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Patrick Brown

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Monica A Valentovic; Napoleon Alejandro; A Betts Carpenter; Patrick I Brown; Kenneth Ramos
Streptozotocin (STZ) diabetes enhances benzo(alpha)pyrene induced renal injury in Sprague Dawley rats.
Gary O Rankin; Suk K Hong; Dianne K Anestis; Travis T Henderson; John G Ball; Monica A Valentovic; Patrick I Brown
Effect of three n-acetylamino acids on N-(3,5-dichlorophenyl)succinimide (NDPS) and ndps metabolite nephrotoxicity in Fischer 344 rats.
Gary O Rankin; H Sun; Dianne K Anestis; O Noe; John G Ball; Monica A Valentovic; Patrick I Brown; J L Hubbard
Role of stereochemistry in N-(3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2-NDHSA) nephrotoxicity.

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2006: Monica A Valentovic; Napoleon Alejandro; A Betts Carpenter; Patrick I Brown; Kenneth Ramos
Streptozotocin (STZ) diabetes enhances benzo(alpha)pyrene induced renal injury in Sprague Dawley rats.
Toxicology letters 2006;164(3):214-20.
2002: Gary O Rankin; Suk K Hong; Dianne K Anestis; Travis T Henderson; John G Ball; Monica A Valentovic; Patrick I Brown
Effect of three n-acetylamino acids on N-(3,5-dichlorophenyl)succinimide (NDPS) and ndps metabolite nephrotoxicity in Fischer 344 rats.
Journal of toxicology and environmental health. Part A 2002;65(7):539-56.
2001: Gary O Rankin; H Sun; Dianne K Anestis; O Noe; John G Ball; Monica A Valentovic; Patrick I Brown; J L Hubbard
Role of stereochemistry in N-(3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2-NDHSA) nephrotoxicity.
Toxicology 2001;168(3):241-50.
2001: Suk K Hong; Dianne K Anestis; Monica A Valentovic; John G Ball; Patrick I Brown; Gary O Rankin
Gender differences in the potentiation of N-(3,5-dichlorophenyl)succinimide metabolite nephrotoxicity by phenobarbital.
Journal of toxicology and environmental health. Part A 2001;64(3):241-56.
1999: Suk K Hong; Dianne K Anestis; John G Ball; Monica A Valentovic; Patrick I Brown; Gary O Rankin
Sodium sulfate potentiates N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS) and N-(3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2-NDHSA) nephrotoxicity in the Fischer 344 rat.
Toxicology 1999;138(3):165-74.
1999: J L Hubbard; O Noe; M Egermayer; Suk K Hong; Dianne K Anestis; Monica A Valentovic; John G Ball; Patrick I Brown; Gary O Rankin
Nephrotoxic potential of N-(3,5-dichloro-4-fluorophenyl)succinimide in Fischer 344 rats: comparison with N-(3,4,5-trichlorophenyl)succinimide.
Toxicology 1999;132(2-3):127-37.
1999: Suk K Hong; Dianne K Anestis; C Skaggs; Patrick I Brown; Gary O Rankin
The role of glucuronidation in N-(3,5-dichlorophenyl)succinimide (NDPS) nephrotoxicity: nephrotoxic potential of NDPS and NDPS metabolites in Gunn, Wistar, and Fischer 344 rats.
Toxicology and applied pharmacology 1999;154(2):170-80.
1999: Suk K Hong; Dianne K Anestis; Patrick I Brown; Gary O Rankin
Effect of glucuronidation substrates/inhibitors on N-(3,5-dichlorophenyl)succinimide nephrotoxicity in Fischer 344 rats.
Toxicology 1999;132(1):43-55.
1998: Suk K Hong; Dianne K Anestis; Monica A Valentovic; John G Ball; Patrick I Brown; R T Wang; Gary O Rankin
Gender differences in acute N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS) and N-(3,5-dichlorophenyl)-2-hydroxysuccinamic acid (2-NDHSA) nephrotoxicity in Fischer 344 rats.
Journal of toxicology and environmental health. Part A 1998;54(8):613-32.
1997: Monica A Valentovic; T Yahia; John G Ball; Suk K Hong; Patrick I Brown; Gary O Rankin
3,4-Dicholoroaniline acute toxicity in male Fischer 344 rats.
Toxicology 1997;124(2):125-34.
1997: Gary O Rankin; Suk K Hong; Monica A Valentovic; K W Beers; Dianne K Anestis; D W Nicoll; John G Ball; Patrick I Brown
Effects of sodium sulfate on acute N-(3,5-dichlorophenyl)succinimide (NDPS) nephrotoxicity in the Fischer 344 rat.
Toxicology 1997;123(1-2):1-13.
1997: Suk K Hong; Dianne K Anestis; John G Ball; Monica A Valentovic; Patrick I Brown; Gary O Rankin
4-Amino-2,6-dichlorophenol nephrotoxicity in the Fischer 344 rat: protection by ascorbic acid, AT-125, and aminooxyacetic acid.
Toxicology and applied pharmacology 1997;147(1):115-25.
1996: Suk K Hong; Monica A Valentovic; Dianne K Anestis; John G Ball; Patrick I Brown; Gary O Rankin
Nephrotoxicity of 4-amino-2-chlorophenol and 2-amino-4-chlorophenol in the Fischer 344 rat.
Toxicology 1996;110(1-3):47-58.
1996: Suk K Hong; Dianne K Anestis; N M Hawco; Monica A Valentovic; Patrick I Brown; Gary O Rankin
Nephrotoxicity of N-(3-bromophenyl)-2-hydroxysuccinimide: role of halogen groups in the nephrotoxic potential of N-(halophenyl) succinimides.
Toxicology 1996;110(1-3):17-25.
1996: Gary O Rankin; K W Beers; D W Nicoll; Dianne K Anestis; Suk K Hong; J L Hubbard; John G Ball; Monica A Valentovic; Patrick I Brown
Nephrotoxic potential of 2-amino-5-chlorophenol and 4-amino-3-chlorophenol in Fischer 344 rats: comparisons with 2- and 4-chloroaniline and 2- and 4-aminophenol.
Toxicology 1996;108(1-2):109-23.
1995: Monica A Valentovic; H H Lo; Patrick I Brown; Gary O Rankin
3,5-Dichloroaniline toxicity in Fischer 344 rats pretreated with inhibitors and inducers of cytochrome P450.
Toxicology letters 1995;78(3):207-14.
1995: Gary O Rankin; K W Beers; D W Nicoll; Dianne K Anestis; John G Ball; Monica A Valentovic; Patrick I Brown
Effect of dimethyl sulfoxide on N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity.
Toxicology 1995;100(1-3):79-88.
1995: Gary O Rankin; H C Shih; Suk K Hong; D W Nicoll; Dianne K Anestis; John G Ball; Patrick I Brown; Monica A Valentovic
Role of chloride groups in the nephrotoxic potential of N-(3,5-dichlorophenyl)-2-hydroxysuccinimide, an oxidative metabolite of N-(3,5-dichlorophenyl)succinimide.
Toxicology letters 1995;78(1):49-56.
1995: Gary O Rankin; Monica A Valentovic; D W Nicoll; John G Ball; Dianne K Anestis; Patrick I Brown; J L Hubbard
Acute renal and hepatic effects induced by 3-haloanilines in the Fischer 344 rat.
Journal of applied toxicology : JAT 1995;15(2):139-46.
1994: H H Lo; Monica A Valentovic; Patrick I Brown; Gary O Rankin
Effect of chemical form, route of administration and vehicle on 3,5-dichloroaniline-induced nephrotoxicity in the Fischer 344 rat.
Journal of applied toxicology : JAT 1994;14(6):417-22.
1994: Gary O Rankin; Monica A Valentovic; D W Nicoll; John G Ball; Dianne K Anestis; R T Wang; Patrick I Brown
In vivo and in vitro 4-amino-2,6-dichlorophenol nephrotoxicity and hepatotoxicity in the Fischer 344 rat.
Toxicology 1994;90(1-2):115-28.
1994: Gary O Rankin; K W Beers; V J Teets; D W Nicoll; Dianne K Anestis; Patrick I Brown; R T Wang
Acute N-(3,5-dichlorophenyl)succinimide nephrotoxicity in female Fischer 344 rats.
Toxicology 1994;88(1-3):151-64.
1993: K W Beers; D W Nicoll; Dianne K Anestis; Patrick I Brown; Gary O Rankin
Effect of microsomal enzyme modulators on N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS)-induced nephrotoxicity in the Fischer 344 rat.
Toxicology 1993;84(1-3):141-55.
1993: Gary O Rankin; Monica A Valentovic; K W Beers; D W Nicoll; John G Ball; Dianne K Anestis; Patrick I Brown; J L Hubbard
Renal and hepatic toxicity of monochloroacetanilides in the Fischer 344 rat.
Toxicology 1993;79(3):181-93.
1992: Gary O Rankin; K W Beers; D W Nicoll; Dianne K Anestis; H C Shih; Patrick I Brown; J L Hubbard
Role of para-hydroxylation in phensuximide-induced urotoxicity in the Fischer 344 rat.
Toxicology 1992;74(1):77-88.
1992: Gary O Rankin; V J Teets; H Shih; K W Beers; D W Nicoll; Dianne K Anestis; Patrick I Brown; J L Hubbard
Renal effects of N-(3,5-disubstitutedphenyl)-succinimides in the Fischer 344 rat.
Journal of applied toxicology : JAT 1992;12(3):211-6.
1992: Peter J Harvison; R J Griffin; V J Teets; D W Nicoll; Patrick I Brown; Gary O Rankin
Nephrotoxic potential of N-(3,5-dichloro-4-hydroxyphenyl)succinimide and N-(3,5-dichloro-4-hydroxyphenyl)succinamic acid in Fischer-344 rats.
Toxicology letters 1992;60(2):221-6.
1991: H H Lo; Patrick I Brown; Gary O Rankin
Trichloroaniline effects on renal function in vivo and in vitro.
Toxicology letters 1991;57(3):319-28.
1991: Gary O Rankin; V J Teets; D W Nicoll; Patrick I Brown
Effect of buthionine sulfoximine on N-(3,5-dichlorophenyl)-2-hydroxysuccinimide and N-(3,5-dichlorophenyl)-2-hydroxysuccinamic acid nephrotoxicity.
Toxicology letters 1991;57(3):297-308.
1991: Gary O Rankin; V J Teets; D W Nicoll; Patrick I Brown
Interactions among nephrotoxicants: N-(3,5-dichlorophenyl)succinimide and cephaloridine.
Toxicology 1991;66(1):47-62.
1991: Gary O Rankin; Monica A Valentovic; V J Teets; D W Nicoll; C H Sutherland; Patrick I Brown
Effect of calcium antagonism by nifedipine and chlorpromazine on acute N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity in Fischer 344 rats.
Toxicology 1991;66(1):19-34.
1991: Gary O Rankin; Monica A Valentovic; V J Teets; D W Nicoll; Dianne K Anestis; Patrick I Brown
Effect of autacoid modulation on N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity.
Toxicology 1991;70(3):327-44.
1991: B S Huang; Monica A Valentovic; C A Gruetter; G O Rankin; Patrick I Brown; Gary L. Wright
Hypercholesterolemia and changes of vascular contractile responses in experimentally uremic rats.
Clinical and experimental hypertension. Part A, Theory and practice 1991;13(6-7):1249-73.
1991: Gary O Rankin; H C Shih; V J Teets; D J Yang; D W Nicoll; Patrick I Brown
N-(3,5-dichlorophenyl)succinimide nephrotoxicity: evidence against the formation of nephrotoxic glutathione or cysteine conjugates.
Toxicology 1991;68(3):307-25.
1990: Gary O Rankin; Monica A Valentovic; V J Teets; D W Nicoll; Patrick I Brown
Autacoid modulation and N-(3,5-dichlorophenyl)succinimide nephrotoxicity.
Toxicology letters 1990;53(1-2):207-9.
1990: H H Lo; Patrick I Brown; Gary O Rankin
Acute nephrotoxicity induced by isomeric dichloroanilines in Fischer 344 rats.
Toxicology 1990;63(2):215-31.
1990: Gary O Rankin; V J Teets; D W Nicoll; Patrick I Brown
Acute effects of the antiepileptic succinimides on the urinary tract and potentiation of phensuximide-induced urotoxicity by phenobarbital.
Journal of applied toxicology : JAT 1990;10(3):203-9.
1990: Gary O Rankin; V J Teets; D W Nicoll; Patrick I Brown
Effect of buthionine sulfoximine on acute N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity in Fischer 344 rats.
Toxicology letters 1990;52(1):91-100.
1990: Gary O Rankin; H C Shih; V J Teets; D W Nicoll; Patrick I Brown
Acute toxicity induced by 2-aryl-N-methylsuccinimides.
Journal of applied toxicology : JAT 1990;10(2):143-52.
1989: Gary O Rankin; H Shih; V J Teets; D W Nicoll; Patrick I Brown
Acute nephrotoxicity induced by N-(3,5-dichlorophenyl)-3-hydroxysuccinamic acid in Fischer 344 rats.
Toxicology letters 1989;48(3):217-23.
1989: Gary O Rankin; J M Carl; J L Hubbard; V J Teets; D W Nicoll; Patrick I Brown
Renal and hepatic toxicity of N-arylsuccinimides in Fischer 344 rats.
Journal of applied toxicology : JAT 1989;9(4):223-8.
1989: Gary O Rankin; V J Teets; D W Nicoll; Patrick I Brown
Comparative acute renal effects of three N-(3,5-dichlorophenyl)carboximide fungicides: N-(3,5-dichlorophenyl)succinimide, vinclozolin and iprodione.
Toxicology 1989;56(3):263-72.
1988: Gary O Rankin; H C Shih; D J Yang; C D Richmond; V J Teets; Patrick I Brown
Nephrotoxicity of N-(3,5-dichlorophenyl)succinimide metabolites in vivo and in vitro.
Toxicology and applied pharmacology 1988;96(3):405-16.
1988: Monica A Valentovic; C Elliott; V J Teets; Patrick I Brown; D Yang; Gary O Rankin
Enzyme induction produced by N-(3,5-dichlorophenyl)succinimide (NDPS) in rats.
Biochemical pharmacology 1988;37(4):768-70.
1987: H H Lo; V J Teets; D J Yang; Patrick I Brown; Gary O Rankin
Acetone effects on N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity.
Toxicology letters 1987;38(1-2):161-8.
1987: Gary O Rankin; D J Yang; C D Richmond; V J Teets; R T Wang; Patrick I Brown
Effect of microsomal enzyme activity modulation on N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity.
Toxicology 1987;45(3):269-89.
1987: D J Yang; V J Teets; B Bolton; Patrick I Brown; Gary O Rankin
Role of glutathione in acute N-(3,5-dichlorophenyl) succinimide-induced nephrotoxicity in Sprague-Dawley and Fischer 344 rats.
Toxicology 1987;45(1):25-44.
1987: D J Yang; Patrick I Brown; H H Lo; V J Teets; Gary O Rankin
Structure-nephrotoxicity relationships for meta-substituted N-phenylsuccinimides.
Journal of applied toxicology : JAT 1987;7(3):153-60.
1987: Gary O Rankin; D J Yang; V J Teets; H H Lo; Patrick I Brown
The effect of probenecid on acute N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity in the Fischer 344 rat.
Toxicology 1987;44(2):181-92.
1987: D J Yang; H H Lo; V J Teets; Patrick I Brown; Gary O Rankin
Nephrotoxicity of N-(3,5-dihalophenyl)succinimides in Fischer 344 rats.
Journal of toxicology and environmental health 1987;20(4):333-46.
1986: Gary O Rankin; D J Yang; V J Teets; Patrick I Brown
Deuterium isotope effect in acute N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity.
Life sciences 1986;39(14):1291-9.
1986: Gary O Rankin; K Cressey-Veneziano; R T Wang; Patrick I Brown
Urinary tract effects of phensuximide in the Sprague-Dawley and Fischer 344 rat.
Journal of applied toxicology : JAT 1986;6(5):349-56.
1986: D J Yang; E P Lahoda; Patrick I Brown; Gary O Rankin
Acute N-(3,4,5-trichlorophenyl)succinimide-induced nephrotoxicity in Sprague-Dawley and Fischer-344 rats.
Toxicology letters 1986;31(3):219-28.
1986: Gary O Rankin; D J Yang; K Cressey-Veneziano; S Casto; R T Wang; Patrick I Brown
In vivo and in vitro nephrotoxicity of aniline and its monochlorophenyl derivatives in the Fischer 344 rat.
Toxicology 1986;38(3):269-83.
1986: Gary O Rankin; D J Yang; V J Teets; H H Lo; Patrick I Brown
3,5-Dichloroaniline-induced nephrotoxicity in the Sprague-Dawley rat.
Toxicology letters 1986;30(2):173-9.
1985: D J Yang; E P Lahoda; Patrick I Brown; Gary O Rankin
Acute nephrotoxicity of isomeric N-(dichlorophenyl)succinimides in Sprague-Dawley and Fischer 344 rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1985;5(6 Pt 1):1119-27.
1985: D J Yang; C D Richmond; V J Teets; Patrick I Brown; Gary O Rankin
Effect of succinimide ring modification on N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity in Sprague-Dawley and Fischer 344 rats.
Toxicology 1985;37(1-2):65-77.
1985: D J Yang; E P Lahoda; Patrick I Brown; Gary O Rankin
Structure-nephrotoxicity relationships for para-substituted N-phenylsuccinimides in Sprague-Dawley and Fischer 344 rats.
Toxicology 1985;36(1):23-35.
1985: Gary O Rankin; D J Yang; E P Lahoda; K Cressey-Veneziano; M L Bailey; Patrick I Brown
Acute nephrotoxicity of N-phenyl and N-(monochlorophenyl) succinimides in Fischer 344 and Sprague-Dawley rats.
Toxicology 1985;34(4):299-308.
1985: Gary O Rankin; D J Yang; K Cressey-Veneziano; Patrick I Brown
N-(3,5-Dichlorophenyl)succinimide nephrotoxicity in the Fischer-344 rat.
Toxicology letters 1985;24(1):99-105.
1985: Gary O Rankin; D J Yang; K Cressey-Veneziano; R T Wang; Patrick I Brown
In vivo and in vitro effects of azaconazole on renal function in the Fischer 344 rat.
Toxicology 1985;34(1):1-11.
1984: Gary O Rankin; K Cressey-Veneziano; Patrick I Brown
Onset of and recovery from acute N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity in Sprague-Dawley rats.
Toxicology 1984;30(3):205-16.