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Michael Brown

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Barry M Diner; Christopher R Carpenter; Tara O'Connell; Peter Pang; Michael D Brown; Rawle A Seupaul; James J Celentano; Dan Mayer
Graduate medical education and knowledge translation: role models, information pipelines, and practice change thresholds.
Lyra M Booker; Geoffrey M Habermacher; Benjamin C Jessie; Qi Carrie Sun; Amanda K Baumann; Mahul B Amin; So Dug Lim; Carina Fernandez-Golarz; Robert H Lyles; Michael D Brown; Fray F Marshall; John Petros
North American white mitochondrial haplogroups in prostate and renal cancer.
Elena B Starikovskaya; Rem I Sukernik; Olga A Derbeneva; Natalia V Volodko; Eduardo Ruiz-Pesini; Antonio Torroni; Michael D Brown; Marie T Lott; Seyed H Hosseini; Kirsi Huoponen; Douglas C Wallace
Mitochondrial DNA diversity in indigenous populations of the southern extent of Siberia, and the origins of Native American haplogroups.

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All Publications

2007: Barry M Diner; Christopher R Carpenter; Tara O'Connell; Peter Pang; Michael D Brown; Rawle A Seupaul; James J Celentano; Dan Mayer
Graduate medical education and knowledge translation: role models, information pipelines, and practice change thresholds.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2007;14(11):1008-14.
2006: Lyra M Booker; Geoffrey M Habermacher; Benjamin C Jessie; Qi Carrie Sun; Amanda K Baumann; Mahul B Amin; So Dug Lim; Carina Fernandez-Golarz; Robert H Lyles; Michael D Brown; Fray F Marshall; John Petros
North American white mitochondrial haplogroups in prostate and renal cancer.
The Journal of urology 2006;175(2):468-72; discussion 472-3.
2005: Elena B Starikovskaya; Rem I Sukernik; Olga A Derbeneva; Natalia V Volodko; Eduardo Ruiz-Pesini; Antonio Torroni; Michael D Brown; Marie T Lott; Seyed H Hosseini; Kirsi Huoponen; Douglas C Wallace
Mitochondrial DNA diversity in indigenous populations of the southern extent of Siberia, and the origins of Native American haplogroups.
Annals of human genetics 2005;69(Pt 1):67-89.
2003: Dan Mishmar; Eduardo Ruiz-Pesini; Pawel Golik; Vincent Macaulay; andrew clark; Seyed Hosseini; Martin Brandon; Kirk Easley; Estella Chen; Michael D Brown; Rem I Sukernik; Antonel Olckers; Douglas C Wallace
Natural selection shaped regional mtDNA variation in humans.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(1):171-6.
2002: Michael D Brown; Elena Starikovskaya; Olga A Derbeneva; Seyed Hosseini; Jon C Allen; Irina E Mikhailovskaya; Rem I Sukernik; Douglas C Wallace
The role of mtDNA background in disease expression: a new primary LHON mutation associated with Western Eurasian haplogroup J.
Human genetics 2002;110(2):130-8.
2001: Michael D Brown; Jon C Allen; Gregory P Van Stavern; Nancy J Newman; Douglas C Wallace
Clinical, genetic, and biochemical characterization of a Leber hereditary optic neuropathy family containing both the 11778 and 14484 primary mutations.
American journal of medical genetics 2001;104(4):331-8.
2001: Michael D Brown; S Zhadanov; Jon C Allen; Seyed Hosseini; Nancy J Newman; V V Atamonov; I E Mikhailovskaya; Rem I Sukernik; Douglas C Wallace
Novel mtDNA mutations and oxidative phosphorylation dysfunction in Russian LHON families.
Human genetics 2001;109(1):33-9.
2000: Michael D Brown; IA Trounce; Albert S Jun; Jon C Allen; Douglas C Wallace
Functional analysis of lymphoblast and cybrid mitochondria containing the 3460, 11778, or 14484 Leber's hereditary optic neuropathy mitochondrial DNA mutation.
The Journal of biological chemistry 2000;275(51):39831-6.
2000: IA Trounce; J Schmiedel; H C Yen; Seyed Hosseini; Michael D Brown; Jeffrey J Olson; Douglas C Wallace
Cloning of neuronal mtDNA variants in cultured cells by synaptosome fusion with mtDNA-less cells.
Nucleic acids research 2000;28(10):2164-70.
1999: Douglas C Wallace; Michael D Brown; Marie T Lott
Mitochondrial DNA variation in human evolution and disease.
Gene 1999;238(1):211-30.
1998: Michael D Brown; Seyed H Hosseini; Antonio Torroni; Hans-Jürgen Bandelt; J C Allen; Theodore G Schurr; Rosaria Scozzari; Fulvio Cruciani; Douglas C Wallace
mtDNA haplogroup X: An ancient link between Europe/Western Asia and North America?
American journal of human genetics 1998;63(6):1852-61.
1998: Douglas C Wallace; Michael D Brown; Simon Melov; B Graham; Marie T Lott
Mitochondrial biology, degenerative diseases and aging.
BioFactors (Oxford, England) 1998;7(3):187-90.
1998: AM Kogelnik; Marie T Lott; Michael D Brown; Shamkant B Navathe; Douglas C Wallace
MITOMAP: a human mitochondrial genome database--1998 update.
Nucleic acids research 1998;26(1):112-5.
1997: Douglas C Wallace; C Stugard; DG Murdock; Theodore G Schurr; Michael D Brown
Ancient mtDNA sequences in the human nuclear genome: a potential source of errors in identifying pathogenic mutations.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14900-5.
1997: J T Lell; Michael D Brown; Theodore G Schurr; Rem I Sukernik; Yelena B Starikovskaya; Antonio Torroni; L G Moore; G M Troup; Douglas C Wallace
Y chromosome polymorphisms in native American and Siberian populations: identification of native American Y chromosome haplotypes.
Human genetics 1997;100(5-6):536-43.
1997: Valérie Biousse; Michael D Brown; Nancy J Newman; Jon C Allen; J Rosenfeld; G Meola; Douglas C Wallace
De novo 14484 mitochondrial DNA mutation in monozygotic twins discordant for Leber's hereditary optic neuropathy.
Neurology 1997;49(4):1136-8.
1997: Michael D Brown; F Sun; Douglas C Wallace
Clustering of Caucasian Leber hereditary optic neuropathy patients containing the 11778 or 14484 mutations on an mtDNA lineage.
American journal of human genetics 1997;60(2):381-7.
1997: AM Kogelnik; Marie T Lott; Michael D Brown; Shamkant B Navathe; Douglas C Wallace
MITOMAP: an update on the status of the human mitochondrial genome database.
Nucleic acids research 1997;25(1):196-9.
1996: Albert S Jun; I A Trounce; Michael D Brown; J M Shoffner; Douglas C Wallace
Use of transmitochondrial cybrids to assign a complex I defect to the mitochondrial DNA-encoded NADH dehydrogenase subunit 6 gene mutation at nucleotide pair 14459 that causes Leber hereditary optic neuropathy and dystonia.
Molecular and cellular biology 1996;16(3):771-7.
1996: Michael D Brown; J M Shoffner; Y L Kim; Albert S Jun; B H Graham; M F Cabell; D S Gurley; Douglas C Wallace
Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients.
American journal of medical genetics 1996;61(3):283-9.
1996: AM Kogelnik; Marie T Lott; Michael D Brown; Shamkant B Navathe; Douglas C Wallace
MITOMAP: a human mitochondrial genome database.
Nucleic acids research 1996;24(1):177-9.
1995: J M Shoffner; Michael D Brown; C Stugard; Albert S Jun; S Pollock; Richard Haas; A Kaufman; D Koontz; Y Kim; J R Graham
Leber's hereditary optic neuropathy plus dystonia is caused by a mitochondrial DNA point mutation.
Annals of neurology 1995;38(2):163-9.
1995: Douglas C Wallace; J M Shoffner; I Trounce; Michael D Brown; S W Ballinger; M Corral-Debrinski; T Horton; Albert S Jun; M T Lott
Mitochondrial DNA mutations in human degenerative diseases and aging.
Biochimica et biophysica acta 1995;1271(1):141-51.
1995: Y L Kim; Michael D Brown; Douglas C Wallace
Single-strand conformation polymorphism analysis for the detection of point mutations in the mitochondrial DNA.
Analytical biochemistry 1995;224(2):608-11.
1995: Michael D Brown; Antonio Torroni; C L Reckord; Douglas C Wallace
Phylogenetic analysis of Leber's hereditary optic neuropathy mitochondrial DNA's indicates multiple independent occurrences of the common mutations.
Human mutation 1995;6(4):311-25.
1995: Antonio Torroni; Michael D Brown; M T Lott; Nancy J Newman; Douglas C Wallace
African, Native American, and European mitochondrial DNAs in Cubans from Pinar del Rio Province and implications for the recent epidemic neuropathy in Cuba. Cuba Neuropathy Field Investigation Team.
Human mutation 1995;5(4):310-7.
1994: Nancy J Newman; Antonio Torroni; Michael D Brown; M T Lott; M M Fernandez; Douglas C Wallace
Epidemic neuropathy in Cuba not associated with mitochondrial DNA mutations found in Leber's hereditary optic neuropathy patients. Cuba Neuropathy Field Investigation Team.
American journal of ophthalmology 1994;118(2):158-68.
1994: Albert S Jun; Michael D Brown; Douglas C Wallace
A mitochondrial DNA mutation at nucleotide pair 14459 of the NADH dehydrogenase subunit 6 gene associated with maternally inherited Leber hereditary optic neuropathy and dystonia.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):6206-10.
1994: Michael D Brown; Douglas C Wallace
Molecular basis of mitochondrial DNA disease.
Journal of bioenergetics and biomembranes 1994;26(3):273-89.
1993: Antonio Torroni; Theodore G Schurr; M F Cabell; Michael D Brown; J V Neel; M Larsen; D G Smith; C M Vullo; Douglas C Wallace
Asian affinities and continental radiation of the four founding Native American mtDNAs.
American journal of human genetics 1993;53(3):563-90.
1993: J M Shoffner; Michael D Brown; Antonio Torroni; M T Lott; M F Cabell; Suzanne S Mirra; M Flint Beal; C C Yang; Marla Gearing; R Salvo
Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.
Genomics 1993;17(1):171-84.
1992: Michael D Brown; C C Yang; I Trounce; Antonio Torroni; M T Lott; Douglas C Wallace
A mitochondrial DNA variant, identified in Leber hereditary optic neuropathy patients, which extends the amino acid sequence of cytochrome c oxidase subunit I.
American journal of human genetics 1992;51(2):378-85.
1992: Michael D Brown; A S Voljavec; M T Lott; I MacDonald; Douglas C Wallace
Leber's hereditary optic neuropathy: a model for mitochondrial neurodegenerative diseases.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(10):2791-9.
1992: Michael D Brown; A S Voljavec; M T Lott; Antonio Torroni; C C Yang; Douglas C Wallace
Mitochondrial DNA complex I and III mutations associated with Leber's hereditary optic neuropathy.
Genetics 1992;130(1):163-73.
1992: Douglas C Wallace; M T Lott; J M Shoffner; Michael D Brown
Diseases resulting from mitochondrial DNA point mutations.
Journal of inherited metabolic disease 1992;15(4):472-9.