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Mika Ala-Korpela

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Magnetic Resonance Spectroscopy

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Ville-Petteri Mäkinen; O T Raitakari; M Savolainen; Pasi Soininen; Lena M Thorn; N Tolonen; J Viikari; Mika Ala-Korpela; Carol Forsblom; P-H Groop; A J Kangas
Triglyceride-cholesterol imbalance across lipoprotein subclasses predicts diabetic kidney disease and mortality in type 1 diabetes: the FinnDiane Study.
Peter Würtz; Mika Kähönen; Antti J Kangas; Terho Lehtimäki; Olli T Raitakari; Tapani Rönnemaa; Pasi Soininen; Jorma S Viikari; Mika Ala-Korpela
Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults.
Niku Oksala; Antti Reunanen; Ilkka Seppälä; Leo-Pekka Lyytikäinen; Kari-Matti Mäkelä; Mika Ala-Korpela; Jussi Hernesniemi; Antti Jula; Mika Kähönen; Terho Lehtimäki
Complementary prediction of cardiovascular events by estimated apo- and lipoprotein concentrations in the working age population. The Health 2000 Study.

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All Publications

2013: Ville-Petteri Mäkinen; O T Raitakari; M Savolainen; Pasi Soininen; Lena M Thorn; N Tolonen; J Viikari; Mika Ala-Korpela; Carol Forsblom; P-H Groop; A J Kangas
Triglyceride-cholesterol imbalance across lipoprotein subclasses predicts diabetic kidney disease and mortality in type 1 diabetes: the FinnDiane Study.
Journal of internal medicine 2013;273(4):383-95.
2013: Peter Würtz; Mika Kähönen; Antti J Kangas; Terho Lehtimäki; Olli T Raitakari; Tapani Rönnemaa; Pasi Soininen; Jorma S Viikari; Mika Ala-Korpela
Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults.
Diabetes care 2013;36(3):648-55.
2013: Niku Oksala; Antti Reunanen; Ilkka Seppälä; Leo-Pekka Lyytikäinen; Kari-Matti Mäkelä; Mika Ala-Korpela; Jussi Hernesniemi; Antti Jula; Mika Kähönen; Terho Lehtimäki
Complementary prediction of cardiovascular events by estimated apo- and lipoprotein concentrations in the working age population. The Health 2000 Study.
Annals of medicine 2013;45(2):141-8.
2013: Urho M Kujala; Terho Lehtimäki; Tuija H Leskinen; Ville-Petteri Mäkinen; Pekka Mäntyselkä; Paul F O'Reilly; Anneli Pouta; Paavo Rahkila; Olli T Raitakari; Markku J Savolainen; Sarianna Sipilä; Pasi Soininen; Tuija Tammelin; Risto Telama; Mauno Vanhala; Jorma Viikari; Peter Würtz; Sulin Cheng; Paul Elliott; Ilkka Heinonen; Mirja Hirvensalo; Marjo-Riitta Järvelin; Mika Kähönen; Heikki Kainulainen; Antti J Kangas; Jaakko Kaprio; Vuokko Kovanen; Mika Ala-Korpela
Long-term leisure-time physical activity and serum metabolome.
Circulation 2013;127(3):340-8.
2013: Olli T Raitakari; Veikko Salomaa; Markku J Savolainen; Tiina Solakivi; Jouko Sundvall; Jorma S A Viikari; Salim Yusuf; Sonia S Anand; Minna L Hannuksela; Jussi Hernesniemi; Matti Jauhiainen; Antti Jula; Markus Juonala; Mika Kähönen; Y Antero Kesäniemi; Petri T Kovanen; Terho Lehtimäki; Jaana Leiviskä; Britt-Marie Loo; Ville-Petteri Mäkinen; Jukka Marniemi; Matthew J McQueen; Ruby Miller; Jaakko Niemi; Markku Peltonen; Mika Ala-Korpela
Computationally estimated apolipoproteins B and A1 in predicting cardiovascular risk.
Atherosclerosis 2013;226(1):245-51.
2013: Michael R Skilton; Pasi Soininen; Leena Taittonen; Jorma S A Viikari; Peter Würtz; Kyra A Sim; Mika Ala-Korpela; David S Celermajer; Markus Juonala; Mika Kähönen; Antti J Kangas; Tomi Laitinen; Terho Lehtimäki; Vera Mikkilä; Olli T Raitakari
Fetal growth, omega-3 (n-3) fatty acids, and progression of subclinical atherosclerosis: preventing fetal origins of disease? The Cardiovascular Risk in Young Finns Study.
The American journal of clinical nutrition 2013;97(1):58-65.
2012: Ewa Szymańska; John P M van Duynhoven; Jacques Vervoort; Rob Vreeken; Johan Westerhuis; Antti J Kangas; Ian A Macdonald; David J Mela; Age K Smilde; Pasi Soininen; Katrin Strassburg; Mika Ala-Korpela; Jildau Bouwman; Doris M Jacobs
Gender-dependent associations of metabolite profiles and body fat distribution in a healthy population with central obesity: towards metabolomics diagnostics.
Omics : a journal of integrative biology 2012;16(12):652-67.
2012: J Wang; J Paananen; Pasi Soininen; A Stančáková; Mika Ala-Korpela; A J Kangas; J Kuusisto; Markku Laakso
Lipoprotein subclass profiles in individuals with varying degrees of glucose tolerance: a population-based study of 9399 Finnish men.
Journal of internal medicine 2012;272(6):562-72.
2012: Juha Koskinen; Terho Lehtimäki; Britt-Marie Loo; Costan G Magnussen; Markku Ahotupa; Mika Ala-Korpela; Antti Jula; Markus Juonala; Mika Kähönen; Antti J Kangas; Pasi Soininen; Jorma Sa Viikari; Peter Würtz; Olli T Raitakari
Apolipoprotein B, oxidized low-density lipoprotein, and LDL particle size in predicting the incidence of metabolic syndrome: the Cardiovascular Risk in Young Finns study.
European journal of preventive cardiology 2012;19(6):1296-303.
2012: J Vangipurapu; Pasi Soininen; A Stančáková; Mika Ala-Korpela; A J Kangas; T Kuulasmaa; J Kuusisto; M Laakso
Association between liver insulin resistance and cardiovascular risk factors.
Journal of internal medicine 2012;272(4):402-8.
2012: Peter Würtz; Markku J Savolainen; Pasi Soininen; Matti Tarkka; Russell Thomson; Tuulia Tynkkynen; Jorma S Viikari; Mika Ala-Korpela; Antti Jula; Markus Juonala; Mika Kähönen; Antti J Kangas; Pekka J Karhunen; Pekka Kuukasjärvi; Reino Laatikainen; Jari Laurikka; Terho Lehtimäki; Costan G Magnussen; Juho R Raiko; Olli T Raitakari
High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis.
European heart journal 2012;33(18):2307-16.
2012: Mauno Vanhala; Juha Saltevo; Pasi Soininen; Mika Ala-Korpela; Antti J Kangas; Hannu Kautiainen; Pekka Mäntyselkä
Serum omega-6 polyunsaturated fatty acids and the metabolic syndrome: a longitudinal population-based cohort study.
American journal of epidemiology 2012;176(3):253-60.
2012: Peter Würtz; Antti Jula; Mika Kähönen; Antti J Kangas; Sirkka Keinänen-Kiukaanniemi; Markku Laakso; Terho Lehtimäki; Ville-Petteri Mäkinen; Pekka Mäntyselkä; Juha Saltevo; Pasi Soininen; Mika Tiainen; Mauno Vanhala; Mika Ala-Korpela
Circulating metabolite predictors of glycemia in middle-aged men and women.
Diabetes care 2012;35(8):1749-56.
2012: Sanna M Kuusisto; Maria Laitinen; Ville-Petteri Mäkinen; Tomi Peltola; Tuire M Salonurmi; Markku Savolainen; Minna L Hannuksela; Pirjo Hedberg; Matti Jauhiainen; Linda S Kumpula; Mika Ala-Korpela
The interplay between lipoprotein phenotypes, adiponectin, and alcohol consumption.
Annals of medicine 2012;44(5):513-22.
2012: T Tukiainen; O Gröhn; Per-Henrik Groop; M Hallikainen; P Jylänki; Kimmo Kaski; M Kivipelto; Ville-Petteri Mäkinen; Tuula Pirttilä; Markku Savolainen; H Soininen; Pasi Soininen; Mika Ala-Korpela
Mild cognitive impairment associates with concurrent decreases in serum cholesterol and cholesterol-related lipoprotein subclasses.
The journal of nutrition, health & aging 2012;16(7):631-5.
2012: Pekka Mäntyselkä; Juha Saltevo; Pasi Soininen; Mika Ala-Korpela; Antti J Kangas; Hannu Kautiainen; Peter Würtz; Mauno Vanhala
Weight change and lipoprotein particle concentration and particle size: a cohort study with 6.5-year follow-up.
Atherosclerosis 2012;223(1):239-43.
2012: Alena Stancáková; Aldons J Lusis; Mario A Morken; Jussi Paananen; Päivi Pajukanta; Jussi Pihlajamäki; Niyas K Saleem; Pasi Soininen; Mika Ala-Korpela; Michael Boehnke; Lori L Bonnycastle; Henna Cederberg; Mete Civelek; Francis S Collins; Antti J Kangas; Johanna Kuusisto; Markku Laakso
Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men.
Diabetes 2012;61(7):1895-902.
2012: Peter Würtz; Marjo-Riitta Järvelin; Mika Kähönen; Antti J Kangas; Johannes Kettunen; Terho Lehtimäki; Ville-Petteri Mäkinen; Olli T Raitakari; Samuli Ripatti; Tapani Rönnemaa; Markku J Savolainen; Pasi Soininen; Tuija Tammelin; Taru Tukiainen; Jorma S Viikari; Mika Ala-Korpela
Metabolic signatures of insulin resistance in 7,098 young adults.
Diabetes 2012;61(6):1372-80.
2012: Taru Tukiainen; Jorma Viikari; Veikko Salomaa; Antti-Pekka Sarin; Markku J Savolainen; Pasi Soininen; Marja-Riitta Taskinen; Emmi Tikkanen; Mika Ala-Korpela; Johan G Eriksson; Marjo-Riitta Järvelin; Matti Jauhiainen; Antti Jula; Mika Kähönen; Antti J Kangas; Kimmo Kaski; Johannes Kettunen; Terho Lehtimäki; Leo-Pekka Lyytikäinen; Paul F O'Reilly; Aarno Palotie; Markus Perola; Anneli Pouta; Olli Raitakari; Samuli Ripatti
Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci.
Human molecular genetics 2012;21(6):1444-55.
2012: Ville-Petteri Mäkinen; Tomi Peltola; Pasi Soininen; Lena M Thorn; Tuulia Tynkkynen; Mika Ala-Korpela; Carol Forsblom; Antti J Kangas; Kimmo Kaski; Reino Laatikainen; Per-Henrik Groop
Metabolic diversity of progressive kidney disease in 325 patients with type 1 diabetes (the FinnDiane Study).
Journal of proteome research 2012;11(3):1782-90.
2012: Harri Niinikoski; Katja Pahkala; Mika Ala-Korpela; Eero Jokinen; Antti Jula; Hanna Lagström; Tapani Rönnemaa; Markku J Savolainen; Olli Simell; Jorma Viikari; Olli T Raitakari
Effect of repeated dietary counseling on serum lipoproteins from infancy to adulthood.
Pediatrics 2012;129(3):e704-13.
2012: Michael Inouye; Marjo-Riitta Järvelin; Mika Kähönen; Antti J Kangas; Johannes Kettunen; Pirkka-Pekka Laurila; Terho Lehtimäki; Leo-Pekka Lyytikäinen; Niku Oksala; Aarno Palotie; Markus Perola; Olli Raitakari; Samuli Ripatti; Veikko Salomaa; Markku J Savolainen; Pasi Soininen; Marja-Riitta Taskinen; Jorma Viikari; Mika Ala-Korpela; Paul I W de Bakker
Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
PLoS genetics 2012;8(8):e1002907.
2012: Mika Ala-Korpela; Antti J Kangas; Pasi Soininen
Quantitative high-throughput metabolomics: a new era in epidemiology and genetics.
Genome medicine 2012;4(4):36.
2011: Mika Ala-Korpela; Antti J Kangas; Michael Inouye
Genome-wide association studies and systems biology: together at last.
Trends in genetics : TIG 2011;27(12):493-8.
2011: Alena Stančáková; Jussi Paananen; Pasi Soininen; Antti J Kangas; Lori L Bonnycastle; Mario A Morken; Francis S Collins; Anne U Jackson; Michael L Boehnke; Johanna Kuusisto; Mika Ala-Korpela; Markku Laakso
Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men.
Diabetes 2011;60(5):1608-16.
2011: Blake E Haas; Daphna Weissglas-Volkov; Carlos Aguilar Salinas; Elina Nikkola; Laurent Vergnes; Ivette Cruz-Bautista; Laura Riba; Alena Stancakova; Johanna Kuusisto; Pasi Soininen; Antti J Kangas; Mika Ala-Korpela; Teresa Tusie-Luna; Markku Laakso; Päivi Pajukanta
Evidence of how rs7575840 influences apolipoprotein B-containing lipid particles.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(5):1201-7.
2011: Mauno Vanhala; Linda S Kumpula; Pasi Soininen; Antti J Kangas; Mika Ala-Korpela; Hannu Kautiainen; Pekka Mäntyselkä; Juha Saltevo
High serum adiponectin is associated with favorable lipoprotein subclass profile in 6.4-year follow-up.
European journal of endocrinology / European Federation of Endocrine Societies 2011;164(4):549-52.
2011: Peter Würtz; Pasi Soininen; Antti J Kangas; Ville-Petteri Mäkinen; Per-Henrik Groop; Markku Savolainen; Markus Juonala; Jorma S Viikari; Mika Kähönen; Terho Lehtimäki; Olli T Raitakari; Mika Ala-Korpela
Characterization of systemic metabolic phenotypes associated with subclinical atherosclerosis.
Molecular bioSystems 2011;7(2):385-93.
2011: Beatriz Valcárcel; Peter Würtz; Mika Ala-Korpela; Timothy M D Ebbels; Marjo-Riitta Järvelin; Antti J Kangas; Nafisa-Katrin Seich al Basatena; Pasi Soininen; Taru Tukiainen; Maria De Iorio
A differential network approach to exploring differences between biological states: an application to prediabetes.
PloS one 2011;6(9):e24702.
2011: Vibhor Kumar; Sarah J Butcher; Peter Engelhardt; Jukka Heikkonen; Kimmo Kaski; Mika Ala-Korpela; Katariina Öörni; Petri T Kovanen
Three-dimensional cryoEM reconstruction of native LDL particles to 16Å resolution at physiological body temperature.
PloS one 2011;6(5):e18841.
2010: Tiia Maria Kangas-Kontio; Anne Huotari; Heli Ruotsalainen; Karl-Heinz Herzig; Minna Tamminen; Mika Ala-Korpela; Markku Savolainen; Sakari Kakko
Genetic and environmental determinants of total and high-molecular weight adiponectin in families with low HDL-cholesterol and early onset coronary heart disease.
Atherosclerosis 2010;210(2):479-85.
2010: Linda S Kumpula; Sanna M Mäkelä; Ville-Petteri Mäkinen; Anna Karjalainen; Johanna M Liinamaa; Kimmo Kaski; Markku Savolainen; Minna L Hannuksela; Mika Ala-Korpela
Characterization of metabolic interrelationships and in silico phenotyping of lipoprotein particles using self-organizing maps.
Journal of lipid research 2010;51(2):431-9.
2010: Jatta Pirkola; Marja Vääräsmäki; Mika Ala-Korpela; Aini Bloigu; Dexter Canoy; Anna-Liisa Hartikainen; Maija Leinonen; Satu Miettola; Mika Paldanius; Tuija H Tammelin; Marjo-Riitta Järvelin; Anneli Pouta
Low-grade, systemic inflammation in adolescents: association with early-life factors, gender, and lifestyle.
American journal of epidemiology 2010;171(1):72-82.
2009: Katariina Lähdesmäki; Riia Plihtari; Pasi Soininen; Eva Hurt-Camejo; Mika Ala-Korpela; Katariina Öörni; Petri T Kovanen
Phospholipase A(2)-modified LDL particles retain the generated hydrolytic products and are more atherogenic at acidic pH.
Atherosclerosis 2009;207(2):352-9.
2009: Mika Ala-Korpela; Pasi Soininen; Markku Savolainen
Letter by Ala-Korpela et al regarding article, "Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women".
Circulation 2009;120(17):e149; author reply e150.
2009: Pasi Soininen; Antti J Kangas; Peter Würtz; Taru Tukiainen; Tuulia Tynkkynen; Reino Laatikainen; Marjo-Riitta Järvelin; Mika Kähönen; Terho Lehtimäki; Jorma Viikari; Olli T Raitakari; Markku Savolainen; Mika Ala-Korpela
High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism.
The Analyst 2009;134(9):1781-5.
2009: Timo Liimatainen; Juhana M Hakumäki; Risto A Kauppinen; Mika Ala-Korpela
Monitoring of gliomas in vivo by diffusion MRI and (1)H MRS during gene therapy-induced apoptosis: interrelationships between water diffusion and mobile lipids.
NMR in biomedicine 2009;22(3):272-9.
2009: Ville-Petteri Mäkinen; Carol Forsblom; Lena M Thorn; Johan Wadén; Kimmo Kaski; Mika Ala-Korpela; Per-Henrik Groop
Network of vascular diseases, death and biochemical characteristics in a set of 4,197 patients with type 1 diabetes (the FinnDiane Study).
Cardiovascular diabetology 2009;8():54.
2009: Jaakko Niemi; Ville-Petteri Mäkinen; Jukka Heikkonen; Leena Tenkanen; Yrjö Hiltunen; Minna L Hannuksela; Matti Jauhiainen; Carol Forsblom; Marja-Riitta Taskinen; Y Antero Kesäniemi; Markku Savolainen; Kimmo Kaski; Per-Henrik Groop; Petri T Kovanen; Mika Ala-Korpela
Estimation of VLDL, IDL, LDL, HDL2, apoA-I, and apoB from the Friedewald inputs--apoB and IDL, but not LDL, are associated with mortality in type 1 diabetes.
Annals of medicine 2009;41(6):451-61.
2008: Taru Tukiainen; Tuulia Tynkkynen; Ville-Petteri Mäkinen; Pasi Jylänki; Antti Kangas; Johanna Hokkanen; Aki Vehtari; Olli Gröhn; Merja Hallikainen; Hilkka Soininen; Miia Kivipelto; Per-Henrik Groop; Kimmo Kaski; Reino Laatikainen; Pasi Soininen; Tuula Pirttilä; Mika Ala-Korpela
A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's disease.
Biochemical and biophysical research communications 2008;375(3):356-61.
2008: Linda S Kumpula; Jussi M Kumpula; Marja-Riitta Taskinen; Matti Jauhiainen; Kimmo Kaski; Mika Ala-Korpela
Reconsideration of hydrophobic lipid distributions in lipoprotein particles.
Chemistry and physics of lipids 2008;155(1):57-62.
2008: Ville-Petteri Mäkinen; Carol Forsblom; Lena M Thorn; Johan Wadén; Daniel Gordin; Outi Heikkilä; Kustaa Hietala; Laura Kyllönen; Janne Kytö; Milla Rosengård-Bärlund; Markku Saraheimo; Nina Tolonen; Maija Parkkonen; Kimmo Kaski; Mika Ala-Korpela; Per-Henrik Groop
Metabolic phenotypes, vascular complications, and premature deaths in a population of 4,197 patients with type 1 diabetes.
Diabetes 2008;57(9):2480-7.
2008: Sanna M Mäkelä; Matti Jauhiainen; Mika Ala-Korpela; Jari Metso; Tiina M Lehto; Markku Savolainen; Minna L Hannuksela
HDL2 of heavy alcohol drinkers enhances cholesterol efflux from raw macrophages via phospholipid-rich HDL 2b particles.
Alcoholism, clinical and experimental research 2008;32(6):991-1000.
2008: Ville-Petteri Mäkinen; Pasi Soininen; Carol Forsblom; Maija Parkkonen; Petri Ingman; Kimmo Kaski; Per-Henrik Groop; Mika Ala-Korpela
1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death.
Molecular systems biology 2008;4():167.
2008: Mika Ala-Korpela
Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2008;46(1):27-42.
2007: Mika Ala-Korpela
Potential role of body fluid 1H NMR metabonomics as a prognostic and diagnostic tool.
Expert review of molecular diagnostics 2007;7(6):761-73.
2007: Teemu Suna; Aino Salminen; Pasi Soininen; Reino Laatikainen; Petri Ingman; Sanna Mäkelä; Markku Savolainen; Minna L Hannuksela; Matti Jauhiainen; Marja-Riitta Taskinen; Kimmo Kaski; Mika Ala-Korpela
1H NMR metabonomics of plasma lipoprotein subclasses: elucidation of metabolic clustering by self-organising maps.
NMR in biomedicine 2007;20(7):658-72.
2007: Pasi Soininen; Katariina Öörni; Hannu Maaheimo; Reino Laatikainen; Petri T Kovanen; Kimmo Kaski; Mika Ala-Korpela
1H NMR at 800 MHz facilitates detailed phospholipid follow-up during atherogenic modifications in low density lipoproteins.
Biochemical and biophysical research communications 2007;360(1):290-4.
2007: Mika Ala-Korpela; Niko Lankinen; Aino Salminen; Teemu Suna; Pasi Soininen; Reino Laatikainen; Petri Ingman; Matti Jauhiainen; Marja-Riitta Taskinen; Károly Héberger; Kimmo Kaski
The inherent accuracy of 1H NMR spectroscopy to quantify plasma lipoproteins is subclass dependent.
Atherosclerosis 2007;190(2):352-8.
2007: Aki Vehtari; Ville-Petteri Mäkinen; Pasi Soininen; Petri Ingman; Sanna M Mäkelä; Markku Savolainen; Minna L Hannuksela; Kimmo Kaski; Mika Ala-Korpela
A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic data.
BMC bioinformatics 2007;8 Suppl 2():S8.
2006: Ville-Petteri Mäkinen; Pasi Soininen; Carol Forsblom; Maija Parkkonen; Petri Ingman; Kimmo Kaski; Per-Henrik Groop; Mika Ala-Korpela
Diagnosing diabetic nephropathy by 1H NMR metabonomics of serum.
Magma (New York, N.Y.) 2006;19(6):281-96.
2006: Timo Liimatainen; Kimmo Kristian Lehtimäki; Mika Ala-Korpela; Juhana M Hakumäki
Identification of mobile cholesterol compounds in experimental gliomas by (1)H MRS in vivo: effects of ganciclovir-induced apoptosis on lipids.
FEBS letters 2006;580(19):4746-50.
2006: Mika Ala-Korpela; Petri Sipola; Kimmo Kaski
Characterization and molecular detection of atherothrombosis by magnetic resonance--potential tools for individual risk assessment and diagnostics.
Annals of medicine 2006;38(5):322-36.
2005: Katariina Öörni; Pirjo Posio; Mika Ala-Korpela; Matti Jauhiainen; Petri T Kovanen
Sphingomyelinase induces aggregation and fusion of small very low-density lipoprotein and intermediate-density lipoprotein particles and increases their retention to human arterial proteoglycans.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(8):1678-83.
2002: Taito Väänänen; Harri Koskela; Yrjö Hiltunen; Mika Ala-Korpela
Application of quantitative artificial neural network analysis to 2D NMR spectra of hydrocarbon mixtures.
Journal of chemical information and computer sciences 2002;42(6):1343-6.
2001: Kumar Changani; R Jalan; I Jane Cox; Mika Ala-Korpela; Kishore K Bhakoo; Simon D Taylor-Robinson; Jimmy D Bell
Evidence for altered hepatic gluconeogenesis in patients with cirrhosis using in vivo 31-phosphorus magnetic resonance spectroscopy.
Gut 2001;49(4):557-64.
2001: S Mierisová; Mika Ala-Korpela
MR spectroscopy quantitation: a review of frequency domain methods.
NMR in biomedicine 2001;14(4):247-59.
2001: Markku O Pentikäinen; Marja T Hyvönen; Katariina Öörni; T Hevonoja; Arja Korhonen; E M Lehtonen-Smeds; Mika Ala-Korpela; Petri T Kovanen
Altered phospholipid-apoB-100 interactions and generation of extra membrane material in proteolysis-induced fusion of LDL particles.
Journal of lipid research 2001;42(6):916-22.
2001: Marja T Hyvönen; Yrjö Hiltunen; W El-Deredy; T Ojala; J Vaara; Petri T Kovanen; Mika Ala-Korpela
Application of self-organizing maps in conformational analysis of lipids.
Journal of the American Chemical Society 2001;123(5):810-6.
2001: Marja T Hyvönen; Katariina Öörni; Petri T Kovanen; Mika Ala-Korpela
Changes in a phospholipid bilayer induced by the hydrolysis of a phospholipase A2 enzyme: a molecular dynamics simulation study.
Biophysical journal 2001;80(2):565-78.
2000: T Hevonoja; Markku O Pentikäinen; Marja T Hyvönen; Petri T Kovanen; Mika Ala-Korpela
Structure of low density lipoprotein (LDL) particles: basis for understanding molecular changes in modified LDL.
Biochimica et biophysica acta 2000;1488(3):189-210.
2000: Katariina Öörni; Markku O Pentikäinen; Mika Ala-Korpela; Petri T Kovanen
Aggregation, fusion, and vesicle formation of modified low density lipoprotein particles: molecular mechanisms and effects on matrix interactions.
Journal of lipid research 2000;41(11):1703-14.
2000: Markku O Pentikäinen; Katariina Öörni; Mika Ala-Korpela; Petri Kovanen
Modified LDL - trigger of atherosclerosis and inflammation in the arterial intima.
Journal of internal medicine 2000;247(3):359-70.
1999: Kumar Changani; Mika Ala-Korpela; Barry J Fuller; S Mierisova; DJ Bryant; Simon D Taylor-Robinson; Brian R Davidson; Jimmy D Bell
Incorporation of metabolite prior knowledge for data analysis: biochemical implications of dynamic 31P NMR ex vivo pig liver studies.
NMR in biomedicine 1999;12(4):197-204.
1999: Jukka K Hakala; Katariina Öörni; Mika Ala-Korpela; Petri T Kovanen
Lipolytic modification of LDL by phospholipase A2 induces particle aggregation in the absence and fusion in the presence of heparin.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1276-83.
1998: Katariina Öörni; Jukka K Hakala; A Annila; Mika Ala-Korpela; Petri T Kovanen
Sphingomyelinase induces aggregation and fusion, but phospholipase A2 only aggregation, of low density lipoprotein (LDL) particles. Two distinct mechanisms leading to increased binding strength of LDL to human aortic proteoglycans.
The Journal of biological chemistry 1998;273(44):29127-34.
1998: Arja Korhonen; M Jauhiainen; C Ehnholm; Petri T Kovanen; Mika Ala-Korpela
Remodeling of HDL by phospholipid transfer protein: demonstration of particle fusion by 1H NMR spectroscopy.
Biochemical and biophysical research communications 1998;249(3):910-6.
1998: Mika Ala-Korpela; Markku O Pentikäinen; Arja Korhonen; T Hevonoja; J Lounila; Petri T Kovanen
Detection of low density lipoprotein particle fusion by proton nuclear magnetic resonance spectroscopy.
Journal of lipid research 1998;39(8):1705-12.
1998: J Rico-Sanz; J V Hajnal; E Louise Thomas; S Mierisová; Mika Ala-Korpela; Jimmy D Bell
Intracellular and extracellular skeletal muscle triglyceride metabolism during alternating intensity exercise in humans.
The Journal of physiology 1998;510 ( Pt 2)():615-22.
1998: Geoffrey Haydon; R Jalan; Mika Ala-Korpela; Yrjö Hiltunen; J Hanley; LM Jarvis; C A Ludlum; Peter C Hayes
Prediction of cirrhosis in patients with chronic hepatitis C infection by artificial neural network analysis of virus and clinical factors.
Journal of viral hepatitis 1998;5(4):255-64.
1998: Jouni Kaartinen; Yrjö Hiltunen; Petri Kovanen; Mika Ala-Korpela
Application of self-organizing maps for the detection and classification of human blood plasma lipoprotein lipid profiles on the basis of 1H NMR spectroscopy data.
NMR in biomedicine 1998;11(4-5):168-76.
1997: Marja T Hyvönen; T T Rantala; Mika Ala-Korpela
Structure and dynamic properties of diunsaturated 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine lipid bilayer from molecular dynamics simulation.
Biophysical journal 1997;73(6):2907-23.
1997: Mika Ala-Korpela; Kumar Changani; Yrjö Hiltunen; Jimmy D Bell; B J Fuller; DJ Bryant; S D Taylor-Robinson; B R Davidson
Assessment of quantitative artificial neural network analysis in a metabolically dynamic ex vivo 31P NMR pig liver study.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1997;38(5):840-4.
1997: Arja Korhonen; Mika Ala-Korpela; M Johanna Liinamaa; Jukka Jokisaari; Y Antero Kesäniemi; Markku Savolainen
Assessment of cholesteryl ester transfer protein function in lipoprotein mixtures by 1H NMR spectroscopy.
NMR in biomedicine 1997;10(7):303-8.
1997: E Louise Thomas; JD Hanrahan; Mika Ala-Korpela; G Jenkinson; Denis Azzopardi; Richard A Iles; Jimmy D Bell
Noninvasive characterization of neonatal adipose tissue by 13C magnetic resonance spectroscopy.
Lipids 1997;32(6):645-51.
1997: Helena C Murphy; Mika Ala-Korpela; JJ White; A Raoof; Jimmy D Bell; ML Barnard; Shamus P Burns; Richard A Iles
Evidence for distinct behaviour of phosphatidylcholine and sphingomyelin at the low density lipoprotein surface.
Biochemical and biophysical research communications 1997;234(3):733-7.
1997: Kumar Changani; Barry J Fuller; DJ Bryant; Jimmy D Bell; Mika Ala-Korpela; Simon D Taylor-Robinson; D P Moore; Brian R Davidson
Non-invasive assessment of ATP regeneration potential of the preserved donor liver. A 31P MRS study in pig liver.
Journal of hepatology 1997;26(2):336-42.
1997: Helena C Murphy; A Raoof; JJ White; Mika Ala-Korpela; Jimmy D Bell; ML Barnard; Richard A Iles
Phospholipid headgroup mobility in low density lipoproteins.
Biochemical Society transactions 1997;25(1):22S.
1996: Mika Ala-Korpela; P Posio; S Mattila; Arja Korhonen; S R Williams
Absolute quantification of phospholipid metabolites in brain-tissue extracts by 1H NMR spectroscopy.
Journal of magnetic resonance. Series B 1996;113(2):184-9.
1996: Joseph V Hajnal; I Roberts; J Wilson; Angela Oatridge; Nadeem Saeed; I Jane Cox; Mika Ala-Korpela; Graeme M Bydder; Ian R Young
Effect of profound ischaemia on human muscle: MRI, phosphorus MRS and near-infrared studies.
NMR in biomedicine 1996;9(7):305-14.
1996: J P Usenius; S Tuohimetsä; Pauli Vainio; Mika Ala-Korpela; Yrjö Hiltunen; Risto A Kauppinen
Automated classification of human brain tumours by neural network analysis using in vivo 1H magnetic resonance spectroscopic metabolite phenotypes.
Neuroreport 1996;7(10):1597-600.
1996: Mika Ala-Korpela; Yrjö Hiltunen; Jimmy D Bell
Artificial neural network analysis of 1H nuclear magnetic resonance spectroscopic data from human plasma.
Anticancer research 1996;16(3B):1473-7.
1995: Mika Ala-Korpela; J P Usenius; J Keisala; A van den Boogaart; Pauli Vainio; J Jokisaari; Seppo Soimakallio; Risto A Kauppinen
Quantification of metabolites from single-voxel in vivo 1H NMR data of normal human brain by means of time-domain data analysis.
Magma (New York, N.Y.) 1995;3(3-4):129-36.
1995: Mika Ala-Korpela; Yrjö Hiltunen; Jimmy D Bell
Quantification of biomedical NMR data using artificial neural network analysis: lipoprotein lipid profiles from 1H NMR data of human plasma.
NMR in biomedicine 1995;8(6):235-44.
1995: Yrjö Hiltunen; E Heiniemi; Mika Ala-Korpela
Lipoprotein-lipid quantification by neural-network analysis of 1H NMR data from human blood plasma.
Journal of magnetic resonance. Series B 1995;106(2):191-4.
1994: Mika Ala-Korpela; Arja Korhonen; J Keisala; S Hörkkö; P Korpi; L P Ingman; J Jokisaari; Markku Savolainen; Y Antero Kesäniemi
1H NMR-based absolute quantitation of human lipoproteins and their lipid contents directly from plasma.
Journal of lipid research 1994;35(12):2292-304.
1994: A van den Boogaart; Mika Ala-Korpela; J Jokisaari; John R Griffiths
Time and frequency domain analysis of NMR data compared: an application to 1D 1H spectra of lipoproteins.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1994;31(4):347-58.
1993: Mika Ala-Korpela; Yrjö Hiltunen; J Jokisaari; Sinikka Eskelinen; K Kiviniity; Markku Savolainen; Y Antero Kesäniemi
A comparative study of 1H NMR lineshape fitting analyses and biochemical lipid analyses of the lipoprotein fractions VLDL, LDL and HDL, and total human blood plasma.
NMR in biomedicine 1993;6(3):225-33.
1992: Yrjö Hiltunen; Mika Ala-Korpela; J Jokisaari; Sinikka Eskelinen; K Kiviniitty
Proton nuclear magnetic resonance lineshape studies on human blood plasma lipids from newborn infants, healthy adults, and adults with tumors.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1992;26(1):89-99.
1991: Yrjö Hiltunen; Mika Ala-Korpela; J Jokisaari; Sinikka Eskelinen; K Kiviniitty; Markku Savolainen; Y Antero Kesäniemi
A lineshape fitting model for 1H NMR spectra of human blood plasma.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1991;21(2):222-32.