dendritic cells or antigen-presenting NK cells?].
Médecine sciences : M/S 2008;24(5):525-8.
2008: Magali Terme; Evelyn Ullrich; Nicolas F Delahaye; Nathalie Chaput; Laurence Zitvogel
Natural killer cell-directed therapies: moving from unexpected results to successful strategies.
Nature immunology 2008;9(5):486-94.
2008: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; M Obeid; Grégoire Mignot; Evelyn Ullrich; Guido Kroemer; Laurence Zitvogel
Cancer is not just a disease of a tissue: it is a host disease. How to reactivate host defense against tumors using conventional therapies of cancer?
Annales d'endocrinologie 2008;69(2):151-2.
2008: Magali Terme; Nathalie Chaput; Behazine Combadiere; Averil Ma; Toshiaki Ohteki; Laurence Zitvogel
Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4679-86.
2008: Lionel Apetoh; Grégoire Mignot; Theocharis Panaretakis; Guido Kroemer; Laurence Zitvogel
Immunogenicity of anthracyclines: moving towards more personalized medicine.
Trends in molecular medicine 2008;14(4):141-51.
2008: Sophie Viaud; Evelyn Ullrich; Laurence Zitvogel; Nathalie Chaput
Exosomes for the treatment of human malignancies.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(2):82-8.
2008: Evelyn Ullrich; Nathalie Chaput; Laurence Zitvogel
Killer dendritic cells and their potential role in immunotherapy.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(2):75-81.
2008: Evelyn Ullrich; Cédric Ménard; Caroline Flament; Magali Terme; Grégoire Mignot; Mathieu Bonmort; Jöel Plumas; Laurence Chaperot; Nathalie Chaput; Laurence Zitvogel
Dendritic cells and innate defense against tumor cells.
Cytokine & growth factor reviews 2008;19(1):79-92.
2008: Roberta Tufi; Theocharis Panaretakis; Katiuscia Bianchi; Alfredo Criollo; Barbara Fazi; Federica Di Sano; Antoine Tesniere; O Kepp; P Paterlini-Brechot; Laurence Zitvogel; Mauro Piacentini; Gyorgy Szabadkai; Guido Kroemer
Reduction of endoplasmic reticulum Ca2+ levels favors plasma membrane surface exposure of calreticulin.
Cell death and differentiation 2008;15(2):274-82.
2008: Laurence Zitvogel; Lionel Apetoh; François Ghiringhelli; Guido Kroemer
Immunological aspects of cancer chemotherapy.
Nature reviews. Immunology 2008;8(1):59-73.
2008: Laurence Zitvogel; Guido Kroemer
The immune response against dying tumor cells: avoid disaster, achieve cure.
Cell death and differentiation 2008;15(1):1-2.
2008: Antoine Tesniere; Theocharis Panaretakis; O Kepp; Lionel Apetoh; François Ghiringhelli; Laurence Zitvogel; Guido Kroemer
Molecular characteristics of immunogenic cancer cell death.
Cell death and differentiation 2008;15(1):3-12.
2008: Evelyn Ullrich; Mathieu Bonmort; Grégoire Mignot; Guido Kroemer; Laurence Zitvogel
Tumor stress, cell death and the ensuing immune response.
Cell death and differentiation 2008;15(1):21-8.
2007: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; Alfredo Criollo; Carla Ortiz; Rosette Lidereau; Christophe Mariette; Nathalie Chaput; Jean-Paul Mira; Suzette Delaloge; Fabrice André; Thomas Tursz; Guido Kroemer; Laurence Zitvogel
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy.
Immunological reviews 2007;220():47-59.
2007: Michel Obeid; Antoine Tesniere; Theocharis Panaretakis; Roberta Tufi; Nick Joza; Peter van Endert; François Ghiringhelli; Lionel Apetoh; Nathalie Chaput; Caroline Flament; Evelyn Ullrich; Stéphane de Botton; Laurence Zitvogel; Guido Kroemer
Ecto-calreticulin in immunogenic chemotherapy.
Immunological reviews 2007;220():22-34.
2007: Guido Kroemer; Laurence Zitvogel
Death, danger, and immunity: an infernal trio.
Immunological reviews 2007;220():5-7.
2007: Nathalie Chaput; Stéphane de Botton; Michel Obeid; Lionel Apetoh; François Ghiringhelli; Theocharis Panaretakis; Caroline Flament; Laurence Zitvogel; Guido Kroemer
Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference.
Journal of molecular medicine (Berlin, Germany) 2007;85(10):1069-76.
2007: Michel Obeid; Theocharis Panaretakis; Nick Joza; Roberta Tufi; Antoine Tesniere; Peter van Endert; Laurence Zitvogel; Guido Kroemer
Calreticulin exposure is required for the immunogenicity of gamma-irradiation and UVC light-induced apoptosis.
Cell death and differentiation 2007;14(10):1848-50.
2007: Michel Obeid; Theocharis Panaretakis; Antoine Tesniere; Nick Joza; Roberta Tufi; Lionel Apetoh; François Ghiringhelli; Laurence Zitvogel; Guido Kroemer
Leveraging the immune system during chemotherapy: moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenic.
Cancer research 2007;67(17):7941-4.
2007: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; Michel Obeid; Carla Ortiz; Alfredo Criollo; Grégoire Mignot; M Chiara Maiuri; Evelyn Ullrich; Patrick Saulnier; Huan Yang; Sebastian Amigorena; Bernhard RYFFEL; Franck J Barrat; Paul Saftig; Francis Levi; Rosette Lidereau; Catherine Nogues; Jean-Paul Mira; Agnès Chompret; Virginie Joulin; Françoise Clavel-Chapelon; Jean Bourhis; Fabrice André; Suzette Delaloge; Thomas Tursz; Guido Kroemer; Laurence Zitvogel
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.
Nature medicine 2007;13(9):1050-9.
2007: Lorenzo Galluzzi; M Chiara Maiuri; Ilio Vitale; H Zischka; Maria Castedo; Laurence Zitvogel; Guido Kroemer
Cell death modalities: classification and pathophysiological implications.
Cell death and differentiation 2007;14(7):1237-43.
2007: Mathieu Bonmort; Evelyn Ullrich; Grégoire Mignot; Bénédikt Jacobs; Nathalie Chaput; Laurence Zitvogel
Interferon-gamma is produced by another player of innate immune responses: the interferon-producing killer dendritic cell (IKDC).
Biochimie 2007;89(6-7):872-7.
2007: François Ghiringhelli; Cedric Menard; Pierre-Emmanuel Puig; Sylvain Ladoire; Stephan Roux; François Martin; Eric Solary; Axel Le Cesne; Laurence Zitvogel; Bruno Chauffert
Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients.
Cancer immunology, immunotherapy : CII 2007;56(5):641-8.
2007: François Ghiringhelli; Lionel Apetoh; Franck Housseau; Guido Kroemer; Laurence Zitvogel
Links between innate and cognate tumor immunity.
Current opinion in immunology 2007;19(2):224-31.
2007: Lionel Apetoh; Michel Obeid; Antoine Tesniere; François Ghiringhelli; Gian Maria Fimia; Mauro Piacentini; Guido Kroemer; Laurence Zitvogel
Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells.
Cancer genomics & proteomics 2007;4(2):65-70.
2007: Lionel Apetoh; François Ghiringhelli; Laurence Zitvogel
[Calreticulin dictates the immunogenicity of anti-cancer chemotherapy and radiotherapy].
Médecine sciences : M/S 2007;23(3):257-8.
2007: Evelyn Ullrich; Mathieu Bonmort; Grégoire Mignot; Nathalie Chaput; Julien Taieb; Cédric Ménard; Sophie Viaud; Thomas Tursz; Guido Kroemer; Laurence Zitvogel
Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells.
Cancer research 2007;67(3):851-3.
2007: Michel Obeid; Antoine Tesniere; François Ghiringhelli; Gian Maria Fimia; Lionel Apetoh; Jean-Luc PERFETTINI; Maria Castedo; Grégoire Mignot; Theocharis Panaretakis; Noelia Casares; Didier Métivier; Nathanael Larochette; Peter van Endert; Fabiola Ciccosanti; Mauro Piacentini; Laurence Zitvogel; Guido Kroemer
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Nature medicine 2007;13(1):54-61.
2006: Maria Castedo; Arnaud Coquelle; Ilio Vitale; Sonia Vivet; Shahul Mouhamad; Sophie Viaud; Laurence Zitvogel; Guido Kroemer
Selective resistance of tetraploid cancer cells against DNA damage-induced apoptosis.
Annals of the New York Academy of Sciences 2006;1090():35-49.
2006: Antoine Tesniere; Laurence Zitvogel; Guido Kroemer
The immune system: taming and unleashing cancer.
Discovery medicine 2006;6(36):211-6.
2006: François Ghiringhelli; Cédric Ménard; Francois Martin; Laurence Zitvogel
The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression.
Immunological reviews 2006;214():229-38.
2006: Laurence Zitvogel; Antoine Tesniere; Guido Kroemer
Cancer despite immunosurveillance: immunoselection and immunosubversion.
Nature reviews. Immunology 2006;6(10):715-27.
2006: Nathalie Chaput; Caroline Flament; Sophie Viaud; Julien Taieb; Stephan Roux; Alain Spatz; Fabrice André; Jean-Bernard LePecq; Muriel Boussac; Jérôme Garin; Sebastian Amigorena; Clotilde Théry; Laurence Zitvogel
Dendritic cell derived-exosomes: biology and clinical implementations.
Journal of leukocyte biology 2006;80(3):471-8.
2006: Maria Castedo; Arnaud Coquelle; Sonia Vivet; Ilio Vitale; Audrey Kauffmann; Philippe Dessen; Marie O Pequignot; Noelia Casares; Alexander Valent; Shahul Mouhamad; Elise Schmitt; Nazanine Modjtahedi; William Vainchenker; Laurence Zitvogel; Vladimir Lazar; Carmen Garrido; Guido Kroemer
Apoptosis regulation in tetraploid cancer cells.
The EMBO journal 2006;25(11):2584-95.
2006: Nathalie Chaput; Julien Taieb; Evelyn Ullrich; Laurence Zitvogel
[A new dendritic cell implicated in antitumoral immunity].
Médecine sciences : M/S 2006;22(6-7):567-8.
2006: Nathalie Chaput; Julien Taieb; Laurence Zitvogel
[Innate defence against tumor cells: the killer cell IKDC].
Bulletin du cancer 2006;93(5):449-51.
2006: Grégoire Mignot; S Roux; Clotilde Thery; Elodie Ségura; Laurence Zitvogel
Prospects for exosomes in immunotherapy of cancer.
Journal of cellular and molecular medicine 2006;10(2):376-88.
2006: Julien Taieb; Nathalie Chaput; Noël Emile Célestin Schartz; Stéphan Roux; Sophie Novault; Cédric Ménard; François Ghiringhelli; Magali Terme; Antoine F Carpentier; Guillaume Darrasse-Jèze; Guillaume Darrasse-Jèse; François Lemonnier; Laurence Zitvogel
Chemoimmunotherapy of tumors: cyclophosphamide synergizes with exosome based vaccines.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):2722-9.
2006: François Ghiringhelli; Laurence Zitvogel
[Vaccine strategies against melanoma].
Médecine sciences : M/S 2006;22(2):183-7.
2006: Julien Taieb; Nathalie Chaput; Cédric Ménard; Lionel Apetoh; Evelyn Ullrich; Mathieu Bonmort; Marie Péquignot; Noelia Casares; Magali Terme; Caroline Flament; Paule Opolon; Yann Lecluse; Didier Métivier; Elena Tomasello; Eric Vivier; François Ghiringhelli; François Martin; David Klatzmann; Thierry Poynard; Thomas Tursz; Graça Raposo; Hideo Yagita; Bernard Ryffel; Guido Kroemer; Laurence Zitvogel
A novel dendritic cell subset involved in tumor immunosurveillance.
Nature medicine 2006;12(2):214-9.
2006: Laurence Zitvogel; Magali Terme; Christophe Borg; Trinchieri Giorgio
Dendritic cell-NK cell cross-talk: regulation and physiopathology.
Current topics in microbiology and immunology 2006;298():157-74.
2005: Noelia Casares; Marie O Pequignot; Antoine Tesniere; François Ghiringhelli; Stéphan Roux; Nathalie Chaput; Elise Schmitt; Ahmed Hamai; Sandra Hervas-Stubbs; Michel Obeid; Frédéric Coutant; Didier Métivier; Evelyne Pichard; Pierre Aucouturier; Gérard Pierron; Carmen Garrido; Laurence Zitvogel; Guido Kroemer
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death.
The Journal of experimental medicine 2005;202(12):1691-701.
2005: Laurence Zitvogel; Thomas Tursz
In vivo veritas.
Nature biotechnology 2005;23(11):1372-4.
2005: François Ghiringhelli; Cédric Ménard; Magali Terme; Caroline Flament; Julien Taieb; Nathalie Chaput; Pierre-Emmanuel Puig; Sophie Novault; Bernard Escudier; Eric Vivier; Axel Lecesne; Caroline Robert; Jean-Yves Blay; Jacky Bernard; Sophie Caillat-Zucman; Antonio Freitas; Thomas Tursz; Orianne Wagner-Ballon; Claude Capron; William Vainchencker; François Martin; Laurence Zitvogel
CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner.
The Journal of experimental medicine 2005;202(8):1075-85.
2005: François Ghiringhelli; Pierre-Emmanuel Puig; Stephan Roux; Arnaud Parcellier; Elise Schmitt; Eric Solary; Guido Kroemer; François Martin; Bruno Chauffert; Laurence Zitvogel
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation.
The Journal of experimental medicine 2005;202(7):919-29.
2005: Noël Emile Célestin Schartz; Nathalie Chaput; Julien Taieb; Pierre Bonnaventure; Hélène Trébeden-Nègre; Magali Terme; Cédric Ménard; Céleste Lebbé; Anneliese Schimpl; Patrice Ardouin; Laurence Zitvogel
IL-2 production by dendritic cells is not critical for the activation of cognate and innate effectors in draining lymph nodes.
European journal of immunology 2005;35(10):2840-50.
2005: Thierry Walzer; Marc Dalod; Scott H Robbins; Laurence Zitvogel; Eric Vivier
Natural-killer cells and dendritic cells: "l'union fait la force".
Blood 2005;106(7):2252-8.
2005: Thierry Walzer; Marc Dalod; Eric Vivier; Laurence Zitvogel
Natural killer cell-dendritic cell crosstalk in the initiation of immune responses.
Expert opinion on biological therapy 2005;5 Suppl 1():S49-59.
2005: Nathalie Chaput; Julien Taïeb; Noël Emile Célestin Schartz; Caroline Flament; Sophie Novault; Fabrice André; Laurence Zitvogel
The potential of exosomes in immunotherapy of cancer.
Blood cells, molecules & diseases 2005;35(2):111-5.
2005: Magali Terme; Christophe Borg; françois guilhot; Carole Masurier; Caroline Flament; Erwin F Wagner; Sophie Caillat-Zucman; Alain BERNHEIM; Ali G Turhan; Anne Caignard; Laurence Zitvogel
BCR/ABL promotes dendritic cell-mediated natural killer cell activation.
Cancer research 2005;65(14):6409-17.
2005: Nathalie Chaput; Julien Taïeb; Fabrice André; Laurence Zitvogel
The potential of exosomes in immunotherapy.
Expert opinion on biological therapy 2005;5(6):737-47.
2005: Julien Taïeb; Nathalie Chaput; Laurence Zitvogel
Dendritic cell-derived exosomes as cell-free peptide-based vaccines.
Critical reviews in immunology 2005;25(3):215-23.
2004: Christophe Borg; Abdelali JALIL; Diego Laderach; Kouji Maruyama; Hiro Wakasugi; Sabine Charrier; Bernhard Ryffel; Alessandra Cambi; Carl G Figdor; William Vainchenker; Anne Galy; Anne Caignard; Laurence Zitvogel
NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.
Blood 2004;104(10):3267-75.
2004: Christophe Borg; Magali Terme; Julien Taïeb; Cédric Ménard; Caroline Flament; Caroline Robert; Koji Maruyama; Hiro Wakasugi; Eric Angevin; Kris Thielemans; Axel Le Cesne; Véronique Chung-Scott; Vladimir Lazar; Isabelle Tchou; Florent Crépineau; francois Lemoine; Jacky Bernard; Jonhantan A Fletcher; Ali G Turhan; Jean-Yves Blay; Alain Spatz; Jean-François Emile; Michael C Heinrich; Salaheddine Mécheri; Thomas Tursz; Laurence Zitvogel
Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects.
The Journal of clinical investigation 2004;114(3):379-88.
2004: Magali Terme; Elena Tomasello; Koji Maruyama; Florent Crépineau; Nathalie Chaput; Caroline Flament; Jean-Pierre Marolleau; Eric Angevin; Erwin F Wagner; Benoît Salomon; François A Lemonnier; Hiro Wakasugi; Marco COLONna; Eric Vivier; Laurence Zitvogel
IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(10):5957-66.
2004: J P J J Hegmans; Martin P L Bard; Annabrita Hemmes; Theo M Luider; Monique J Kleijmeer; Jan-Bas Prins; Laurence Zitvogel; Sjaak A Burgers; Henk C Hoogsteden; Bart N Lambrecht
Proteomic analysis of exosomes secreted by human mesothelioma cells.
The American journal of pathology 2004;164(5):1807-15.
2004: Mojgan Movassagh; Alain Spatz; Jean Davoust; Serge Lebecque; Pedro Romero; Mikaël Pittet; Donata Rimoldi; Danielle Liénard; Oliver Gugerli; Laurent Ferradini; Caroline Robert; Marie-Françoise Avril; Laurence Zitvogel; Eric Angevin
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Cancer research 2004;64(6):2192-8.
2004: Julien Taïeb; Koji Maruyama; Christophe Borg; Magali Terme; Laurence Zitvogel
Imatinib mesylate impairs Flt3L-mediated dendritic cell expansion and antitumor effects in vivo.
Blood 2004;103(5):1966-7; author reply 1967.
2004: Nathalie Chaput; Julien Taïeb; Noël Emile Célestin Schartz; Fabrice André; Eric Angevin; Laurence Zitvogel
Exosome-based immunotherapy.
Cancer immunology, immunotherapy : CII 2004;53(3):234-9.
2004: Nathalie Chaput; Noël Emile Célestin Schartz; Fabrice André; Julien Taïeb; Sophie Novault; Pierre Bonnaventure; Nathalie Aubert; Jacky Bernard; François Lemonnier; Miriam Merad; Gosse J Adema; Malcolm Adams; Maria Ferrantini; Antoine F Carpentier; Bernard Escudier; Thomas Tursz; Eric Angevin; Laurence Zitvogel
Exosomes as potent cell-free peptide-based vaccine. II. Exosomes in CpG adjuvants efficiently prime naive Tc1 lymphocytes leading to tumor rejection.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2137-46.
2004: Fabrice André; Nathalie Chaput; Noël Emile Célestin Schartz; Caroline Flament; Nathalie Aubert; Jacky Bernard; François Lemonnier; Graça Raposo; Bernard Escudier; Di-Hwei Hsu; Thomas Tursz; Sebastian Amigorena; Eric Angevin; Laurence Zitvogel
Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2126-36.
2004: Fabrice Andre; Bernard Escudier; Eric Angevin; Thomas Tursz; Laurence Zitvogel
Exosomes for cancer immunotherapy.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15 Suppl 4():iv141-4.
2004: Laurence Zitvogel; Noelia Casares; Marie O Péquignot; Nathalie Chaput; Matthew L Albert; Guido Kroemer
Immune response against dying tumor cells.
Advances in immunology 2004;84():131-79.
2003: Di-Hwei Hsu; Pedro Paz; Gilbert Villaflor; Alberto Rivas; Anita Mehta-Damani; Eric Angevin; Laurence Zitvogel; Jean-Bernard Le Pecq
Exosomes as a tumor vaccine: enhancing potency through direct loading of antigenic peptides.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2003;26(5):440-50.
2003: Christophe Borg; Julien Taieb; Magali Terme; Kuji Maruyama; Caroline Flament; Eric Angevin; Laurence Zitvogel
[NK cell-based immunotherapy: new prospects and involvement of dendritic cells].
Bulletin du cancer 2003;90(8-9):699-705.
2003: Nathalie Chaput; Fabrice Andre; Noël Emile Célestin Schartz; Caroline Flament; Eric Angevin; Bernard Escudier; Laurence Zitvogel
[Exosomes and anti-tumour immunotherapy].
Bulletin du cancer 2003;90(8-9):695-8.
2003: Nathalie Chaput; Noël Emile Célestin Schartz; Fabrice Andre; Laurence Zitvogel
Exosomes for immunotherapy of cancer.
Advances in experimental medicine and biology 2003;532():215-21.
2002: Fabrice André; Noël Emile Célestin Schartz; Nathalie Chaput; Caroline Flament; Graça Raposo; Sebastian Amigorena; Eric Angevin; Laurence Zitvogel
Tumor-derived exosomes: a new source of tumor rejection antigens.
Vaccine 2002;20 Suppl 4():A28-31.
2002: Dominique Valteau-Couanet; Christophe Leboulaire; Kim Maincent; Muriel Tournier; Olivier Hartmann; Jean Bénard; Françoise Beaujean; Catherine Boccaccio; Laurence Zitvogel; Eric Angevin
Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients.
Blood 2002;100(7):2554-61.
2002: Noël Emile Célestin Schartz; Nathalie Chaput; Fabrice André; Laurence Zitvogel
From the antigen-presenting cell to the antigen-presenting vesicle: the exosomes.
Current opinion in molecular therapeutics 2002;4(4):372-81.
2002: Clotilde Théry; Laurence Zitvogel; Sebastian Amigorena
Exosomes: composition, biogenesis and function.
Nature reviews. Immunology 2002;2(8):569-79.
2002: Fabrice Andre; Noël Emile Célestin Schartz; Mojgan Movassagh; Caroline Flament; Patricia Pautier; Philippe Morice; Christophe Pomel; Catherine Lhomme; Bernard Escudier; Thierry Le Chevalier; Thomas Tursz; Sebastian Amigorena; Graça Raposo; Eric Angevin; Laurence Zitvogel
Malignant effusions and immunogenic tumour-derived exosomes.
Lancet 2002;360(9329):295-305.
2002: Laurence Zitvogel
Dendritic and natural killer cells cooperate in the control/switch of innate immunity.
The Journal of experimental medicine 2002;195(3):F9-14.
2002: Nadine C Fernandez; Caroline Flament; Florent Crépineau; Eric Angevin; Eric Vivier; Laurence Zitvogel
Dendritic cells (DC) promote natural killer (NK) cell functions: dynamics of the human DC/NK cell cross talk.
European cytokine network 2002;13(1):17-27.
2002: Pierre Guermonprez; Jenny Valladeau; Laurence Zitvogel; Clotilde Théry; Sebastian Amigorena
Antigen presentation and T cell stimulation by dendritic cells.
Annual review of immunology 2002;20():621-67.
2001: Y Ikarashi; R Mikami; A Bendelac; Magali Terme; Nathalie Chaput; M Terada; Thomas Tursz; Eric Angevin; François A Lemonnier; Hiro Wakasugi; Laurence Zitvogel
Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: critical role for B7 in CD1d-dependent NKT cell interferon gamma production.
The Journal of experimental medicine 2001;194(8):1179-86.
2001: J Wolfers; A Lozier; Graça Raposo; Armelle Regnault; Clotilde Théry; Carole Masurier; Caroline Flament; S Pouzieux; Florence Faure; Thomas Tursz; Eric Angevin; Sebastian Amigorena; Laurence Zitvogel
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.
Nature medicine 2001;7(3):297-303.
2001: Fabrice Andre; M Andersen; J Wolfers; A Lozier; Graça Raposo; V Serra; C Ruegg; Caroline Flament; Eric Angevin; Sebastian Amigorena; Laurence Zitvogel
Exosomes in cancer immunotherapy: preclinical data.
Advances in experimental medicine and biology 2001;495():349-54.
2000: Miriam Merad; Eric Angevin; J Wolfers; Caroline Flament; I Lorenzi; Frédéric Triebel; Bernard Escudier; Laurence Zitvogel
Generation of monocyte-derived dendritic cells from patients with renal cell cancer: modulation of their functional properties after therapy with biological response modifiers (IFN-alpha plus IL-2 and IL-12).
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(3):369-78.
2000: Laurence Zitvogel; Eric Angevin; Thomas Tursz
Dendritic cell-based immunotherapy of cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11 Suppl 3():199-205.
2000: Eric Angevin; Fabrice André; Laurence Zitvogel
[Antitumor cellular immunotherapy: the breakthrough of dendritic cells].
Bulletin du cancer 2000;87(1):107-15.
1999: Clotilde Théry; Armelle Regnault; Jérôme Garin; J Wolfers; Laurence Zitvogel; Paola Ricciardi-Castagnoli; Graça Raposo; Sebastian Amigorena
Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.
The Journal of cell biology 1999;147(3):599-610.
1999: Laurence Zitvogel; Nadine C Fernandez; A Lozier; J Wolfers; Armelle Regnault; Graça Raposo; Sebastian Amigorena
Dendritic cells or their exosomes are effective biotherapies of cancer.
European journal of cancer (Oxford, England : 1990) 1999;35 Suppl 3():S36-8.
1999: Nadine C Fernandez; A Lozier; Caroline Flament; Paola Ricciardi-Castagnoli; Dominique Bellet; M Suter; Michel Perricaudet; Thomas Tursz; E Maraskovsky; Laurence Zitvogel
Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.
Nature medicine 1999;5(4):405-11.
1998: Laurence Zitvogel; Armelle Regnault; A Lozier; J Wolfers; Caroline Flament; Danièle Tenza; Paola Ricciardi-Castagnoli; Graça Raposo; Sebastian Amigorena
Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes.
Nature medicine 1998;4(5):594-600.
1997: Hanne Gahéry-Ségard; Valérie Molinier-Frenkel; C Le Boulaire; Patrick Saulnier; Paule Opolon; Renée Lengagne; E Gautier; A Le Cesne; Laurence Zitvogel; Alain Venet; C Schatz; M Courtney; T Le Chevalier; Thomas Tursz; Jean-Gérard Guillet; Françoise Farace
Phase I trial of recombinant adenovirus gene transfer in lung cancer. Longitudinal study of the immune responses to transgene and viral products.
The Journal of clinical investigation 1997;100(9):2218-26.