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Yongqun He

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TOP 3
Rebecca Racz; Zuoshuang Xiang; Monica Chung; Yongqun He
Systematic annotation and analysis of "virmugens"-virulence factors whose mutants can be used as live attenuated vaccines.
Yongqun He; Zuoshuang Xiang
Databases and in silico tools for vaccine design.
Zuoshuang Xiang; Yongqun He
Genome-wide prediction of vaccine targets for human herpes simplex viruses using Vaxign reverse vaccinology.

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All Publications

2013: Rebecca Racz; Zuoshuang Xiang; Monica Chung; Yongqun He
Systematic annotation and analysis of "virmugens"-virulence factors whose mutants can be used as live attenuated vaccines.
Vaccine 2013;31(5):797-805.
2013: Yongqun He; Zuoshuang Xiang
Databases and in silico tools for vaccine design.
Methods in molecular biology (Clifton, N.J.) 2013;993():115-27.
2013: Zuoshuang Xiang; Yongqun He
Genome-wide prediction of vaccine targets for human herpes simplex viruses using Vaxign reverse vaccinology.
BMC bioinformatics 2013;14 Suppl 4():S2.
2013: Yongqun He; Vladimir Brusic; Zhiwei Cao; Anne S De Groot; Christian Schönbach; Nikolai Petrovsky
Computational vaccinology and the ICoVax 2012 workshop.
BMC bioinformatics 2013;14 Suppl 4():I1.
2012: Wenxiao Liu; Qixing Ou; Buyun Cui; Yongqun He; Zhigang Jing; Qingmin Wu
Complete genome sequence of Brucella melitensis biovar 3 strain NI, isolated from an aborted bovine fetus.
Journal of bacteriology 2012;194(22):6321.
2012: Cui Tao; Hannah Yang; Yongqun He; Gregory A Poland; Christopher G Chute
Ontology-based time information representation of vaccine adverse events in VAERS for temporal analysis.
Journal of biomedical semantics 2012;3(1):13.
2012: Junguk Hur; Arzucan Ozgür; Zuoshuang Xiang; Yongqun He
Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining.
Journal of biomedical semantics 2012;3(1):18.
2012: Yu Lin; Yongqun He
Ontology representation and analysis of vaccine formulation and administration and their effects on vaccine immune responses.
Journal of biomedical semantics 2012;3(1):17.
2012: Yongqun He; Cui Tao; Luca Toldo; Gully Burns; Darrell R. Abernethy
A 2012 Workshop: Vaccine and Drug Ontology in the Study of Mechanism and Effect (VDOSME 2012).
Journal of biomedical semantics 2012;3(1):12.
2012: Sirarat Sarntivijai; Kerby Shedden; Zuoshuang Xiang; Brian D Athey; Howard Markel; Gilbert S Omenn; Yongqun He
Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines.
PloS one 2012;7(11):e49941.
2012: Xinna Li; Yongqun He
Caspase-2-dependent dendritic cell death, maturation, and priming of T cells in response to Brucella abortus infection.
PloS one 2012;7(8):e43512.
2012: Menachem Banai; Yongqun He
Systems biology and bioinformatics help decipher Brucella antigens involved in clinical manifestation of the disease.
Frontiers in cellular and infection microbiology 2012;2():34.
2012: Yongqun He
Analyses of Brucella pathogenesis, host immunity, and vaccine targets using systems biology and bioinformatics.
Frontiers in cellular and infection microbiology 2012;2():2.
2012: Samantha Sayers; Guerlain Ulysse; Zuoshuang Xiang; Yongqun He
Vaxjo: a web-based vaccine adjuvant database and its application for analysis of vaccine adjuvants and their uses in vaccine development.
Journal of biomedicine & biotechnology 2012;2012():831486.
2011: Fang Chen; Xicheng Ding; Ying Ding; Zuoshuang Xiang; Xinna Li; Debashis Ghosh; Gerhardt G Schurig; Nammalwar Sriranganathan; Stephen M Boyle; Yongqun He
Proinflammatory caspase-2-mediated macrophage cell death induced by a rough attenuated Brucella suis strain.
Infection and immunity 2011;79(6):2460-9.
2011: Jianguo Zhu; Fang Chen; George W Jourdian; Kimberly P Ku; Charles B Larson; Kimberly Quandt; Megan Ann Ramaker; Gerhardt G Schurig; Ramesh Vemulapalli; Jered M Wendte; Yongqun He
Characterization of recombinant B. abortus strain RB51SOD toward understanding the uncorrelated innate and adaptive immune responses induced by RB51SOD compared to its parent vaccine strain RB51.
Frontiers in cellular and infection microbiology 2011;1():10.
2011: Yu Lin; Zuoshuang Xiang; Yongqun He
Brucellosis Ontology (IDOBRU) as an extension of the Infectious Disease Ontology.
Journal of biomedical semantics 2011;2(1):9.
2011: Junguk Hur; Zuoshuang Xiang; Eva L Feldman; Yongqun He
Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network.
BMC immunology 2011;12():49.
2011: Arzucan Ozgür; Zuoshuang Xiang; Dragomir R Radev; Yongqun He
Mining of vaccine-associated IFN-γ gene interaction networks using the Vaccine Ontology.
Journal of biomedical semantics 2011;2 Suppl 2():S8.
2011: Patrick D Vigil; Ann E Stapleton; James R Johnson; Thomas Hooton; Andrew P Hodges; Yongqun He; harry mobley
Presence of putative repeat-in-toxin gene tosA in Escherichia coli predicts successful colonization of the urinary tract.
mBio 2011;2(3):e00066-11.
2011: James A Shayman; Robert Kelly; Jessica Kollmeyer; Yongqun He; Akira Abe
Group XV phospholipase A₂, a lysosomal phospholipase A₂.
Progress in lipid research 2011;50(1):1-13.
2011: Brian Yang; Samantha Sayers; Zuoshuang Xiang; Yongqun He
Protegen: a web-based protective antigen database and analysis system.
Nucleic acids research 2011;39(Database issue):D1073-8.
2010: Andrew P Hodges; Peter Woolf; Yongqun He
BN+1 Bayesian network expansion for identifying molecular pathway elements.
Communicative & integrative biology 2010;3(6):549-54.
2010: Brian R Sloat; Michael A Sandoval; Andrew M Hau; Yongqun He; Zhengrong Cui
Strong antibody responses induced by protein antigens conjugated onto the surface of lecithin-based nanoparticles.
Journal of controlled release : official journal of the Controlled Release Society 2010;141(1):93-100.
2010: Yongqun He; Anne S De Groot; Rino Rappuoli; Robert T Chen
Vaccine informatics.
Journal of biomedicine & biotechnology 2010;2010():765762.
2010: Yongqun He; Rino Rappuoli; Anne S De Groot; Robert T Chen
Emerging vaccine informatics.
Journal of biomedicine & biotechnology 2010;2010():218590.
2010: Yongqun He; Zuoshuang Xiang
Bioinformatics analysis of Brucella vaccines and vaccine targets using VIOLIN.
Immunome research 2010;6 Suppl 1():S5.
2010: Yongqun He; Zuoshuang Xiang; harry mobley
Vaxign: the first web-based vaccine design program for reverse vaccinology and applications for vaccine development.
Journal of biomedicine & biotechnology 2010;2010():297505.
2010: Ryan R Brinkman; Mélanie Courtot; Dirk Derom; Jennifer M Fostel; Yongqun He; Phillip Lord; James Malone; Helen Parkinson; Bjoern Peters; Philippe Rocca-Serra; Alan Ruttenberg; Susanna-Assunta Sansone; Larisa N Soldatova; Christian J Stoeckert; Jessica Turner; Jie Zheng
Modeling biomedical experimental processes with OBI.
Journal of biomedical semantics 2010;1 Suppl 1():S7.
2010: Arzucan Ozgür; Zuoshuang Xiang; Dragomir R Radev; Yongqun He
Literature-based discovery of IFN-gamma and vaccine-mediated gene interaction networks.
Journal of biomedicine & biotechnology 2010;2010():426479.
2010: Zuoshuang Xiang; Mélanie Courtot; Ryan R Brinkman; Alan Ruttenberg; Yongqun He
OntoFox: web-based support for ontology reuse.
BMC research notes 2010;3():175.
2010: Lucy A McNamara; Yongqun He; Zhenhua Yang
Using epitope predictions to evaluate efficacy and population coverage of the Mtb72f vaccine for tuberculosis.
BMC immunology 2010;11():18.
2010: Andrew P Hodges; Dongjuan Dai; Zuoshuang Xiang; Peter Woolf; Chuanwu Xi; Yongqun He
Bayesian network expansion identifies new ROS and biofilm regulators.
PloS one 2010;5(3):e9513.
2009: Fang Chen; Yongqun He
Caspase-2 mediated apoptotic and necrotic murine macrophage cell death induced by rough Brucella abortus.
PloS one 2009;4(8):e6830.
2008: Zuoshuang Xiang; Thomas Todd; Kim P Ku; Bethany L Kovacic; Charles B Larson; Fang Chen; Andrew P Hodges; Yuying Tian; Elizabeth A Olenzek; Boyang Zhao; Lesley A Colby; Howard G Rush; Janet R Gilsdorf; George W Jourdian; Yongqun He
VIOLIN: vaccine investigation and online information network.
Nucleic acids research 2008;36(Database issue):D923-8.
2007: Zuoshuang Xiang; Rebecca M Minter; Xiaoming Bi; Peter J Woolf; Yongqun He
miniTUBA: medical inference by network integration of temporal data using Bayesian analysis.
Bioinformatics (Oxford, England) 2007;23(18):2423-32.
2007: Zuoshuang Xiang; Zhaohui S Qin; Yongqun He
CRCView: a web server for analyzing and visualizing microarray gene expression data using model-based clustering.
Bioinformatics (Oxford, England) 2007;23(14):1843-5.
2007: Yongqun He; Howard G Rush; Rachel S Liepman; Zuoshuang Xiang; Lesley A Colby
Pathobiology and management of laboratory rodents administered CDC category A agents.
Comparative medicine 2007;57(1):18-32.
2007: Zuoshuang Xiang; Yuying Tian; Yongqun He
PHIDIAS: a pathogen-host interaction data integration and analysis system.
Genome biology 2007;8(7):R150.
2006: Yongqun He; Sherry Reichow; Sheela Ramamoorthy; Xicheng Ding; Raju Lathigra; Johanna C Craig; Bruno Sobral; Gerhardt G Schurig; Nammalwar Sriranganathan; Stephen M Boyle
Brucella melitensis triggers time-dependent modulation of apoptosis and down-regulation of mitochondrion-associated gene expression in mouse macrophages.
Infection and immunity 2006;74(9):5035-46.
2006: Zuoshuang Xiang; Wenjie Zheng; Yongqun He
BBP: Brucella genome annotation with literature mining and curation.
BMC bioinformatics 2006;7():347.
2006: Vladyslava G Ratushna; David M Sturgill; Sheela Ramamoorthy; Sherry A Reichow; Yongqun He; Raju Lathigra; Nammalwar Sriranganathan; Shirley M Halling; Stephen M Boyle; Cynthia J Gibas
Molecular targets for rapid identification of Brucella spp.
BMC microbiology 2006;6():13.
2005: Yongqun He; Richard R Vines; Alice R Wattam; Georgiy V Abramochkin; Allan Dickerman; J Dana Eckart; Bruno Sobral
PIML: the Pathogen Information Markup Language.
Bioinformatics (Oxford, England) 2005;21(1):116-21.
2002: Ramesh Vemulapalli; Yongqun He; Nammalwar Sriranganathan; Stephen M Boyle; Gerhardt G Schurig
Brucella abortus RB51: enhancing vaccine efficacy and developing multivalent vaccines.
Veterinary microbiology 2002;90(1-4):521-32.
2002: Yongqun He; Ramesh Vemulapalli; Gerhardt G Schurig
Recombinant Ochrobactrum anthropi expressing Brucella abortus Cu,Zn superoxide dismutase protects mice against B. abortus infection only after switching of immune responses to Th1 type.
Infection and immunity 2002;70(5):2535-43.
2001: Yongqun He; Ramesh Vemulapalli; Ahmet Zeytun; Gerhardt G Schurig
Induction of specific cytotoxic lymphocytes in mice vaccinated with Brucella abortus RB51.
Infection and immunity 2001;69(9):5502-8.
2000: Ramesh Vemulapalli; Yongqun He; L S Buccolo; Stephen M Boyle; Nammalwar Sriranganathan; Gerhardt G Schurig
Complementation of Brucella abortus RB51 with a functional wboA gene results in O-antigen synthesis and enhanced vaccine efficacy but no change in rough phenotype and attenuation.
Infection and immunity 2000;68(7):3927-32.
2000: Ramesh Vemulapalli; Yongqun He; Stephen M Boyle; Nammalwar Sriranganathan; Gerhardt G Schurig
Brucella abortus strain RB51 as a vector for heterologous protein expression and induction of specific Th1 type immune responses.
Infection and immunity 2000;68(6):3290-6.
2000: Ramesh Vemulapalli; Yongqun He; Silvio L Cravero; Nammalwar Sriranganathan; Stephen M Boyle; Gerhardt G Schurig
Overexpression of protective antigen as a novel approach to enhance vaccine efficacy of Brucella abortus strain RB51.
Infection and immunity 2000;68(6):3286-9.