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Kimberly Brown

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Kimberly K Brown; Sandra A Heitmeyer; Erin B Hookfin; Lily Hsieh; Maria Buchalova; Yetunde O Taiwo; Michael J Janusz
P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis.
Jennifer A Maier; Todd A Brugel; Mark Sabat; Adam Golebiowski; Matthew J Laufersweiler; John C VanRens; Corey Hopkins; Biswanath De; Lily C Hsieh; Kimberly K Brown; Vijayasurian Easwaran; Michael J Janusz
Development of N-4,6-pyrimidine-N-alkyl-N'-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase.
Jennifer A Maier; Todd A Brugel; Michael P Clark; Mark Sabat; Adam Golebiowski; Roger G Bookland; Matthew J Laufersweiler; Steven K Laughlin; John C VanRens; Biswanath De; Lily C Hsieh; Kimberly K Brown; Karen Juergens; Richard L Walter; Michael J Janusz
Development of N-2,4-pyrimidine-N-phenyl-N'-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 2.

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All Publications

2008: Kimberly K Brown; Sandra A Heitmeyer; Erin B Hookfin; Lily Hsieh; Maria Buchalova; Yetunde O Taiwo; Michael J Janusz
P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis.
Journal of inflammation (London, England) 2008;5():22.
2006: Jennifer A Maier; Todd A Brugel; Mark Sabat; Adam Golebiowski; Matthew J Laufersweiler; John C VanRens; Corey Hopkins; Biswanath De; Lily C Hsieh; Kimberly K Brown; Vijayasurian Easwaran; Michael J Janusz
Development of N-4,6-pyrimidine-N-alkyl-N'-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase.
Bioorganic & medicinal chemistry letters 2006;16(14):3646-50.
2006: Jennifer A Maier; Todd A Brugel; Michael P Clark; Mark Sabat; Adam Golebiowski; Roger G Bookland; Matthew J Laufersweiler; Steven K Laughlin; John C VanRens; Biswanath De; Lily C Hsieh; Kimberly K Brown; Karen Juergens; Richard L Walter; Michael J Janusz
Development of N-2,4-pyrimidine-N-phenyl-N'-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 2.
Bioorganic & medicinal chemistry letters 2006;16(13):3514-8.
2006: Michael J Janusz; EB Hookfin; Kimberly K Brown; Lily C Hsieh; Sandra A Heitmeyer; Yetunde O Taiwo; Michael G Natchus; S Pikul; NG Almstead; Biswanath De; Sean X Peng; Timothy R Baker; V Patel
Comparison of the pharmacology of hydroxamate- and carboxylate-based matrix metalloproteinase inhibitors (MMPIs) for the treatment of osteoarthritis.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2006;55(2):60-5.
2004: Michael J Janusz; Christopher B Little; L E King; EB Hookfin; Kimberly K Brown; Sandra A Heitmeyer; Bruce Caterson; A R Poole; Yetunde O Taiwo
Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2004;12(9):720-8.
2004: Matthew J Laufersweiler; Todd A Brugel; Michael P Clark; Adam Golebiowski; Roger G Bookland; Steven K Laughlin; Mark Sabat; Jennifer A Townes; John C VanRens; Biswanath De; Lily C Hsieh; Sandra A Heitmeyer; Karen Juergens; Kimberly K Brown; Marlene Mekel; Richard L Walter; Michael J Janusz
The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones.
Bioorganic & medicinal chemistry letters 2004;14(16):4267-72.
2004: Michael P Clark; Steven K Laughlin; Matthew J Laufersweiler; Roger G Bookland; Todd A Brugel; Adam Golebiowski; Mark Sabat; Jennifer A Townes; John C VanRens; Jane F Djung; Michael G Natchus; Biswanath De; Lily C Hsieh; Susan C Xu; Richard L Walter; Marlene Mekel; Sandra A Heitmeyer; Kimberly K Brown; Karen Juergens; Yetunde O Taiwo; Michael J Janusz
Development of orally bioavailable bicyclic pyrazolones as inhibitors of tumor necrosis factor-alpha production.
Journal of medicinal chemistry 2004;47(11):2724-7.
2002: Michael J Janusz; A M Bendele; Kimberly K Brown; Yetunde O Taiwo; L Hsieh; Sandra A Heitmeyer
Induction of osteoarthritis in the rat by surgical tear of the meniscus: Inhibition of joint damage by a matrix metalloproteinase inhibitor.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(10):785-91.
2001: Michael J Janusz; EB Hookfin; Sandra A Heitmeyer; J F Woessner; A J Freemont; J A Hoyland; Kimberly K Brown; Lily C Hsieh; NG Almstead; Biswanath De; Michael G Natchus; S Pikul; Yetunde O Taiwo
Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(8):751-60.