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Fabien Zoulim

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Baptiste Jammart; Maud Michelet; Romain Parent; Eve-Isabelle Pécheur; Fabien Zoulim; Birke Bartosch; David Durantel
Very-Low-Density Lipoprotein (VLDL)-Producing and Hepatitis C Virus-Replicating HepG2 Cells Secrete No More Lipoviroparticles than VLDL-Deficient Huh7.5 Cells.
Roeland Zoutendijk; Thomas Berg; Ashley Brown; Maria Buti; Katja Deterding; Massimo Fasano; Bettina E Hansen; Wolf Peter Hofmann; Harry L A Janssen; David J Mutimer; Joerg Petersen; Jurrien G P Reijnders; Milan J Sonneveld; Heiner Wedemeyer; Fabien Zoulim
Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis.
FADI SAADE; Fabien Zoulim; Thierry Buronfosse; Michèle Chevallier; Sylviane Guerret; Catherine Jamard; Pierre Pradat; Lucyna Cova
In vivo infectivity of liver extracts after resolution of hepadnaviral infection following therapy associating DNA vaccine and cytokine genes.

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2013: Baptiste Jammart; Maud Michelet; Romain Parent; Eve-Isabelle Pécheur; Fabien Zoulim; Birke Bartosch; David Durantel
Very-Low-Density Lipoprotein (VLDL)-Producing and Hepatitis C Virus-Replicating HepG2 Cells Secrete No More Lipoviroparticles than VLDL-Deficient Huh7.5 Cells.
Journal of virology 2013;87(9):5065-80.
2013: Roeland Zoutendijk; Thomas Berg; Ashley Brown; Maria Buti; Katja Deterding; Massimo Fasano; Bettina E Hansen; Wolf Peter Hofmann; Harry L A Janssen; David J Mutimer; Joerg Petersen; Jurrien G P Reijnders; Milan J Sonneveld; Heiner Wedemeyer; Fabien Zoulim
Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis.
Gut 2013;62(5):760-5.
2013: FADI SAADE; Fabien Zoulim; Thierry Buronfosse; Michèle Chevallier; Sylviane Guerret; Catherine Jamard; Pierre Pradat; Lucyna Cova
In vivo infectivity of liver extracts after resolution of hepadnaviral infection following therapy associating DNA vaccine and cytokine genes.
Journal of viral hepatitis 2013;20(4):e56-65.
2013: Sarah Maylin; François SIMON; Fabien Zoulim; Georges Bagnard; Anders Boyd; Constance Delaugerre; Pierre-Marie Girard; Martine Lapalus; Fabien Lavocat; Patrick Marcellin; Michèle Martinot-Peignoux; Karine Lacombe
Quantification of hepatitis B e antigen between Elecsys HBeAg and Architect HBeAg assays among patients infected with hepatitis B virus.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2013;56(4):306-11.
2013: Fabien Zoulim; Stephen Locarnini
Optimal management of chronic hepatitis B patients with treatment failure and antiviral drug resistance.
Liver international : official journal of the International Association for the Study of the Liver 2013;33 Suppl 1():116-24.
2013: Juliette Hayer; Fanny Jadeau; Alan Kay; Fabien Zoulim; Gilbert Deléage; Christophe Combet
HBVdb: a knowledge database for Hepatitis B Virus.
Nucleic acids research 2013;41(Database issue):D566-70.
2012: Pieter C van Breugel; Fabien Zoulim; Adrien Decorsière; Olivier Hantz; Henrik Mueller; Eva I Robert; Michel Strubin
Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates.
Hepatology (Baltimore, Md.) 2012;56(6):2116-24.
2012: Ghada Khawaja; Alain Luxembourg; Fabien Zoulim; Fabien Abdul; Thierry Buronfosse; Claire F Evans; Sylviane Guerret; Drew Hannaman; Daniel Hartmann; Catherine Jamard; Lucyna Cova
In vivo electroporation improves therapeutic potency of a DNA vaccine targeting hepadnaviral proteins.
Virology 2012;433(1):192-202.
2012: Fabien Zoulim
Are novel combination therapies needed for chronic hepatitis B?
Antiviral research 2012;96(2):256-9.
2012: Vincent Leroy; Georges-Philippe Pageaux; Alexandre Pariente; Stanislas Pol; Lawrence Serfaty; Fabien Zoulim; Marc Bourlière; Jean-Pierre Bronowicki; Patrick Delasalle
Protease inhibitor-based triple therapy in chronic hepatitis C: guidelines by the French Association for the Study of the Liver.
Liver international : official journal of the International Association for the Study of the Liver 2012;32(10):1477-92.
2012: Jeremie Martinet; Joel Plumas; Marie-Jeanne Richard; Fabien Zoulim; Tania Dufeu-Duchesne; Sylvie Larrat; Vincent Leroy; Caroline Aspord
Plasmacytoid dendritic cells induce efficient stimulation of antiviral immunity in the context of chronic hepatitis B virus infection.
Hepatology (Baltimore, Md.) 2012;56(5):1706-18.
2012: David Durantel; Fabien Zoulim
Interplay between hepatitis B virus and TLR2-mediated innate immune responses: can restoration of TLR2 functions be a new therapeutic option?
Journal of hepatology 2012;57(3):486-9.
2012: Caroline Scholtes; Claude Wolf; Fabien Zoulim; Patrice André; Ralf Bartenschlager; Martine Carreras; Aurélie Guironnet-Paquet; Lydie Humbert; Vincent Lotteau; Laure Perrin-Cocon; Dominique Rainteau; Christophe Ramière; Olivier Diaz
High plasma level of nucleocapsid-free envelope glycoprotein-positive lipoproteins in hepatitis C patients.
Hepatology (Baltimore, Md.) 2012;56(1):39-48.
2012: Nora Martel; Mary-Anne Trabaud; Christian Trepo; Fabien Zoulim; Laurent Cotte; Selma A Gomes; Alan Kay
Probable corticosteroid-induced reactivation of latent hepatitis B virus infection in an HIV-positive patient involving immune escape.
The Journal of infectious diseases 2012;205(11):1757-61.
2012: Caroline Scholtes; Mary-Anne Trabaud; Fabien Zoulim; Vinca Icard; Christophe Ramière; Majid Amiri; Patrice André; Philippe Chevallier-Queyron; Paul Dény
Standardized one-step real-time reverse transcription-PCR assay for universal detection and quantification of hepatitis delta virus from clinical samples in the presence of a heterologous internal-control RNA.
Journal of clinical microbiology 2012;50(6):2126-8.
2012: Gaëtan Billioud; Romain Parent; Christian Pichoud; Fabien Zoulim
Decreased infectivity of nucleoside analogs-resistant hepatitis B virus mutants.
Journal of hepatology 2012;56(6):1269-75.
2012: Sarah Maylin; Patrick Miailhes; Fabien Zoulim; Caroline Lascoux-Combe; Ludovic Lassel; Fabien Lavocat; Anders Boyd; Constance Delaugerre; Pierre-Marie Girard; joel gozlan; Karine Lacombe
Kinetics of hepatitis B surface and envelope antigen and prediction of treatment response to tenofovir in antiretroviral-experienced HIV-hepatitis B virus-infected patients.
AIDS (London, England) 2012;26(8):939-49.
2012: David L Thomas; Fabien Zoulim
New challenges in viral hepatitis.
Gut 2012;61 Suppl 1():i1-5.
2012: Robert Gish; Ji-Dong Jia; Stephen Locarnini; Fabien Zoulim
Selection of chronic hepatitis B therapy with high barrier to resistance.
The Lancet infectious diseases 2012;12(4):341-53.
2012: Frédéric Le Gal; Fabien Zoulim; Filiz Akyüz; Selim Badur; Ségolène Brichler; Elyanne Gault; Emmanuel Gordien; Nasser Al Hawajri; Sabahattin Kaymakoglu; Paul Dény
Current hepatitis delta virus type 1 (HDV1) infections in central and eastern Turkey indicate a wide genetic diversity that is probably linked to different HDV1 origins.
Archives of virology 2012;157(4):647-59.
2012: Ghada Khawaja; Alain Luxembourg; Fabien Zoulim; Thierry Buronfosse; Claire Evans; Sylviane Guerret; Drew Hannaman; Daniel Hartmann; Catherine Jamard; Lucyna Cova
Enhanced magnitude and breadth of neutralizing humoral response to a DNA vaccine targeting the DHBV envelope protein delivered by in vivo electroporation.
Virology 2012;425(1):61-9.
2012: Fabien Zoulim; William S Mason
Reasons to consider earlier treatment of chronic HBV infections.
Gut 2012;61(3):333-6.
2012: Jorg Petersen; Vlad Ratziu; Christoph Sarrazin; Jan Schollmeyer; Martina Sterneck; Heiner Wedemeyer; Fabien Zoulim; Maria Buti; Harry L A Janssen; Pietro Lampertico; Marc Lutgehetmann; Thomas Berg; Ashley Brown; Peter Buggisch
Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: an international multicenter cohort study.
Journal of hepatology 2012;56(3):520-6.
2012: Sarah Maylin; François Simon; Fabien Zoulim; Fabien Lavocat; Anders Boyd; Constance Delaugerre; Pierre-Marie Girard; Karine Lacombe
Comparison between Elecsys HBsAg II and architect HBsAg QT assays for quantification of hepatitis B surface antigen among patients coinfected with HIV and hepatitis B virus.
Clinical and vaccine immunology : CVI 2012;19(2):242-8.
2012: Fabien Abdul; Thierry Buronfosse; Michael Kann; Benedicte Ndeboko; Peter E Nielsen; Fabien Zoulim; Lucyna Cova
Potent inhibition of late stages of hepadnavirus replication by a modified cell penetrating peptide.
PloS one 2012;7(11):e48721.
2012: Bouchra Kitab; Christian Trepo; Fabien Zoulim; Rajaa Afifi; Hanane Salih Alj; Mustapha Benazzouz; Isabelle Chemin; Abdellah Essaid El Feydi; Wafaa Essamri; Sayeh Ezzikouri; Soumaya Benjelloun
Variability in the precore and core promoter regions of HBV strains in Morocco: characterization and impact on liver disease progression.
PloS one 2012;7(8):e42891.
2012: Fabien Zoulim; Stephen Locarnini
Management of treatment failure in chronic hepatitis B.
Journal of hepatology 2012;56 Suppl 1():S112-22.
2011: Stefan Zeuzem; Fabien Zoulim; Peter Angus; Keikawus Arastéh; Tarik Asselah; Jean-Pierre Bronowicki; Ed Gane; Carla Haefner; Markus Heim; George Kukolj; Dominique Larrey; Ansgar Lohse; Beat Müllhaupt; Gerhard Nehmiz; Stanislas Pol; Stuart Roberts; Marcus Schuchmann; Jerry O Stern; Jean-Pierre Zarski; Wulf Otto Boecher
Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection.
Gastroenterology 2011;141(6):2047-55; quiz e14.
2011: Gaëtan Billioud; Johan Neyts; Christian Pichoud; Gerhard Puerstinger; Fabien Zoulim
The main hepatitis B virus (HBV) mutants resistant to nucleoside analogs are susceptible in vitro to non-nucleoside inhibitors of HBV replication.
Antiviral research 2011;92(2):271-6.
2011: Julie Lucifora; Michel Strubin; Fabien Zoulim; Silke Arzberger; Laura Belloni; David Durantel; Olivier Hantz; Massimo Levrero; Ulrike Protzer
Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection.
Journal of hepatology 2011;55(5):996-1003.
2011: Si Nafa Si Ahmed; Heiner Wedemeyer; Roeland Zoutendijk; François Bailly; Maria Buti; Claire Cruiziat; Katja Deterding; Jérôme Dumortier; Rafael Esteban; Harry L Janssen; Vincent Mallet; Pierre Pradat; Fabien Zoulim
Efficacy and tolerance of a combination of tenofovir disoproxil fumarate plus emtricitabine in patients with chronic hepatitis B: a European multicenter study.
Antiviral research 2011;92(1):90-5.
2011: Karine Barral; Bruno Canard; Céline Durafour; Johan Neyts; Nadine Payrot; Stéphane Priet; Loic Roux; Clément Weck; Fabien Zoulim; Jan Balzarini; Karine Alvarez
Acyclic nucleoside thiophosphonates as potent inhibitors of HIV and HBV replication.
European journal of medicinal chemistry 2011;46(9):4281-8.
2011: Roeland Zoutendijk; Thomas Berg; Ashley Brown; Maria Buti; Katja Deterding; Bettina E Hansen; Wolf Peter Hofmann; Harry L A Janssen; Marc Luetgehetmann; David Mutimer; Ye Oo; Jörg Petersen; Pierre Pradat; Jurriën G P Reijnders; Teresa Santantonio; Florian van Bommel; Heiner Wedemeyer; Fabien Zoulim
Entecavir treatment for chronic hepatitis B: adaptation is not needed for the majority of naïve patients with a partial virological response.
Hepatology (Baltimore, Md.) 2011;54(2):443-51.
2011: Fabien Zoulim
Hepatitis: Treatment failure in chronic hepatitis B.
Nature reviews. Gastroenterology & hepatology 2011;8(7):366-7.
2011: Katja Deterding; A Guerrero; H Janssen; J Kirschner; L Naesens; J Neyts; J Reijnders; M Buti; Fabien Zoulim; Heiner Wedemeyer
Adefovir serum levels do not differ between responders and nonresponders.
Journal of viral hepatitis 2011;18(7):e175-8.
2011: Bouchra Kitab; Khadija Rebbani; Hanane Salih Alj; Christian Trepo; Fabien Zoulim; Ikram Brahim; Isabelle Chemin; Younes Cherradi; Omar Derdabi; Abdellah Essaid El Feydi; Sayeh Ezzikouri; Rajaa Afifi; Mustapha Benazzouz; Soumaya Benjelloun
Hepatitis B genotypes/subgenotypes and MHR variants among Moroccan chronic carriers.
The Journal of infection 2011;63(1):66-75.
2011: Ruchi Shukla; Maha Siouda; Massimo Tommasino; Jiping Yue; Fabien Zoulim; Tarik Gheit; Olivier Hantz; Vladimir Krutovskikh; Philippe Merle; Bakary S Sylla
Proinflammatory cytokine TNF-α increases the stability of hepatitis B virus X protein through NF-κB signaling.
Carcinogenesis 2011;32(7):978-85.
2011: Susan Obeid; Svetlana S Printsevskaya; Evgenia N Olsufyeva; Kai Dallmeier; David Durantel; Fabien Zoulim; Maria N Preobrazhenskaya; Johan Neyts; Jan Paeshuyse
Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics.
The Journal of antimicrobial chemotherapy 2011;66(6):1287-94.
2011: Yan Liu; C Wang; Y Zhong; X Li; J Dai; X Ren; Z Xu; L Li; Z Yao; D Ji; L Wang; L Zhang; V W-S Wong; Fabien Zoulim; D Xu
Genotypic resistance profile of hepatitis B virus (HBV) in a large cohort of nucleos(t)ide analogue-experienced Chinese patients with chronic HBV infection.
Journal of viral hepatitis 2011;18(4):e29-39.
2011: Marie-Pierre Lambert; Anupam Paliwal; Thomas Vaissière; Isabelle Chemin; Fabien Zoulim; Massimo Tommasino; Pierre Hainaut; Bakary Sylla; Jean-Yves Scoazec; Jörg Tost; Zdenko Herceg
Aberrant DNA methylation distinguishes hepatocellular carcinoma associated with HBV and HCV infection and alcohol intake.
Journal of hepatology 2011;54(4):705-15.
2011: Laurent Cotte; Thomas Bénet; Claire Billioud; Patrick Miailhes; Jean-Yves Scoazec; Tristan Ferry; Corinne Brochier; André Boibieux; Philippe Vanhems; Michèle Chevallier; Fabien Zoulim
The role of nucleoside and nucleotide analogues in nodular regenerative hyperplasia in HIV-infected patients: a case control study.
Journal of hepatology 2011;54(3):489-96.
2011: Zhihui Xu; Xiaoqiang Ren; Yan Liu; Xiaodong Li; Siyu Bai; Yanwei Zhong; Lin Wang; Panyong Mao; Huifen Wang; Shaojie Xin; Vincent Wai-Sun Wong; Henry Lik-Yuen Chan; Fabien Zoulim; Dongping Xu
Association of hepatitis B virus mutations in basal core promoter and precore regions with severity of liver disease: an investigation of 793 Chinese patients with mild and severe chronic hepatitis B and acute-on-chronic liver failure.
Journal of gastroenterology 2011;46(3):391-400.
2011: Sarah Beseme Nambotin; Lydie Lefrancois; Xavier Sainsily; Pascale Berthillon; Miran Kim; Jack R Wands; Michele Chevallier; Pierre Jalinot; Jean-Yves Scoazec; Christian Trepo; Fabien Zoulim; Philippe Merle
Pharmacological inhibition of Frizzled-7 displays anti-tumor properties in hepatocellular carcinoma.
Journal of hepatology 2011;54(2):288-99.
2011: Isabelle E Vincent; Claudia Zannetti; Fabien Zoulim; Pierre Hainaut; Uzma A Hasan; Julie Lucifora; Helene Norder; Ulrike Protzer; Massimo Tommasino; Christian Trépo; Isabelle Chemin
Hepatitis B virus impairs TLR9 expression and function in plasmacytoid dendritic cells.
PloS one 2011;6(10):e26315.
2011: Fabien Zoulim
Hepatitis B virus resistance to antiviral drugs: where are we going?
Liver international : official journal of the International Association for the Study of the Liver 2011;31 Suppl 1():111-6.
2011: Patrick Miailhes; Pierre Pradat; Michèle Chevallier; K Lacombe; François Bailly; Laurent Cotte; Mary-Anne Trabaud; A Boibieux; J Bottero; Christian Trepo; Fabien Zoulim
Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
Journal of viral hepatitis 2011;18(1):61-9.
2010: X Ren; Z Xu; Y Liu; X Li; S Bai; N Ding; Y Zhong; L Wang; P Mao; Fabien Zoulim; D Xu
Hepatitis B virus genotype and basal core promoter/precore mutations are associated with hepatitis B-related acute-on-chronic liver failure without pre-existing liver cirrhosis.
Journal of viral hepatitis 2010;17(12):887-95.
2010: Ndiémé Ndongo; Pascale Berthillon; Pierre Pradat; Claude Vieux; Isabelle Bordes; Françoise Berby; Marianne Maynard; Fabien Zoulim; Christian Trépo; Marie-Anne Petit
Association of anti-E1E2 antibodies with spontaneous recovery or sustained viral response to therapy in patients infected with hepatitis C virus.
Hepatology (Baltimore, Md.) 2010;52(5):1531-42.
2010: Marie Gauthier; Bertrand Bonnaud; Maud Arsac; Fabien Lavocat; Jérôme Maisetti; Alan Campbell Kay; François Simon; Fabien Zoulim; Guy Vernet
Microarray for hepatitis B virus genotyping and detection of 994 mutations along the genome.
Journal of clinical microbiology 2010;48(11):4207-15.
2010: Thomas Berg; Patrick Marcellin; Fabien Zoulim; Bernd Moller; Huy Trinh; Sing Chan; Emilio Suarez; Fabien Lavocat; Andrea Snow-Lampart; David Frederick; Jeff Sorbel; Katyna Borroto-Esoda; David Oldach; Franck Rousseau
Tenofovir is effective alone or with emtricitabine in adefovir-treated patients with chronic-hepatitis B virus infection.
Gastroenterology 2010;139(4):1207-17.
2010: N Ben Slama; S N Si Ahmed; Fabien Zoulim
[HBsAg quantification: virological significance].
Gastroentérologie clinique et biologique 2010;34 Suppl 2():S112-8.
2010: Pushpinder Kaur; Anupam Paliwal; David Durantel; Pierre Hainaut; Jean-Yves Scoazec; Fabien Zoulim; Isabelle Chemin; Zdenko Herceg
DNA methylation of hepatitis B virus (HBV) genome associated with the development of hepatocellular carcinoma and occult HBV infection.
The Journal of infectious diseases 2010;202(5):700-4.
2010: Paul Dény; Fabien Zoulim
Hepatitis B virus: from diagnosis to treatment.
Pathologie-biologie 2010;58(4):245-53.
2010: Pierre Faurie; Christiane Broussolle; Fabien Zoulim; Christian Trepo; Pascal Sève
Sarcoidosis and hepatitis C: clinical description of 11 cases.
European journal of gastroenterology & hepatology 2010;22(8):967-72.
2010: Malika Ait-Goughoulte; Julie Lucifora; Fabien Zoulim; David Durantel
Innate antiviral immune responses to hepatitis B virus.
Viruses 2010;2(7):1394-410.
2010: Julie Lucifora; Isabelle E Vincent; Pascale Berthillon; Tatiana Dupinay; Maud Michelet; Ulrike Protzer; Fabien Zoulim; David Durantel; Christian Trepo; Isabelle Chemin
Hepatitis B virus replication in primary macaque hepatocytes: crossing the species barrier toward a new small primate model.
Hepatology (Baltimore, Md.) 2010;51(6):1954-60.
2010: Jurriën G P Reijnders; Katja Deterding; Jörg Petersen; Fabien Zoulim; Teresa Santantonio; Maria Buti; Florian van Bommel; Bettina E Hansen; Heiner Wedemeyer; Harry L A Janssen
Antiviral effect of entecavir in chronic hepatitis B: influence of prior exposure to nucleos(t)ide analogues.
Journal of hepatology 2010;52(4):493-500.
2010: Si Nafa Si Ahmed; Marie Ecochard; Fabien Zoulim
End points of therapy in chronic hepatitis B.
Expert review of gastroenterology & hepatology 2010;4(1):37-49.
2010: Yan Liu; Chunmei Wang; Yanwei Zhong; Li Chen; Xiaodong Li; Dong Ji; Huifen Wang; Shaojie Xin; Fabien Zoulim; Dongping Xu
Evolution and suppression of HBV strains with multidrug resistance to lamivudine, adefovir dipivoxil and entecavir in a patient with chronic hepatitis B.
Antiviral therapy 2010;15(8):1185-90.
2010: Stephen Locarnini; Fabien Zoulim
Molecular genetics of HBV infection.
Antiviral therapy 2010;15 Suppl 3():3-14.
2010: Karine Lacombe; Anders Christopher Boyd; Joel Gozlan; Fabien Lavocat; Pierre-Marie Girard; Fabien Zoulim
Drug-resistant and immune-escape HBV mutants in HIV-infected hosts.
Antiviral therapy 2010;15(3 Pt B):493-7.
2010: Julie Lucifora; David Durantel; Barbara Testoni; Olivier Hantz; Massimo Levrero; Fabien Zoulim
Control of hepatitis B virus replication by innate response of HepaRG cells.
Hepatology (Baltimore, Md.) 2010;51(1):63-72.
2009: David Durantel; Fabien Zoulim
Innate response to hepatitis B virus infection: observations challenging the concept of a stealth virus.
Hepatology (Baltimore, Md.) 2009;50(6):1692-5.
2009: Isabelle Chemin; Fabien Zoulim
Hepatitis B virus induced hepatocellular carcinoma.
Cancer letters 2009;286(1):52-9.
2009: Fabien Zoulim; Stephen Locarnini
Hepatitis B virus resistance to nucleos(t)ide analogues.
Gastroenterology 2009;137(5):1593-608.e1-2.
2009: Laurent Cotte; P Chevallier Queyron; I Schlienger; Mary-Anne Trabaud; C Brochier; P André; Fabien Zoulim
Sexually transmitted HCV infection and reinfection in HIV-infected homosexual men.
Gastroentérologie clinique et biologique 2009;33(10-11):977-80.
2009: Ndiémé Ndongo; Yassine Rechoum; Sylvie De Sequeira; Fabien Zoulim; Christian Trépo; E Drouet; Marie-Anne Petit
Inhibition of the binding of HCV serum particles to human hepatocytes by E1E2-specific D32.10 monoclonal antibody.
Journal of medical virology 2009;81(10):1726-33.
2009: Birke Bartosch; Robert Thimme; Hubert E Blum; Fabien Zoulim
Hepatitis C virus-induced hepatocarcinogenesis.
Journal of hepatology 2009;51(4):810-20.
2009: Christian Trépo; Fabien Zoulim
[Treatment of hepatitis B: new perspectives].
Gastroentérologie clinique et biologique 2009;33(8-9):811-7.
2009: Olivier Borgniet; Parviz Parvaz; Cécile Bouix; Philippe Chevallier; Christian Trépo; Patrice André; Fabien Zoulim
Clearance of serum HBsAg and anti-HBs seroconversion following antiviral therapy for chronic hepatitis B.
Journal of medical virology 2009;81(8):1336-42.
2009: Yan Liu; Chun-mei Wang; Jun Cheng; Zhao-ling Liang; Yan-wei Zhong; Xiao-qiang Ren; Zhi-hui Xu; Fabien Zoulim; Dong-ping Xu
Hepatitis B virus in tenofovir-naive Chinese patients with chronic hepatitis B contains no mutation of rtA194T conferring a reduced tenofovir susceptibility.
Chinese medical journal 2009;122(13):1585-6.
2009: Leen Delang; Jan Paeshuyse; Inge Vliegen; Pieter Leyssen; Susan Obeid; David Durantel; Fabien Zoulim; Anne Op de Beeck; Johan Neyts
Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development.
Hepatology (Baltimore, Md.) 2009;50(1):6-16.
2009: Catherine Chaubo; Arnaud Hot; Philippe Chevallier-Queyron; Jacques Ritter; Jean-Yves Scoazec; Fabien Zoulim; Alexandre Karamé; Maria Brunet; Jean-Louis Touraine; Emmanuel Morelon
Kidney transplant and cryptic hepatitis.
Lancet 2009;373(9680):2082.
2009: Si Nafa Si Ahmed; Fabien Zoulim
Pathobiology of HBV mutants and clinical impact for treatment monitoring.
Expert review of anti-infective therapy 2009;7(3):309-20.
2009: Adrian Covic; Daniel Abramowicz; Annette Bruchfeld; Geert Leroux-Roels; Didier Samuel; Wim van Biesen; Carmine Zoccali; Fabien Zoulim; Raymond Vanholder
Endorsement of the Kidney Disease Improving Global Outcomes (KDIGO) hepatitis C guidelines: a European Renal Best Practice (ERBP) position statement.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009;24(3):719-27.
2009: Fabien Zoulim; Parviz Parvaz; Patrick Marcellin; Jean-Pierre Zarski; Michel Beaugrand; Yves Benhamou; François Bailly; Marianne Maynard; Christian Trepo; Aldo Trylesinski; Françoise Monchecourt
Adefovir dipivoxil is effective for the treatment of cirrhotic patients with lamivudine failure.
Liver international : official journal of the International Association for the Study of the Liver 2009;29(3):420-6.
2009: Marlène Dreux; Viet Loan Dao Thi; Judith Fresquet; Maryse Guérin; Zélie Julia; Géraldine Verney; David Durantel; Fabien Zoulim; Dimitri Lavillette; François-Loïc Cosset; Birke Bartosch
Receptor complementation and mutagenesis reveal SR-BI as an essential HCV entry factor and functionally imply its intra- and extra-cellular domains.
PLoS pathogens 2009;5(2):e1000310.
2009: Yan Liu; Jian-Jun Zhao; Chun-mei Wang; Mian-yang Li; Ping Han; Lin Wang; Yong-qian Cheng; Fabien Zoulim; Xu Ma; Dong-ping Xu
Altered expression profiles of microRNAs in a stable hepatitis B virus-expressing cell line.
Chinese medical journal 2009;122(1):10-4.
2009: Teresa Santantonio; Massimo Fasano; Sandra Durantel; Luc Barraud; Manuela Heichen; Angela Guastadisegni; Giuseppe Pastore; Fabien Zoulim
Adefovir dipivoxil resistance patterns in patients with lamivudine-resistant chronic hepatitis B.
Antiviral therapy 2009;14(4):557-65.
2009: Isabelle E Vincent; Julie Lucifora; David Durantel; Olivier Hantz; Isabelle Chemin; Fabien Zoulim; Christian Trepo
Inhibitory effect of the combination of CpG-induced cytokines with lamivudine against hepatitis B virus replication in vitro.
Antiviral therapy 2009;14(1):131-5.
2009: Fabien Zoulim; David Durantel; Paul Deny
Management and prevention of drug resistance in chronic hepatitis B.
Liver international : official journal of the International Association for the Study of the Liver 2009;29 Suppl 1():108-15.
2009: Stéphanie Villet; Gaëtan Billioud; Christian Pichoud; Julie Lucifora; Olivier Hantz; Camille Sureau; Paul Dény; Fabien Zoulim
In vitro characterization of viral fitness of therapy-resistant hepatitis B variants.
Gastroenterology 2009;136(1):168-176.e2.
2008: Christine Alotte; Amaury Martin; Sergio A Caldarelli; Audrey Di Giorgio; Roger Condom; Fabien Zoulim; David Durantel; Olivier Hantz
Short peptide nucleic acids (PNA) inhibit hepatitis C virus internal ribosome entry site (IRES) dependent translation in vitro.
Antiviral research 2008;80(3):280-7.
2008: Fabien Zoulim; Sylvie Radenne; Christian Ducerf
Management of patients with decompensated hepatitis B virus associated [corrected] cirrhosis.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2008;14 Suppl 2():S1-7.
2008: Giovanni Raimondo; Jean-Pierre Allain; Maurizia R Brunetto; Marie Annick Buendia; Ding-Shinn Chen; Massimo Colombo; Antonio Craxì; Francesco Donato; Carlo Ferrari; Giovanni B Gaeta; Wolfram H Gerlich; Massimo Levrero; Stephen Locarnini; Thomas Michalak; Mario U Mondelli; Jean-Michel Pawlotsky; Teresa Pollicino; Daniele Prati; Massimo Puoti; Didier Samuel; Daniel Shouval; Antonina Smedile; Giovanni Squadrito; Christian Trépo; Erica Villa; Hans Will; Alessandro R Zanetti; Fabien Zoulim
Statements from the Taormina expert meeting on occult hepatitis B virus infection.
Journal of hepatology 2008;49(4):652-7.
2008: Séverine Margeridon; Sandra Carrouée-Durantel; Isabelle Chemin; Luc Barraud; Fabien Zoulim; Christian Trépo; Alan Campbell Kay
Rolling circle amplification, a powerful tool for genetic and functional studies of complete hepatitis B virus genomes from low-level infections and for directly probing covalently closed circular DNA.
Antimicrobial agents and chemotherapy 2008;52(9):3068-73.
2008: Vincent Soriano; Massimo Puoti; Marion Peters; Yves Benhamou; Mark S Sulkowski; Fabien Zoulim; Stefan Mauss; Jürgen Rockstroh
Care of HIV patients with chronic hepatitis B: updated recommendations from the HIV-Hepatitis B Virus International Panel.
AIDS (London, England) 2008;22(12):1399-410.
2008: Vincent Soriano; Alan S Perelson; Fabien Zoulim
Why are there different dynamics in the selection of drug resistance in HIV and hepatitis B and C viruses?
The Journal of antimicrobial chemotherapy 2008;62(1):1-4.
2008: Alexandre Thermet; Thierry Buronfosse; Bettina Werle-Lapostolle; Michèle Chevallier; Pierre Pradat; Christian Trepo; Fabien Zoulim; Lucyna Cova
DNA vaccination in combination or not with lamivudine treatment breaks humoral immune tolerance and enhances cccDNA clearance in the duck model of chronic hepatitis B virus infection.
The Journal of general virology 2008;89(Pt 5):1192-201.
2008: Stéphanie Villet; Christian Pichoud; Gaëtan Billioud; Luc Barraud; Sandra Durantel; Christian Trépo; Fabien Zoulim
Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure.
Journal of hepatology 2008;48(5):747-55.
2008: Jean-Michel Pawlotsky; Geoffrey Dusheiko; Angelos Hatzakis; Daryl Lau; George Lau; TSANYANG LIANG; Stephen Locarnini; Paul Martin; Douglas D Richman; Fabien Zoulim
Virologic monitoring of hepatitis B virus therapy in clinical trials and practice: recommendations for a standardized approach.
Gastroenterology 2008;134(2):405-15.
2008: Fabien Zoulim
[Current data on the treatment of chronic hepatitis B].
Presse médicale (Paris, France : 1983) 2008;37(2 Pt 2):287-93.
2008: Karine Lacombe; joel gozlan; Anders Christopher Boyd; Pierre-Yves Boelle; Philippe Bonnard; Jean-Michel Molina; Patrick Miailhes; Caroline Lascoux-Combe; Lawrence Serfaty; Fabien Zoulim; Pierre-Marie Girard
Comparison of the antiviral activity of adefovir and tenofovir on hepatitis B virus in HIV-HBV-coinfected patients.
Antiviral therapy 2008;13(5):705-13.
2008: Sandra Carrouée-Durantel; David Durantel; Bettina Werle-Lapostolle; Christian Pichoud; Lieve Naesens; Johan Neyts; Christian Trépo; Fabien Zoulim
Suboptimal response to adefovir dipivoxil therapy for chronic hepatitis B in nucleoside-naive patients is not due to pre-existing drug-resistant mutants.
Antiviral therapy 2008;13(3):381-8.
2008: Fabien Zoulim; Robert Perrillo
Hepatitis B: reflections on the current approach to antiviral therapy.
Journal of hepatology 2008;48 Suppl 1():S2-19.
2008: Helen Cooksley; Shilpa Chokshi; Yafit Maayan; Heiner Wedemeyer; Pietro Andreone; Richard Gilson; Thomas Warnes; Simona Paganin; Fabien Zoulim; David Frederick; Avidan U Neumann; Carol L Brosgart; Nikolai Naoumov
Hepatitis B virus e antigen loss during adefovir dipivoxil therapy is associated with enhanced virus-specific CD4+ T-cell reactivity.
Antimicrobial agents and chemotherapy 2008;52(1):312-20.
2007: David Durantel; Fabien Zoulim
Learning from HIV: how will drug resistance influence treatment strategies against hepatitis C?
Journal of HIV therapy 2007;12(4):88-91.
2007: Michael P Manns; Graham R Foster; Jürgen K Rockstroh; Stefan Zeuzem; Fabien Zoulim; Michael Houghton
The way forward in HCV treatment--finding the right path.
Nature reviews. Drug discovery 2007;6(12):991-1000.
2007: Vincent Thibault; Christian Pichoud; Carolyn Mullen; James Rhoads; Jane B Smith; Alain Bitbol; Sven Thamm; Fabien Zoulim
Characterization of a new sensitive PCR assay for quantification of viral DNA isolated from patients with hepatitis B virus infections.
Journal of clinical microbiology 2007;45(12):3948-53.
2007: Julie Sheldon; Belen Ramos; Javier Garcia-Samaniego; Pilar Rios; Angeline Bartholomeusz; Miriam Romero; Stephen Locarnini; Fabien Zoulim; Vincent Soriano
Selection of hepatitis B virus (HBV) vaccine escape mutants in HBV-infected and HBV/HIV-coinfected patients failing antiretroviral drugs with anti-HBV activity.
Journal of acquired immune deficiency syndromes (1999) 2007;46(3):279-82.
2007: Claire Fournier; Fabien Zoulim
Antiviral therapy of chronic hepatitis B: prevention of drug resistance.
Clinics in liver disease 2007;11(4):869-92, ix.
2007: Catalin Lazar; David Durantel; alina macovei; Nicole Zitzmann; Fabien Zoulim; Raymond A Dwek; Norica Branza-Nichita
Treatment of hepatitis B virus-infected cells with alpha-glucosidase inhibitors results in production of virions with altered molecular composition and infectivity.
Antiviral research 2007;76(1):30-7.
2007: Patrick Miailhes; Mary-Anne Trabaud; Pierre Pradat; Bertrand Lebouché; Michèle Chevallier; Philippe Chevallier; Fabien Zoulim; Christian Trepo
Impact of highly active antiretroviral therapy (HAART) on the natural history of hepatitis B virus (HBV) and HIV coinfection: relationship between prolonged efficacy of HAART and HBV surface and early antigen seroconversion.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;45(5):624-32.
2007: Ke Li; Fabien Zoulim; Christian Pichoud; Karen Kwei; Stéphanie Villet; Jack R Wands; Jisu Li; Shuping Tong
Critical role of the 36-nucleotide insertion in hepatitis B virus genotype G in core protein expression, genome replication, and virion secretion.
Journal of virology 2007;81(17):9202-15.
2007: Emmet B Keeffe; Stefan Zeuzem; Raymond S Koff; Douglas T Dieterich; Rafael Esteban-Mur; Edward Gane; Ira M Jacobson; Seng Gee Lim; Nikolai Naoumov; Patrick Marcellin; Teerha Piratvisuth; Fabien Zoulim
Report of an international workshop: Roadmap for management of patients receiving oral therapy for chronic hepatitis B.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2007;5(8):890-7.
2007: Saad Mrani; Isabelle Chemin; K Menouar; O Guillaud; Pierre Pradat; G Borghi; Mary-Anne Trabaud; Philippe Chevallier; Michèle Chevallier; Fabien Zoulim; Christian Trépo
Occult HBV infection may represent a major risk factor of non-response to antiviral therapy of chronic hepatitis C.
Journal of medical virology 2007;79(8):1075-81.
2007: Alan Campbell Kay; Fabien Zoulim
Hepatitis B virus genetic variability and evolution.
Virus research 2007;127(2):164-76.
2007: Anna S F Lok; Fabien Zoulim; Stephen Locarnini; Angeline Bartholomeusz; Marc G Ghany; Jean-Michel Pawlotsky; Yun-Fan Liaw; Masashi Mizokami; Carla Kuiken
Antiviral drug-resistant HBV: standardization of nomenclature and assays and recommendations for management.
Hepatology (Baltimore, Md.) 2007;46(1):254-65.
2007: Marie-Noëlle Brunelle; J Lucifora; J Neyts; Stéphanie Villet; A Holy; Christian Trepo; Fabien Zoulim
In vitro activity of 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]-pyrimidine against multidrug-resistant hepatitis B virus mutants.
Antimicrobial agents and chemotherapy 2007;51(6):2240-3.
2007: Fabien Zoulim
Emerging drugs for hepatitis B.
Expert opinion on emerging drugs 2007;12(2):199-217.
2007: Cynthia Chapel; Céline Garcia; Birke Bartosch; Philippe Roingeard; Nicole Zitzmann; François-Loïc Cosset; Jean Dubuisson; Raymond A Dwek; Christian Trépo; Fabien Zoulim; David Durantel
Reduction of the infectivity of hepatitis C virus pseudoparticles by incorporation of misfolded glycoproteins induced by glucosidase inhibitors.
The Journal of general virology 2007;88(Pt 4):1133-43.
2007: Stéphanie Villet; Aurélie Ollivet; Christian Pichoud; Luc Barraud; Jean-Pierre Villeneuve; Christian Trépo; Fabien Zoulim
Stepwise process for the development of entecavir resistance in a chronic hepatitis B virus infected patient.
Journal of hepatology 2007;46(3):531-8.
2007: David Durantel; Christine Alotte; Fabien Zoulim
Glucosidase inhibitors as antiviral agents for hepatitis B and C.
Current opinion in investigational drugs (London, England : 2000) 2007;8(2):125-9.
2007: Thierry Poynard; Rachel Morra; Philippe Halfon; Laurent Castera; Vlad Ratziu; Françoise Imbert-Bismut; Sylvie Naveau; Dominique Thabut; Didier Lebrec; Fabien Zoulim; Marc Bourliere; Patrice Cacoub; Djamila Messous; Mona Munteanu; Victor de Ledinghen
Meta-analyses of FibroTest diagnostic value in chronic liver disease.
BMC gastroenterology 2007;7():40.
2007: David Durantel; Fabien Zoulim
Going towards more relevant cell culture models to study the in vitro replication of serum-derived hepatitis C virus and virus/host cell interactions?
Journal of hepatology 2007;46(1):1-5.
2006: Fabien Zoulim
Hepatitis B virus resistance to entecavir in nucleoside naïve patients: Does it exist?
Hepatology (Baltimore, Md.) 2006;44(6):1404-7.
2006: Vanessa Escuret; Amaury Martin; David Durantel; Romain Parent; Olivier Hantz; Christian Trépo; Thierry Menguy; Emmanuel Bottius; Jerome Dardy; Jean Maral; Jean-Louis Escary; Fabien Zoulim
Novel alpha interferon (IFN-alpha) variant with improved inhibitory activity against hepatitis C virus genotype 1 replication compared to IFN-alpha2b therapy in a subgenomic replicon system.
Antimicrobial agents and chemotherapy 2006;50(12):3984-91.
2006: Karine Lacombe; Aurélie Ollivet; joel gozlan; Sandra Durantel; Nathalie Tran; Pierre-Marie Girard; Fabien Zoulim
A novel hepatitis B virus mutation with resistance to adefovir but not to tenofovir in an HIV-hepatitis B virus-co-infected patient.
AIDS (London, England) 2006;20(17):2229-31.
2006: Fabien Zoulim
New nucleic acid diagnostic tests in viral hepatitis.
Seminars in liver disease 2006;26(4):309-17.
2006: Ramamurthy Narayan; Thierry Buronfosse; Ursula Schultz; Philippe Chevallier-Gueyron; Sylviane Guerret; Michèle Chevallier; FADI SAADE; Benedicte Ndeboko; Christian Trepo; Fabien Zoulim; Lucyna Cova
Rise in gamma interferon expression during resolution of duck hepatitis B virus infection.
The Journal of general virology 2006;87(Pt 11):3225-32.
2006: Fabien Zoulim
[Definitions of resistance to analogue antiviral drugs in the treatment of chronic hepatitis B].
Gastroentérologie clinique et biologique 2006;30(10 Pt 2):3S9-11.
2006: Stéphanie Villet; Christian Pichoud; Jean-Pierre Villeneuve; Christian Trépo; Fabien Zoulim
Selection of a multiple drug-resistant hepatitis B virus strain in a liver-transplanted patient.
Gastroenterology 2006;131(4):1253-61.
2006: Olivier Diaz; François Delers; Marianne Maynard; Sylvie demignot; Fabien Zoulim; Jean CHAMBAZ; Christian Trépo; Vincent Lotteau; Patrice André
Preferential association of Hepatitis C virus with apolipoprotein B48-containing lipoproteins.
The Journal of general virology 2006;87(Pt 10):2983-91.
2006: Fabien Zoulim
Antiviral therapy of chronic hepatitis B.
Antiviral research 2006;71(2-3):206-15.
2006: Nathalie Tran; R Berne; R Chann; M Gauthier; D Martin; M-A Armand; Aurélie Ollivet; Chong Gee Teo; Samreen Ijaz; D Flichman; Maurizia Rossana Brunetto; Krzysztof Piotr Bielawski; Christian Pichoud; Fabien Zoulim; Guy Vernet
European multicenter evaluation of high-density DNA probe arrays for detection of hepatitis B virus resistance mutations and identification of genotypes.
Journal of clinical microbiology 2006;44(8):2792-800.
2006: Julie Sheldon; B Rodès; Fabien Zoulim; Angeline Bartholomeusz; Vincent Soriano
Mutations affecting the replication capacity of the hepatitis B virus.
Journal of viral hepatitis 2006;13(7):427-34.
2006: Karima Abouzid; Benedicte Ndeboko; Sandra Durantel; Catherine Jamard; Fabien Zoulim; Thierry Buronfosse; Lucyna Cova
Genetic vaccination for production of DNA-designed antibodies specific to Hepadnavirus envelope proteins.
Vaccine 2006;24(21):4615-7.
2006: Cirley Lobato; José Tavares-Neto; Márcio Rios-Leite; Christian Trepo; Ludmila Vitvitski; Parviz Parvaz; Fabien Zoulim; Argemiro D'Oliveira; Raymundo Paraná
Intrafamilial prevalence of hepatitis B virus in Western Brazilian Amazon region: epidemiologic and biomolecular study.
Journal of gastroenterology and hepatology 2006;21(5):863-8.
2006: Fabien Zoulim
In vitro models for studying hepatitis B virus drug resistance.
Seminars in liver disease 2006;26(2):171-80.
2006: Fabien Zoulim
Entecavir: a new treatment option for chronic hepatitis B.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2006;36(1):8-12.
2006: Olivier Schorr; Christelle Borel; Christian Trepo; Fabien Zoulim; Olivier Hantz
Effects of liver growth factors on hepadnavirus replication in chronically infected duck hepatocytes.
Journal of hepatology 2006;44(5):842-7.
2006: Fabien Zoulim; Thierry Poynard; Françoise Degos; Alain Slama; Abdelkader El Hasnaoui; Patrick Blin; F Mercier; Paul Deny; P Landais; Parviz Parvaz; Christian Trepo
A prospective study of the evolution of lamivudine resistance mutations in patients with chronic hepatitis B treated with lamivudine.
Journal of viral hepatitis 2006;13(4):278-88.
2006: Cynthia Chapel; Céline Garcia; Philippe Roingeard; Nicole Zitzmann; Jean Dubuisson; Raymond A Dwek; Christian Trépo; Fabien Zoulim; David Durantel
Antiviral effect of alpha-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles.
The Journal of general virology 2006;87(Pt 4):861-71.
2006: Anne-Carole Jacquard; Marie-Noëlle Brunelle; Christian Pichoud; David Durantel; Sandra Carrouée-Durantel; Christian Trepo; Fabien Zoulim
In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine.
Antimicrobial agents and chemotherapy 2006;50(3):955-61.
2006: Karine Lacombe; Véronique Massari; Pierre-Marie Girard; Lawrence Serfaty; joel gozlan; Gilles Pialoux; Patrick Mialhes; Jean-Michel Molina; Caroline Lascoux-Combe; Dominique Wendum; Fabrice CARRAT; Fabien Zoulim
Major role of hepatitis B genotypes in liver fibrosis during coinfection with HIV.
AIDS (London, England) 2006;20(3):419-27.
2006: Fabien Zoulim
[New virologic tests and their application in management of chronic hepatitis B].
Presse médicale (Paris, France : 1983) 2006;35(2 Pt 2):317-26.
2006: Fabien Zoulim
Assessment of treatment efficacy in HBV infection and disease.
Journal of hepatology 2006;44(1 Suppl):S95-9.
2005: David Durantel; Marie-Noëlle Brunelle; Edwige Gros; Sandra Carrouée-Durantel; Christian Pichoud; Stéphanie Villet; Christian Trepo; Fabien Zoulim
Resistance of human hepatitis B virus to reverse transcriptase inhibitors: from genotypic to phenotypic testing.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2005;34 Suppl 1():S34-43.
2005: Vanessa Escuret; Vincent Aucagne; Nicolas Joubert; David Durantel; Kimberly L Rapp; Ray F Schinazi; Fabien Zoulim; Luigi A Agrofoglio
Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: antiviral activity and cellular toxicity.
Bioorganic & medicinal chemistry 2005;13(21):6015-24.
2005: Sergio Caldarelli; Mohamed Mehiri; Audrey Di-Giorgio; Amaury Martin; Olivier Hantz; Fabien Zoulim; Raphael Terreux; Roger Condom; Nadia Patino
A cyclic PNA-based compound targeting domain IV of HCV IRES RNA inhibits in vitro IRES-dependent translation.
Bioorganic & medicinal chemistry 2005;13(20):5700-9.
2005: Thierry Poynard; Fabien Zoulim; Vlad Ratziu; Françoise Degos; Françoise Imbert-Bismut; Paul Deny; Paul Landais; Abdelkader El Hasnaoui; Alain Slama; Patrick Blin; Vincent Thibault; Parviz Parvaz; Mona Munteanu; Christian Trepo
Longitudinal assessment of histology surrogate markers (FibroTest-ActiTest) during lamivudine therapy in patients with chronic hepatitis B infection.
The American journal of gastroenterology 2005;100(9):1970-80.
2005: Thierry Bizollon; Pierre Pradat; Jean-Yves Mabrut; Michèle Chevallier; Mustapha Adham; Sylvie Radenne; Jean-Christophe Souquet; Christian Ducerf; Jacques Baulieux; Fabien Zoulim; Christian Trepo
Benefit of sustained virological response to combination therapy on graft survival of liver transplanted patients with recurrent chronic hepatitis C.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(8):1909-13.
2005: Karine Lacombe; joel gozlan; Pierre-Yves Boelle; Lawrence Serfaty; Fabien Zoulim; Alain-jacques Valleron; Pierre-Marie Girard
Long-term hepatitis B virus dynamics in HIV-hepatitis B virus-co-infected patients treated with tenofovir disoproxil fumarate.
AIDS (London, England) 2005;19(9):907-15.
2005: Marie-Noëlle Brunelle; Anne-Carole Jacquard; Christian Pichoud; David Durantel; Sandra Carrouée-Durantel; Jean-Pierre Villeneuve; Christian Trépo; Fabien Zoulim
Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir.
Hepatology (Baltimore, Md.) 2005;41(6):1391-8.
2005: Séverine Margeridon; Alain Lachaux; Christian Trepo; Fabien Zoulim; Alan Campbell Kay
A quasi-monoclonal anti-HBs response can lead to immune escape of 'wild-type' hepatitis B virus.
The Journal of general virology 2005;86(Pt 6):1687-93.
2005: E Khattab; Isabelle Chemin; I Vuillermoz; C Vieux; Saad Mrani; O Guillaud; Christian Trepo; Fabien Zoulim
Analysis of HCV co-infection with occult hepatitis B virus in patients undergoing IFN therapy.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2005;33(2):150-7.
2005: Fabien Zoulim
Combination of nucleoside analogues in the treatment of chronic hepatitis B virus infection: lesson from experimental models.
The Journal of antimicrobial chemotherapy 2005;55(5):608-11.
2005: Vanessa Escuret; Fabien Zoulim
[Treatment of hepatitis C].
La Revue du praticien 2005;55(6):633-45.
2005: Fabien Zoulim
New insight on hepatitis B virus persistence from the study of intrahepatic viral cccDNA.
Journal of hepatology 2005;42(3):302-8.
2005: Thierry Bizollon; Mustapha Adham; Pierre Pradat; Michèle Chevallier; Christian Ducerf; Jacques Baulieux; Fabien Zoulim; Christian Trepo
Triple antiviral therapy with amantadine for IFN-ribavirin nonresponders with recurrent posttransplantation hepatitis C.
Transplantation 2005;79(3):325-9.
2005: Genie Bang; Kyun-Hwan Kim; Michael Guarnieri; Fabien Zoulim; Shigenobu Kawai; Jisu Li; Jack R Wands; Shuping Tong
Effect of mutating the two cysteines required for HBe antigenicity on hepatitis B virus DNA replication and virion secretion.
Virology 2005;332(1):216-24.
2005: Marianne Maynard; Parviz Parvaz; Sandra Durantel; Michèle Chevallier; Philippe Chevallier; Muriel Lot; Christian Trepo; Fabien Zoulim
Sustained HBs seroconversion during lamivudine and adefovir dipivoxil combination therapy for lamivudine failure.
Journal of hepatology 2005;42(2):279-81.
2005: Magdalena Robaczewska; Ramamurthy Narayan; Beatrice Seigneres; Olivier Schorr; Alexandre Thermet; Anna J Podhajska; Christian Trepo; Fabien Zoulim; Peter E Nielsen; Lucyna Cova
Sequence-specific inhibition of duck hepatitis B virus reverse transcription by peptide nucleic acids (PNA).
Journal of hepatology 2005;42(2):180-7.
2004: Pierre Rocca; Liana Codes; Michèle Chevallier; Christian Trépo; Fabien Zoulim
[Autoimmunization induced by interferon alpha therapy in chronic hepatitis C].
Gastroentérologie clinique et biologique 2004;28(11):1173-6.
2004: Fabien Zoulim
Antiviral therapy of chronic hepatitis B: can we clear the virus and prevent drug resistance?
Antiviral chemistry & chemotherapy 2004;15(6):299-305.
2004: Pascal Sève; Philippe Renaudier; Annie J Sasco; Charles Dumontet; Gilles SALLES; Bertrand Coiffier; Fabien Zoulim; Christiane Broussolle; Christian Trépo
Hepatitis C virus infection and B-cell non-Hodgkin's lymphoma: a cross-sectional study in Lyon, France.
European journal of gastroenterology & hepatology 2004;16(12):1361-5.
2004: Stephen Locarnini; Angelos Hatzakis; Jenny Heathcote; Emmet B Keeffe; TSANYANG LIANG; David Mutimer; Jean-Michel Pawlotsky; Fabien Zoulim
Management of antiviral resistance in patients with chronic hepatitis B.
Antiviral therapy 2004;9(5):679-93.
2004: Pierre Rocca; Saïd El Jastimi; Jacques Troncy; Jean-Yves Scoazec; Alexandra Boucher; Thierry Vial; Christian Trépo; Fabien Zoulim
[Imatinib mesylate-induced acute cytolytic hepatitis].
Gastroentérologie clinique et biologique 2004;28(10 Pt 1):918-9.
2004: Fabien Zoulim
Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic hepatitis B virus infection.
Antiviral research 2004;64(1):1-15.
2004: David Durantel; Sandra Carrouée-Durantel; Bettina Werle-Lapostolle; Marie-Noëlle Brunelle; Christian Pichoud; Christian Trépo; Fabien Zoulim
A new strategy for studying in vitro the drug susceptibility of clinical isolates of human hepatitis B virus.
Hepatology (Baltimore, Md.) 2004;40(4):855-64.
2004: I Vuillermoz; E Khattab; E Sablon; I Ottevaere; D Durantel; C Vieux; C Trepo; Fabien Zoulim
Genetic variability of hepatitis C virus in chronically infected patients with viral breakthrough during interferon-ribavirin therapy.
Journal of medical virology 2004;74(1):41-53.
2004: Damien Jeantet; Isabelle Chemin; Bernard Mandrand; Albert Tran; Fabien Zoulim; Philippe Merle; Christian Trepo; Alan Campbell Kay
Cloning and expression of surface antigens from occult chronic hepatitis B virus infections and their recognition by commercial detection assays.
Journal of medical virology 2004;73(4):508-15.
2004: Anne-Carole Jacquard; Michael Nassal; Christian Pichoud; S Ren; Ursula Schultz; Sylviane Guerret; Michèle Chevallier; B Werle; Simone Peyrol; Catherine Jamard; Laurence Rimsky; Christian Trepo; Fabien Zoulim
Effect of a combination of clevudine and emtricitabine with adenovirus-mediated delivery of gamma interferon in the woodchuck model of hepatitis B virus infection.
Antimicrobial agents and chemotherapy 2004;48(7):2683-92.
2004: Bettina Werle-Lapostolle; Scott Bowden; Stephen Locarnini; Karsten Wursthorn; Jörg Petersen; George Lau; Christian Trepo; Patrick Marcellin; Zachary D Goodman; William E Delaney; Shelly Xiong; Carol L Brosgart; Shan-Shan Chen; Craig S Gibbs; Fabien Zoulim
Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy.
Gastroenterology 2004;126(7):1750-8.
2004: Fabien Zoulim; Shuping Tong; Christian Trépo
Study of HBV replication capacity in relation to sequence variation in the precore and core promoter regions.
Methods in molecular medicine 2004;95():235-46.
2004: Lucyna Cova; Fabien Zoulim
Duck hepatitis B virus model in the study of hepatitis B virus.
Methods in molecular medicine 2004;96():261-8.
2004: Olivier Hantz; Fabien Zoulim
Duck hepatitis B virus primary hepatocyte culture model.
Methods in molecular medicine 2004;96():189-97.
2003: Fabien Zoulim
Treatment of pre- and post-liver transplantation HBV infection: Should we aim at combination therapy?
Hepatology (Baltimore, Md.) 2003;38(6):1353-5.
2003: Jean-Pierre Villeneuve; David Durantel; Sandra Durantel; Christopher E Westland; Shelly Xiong; Carol L Brosgart; Craig S Gibbs; Parviz Parvaz; Bettina Werle; Christian Trépo; Fabien Zoulim
Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient.
Journal of hepatology 2003;39(6):1085-9.
2003: David Durantel; Vanessa Escuret; Fabien Zoulim
Current and emerging therapeutic approaches to hepatitis C infection.
Expert review of anti-infective therapy 2003;1(3):441-54.
2003: Erwin Sablon; Fred Shapiro; Fabien Zoulim
Early detection of hepatitis B drug resistance: implications for patient management.
Expert review of molecular diagnostics 2003;3(5):535-47.
2003: Yoshio Saito; Vanessa Escuret; David Durantel; Fabien Zoulim; Ray F Schinazi; Luigi A Agrofoglio
Synthesis of 1,2,3-triazolo-carbanucleoside analogues of ribavirin targeting an HCV in replicon.
Bioorganic & medicinal chemistry 2003;11(17):3633-9.
2003: Sameer Parekh; Fabien Zoulim; Sang Hoon Ahn; Adrienne Tsai; Jisu Li; Shigenobu Kawai; Nasser Khan; Christian Trépo; Jack R Wands; Shuping Tong
Genome replication, virion secretion, and e antigen expression of naturally occurring hepatitis B virus core promoter mutants.
Journal of virology 2003;77(12):6601-12.
2003: Fabien Zoulim
Towards an improved and cost-saving prophylaxis of hepatitis B virus recurrence after liver transplantation?
Journal of hepatology 2003;38(6):850-2.
2003: Béatrice Seignères; Perrine Martin; Bettina Werle; Olivier Schorr; Catherine Jamard; Laurence Rimsky; Christian Trépo; Fabien Zoulim
Effects of pyrimidine and purine analog combinations in the duck hepatitis B virus infection model.
Antimicrobial agents and chemotherapy 2003;47(6):1842-52.
2003: Dominique Salmon-Céron; Régis Lassalle; Alain Pruvost; Henri BENECH; Magali Bouvier-Alias; Christopher Payan; Cécile Goujard; Eric Bonnet; Fabien Zoulim; Philippe Morlat; Philippe Sogni; Sophie Pérusat; Jean-Marc Tréluyer; Geneviève Chêne
Interferon-ribavirin in association with stavudine has no impact on plasma human immunodeficiency virus (HIV) type 1 level in patients coinfected with HIV and hepatitis C virus: a CORIST-ANRS HC1 trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(10):1295-304.
2003: Pierre Rocca; François Bailly; Michèle Chevallier; Philippe Chevallier; Fabien Zoulim; Christian Trépo
[Early treatment of acute hepatitis C with interferon alpha-2b or interferon alpha-2b plus ribavirin: study of sixteen patients].
Gastroentérologie clinique et biologique 2003;27(3 Pt 1):294-9.
2003: Franck Le Guerhier; Alexandre Thermet; Sylviane Guerret; Michèle Chevallier; Catherine Jamard; Craig S Gibbs; Christian Trépo; Lucyna Cova; Fabien Zoulim
Antiviral effect of adefovir in combination with a DNA vaccine in the duck hepatitis B virus infection model.
Journal of hepatology 2003;38(3):328-34.
2003: Fabien Zoulim
[New therapeutic advances in chronic hepatitis B].
Gastroentérologie clinique et biologique 2003;27(2):151-3.
2003: Thierry Bizollon; Si Nafa Si Ahmed; Sylvie Radenne; Michèle Chevallier; Philippe Chevallier; Parviz Parvaz; S Guichard; Christian Ducerf; Jacques Baulieux; Fabien Zoulim; Christian Trepo
Long term histological improvement and clearance of intrahepatic hepatitis C virus RNA following sustained response to interferon-ribavirin combination therapy in liver transplanted patients with hepatitis C virus recurrence.
Gut 2003;52(2):283-7.
2003: Alexandre Thermet; Christine Rollier; Fabien Zoulim; Christian Trepo; Lucyna Cova
Progress in DNA vaccine for prophylaxis and therapy of hepatitis B.
Vaccine 2003;21(7-8):659-62.
2003: Christian Trepo; Marianne Maynard; Fabien Zoulim
Perspectives on therapy of hepatitis B.
Journal of hepatology 2003;39 Suppl 1():S220-3.
2003: Fabien Zoulim
Hepatitis B virus resistance to antivirals: clinical implications and management.
Journal of hepatology 2003;39 Suppl 1():S133-8.
2002: Anna S F Lok; Fabien Zoulim; Stephen Locarnini; alessandra mangia; Grazia Anna Niro; Hilde Decraemer; Geert Maertens; Frank Hulstaert; Karen De Vreese; Erwin Sablon
Monitoring drug resistance in chronic hepatitis B virus (HBV)-infected patients during lamivudine therapy: evaluation of performance of INNO-LiPA HBV DR assay.
Journal of clinical microbiology 2002;40(10):3729-34.
2002: Béatrice Seignères; Christian Pichoud; Perrine Martin; Philip Furman; Christian Trépo; Fabien Zoulim
Inhibitory activity of dioxolane purine analogs on wild-type and lamivudine-resistant mutants of hepadnaviruses.
Hepatology (Baltimore, Md.) 2002;36(3):710-22.
2002: Vanessa Escuret; Parviz Parvaz; Olivier Hantz; Marie-Anne Petit; Christian Trepo; Fabien Zoulim
[Study of the antiviral mechanism of action of ribavirin in the bovine viral diarrhea virus model].
Gastroentérologie clinique et biologique 2002;26(6-7):584-90.
2002: François Bailly; Fabien Zoulim
[Chronic hepatitis B: natural history and treatments].
Gastroentérologie clinique et biologique 2002;26(5):492-500.
2002: Yves Deugnier; Olivier Loréal; François Carré; Andŕe Duvallet; Fabien Zoulim; Jean-Pierre Vinel; Jean Claude Paris; Denis Blaison; Romain Moirand; Bruno Turlin; Yves Gandon; Véronique David; André Mégret; Michel Guinot
Increased body iron stores in elite road cyclists.
Medicine and science in sports and exercise 2002;34(5):876-80.
2002: Damien Jeantet; Isabelle Chemin; Bernard Mandrand; Fabien Zoulim; Christian Trepo; Alan Campbell Kay
Characterization of two hepatitis B virus populations isolated from a hepatitis B surface antigen-negative patient.
Hepatology (Baltimore, Md.) 2002;35(5):1215-24.
2002: Fabien Zoulim
[Treatment of patients with chronic hepatitis C who relapsed or did not respond to a previous treatment].
Gastroentérologie clinique et biologique 2002;26 Spec No 2():B225-30.
2002: Julien Delmas; Olivier Schorr; Catherine Jamard; Craig Gibbs; Christian Trépo; Olivier Hantz; Fabien Zoulim
Inhibitory effect of adefovir on viral DNA synthesis and covalently closed circular DNA formation in duck hepatitis B virus-infected hepatocytes in vivo and in vitro.
Antimicrobial agents and chemotherapy 2002;46(2):425-33.
2002: Fabien Zoulim
Quantification and genotyping in management of chronic hepatitis B and C.
Virus research 2002;82(1-2):45-52.
2002: Fabien Zoulim
Assessing hepatitis B virus resistance in vitro and molecular mechanisms of nucleoside resistance.
Seminars in liver disease 2002;22 Suppl 1():23-31.
2002: Fabien Zoulim
A preliminary benefit-risk assessment of lamivudine for the treatment of chronic hepatitis B virus infection.
Drug safety : an international journal of medical toxicology and drug experience 2002;25(7):497-510.
2002: Fabien Zoulim
[Toward the expected development of therapeutic combinations in hepatitis B?].
Gastroentérologie clinique et biologique 2002;26(1):107-8.
2001: Christelle Borel; Olivier Schorr; I Durand; Fabien Zoulim; Alan Campbell Kay; Christian Trepo; Olivier Hantz
Initial amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of embryonic duck hepatocytes is increased by cell cycle progression.
Hepatology (Baltimore, Md.) 2001;34(1):168-79.
2001: Fabien Zoulim
Detection of hepatitis B virus resistance to antivirals.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2001;21(3):243-53.
2001: Franck Le Guerhier; Christian Pichoud; Catherine Jamard; Sylviane Guerret; Michèle Chevallier; Simone Peyrol; Olivier Hantz; I King; Christian Trépo; YC Cheng; Fabien Zoulim
Antiviral activity of beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine in woodchucks chronically infected with woodchuck hepatitis virus.
Antimicrobial agents and chemotherapy 2001;45(4):1065-77.
2001: Isabelle Chemin; Fabien Zoulim; Philippe Merle; A Arkhis; Michèle Chevallier; Alan Campbell Kay; Lucyna Cova; Philippe Chevallier; Bernard Mandrand; Christian Trépo
High incidence of hepatitis B infections among chronic hepatitis cases of unknown aetiology.
Journal of hepatology 2001;34(3):447-54.
2001: F Querenghi; Q Yu; G Billaud; Geert Maertens; Christian Trépo; Fabien Zoulim
Evolution of hepatitis C virus genome in chronically infected patients receiving ribavirin monotherapy.
Journal of viral hepatitis 2001;8(2):120-31.
2001: Christine Bain; Ahmed Fatmi; Fabien Zoulim; Jean-Pierre Zarski; Christian Trépo; Geneviève Inchauspé
Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection.
Gastroenterology 2001;120(2):512-24.
2001: Fabien Zoulim
Evaluation of novel strategies to combat hepatitis B virus targetting wild-type and drug-resistant mutants in experimental models.
Antiviral chemistry & chemotherapy 2001;12 Suppl 1():131-42.
2001: Béatrice Seignères; S Aguesse-Germon; Christian Pichoud; I Vuillermoz; Catherine Jamard; Christian Trépo; Fabien Zoulim
Duck hepatitis B virus polymerase gene mutants associated with resistance to lamivudine have a decreased replication capacity in vitro and in vivo.
Journal of hepatology 2001;34(1):114-22.
2000: Philippe Merle; Fabien Zoulim; Ludmila Vitvitski; Christian Trépo
[The prophylaxis of hepatocellular carcinoma by interferon-alpha in virus-induced cirrhosis].
Gastroentérologie clinique et biologique 2000;24(12):1166-76.
2000: S Nafa; S Ahmed; D Tavan; Christian Pichoud; F Berby; Lieven Stuyver; M Johnson; P Merle; H Abidi; Christian Trépo; Fabien Zoulim
Early detection of viral resistance by determination of hepatitis B virus polymerase mutations in patients treated by lamivudine for chronic hepatitis B.
Hepatology (Baltimore, Md.) 2000;32(5):1078-88.
2000: C Grandjacques; Pierre Pradat; Lieven Stuyver; Michèle Chevallier; Philippe Chevallier; Christian Pichoud; Mireille Maisonnas; Christian Trépo; Fabien Zoulim
Rapid detection of genotypes and mutations in the pre-core promoter and the pre-core region of hepatitis B virus genome: correlation with viral persistence and disease severity.
Journal of hepatology 2000;33(3):430-9.
2000: Béatrice Seignères; Christian Pichoud; S S Ahmed; Olivier Hantz; Christian Trépo; Fabien Zoulim
Evolution of hepatitis B virus polymerase gene sequence during famciclovir therapy for chronic hepatitis B.
The Journal of infectious diseases 2000;181(4):1221-33.
2000: Olivier Hantz; Jean-Louis Kraus; Fabien Zoulim
Design and evaluation of hepatitis B virus inhibitors.
Current pharmaceutical design 2000;6(5):503-23.
2000: Christian Pichoud; F Berby; Lieven Stuyver; M A Petit; Christian Trépo; Fabien Zoulim
Persistence of viral replication after anti-HBe seroconversion during antiviral therapy for chronic hepatitis B.
Journal of hepatology 2000;32(2):307-16.
2000: Franck Le Guerhier; Christian Pichoud; Sylviane Guerret; Michèle Chevallier; Catherine Jamard; Olivier Hantz; X Y Li; S H Chen; I King; Christian Trépo; YC Cheng; Fabien Zoulim
Characterization of the antiviral effect of 2',3'-dideoxy-2', 3'-didehydro-beta-L-5-fluorocytidine in the duck hepatitis B virus infection model.
Antimicrobial agents and chemotherapy 2000;44(1):111-22.
1999: Fabien Zoulim
Therapy of chronic hepatitis B virus infection: inhibition of the viral polymerase and other antiviral strategies.
Antiviral research 1999;44(1):1-30.
1999: C Broussolle; M P Steineur; F Bailly; Fabien Zoulim; Christian Trépo
[Hepatitis C virus infection and thyroid diseases].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 1999;20(9):766-73.
1999: F Romand; M Michallet; C Pichoud; C Trépo; Fabien Zoulim
[Hepatitis B virus reactivation after allogeneic bone marrow transplantation in a patient previously cured of hepatitis B].
Gastroentérologie clinique et biologique 1999;23(6-7):770-4.
1999: Olivier Hantz; C Périgaud; Christelle Borel; Catherine Jamard; Fabien Zoulim; Christian Trépo; J L Imbach; G Gosselin
The SATE pronucleotide approach applied to acyclovir: part II. Effects of bis(SATE)phosphotriester derivatives of acyclovir on duck hepatitis B virus replication in vitro and in vivo.
Antiviral research 1999;40(3):179-87.
1999: Christian Pichoud; Béatrice Seignères; Z Wang; Christian Trépo; Fabien Zoulim
Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance.
Hepatology (Baltimore, Md.) 1999;29(1):230-7.
1998: F Habersetzer; Fabien Zoulim; J F Jusot; X Zhang; Mary-Anne Trabaud; Philippe Chevallier; Michèle Chevallier; Si Nafa Si Ahmed; Maurice Sepetjan; Lorraine Comanor; James Minor; Christian Trépo
Clinical evaluation of the branched DNA assay for hepatitis B virus DNA detection in patients with chronic hepatitis B lacking hepatitis B e antigen and treated with interferon-alpha.
Journal of viral hepatitis 1998;5(6):407-14.
1998: Fabien Zoulim; J Haem; S S Ahmed; P Chossegros; F Habersetzer; Michèle Chevallier; François Bailly; Christian Trépo
Ribavirin monotherapy in patients with chronic hepatitis C: a retrospective study of 95 patients.
Journal of viral hepatitis 1998;5(3):193-8.
1998: S Aguesse-Germon; S H Liu; Michèle Chevallier; Christian Pichoud; Catherine Jamard; Christelle Borel; Chung (David) K. Chu; Christian Trépo; YC Cheng; Fabien Zoulim
Inhibitory effect of 2'-fluoro-5-methyl-beta-L-arabinofuranosyl-uracil on duck hepatitis B virus replication.
Antimicrobial agents and chemotherapy 1998;42(2):369-76.
1998: C Trabaud; J Dessolin; Michel Camplo; Olivier Hantz; Fabien Zoulim; Christelle Borel; M Meyer; G Pepe; Jean-Claude Chermann; Jean-Louis Kraus
Design, synthesis and structure relationships of new N,N',N",N"'-tetrakis (omega-amino alkyl) tetraazamacrocycles.
Antiviral chemistry & chemotherapy 1998;9(1):73-84.
1997: Olivier Hantz; Christelle Borel; C Trabaud; Fabien Zoulim; J Dessolin; Michel Camplo; Patrick Vlieghe; M Bouygues; Christian Trepo; Jean-Louis Kraus
Selective inhibition of the duck hepatitis B virus by a new class of tetraazamacrocycles.
Antimicrobial agents and chemotherapy 1997;41(11):2579-81.
1997: Jérôme Dumortier; S Durupt; Michèle Chevallier; Christian Trépo; Fabien Zoulim
[Favorable course of hepatitis B virus reactivation with hepatocellular insufficiency by a treatment combining corticoids, foscarnet and ganciclovir].
Gastroentérologie clinique et biologique 1997;21(12):982-6.
1996: Fabien Zoulim; X Zhang; Christian Pichoud; C Trepo
Heterogeneity of hepatitis B virus (HBV) core gene in a patient with HBV-associated cirrhosis and serum negativity for anti-HBc.
Journal of hepatology 1996;24(2):155-60.
1996: Fabien Zoulim; E Dannaoui; Christelle Borel; Olivier Hantz; T S Lin; S H Liu; Christian Trépo; Y C Cheng
2',3'-dideoxy-beta-L-5-fluorocytidine inhibits duck hepatitis B virus reverse transcription and suppresses viral DNA synthesis in hepatocytes, both in vitro and in vivo.
Antimicrobial agents and chemotherapy 1996;40(2):448-53.
1996: X Zhang; Fabien Zoulim; F Habersetzer; S Xiong; Christian Trépo
Analysis of hepatitis B virus genotypes and pre-core region variability during interferon treatment of HBe antigen negative chronic hepatitis B.
Journal of medical virology 1996;48(1):8-16.
1995: Fabien Zoulim; F Capel; P Berthillon; Christian Trépo; M A Petit
[Clinical and virological evaluation of the detection of pre-S1 and pre-S2 antigens in serum from patients with chronic hepatitis B].
Gastroentérologie clinique et biologique 1995;19(12):970-5.
1995: J P Lamelin; Fabien Zoulim; C Trépo
Lymphotropism of hepatitis B and C viruses: an update and a newcomer.
International journal of clinical & laboratory research 1995;25(1):1-6.
1994: I Chemin; C Vermot-Desroches; I Baginski; J C Saurin; F Laurent; Fabien Zoulim; Janine Bernaud; J P Lamelin; Olivier Hantz; Dominique Rigal
Selective detection of human hepatitis B virus surface and core antigens in peripheral blood mononuclear cell subsets by flow cytometry.
Journal of viral hepatitis 1994;1(1):39-44.
1994: M A Petit; Fabien Zoulim; P Berthillon; F Capel; J Li; C Dauguet; C Ferrari; Christian Trépo
PreS1 antigen/antibody patterns following interferon therapy in acute and chronic hepatitis B.
Journal of hepatology 1994;20(1):47-56.
1993: X Causse; H Godinot; Michèle Chevallier; P Chossegros; Fabien Zoulim; J P Zarski; C Meschiewitz; J Albrecht; Christian Trépo
Simultaneous steroids/interferon therapy in chronic hepatitis B.
Journal of hepatology 1993;17(1):128-9.
1993: C Trépo; Fabien Zoulim; C Alonso; M A Petit; Christian Pichoud; L Vitvitski
Diagnostic markers of viral hepatitis B and C.
Gut 1993;34(2 Suppl):S20-5.
1992: P Bouffard; J P Lamelin; Fabien Zoulim; D Lepot; Christian Trepo
Phytohemagglutinin and concanavalin A activate hepatitis B virus in peripheral blood mononuclear cells of patients with chronic hepatitis B virus infection.
Journal of medical virology 1992;37(4):255-62.
1992: Fabien Zoulim; L Mimms; M Floreani; Christian Pichoud; I Chemin; Alan Campbell Kay; L Vitvitski; Christian Trepo
New assays for quantitative determination of viral markers in management of chronic hepatitis B virus infection.
Journal of clinical microbiology 1992;30(5):1111-9.
1992: Jean-Louis Gaudin; X Causse; Fabien Zoulim; Michèle Chevallier; Christian Trépo
[Recovery of chronic hepatitis B- delta infection by zidovudine and recombinant interferon alpha combination therapy in a patient with Kaposi's sarcoma associated with HIV infection].
Gastroentérologie clinique et biologique 1992;16(5):468-72.
1992: I Chemin; C Vermot-Desroches; I Baginski; J C Saurin; F Laurent; Fabien Zoulim; Janine Bernaud; J P Lamelin; Olivier Hantz; Dominique Rigal
Selective detection of human hepatitis B virus surface and core antigens in some peripheral blood mononuclear cell subsets by flow cytometry.
Journal of clinical & laboratory immunology 1992;38(2):63-71.
1992: Fabien Zoulim; J Li; I Baginski; J P Lamelin; Christian Trépo
[Enzymatic amplification of sequences of viral nucleic acids. A methodological revolution promising new prospects in hepatology].
Gastroentérologie clinique et biologique 1992;16(5):443-53.
1992: M A Petit; F Capel; Fabien Zoulim; S Dubanchet; I Chemin; A Penna; C Ferrari; Christian Trépo
PreS antigen expression and anti-preS response in hepatitis B virus infections: relationship to serum HBV-DNA, intrahepatic HBcAg, liver damage and specific T-cell response.
Archives of virology. Supplementum 1992;4():105-12.
1991: X Causse; H Godinot; Michèle Chevallier; P Chossegros; Fabien Zoulim; D Ouzan; J P Heyraud; T Fontanges; J Albrecht; C Meschievitz
Comparison of 1 or 3 MU of interferon alfa-2b and placebo in patients with chronic non-A, non-B hepatitis.
Gastroenterology 1991;101(2):497-502.
1991: Fabien Zoulim; L Vitvitski; P Bouffard; Christian Pichoud; P Rougier; J P Lamelin; Christian Trépo
Detection of pre-S1 proteins in peripheral blood mononuclear cells from patients with HBV infection.
Journal of hepatology 1991;12(2):150-6.
1991: I Chemin; I Baginski; M A Petit; Fabien Zoulim; Christian Pichoud; F Capel; Olivier Hantz; Christian Trepo
Correlation between HBV DNA detection by polymerase chain reaction and Pre-S1 antigenemia in symptomatic and asymptomatic hepatitis B virus infections.
Journal of medical virology 1991;33(1):51-7.
1990: J Li; S Tong; L Vitvitski; Fabien Zoulim; Christian Trépo
Rapid detection and further characterization of infection with hepatitis B virus variants containing a stop codon in the distal pre-C region.
The Journal of general virology 1990;71 ( Pt 9)():1993-8.
1990: P Bouffard; J P Lamelin; Fabien Zoulim; Christian Pichoud; Christian Trepo
Different forms of hepatitis B virus DNA and expression of HBV antigens in peripheral blood mononuclear cells in chronic hepatitis B.
Journal of medical virology 1990;31(4):312-7.
1990: F Jenhani; Khaled Ayed; Yousr Gorgi; Fabien Zoulim; Christian Pichoud; C Trepo
Delta infection in chronic HBs Ag carriers in Tunisia: high prevalence in chronic asymptomatic HBs Ag carriers and in HBs Ag positive cirrhosis.
Annals of tropical medicine and parasitology 1990;84(4):349-53.
1990: M A Petit; Fabien Zoulim; F Capel; S Dubanchet; C Dauguet; C Trepo
Variable expression of preS1 antigen in serum during chronic hepatitis B virus infection: an accurate marker for the level of hepatitis B virus replication.
Hepatology (Baltimore, Md.) 1990;11(5):809-14.
1990: Fabien Zoulim; J P Lamelin; Christian Trepo
[Clinical implications of interactions between hepatitis B virus and mononuclear leukocytes].
Gastroentérologie clinique et biologique 1990;14(3):255-62.
1990: Christian Trépo; I Chemin; M A Petit; P Chossegros; Fabien Zoulim; P Chevallier; Maurice Sepetjan
Possible prevention of chronic hepatitis B by early interferon therapy.
Journal of hepatology 1990;11 Suppl 1():S95-9.
1989: Fabien Zoulim; L Vitvitski; Christian Pichoud; J P Lamelin; Christian Trépo
[Significance of the expression of pre-S proteins in mononuclear blood cells in chronic hepatitis caused by the hepatitis B virus].
Gastroentérologie clinique et biologique 1989;13(8-9):707-11.