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Steven Birken

Research Profile

Chemicals & Drugs

Physiology

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Publications

TOP 3
Ulf-Håkan Stenman; Steven Birken; Kristina Hotakainen; Anna Lempiäinen; Henrik Alfthan
Elimination of complement interference in immunoassay of hyperglycosylated human chorionic gonadotropin.
Mishaela R Rubin; John P Bilezikian; Steven Birken; Shonni J Silverberg
Human chorionic gonadotropin measurements in parathyroid carcinoma.
Steven Birken; Ruth McChesney; Oksana Yershova; John Gaughan; Kim Pettersson; Geoff Rechenberg; Chung H Wu; George Taliadouros
Patterns of LHbetacf among women in health and disease.

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All Publications

2011: Ulf-Håkan Stenman; Steven Birken; Kristina Hotakainen; Anna Lempiäinen; Henrik Alfthan
Elimination of complement interference in immunoassay of hyperglycosylated human chorionic gonadotropin.
Clinical chemistry 2011;57(7):1075-7.
2008: Mishaela R Rubin; John P Bilezikian; Steven Birken; Shonni J Silverberg
Human chorionic gonadotropin measurements in parathyroid carcinoma.
European journal of endocrinology / European Federation of Endocrine Societies 2008;159(4):469-74.
2007: Steven Birken; Ruth McChesney; Oksana Yershova; John Gaughan; Kim Pettersson; Geoff Rechenberg; Chung H Wu; George Taliadouros
Patterns of LHbetacf among women in health and disease.
Molecular and cellular endocrinology 2007;260-262():172-82.
2007: Lisa S Kelly; Steven Birken; J David Puett
Determination of hyperglycosylated human chorionic gonadotropin produced by malignant gestational trophoblastic neoplasias and male germ cell tumors using a lectin-based immunoassay and surface plasmon resonance.
Molecular and cellular endocrinology 2007;260-262():33-9.
2006: Leena Valmu; Henrik Alfthan; Kristina Hotakainen; Steven Birken; Ulf-Hakan Stenman
Site-specific glycan analysis of human chorionic gonadotropin beta-subunit from malignancies and pregnancy by liquid chromatography--electrospray mass spectrometry.
Glycobiology 2006;16(12):1207-18.
2005: Steven Birken
Specific measurement of o-linked core 2 sugar-containing isoforms of hyperglycosylated human chorionic gonadotropin by antibody b152.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2005;26(3):131-41.
2005: Ruth McChesney; Allen J Wilcox; John F O'Connor; Clarice R Weinberg; Donna D Baird; John P Schlatterer; D Robert McConnaughey; Steven Birken; Robert E Canfield
Intact HCG, free HCG beta subunit and HCG beta core fragment: longitudinal patterns in urine during early pregnancy.
Human reproduction (Oxford, England) 2005;20(4):928-35.
2005: Adrian Bristow; Peter Berger; Jean-Michel Bidart; Steven Birken; Robert Norman; Ulf-Hakan Stenman; Catharine Sturgeon
Establishment, value assignment, and characterization of new WHO reference reagents for six molecular forms of human chorionic gonadotropin.
Clinical chemistry 2005;51(1):177-82.
2003: Steven Birken; Oksana Yershova; Rebecca V Myers; Michael P Bernard; William R Moyle
Analysis of human choriogonadotropin core 2 o-glycan isoforms.
Molecular and cellular endocrinology 2003;204(1-2):21-30.
2003: Steven Birken; Peter Berger; Jean-Michel Bidart; Matthias Weber; Adrian Bristow; Rob Norman; Catharine Sturgeon; Ulf-Hakan Stenman
Preparation and characterization of new WHO reference reagents for human chorionic gonadotropin and metabolites.
Clinical chemistry 2003;49(1):144-54.
2002: G Kovalevskaya; Steven Birken; T Kakuma; N Ozaki; M Sauer; S Lindheim; M Cohen; A Kelly; John P Schlatterer; John F O'Connor
Differential expression of human chorionic gonadotropin (hCG) glycosylation isoforms in failing and continuing pregnancies: preliminary characterization of the hyperglycosylated hCG epitope.
The Journal of endocrinology 2002;172(3):497-506.
2002: P Berger; C Sturgeon; J M Bidart; E Paus; R Gerth; M Niang; Adrian Bristow; Steven Birken; Ulf-Hakan Stenman
The ISOBM TD-7 Workshop on hCG and related molecules. Towards user-oriented standardization of pregnancy and tumor diagnosis: assignment of epitopes to the three-dimensional structure of diagnostically and commercially relevant monoclonal antibodies directed against human chorionic gonadotropin and derivatives.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2002;23(1):1-38.
2001: Steven Birken; G Kovalevskaya; J O'Connor
Immunochemical measurement of early pregnancy isoforms of HCG: potential applications to fertility research, prenatal diagnosis, and cancer.
Archives of medical research 2001;32(6):635-43.
2001: Steven Birken; Mary Ann Gawinowicz; Y Maydelman; Yelena Milgrom
Metabolism of gonadotropins: comparisons of the primary structures of the human pituitary and urinary LH beta cores and the chimpanzee CG beta core demonstrate universality of core production.
The Journal of endocrinology 2001;171(1):131-41.
2000: Steven Birken; Y Maydelman; Mary Ann Gawinowicz
Preparation and analysis of the common urinary forms of human chorionic gonadotropin.
Methods (San Diego, Calif.) 2000;21(1):3-14.
1999: John F O'Connor; G Kovalevskaya; Steven Birken
Interference of luteinizing hormone beta-core fragment in urinary gonadotropin assays.
Clinical chemistry 1999;45(12):2290-2.
1999: Steven Birken; A Krichevsky; J O'Connor; John P Schlatterer; L Cole; A Kardana; Robert E Canfield
Development and characterization of antibodies to a nicked and hyperglycosylated form of hCG from a choriocarcinoma patient: generation of antibodies that differentiate between pregnancy hCG and choriocarcinoma hCG.
Endocrine 1999;10(2):137-44.
1999: G Kovalevskaya; Steven Birken; T Kakuma; John F O'Connor
Early pregnancy human chorionic gonadotropin (hCG) isoforms measured by an immunometric assay for choriocarcinoma-like hCG.
The Journal of endocrinology 1999;161(1):99-106.
1999: Steven Birken; Nanette Santoro; Y Maydelman; G Kovalevskaya; Rogerio A Lobo; E W Freeman; M Warren; Don McMahon; J O'Connor
Differences in urinary excretion patterns of the hLH beta core fragment in premenopausal, perimenopausal, and postmenopausal women.
Menopause (New York, N.Y.) 1999;6(4):290-8.
1999: G Kovalevskaya; Steven Birken; T Kakuma; John P Schlatterer; John F O'Connor
Evaluation of nicked human chorionic gonadotropin content in clinical specimens by a specific immunometric assay.
Clinical chemistry 1999;45(1):68-77.
1998: John F O'Connor; G Kovalevskaya; Steven Birken; John P Schlatterer; Daniel S Schechter; D J McMahon; Robert E Canfield
The expression of the urinary forms of human luteinizing hormone beta fragment in various populations as assessed by a specific immunoradiometric assay.
Human reproduction (Oxford, England) 1998;13(4):826-35.
1998: Y Lunardi-Iskandar; Joseph L Bryant; William A Blattner; C L Hung; L Flamand; P Gill; Philippe Hermans; Steven Birken; Robert C Gallo
Effects of a urinary factor from women in early pregnancy on HIV-1, SIV and associated disease.
Nature medicine 1998;4(4):428-34.
1996: Steven Birken; G Kovalevskaya; J O'Connor
Metabolism of hCG and hLH to multiple urinary forms.
Molecular and cellular endocrinology 1996;125(1-2):121-31.
1996: Joyce W Lustbader; Steven Birken; Susan Pollak; A Pound; Brian T Chait; U A Mirza; S Ramnarain; Robert E Canfield; J M Brown
Expression of human chorionic gonadotropin uniformly labeled with NMR isotopes in Chinese hamster ovary cells: an advance toward rapid determination of glycoprotein structures.
Journal of biomolecular NMR 1996;7(4):295-304.
1996: Steven Birken; Y Maydelman; M A Gawinowicz; A Pound; Y Liu; A S Hartree
Isolation and characterization of human pituitary chorionic gonadotropin.
Endocrinology 1996;137(4):1402-11.
1995: G Kovalevskaya; Steven Birken; J O'Connor; John P Schlatterer; Y Maydelman; Robert E Canfield
HLH beta core fragment immunoreactivity in the urine of ovulating women: a sensitive and specific immunometric assay for its detection.
Endocrine 1995;3(12):881-7.
1995: Joyce W Lustbader; H Wu; Steven Birken; Susan Pollak; M A Gawinowicz Kolks; A M Pound; D Austen; Wayne A Hendrickson; Robert E Canfield
The expression, characterization, and crystallization of wild-type and selenomethionyl human chorionic gonadotropin.
Endocrinology 1995;136(2):640-50.
1994: John F O'Connor; Steven Birken; Joyce W Lustbader; A Krichevsky; Y Chen; Robert E Canfield
Recent advances in the chemistry and immunochemistry of human chorionic gonadotropin: impact on clinical measurements.
Endocrine reviews 1994;15(5):650-83.
1994: A Krichevsky; Steven Birken; J O'Connor; H F Acevedo; K Bikel; Joyce W Lustbader; A Hartree; Robert E Canfield
Development, characterization, and application of monoclonal antibodies to the native and synthetic beta COOH-terminal portion of human chorionic gonadotropin (hCG) that distinguish between the native and desialylated forms of hCG.
Endocrinology 1994;134(3):1139-45.
1993: Steven Birken; Y Chen; M A Gawinowicz; G M Agosto; Robert E Canfield; A S Hartree
Structure and significance of human luteinizing hormone-beta core fragment purified from human pituitary extracts.
Endocrinology 1993;133(3):985-9.
1993: Steven Birken; Y Chen; M A Gawinowicz; Joyce W Lustbader; Susan Pollak; G Agosto; R Buck; J O'Connor
Separation of nicked human chorionic gonadotropin (hCG), intact hCG, and hCG beta fragment from standard reference preparations and raw urine samples.
Endocrinology 1993;133(3):1390-7.
1993: Joyce W Lustbader; D L Yarmush; Steven Birken; J David Puett; Robert E Canfield
The application of chemical studies of human chorionic gonadotropin to visualize its three-dimensional structure.
Endocrine reviews 1993;14(3):291-311.
1993: Ulf-Hakan Stenman; J M Bidart; Steven Birken; K Mann; B Nisula; J O'Connor
Standardization of protein immunoprocedures. Choriogonadotropin (CG).
Scandinavian journal of clinical and laboratory investigation. Supplementum 1993;216():42-78.
1993: Jean-Michel Bidart; Steven Birken; P Berger; A Krichevsky
Immunochemical mapping of hCG and hCG-related molecules.
Scandinavian journal of clinical and laboratory investigation. Supplementum 1993;216():118-36.
1991: Laurence A Cole; A Kardana; F C Ying; Steven Birken
The biological and clinical significance of nicks in human chorionic gonadotropin and its free beta-subunit.
The Yale journal of biology and medicine 1991;64(6):627-37.
1991: A Kardana; M M Elliott; M A Gawinowicz; Steven Birken; Laurence A Cole
The heterogeneity of human chorionic gonadotropin (hCG). I. Characterization of peptide heterogeneity in 13 individual preparations of hCG.
Endocrinology 1991;129(3):1541-50.
1991: Laurence A Cole; A Kardana; P Andrade-Gordon; M A Gawinowicz; J C Morris; E R Bergert; J O'Connor; Steven Birken
The heterogeneity of human chorionic gonadotropin (hCG). III. The occurrence and biological and immunological activities of nicked hCG.
Endocrinology 1991;129(3):1559-67.
1991: Steven Birken; M A Gawinowicz; A Kardana; Laurence A Cole
The heterogeneity of human chorionic gonadotropin (hCG). II. Characteristics and origins of nicks in hCG reference standards.
Endocrinology 1991;129(3):1551-8.
1991: M A Gawinowicz; G Merlini; Steven Birken; E F Osserman; E A Kabat
Amino acid sequence of the FV region of a human monoclonal IgM (NOV) with specificity for the capsular polysaccharide of the group B meningococcus and of Escherichia coli K1, which cross-reacts with polynucleotides and with denatured DNA.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(3):915-20.
1991: A Krichevsky; Steven Birken; J O'Connor; K Bikel; John P Schlatterer; C Yi; G Agosto; Robert E Canfield
Development and characterization of a new, highly specific antibody to the human chorionic gonadotropin-beta fragment.
Endocrinology 1991;128(3):1255-64.
1990: Susan Pollak; S Halpine; Brian T Chait; Steven Birken
High resolution high performance liquid chromatography fingerprinting of purified human chorionic gonadotropin demonstrates that oxidation is a cause of hormone heterogeneity.
Endocrinology 1990;126(1):199-208.
1989: Joyce W Lustbader; Steven Birken; N F Pileggi; M A Kolks; Susan Pollak; M E Cuff; W Yang; Wayne A Hendrickson; Robert E Canfield
Crystallization and characterization of human chorionic gonadotropin in chemically deglycosylated and enzymatically desialylated states.
Biochemistry 1989;28(24):9239-43.
1988: Laurence A Cole; Steven Birken
Origin and occurrence of human chorionic gonadotropin beta-subunit core fragment.
Molecular endocrinology (Baltimore, Md.) 1988;2(9):825-30.
1988: Jean-Michel Bidart; Frédéric Troalen; G R Bousfield; Steven Birken; Dominique Bellet
Antigenic determinants on human choriogonadotropin alpha-subunit. I. Characterization of topographic sites recognized by monoclonal antibodies.
The Journal of biological chemistry 1988;263(21):10364-9.
1988: A Krichevsky; Glenn Armstrong; John P Schlatterer; Steven Birken; J O'Connor; K Bikel; S Silverberg; Joyce W Lustbader; Robert E Canfield
Preparation and characterization of antibodies to the urinary fragment of the human chorionic gonadotropin beta-subunit.
Endocrinology 1988;123(1):584-93.
1988: Steven Birken; Glenn Armstrong; M A Kolks; Laurence A Cole; G M Agosto; A Krichevsky; J L Vaitukaitis; Robert E Canfield
Structure of the human chorionic gonadotropin beta-subunit fragment from pregnancy urine.
Endocrinology 1988;123(1):572-83.
1988: Steven Birken; G Agosto; S Amr; B Nisula; L Cole; J Lewis; Robert E Canfield
Characterization of antisera distinguishing carbohydrate structures in the beta-carboxyl-terminal region of human chorionic gonadotropin.
Endocrinology 1988;122(5):2054-63.
1988: John F O'Connor; John P Schlatterer; Steven Birken; A Krichevsky; Glenn Armstrong; Don McMahon; Robert E Canfield
Development of highly sensitive immunoassays to measure human chorionic gonadotropin, its beta-subunit, and beta core fragment in the urine: application to malignancies.
Cancer research 1988;48(5):1361-6.
1988: L Liu; R E Wehmann; C Rosa; Steven Birken; B C Nisula
Serum testosterone response to desialylated human choriogonadotropin in man.
Journal of andrology 1988;9(1):62-6.
1987: Joyce W Lustbader; Steven Birken; Susan Pollak; L Levinson; E Bernstine; N Hsiung; Robert E Canfield
Characterization of the expression products of recombinant human choriogonadotropin and subunits.
The Journal of biological chemistry 1987;262(29):14204-12.
1987: Robert E Canfield; John F O'Connor; Steven Birken; A Krichevsky; Allen J Wilcox
Development of an assay for a biomarker of pregnancy and early fetal loss.
Environmental health perspectives 1987;74():57-66.
1987: Steven Birken; M A Kolks; S Amr; B Nisula; J David Puett
Structural and functional studies of the tryptic core of the human chorionic gonadotropin beta-subunit.
Endocrinology 1987;121(2):657-66.
1987: S Imamura; Glenn Armstrong; Steven Birken; Laurence A Cole; Robert E Canfield
Detection of desialylated forms of human chorionic gonadotropin.
Clinica chimica acta; international journal of clinical chemistry 1987;163(3):339-49.
1986: Steven Birken; M A Gawinowicz Kolks; S Amr; B Nisula; J David Puett
Tryptic digestion of the alpha subunit of human choriogonadotropin.
The Journal of biological chemistry 1986;261(23):10719-27.
1985: S Amr; C Rosa; Steven Birken; Robert E Canfield; B Nisula
Carboxyterminal peptide fragments of the beta subunit are urinary products of the metabolism of desialylated human choriogonadotropin.
The Journal of clinical investigation 1985;76(1):350-6.
1985: P H Ehrlich; Z A Moustafa; A Krichevsky; Steven Birken; Glenn Armstrong; Robert E Canfield
Characterization and relative orientation of epitopes for monoclonal antibodies and antisera to human chorionic gonadotropin.
American journal of reproductive immunology and microbiology : AJRIM 1985;8(2):48-54.
1984: C Rosa; S Amr; Steven Birken; R Wehmann; B Nisula
Effect of desialylation of human chorionic gonadotropin on its metabolic clearance rate in humans.
The Journal of clinical endocrinology and metabolism 1984;59(6):1215-9.
1984: Glenn Armstrong; P H Ehrlich; Steven Birken; John P Schlatterer; Ethel S Siris; W C Hembree; Robert E Canfield
Use of a highly sensitive and specific immunoradiometric assay for detection of human chorionic gonadotropin in urine of normal, nonpregnant, and pregnant individuals.
The Journal of clinical endocrinology and metabolism 1984;59(5):867-74.
1984: S R Lentz; Steven Birken; Joyce W Lustbader; I Boime
Posttranslational modification of the carboxy-terminal region of the beta subunit of human chorionic gonadotropin.
Biochemistry 1984;23(22):5330-7.
1984: Steven Birken; G Agosto; B Lahiri; Robert E Canfield
Preparation and characterization of NH2-terminal fibrinogen B beta fragments from N-DSK of human fibrinogen.
Thrombosis and haemostasis 1984;51(1):16-21.
1984: S Amr; C Rosa; R Wehmann; Steven Birken; B Nisula
Unusual molecular forms of hCG in gestational trophoblastic neoplasia.
Annales d'endocrinologie 1984;45(4-5):321-6.
1983: J H Sobel; P H Ehrlich; Steven Birken; A J Saffran; Robert E Canfield
Monoclonal antibody to the region of fibronectin involved in cross-linking to human fibrin.
Biochemistry 1983;22(18):4175-83.
1983: S Amr; R E Wehmann; Steven Birken; Robert E Canfield; B C Nisula
Characterization of a carboxyterminal peptide fragment of the human choriogonadotropin beta-subunit excreted in the urine of a woman with choriocarcinoma.
The Journal of clinical investigation 1983;71(2):329-39.
1983: Joyce W Lustbader; J P Arcoleo; Steven Birken; J Greer
Hemoglobin-binding site on haptoglobin probed by selective proteolysis.
The Journal of biological chemistry 1983;258(2):1227-34.
1982: Steven Birken; Robert E Canfield; G Agosto; J Lewis
Preparation and characterization of an improved beta-COOH-terminal immunogen for generation of specific and sensitive antisera to human chorionic gonadotropin.
Endocrinology 1982;110(5):1555-63.
1982: G S Taliadouros; S Amr; J P Louvet; Steven Birken; R E Canfield; B C Nisula
Biological and immunological characterization of crude commercial human choriogonadotropin.
The Journal of clinical endocrinology and metabolism 1982;54(5):1002-9.
1981: R E Wehmann; S Mitchell Harman; Steven Birken; R E Canfield; B C Nisula
Convenient radioimmunoassay for urinary human choriogonadotropin without interference by urinary human lutropin.
Clinical chemistry 1981;27(12):1997-2001.
1981: H R Masure; W L Jaffee; M A Sickel; Steven Birken; Robert E Canfield; J L Vaitukaitis
Characterization of a small molecular size urinary immunoreactive human chorionic gonadotropin (hCG)-like substance produced by normal placenta and by hCG-secreting neoplasms.
The Journal of clinical endocrinology and metabolism 1981;53(5):1014-20.
1981: R E Wehmann; A R Ayala; Steven Birken; R E Canfield; B C Nisula
Improved monitoring of gestational trophoblastic neoplasia using a highly sensitive assay for urinary human chorionic gonadotropin.
American journal of obstetrics and gynecology 1981;140(7):753-7.
1981: B Lahiri; J A Koehn; Robert E Canfield; Steven Birken; J Lewis
Development of an immunoassay for the COOH-terminal region of the gamma chains of human fibrin.
Thrombosis research 1981;23(1-2):103-12.
1981: T Isobe; K Takatsuki; F W Tishendorf; Steven Birken; E F Osserman
Plasma cell myeloma, hyperviscosity and amyloidosis associated with a serum IgG3 lambda and urinary excretion of two fragments related to the variable portion of lambda light chains.
Clinical immunology and immunopathology 1981;19(1):55-66.
1981: Steven Birken; J Fetherston; R Canfield; I Boime
The amino acid sequences of the prepeptides contained in the alpha and beta subunits of human choriogonadotropin.
The Journal of biological chemistry 1981;256(4):1816-23.
1980: Steven Birken; Robert E Canfield; R Lauer; G Agosto; M Gabel
Immunochemical determinants unique to human chorionic gonadotropin: importance of sialic acid for antisera generated to the human chorionic gonadotropin beta-subunit COOH-terminal peptide.
Endocrinology 1980;106(6):1659-64.