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Alimuddin Zumla

Research Profile

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Mycobacterium tuberculosis

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TOP 3
Alimuddin Zumla; Payam Nahid; Stewart T Cole
Advances in the development of new tuberculosis drugs and treatment regimens.
William A Wells; Matteo Zignol; Alimuddin Zumla; Catharina C Boehme; Frank Gj Cobelens; Colleen Daniels; David Wesley Dowdy; Elizabeth Gardiner; Jan Gheuens; Peter Kim; Michael E Kimerling; Barry Kreiswirth; Christian Lienhardt; Khisi Mdluli; Madhukar Pai; Mark D Perkins; Trevor Peter; Marco Schito
Alignment of new tuberculosis drug regimens and drug susceptibility testing: a framework for action.
Ben J Marais; Ziad A Memish; Giovanni Battista Migliori; Peter Mwaba; Guiseppe Pantaleo; Michel Pletschette; Marco Schito; Soumya Swaminathan; Afia Zafar; Lynn Zijenah; Ibrahim Abubakar; Matthew Bates; Ruth Colagiuri; Gill Craig; Philippe Glaziou; Rumina Hasan; Michael Hoelscher; Peter Kim; Stephen D Lawn; Knut Lönnroth; Markus Maeurer; Alimuddin Zumla
Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts.

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All Publications

2013: Alimuddin Zumla; Payam Nahid; Stewart T Cole
Advances in the development of new tuberculosis drugs and treatment regimens.
Nature reviews. Drug discovery 2013;12(5):388-404.
2013: William A Wells; Matteo Zignol; Alimuddin Zumla; Catharina C Boehme; Frank Gj Cobelens; Colleen Daniels; David Wesley Dowdy; Elizabeth Gardiner; Jan Gheuens; Peter Kim; Michael E Kimerling; Barry Kreiswirth; Christian Lienhardt; Khisi Mdluli; Madhukar Pai; Mark D Perkins; Trevor Peter; Marco Schito
Alignment of new tuberculosis drug regimens and drug susceptibility testing: a framework for action.
The Lancet infectious diseases 2013;13(5):449-58.
2013: Ben J Marais; Ziad A Memish; Giovanni Battista Migliori; Peter Mwaba; Guiseppe Pantaleo; Michel Pletschette; Marco Schito; Soumya Swaminathan; Afia Zafar; Lynn Zijenah; Ibrahim Abubakar; Matthew Bates; Ruth Colagiuri; Gill Craig; Philippe Glaziou; Rumina Hasan; Michael Hoelscher; Peter Kim; Stephen D Lawn; Knut Lönnroth; Markus Maeurer; Alimuddin Zumla
Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts.
The Lancet infectious diseases 2013;13(5):436-48.
2013: Brian McCloskey; Gwen Stephens; Alimuddin Zumla; David L Heymann; Ziad A Memish
Applying lessons from SARS to a newly identified coronavirus.
The Lancet infectious diseases 2013;13(5):384-5.
2013: Sahal Al-Hajoj; Mais Al-Herbwai; Ruba Al-Omari; Fahad A Alrabiah; Abdulrahman A Alrajhi; Sahar I Al-Thawadi; Mario C Raviglione; Mohammed M Shoukri; Bright Varghese; Matteo Zignol; Alimuddin Zumla; Naila Abuljadayel; Ziad Memish
Epidemiology of antituberculosis drug resistance in saudi arabia: findings of the first national survey.
Antimicrobial agents and chemotherapy 2013;57(5):2161-6.
2013: Matthew Bates; Victor Mudenda; Peter Mwaba; Alimuddin Zumla
Deaths due to respiratory tract infections in Africa: a review of autopsy studies.
Current opinion in pulmonary medicine 2013;19(3):229-37.
2013: Jaffar A Al-Tawfiq; Alimuddin Zumla; Ziad A Memish
Respiratory tract infections during the annual Hajj: potential risks and mitigation strategies.
Current opinion in pulmonary medicine 2013;19(3):192-7.
2013: Alimuddin Zumla
Current trends and newer concepts on diagnosis, management and prevention of respiratory tract infections.
Current opinion in pulmonary medicine 2013;19(3):189-91.
2013: Kate Reddington; Nina Tuite; Thomas Barry; Justin O'Grady; Alimuddin Zumla
Advances in multiparametric molecular diagnostics technologies for respiratory tract infections.
Current opinion in pulmonary medicine 2013;19(3):298-304.
2013: Petter Brodin; Jonas Mattsson; Michael Uhlin; Davide Valentini; Alimuddin Zumla; Markus J Maeurer
Systems level immune response analysis and personalized medicine.
Expert review of clinical immunology 2013;9(4):307-17.
2013: Robert S Wallis; Bruno B Andrade; Stewart Cole; Debra Hanna; Peter Kim; Markus Maeurer; Marco Schito; Alimuddin Zumla
Tuberculosis biomarkers discovery: developments, needs, and challenges.
The Lancet infectious diseases 2013;13(4):362-72.
2013: Stephen D Lawn; Markus Maeurer; Ben J Marais; Timothy D McHugh; Ruth McNerney; Ziad A Memish; Giovanni Battista Migliori; Peter Mwaba; Amy Piatek; Marco Schito; Lynn Zijenah; Ibrahim Abubakar; Heather Alexander; Matthew Bates; Luis E Cuevas; Michael Hoelscher; Nathan Kapata; Peter Kim; Alimuddin Zumla
Advances in tuberculosis diagnostics: the Xpert MTB/RIF assay and future prospects for a point-of-care test.
The Lancet infectious diseases 2013;13(4):349-61.
2013: Ben J Marais; Stephen M Graham; Markus Maeurer; Alimuddin Zumla
Progress and challenges in childhood tuberculosis.
The Lancet infectious diseases 2013;13(4):287-9.
2013: Alimuddin Zumla; Peter Kim; Markus Maeurer; Marco Schito
Zero deaths from tuberculosis: progress, reality, and hope.
The Lancet infectious diseases 2013;13(4):285-7.
2013: Nathan Kapata; Ben Marais; Peter Mwaba; Justin O'Grady; Matthew Bates; Pascalina Chanda-Kapata; Frank Cobelens; Martin Grobusch; Saskia Janssen; Alimuddin Zumla
Trends in childhood tuberculosis in Zambia: a situation analysis.
Journal of tropical pediatrics 2013;59(2):134-9.
2013: Alimuddin Zumla; Richard Hafner; Mario Raviglione; C Fordham von Reyn
Tuberculosis.
The New England journal of medicine 2013;368(8):745-55.
2013: Ben J Marais; Alimuddin Zumla
History of tuberculosis and drug resistance.
The New England journal of medicine 2013;368(1):88.
2013: Niaina Rakotosamimanana; Lova H Andriamihantasoa; Timothy Doherty; Brigitte Gicquel; Vincent Richard; Jean-Louis Soares; Alimuddin Zumla; Voahangy Rasolofo Razanamparany
Expression of TNF-Alpha-Dependent Apoptosis-Related Genes in the Peripheral Blood of Malagasy Subjects with Tuberculosis.
PloS one 2013;8(4):e61154.
2013: Rebecca Axelsson-Robertson; Marthie M Ehlers; Marleen M Kock; André G Loxton; Gerhard Walzl; Alimuddin Zumla; Markus J Maeurer
A Broad Profile of Co-Dominant Epitopes Shapes the Peripheral Mycobacterium tuberculosis Specific CD8+ T-Cell Immune Response in South African Patients with Active Tuberculosis.
PloS one 2013;8(3):e58309.
2013: Nancy Alvarez-Corrales; Kithiganahalli N Balaji; Sven E Hoffner; L Pineda-Garcia; Rebeca Rivera; Carol A Rodriguez; Ramakrishna Sompallae; Nalini K Vudattu; Alimuddin Zumla; Raija K Ahmed; Markus Maeurer
Differential cellular recognition pattern to M. tuberculosis targets defined by IFN-γ and IL-17 production in blood from TB + patients from Honduras as compared to health care workers: TB and immune responses in patients from Honduras.
BMC infectious diseases 2013;13():125.
2013: Matthew Bates; Chishala Chabala; Lophina Chilukutu; Mumba Chomba; Petra Clowes; Michael Hoelscher; Nathan Kapata; Richard Kasonde; Markus Maeurer; Lukundo Mukonda; Peter Mulota; Maxwell Mumba; Peter Mwaba; Judith Mzyece; Justin O'Grady; Andrea Rachow; John Tembo; Alimuddin Zumla
Assessment of the Xpert MTB/RIF assay for diagnosis of tuberculosis with gastric lavage aspirates in children in sub-Saharan Africa: a prospective descriptive study.
The Lancet infectious diseases 2013;13(1):36-42.
2012: Giovanni Sotgiu; Antonio Spanevello; Zarir F Udwadia; Miquel Villar; Elisabetta Zampogna; Jean-Pierre Zellweger; Alimuddin Zumla; Giesela F Schecter; Tae S Shim; Rupak Singla; Alena Skrahina; Jan-William C Alffenaar; Holly A Anger; Jose A Caminero; Paolo Castiglia; Rosella Centis; Lia D'Ambrosio; Saverio De Lorenzo; Giovanni Ferrara; Won-Jung Koh; Giovanni Battista Migliori
Efficacy, safety and tolerability of linezolid containing regimens in treating MDR-TB and XDR-TB: systematic review and meta-analysis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2012;40(6):1430-42.
2012: Justin O'Grady; Andrea Rachow; John Tembo; Matthew Bates; Busiku Cheelo; Moses Chilufya; Lophina Chilukutu; Mumba Chomba; Petra Clowes; Michael Hoelscher; Nathan Kapata; Markus Maeurer; Lukundo Mukonda; Maxwell Mumba; Peter Mwaba; Judith Mzyece; Alimuddin Zumla
Evaluation of the Xpert MTB/RIF assay at a tertiary care referral hospital in a setting where tuberculosis and HIV infection are highly endemic.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012;55(9):1171-8.
2012: Giovanni Ferrara; Alimuddin Zumla; Markus Maeurer
Intravenous immunoglobulin (IVIg) for refractory and difficult-to-treat infections.
The American journal of medicine 2012;125(10):1036.e1-8.
2012: Alimuddin Zumla; Ronald H Behrens; Ziad A Memish
Travel medicine.
Infectious disease clinics of North America 2012;26(3):xiii-xvi.
2012: Andrew Ustianowski; Alimuddin Zumla
Eosinophilia in the returning traveler.
Infectious disease clinics of North America 2012;26(3):781-9.
2012: Matthew Bates; Victor Mudenda; Justin O'Grady; Aaron Shibemba; Alimuddin Zumla
New global estimates of malaria deaths.
Lancet 2012;380(9841):560-1.
2012: Abdullah Al Rabeeah; Maurizio Barbeschi; David Heymann; Brian McCloskey; Ziad A Memish; Ahmad Moolla; Shuja Shafi; Alimuddin Zumla; Richard Horton
Mass gatherings medicine and global health security.
Lancet 2012;380(9836):3-4.
2012: Kate Reddington; Dick Van Soolingen; Alimuddin Zumla; Thomas Barry; Matthew Bates; Stefan Niemann; Justin O'Grady
SeekTB, a two-stage multiplex real-time-PCR-based method for differentiation of the Mycobacterium tuberculosis complex.
Journal of clinical microbiology 2012;50(7):2203-6.
2012: Alimuddin Zumla; Jennifer Keiser
Preface: tropical diseases.
Infectious disease clinics of North America 2012;26(2):xv-xvii.
2012: Alimuddin Zumla; Andrew Ustianowski
Tropical diseases: definition, geographic distribution, transmission, and classification.
Infectious disease clinics of North America 2012;26(2):195-205.
2012: Mario C Raviglione; Karin Weyer; JM Chakaya; Stewart Cole; Katherine Floyd; Haileyesus Getahun; Steve Graham; Anthony D Harries; Stefan H E Kaufmann; Christian Lienhardt; Knut Lönnroth; Ben Marais; Giovanni B Migliori; Paul Nunn; Alimuddin Zumla
Scaling up interventions to achieve global tuberculosis control: progress and new developments.
Lancet 2012;379(9829):1902-13.
2012: Ruth McNerney; Ziad Memish; Giovanni-Batista Migliori; Peter Mwaba; Justin O'Grady; Giuseppe Pantaleo; Michel Pletschette; Marco Schito; Samana Schwank; S Bertel Squire; Soumya Swaminathan; Karin Weyer; Lynn Zijenah; Ibrahim Abubakar; Rifat Atun; Matthew Bates; Martina Casenghi; JM Chakaya; Helen Cox; Lucica Ditui; Nathan Ford; Martin P Grobusch; Alexandre Harari; Michael Hoelscher; Peter S Kim; Stephen D Lawn; Markus Maeurer; Ben Marais; Timothy D McHugh; Alimuddin Zumla
Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities.
The Journal of infectious diseases 2012;205 Suppl 2():S147-58.
2012: Alimuddin Zumla; Ibrahim Abubakar; JM Chakaya; Helen Cox; Lucica Ditiu; Nathan Ford; Martin P Grobusch; Michael Hoelscher; Stephen D Lawn; Markus Maeurer; Ben Marais; Timothy D McHugh; Ruth McNerney; Ziad Memish; Giovanni-Battista Migliori; Peter Mwaba; Justin O'Grady; Michel Pletschette; Andrew Ramsay; Mario C Raviglione; Marco Schito; S Bertel Squire; Soumya Swaminathan; Rifat Atun
Drug-resistant tuberculosis--current dilemmas, unanswered questions, challenges, and priority needs.
The Journal of infectious diseases 2012;205 Suppl 2():S228-40.
2012: Michael Uhlin; Alimuddin Zumla; Jan Andersson; Markus Maeurer
Adjunct immunotherapies for tuberculosis.
The Journal of infectious diseases 2012;205 Suppl 2():S325-34.
2012: Yoko Akachi; Alimuddin Zumla; Rifat Atun
Investing in improved performance of national tuberculosis programs reduces the tuberculosis burden: analysis of 22 high-burden countries, 2002-2009.
The Journal of infectious diseases 2012;205 Suppl 2():S284-92.
2012: Patrick P J Phillips; Michel Pletschette; Alimuddin Zumla; Rob Aarnoutse; Martin Boeree; Stephen H Gillespie; Richard Hafner; Norbert Heinrich; Christian Lienhardt; Tim McHugh; Charles Mgone; Andrew J Nunn; Michael Hoelscher
Innovative trial designs are practical solutions for improving the treatment of tuberculosis.
The Journal of infectious diseases 2012;205 Suppl 2():S250-7.
2012: Donna Lee; Alimuddin Zumla; Ryuichi Komatsu; S S Lal; Rifat Atun
Global fund financing of tuberculosis services delivery in prisons.
The Journal of infectious diseases 2012;205 Suppl 2():S274-83.
2012: Ibrahim Abubakar; Ted Cohen; Punam Mangtani; Laura Pimpin; Laura C Rodrigues; S Bertel Squire; Helen R Stagg; John M Watson; Alimuddin Zumla
Controversies and unresolved issues in tuberculosis prevention and control: a low-burden-country perspective.
The Journal of infectious diseases 2012;205 Suppl 2():S293-300.
2012: Victor Mudenda; Peter Mwaba; Justin O'Grady; Samana Schwank; Aaron Shibemba; Rifat Atun; Matthew Bates; Michael Hoelscher; Nathan Kapata; Sebastian Lucas; Markus Maeurer; Alimuddin Zumla
Tuberculosis and tuberculosis/HIV/AIDS-associated mortality in Africa: the urgent need to expand and invest in routine and research autopsies.
The Journal of infectious diseases 2012;205 Suppl 2():S340-6.
2012: Christian Lienhardt; Mario C Raviglione; Mel Spigelman; Alimuddin Zumla; Richard Hafner; Michael Hoelscher; Ernesto Jaramillo; Jan Gheuens
New drugs for the treatment of tuberculosis: needs, challenges, promise, and prospects for the future.
The Journal of infectious diseases 2012;205 Suppl 2():S241-9.
2012: Rebecca Axelsson-Robertson; Isabelle Magalhaes; Shreemanta K Parida; Alimuddin Zumla; Markus Maeurer
The immunological footprint of Mycobacterium tuberculosis T-cell epitope recognition.
The Journal of infectious diseases 2012;205 Suppl 2():S301-15.
2012: Alimuddin Zumla; Rifat Atun; Richard Hafner; Patrick Jean-Philippe; Peter S Kim; Markus Maeurer; Marco Schito
Eliminating tuberculosis and tuberculosis-HIV co-disease in the 21st century: key perspectives, controversies, unresolved issues, and needs.
The Journal of infectious diseases 2012;205 Suppl 2():S141-6.
2012: Alimuddin Zumla; Markus Maeurer
Rational development of adjunct immune-based therapies for drug-resistant tuberculosis: hypotheses and experimental designs.
The Journal of infectious diseases 2012;205 Suppl 2():S335-9.
2012: Christof Geldmacher; Alimuddin Zumla; Michael Hoelscher
Interaction between HIV and Mycobacterium tuberculosis: HIV-1-induced CD4 T-cell depletion and the development of active tuberculosis.
Current opinion in HIV and AIDS 2012;7(3):268-75.
2012: Athar Haroon; Alimuddin Zumla; Jamshed Bomanji
Role of fluorine 18 fluorodeoxyglucose positron emission tomography-computed tomography in focal and generalized infectious and inflammatory disorders.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012;54(9):1333-41.
2012: Ian Cummings; Shyam Kolvekar; Justin O'Grady; Vasudev Pai; Alimuddin Zumla
Surgery and tuberculosis.
Current opinion in pulmonary medicine 2012;18(3):241-5.
2012: Giovanni Ferrara; Markus Maeurer; Giovanni Battista Migliori; Megan Murray; Giovanni Sotgiu; Kevin Winthrop; Rosella Centis; Alimuddin Zumla
Risk factors associated with pulmonary tuberculosis: smoking, diabetes and anti-TNFα drugs.
Current opinion in pulmonary medicine 2012;18(3):233-40.
2012: Alimuddin Zumla
Killer respiratory tract infections: time to turn the tide.
Current opinion in pulmonary medicine 2012;18(3):173-4.
2012: Alimuddin Zumla; Frank Cobelens
Operational research and MDG tuberculosis control targets.
The Lancet infectious diseases 2012;12(4):262-3.
2012: Mario Raviglione; Alimuddin Zumla; Richard Horton; Ben Marais; Aaron Motsoaledi
A sustainable agenda for tuberculosis control and research.
Lancet 2012;379(9821):1077-8.
2012: Alimuddin Zumla; Richard Hafner; Michael Hoelscher; Christian Lienhardt; Andrew Nunn
Advancing the development of tuberculosis therapy.
Nature reviews. Drug discovery 2012;11(3):171-2.
2012: Gwinyai Masukume; Alimuddin Zumla
Analogies and metaphors in clinical medicine.
Clinical medicine (London, England) 2012;12(1):55-6.
2012: Ibrahim Abubakar; Masoud Dara; Davide Manissero; Alimuddin Zumla
Tackling the spread of drug-resistant tuberculosis in Europe.
Lancet 2012;379(9813):e21-3.
2012: Matthew Bates; Busiku Cheelo; Moses Chilufya; Lophina Chilukutu; Mumba Chomba; Petra Clowes; Michael Hoelscher; Nathan Kapata; Markus Maeurer; Lukundo Mukonda; Maxwell Mumba; Peter Mwaba; Judith Mzyece; Justin O'Grady; Andrea Rachow; John Tembo; Alimuddin Zumla
Evaluation of the burden of unsuspected pulmonary tuberculosis and co-morbidity with non-communicable diseases in sputum producing adult inpatients.
PloS one 2012;7(7):e40774.
2012: Alimuddin Zumla
The Global Fund Round 11 cancellation fiasco: turning disaster into opportunity?
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2012;16(3):285-6.
2012: Raija K Ahmed; Kithiganahalli N Balaji; Hans Gaines; Sven E Hoffner; Isabelle Magalhaes; Zoyia Rohava; Alena Skrahina; Alimuddin Zumla; Markus J Maeurer
Pattern recognition and cellular immune responses to novel Mycobacterium tuberculosis-antigens in individuals from Belarus.
BMC infectious diseases 2012;12():41.
2011: Nathan Kapata; Victor Mukonka; Mathew Bates; Pascalina Chanda-Kapata; Justin O'Grady; Samana Schwank; Alimuddin Zumla; Peter Mwaba
Trends of Zambia's tuberculosis burden over the past two decades.
Tropical medicine & international health : TM & IH 2011;16(11):1404-9.
2011: J O'Grady; I Abubakar; R Atun; M Bates; G Ferrara; Michael Hoelscher; N Kapata; M Maeurer; Peter Mwaba; Alimuddin Zumla
Tuberculosis in prisons: anatomy of global neglect.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2011;38(4):752-4.
2011: Giovanni Ferrara; Justin O'Grady; Alimuddin Zumla; Markus Maeurer
Xpert MTB/RIF test for tuberculosis.
Lancet 2011;378(9790):482; author reply 482-3.
2011: Fulvio Salvo; Alimuddin Zumla; Giovanni Battista Migliori; Tsetan Dorjee Sadutshang; Daniela Maria Cirillo
Xpert MTB/RIF test for tuberculosis.
Lancet 2011;378(9790):481-2; author reply 482-3.
2011: Ruth McNerney; Justin O'Grady; Giovanni Ferrara; Markus Maeurer; Alimuddin Zumla
Screening of immigrants in the UK for latent tuberculosis.
Expert review of respiratory medicine 2011;5(4):483-6.
2011: Peter Mwaba; Justin O'Grady; Matthew Bates; Martin Peter Grobusch; Nathan Kapata; Markus Maeurer; Ruth McNerney; Alimuddin Zumla
Achieving STOP TB Partnership goals: perspectives on development of new diagnostics, drugs and vaccines for tuberculosis.
Tropical medicine & international health : TM & IH 2011;16(7):819-27.
2011: Giovanni Ferrara; Shreemanta K Parida; Luca Richeldi; Alimuddin Zumla; Markus Maeurer
A decade of interferon-γ release assays: quest for the holy grail to diagnose latent infection with mycobacterium tuberculosis?
American journal of respiratory and critical care medicine 2011;183(12):1732.
2011: Justin O'Grady; Peter Mwaba; Alimuddin Zumla
The health of prisoners.
Lancet 2011;377(9782):2001.
2011: Gerhard Walzl; Katharina Ronacher; Willem A Hanekom; Thomas J Scriba; Alimuddin Zumla
Immunological biomarkers of tuberculosis.
Nature reviews. Immunology 2011;11(5):343-54.
2011: Justin O'Grady; Markus Maeurer; Peter Mwaba; Nathan Kapata; Matthew Bates; Michael Hoelscher; Alimuddin Zumla
New and improved diagnostics for detection of drug-resistant pulmonary tuberculosis.
Current opinion in pulmonary medicine 2011;17(3):134-41.
2011: Alimuddin Zumla
Pulmonary infections: 'le terrain est tout, le microbe n'est rien'.
Current opinion in pulmonary medicine 2011;17(3):131-3.
2011: Jamshed Bomanji; Ahmad Almuhaideb; Alimuddin Zumla
Combined PET and X-ray computed tomography imaging in pulmonary infections and inflammation.
Current opinion in pulmonary medicine 2011;17(3):197-205.
2011: John M Wrightson; Najib M Rahman; Tanya Novak; Jim F Huggett; nick maskell; Alimuddin Zumla; Robert F Miller; Robert J O Davies
Pneumocystis jirovecii in pleural infection: a nucleic acid amplification study.
Thorax 2011;66(5):450-1.
2011: Alimuddin Zumla; Wing Wai Yew
New tools for achieving tuberculosis control: progress and reflexion.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2011;15(3):285-6.
2011: Justin O'Grady; Michael Hoelscher; Rifat Atun; Matthew Bates; Peter Mwaba; Nathan Kapata; Giovanni Ferrara; Markus Maeurer; Alimuddin Zumla
Tuberculosis in prisons in sub-Saharan Africa--the need for improved health services, surveillance and control.
Tuberculosis (Edinburgh, Scotland) 2011;91(2):173-8.
2011: Justin O'Grady; Matthew Bates; Nathan Kapata; Peter Mwaba; Alimuddin Zumla
Tuberculosis in prisons in sub-Saharan Africa--a potential time bomb.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2011;101(2):107-8.
2011: Andrea Rachow; Klaus Reither; Gabriel Rojas-Ponce; Elmar Saathoff; Alimuddin Zumla; Catharina Boehme; Keertan Dheda; Norbert Heinrich; Jim Huggett; Bariki Mtafya; Elias N Ntinginya; Justin O'Grady; Mark Perkins; Michael Hoelscher
Rapid and accurate detection of Mycobacterium tuberculosis in sputum samples by Cepheid Xpert MTB/RIF assay--a clinical validation study.
PloS one 2011;6(6):e20458.
2011: Alimuddin Zumla; Rifat Atun; Markus Maeurer; Peter Mwaba; Zhenkun Ma; Justin O'Grady; Matthew Bates; Keertan Dheda; Michael Hoelscher; John Grange
Viewpoint: Scientific dogmas, paradoxes and mysteries of latent Mycobacterium tuberculosis infection.
Tropical medicine & international health : TM & IH 2011;16(1):79-83.
2011: Markos Abebe; Louise Kim; Graham Rook; Abraham Aseffa; Liya Wassie; Martha Zewdie; Alimuddin Zumla; Howard Engers; Peter Andersen; T Mark Doherty
Modulation of cell death by M. tuberculosis as a strategy for pathogen survival.
Clinical & developmental immunology 2011;2011():678570.
2011: Alimuddin Zumla
The white plague returns to London--with a vengeance.
Lancet 2011;377(9759):10-1.
2010: Alimuddin Zumla; John M Grange
Is the eradication of tuberculosis 'yesterday's ambition' or 'tomorrow's triumph'?
Clinical medicine (London, England) 2010;10(5):450-3.
2010: Julie Jarand; Karen Shean; Max R. O'Donnell; Marian Loveday; Charlotte Kvasnovsky; Martie Van der Walt; Shahieda Adams; Paul A Willcox; Justin O'Grady; Alimuddin Zumla; Keertan Dheda
Extensively drug-resistant tuberculosis (XDR-TB) among health care workers in South Africa.
Tropical medicine & international health : TM & IH 2010;15(10):1179-84.
2010: Rifat A Atun; Mario Raviglione; Ben Marais; Alimuddin Zumla
Tuberculosis control is crucial to achieve the MDGs.
Lancet 2010;376(9745):940-1.
2010: José A Caminero; Giovanni Sotgiu; Alimuddin Zumla; Giovanni Battista Migliori
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
The Lancet infectious diseases 2010;10(9):621-9.
2010: Keertan Dheda; Robin M Warren; Alimuddin Zumla; Martin P Grobusch
Extensively drug-resistant tuberculosis: epidemiology and management challenges.
Infectious disease clinics of North America 2010;24(3):705-25.
2010: Alimuddin Zumla; Wing Wai Yew; David S C Hui
Emerging respiratory infections in the 21st century. Preface.
Infectious disease clinics of North America 2010;24(3):xiii-xvi.
2010: Giovanni Battista Migliori; Peter Mwaba; Justin O'Grady; Matthew Bates; Rosella Centis; Keertan Dheda; Michael Hoelscher; Alimuddin Zumla
Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa.
Tropical medicine & international health : TM & IH 2010;15(9):1052-66.
2010: Vinod B Patel; Ravesh Singh; Cathy Connolly; yacoob coovadia; Abdool K C Peer; Priyashini Parag; Victoria Kasprowicz; Alimuddin Zumla; Thumbi Ndung'u; Keertan Dheda
Cerebrospinal T-cell responses aid in the diagnosis of tuberculous meningitis in a human immunodeficiency virus- and tuberculosis-endemic population.
American journal of respiratory and critical care medicine 2010;182(4):569-77.
2010: Niaina Rakotosamimanana; Vaomalala Raharimanga; Soa Fy Andriamandimby; Jean-Louis Soares; Timothy Doherty; Maherisoa Ratsitorahina; Herimanana Ramarokoto; Alimuddin Zumla; Jim Huggett; Graham Rook; Vincent Richard; Brigitte Gicquel; Voahangy Rasolofo Razanamparany
Variation in gamma interferon responses to different infecting strains of Mycobacterium tuberculosis in acid-fast bacillus smear-positive patients and household contacts in Antananarivo, Madagascar.
Clinical and vaccine immunology : CVI 2010;17(7):1094-103.
2010: Ben J Marais; Mario C Raviglione; Peter R Donald; Anthony D Harries; Afranio L Kritski; Stephen M Graham; Wafaa M El-Sadr; Mark Harrington; Gavin Churchyard; Peter Mwaba; Ian Sanne; Stefan H E Kaufmann; Christopher J M Whitty; Rifat A Atun; Alimuddin Zumla
Scale-up of services and research priorities for diagnosis, management, and control of tuberculosis: a call to action.
Lancet 2010;375(9732):2179-91.
2010: Peter Mwaba; M Bates; C Green; N Kapata; Alimuddin Zumla
Research capacity strengthening in African countries.
Lancet 2010;375(9729):1874.
2010: Robert S Wallis; Madhukar Pai; Dick Menzies; Timothy Doherty; Gerhard Walzl; Mark Perkins; Alimuddin Zumla
Biomarkers and diagnostics for tuberculosis: progress, needs, and translation into practice.
Lancet 2010;375(9729):1920-37.
2010: Keertan Dheda; Karen Shean; Alimuddin Zumla; Motasim Badri; Elizabeth M Streicher; Liesl Page-Shipp; Paul A Willcox; Melanie-Anne John; Gary Reubenson; Darshini Govindasamy; Michelle Wong; Xavier Padanilam; Alicia Dziwiecki; Paul D van Helden; Sweetness Siwendu; Julie Jarand; Colin Nigel Menezes; Avril Burns; Thomas Victor; Robin Warren; Martin P Grobusch; Martie van der Walt; Charlotte Kvasnovsky
Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study.
Lancet 2010;375(9728):1798-807.
2010: Robin Fears; Stefan Kaufmann; Volker Ter Meulen; Alimuddin Zumla
Drug-resistant tuberculosis in the European Union: opportunities and challenges for control.
Tuberculosis (Edinburgh, Scotland) 2010;90(3):182-7.
2010: Jonathan Peter; Clare Green; Michael Hoelscher; Peter Mwaba; Alimuddin Zumla; Keertan Dheda
Urine for the diagnosis of tuberculosis: current approaches, clinical applicability, and new developments.
Current opinion in pulmonary medicine 2010;16(3):262-70.
2010: Simon F Lee; David Lawrence; Helen Booth; Stephen Morris-Jones; Bruce Macrae; Alimuddin Zumla
Thoracic empyema: current opinions in medical and surgical management.
Current opinion in pulmonary medicine 2010;16(3):194-200.
2010: Alimuddin Zumla
The relentless and persistent global threat of a range of pulmonary infections.
Current opinion in pulmonary medicine 2010;16(3):169-70.
2010: L M Lenders; R Meldau; Roal van Zyl-Smit; V Woodburne; A Maredza; T J Cashmore; P L Semple; Motasim Badri; Alimuddin Zumla; Keertan Dheda
Comparison of same day versus delayed enumeration of TB-specific T cell responses.
The Journal of infection 2010;60(5):344-50.
2010: Ben Marais; Michael Hoelscher; Peter Mwaba; Keertan Dheda; Alimuddin Zumla
World TB Day 2010: eradicating tuberculosis in sub-Saharan Africa needs effective and committed north-south partnerships.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2010;100(3):153-4.
2010: John Grange; Miriam Adhikari; Yusuf Ahmed; Peter Mwaba; Keertan Dheda; Michael Hoelscher; Alimuddin Zumla
Tuberculosis in association with HIV/AIDS emerges as a major nonobstetric cause of maternal mortality in Sub-Saharan Africa.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2010;108(3):181-3.
2010: Yusuf Ahmed; Peter Mwaba; John Grange; Clare Green; Alimuddin Zumla
Community-based interventions to reduce maternal mortality.
Lancet 2010;375(9713):457-8; author reply 458-9.
2010: Robert S Wallis; Cunshan Wang; Timothy Doherty; Phillip Onyebujoh; Mahnaz Vahedi; Hannu Laang; Ole Olesen; Shreemanta Parida; Alimuddin Zumla
Biomarkers for tuberculosis disease activity, cure, and relapse.
The Lancet infectious diseases 2010;10(2):68-9.
2010: Päivi Tissari; Alimuddin Zumla; Eveliina Tarkka; Sointu Mero; Laura Savolainen; Martti Vaara; Anne Aittakorpi; Sanna Laakso; Merja Lindfors; Heli Piiparinen; Minna Mäki; Caroline Carder; Jim Huggett; Vanya Gant
Accurate and rapid identification of bacterial species from positive blood cultures with a DNA-based microarray platform: an observational study.
Lancet 2010;375(9710):224-30.
2010: Tamaryn J Cashmore; Jonathan G Peter; Roal van Zyl-Smit; Patricia L Semple; Alice Maredza; Richard Meldau; Alimuddin Zumla; Barbara Nurse; Keertan Dheda
Feasibility and diagnostic utility of antigen-specific interferon-gamma responses for rapid immunodiagnosis of tuberculosis using induced sputum.
PloS one 2010;5(4):e10389.
2010: Keertan Dheda; Virginia Davids; Laura Lenders; Teri Roberts; Richard Meldau; Daphne Ling; Laurence Brunet; Roal van Zyl-Smit; Jonathan Peter; Clare Green; Motasim Badri; Leonardo Sechi; Surendra Sharma; Michael Hoelscher; Rodney Dawson; Andrew Whitelaw; Jonathan Blackburn; Madhukar Pai; Alimuddin Zumla
Clinical utility of a commercial LAM-ELISA assay for TB diagnosis in HIV-infected patients using urine and sputum samples.
PloS one 2010;5(3):e9848.
2010: Anil Pooran; Helen Booth; Robert F Miller; Geoff Scott; Motasim Badri; Jim F Huggett; Graham Rook; Alimuddin Zumla; Keertan Dheda
Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis.
BMC pulmonary medicine 2010;10():7.
2010: Roal van Zyl-Smit; M Pai; W W Yew; C C Leung; Alimuddin Zumla; Eric D Bateman; Keertan Dheda
Global lung health: the colliding epidemics of tuberculosis, tobacco smoking, HIV and COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;35(1):27-33.
2010: Markos Abebe; T Mark Doherty; Liya Wassie; Abraham Aseffa; Kidist Bobosha; Abebech Demissie; Martha Zewdie; Howard Engers; Peter Andersen; Louise Kim; Jim Huggett; Graham Rook; Lawrence K Yamuah; Alimuddin Zumla
Expression of apoptosis-related genes in an Ethiopian cohort study correlates with tuberculosis clinical status.
European journal of immunology 2010;40(1):291-301.
2009: Nina Witt; Gillian Rodger; Jo Vandesompele; Vladimir Benes; Alimuddin Zumla; Graham Rook; Jim F Huggett
An assessment of air as a source of DNA contamination encountered when performing PCR.
Journal of biomolecular techniques : JBT 2009;20(5):236-40.
2009: T Mark Doherty; Robert S Wallis; Alimuddin Zumla
Biomarkers of disease activity, cure, and relapse in tuberculosis.
Clinics in chest medicine 2009;30(4):783-96, x.
2009: Alimuddin Zumla; H Simon Schaaf
Tuberculosis. Preface.
Clinics in chest medicine 2009;30(4):xiii-xviii.
2009: Keertan Dheda; Roal van Zyl-Smit; Leonardo A Sechi; Motasim Badri; R Meldau; S Meldau; G Symons; P L Semple; A Maredza; R Dawson; Helen Wainwright; A Whitelaw; Y Vallie; P Raubenheimer; Eric D Bateman; Alimuddin Zumla
Utility of quantitative T-cell responses versus unstimulated interferon-{gamma} for the diagnosis of pleural tuberculosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2009;34(5):1118-26.
2009: Keertan Dheda; Roal van Zyl-Smit; R Meldau; S Meldau; G Symons; H Khalfey; N Govender; V Rosu; Leonardo A Sechi; A Maredza; P Semple; A Whitelaw; Helen Wainwright; Motasim Badri; R Dawson; Eric D Bateman; Alimuddin Zumla
Quantitative lung T cell responses aid the rapid diagnosis of pulmonary tuberculosis.
Thorax 2009;64(10):847-53.
2009: Robin Fears; Alimuddin Zumla; Volker ter Meulen
European bodies can help to tackle TB worldwide.
Nature 2009;460(7257):796.
2009: Clare Green; Jim Huggett; Elizabeth Talbot; Peter Mwaba; Klaus Reither; Alimuddin Zumla
Rapid diagnosis of tuberculosis through the detection of mycobacterial DNA in urine by nucleic acid amplification methods.
The Lancet infectious diseases 2009;9(8):505-11.
2009: Richard N van Zyl-Smit; Madhukar Pai; Kwaku Peprah; Richard Meldau; Jackie Kieck; June Juritz; Motasim Badri; Alimuddin Zumla; Leonardo A Sechi; Eric D Bateman; Keertan Dheda
Within-subject variability and boosting of T-cell interferon-gamma responses after tuberculin skin testing.
American journal of respiratory and critical care medicine 2009;180(1):49-58.
2009: Bruno Gryseels; Alimuddin Zumla; Marita Troye-Blomberg; Marie Paule Kieny; Gianluca Quaglio; Andreas Holtel; Hannu Laang; Manuel Romaris; Maria Teresa De Magistris; Ana Nieto Nuez; Ole F Olesen; Rachida Ghalouci; Anna Lönnroth
European Union conference on poverty-related diseases research.
The Lancet infectious diseases 2009;9(6):334-7.
2009: Mark Doherty; Robert Wallis; Alimuddin Zumla
Biomarkers for tuberculosis disease status and diagnosis.
Current opinion in pulmonary medicine 2009;15(3):181-7.
2009: Alimuddin Zumla
Editorial: emerging respiratory infections in the 21st century.
Current opinion in pulmonary medicine 2009;15(3):179-80.
2009: Jim Huggett; Clare Green; Alimuddin Zumla
Nucleic acid detection and quantification in the developing world.
Biochemical Society transactions 2009;37(Pt 2):419-23.
2009: Alimuddin Zumla; Peter Mwaba; Jim Huggett; Nathan Kapata; Duncan Chanda; John Grange
Reflections on the white plague.
The Lancet infectious diseases 2009;9(3):197-202.
2009: Robert Wallis; Timothy Doherty; Phillip Onyebujoh; Mahnaz Vahedi; Hannu Laang; Ole Olesen; Shreemanta Parida; Alimuddin Zumla
Biomarkers for tuberculosis disease activity, cure, and relapse.
The Lancet infectious diseases 2009;9(3):162-72.
2009: Graham Rook; Rogelio Hernández Pando; Alimuddin Zumla
Tuberculosis due to high-dose challenge in partially immune individuals: a problem for vaccination?
The Journal of infectious diseases 2009;199(5):613-8.
2009: John M Grange; Nathan Kapata; Duncan Chanda; Peter Mwaba; Alimuddin Zumla
The biosocial dynamics of tuberculosis.
Tropical medicine & international health : TM & IH 2009;14(2):124-30.
2009: Keertan Dheda; Richard N Van-Zyl Smit; Leonardo A Sechi; Motasim Badri; Richard Meldau; Gregory Symons; Hoosein Khalfey; Igshaan Carr; Alice Maredza; Rodney Dawson; Helen Wainright; Andrew Whitelaw; Eric D Bateman; Alimuddin Zumla
Clinical diagnostic utility of IP-10 and LAM antigen levels for the diagnosis of tuberculous pleural effusions in a high burden setting.
PloS one 2009;4(3):e4689.
2008: Alimuddin Zumla
Current opinions on selected respiratory infections causing global morbidity and mortality.
Current opinion in pulmonary medicine 2008;14(3):165-7.
2008: Alimuddin Zumla
Tuberculosis--the tide can be turned, the battle can be won.
Journal of the Royal Society of Medicine 2008;101(3):100-1.
2008: Gillian M Craig; Helen Booth; Jo Hall; Alistair Story; Andrew Hayward; Ann Goodburn; Alimuddin Zumla
Establishing a new service role in tuberculosis care: the tuberculosis link worker.
Journal of advanced nursing 2008;61(4):413-24.
2008: Jim Huggett; Martin Taylor; Gabrijela Kocjan; H E Evans; S Morris-Jones; Vanya Gant; T Novak; A M Costello; Alimuddin Zumla; Robert F Miller
Development and evaluation of a real-time PCR assay for detection of Pneumocystis jirovecii DNA in bronchoalveolar lavage fluid of HIV-infected patients.
Thorax 2008;63(2):154-9.
2008: Jim F Huggett; Tanya Novak; Jeremy A Garson; Clare Green; Stephen D Morris-Jones; Robert F Miller; Alimuddin Zumla
Differential susceptibility of PCR reactions to inhibitors: an important and unrecognised phenomenon.
BMC research notes 2008;1():70.
2008: Andrew J Nunn; Peter Mwaba; Chifumbe Chintu; Alwyn Mwinga; Janet H Darbyshire; Alimuddin Zumla
Role of co-trimoxazole prophylaxis in reducing mortality in HIV infected adults being treated for tuberculosis: randomised clinical trial.
BMJ (Clinical research ed.) 2008;337():a257.
2008: Liya Wassie; Abebech Demissie; Abraham Aseffa; Markos Abebe; Lawrence K Yamuah; Hiwot Tilahun; Beyene Petros; Graham Rook; Alimuddin Zumla; Peter Andersen; T Mark Doherty
Ex vivo cytokine mRNA levels correlate with changing clinical status of ethiopian TB patients and their contacts over time.
PloS one 2008;3(1):e1522.
2007: I Ciglenecki; Judith R Glynn; Alwyn Mwinga; Bagrey Ngwira; Alimuddin Zumla; Paul E M Fine; A Nunn
Population differences in death rates in HIV-positive patients with tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2007;11(10):1121-8.
2007: K Dheda; A Pooran; M Pai; R F Miller; K Lesley; Helen Booth; G M Scott; A N Akbar; Alimuddin Zumla; Graham Rook
Interpretation of Mycobacterium tuberculosis antigen-specific IFN-gamma release assays (T-SPOT.TB) and factors that may modulate test results.
The Journal of infection 2007;55(2):169-73.
2007: G M Craig; Helen Booth; Alistair Story; Andrew Hayward; J Hall; A Goodburn; Alimuddin Zumla
The impact of social factors on tuberculosis management.
Journal of advanced nursing 2007;58(5):418-24.
2007: Chris Griffiths; Pat Sturdy; Penny Brewin; Graham Bothamley; Sandra Eldridge; Adrian Martineau; Meg MacDonald; Jean Ramsay; Suresh Tibrewal; Sue Levi; Alimuddin Zumla; Gene Feder
Educational outreach to promote screening for tuberculosis in primary care: a cluster randomised controlled trial.
Lancet 2007;369(9572):1528-34.
2007: Keertan Dheda; Jung-Su Chang; Jim Huggett; Louise U Kim; Margaret A Johnson; Alimuddin Zumla; Graham Rook
The stability of mRNA encoding IL-4 is increased in pulmonary tuberculosis, while stability of mRNA encoding the antagonistic splice variant, IL-4delta2, is not.
Tuberculosis (Edinburgh, Scotland) 2007;87(3):237-41.
2007: Veronica Mulenga; Deborah Ford; A Sarah Walker; Darlington Mwenya; James Mwansa; Frederick Sinyinza; Kennedy Lishimpi; Andrew Nunn; Stephen Gillespie; Alimuddin Zumla; Chifumbe Chintu; Diana M Gibb
Effect of cotrimoxazole on causes of death, hospital admissions and antibiotic use in HIV-infected children.
AIDS (London, England) 2007;21(1):77-84.
2007: Sanjay Lala; Keertan Dheda; Jung-Su Chang; Jim Huggett; Louise U Kim; Margaret A Johnson; Graham Rook; Satish Keshav; Alimuddin Zumla
The pathogen recognition sensor, NOD2, is variably expressed in patients with pulmonary tuberculosis.
BMC infectious diseases 2007;7():96.
2006: Jung-Su Chang; Keertan Dheda; Jim Huggett; Louise U Kim; Alimuddin Zumla; Graham Rook
Expression of IL-4 mRNA in peripheral blood mononuclear cells from normal donors in relation to expression of TLR2.
Immunology letters 2006;106(2):194-7.
2006: Abebech Demissie; Liya Wassie; Markos Abebe; Abraham Aseffa; Graham Rook; Alimuddin Zumla; Peter Andersen; T Mark Doherty
The 6-kilodalton early secreted antigenic target-responsive, asymptomatic contacts of tuberculosis patients express elevated levels of interleukin-4 and reduced levels of gamma interferon.
Infection and immunity 2006;74(5):2817-22.
2006: Alimuddin Zumla
Infectious diseases.
Current opinion in pulmonary medicine 2006;12(3):165-6.
2006: Graham Rook; Keertan Dheda; Alimuddin Zumla
Immune systems in developed and developing countries; implications for the design of vaccines that will work where BCG does not.
Tuberculosis (Edinburgh, Scotland) 2006;86(3-4):152-62.
2006: Mark Perkins; Giorgio Roscigno; Alimuddin Zumla
Progress towards improved tuberculosis diagnostics for developing countries.
Lancet 2006;367(9514):942-3.
2006: Alimuddin Zumla; Zoë Mullan
Turning the tide against tuberculosis.
Lancet 2006;367(9514):877-8.
2006: Jung-Su Chang; Jim Huggett; Keertan Dheda; Louise U Kim; Alimuddin Zumla; Graham Rook
Myobacterium tuberculosis induces selective up-regulation of TLRs in the mononuclear leukocytes of patients with active pulmonary tuberculosis.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):3010-8.
2006: Abebech Demissie; Eliane M S Leyten; Markos Abebe; Liya Wassie; Abraham Aseffa; Getahun Abate; Helen Fletcher; Patrick K Owiafe; Philip C Hill; Roger H Brookes; Graham Rook; Alimuddin Zumla; Sandra M Arend; Michel Klein; Tom H M Ottenhoff; Peter Andersen; T Mark Doherty
Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis.
Clinical and vaccine immunology : CVI 2006;13(2):179-86.
2006: Jim Huggett; Robert F Miller; Martin Taylor; Anthony M Costello; Alimuddin Zumla
Problems of developing molecular diagnostic tests for opportunistic pathogens: the example of Pneumocystis jirovecii.
The Journal of eukaryotic microbiology 2006;53 Suppl 1():S85-6.
2006: Yankuba Kassama; Michael Shemko; Nandini Shetty; Zack Fang; Graham Macintire; Vanya Gant; Alimuddin Zumla; Royston Goodacre
An improved fluorescent amplified fragment length polymorphism method for typing Mycobacterium tuberculosis.
Journal of clinical microbiology 2006;44(1):288-9.
2005: Keertan Dheda; Ajit Lalvani; Robert F Miller; Geoff Scott; Helen Booth; Margaret A Johnson; Alimuddin Zumla; Graham Rook
Performance of a T-cell-based diagnostic test for tuberculosis infection in HIV-infected individuals is independent of CD4 cell count.
AIDS (London, England) 2005;19(17):2038-41.
2005: Philip Onyebujoh; Alimuddin Zumla; Isabela Ribeiro; Roxana Rustomjee; Peter Mwaba; Melba Gomes; John M Grange
Treatment of tuberculosis: present status and future prospects.
Bulletin of the World Health Organization 2005;83(11):857-65.
2005: Christian Lienhardt; Alimuddin Zumla
BCG: the story continues.
Lancet 2005;366(9495):1414-6.
2005: Keertan Dheda; Jung-Su Chang; Ronan A M Breen; Jamanda A Haddock; M C I Lipman; Louise U Kim; Jim Huggett; Margaret A Johnson; Graham Rook; Alimuddin Zumla
Expression of a novel cytokine, IL-4delta2, in HIV and HIV-tuberculosis co-infection.
AIDS (London, England) 2005;19(15):1601-6.
2005: Keertan Dheda; Helen Booth; Jim Huggett; Margaret A Johnson; Alimuddin Zumla; Graham Rook
Lung remodeling in pulmonary tuberculosis.
The Journal of infectious diseases 2005;192(7):1201-9.
2005: Keertan Dheda; Jim Huggett; Jung-Su Chang; Louise U Kim; Stephen Andrew Bustin; Margaret A Johnson; Graham Rook; Alimuddin Zumla
The implications of using an inappropriate reference gene for real-time reverse transcription PCR data normalization.
Analytical biochemistry 2005;344(1):141-3.
2005: Keertan Dheda; Jung-Su Chang; Ronan A M Breen; Louise U Kim; Jamanda A Haddock; Jim Huggett; Margaret A Johnson; Graham Rook; Alimuddin Zumla
In vivo and in vitro studies of a novel cytokine, interleukin 4delta2, in pulmonary tuberculosis.
American journal of respiratory and critical care medicine 2005;172(4):501-8.
2005: Graham Rook; Keertan Dheda; Alimuddin Zumla
Immune responses to tuberculosis in developing countries: implications for new vaccines.
Nature reviews. Immunology 2005;5(8):661-7.
2005: Keertan Dheda; Jung-Su Chang; Louise U Kim; Jim Huggett; Margaret A Johnson; Alimuddin Zumla; Graham Rook
Interferon gamma assays for tuberculosis.
The Lancet infectious diseases 2005;5(6):324-5; author reply 325-7.
2005: Jim Huggett; Keertan Dheda; Stephen Andrew Bustin; Alimuddin Zumla
Real-time RT-PCR normalisation; strategies and considerations.
Genes and immunity 2005;6(4):279-84.
2005: Alimuddin Zumla
Towards improving outcomes of fatal pulmonary infections.
Current opinion in pulmonary medicine 2005;11(3):187-8.
2005: Graham Rook; Keertan Dheda; Alimuddin Zumla
Do successful tuberculosis vaccines need to be immunoregulatory rather than merely Th1-boosting?
Vaccine 2005;23(17-18):2115-20.
2005: T Mark Doherty; Abebech Demissie; Dick Menzies; Peter Andersen; Graham Rook; Alimuddin Zumla
Effect of sample handling on analysis of cytokine responses to Mycobacterium tuberculosis in clinical samples using ELISA, ELISPOT and quantitative PCR.
Journal of immunological methods 2005;298(1-2):129-41.
2005: Masharip Atadzhanov; Alimuddin Zumla; Peter Mwaba
Study of familial Parkinson's disease in Russia, Uzbekistan, and Zambia.
Postgraduate medical journal 2005;81(952):117-21.
2004: Jim Huggett; Keertan Dheda; Alimuddin Zumla; Graham Rook
Crohn's disease and MAP.
Lancet 2004;364(9452):2178; author reply 2178-9.
2004: Chifumbe Chintu; G J Bhat; A Sarah Walker; Veronica Mulenga; Frederick Sinyinza; Kennedy Lishimpi; Laura Farrelly; N Kaganson; Alimuddin Zumla; S H Gillespie; Andrew Nunn; Diana M Gibb
Co-trimoxazole as prophylaxis against opportunistic infections in HIV-infected Zambian children (CHAP): a double-blind randomised placebo-controlled trial.
Lancet 2004;364(9448):1865-71.
2004: John L Johnson; A J Nunn; P B Fourie; L Peter Ormerod; Roy D Mugerwa; Alwyn Mwinga; Chifumbe Chintu; Bagrey Ngwira; Philip Onyebujoh; Alimuddin Zumla
Effect of Mycobacterium vaccae (SRL172) immunotherapy on radiographic healing in tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2004;8(11):1348-54.
2004: Keertan Dheda; Margaret A Johnson; Alimuddin Zumla; Graham Rook
Smoking is not beneficial for tuberculosis.
American journal of respiratory and critical care medicine 2004;170(7):821; author reply 821.
2004: Helen A Fletcher; Patrick K Owiafe; David J Jeffries; Philip Hill; Graham Rook; Alimuddin Zumla; T Mark Doherty; Roger H Brookes
Increased expression of mRNA encoding interleukin (IL)-4 and its splice variant IL-4delta2 in cells from contacts of Mycobacterium tuberculosis, in the absence of in vitro stimulation.
Immunology 2004;112(4):669-73.
2004: Andrew Tomkins; Alimuddin Zumla; Geoffrey Pasvol; Chris Curtis; Stephen Wright
Too hard on tropical medicine?
Lancet 2004;364(9428):23.
2004: Keertan Dheda; Jim Huggett; Stephen Andrew Bustin; Margaret A Johnson; Graham Rook; Alimuddin Zumla
Validation of housekeeping genes for normalizing RNA expression in real-time PCR.
BioTechniques 2004;37(1):112-4, 116, 118-9.
2004: Keertan Dheda; Graham Rook; Alimuddin Zumla
Peripheral T cell interferon-gamma responses and latent tuberculosis.
American journal of respiratory and critical care medicine 2004;170(1):97-8; author reply 98.
2004: Abebech Demissie; Markos Abebe; Abraham Aseffa; Graham Rook; Helen Fletcher; Alimuddin Zumla; Karin Weldingh; Inger Brock; Peter Andersen; T Mark Doherty
Healthy individuals that control a latent infection with Mycobacterium tuberculosis express high levels of Th1 cytokines and the IL-4 antagonist IL-4delta2.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):6938-43.
2004: Keertan Dheda; Jim Huggett; Louise U Kim; Alimuddin Zumla
Type 2 cytokines in respiratory syncytial virus bronchiolitis.
American journal of respiratory and critical care medicine 2004;169(10):1167-8; author reply 1168.
2004: Alimuddin Zumla
Infectious diseases.
Current opinion in pulmonary medicine 2004;10(3):157-8.
2003: Peter Mwaba; Sharon Cassol; Andrew Nunn; Rick Pilon; Chifumbe Chintu; Michelle Janes; Alimuddin Zumla
Whole blood versus plasma spots for measurement of HIV-1 viral load in HIV-infected African patients.
Lancet 2003;362(9401):2067-8.
2003: Peter Mwaba; Sharon Cassol; Rick Pilon; Chifumbe Chintu; Michelle Janes; Andrew Nunn; Alimuddin Zumla
Use of dried whole blood spots to measure CD4+ lymphocyte counts in HIV-1-infected patients.
Lancet 2003;362(9394):1459-60.
2003: Jim Huggett; Timothy D McHugh; Alimuddin Zumla
Tuberculosis: amplification-based clinical diagnostic techniques.
The international journal of biochemistry & cell biology 2003;35(10):1407-12.
2003: Alimuddin Zumla
Editorial overview: Infectious diseases.
Current opinion in pulmonary medicine 2003;9(3):163-5.
2003: Peter Mwaba; M Maboshe; Chifumbe Chintu; B Squire; S Nyirenda; R Sunkutu; Alimuddin Zumla
The relentless spread of tuberculosis in Zambia--trends over the past 37 years (1964-2000).
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 2003;93(2):149-52.
2002: Alwyn Mwinga; Andrew Nunn; Bagrey Ngwira; Chifumbe Chintu; David K Warndorff; Paul Fine; Janet Darbyshire; Alimuddin Zumla
Mycobacterium vaccae (SRL172) immunotherapy as an adjunct to standard antituberculosis treatment in HIV-infected adults with pulmonary tuberculosis: a randomised placebo-controlled trial.
Lancet 2002;360(9339):1050-5.
2002: Chifumbe Chintu; Victor Mudenda; Sebastian Lucas; Andrew Nunn; Kennedy Lishimpi; Daniel Maswahu; Francis Kasolo; Peter Mwaba; Ganapati Bhat; Hiroshi Terunuma; Alimuddin Zumla
Lung diseases at necropsy in African children dying from respiratory illnesses: a descriptive necropsy study.
Lancet 2002;360(9338):985-90.
2002: Matthew Gandy; Alimuddin Zumla
The resurgence of disease: social and historical perspectives on the 'new' tuberculosis.
Social science & medicine (1982) 2002;55(3):385-96; discussion 397-401.
2002: Alimuddin Zumla
Drugs for neglected diseases.
The Lancet infectious diseases 2002;2(7):393.
2002: John M Grange; Alimuddin Zumla
The global emergency of tuberculosis: what is the cause?
The journal of the Royal Society for the Promotion of Health 2002;122(2):78-81.
2002: Alimuddin Zumla; John Grange
Non-tuberculous mycobacterial pulmonary infections.
Clinics in chest medicine 2002;23(2):369-76.
2002: Alimuddin Zumla; D Geraint James
Immunologic aspects of tropical lung disease.
Clinics in chest medicine 2002;23(2):283-308, vii.
2002: Alimuddin Zumla; Anthony Costello
Ethics of healthcare research in developing countries.
Journal of the Royal Society of Medicine 2002;95(6):275-6.
2002: Alimuddin Zumla; John Grange
Infection and disease caused by environmental mycobacteria.
Current opinion in pulmonary medicine 2002;8(3):166-72.
2002: Kennedy Lishimpi; Francis Kasolo; Chifumbe Chintu; Peter Mwaba; Victor Mudenda; Daniel Maswahu; Hiroshi Terunuma; Helen Fletcher; Andrew Nunn; Sebastian Lucas; Alimuddin Zumla
Identification of Pneumocystis carinii DNA in oropharyngeal mouth washes from AIDS children dying of respiratory illnesses.
AIDS (London, England) 2002;16(6):932-4.
2002: Francis Kasolo; Kennedy Lishimpi; Chifumbe Chintu; Peter Mwaba; Victor Mudenda; Daniel Maswahu; Hiroshi Terunuma; Helen Fletcher; Andrew Nunn; Sebastian Lucas; Alimuddin Zumla
Identification of Pneumocystis carinii DNA by polymerase chain reaction in necropsy lung samples from children dying of respiratory tract illnesses.
The Journal of pediatrics 2002;140(3):367-9.
2001: Peter Mwaba; James Mwansa; Chifumbe Chintu; JO Pobee; M Scarborough; S Portsmouth; Alimuddin Zumla
Clinical presentation, natural history, and cumulative death rates of 230 adults with primary cryptococcal meningitis in Zambian AIDS patients treated under local conditions.
Postgraduate medical journal 2001;77(914):769-73.
2001: Kennedy Lishimpi; Chifumbe Chintu; Sebastian Lucas; Victor Mudenda; J Kaluwaji; Alistair Story; Daniel Maswahu; Ganapati Bhat; Andrew Nunn; Alimuddin Zumla
Necropsies in African children: consent dilemmas for parents and guardians.
Archives of disease in childhood 2001;84(6):463-7.
2001: John Grange; Alistair Story; Alimuddin Zumla
Tuberculosis in disadvantaged groups.
Current opinion in pulmonary medicine 2001;7(3):160-4.
2001: Graham Rook; Alimuddin Zumla
Advances in the immunopathogenesis of pulmonary tuberculosis.
Current opinion in pulmonary medicine 2001;7(3):116-23.
2001: J M Grange; Matthew Gandy; P Farmer; Alimuddin Zumla
Historical declines in tuberculosis: nature, nurture and the biosocial model.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2001;5(3):208-12.
2000: R W Baker; B R Walker; R J Shaw; John W Honour; D S Jessop; S L Lightman; Alimuddin Zumla; Graham Rook
Increased cortisol: cortisone ratio in acute pulmonary tuberculosis.
American journal of respiratory and critical care medicine 2000;162(5):1641-7.
2000: Richard Waddell; Chifumbe Chintu; AD Lein; Alimuddin Zumla; M R Karagas; KS Baboo; J D Habbema; Anna Tosteson; P Morin; Susan Tvaroha; Robert D Arbeit; Alwyn Mwinga; C Fordham von Reyn
Safety and immunogenicity of a five-dose series of inactivated Mycobacterium vaccae vaccination for the prevention of HIV-associated tuberculosis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;30 Suppl 3():S309-15.
2000: E T Tshibwabwa; Peter Mwaba; J Bogle-Taylor; Alimuddin Zumla
Four-year study of abdominal ultrasound in 900 Central African adults with AIDS referred for diagnostic imaging.
Abdominal imaging 2000;25(3):290-6.
2000: John M Grange; Alimuddin Zumla
Advances in the management of tuberculosis: clinical trials and beyond.
Current opinion in pulmonary medicine 2000;6(3):193-7.
2000: Alimuddin Zumla; P Malon; J Henderson; J M Grange
Impact of HIV infection on tuberculosis.
Postgraduate medical journal 2000;76(895):259-68.
1999: Y Ahmed; Peter Mwaba; Chifumbe Chintu; J M Grange; A Ustianowski; Alimuddin Zumla
A study of maternal mortality at the University Teaching Hospital, Lusaka, Zambia: the emergence of tuberculosis as a major non-obstetric cause of maternal death.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1999;3(8):675-80.
1999: J M Grange; Alimuddin Zumla
Paradox of the global emergency of tuberculosis.
Lancet 1999;353(9157):996.
1999: Alimuddin Zumla; S B Squire; Chifumbe Chintu; John M Grange
The tuberculosis pandemic: implications for health in the tropics.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1999;93(2):113-7.
1999: John Grange; Alimuddin Zumla
Tuberculosis and the poverty-disease cycle.
Journal of the Royal Society of Medicine 1999;92(3):105-7.
1999: Alimuddin Zumla; Peter Mwaba; S B Squire; John M Grange
The tuberculosis pandemic--which way now?
The Journal of infection 1999;38(2):74-9.
1999: Richard Waddell; C Fordham von Reyn; KS Baboo; Alwyn Mwinga; Chifumbe Chintu; Alimuddin Zumla
The effects of BCG immunization and human immunodeficiency virus infection on dual skin test reactions to purified protein derivative and Mycobacterium avium sensitin among adults in Zambia.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 1999;3(3):255-60.
1999: KS Baboo; NP Luo; JR Murphy; C Cummings; Chifumbe Chintu; A Ustianowski; HL DuPont; M Kelinowski; J J Mathewson; Alimuddin Zumla
HIV-1 seroprevalence in Zambian patients with acute diarrhea: a community-based study.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1999;20(2):160-3.
1998: Chifumbe Chintu; HL DuPont; T Kaile; M Mahmoud; S Marani; KS Baboo; W Mwansa; F Sakala-Kazembe; R Sunkutu; Alimuddin Zumla
Human immunodeficiency virus-associated diarrhea and wasting in Zambia: selected risk factors and clinical associations.
The American journal of tropical medicine and hygiene 1998;59(1):38-41.
1998: Alimuddin Zumla; John Grange
Tuberculosis.
BMJ (Clinical research ed.) 1998;316(7149):1962-4.
1998: Alimuddin Zumla; John Grange
Galloping consumption.
Nursing times 1998;94(14):14.
1997: John Grange; Alimuddin Zumla
Tuberculosis--an epidemic of injustice.
Journal of the Royal College of Physicians of London 1997;31(6):637-9.
1997: E Tshibwabwa-Tumba; Alwyn Mwinga; JO Pobee; Alimuddin Zumla
Radiological features of pulmonary tuberculosis in 963 HIV-infected adults at three Central African Hospitals.
Clinical radiology 1997;52(11):837-41.
1997: J M Grange; Alimuddin Zumla
Making DOTS succeed. Directly Observed Treatment, Short Course.
Lancet 1997;350(9072):157.
1997: Graham Rook; Alimuddin Zumla
Gulf War syndrome: is it due to a systemic shift in cytokine balance towards a Th2 profile?
Lancet 1997;349(9068):1831-3.
1996: N P Luo; KS Baboo; D Mwenya; A Diab; C U Perera; C Cummings; H L Dupont; JR Murphy; Alimuddin Zumla
Isolation of Campylobacter species from Zambian patients with acute diarrhoea.
East African medical journal 1996;73(6):395-6.
1995: Chifumbe Chintu; C Luo; S Baboo; B Khumalo-Ngwenya; John J Mathewson; H L DuPont; Alimuddin Zumla
Intestinal parasites in HIV-seropositive Zambian children with diarrhoea.
Journal of tropical pediatrics 1995;41(3):149-52.
1994: B Khumalo-Ngwenya; N P Luo; Chifumbe Chintu; R Sunkutu; F Sakala-Kazembe; KS Baboo; John J Mathewson; Alimuddin Zumla
Gut parasites in HIV-seropositive Zambian adults with diarrhoea.
East African medical journal 1994;71(6):379-83.
1994: H Oshitani; Francis Kasolo; M Mpabalwani; N P Luo; N Matsubayashi; G H Bhat; H Suzuki; Y Numazaki; Alimuddin Zumla; H L DuPont
Association of rotavirus and human immunodeficiency virus infection in children hospitalized with acute diarrhea, Lusaka, Zambia.
The Journal of infectious diseases 1994;169(4):897-900.
1993: Massimo Giangaspero; G Vacirca; D Morgan; KS Baboo; N P Luo; H L DuPont; Alimuddin Zumla
Anti-bovine viral diarrhoea virus antibodies in adult Zambian patients infected with the human immunodeficiency virus.
International journal of STD & AIDS 1993;4(5):300-2.
1991: N P Luo; C U Perera; Alimuddin Zumla
Salmonella septic arthritis.
The Journal of infection 1991;23(1):101.
1991: Alimuddin Zumla; D Savva; R B Wheeler; S K Hira; N P Luo; P Kaleebu; S K Sempala; J D Johnson; R Holliman
Toxoplasma serology in Zambian and Ugandan patients infected with the human immunodeficiency virus.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1991;85(2):227-9.
1990: Alimuddin Zumla; N P Luo
Surgery and Salmonella.
BMJ (Clinical research ed.) 1990;300(6735):1342.
1990: Alimuddin Zumla
Autoantibodies and tropical infections.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1990;84(1):162-5.