Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
Franco Zunino
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Chemicals & Drugs
Living Beings
Anatomy
Disorders
Physiology
Procedures
Concepts & Ideas
Sign-in to see full Profile
Network (preview)
77
Pratesi, Graziella
62
Perego, Paola
61
Supino, Rosanna
46
Capranico, Giovanni
35
De Cesare, Michelandrea
32
Carenini, Nives
25
Lanzi, Cinzia
21
Pisano, Claudio
20
Beretta, Giovanni Luca
19
Tortoreto, Monica
19
Zuco, Valentina
18
Merlini, Lucio
17
Righetti, Sabina
17
Dallavalle, Sabrina
17
Cassinelli, Giuliana
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of Franco Zunino (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Passarella Daniele; Comi Daniela; Vanossi Andrea; Paganini Gianfranco; Colombo Francesco; Ferrante Luca; Zuco Valentina; Danieli Bruno; Zunino Franco
Histone deacetylase and microtubules as targets for the synthesis of releasable conjugate compounds.
Bioorganic & medicinal chemistry letters 2009;19(22):6358-63.
-
2009: Cassinelli Giuliana; Ronchetti Domenica; Laccabue Diletta; Mattioli Michela; Cuccuru Giuditta; Favini Enrica; Nicolini Valentina; Greco Angela; Neri Antonino; Zunino Franco; Lanzi Cinzia
Concomitant downregulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells by multi-kinase targeting.
Biochemical pharmacology 2009;78(9):1139-47.
-
2009: Supino Rosanna; Scovassi A Ivana; Croce Anna Cleta; Dal Bo Laura; Favini Enrica; Corbelli Alessandro; Farina Carlo; Misiano Paola; Zunino Franco
Biological effects of a new vacuolar-H,-ATPase inhibitor in colon carcinoma cell lines.
Annals of the New York Academy of Sciences 2009;1171():606-16.
-
2009: Giommarelli Chiara; Corti Alessandro; Supino Rosanna; Favini Enrica; Paolicchi Aldo; Pompella Alfonso; Zunino Franco
Gamma-glutamyltransferase-dependent resistance to arsenic trioxide in melanoma cells and cellular sensitization by ascorbic acid.
Free radical biology & medicine 2009;46(11):1516-26.
-
2009: Dallavalle Sabrina; Cincinelli Raffaella; Nannei Raffaella; Merlini Lucio; Morini Gabriella; Penco Sergio; Pisano Claudio; Vesci Loredana; Barbarino Marcella; Zuco Valentina; De Cesare Michelandrea; Zunino Franco
Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors.
European journal of medicinal chemistry 2009;44(5):1900-12.
-
2009: Samorì Cristian; Guerrini Andrea; Varchi Greta; Beretta Giovanni Luca; Fontana Gabriele; Bombardelli Ezio; Carenini Nives; Zunino Franco; Bertucci Carlo; Fiori Jessica; Battaglia Arturo
The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates.
Bioconjugate chemistry 2009;20(3):629.
-
2009: Samorì Cristian; Guerrini Andrea; Varchi Greta; Fontana Gabriele; Bombardelli Ezio; Tinelli Stella; Beretta Giovanni Luca; Basili Serena; Moro Stefano; Zunino Franco; Battaglia Arturo
Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins.
Journal of medicinal chemistry 2009;52(4):1029-39.
-
2009: Lanzi Cinzia; Cassinelli Giuliana; Nicolini Valentina; Zunino Franco
Targeting RET for thyroid cancer therapy.
Biochemical pharmacology 2009;77(3):297-309.
-
2009: Scaglioni Leonardo; Mazzini Stefania; Mondelli Rosanna; Dallavalle Sabrina; Gattinoni Sonia; Tinelli Stella; Beretta Giovanni L; Zunino Franco; Ragg Enzio
Interaction between double helix DNA fragments and a new topopyrone acting as human topoisomerase I poison.
Bioorganic & medicinal chemistry 2009;17(2):484-91.
-
2009: Cossa Giacomo; Gatti Laura; Zunino Franco; Perego Paola
Strategies to improve the efficacy of platinum compounds.
Current medicinal chemistry 2009;16(19):2355-65.
-
2008: Gelmi Maria Luisa; Nava Donatella; Leone Samantha; Pellegrino Sara; Baldelli Eleonora; Zunino Franco; Cappelletti Graziella; Cartelli Daniele; Fontana Gabriele
Semisynthesis of new D-seco-C-nor-taxane derivatives containing a polyfunctionalized furanosyl or cyclopentenyl or cyclopentyl C-ring.
The Journal of organic chemistry 2008;73(22):8893-900.
-
2008: Samor Cristian; Guerrini Andrea; Varchi Greta; Beretta Giovanni Luca; Fontana Gabriele; Bombardelli Ezio; Carenini Nives; Zunino Franco; Bertucci Carlo; Fiori Jessica; Battaglia Arturo
The role of polyamine architecture on the pharmacological activity of open lactone camptothecin-polyamine conjugates.
Bioconjugate chemistry 2008;19(11):2270-9.
-
2008: Milli Alberto; Cecconi Daniela; Campostrini Natascia; Timperio Anna Maria; Zolla Lello; Righetti Sabina Carla; Zunino Franco; Perego Paola; Benedetti Valentina; Gatti Laura; Odreman Federico; Vindigni Alessandro; Righetti Pier Giorgio
A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cells.
Biochimica et biophysica acta 2008;1784(11):1702-10.
-
2008: Beretta Giovanni Luca; Perego Paola; Zunino Franco
Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors.
Expert opinion on therapeutic targets 2008;12(10):1243-56.
-
2008: De Cesare Michelandrea; Calcaterra Claudia; Pratesi Graziella; Gatti Laura; Zunino Franco; Mènard Sylvie; Balsari Andrea
Eradication of ovarian tumor xenografts by locoregional administration of targeted immunotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(17):5512-8.
-
2008: Beretta Giovanni L; Gatti Laura; Cesare Michelandrea De; Corna Elisabetta; Tinelli Stella; Carenini Nives; Zunino Franco; Perego Paola
The human homolog of fission yeast Rad17 is implicated in tumor growth.
Cancer letters 2008;266(2):194-202.
-
2008: Pisano Claudio; De Cesare Michelandrea; Beretta Giovanni Luca; Zuco Valentina; Pratesi Graziella; Penco Sergio; Vesci Loredana; Foderà Rosanna; Ferrara Fabiana Fosca; Guglielmi Mario Berardino; Carminati Paolo; Dallavalle Sabrina; Morini Gabriella; Merlini Lucio; Orlandi Augusto; Zunino Franco
Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.
Molecular cancer therapeutics 2008;7(7):2051-9.
-
2008: Pratesi Graziella; Petrangolini Giovanna; Tortoreto Monica; Addis Alessandro; Zunino Franco; Calcaterra Claudia; Merlo Andrea; Tagliabue Elda; Menard Sylvie; Balsari Andrea
Antitumor efficacy of trastuzumab in nude mice orthotopically xenografted with human pancreatic tumor cells expressing low levels of HER-2/neu.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(6):537-44.
-
2008: Beretta Giovanni Luca; Gatti Laura; Corna Elisabetta; Carenini Nives; Zunino Franco; Perego Paola
Defining targets of modulation of human tumor cell response to cisplatin.
Journal of inorganic biochemistry 2008;102(7):1406-15.
-
2008: Zuco Valentina; Zunino Franco
Cyclic pifithrin-alpha sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis.
Neoplasia (New York, N.Y.) 2008;10(6):587-96.
-
2008: Pisano Claudio; Zuco Valentina; De Cesare Michelandrea; Benedetti Valentina; Vesci Loredana; Foderà Rosanna; Bucci Federica; Aulicino Concetta; Penco Sergio; Carminati Paolo; Zunino Franco
Intracellular accumulation and DNA damage persistence as determinants of human squamous cell carcinoma hypersensitivity to the novel camptothecin ST1968.
European journal of cancer (Oxford, England : 1990) 2008;44(9):1332-40.
-
2008: Dallavalle Sabrina; Rocchetta Daniela Granza; Musso Loana; Merlini Lucio; Morini Gabriella; Penco Sergio; Tinelli Stella; Beretta Giovanni Luca; Zunino Franco
Synthesis and cytotoxic activity of new 9-substituted camptothecins.
Bioorganic & medicinal chemistry letters 2008;18(9):2781-7.
-
2008: Giannini Giuseppe; Marzi Mauro; Cabri Walter; Marastoni Elena; Battistuzzi Gianfranco; Vesci Loredana; Pisano Claudio; Beretta Giovanni Luca; De Cesare Michelandrea; Zunino Franco
E-ring-modified 7-oxyiminomethyl camptothecins: Synthesis and preliminary in vitro and in vivo biological evaluation.
Bioorganic & medicinal chemistry letters 2008;18(9):2910-5.
-
2008: Samorì Cristian; Guerrini Andrea; Varchi Greta; Zunino Franco; Beretta Giovanni Luca; Femoni Cristina; Bombardelli Ezio; Fontana Gabriele; Battaglia Arturo
Thiocamptothecin.
Journal of medicinal chemistry 2008;51(10):3040-4.
-
2008: Righetti Sabina Carla; Perego Paola; Carenini Nives; Zunino Franco
Cooperation between p53 and p73 in cisplatin-induced apoptosis in ovarian carcinoma cells.
Cancer letters 2008;263(1):140-4.
-
2008: Petrangolini Giovanna; Tortoreto Monica; Perego Paola; Carenini Nives; De Cesare Michelandrea; Balsari Andrea; Zunino Franco; Pratesi Graziella
Combination of metronomic gimatecan and CpG-oligodeoxynucleotides against an orthotopic pancreatic cancer xenograft.
Cancer biology & therapy 2008;7(4):596-601.
-
2008: Benedetti Valentina; Perego Paola; Luca Beretta Giovanni; Corna Elisabetta; Tinelli Stella; Righetti Sabina Carla; Leone Roberto; Apostoli Piero; Lanzi Cinzia; Zunino Franco
Modulation of survival pathways in ovarian carcinoma cell lines resistant to platinum compounds.
Molecular cancer therapeutics 2008;7(3):679-87.
-
2008: Giommarelli Chiara; Corti Alessandro; Supino Rosanna; Favini Enrica; Paolicchi Aldo; Pompella Alfonso; Zunino Franco
Cellular response to oxidative stress and ascorbic acid in melanoma cells overexpressing gamma-glutamyltransferase.
European journal of cancer (Oxford, England : 1990) 2008;44(5):750-9.
-
2008: Passarella Daniele; Belinghieri Francesca; Scarpellini Michele; Pratesi Graziella; Zunino Franco; Gia Ornella Maria; Via Lisa Dalla; Santoro Giuseppe; Danieli Bruno
Synthesis and biological evaluation of pyrroloiminoquinone derivatives.
Bioorganic & medicinal chemistry 2008;16(5):2431-8.
-
2008: Dallavalle Sabrina; Gattinoni Sonia; Mazzini Stefania; Scaglioni Leonardo; Merlini Lucio; Tinelli Stella; Beretta Giovanni L; Zunino Franco
Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(4):1484-9.
-
2008: Ferri Nicola; Beccalli Egle Maria; Contini Alessandro; Corsini Alberto; Antonino Manuela; Radice Tiziano; Pratesi Graziella; Tinelli Stella; Zunino Franco; Gelmi Maria Luisa
Antiproliferative effects on human tumor cells and rat aortic smooth muscular cells of 2,3-heteroarylmaleimides and heterofused imides.
Bioorganic & medicinal chemistry 2008;16(4):1691-701.
-
2008: Supino Rosanna; Petrangolini Giovanna; Pratesi Graziella; Tortoreto Monica; Favini Enrica; Bo Laura Dal; Casalini Patrizia; Radaelli Enrico; Croce Anna Cleta; Bottiroli Giovanni; Misiano Paola; Farina Carlo; Zunino Franco
Antimetastatic effect of a small-molecule vacuolar H+-ATPase inhibitor in in vitro and in vivo preclinical studies.
The Journal of pharmacology and experimental therapeutics 2008;324(1):15-22.
-
2007: Beretta Giovanni Luca; Zunino Franco
Relevance of extracellular and intracellular interactions of camptothecins as determinants of antitumor activity.
Biochemical pharmacology 2007;74(10):1437-44.
-
2007: Pisano C; Vesci L; Foderà R; Ferrara F F; Rossi C; De Cesare M; Zuco V; Pratesi G; Supino R; Zunino F
Antitumor activity of the combination of synthetic retinoid ST1926 and cisplatin in ovarian carcinoma models.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(9):1500-5.
-
2007: Pompella Alfonso; Corti Alessandro; Paolicchi Aldo; Giommarelli Chiara; Zunino Franco
Gamma-glutamyltransferase, redox regulation and cancer drug resistance.
Current opinion in pharmacology 2007;7(4):360-6.
-
2007: Cincinelli Raffaella; Dallavalle Sabrina; Nannei Raffaella; Merlini Lucio; Penco Sergio; Giannini Giuseppe; Pisano Claudio; Vesci Loredana; Ferrara Fabiana Fosca; Zuco Valentina; Zanchi Chiara; Zunino Franco
Synthesis and structure-activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids.
Bioorganic & medicinal chemistry 2007;15(14):4863-75.
-
2007: Rizzi Eleonora; Cassinelli Giuliana; Dallavalle Sabrina; Lanzi Cinzia; Cincinelli Raffaella; Nannei Raffaella; Cuccuru Giuditta; Zunino Franco
Synthesis and RET protein kinase inhibitory activity of 3-arylureidobenzylidene-indolin-2-ones.
Bioorganic & medicinal chemistry letters 2007;17(14):3962-8.
-
2007: Gandellini Paolo; Folini Marco; Bandiera Roberto; De Cesare Michelandrea; Binda Mara; Veronese Silvio; Daidone Maria Grazia; Zunino Franco; Zaffaroni Nadia
Down-regulation of human telomerase reverse transcriptase through specific activation of RNAi pathway quickly results in cancer cell growth impairment.
Biochemical pharmacology 2007;73(11):1703-14.
-
2007: De Cesare Michelandrea; Beretta Giovanni Luca; Tinelli Stella; Benedetti Valentina; Pratesi Graziella; Penco Sergio; Dallavalle Sabrina; Merlini Lucio; Pisano Claudio; Carminati Paolo; Zunino Franco
Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series.
Biochemical pharmacology 2007;73(5):656-64.
-
2007: Supino Rosanna; Favini Enrica; Cuccuru Giuditta; Zunino Franco; Scovassi A Ivana
Effect of paclitaxel on intracellular localization of c-Myc and P-c-Myc in prostate carcinoma cell lines.
Annals of the New York Academy of Sciences 2007;1095():175-81.
-
2006: Clericuzio Marco; Tabasso Silvia; Bianco Maria Ausilia; Pratesi Graziella; Beretta Giovanni; Tinelli Stella; Zunino Franco; Vidari Giovanni
Cucurbitane triterpenes from the fruiting bodies and cultivated mycelia of Leucopaxillus gentianeus.
Journal of natural products 2006;69(12):1796-9.
-
2006: Beretta Giovanni L; Petrangolini Giovanna; De Cesare Michelandrea; Pratesi Graziella; Perego Paola; Tinelli Stella; Tortoreto Monica; Zucchetti Massimo; Frapolli Roberta; Bello Ezia; Manzotti Carla; Fontana Gabriele; Bombardelli Ezio; Battaglia Arturo; Samorì Cristian; Zunino Franco
Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.
Cancer research 2006;66(22):10976-82.
-
2006: Franzini Maria; Corti Alessandro; Lorenzini Evelina; Paolicchi Aldo; Pompella Alfonso; De Cesare Michelandrea; Perego Paola; Gatti Laura; Leone Roberto; Apostoli Pietro; Zunino Franco
Modulation of cell growth and cisplatin sensitivity by membrane gamma-glutamyltransferase in melanoma cells.
European journal of cancer (Oxford, England : 1990) 2006;42(15):2623-30.
-
2006: Cassinelli Giuliana; Lanzi Cinzia; Petrangolini Giovanna; Tortoreto Monica; Pratesi Graziella; Cuccuru Giuditta; Laccabue Diletta; Supino Rosanna; Belluco Sara; Favini Enrica; Poletti Anna; Zunino Franco
Inhibition of c-Met and prevention of spontaneous metastatic spreading by the 2-indolinone RPI-1.
Molecular cancer therapeutics 2006;5(9):2388-97.
-
2006: Petrangolini Giovanna; Supino Rosanna; Pratesi Graziella; Dal Bo Laura; Tortoreto Monica; Croce Anna Cleta; Misiano Paola; Belfiore Pietro; Farina Carlo; Zunino Franco
Effect of a novel vacuolar-H+-ATPase inhibitor on cell and tumor response to camptothecins.
The Journal of pharmacology and experimental therapeutics 2006;318(3):939-46.
-
2006: Dallavalle Sabrina; Giannini Giuseppe; Alloatti Domenico; Casati Andrea; Marastoni Elena; Musso Loana; Merlini Lucio; Morini Gabriella; Penco Sergio; Pisano Claudio; Tinelli Stella; De Cesare Michelandrea; Beretta Giovanni Luca; Zunino Franco
Synthesis and cytotoxic activity of polyamine analogues of camptothecin.
Journal of medicinal chemistry 2006;49(17):5177-86.
-
2006: Petrangolini Giovanna; Cuccuru Giuditta; Lanzi Cinzia; Tortoreto Monica; Belluco Sara; Pratesi Graziella; Cassinelli Giuliana; Zunino Franco
Apoptotic cell death induction and angiogenesis inhibition in large established medullary thyroid carcinoma xenografts by Ret inhibitor RPI-1.
Biochemical pharmacology 2006;72(4):405-14.
-
2006: Danieli Bruno; Giardini Alessandra; Lesma Giordano; Passarella Daniele; Peretto Bruno; Sacchetti Alessandro; Silvani Alessandra; Pratesi Graziella; Zunino Franco
Thiocolchicine-podophyllotoxin conjugates: dynamic libraries based on disulfide exchange reaction.
The Journal of organic chemistry 2006;71(7):2848-53.
-
2006: Perego Paola; Ciusani Emilio; Gatti Laura; Carenini Nives; Corna Elisabetta; Zunino Franco
Sensitization to gimatecan-induced apoptosis by tumor necrosis factor-related apoptosis inducing ligand in prostate carcinoma cells.
Biochemical pharmacology 2006;71(6):791-8.
-
2006: Righetti Sabina C; Perego Paola; Carenini Nives; Corna Elisabetta; Dal Bo Laura; Cedrola Sabrina; La Porta Caterina A M; Zunino Franco
Molecular alterations of cells resistant to platinum drugs: role of PKCalpha.
Biochimica et biophysica acta 2006;1763(1):93-100.
-
2006: Pompella A; De Tata V; Paolicchi A; Zunino F
Expression of gamma-glutamyltransferase in cancer cells and its significance in drug resistance.
Biochemical pharmacology 2006;71(3):231-8.
-
2006: Beretta G L; Perego P; Zunino F
Mechanisms of cellular resistance to camptothecins.
Current medicinal chemistry 2006;13(27):3291-305.
-
2005: Rizzi Eleonora; Dallavalle Sabrina; Merlini Lucio; Beretta Giovanni Luca; Pratesi Graziella; Zunino Franco
A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin.
Bioorganic & medicinal chemistry letters 2005;15(19):4313-6.
-
2005: Cincinelli Raffaella; Dallavalle Sabrina; Nannei Raffaella; Carella Serena; De Zani Daniele; Merlini Lucio; Penco Sergio; Garattini Enrico; Giannini Giuseppe; Pisano Claudio; Vesci Loredana; Carminati Paolo; Zuco Valentina; Zanchi Chiara; Zunino Franco
Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity.
Journal of medicinal chemistry 2005;48(15):4931-46.
-
2005: Zuco Valentina; Zanchi Chiara; Lanzi Cinzia; Beretta Giovanni L; Supino Rosanna; Pisano Claudio; Barbarino Marcella; Zanier Romina; Bucci Federica; Aulicino Concetta; Carminati Paolo; Zunino Franco
Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response.
Neoplasia (New York, N.Y.) 2005;7(7):667-77.
-
2005: De Cesare Michelandrea; Perego Paola; Righetti Sabina C; Pratesi Graziella; Carenini Nives; Rivoltini Licia; Zupi Gabriella; Del Bufalo Donatella; Balsari Andrea; Zunino Franco
Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts.
European journal of cancer (Oxford, England : 1990) 2005;41(8):1213-22.
-
2005: Zanchi Chiara; Zuco Valentina; Lanzi Cinzia; Supino Rosanna; Zunino Franco
Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839.
Cancer research 2005;65(6):2364-72.
-
2005: Ulivi Paola; Zoli Wainer; Fabbri Francesco; Brigliadori Giovanni; Ricotti Luca; Tesei Anna; Rosetti Marco; De Cesare Michelandrea; Beretta Giovanni L; Corna Elisabetta; Supino Rosanna; Zunino Franco
Cellular basis of antiproliferative and antitumor activity of the novel camptothecin derivative, gimatecan, in bladder carcinoma models.
Neoplasia (New York, N.Y.) 2005;7(2):152-61.
-
2005: Oggionni M; Pilotti S; Suardi S; Ditto A; Luoni C; Mariani L; Scambia G; Fanfani F; Zunino F
p53 Gene status and response to topotecan-containing chemotherapy in advanced ovarian carcinoma.
Oncology 2005;69(2):154-8.
-
2005: Gatti Laura; Zunino Franco
Overview of tumor cell chemoresistance mechanisms.
Methods in molecular medicine 2005;111():127-48.
-
2004: Dominici S; Pieri L; Paolicchi A; De Tata V; Zunino F; Pompella A
Endogenous oxidative stress induces distinct redox forms of tumor necrosis factor receptor-1 in melanoma cells.
Annals of the New York Academy of Sciences 2004;1030():62-8.
-
2004: Dallavalle Sabrina; Merlini Lucio; Beretta Giovanni Luca; Tinelli Stella; Zunino Franco
Synthesis and cytotoxic activity of substituted luotonin A derivatives.
Bioorganic & medicinal chemistry letters 2004;14(23):5757-61.
-
2004: Pisano C; Merlini L; Penco S; Carminati P; Zunino F
Cellular and pharmacological bases of the antitumor activity of a novel adamantyl retinoid, ST1926.
Journal of chemotherapy (Florence, Italy) 2004;16 Suppl 4():74-6.
-
2004: De Cesare Michelandrea; Pratesi Graziella; Veneroni Silvia; Bergottini Raffaella; Zunino Franco
Efficacy of the novel camptothecin gimatecan against orthotopic and metastatic human tumor xenograft models.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(21):7357-64.
-
2004: Gatti L; Chen D; Beretta G L; Rustici G; Carenini N; Corna E; Colangelo D; Zunino F; Bähler J; Perego P
Global gene expression of fission yeast in response to cisplatin.
Cellular and molecular life sciences : CMLS 2004;61(17):2253-63.
-
2004: Cassinelli Giuliana; Supino Rosanna; Zuco Valentina; Lanzi Cinzia; Scovassi A Ivana; Semple Sean C; Zunino Franco
Role of c-myc protein in hormone refractory prostate carcinoma: cellular response to paclitaxel.
Biochemical pharmacology 2004;68(5):923-31.
-
2004: Cuccuru Giuditta; Lanzi Cinzia; Cassinelli Giuliana; Pratesi Graziella; Tortoreto Monica; Petrangolini Giovanna; Seregni Ettore; Martinetti Antonia; Laccabue Diletta; Zanchi Chiara; Zunino Franco
Cellular effects and antitumor activity of RET inhibitor RPI-1 on MEN2A-associated medullary thyroid carcinoma.
Journal of the National Cancer Institute 2004;96(13):1006-14.
-
2004: Pratesi Graziella; Beretta Giovanni L; Zunino Franco
Gimatecan, a novel camptothecin with a promising preclinical profile.
Anti-cancer drugs 2004;15(6):545-52.
-
2004: Beretta Giovanni Luca; Gatti Laura; Tinelli Stella; Corna Elisabetta; Colangelo Donato; Zunino Franco; Perego Paola
Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells.
Biochemical pharmacology 2004;68(2):283-91.
-
2004: Pennati Marzia; Binda Mara; De Cesare Michelandrea; Pratesi Graziella; Folini Marco; Citti Lorenzo; Daidone Maria Grazia; Zunino Franco; Zaffaroni Nadia
Ribozyme-mediated down-regulation of survivin expression sensitizes human melanoma cells to topotecan in vitro and in vivo.
Carcinogenesis 2004;25(7):1129-36.
-
2004: Dallavalle Sabrina; Merlini Lucio; Morini Gabriella; Musso Loana; Penco Sergio; Beretta Giovanni Luca; Tinelli Stella; Zunino Franco
Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin.
European journal of medicinal chemistry 2004;39(6):507-13.
-
2004: Gatti L; Beretta G L; Carenini N; Corna E; Zunino F; Perego P
Gene expression profiles in the cellular response to a multinuclear platinum complex.
Cellular and molecular life sciences : CMLS 2004;61(7-8):973-81.
-
2004: Petrangolini G; Cassinelli G; Pratesi G; Tortoreto M; Favini E; Supino R; Lanzi C; Belluco S; Zunino F
Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in a paclitaxel-resistant human ovarian tumour xenograft.
British journal of cancer 2004;90(7):1464-8.
-
2004: Zunino Franco; Pratesi Graziella
Camptothecins in clinical development.
Expert opinion on investigational drugs 2004;13(3):269-84.
-
2004: Croce Anna Cleta; Bottiroli Giovanni; Supino Rosanna; Favini Enrica; Zuco Valentina; Zunino Franco
Subcellular localization of the camptothecin analogues, topotecan and gimatecan.
Biochemical pharmacology 2004;67(6):1035-45.
-
2004: Zuco V; Zanchi C; Cassinelli G; Lanzi C; Supino R; Pisano C; Zanier R; Giordano V; Garattini E; Zunino F
Induction of apoptosis and stress response in ovarian carcinoma cell lines treated with ST1926, an atypical retinoid.
Cell death and differentiation 2004;11(3):280-9.
-
2003: Pisano Claudio; Pratesi Graziella; Laccabue Diletta; Zunino Franco; Lo Giudice Pietro; Bellucci Augusta; Pacifici Licia; Camerini Barbara; Vesci Loredana; Castorina Massimo; Cicuzza Sandra; Tredici Giovanni; Marmiroli Paola; Nicolini Gabriella; Galbiati Stefania; Calvani Menotti; Carminati Paolo; Cavaletti Guido
Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5756-67.
-
2003: Petrangolini Giovanna; Pratesi Graziella; De Cesare Michelandrea; Supino Rosanna; Pisano Claudio; Marcellini Marcella; Giordano Vincenzo; Laccabue Diletta; Lanzi Cinzia; Zunino Franco
Antiangiogenic effects of the novel camptothecin ST1481 (gimatecan) in human tumor xenografts.
Molecular cancer research : MCR 2003;1(12):863-70.
-
2003: Lanzi Cinzia; Cassinelli Giuliana; Cuccuru Giuditta; Zanchi Chiara; Laccabue Diletta; Zunino Franco
RET/PTC oncoproteins: molecular targets of new drugs.
Tumori 2003;89(5):520-2.
-
2003: Lanzi C; Cassinelli G; Cuccuru G; Zaffaroni N; Supino R; Vignati S; Zanchi C; Yamamoto M; Zunino F
Inactivation of Ret/Ptc1 oncoprotein and inhibition of papillary thyroid carcinoma cell proliferation by indolinone RPI-1.
Cellular and molecular life sciences : CMLS 2003;60(7):1449-59.
-
2003: Perego Paola; Gatti Laura; Righetti Sabina C; Beretta Giovanni L; Carenini Nives; Corna Elisabetta; Dal Bo Laura; Tinelli Stella; Colangelo Donato; Leone Roberto; Apostoli Piero; Lombardi Luciano; Beggiolin Gino; Piazzoni Laura; Zunino Franco
Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.
International journal of cancer. Journal international du cancer 2003;105(5):617-24.
-
2003: Paolicchi A; Sotiropuolou M; Perego P; Daubeuf S; Visvikis A; Lorenzini E; Franzini M; Romiti N; Chieli E; Leone R; Apostoli P; Colangelo D; Zunino F; Pompella A
gamma-Glutamyl transpeptidase catalyses the extracellular detoxification of cisplatin in a human cell line derived from the proximal convoluted tubule of the kidney.
European journal of cancer (Oxford, England : 1990) 2003;39(7):996-1003.
-
2003: Zuco Valentina; Supino Rosanna; De Cesare Michelandrea; Carenini Nives; Perego Paola; Gatti Laura; Pratesi Graziella; Pisano Claudio; Martinelli Roberta; Bucci Federica; Zanier Romina; Carminati Paolo; Zunino Franco
Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models.
Biochemical pharmacology 2003;65(8):1281-94.
-
2003: Pratesi G; Laccabue D; Lanzi C; Cassinelli G; Supino R; Zucchetti M; Frapolli R; D'Incalci M; Bombardelli E; Morazzoni P; Riva A; Zunino F
IDN 5390: an oral taxane candidate for protracted treatment schedules.
British journal of cancer 2003;88(6):965-72.
-
2003: Cincinelli Raffaella; Dallavalle Sabrina; Merlini Lucio; Penco Sergio; Pisano Claudio; Carminati Paolo; Giannini Giuseppe; Vesci Loredana; Gaetano Carlo; Illy Barbara; Zuco Valentina; Supino Rosanna; Zunino Franco
A novel atypical retinoid endowed with proapoptotic and antitumor activity.
Journal of medicinal chemistry 2003;46(6):909-12.
-
2003: Manic S; Gatti L; Carenini N; Fumagalli G; Zunino F; Perego P
Mechanisms controlling sensitivity to platinum complexes: role of p53 and DNA mismatch repair.
Current cancer drug targets 2003;3(1):21-9.
-
2002: Gatti L; Supino R; Perego P; Pavesi R; Caserini C; Carenini N; Righetti S C; Zuco V; Zunino F
Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response.
Cell death and differentiation 2002;9(12):1352-9.
-
2002: Pratesi Graziella; De Cesare Michelandrea; Carenini Nives; Perego Paola; Righetti Sabina C; Cucco Carla; Merlini Lucio; Pisano Claudio; Penco Sergio; Carminati Paolo; Vesci Loredana; Zunino Franco
Pattern of antitumor activity of a novel camptothecin, ST1481, in a large panel of human tumor xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3904-9.
-
2002: Beretta Giovanni L; Righetti Sabina C; Lombardi Luciano; Zunino Franco; Perego Paola
Electron microscopy analysis of early localization of cisplatin in ovarian carcinoma cells.
Ultrastructural pathology 2002;26(5):331-4.
-
2002: Zaffaroni N; Pennati M; Colella G; Perego P; Supino R; Gatti L; Pilotti S; Zunino F; Daidone M G
Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer.
Cellular and molecular life sciences : CMLS 2002;59(8):1406-12.
-
2002: Cassinelli Giuliana; Lanzi Cinzia; Supino Rosanna; Pratesi Graziella; Zuco Valentina; Laccabue Diletta; Cuccuru Giuditta; Bombardelli Ezio; Zunino Franco
Cellular bases of the antitumor activity of the novel taxane IDN 5109 (BAY59-8862) on hormone-refractory prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(8):2647-54.
-
2002: Gelfi Cecilia; Vigano Agnese; De Palma Sara; Righetti Pier Giorgio; Righetti Sabin Carla; Corna Elisabetta; Zunino Franco
Single-strand conformation polymorphism for p53 mutation by a combination of neutral pH buffer and temperature gradient in capillary electrophoresis.
Electrophoresis 2002;23(10):1517-23.
-
2002: Ciusani Emilio; Perego Paola; Carenini Nives; Corna Elisabetta; Facchinetti Federica; Boiardi Amerigo; Salmaggi Andrea; Zunino Franco
Fas/CD95-mediated apoptosis in human glioblastoma cells: a target for sensitisation to topoisomerase I inhibitors.
Biochemical pharmacology 2002;63(5):881-7.
-
2002: Paolicchi Aldo; Lorenzini Evelina; Perego Paola; Supino Rosanna; Zunino Franco; Comporti Mario; Pompella Alfonso
Extra-cellular thiol metabolism in clones of human metastatic melanoma with different gamma-glutamyl transpeptidase expression: implications for cell response to platinum-based drugs.
International journal of cancer. Journal international du cancer 2002;97(6):740-5.
-
2001: Laccabue D; Tortoreto M; Veneroni S; Perego P; Scanziani E; Zucchetti M; Zaffaroni M; D'Incalci M; Bombardelli E; Zunino F; Pratesi G
A novel taxane active against an orthotopically growing human glioma xenograft.
Cancer 2001;92(12):3085-92.
-
2001: Supino R; Perego P; Gatti L; Caserini C; Leonetti C; Colantuono M; Zuco V; Carenini N; Zupi G; Zunino F
A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant small-cell lung cancer cell line.
European journal of cancer (Oxford, England : 1990) 2001;37(17):2247-56.
-
2001: De Cesare M; Pratesi G; Perego P; Carenini N; Tinelli S; Merlini L; Penco S; Pisano C; Bucci F; Vesci L; Pace S; Capocasa F; Carminati P; Zunino F
Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin.
Cancer research 2001;61(19):7189-95.
-
2001: Dallavalle S; Ferrari A; Biasotti B; Merlini L; Penco S; Gallo G; Marzi M; Tinti M O; Martinelli R; Pisano C; Carminati P; Carenini N; Beretta G; Perego P; De Cesare M; Pratesi G; Zunino F
Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity.
Journal of medicinal chemistry 2001;44(20):3264-74.
-
2001: Lanzi C; Cassinelli G; Cuccuru G; Supino R; Zuco V; Ferlini C; Scambia G; Zunino F
Cell cycle checkpoint efficiency and cellular response to paclitaxel in prostate cancer cells.
The Prostate 2001;48(4):254-64.
-
2001: Perego P; De Cesare M; De Isabella P; Carenini N; Beggiolin G; Pezzoni G; Palumbo M; Tartaglia L; Pratesi G; Pisano C; Carminati P; Scheffer G L; Zunino F
A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.
Cancer research 2001;61(16):6034-7.
-
2001: Del Bello B; Valentini M A; Zunino F; Comporti M; Maellaro E
Cleavage of Bcl-2 in oxidant- and cisplatin-induced apoptosis of human melanoma cells.
Oncogene 2001;20(33):4591-5.
-
2001: Bigioni M; Salvatore C; Bullo A; Bellarosa D; Iafrate E; Animati F; Capranico G; Goso C; Maggi C A; Pratesi G; Zunino F; Manzini S
A comparative study of cellular and molecular pharmacology of doxorubicin and MEN 10755, a disaccharide analogue.
Biochemical pharmacology 2001;62(1):63-70.
-
2001: Cassinelli G; Supino R; Perego P; Polizzi D; Lanzi C; Pratesi G; Zunino F
A role for loss of p53 function in sensitivity of ovarian carcinoma cells to taxanes.
International journal of cancer. Journal international du cancer 2001;92(5):738-47.
-
2001: Zunino F; Pratesi G; Perego P
Role of the sugar moiety in the pharmacological activity of anthracyclines: development of a novel series of disaccharide analogs.
Biochemical pharmacology 2001;61(8):933-8.
-
2001: Gonzalez-Paz O; Polizzi D; De Cesare M; Zunino F; Bigioni M; Maggi C A; Manzini S; Pratesi G
Tissue distribution, antitumour activity and in vivo apoptosis induction by MEN10755 in nude mice.
European journal of cancer (Oxford, England : 1990) 2001;37(3):431-7.
-
2001: Pratesi G; Perego P; Zunino F
Role of Bcl-2 and its post-transcriptional modification in response to antitumor therapy.
Biochemical pharmacology 2001;61(4):381-6.
-
2001: Dallavalle S; Ferrari A; Merlini L; Penco S; Carenini N; De Cesare M; Perego P; Pratesi G; Zunino F
Novel cytotoxic 7-iminomethyl and 7-aminomethyl derivatives of camptothecin.
Bioorganic & medicinal chemistry letters 2001;11(3):291-4.
-
2001: Perego P; Corna E; De Cesare M; Gatti L; Polizzi D; Pratesi G; Supino R; Zunino F
Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines.
Current medicinal chemistry 2001;8(1):31-7.
-
2001: Sissi C; Moro S; Richter S; Gatto B; Menta E; Spinelli S; Krapcho A P; Zunino F; Palumbo M
DNA-interactive anticancer aza-anthrapyrazoles: biophysical and biochemical studies relevant to the mechanism of action.
Molecular pharmacology 2001;59(1):96-103.
-
2001: Supino R; Polizzi D; Pavesi R; Pratesi G; Guano F; Capranico G; Palumbo M; Sissi C; Richter S; Beggiolin G; Menta E; Pezzoni G; Spinelli S; Torriani D; Carenini N; Dal Bo L; Facchinetti F; Tortoreto M; Zunino F
A novel 9-aza-anthrapyrazole effective against human prostatic carcinoma xenografts.
Oncology 2001;61(3):234-42.
-
2000: Lavarino C; Pilotti S; Oggionni M; Gatti L; Perego P; Bresciani G; Pierotti M A; Scambia G; Ferrandina G; Fagotti A; Mangioni C; Lucchini V; Vecchione F; Bolis G; Scarfone G; Zunino F
p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(23):3936-45.
-
2000: Dallavalle S; Delsoldato T; Ferrari A; Merlini L; Penco S; Carenini N; Perego P; De Cesare M; Pratesi G; Zunino F
Novel 7-substituted camptothecins with potent antitumor activity.
Journal of medicinal chemistry 2000;43(21):3963-9.
-
2000: De Cesare M; Zunino F; Pace S; Pisano C; Pratesi G
Efficacy and toxicity profile of oral topotecan in a panel of human tumour xenografts.
European journal of cancer (Oxford, England : 1990) 2000;36(12):1558-64.
-
2000: Perego P; Gatti L; Carenini N; Dal Bo L; Zunino F
Apoptosis induced by extracellular glutathione is mediated by H(2)O(2) production and DNA damage.
International journal of cancer. Journal international du cancer 2000;87(3):343-8.
-
2000: Maellaro E; Dominici S; Del Bello B; Valentini M A; Pieri L; Perego P; Supino R; Zunino F; Lorenzini E; Paolicchi A; Comporti M; Pompella A
Membrane gamma-glutamyl transpeptidase activity of melanoma cells: effects on cellular H(2)O(2) production, cell surface protein thiol oxidation and NF-kappa B activation status.
Journal of cell science 2000;113 ( Pt 15)():2671-8.
-
2000: Manzotti C; Pratesi G; Menta E; Di Domenico R; Cavalletti E; Fiebig H H; Kelland L R; Farrell N; Polizzi D; Supino R; Pezzoni G; Zunino F
BBR 3464: a novel triplatinum complex, exhibiting a preclinical profile of antitumor efficacy different from cisplatin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2626-34.
-
2000: Pratesi G; Polizzi D; Perego P; Dal Bo L; Zunino F
Bcl-2 phosphorylation in a human breast carcinoma xenograft: a common event in response to effective DNA-damaging drugs.
Biochemical pharmacology 2000;60(1):77-82.
-
2000: Mancuso T; Mezzelani A; Riva C; Fabbri A; Dal Bo L; Sampietro G; Perego P; Casali P; Zunino F; Sozzi G; Pierotti M A; Pilotti S
Analysis of SYT-SSX fusion transcripts and bcl-2 expression and phosphorylation status in synovial sarcoma.
Laboratory investigation; a journal of technical methods and pathology 2000;80(6):805-13.
-
2000: Cassinelli G; Lanzi C; Pensa T; Gambetta R A; Nasini G; Cuccuru G; Cassinis M; Pratesi G; Polizzi D; Tortoreto M; Zunino F
Clavilactones, a novel class of tyrosine kinase inhibitors of fungal origin.
Biochemical pharmacology 2000;59(12):1539-47.
-
2000: Polizzi D; Pratesi G; Monestiroli S; Tortoreto M; Zunino F; Bombardelli E; Riva A; Morazzoni P; Colombo T; D'Incalci M; Zucchetti M
Oral efficacy and bioavailability of a novel taxane.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):2070-4.
-
2000: Villa R; Folini M; Perego P; Supino R; Setti E; Daidone M G; Zunino F; Zaffaroni N
Telomerase activity and telomere length in human ovarian cancer and melanoma cell lines: correlation with sensitivity to DNA damaging agents.
International journal of oncology 2000;16(5):995-1002.
-
2000: Gelfi C; Viganó A; Curcio M; Righetti P G; Righetti S C; Corna E; Zunino F
Single-strand conformation polymorphism analysis by capillary zone electrophoresis in neutral pH buffer.
Electrophoresis 2000;21(4):785-91.
-
2000: Lanzi C; Cassinelli G; Pensa T; Cassinis M; Gambetta R A; Borrello M G; Menta E; Pierotti M A; Zunino F
Inhibition of transforming activity of the ret/ptc1 oncoprotein by a 2-indolinone derivative.
International journal of cancer. Journal international du cancer 2000;85(3):384-90.
-
2000: Pratesi G; De Cesare M; Zunino F
Improvement of therapeutic index of low-dose topotecan delivered per os.
Annals of the New York Academy of Sciences 2000;922():330-3.
-
1999: Perego P; Gatti L; Caserini C; Supino R; Colangelo D; Leone R; Spinelli S; Farrell N; Zunino F
The cellular basis of the efficacy of the trinuclear platinum complex BBR 3464 against cisplatin-resistant cells.
Journal of inorganic biochemistry 1999;77(1-2):59-64.
-
1999: Pratesi G; Perego P; Polizzi D; Righetti S C; Supino R; Caserini C; Manzotti C; Giuliani F C; Pezzoni G; Tognella S; Spinelli S; Farrell N; Zunino F
A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts.
British journal of cancer 1999;80(12):1912-9.
-
1999: Righetti S C; Perego P; Corna E; Pierotti M A; Zunino F
Emergence of p53 mutant cisplatin-resistant ovarian carcinoma cells following drug exposure: spontaneously mutant selection.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(7):473-8.
-
1999: Guano F; Pourquier P; Tinelli S; Binaschi M; Bigioni M; Animati F; Manzini S; Zunino F; Kohlhagen G; Pommier Y; Capranico G
Topoisomerase poisoning activity of novel disaccharide anthracyclines.
Molecular pharmacology 1999;56(1):77-84.
-
1999: Arcamone F; Animati F; Bigioni M; Capranico G; Caserini C; Cipollone A; De Cesare M; Ettorre A; Guano F; Manzini S; Monteagudo E; Pratesi G; Salvatore C; Supino R; Zunino F
Configurational requirements of the sugar moiety for the pharmacological activity of anthracycline disaccharides.
Biochemical pharmacology 1999;57(10):1133-9.
-
1999: Zunino F; Perego P
[Pharmacologic basis of the effectiveness of topotecan in the treatment of ovarian carcinoma]
Tumori 1999;85(3 Suppl 1):S31-3.
-
1999: Polizzi D; Pratesi G; Tortoreto M; Supino R; Riva A; Bombardelli E; Zunino F
A novel taxane with improved tolerability and therapeutic activity in a panel of human tumor xenografts.
Cancer research 1999;59(5):1036-40.
-
1999: Perego P; Caserini C; Gatti L; Carenini N; Romanelli S; Supino R; Colangelo D; Viano I; Leone R; Spinelli S; Pezzoni G; Manzotti C; Farrell N; Zunino F
A novel trinuclear platinum complex overcomes cisplatin resistance in an osteosarcoma cell system.
Molecular pharmacology 1999;55(3):528-34.
-
1999: Cremonesi L; Carrera P; Fumagalli A; Lucchiari S; Cardillo E; Ferrari M; Righetti S C; Zunino F; Righetti P G; Gelfi C
Validation of double gradient denaturing gradient gel electrophoresis through multigenic retrospective analysis.
Clinical chemistry 1999;45(1):35-40.
-
1999: Böhm S; Oriana S; Spatti G; Di Re F; Breasciani G; Pirovano C; Grosso I; Martini C; Caraceni A; Pilotti S; Zunino F
Dose intensification of platinum compounds with glutathione protection as induction chemotherapy for advanced ovarian carcinoma.
Oncology 1999;57(2):115-20.
-
1998: Pratesi G; De Cesare M; Caserini C; Perego P; Dal Bo L; Polizzi D; Supino R; Bigioni M; Manzini S; Iafrate E; Salvatore C; Casazza A; Arcamone F; Zunino F
Improved efficacy and enlarged spectrum of activity of a novel anthracycline disaccharide analogue of doxorubicin against human tumor xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(11):2833-9.
-
1998: Perego P; Zunino F; Carenini N; Giuliani F; Spinelli S; Howell S B
Sensitivity to cisplatin and platinum-containing compounds of Schizosaccharomyces pombe rad mutants.
Molecular pharmacology 1998;54(1):213-9.
-
1998: Capranico G; Guano F; Moro S; Zagotto G; Sissi C; Gatto B; Zunino F; Menta E; Palumbo M
Mapping drug interactions at the covalent topoisomerase II-DNA complex by bisantrene/amsacrine congeners.
The Journal of biological chemistry 1998;273(21):12732-9.
-
1998: Binaschi M; Farinosi R; Austin C A; Fisher L M; Zunino F; Capranico G
Human DNA topoisomerase IIalpha-dependent DNA cleavage and yeast cell killing by anthracycline analogues.
Cancer research 1998;58(9):1886-92.
-
1998: Lanzi C; Perego P; Supino R; Romanelli S; Pensa T; Carenini N; Viano I; Colangelo D; Leone R; Apostoli P; Cassinelli G; Gambetta R A; Zunino F
Decreased drug accumulation and increased tolerance to DNA damage in tumor cells with a low level of cisplatin resistance.
Biochemical pharmacology 1998;55(8):1247-54.
-
1998: Perego P; Romanelli S; Carenini N; Magnani I; Leone R; Bonetti A; Paolicchi A; Zunino F
Ovarian cancer cisplatin-resistant cell lines: multiple changes including collateral sensitivity to Taxol.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1998;9(4):423-30.
-
1998: Romanelli S; Perego P; Pratesi G; Carenini N; Tortoreto M; Zunino F
In vitro and in vivo interaction between cisplatin and topotecan in ovarian carcinoma systems.
Cancer chemotherapy and pharmacology 1998;41(5):385-90.
-
1998: De Cesare M; Pratesi G; Giusti A; Polizzi D; Zunino F
Stimulation of the apoptotic response as a basis for the therapeutic synergism of lonidamine and cisplatin in combination in human tumour xenografts.
British journal of cancer 1998;77(3):434-9.
-
1997: Gelfi C; Righetti S C; Zunino F; Della Torre G; Pierotti M A; Righetti P G
Detection of p53 point mutations by double-gradient, denaturing gradient gel electrophoresis.
Electrophoresis 1997;18(15):2921-7.
-
1997: Zunino F; Perego P; Pilotti S; Pratesi G; Supino R; Arcamone F
Role of apoptotic response in cellular resistance to cytotoxic agents.
Pharmacology & therapeutics 1997;76(1-3):177-85.
-
1997: Arcamone F; Animati F; Capranico G; Lombardi P; Pratesi G; Manzini S; Supino R; Zunino F
New developments in antitumor anthracyclines.
Pharmacology & therapeutics 1997;76(1-3):117-24.
-
1997: Bigioni M; Salvatore C; Palma C; Manzini S; Animati F; Lombardi P; Pratesi G; Supino R; Zunino F
Cytotoxic and antitumor activity of MEN 10710, a novel alkylating derivative of distamycin.
Anti-cancer drugs 1997;8(9):845-52.
-
1997: Capranico G; Binaschi M; Borgnetto M E; Zunino F; Palumbo M
A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons.
Trends in pharmacological sciences 1997;18(9):323-9.
-
1997: Lanzi C; Pensa T; Cassinis M; Corti C; Gambetta R A; Pratesi G; Menta E; Ardini E; Zunino F
A cell and mechanism-based approach for the selection of EGF receptor inhibitors.
Anti-cancer drug design 1997;12(6):515-24.
-
1997: Arcamone F; Animati F; Berettoni M; Bigioni M; Capranico G; Casazza A M; Caserini C; Cipollone A; De Cesare M; Franciotti M; Lombardi P; Madami A; Manzini S; Monteagudo E; Polizzi D; Pratesi G; Righetti S C; Salvatore C; Supino R; Zunino F
Doxorubicin disaccharide analogue: apoptosis-related improvement of efficacy in vivo.
Journal of the National Cancer Institute 1997;89(16):1217-23.
-
1997: Caserini C; Pratesi G; Tortoreto M; Bedogné B; Carenini N; Supino R; Perego P; Righetti S C; Zunino F
Apoptosis as a determinant of tumor sensitivity to topotecan in human ovarian tumors: preclinical in vitro/in vivo studies.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(6):955-61.
-
1997: Binaschi M; Capranico G; Dal Bo L; Zunino F
Relationship between lethal effects and topoisomerase II-mediated double-stranded DNA breaks produced by anthracyclines with different sequence specificity.
Molecular pharmacology 1997;51(6):1053-9.
-
1997: Binaschi M; Zagotto G; Palumbo M; Zunino F; Farinosi R; Capranico G
Irreversible and reversible topoisomerase II DNA cleavage stimulated by clerocidin: sequence specificity and structural drug determinants.
Cancer research 1997;57(9):1710-6.
-
1997: Perego P; Paolicchi A; Tongiani R; Pompella A; Tonarelli P; Carenini N; Romanelli S; Zunino F
The cell-specific anti-proliferative effect of reduced glutathione is mediated by gamma-glutamyl transpeptidase-dependent extracellular pro-oxidant reactions.
International journal of cancer. Journal international du cancer 1997;71(2):246-50.
-
1997: de Isabella P; Palumbo M; Sissi C; Carenini N; Capranico G; Menta E; Oliva A; Spinelli S; Krapcho A P; Giuliani F C; Zunino F
Physicochemical properties, cytotoxic activity and topoisomerase II inhibition of 2,3-diaza-anthracenediones.
Biochemical pharmacology 1997;53(2):161-9.
-
1997: Perego P; Righetti S C; Supino R; Delia D; Caserini C; Carenini N; Bedogné B; Broome E; Krajewski S; Reed J C; Zunino F
Role of apoptosis and apoptosis-related proteins in the cisplatin-resistant phenotype of human tumor cell lines.
Apoptosis : an international journal on programmed cell death 1997;2(6):540-8.
-
1997: Capranico G; Giaccone G; Zunino F; Garattini S; D'Incalci M
DNA topoisomerase II poisons and inhibitors.
Cancer chemotherapy and biological response modifiers 1997;17():114-31.
-
1996: Cornarotti M; Tinelli S; Willmore E; Zunino F; Fisher L M; Austin C A; Capranico G
Drug sensitivity and sequence specificity of human recombinant DNA topoisomerases IIalpha (p170) and IIbeta (p180).
Molecular pharmacology 1996;50(6):1463-71.
-
1996: Paolicchi A; Pompella A; Tonarelli P; Gadducci A; Genazzani A R; Zunino F; Pratesi G; Tongiani R
Gamma-glutamyltranspeptidase activity in human ovarian carcinoma.
Anticancer research 1996;16(5B):3053-8.
-
1996: Animati F; Arcamone F; Bigioni M; Capranico G; Caserini C; De Cesare M; Lombardi P; Pratesi G; Salvatore C; Supino R; Zunino F
Biochemical and pharmacological activity of novel 8-fluoroanthracyclines: influence of stereochemistry and conformation.
Molecular pharmacology 1996;50(3):603-9.
-
1996: Cornarotti M; Capranico G; Bohm S; Oriana S; Spatti G B; Mariani L; Ballabio G; Zunino F
Gene expression of DNA topoisomerases I, II alpha and II beta and response to cisplatin-based chemotherapy in advanced ovarian carcinoma.
International journal of cancer. Journal international du cancer 1996;67(4):479-84.
-
1996: Supino R; Caserini C; Orlandi L; Zaffaroni N; Silvestrini R; Vaglini M; Zunino F
Modulation of melphalan cytotoxic activity in human melanoma cell lines.
Anti-cancer drugs 1996;7(5):604-12.
-
1996: Marchesini R; Colombo A; Caserini C; Perego P; Supino R; Capranico G; Tronconi M; Zunino F
Interaction of ionizing radiation with topotecan in two human tumor cell lines.
International journal of cancer. Journal international du cancer 1996;66(3):342-6.
-
1996: Borgnetto M E; Zunino F; Tinelli S; Kas E; Capranico G
Drug-specific sites of topoisomerase II DNA cleavage in Drosophila chromatin: heterogeneous localization and reversibility.
Cancer research 1996;56(8):1855-62.
-
1996: Righetti S C; Della Torre G; Pilotti S; Ménard S; Ottone F; Colnaghi M I; Pierotti M A; Lavarino C; Cornarotti M; Oriana S; Böhm S; Bresciani G L; Spatti G; Zunino F
A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma.
Cancer research 1996;56(4):689-93.
-
1996: Supino R; Crosti M; Clerici M; Warlters A; Cleris L; Zunino F; Formelli F
Induction of apoptosis by fenretinide (4HPR) in human ovarian carcinoma cells and its association with retinoic acid receptor expression.
International journal of cancer. Journal international du cancer 1996;65(4):491-7.
-
1996: Perego P; Giarola M; Righetti S C; Supino R; Caserini C; Delia D; Pierotti M A; Miyashita T; Reed J C; Zunino F
Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems.
Cancer research 1996;56(3):556-62.
-
1996: Bigioni M; Zunino F; Tinelli S; Austin C A; Willmore E; Capranico G
Position-specific effects of base mismatch on mammalian topoisomerase II DNA cleaving activity.
Biochemistry 1996;35(1):153-9.
-
1996: Capranico G; Giaccone G; Zunino F; Garattini S; D'Incalci M
DNA topoisomerase inhibitors.
Cancer chemotherapy and biological response modifiers 1996;16():68-87.
-
1996: Pratesi G; De Cesare M; Zunino F
Efficacy of lonidamine combined with different DNA-damaging agents in the treatment of the MX-1 tumor xenograft.
Cancer chemotherapy and pharmacology 1996;38(2):123-8.
-
1996: Corti C; Pratesi G; DeCesare M; Pellegrini R; Giardini R; Supino R; Zunino F
Spontaneous lung metastases in a human lung tumor xenograft: a new experimental model.
Journal of cancer research and clinical oncology 1996;122(3):154-60.
-
1995: Binaschi M; Supino R; Gambetta R A; Giaccone G; Prosperi E; Capranico G; Cataldo I; Zunino F
MRP gene overexpression in a human doxorubicin-resistant SCLC cell line: alterations in cellular pharmacokinetics and in pattern of cross-resistance.
International journal of cancer. Journal international du cancer 1995;62(1):84-9.
-
1995: Binaschi M; Zunino F; Capranico G
Mechanism of action of DNA topoisomerase inhibitors.
Stem cells (Dayton, Ohio) 1995;13(4):369-79.
-
1995: Pratesi G; Tortoreto M; Corti C; Giardini R; Zunino F
Successful local regional therapy with topotecan of intraperitoneally growing human ovarian carcinoma xenografts.
British journal of cancer 1995;71(3):525-8.
-
1995: Fos E; Suesa N; Borras L; Lobato C; Banfi P; Gambetta R A; Zunino F; Mauleón D; Carganico G
Synthesis of alkyl chain-modified ether lipids and evaluation of their in vitro cytotoxicity.
Journal of medicinal chemistry 1995;38(7):1216-28.
-
1995: Pratesi G; Dal Bo L; Paolicchi A; Tonarelli P; Tongiani R; Zunino F
The role of the glutathione-dependent system in tumor sensitivity to cisplatin: a study of human tumor xenografts.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1995;6(3):283-9.
-
1995: De Isabella P; Zunino F; Capranico G
Base sequence determinants of amonafide stimulation of topoisomerase II DNA cleavage.
Nucleic acids research 1995;23(2):223-9.
-
1994: Perego P; Capranico G; Supino R; Zunino F
Topoisomerase I gene expression and cell sensitivity to camptothecin in human cell lines of different tumor types.
Anti-cancer drugs 1994;5(6):645-9.
-
1994: Capranico G; Palumbo M; Tinelli S; Zunino F
Unique sequence specificity of topoisomerase II DNA cleavage stimulation and DNA binding mode of streptonigrin.
The Journal of biological chemistry 1994;269(40):25004-9.
-
1994: Palumbo M; Mabilia M; Pozzan A; Capranico G; Tinelli S; Zunino F
Conformational properties of topoisomerase II inhibitors and sequence specificity of DNA cleavage.
Journal of molecular recognition : JMR 1994;7(3):227-31.
-
1994: Bigioni M; Zunino F; Capranico G
Base mutation analysis of topoisomerase II-idarubicin-DNA ternary complex formation. Evidence for enzyme subunit cooperativity in DNA cleavage.
Nucleic acids research 1994;22(12):2274-81.
-
1994: Capranico G; Supino R; Binaschi M; Capolongo L; Grandi M; Suarato A; Zunino F
Influence of structural modifications at the 3' and 4' positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance.
Molecular pharmacology 1994;45(5):908-15.
-
1994: Mapelli E; Banfi P; Sala E; Sensi M; Supino R; Zunino F; Gambetta R A
Effect of protein kinase C inhibitors on invasiveness of human melanoma clones expressing different levels of protein kinase C isoenzymes.
International journal of cancer. Journal international du cancer 1994;57(2):281-6.
-
1994: De Cesare M; Pratesi G; De Braud F; Zunino F; Stampino C G
Remarkable antitumor activity of 5'-deoxy-5-fluorouridine in human colorectal tumor xenografts.
Anticancer research 1994;14(2A):549-54.
-
1994: Capranico G; Palumbo M; Tinelli S; Mabilia M; Pozzan A; Zunino F
Conformational drug determinants of the sequence specificity of drug-stimulated topoisomerase II DNA cleavage.
Journal of molecular biology 1994;235(4):1218-30.
-
1994: Di Leo A; Bajetta E; Biganzoli L; Bohm S; Lupi G; Oriana S; Riboldi G; Spatti G; Zunino F; Di Re F
Mitoxantrone and ifosfamide as second-line therapy of epithelial ovarian cancer. A pilot study by the I.T.M.O. Group.
European journal of cancer (Oxford, England : 1990) 1994;30A(14):2188.
-
1994: Capranico G; Giaccone G; Zunino F; Garattini S; D'Incalci M
DNA topoisomerase inhibitors.
Cancer chemotherapy and biological response modifiers 1994;15():67-86.
-
1993: Perego P; Casati G; Gambetta R A; Soranzo C; Zunino F
Effect of modulation of protein kinase C activity on cisplatin cytotoxicity in cisplatin-resistant and cisplatin-sensitive human osteosarcoma cells.
Cancer letters 1993;72(1-2):53-8.
-
1993: De Isabella P; Capranico G; Palumbo M; Sissi C; Krapcho A P; Zunino F
Sequence selectivity of topoisomerase II DNA cleavage stimulated by mitoxantrone derivatives: relationships to drug DNA binding and cellular effects.
Molecular pharmacology 1993;43(5):715-21.
-
1993: Supino R; Binaschi M; Capranico G; Gambetta R A; Prosperi E; Sala E; Zunino F
A study of cross-resistance pattern and expression of molecular markers of multidrug resistance in a human small-cell lung-cancer cell line selected with doxorubicin.
International journal of cancer. Journal international du cancer 1993;54(2):309-14.
-
1993: Capranico G; De Isabella P; Tinelli S; Bigioni M; Zunino F
Similar sequence specificity of mitoxantrone and VM-26 stimulation of in vitro DNA cleavage by mammalian DNA topoisomerase II.
Biochemistry 1993;32(12):3038-46.
-
1993: Di Re F; Bohm S; Oriana S; Spatti G B; Pirovano C; Tedeschi M; Zunino F
High-dose cisplatin and cyclophosphamide with glutathione in the treatment of advanced ovarian cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1993;4(1):55-61.
-
1993: Capranico G; Tinelli S; Zunino F; Kohn K W; Pommier Y
Effects of base mutations on topoisomerase II DNA cleavage stimulated by mAMSA in short DNA oligomers.
Biochemistry 1993;32(1):145-52.
-
1992: Lanzi C; Borrello M G; Bongarzone I; Migliazza A; Fusco A; Grieco M; Santoro M; Gambetta R A; Zunino F; Della Porta G
Identification of the product of two oncogenic rearranged forms of the RET proto-oncogene in papillary thyroid carcinomas.
Oncogene 1992;7(11):2189-94.
-
1992: Binaschi M; Giaccone G; Gazdar A F; De Isabella P; Ricotti G C; Capranico G; Zunino F
Characterization of a topoisomerase II gene rearrangement in a human small-cell lung cancer cell line.
Journal of the National Cancer Institute 1992;84(22):1710-6.
-
1992: Zunino F; Capranico G; Pratesi G; Spinelli S
Current approaches to new drug development in cancer chemotherapy.
Farmaco (Società chimica italiana : 1989) 1992;47(9):1115-32.
-
1992: Capranico G; Tinelli S; Austin C A; Fisher M L; Zunino F
Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development.
Biochimica et biophysica acta 1992;1132(1):43-8.
-
1992: Pirovano C; Balzarini A; Böhm S; Oriana S; Spatti G B; Zunino F
Peripheral neurotoxicity following high-dose cisplatin with glutathione: clinical and neurophysiological assessment.
Tumori 1992;78(4):253-7.
-
1992: Fontanelli R; Spatti G; Raspagliesi F; Zunino F; Di Re F
A preoperative single course of high-dose cisplatin and bleomycin with glutathione protection in bulky stage IB/II carcinoma of the cervix.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1992;3(2):117-21.
-
1992: Capranico G; Zunino F
DNA topoisomerase-trapping antitumour drugs.
European journal of cancer (Oxford, England : 1990) 1992;28A(12):2055-60.
-
1991: Tedeschi M; De Cesare A; Oriana S; Perego P; Silva A; Venturino P; Zunino F
The role of glutathione in combination with cisplatin in the treatment of ovarian cancer.
Cancer treatment reviews 1991;18(4):253-9.
-
1991: Bohm S; Battista Spatti G; Di Re F; Oriana S; Pilotti S; Tedeschi M; Tognella S; Zunino F
A feasibility study of cisplatin administration with low-volume hydration and glutathione protection in the treatment of ovarian carcinoma.
Anticancer research 1991;11(4):1613-6.
-
1991: Guazzoni L; Perego P; Banfi P; Zunino F
Modulation of epidermal growth factor receptor tyrosine phosphorylation by tumor necrosis factor.
Cancer letters 1991;57(2):103-8.
-
1991: Pratesi G; Manzotti C; Tortoreto M; Audisio R A; Zunino F
Differential efficacy of flavone acetic against liver versus lung metastases in a human tumour xenograft.
British journal of cancer 1991;63(1):71-4.
-
1991: Lanzi C; Gambetta R A; Perego P; Banfi P; Franzi A; Guazzoni L; Zunino F
Protein kinase C activation by anthracyclines in Swiss 3T3 cells.
International journal of cancer. Journal international du cancer 1991;47(1):136-42.
-
1991: Villani F; Galimberti M; Zunino F; Monti E; Rozza A; Lanza E; Favalli L; Poggi P
Prevention of doxorubicin-induced cardiomyopathy by reduced glutathione.
Cancer chemotherapy and pharmacology 1991;28(5):365-9.
-
1991: De Isabella P; Capranico G; Zunino F
The role of topoisomerase II in drug resistance.
Life sciences 1991;48(23):2195-205.
-
1990: Cozzaglio L; Doci R; Colella G; Zunino F; Casciarri G; Gennari L;
A feasibility study of high-dose cisplatin and 5-fluorouracil with glutathione protection in the treatment of advanced colorectal cancer.
Tumori 1990;76(6):590-4.
-
1990: Soranzo C; Perego P; Zunino F
Effect of tumor necrosis factor on human tumor cell lines sensitive and resistant to cytotoxic drugs, and its interaction with chemotherapeutic agents.
Anti-cancer drugs 1990;1(2):157-63.
-
1990: Zunino F; Pratesi G; Formelli F; Pasini A
Evaluation of a platinum-doxorubicin complex in experimental tumor systems.
Investigational new drugs 1990;8(4):341-5.
-
1990: Zunino F; Capranico G
DNA topoisomerase II as the primary target of anti-tumor anthracyclines.
Anti-cancer drug design 1990;5(4):307-17.
-
1990: Soranzo C; Pratesi G; Zunino F
Different interaction of cisplatin and etoposide on in vivo and in vitro tumor systems.
Anti-cancer drugs 1990;1(1):23-8.
-
1990: Pratesi G; Capranico G; Binaschi M; De Isabella P; Pilotti S; Supino R; Zunino F
Relationships among tumor responsiveness, cell sensitivity, doxorubicin cellular pharmacokinetics and drug-induced DNA alterations in two human small-cell lung cancer xenografts.
International journal of cancer. Journal international du cancer 1990;46(4):669-74.
-
1990: Tedeschi M; Bohm S; Di Re F; Oriana S; Spatti G B; Tognella S; Zunino F
Glutathione and detoxification.
Cancer treatment reviews 1990;17(2-3):203-8.
-
1990: Binaschi M; Capranico G; De Isabella P; Mariani M; Supino R; Tinelli S; Zunino F
Comparison of DNA cleavage induced by etoposide and doxorubicin in two human small-cell lung cancer lines with different sensitivities to topoisomerase II inhibitors.
International journal of cancer. Journal international du cancer 1990;45(2):347-52.
-
1990: De Isabella P; Capranico G; Binaschi M; Tinelli S; Zunino F
Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells.
Molecular pharmacology 1990;37(1):11-6.
-
1990: Di Re F; Bohm S; Oriana S; Spatti G B; Zunino F
Efficacy and safety of high-dose cisplatin and cyclophosphamide with glutathione protection in the treatment of bulky advanced epithelial ovarian cancer.
Cancer chemotherapy and pharmacology 1990;25(5):355-60.
-
1990: Villani F; Manzotti C; Mella M; Monti E; Savi G; Zunino F
Effect of amrinone on anthracycline-induced lethal and cardiac toxicity in mice and rats.
Medical oncology and tumor pharmacotherapy 1990;7(4):227-32.
-
1990: Villani F; Galimberti M; Monti E; Piccinini F; Lanza E; Rozza A; Favalli L; Poggi P; Zunino F
Effect of glutathione and N-acetylcysteine on in vitro and in vivo cardiac toxicity of doxorubicin.
Free radical research communications 1990;11(1-3):145-51.
-
1989: Soranzo C; Ingrosso A; Buffa M; Della Torre G; Gambetta R A; Zunino F
Changes in the three-dimensional organization of LoVo cells associated with resistance to doxorubicin.
Cancer letters 1989;48(1):37-41.
-
1989: Gambetta R A; Banfi P; Lanzi C; Franzi A; Zunino F
Protein kinase C activation and lipid peroxidation by doxorubicin analogues.
Tumori 1989;75(4):358-61.
-
1989: Capranico G; De Isabella P; Castelli C; Supino R; Parmiani G; Zunino F
P-glycoprotein gene amplification and expression in multidrug-resistant murine P388 and B16 cell lines.
British journal of cancer 1989;59(5):682-5.
-
1989: Capranico G; De Isabella P; Penco S; Tinelli S; Zunino F
Role of DNA breakage in cytotoxicity of doxorubicin, 9-deoxydoxorubicin, and 4-demethyl-6-deoxydoxorubicin in murine leukemia P388 cells.
Cancer research 1989;49(8):2022-7.
-
1989: Soranzo C; Ingrosso A; Pratesi G; Lombardi L; Pilotti S; Zunino F
Malignant transformation of host cells by a human small cell lung cancer xenografted into nude mice.
Anticancer research 1989;9(2):361-6.
-
1989: Pratesi G; Manzotti C; Tortoreto M; Prosperi E; Zunino F
Effects of 5-FU and cis-DDP combination on human colorectal tumor xenografts.
Tumori 1989;75(1):60-5.
-
1989: Zunino F; Pratesi G; Micheloni A; Cavalletti E; Sala F; Tofanetti O
Protective effect of reduced glutathione against cisplatin-induced renal and systemic toxicity and its influence on the therapeutic activity of the antitumor drug.
Chemico-biological interactions 1989;70(1-2):89-101.
-
1989: Capranico G; Tinelli S; Zunino F
Formation, resealing and persistence of DNA breaks produced by 4-demethoxydaunorubicin in P388 leukemia cells.
Chemico-biological interactions 1989;72(1-2):113-23.
-
1988: Melloni E; Dasdia T; Fava G; Rocca E; Zunino F; Marchesini R
In vitro photosensitizing properties of rhodamine 123 on different human tumor cell lines.
Photochemistry and photobiology 1988;48(3):311-4.
-
1988: Pratesi G; Gianni L; Manzotti C; Zunino F
Sequence dependence of the antitumor and toxic effects of 5-fluorouracil and cis-diamminedichloroplatinum combination on primary colon tumors in mice.
Cancer chemotherapy and pharmacology 1988;21(3):237-40.
-
1987: Supino R; Gibelli N; Nano R; Pezzoni G; Zunino F
In vitro and in vivo studies of poly-L-lysine as inducer of Friend leukemic cells differentiation.
Tumori 1987;73(5):431-6.
-
1987: Oriana S; Böhm S; Spatti G; Zunino F; Di Re F
A preliminary clinical experience with reduced glutathione as protector against cisplatin-toxicity.
Tumori 1987;73(4):337-40.
-
1987: Capranico G; Riva A; Tinelli S; Dasdia T; Zunino F
Markedly reduced levels of anthracycline-induced DNA strand breaks in resistant P388 leukemia cells and isolated nuclei.
Cancer research 1987;47(14):3752-6.
-
1987: Zunino F; Pratesi G; Pezzoni G
Increased therapeutic efficacy and reduced toxicity of doxorubicin linked to pyran copolymer via the side chain of the drug.
Cancer treatment reports 1987;71(4):367-73.
-
1987: Marchesini R; Melloni E; Bottiroli G; Andreola S; Fava G; Mella M; Savi G; Zunino F
Topical administration of tetrasodium-meso-tetraphenyl-porphinesulfonate (TPPS): correlation between drug penetration and depth of necrosis in skin of nude mice following red light irradiation.
Tumori 1987;73(1):11-7.
-
1986: Capranico G; Soranzo C; Zunino F
Single-strand DNA breaks induced by chromophore-modified anthracyclines in P388 leukemia cells.
Cancer research 1986;46(11):5499-503.
-
1986: Cavalletti E; Tofanetti O; Zunino F
Comparison of reduced glutathione with 2-mercaptoethane sulfonate to prevent cyclophosphamide-induced urotoxicity.
Cancer letters 1986;32(1):1-6.
-
1986: Capranico G; Babudri N; Casciarri G; Dolzani L; Gambetta R A; Longoni E; Pani B; Soranzo C; Zunino F
Lack of effect of glutathione depletion on cytotoxicity, mutagenicity and DNA damage produced by doxorubicin in cultured cells.
Chemico-biological interactions 1986;57(2):189-201.
-
1986: Zunino F; Barbieri B; Bellini O; Casazza A M; Geroni C; Giuliani F; Ciana A; Manzini G; Quadrifoglio F
Biochemical and biological activity of the anthracycline analog, 4-demethyl-6-O-methyl-doxorubicin.
Investigational new drugs 1986;4(1):17-23.
-
1986: Marchesini R; Melloni E; Pezzoni G; Savi G; Zunino F; Docchio F; Fava G
A study on the possible involvement of nonlinear mechanism of light absorption by HpD with Nd:YAG laser.
Lasers in surgery and medicine 1986;6(3):323-7.
-
1985: Pratesi G; Savi G; Pezzoni G; Bellini O; Penco S; Tinelli S; Zunino F
Poly-L-aspartic acid as a carrier for doxorubicin: a comparative in vivo study of free and polymer-bound drug.
British journal of cancer 1985;52(6):841-8.
-
1985: Tofanetti O; Cavalletti E; Besati A; Pratesi G; Pezzoni G; Zunino F
Prevention of cyclophosphamide-induced urotoxicity by reduced glutathione and its effect on acute toxicity and antitumor activity of the alkylating agent.
Cancer chemotherapy and pharmacology 1985;14(3):188-93.
-
1984: Pezzoni G; Savi G; Melloni E; Marchesini R; Fava G; Locati L; Zunino F
A comparison of efficacy of photoradiation therapy and other conventional treatment modalities on experimental MS-2 sarcoma.
Cancer letters 1984;25(2):209-16.
-
1984: Bandieramonte G; Marchesini R; Melloni E; Andreoli C; di Pietro S; Spinelli P; Fava G; Zunino F; Emanuelli H
Laser phototherapy following HpD administration in superficial neoplastic lesions.
Tumori 1984;70(4):327-34.
-
1984: Melloni E; Marchesini R; Emanuelli H; Fava G; Locati L; Pezzoni G; Savi G; Zunino F
Hyperthermal effects in phototherapy with hematoporphyrin derivative sensitization.
Tumori 1984;70(4):321-5.
-
1984: Babudri N; Pani B; Tamaro M; Monti-Bragadin C; Zunino F
Mutagenic and cytotoxic activity of doxorubicin and daunorubicin derivatives on prokaryotic and eukaryotic cells.
British journal of cancer 1984;50(1):91-6.
-
1984: Zunino F; Savi G; Giuliani F; Gambetta R; Supino R; Tinelli S; Pezzoni G
Comparison of antitumor effects of daunorubicin covalently linked to poly-L-amino acid carriers.
European journal of cancer & clinical oncology 1984;20(3):421-5.
-
1983: Gambetta R A; Colombo A; Lanzi C; Zunino F
Purification and partial characterization of a daunorubicin-binding protein from rat liver.
Molecular pharmacology 1983;24(2):336-40.
-
1983: Zunino F; Marchesini R; Melloni E; Savi G; Pezzoni G; Locati L; Fava G
Effectiveness of laser photoradiation therapy following hematoporphyrin derivative administration in the experimental MS-2 tumor model.
Tumori 1983;69(4):305-8.
-
1983: Zunino F; Tofanetti O; Besati A; Cavalletti E; Savi G
Protective effect of reduced glutathione against cis-dichlorodiammine platinum (II)-induced nephrotoxicity and lethal toxicity.
Tumori 1983;69(2):105-11.
-
1983: Emanuelli H; Bandieramonte G; Marchesini R; Fava G; Rodari A; Colombo M P; Costa A; Spinelli P; Zunino F; Chiesa F; Cascinelli N; Andreola S; Pariente R; Canti G F
Laser oncology in Italy: experimental research and clinical applications at the National Cancer Institute, Milan.
Lasers in surgery and medicine 1983;2(4):373-81.
-
1983: Bargiotti A; Casazza A M; Cassinelli G; Di Marco A; Penco S; Pratesi G; Supino R; Zaccara A; Zunino F; Arcamone F
Synthesis, biological and biochemical properties of new anthracyclines modified in the aminosugar moiety.
Cancer chemotherapy and pharmacology 1983;10(2):84-9.
-
1982: Bossa R; Galatulas I; Savi G; Supino R; Zunino F
Reduction of lethal toxicity of doxorubicin by amrinone.
Tumori 1982;68(6):499-504.
-
1982: Zunino F; Giuliani F; Savi G; Dasdia T; Gambetta R
Anti-tumor activity of daunorubicin linked to poly-L-aspartic acid.
International journal of cancer. Journal international du cancer 1982;30(4):465-70.
-
1981: Zunino F; Gambetta R; Vigevani A; Penco S; Geroni C; Di Marco A
Biologic activity of daunorubicin linked to proteins via the methylketone side chain.
Tumori 1981;67(6):521-4.
-
1981: Zunino F; Gambetta R A; Zaccara A; Carsana R
A differential interaction of doxorubicin and daunorubicin with human serum proteins.
Tumori 1981;67(5):399-403.
-
1981: Zunino F; Casazza A M; Pratesi G; Formelli F; DiMarco A
Effect of the methylation of aglycone hydroxyl groups on the biological and biochemical properties of daunorubicin.
Biochemical pharmacology 1981;30(13):1856-8.
-
1980: Zunino F; Di Marco A; Zaccara A; Gambetta R A
The interaction of daunorubicin and doxorubicin with DNA and chromatin.
Biochimica et biophysica acta 1980;607(2):206-14.
Sign-in to see more
