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John Barnett

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Miranda L Hanson; Ida Holásková; Rosana Schafer; Kathleen M Brundage; Meenal Elliott; John Barnett
Prenatal cadmium exposure alters postnatal immune cell development and function.
Miranda L Hanson; Kathleen M Brundage; Rosana Schafer; Janet C Tou; John Barnett
Prenatal cadmium exposure dysregulates sonic hedgehog and Wnt/beta-catenin signaling in the thymus resulting in altered thymocyte development.
John Barnett; Kathleen M Brundage
Evaluating macrophages in immunotoxicity testing.

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All Publications

2012: Miranda L Hanson; Ida Holásková; Rosana Schafer; Kathleen M Brundage; Meenal Elliott; John Barnett
Prenatal cadmium exposure alters postnatal immune cell development and function.
Toxicology and applied pharmacology 2012;261(2):196-203.
2010: Miranda L Hanson; Kathleen M Brundage; Rosana Schafer; Janet C Tou; John Barnett
Prenatal cadmium exposure dysregulates sonic hedgehog and Wnt/beta-catenin signaling in the thymus resulting in altered thymocyte development.
Toxicology and applied pharmacology 2010;242(2):136-45.
2010: John Barnett; Kathleen M Brundage
Evaluating macrophages in immunotoxicity testing.
Methods in molecular biology (Clifton, N.J.) 2010;598():75-94.
2010: Miranda L Hanson; Cody J Peer; Rodney Brundage; Patrick S Callery; Kathleen M Brundage; Rosana Schafer; Sergei Eremin; John Barnett
Subcellular localization of the amide class herbicide 3,4-dichloropropionanilide (DCPA) in T cells and hepatocytes.
Journal of toxicology and environmental health. Part A 2010;73(1):1-4.
2008: Keith D Salazar; irina ustyugova; Kathleen M Brundage; John Barnett; Rosana Schafer
A review of the immunotoxicity of the pesticide 3,4-dichloropropionanalide.
Journal of toxicology and environmental health. Part B, Critical reviews 2008;11(8):630-45.
2008: David J Klinke; irina ustyugova; Kathleen M Brundage; John Barnett
Modulating temporal control of NF-kappaB activation: implications for therapeutic and assay selection.
Biophysical journal 2008;94(11):4249-59.
2008: Tricia L Lewis; Kathleen M Brundage; Rodney A Brundage; John Barnett
3,4-Dichloropropionanilide (DCPA) inhibits T-cell activation by altering the intracellular calcium concentration following store depletion.
Toxicological sciences : an official journal of the Society of Toxicology 2008;103(1):97-107.
2008: Alexander M Rowe; Kathleen M Brundage; John Barnett
Developmental immunotoxicity of atrazine in rodents.
Basic & clinical pharmacology & toxicology 2008;102(2):139-45.
2007: Alexander M Rowe; Kathleen M Brundage; John Barnett
In vitro atrazine-exposure inhibits human natural killer cell lytic granule release.
Toxicology and applied pharmacology 2007;221(2):179-88.
2007: irina ustyugova; Laura L Frost; Knox Van Dyke; Kathleen M Brundage; Rosana Schafer; John Barnett
3,4-dichloropropionaniline suppresses normal macrophage function.
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(2):364-74.
2006: Keith D Salazar; Michael R Miller; John Barnett; Rosana Schafer
Evidence for a novel endocrine disruptor: the pesticide propanil requires the ovaries and steroid synthesis to enhance humoral immunity.
Toxicological sciences : an official journal of the Society of Toxicology 2006;93(1):62-74.
2006: James M Sheil; Marc A Frankenberry; Todd D Schell; Kathleen M Brundage; John Barnett
Propanil exposure induces delayed but sustained abrogation of cell-mediated immunity through direct interference with cytotoxic T-lymphocyte effectors.
Environmental health perspectives 2006;114(7):1059-64.
2006: Alexander M Rowe; Kathleen M Brundage; Rosana Schafer; John Barnett
Immunomodulatory effects of maternal atrazine exposure on male Balb/c mice.
Toxicology and applied pharmacology 2006;214(1):69-77.
2006: Bing-Hua Jiang; Ling-Zhi Liu; Rosana Schafer; Daniel C Flynn; John Barnett
A novel role for 3, 4-dichloropropionanilide (DCPA) in the inhibition of prostate cancer cell migration, proliferation, and hypoxia-inducible factor 1alpha expression.
BMC cancer 2006;6():204.
2005: Keith D Salazar; Patricia de la Rosa; John Barnett; Rosana Schafer
The polysaccharide antibody response after Streptococcus pneumoniae vaccination is differentially enhanced or suppressed by 3,4-dichloropropionanilide and 2,4-dichlorophenoxyacetic acid.
Toxicological sciences : an official journal of the Society of Toxicology 2005;87(1):123-33.
2005: Patricia de la Rosa; John Barnett; Rosana Schafer
Characterization of thymic atrophy and the mechanism of thymocyte depletion after in vivo exposure to a mixture of herbicides.
Journal of toxicology and environmental health. Part A 2005;68(2):81-98.
2004: Lee S F Soderberg; Usha Ponnappan; A Roy; R Schafer; John Barnett
Production of macrophage IL-1beta was inhibited both at the levels of transcription and maturation by caspase-1 following inhalation exposure to isobutyl nitrite.
Toxicology letters 2004;152(1):47-56.
2004: Kathleen M Brundage; Rosana Schafer; John Barnett
Altered AP-1 (activating protein-1) activity and c-jun activation in T cells exposed to the amide class herbicide 3,4-dichloropropionanilide (DCPA).
Toxicological sciences : an official journal of the Society of Toxicology 2004;79(1):98-105.
2003: Kathleen M Brundage; John Barnett; James E Mahaney
The amide class herbicide 3,4-dichloropropionanilide (DCPA) alters the mobility of hydrocarbon chains in T-lymphocyte but not macrophage membranes.
Journal of toxicology and environmental health. Part A 2003;66(23):2253-65.
2001: L L Frost; Y X Neeley; Rosana Schafer; Laura F Gibson; John Barnett
Propanil inhibits tumor necrosis factor-alpha production by reducing nuclear levels of the transcription factor nuclear factor-kappab in the macrophage cell line ic-21.
Toxicology and applied pharmacology 2001;172(3):186-93.
2000: V A Watson; John Barnett; Rosana Schafer
In vivo cytokine production and resistance to infection after acute exposure to 3,4-dichloropropionaniline.
Journal of toxicology and environmental health. Part A 2000;60(6):391-406.
2000: G L Guo; D Rose; JT Flick; John Barnett; Lee S F Soderberg
Acute exposure to the abused inhalant, isobutyl nitrite, reduced T cell responsiveness and spleen cellularity.
Toxicology letters 2000;116(1-2):151-8.
2000: Lee S F Soderberg; A Roy; JT Flick; John Barnett
Nitrite inhalants spontaneously liberate nitric oxide, which is not responsible for the immunotoxicity in C57BL/6 mice.
International journal of immunopharmacology 2000;22(2):151-7.
1999: W Zhao; Rosana Schafer; John Barnett
Propanil affects transcriptional and posttranscriptional regulation of IL-2 expression in activated EL-4 cells.
Toxicology and applied pharmacology 1999;154(2):153-9.
1998: W Zhao; Rosana Schafer; John Barnett
Cytokine production by C57BL/6 mouse spleen cells is selectively reduced by exposure to propanil.
Journal of toxicology and environmental health. Part A 1998;55(2):107-20.
1998: Christopher F Cuff; Jonathan R Fulton; John Barnett; Christopher Boyce
Enteric reovirus infection as a probe to study immunotoxicity of the gastrointestinal tract.
Toxicological sciences : an official journal of the Society of Toxicology 1998;42(2):99-108.
1998: Lee S F Soderberg; A Roy; John Barnett
Isobutyl nitrite liberates nitric oxide which is not responsible for the immunotoxicity of the inhalant.
Advances in experimental medicine and biology 1998;437():265-8.
1997: John Barnett
Age-related susceptibility to immunotoxicants: animal data and human parallels.
Environmental toxicology and pharmacology 1997;4(3-4):315-21.
1997: Y C Xie; Rosana Schafer; John Barnett
The immunomodulatory effects of the herbicide propanil on murine macrophage interleukin-6 and tumor necrosis factor-alpha production.
Toxicology and applied pharmacology 1997;145(1):184-91.
1997: Y C Xie; Rosana Schafer; John Barnett
Inhibitory effect of 3,4-dichloro-propionaniline on cytokine production by macrophages is associated with LPS-mediated signal transduction.
Journal of leukocyte biology 1997;61(6):745-52.
1996: Lee S F Soderberg; L W Chang; John Barnett
Elevated TNF-alpha and inducible nitric oxide production by alveolar macrophages after exposure to a nitrite inhalant.
Journal of leukocyte biology 1996;60(4):459-64.
1996: Christopher F Cuff; W Zhao; T Nukui; Rosana Schafer; John Barnett
3,4-Dichloropropionanilide-induced atrophy of the thymus: mechanisms of toxicity and recovery.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1996;33(1):83-90.
1996: Lee S F Soderberg; JT Flick; John Barnett
Leukopenia and altered hematopoietic activity in mice exposed to the abused inhalant, isobutyl nitrite.
Experimental hematology 1996;24(7):848-53.
1996: Lee S F Soderberg; L W Chang; John Barnett
Inhaled isobutyl nitrite produced lung inflammation with increased macrophage TNF-alpha and nitric oxide production.
Advances in experimental medicine and biology 1996;402():187-9.
1995: W Zhao; Rosana Schafer; Christopher F Cuff; J Gandy; John Barnett
Changes in primary and secondary lymphoid organ T-cell subpopulations resulting from acute in vivo exposure to propanil.
Journal of toxicology and environmental health 1995;46(2):171-81.
1995: Lee S F Soderberg; John Barnett
Inhalation exposure to isobutyl nitrite inhibits macrophage tumoricidal activity and modulates inducible nitric oxide.
Journal of leukocyte biology 1995;57(1):135-40.
1995: Lee S F Soderberg; John Barnett
Possible mechanisms of immunotoxicity following in vivo exposure to the inhalant, isobutyl nitrite.
Advances in experimental medicine and biology 1995;373():189-92.
1994: G Blyler; K S Landreth; John Barnett
Gender-specific effects of prenatal chlordane exposure on myeloid cell development.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1994;23(2):188-93.
1994: G Blyler; K S Landreth; T Lillis; Rosana Schafer; S A Theus; J Gandy; John Barnett
Selective myelotoxicity of propanil.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1994;22(4):505-10.
1993: Lee S F Soderberg; John Barnett
Inhaled isobutyl nitrite compromises T-dependent, but not T-independent, antibody induction.
International journal of immunopharmacology 1993;15(7):821-7.
1993: Lee S F Soderberg; John Barnett
Exposure to the abused inhalant, isobutyl nitrite, compromises both antibody and cell-mediated immunity.
Advances in experimental medicine and biology 1993;335():265-8.
1993: S A Theus; D R Tabor; J Gandy; John Barnett
Alteration of macrophage cytotoxicity through endogenous interferon and tumor necrosis factor alpha induction by propanil.
Toxicology and applied pharmacology 1993;118(1):46-52.
1992: S C Moore; S A Theus; John Barnett; Lee S F Soderberg
Bone marrow natural suppressor cells inhibit the growth of myeloid progenitor cells and the synthesis of colony-stimulating factors.
Experimental hematology 1992;20(10):1178-83.
1992: S A Theus; D R Tabor; Lee S F Soderberg; John Barnett
Macrophage tumoricidal mechanisms are selectively altered by prenatal chlordane exposure.
Agents and actions 1992;37(1-2):140-6.
1992: D R Tabor; S A Theus; John Barnett; Richard F Jacobs
Macrophage membrane glycoprotein binding of Griffonia simplicifolia I-B4 induces TNF-alpha production and a tumoricidal response.
Journal of cellular physiology 1992;152(3):500-6.
1992: S C Moore; S A Theus; John Barnett; Lee S F Soderberg
Cytokine regulation of bone marrow natural suppressor cell activity in the suppression of lymphocyte function.
Cellular immunology 1992;141(2):398-408.
1992: John Barnett; J Gandy; D Wilbourn; S A Theus
Comparison of the immunotoxicity of propanil and its metabolite, 3,4-dichloroaniline, in C57Bl/6 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1992;18(4):628-31.
1992: S A Theus; K A Lau; D R Tabor; Lee S F Soderberg; John Barnett
In vivo prenatal chlordane exposure induces development of endogenous inflammatory macrophages.
Journal of leukocyte biology 1992;51(4):366-72.
1992: D R Tabor; S A Theus; John Barnett; A Francine Tryka; Richard F Jacobs
The concurrent expression of Griffonia simplicifolia-IB4 binding and tumor necrosis factor-alpha differs between alveolar and peritoneal macrophages.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992;199(3):351-9.
1991: Lee S F Soderberg; John Barnett
Exposure to inhaled isobutyl nitrite reduces T cell blastogenesis and antibody responsiveness.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1991;17(4):821-4.
1991: Lee S F Soderberg; John Barnett; L W Chang
Inhaled isobutyl nitrite impairs T cell reactivity.
Advances in experimental medicine and biology 1991;288():265-8.
1990: John Barnett; B L Blaylock; J Gandy; J H Menna; R Denton; Lee S F Soderberg
Alteration of fetal liver colony formation by prenatal chlordane exposure.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;15(4):820-2.
1990: Lee S F Soderberg; John Barnett; M L Baker; H Salari; J R Sorenson
Postirradiation treatment with copper(II)2(3,5-diisopropylsalicylate)4 enhances radiation recovery and hemopoietic regeneration.
Experimental hematology 1990;18(7):801-5.
1990: John Barnett; B L Blaylock; J Gandy; J H Menna; R Denton; Lee S F Soderberg
Long-term alteration of adult bone marrow colony formation by prenatal chlordane exposure.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1990;14(4):688-95.
1990: B L Blaylock; Lee S F Soderberg; J Gandy; J H Menna; R Denton; John Barnett
Cytotoxic T-lymphocyte and NK responses in mice treated prenatally with chlordane.
Toxicology letters 1990;51(1):41-9.
1990: J J Sorenson; Lee S F Soderberg; M L Baker; John Barnett; L W Chang; H Salari; W M Willingham
Radiation recovery agents: Cu(II), Mn(II), Zn(II), or Fe(III) 3,5-diisopropylsalicylate complexes facilitate recovery from ionizing radiation induced radical mediated tissue damage.
Advances in experimental medicine and biology 1990;264():69-77.
1989: John Barnett; J Gandy
Effect of acute propanil exposure on the immune response of C57Bl/6 mice.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1989;12(4):757-64.
1989: Lee S F Soderberg; John Barnett; J R Sorenson
Copper complexes stimulate hemopoiesis and lymphopoiesis.
Advances in experimental medicine and biology 1989;258():209-17.
1988: Lee S F Soderberg; John Barnett; M L Baker; L W Chang; H Salari; J R Sorenson
Copper(II)2(3,5-diisopropylsalicylate)4 stimulates hemopoiesis in normal and irradiated mice.
Experimental hematology 1988;16(7):577-80.
1987: John Barnett; L Barfield; R Walls; R Joyner; R Owens; Lee S F Soderberg
The effect of in utero exposure to hexachlorobenzene on the developing immune response of BALB/c mice.
Toxicology letters 1987;39(2-3):263-74.
1987: Lee S F Soderberg; John Barnett; M L Baker; H Salari; R J Sorenson
Copper(II)(3,5-diisopropylsalicylate)2 accelerates recovery of B and T cell reactivity following irradiation.
Scandinavian journal of immunology 1987;26(5):495-502.
1985: John Barnett; D Holcomb; J H Menna; Lee S F Soderberg
The effect of prenatal chlordane exposure on specific anti-influenza cell-mediated immunity.
Toxicology letters 1985;25(3):229-38.
1985: John Barnett; Lee S F Soderberg; J H Menna
The effect of prenatal chlordane exposure on the delayed hypersensitivity response of BALB/c mice.
Toxicology letters 1985;25(2):173-83.
1985: M Beggs; J H Menna; John Barnett
Effect of chlordane on influenza type A virus and herpes simplex type 1 virus replication in vitro.
Journal of toxicology and environmental health 1985;16(2):173-88.
1985: J H Menna; John Barnett; Lee S F Soderberg
Influenza type A virus infection of mice exposed in utero to chlordane; survival and antibody studies.
Toxicology letters 1985;24(1):45-52.
1984: John Barnett; J H Menna
The effect of percutaneously applied corn oil on the humoral immune response of the suckling mouse.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 1984;5(4-5):353-6.