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Thiruma Arumugam

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Silvia Manzanero; Tomislav Santro; Thiruma V Arumugam
Neuronal oxidative stress in acute ischemic stroke: sources and contribution to cell injury.
Sung-Chun Tang; Yu-Chi Wang; Wei-Shiung Yang; Thiruma V Arumugam; Hung-Yi Chiou; Yu-Hsuan Hsieh; Chaur-Jong Hu; Yi-Shuian Huang; Yu-I Li; Hsiao-Ching Lin; Silvia Manzanero; Mark P Mattson; Simon Phipps; Jiann-Shing Jeng
Functional role of soluble receptor for advanced glycation end products in stroke.
John Thundyil; Alexander Widiapradja; Masahide Asano; Prasad Chunduri; Mark G Coulthard; Tanya R Cully; Dong-Gyu Jo; Bradley S Launikonis; Ker-Zhing Lok; Silvia Manzanero; Chie Naruse; Dale Pavlovski; Christopher G Sobey; Thiruma V Arumugam
Evidence that the EphA2 receptor exacerbates ischemic brain injury.

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All Publications

2013: Silvia Manzanero; Tomislav Santro; Thiruma V Arumugam
Neuronal oxidative stress in acute ischemic stroke: sources and contribution to cell injury.
Neurochemistry international 2013;62(5):712-8.
2013: Sung-Chun Tang; Yu-Chi Wang; Wei-Shiung Yang; Thiruma V Arumugam; Hung-Yi Chiou; Yu-Hsuan Hsieh; Chaur-Jong Hu; Yi-Shuian Huang; Yu-I Li; Hsiao-Ching Lin; Silvia Manzanero; Mark P Mattson; Simon Phipps; Jiann-Shing Jeng
Functional role of soluble receptor for advanced glycation end products in stroke.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(3):585-94.
2013: John Thundyil; Alexander Widiapradja; Masahide Asano; Prasad Chunduri; Mark G Coulthard; Tanya R Cully; Dong-Gyu Jo; Bradley S Launikonis; Ker-Zhing Lok; Silvia Manzanero; Chie Naruse; Dale Pavlovski; Christopher G Sobey; Thiruma V Arumugam
Evidence that the EphA2 receptor exacerbates ischemic brain injury.
PloS one 2013;8(1):e53528.
2013: Brad R S Broughton; Grant R Drummond; Chantelle V Gardiner-Mann; Elizabeth Guida; Seyoung Lee; Alyson A Miller; Thiruma V Arumugam; Vanessa H Brait; Sung-Chun Tang; Christopher G Sobey
Stroke increases g protein-coupled estrogen receptor expression in the brain of male but not female mice.
Neuro-Signals 2013;21(3-4):229-39.
2012: Mark G Coulthard; Martin Lackmann; Michael Morgan; Stephen M Taylor; Trent M Woodruff; Thiruma V Arumugam; Todd C Carpenter; Andrew W Boyd
Eph/Ephrin signaling in injury and inflammation.
The American journal of pathology 2012;181(5):1493-503.
2012: Mathias Gelderblom; Christian Gerloff; Markus Glatzel; Christoph Hölscher; Thomas Korn; Frank Leypoldt; Thiruma V Arumugam; Priyadharshini Arunachalam; Christian Bernreuther; Manuel A Friese; Ellen Orthey; Immo Prinz; Olga Simova; Karin Steinbach; Vivien Thom; Eva Tolosa; Joachim Velden; Anna Weymar; Tim Magnus
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Blood 2012;120(18):3793-802.
2012: Hyun Ah Kim; Alyson A Miller; Thanh G Phan; Thiruma V Arumugam; Grant R Drummond; Velandai K Srikanth; Amanda G Thrift; Christopher G Sobey
Vascular cognitive impairment and Alzheimer's disease: role of cerebral hypoperfusion and oxidative stress.
Naunyn-Schmiedeberg's archives of pharmacology 2012;385(10):953-9.
2012: A-Ryeong Gwon; Dong-Hoon Hyun; Thiruma V Arumugam; Sang-Ha Baik; Michel Bernier; Sic L Chan; Aiwu Cheng; Yuri Choi; Charles E Dann; Saerom Kim; Seol-Hee Kim; Yong-Kook Kwon; Jaewon Lee; William R Markesbery; Mark P Mattson; Jong-Sung Park; Sung-Chun Tang; Sunghee Yang; Young-Kwang Yun; Dong-Gyu Jo
Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.
Aging cell 2012;11(4):559-68.
2012: Mathias Gelderblom; Christian Gerloff; Jan Lewerenz; Frank Leypoldt; Peter Ludewig; Pamela Maher; Denise Orozco; John Thundyil; Eva Tolosa; Thiruma V Arumugam; Gabriel Birkenmayer; Tim Magnus
The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(5):835-43.
2012: Vanessa H Brait; Grant R Drummond; Thiruma V Arumugam; Christopher G Sobey
Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(4):598-611.
2012: John Thundyil; David P Fairlie; Mathias Gelderblom; Yu-Hsuan Hsieh; Tim Magnus; Dale Pavlovski; Thiruma V Arumugam
C5a receptor (CD88) inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model.
Neuromolecular medicine 2012;14(1):30-9.
2012: Brad R S Broughton; Grant R Drummond; Rebecca Lim; Thiruma V Arumugam; Euan M Wallace; Christopher G Sobey
Post-stroke inflammation and the potential efficacy of novel stem cell therapies: focus on amnion epithelial cells.
Frontiers in cellular neuroscience 2012;6():66.
2012: Vanessa H Brait; Brad R S Broughton; Alicia Corlett; Grant R Drummond; Hyun Ah Kim; Katherine R Martin; Melanie A Pritchard; Thiruma V Arumugam; John Thundyil; Christopher G Sobey
Over-expression of DSCR1 protects against post-ischemic neuronal injury.
PloS one 2012;7(10):e47841.
2012: Quynh N Dinh; Grant R Drummond; Christopher G Sobey; Morag J Young; Thiruma V Arumugam; Sophocles Chrissobolis
Aldosterone and the mineralocorticoid receptor in the cerebral circulation and stroke.
Experimental & translational stroke medicine 2012;4(1):21.
2012: Eitan Okun; Mario A Pita; Nicholas Roberts; Sarah M Rothman; Ravit Saada-Madar; Alexis M Stranahan; Thiruma V Arumugam; Boaz Barak; Kamilah Castro; Kathleen J Griffioen; Mohamed R Mughal; Mark P Mattson
Evidence for a developmental role for TLR4 in learning and memory.
PloS one 2012;7(10):e47522.
2012: Seyoung Lee; Christopher G Sobey; Robert E Widdop; Hyun Ah Kim; Thiruma V Arumugam; Vanessa H Brait; Grant R Drummond; Megan A Evans; Emma S Jones
Neuroprotective effect of an angiotensin receptor type 2 agonist following cerebral ischemia in vitro and in vivo.
Experimental & translational stroke medicine 2012;4(1):16.
2011: Yu-Hsuan Hsieh; Silvia Manzanero; Kieran McCartney; Tyson A Moore; John Thundyil; Mathias Gelderblom; Thiruma V Arumugam
Intestinal ischemia-reperfusion injury leads to inflammatory changes in the brain.
Shock (Augusta, Ga.) 2011;36(4):424-30.
2011: Zelan Wei; Thiruma V Arumugam; Srinivasulu Chigurupati; Dong-Gyu Jo; He Li; Sic L Chan
Notch activation enhances the microglia-mediated inflammatory response associated with focal cerebral ischemia.
Stroke; a journal of cerebral circulation 2011;42(9):2589-94.
2011: Thiruma V Arumugam; Sic L Chan; Yi-Lin Cheng; Yuri Choi; Yun-Hyung Choi; Mathias Gelderblom; Vardan T Karamyan; Tim Magnus; Jong-Sung Park; Christopher G Sobey; Sung-Chun Tang; John Thundyil; Dong Kwon Yang; Sunghee Yang; Young-Kwang Yun; Dong-Gyu Jo
Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.
Molecular pharmacology 2011;80(1):23-31.
2011: Sunil K Panchal; Hemant Poudyal; Thiruma V Arumugam; Lindsay Brown
Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats.
The Journal of nutrition 2011;141(6):1062-9.
2011: Mohamed R Mughal; Akanksha Baharani; Srinivasulu Chigurupati; Tae Gen Son; Edmund Chen; Peter Yang; Eitan Okun; Thiruma V Arumugam; Sic L Chan; Mark P Mattson
Electroconvulsive shock ameliorates disease processes and extends survival in huntingtin mutant mice.
Human molecular genetics 2011;20(4):659-69.
2011: Silvia Manzanero; Mathias Gelderblom; Tim Magnus; Thiruma V Arumugam
Calorie restriction and stroke.
Experimental & translational stroke medicine 2011;3():8.
2011: Trent Woodruff; John Thundyil; Sung-Chun Tang; Christopher G Sobey; Stephen M Taylor; Thiruma V Arumugam
Pathophysiology, treatment, and animal and cellular models of human ischemic stroke.
Molecular neurodegeneration 2011;6(1):11.
2011: Alexis M Stranahan; Thiruma V Arumugam; Mark P Mattson
Lowering corticosterone levels reinstates hippocampal brain-derived neurotropic factor and Trkb expression without influencing deficits in hypothalamic brain-derived neurotropic factor expression in leptin receptor-deficient mice.
Neuroendocrinology 2011;93(1):58-64.
2010: Mamoon Rashid; Thiruma V Arumugam; Vardan T Karamyan
Association of the novel non-AT1, non-AT2 angiotensin binding site with neuronal cell death.
The Journal of pharmacology and experimental therapeutics 2010;335(3):754-61.
2010: Eitan Okun; Kathleen J Griffioen; Tae Gen Son; Jong-Hwan Lee; Nicholas J Roberts; Mohamed R Mughal; Emmette Hutchison; Aiwu Cheng; Thiruma V Arumugam; Justin D Lathia; Henriette van Praag; Mark P Mattson
TLR2 activation inhibits embryonic neural progenitor cell proliferation.
Journal of neurochemistry 2010;114(2):462-74.
2010: Alexis M Stranahan; Thiruma V Arumugam; Kim Lee; Mark P Mattson
Mineralocorticoid receptor activation restores medial perforant path LTP in diabetic rats.
Synapse (New York, N.Y.) 2010;64(7):528-32.
2010: Eitan Okun; Mark P Mattson; Thiruma V Arumugam
Involvement of Fc receptors in disorders of the central nervous system.
Neuromolecular medicine 2010;12(2):164-78.
2010: Tae Gen Son; Simonetta Camandola; Thiruma V Arumugam; Roy G Cutler; Richard S Telljohann; Mohamed R Mughal; Tyson A Moore; Weiming Luo; Qian-Sheng Yu; Delinda A Johnson; Jeffrey A Johnson; Nigel H Greig; Mark P Mattson
Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia.
Journal of neurochemistry 2010;112(5):1316-26.
2010: Yun-Hyung Choi; A-Ryeong Gwon; Hye-Young Jeong; Jong-Sung Park; Sang-Ha Baik; Thiruma V Arumugam; Dong-Gyu Jo
Contribution of gamma-secretase to calcium-mediated cell death.
Neuroscience letters 2010;469(3):425-8.
2010: John Thundyil; Sung-Chun Tang; Eitan Okun; Kausik Shah; Vardan T Karamyan; Yu-I Li; Trent Woodruff; Stephen M Taylor; Dong-Gyu Jo; Mark P Mattson; Thiruma V Arumugam
Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death.
Experimental & translational stroke medicine 2010;2(1):15.
2010: Srinivasulu Chigurupati; Mohamed R Mughal; Sic L Chan; Thiruma V Arumugam; Akanksha Baharani; Sung-Chun Tang; Qian-Sheng Yu; Harold W Holloway; Ross Wheeler; Suresh Poosala; Nigel H Greig; Mark P Mattson
A synthetic uric acid analog accelerates cutaneous wound healing in mice.
PloS one 2010;5(4):e10044.
2010: Thiruma V Arumugam; Terry M Phillips; Aiwu Cheng; Christopher H Morrell; Mark P Mattson; Ruiqian Wan
Age and energy intake interact to modify cell stress pathways and stroke outcome.
Annals of neurology 2010;67(1):41-52.
2010: Justin D Lathia; Srinivasulu Chigurupati; John Thundyil; Pradeep K Selvaraj; Mohamed R Mughal; Trent Woodruff; Sic L Chan; Vardan T Karamyan; Mark P Mattson; Thiruma V Arumugam
Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke.
Experimental neurology 2010;221(1):107-14.
2009: Ha-Na Woo; Jong-Sung Park; A-Ryeong Gwon; Thiruma V Arumugam; Dong-Gyu Jo
Alzheimer's disease and Notch signaling.
Biochemical and biophysical research communications 2009;390(4):1093-7.
2009: Srinivasulu Chigurupati; Zelan Wei; Cherine Belal; Myriam Vandermey; George A Kyriazis; Thiruma V Arumugam; Sic L Chan
The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of CCAAT enhancer-binding protein homologous protein in a neurotoxin model of Parkinson disease.
The Journal of biological chemistry 2009;284(27):18323-33.
2009: Thiruma V Arumugam; Eitan Okun; Sung-Chun Tang; John Thundyil; Stephen M Taylor; Trent Woodruff
Toll-like receptors in ischemia-reperfusion injury.
Shock (Augusta, Ga.) 2009;32(1):4-16.
2009: Mathias Gelderblom; Frank Leypoldt; Karin Steinbach; Doerthe Behrens; Chi-Un Choe; Dominic A Siler; Thiruma V Arumugam; Ellen Orthey; Christian Gerloff; Eva Tolosa; Tim Magnus
Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.
Stroke; a journal of cerebral circulation 2009;40(5):1849-57.
2009: Lloyd F Alfonso; Kalkunte S Srivenugopal; Thiruma V Arumugam; Thomas J Abbruscato; Jon A Weidanz; G Jayarama Bhat
Aspirin inhibits camptothecin-induced p21CIP1 levels and potentiates apoptosis in human breast cancer cells.
International journal of oncology 2009;34(3):597-608.
2009: Eitan Okun; Kathleen J Griffioen; Justin D Lathia; Sung-Chun Tang; Mark P Mattson; Thiruma V Arumugam
Toll-like receptors in neurodegeneration.
Brain research reviews 2009;59(2):278-92.
2009: Thiruma V Arumugam; Trent Woodruff; Justin D Lathia; P K Selvaraj; Mark P Mattson; S M Taylor
Neuroprotection in stroke by complement inhibition and immunoglobulin therapy.
Neuroscience 2009;158(3):1074-89.
2008: Srinivasulu Chigurupati; Tae Gen Son; Dong-Hoon Hyun; Justin D Lathia; Mohamed R Mughal; Jason Savell; Shuan C Li; G P C Nagaraju; Sic L Chan; Thiruma V Arumugam; Mark P Mattson
Lifelong running reduces oxidative stress and degenerative changes in the testes of mice.
The Journal of endocrinology 2008;199(2):333-41.
2008: Sung-Chun Tang; Justin D Lathia; Pradeep K Selvaraj; Dong-Gyu Jo; Mohamed R Mughal; Aiwu Cheng; Dominic A Siler; William R Markesbery; Thiruma V Arumugam; Mark P Mattson
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal.
Experimental neurology 2008;213(1):114-21.
2008: Alexis M Stranahan; Thiruma V Arumugam; Roy G Cutler; Kim Lee; Josephine M Egan; Mark P Mattson
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons.
Nature neuroscience 2008;11(3):309-17.
2008: Thiruma V Arumugam; Pradeep K Selvaraj; Trent Woodruff; Mark P Mattson
Targeting ischemic brain injury with intravenous immunoglobulin.
Expert opinion on therapeutic targets 2008;12(1):19-29.
2007: Thiruma V Arumugam; Sung-Chun Tang; Justin D Lathia; Aiwu Cheng; Mohamed R Mughal; Srinivasulu Chigurupati; Tim Magnus; Sic L Chan; Dong-Gyu Jo; Xin Ouyang; David P Fairlie; Daniel N Granger; Alexander O Vortmeyer; Milan Basta; Mark P Mattson
Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):14104-9.
2007: Sung-Chun Tang; Thiruma V Arumugam; Xiangru Xu; Aiwu Cheng; Mohamed R Mughal; Dong-Gyu Jo; Justin D Lathia; Dominic A Siler; Srinivasulu Chigurupati; Xin Ouyang; Tim Magnus; Simonetta Camandola; Mark P Mattson
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13798-803.
2007: Eitan Okun; Thiruma V Arumugam; Sung-Chun Tang; Marc Gleichmann; Michael Albeck; Benjamin Sredni; Mark P Mattson
The organotellurium compound ammonium trichloro(dioxoethylene-0,0') tellurate enhances neuronal survival and improves functional outcome in an ischemic stroke model in mice.
Journal of neurochemistry 2007;102(4):1232-41.
2007: Tim Magnus; Turhan Coksaygan; Thomas Korn; Haipeng Xue; Thiruma V Arumugam; Mohamed R Mughal; D Mark Eckley; Sung-Chun Tang; Louis J DeTolla; Mahendra S Rao; Riccardo Cassiani Ingoni; Mark P Mattson
Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes.
Journal of neuroscience research 2007;85(10):2126-37.
2007: Sung-Chun Tang; Thiruma V Arumugam; Roy G Cutler; Dong-Gyu Jo; Tim Magnus; Sic L Chan; Mohamed R Mughal; Richard S Telljohann; Matthew Nassar; Xin Ouyang; Andrea Calderan; Paolo Ruzza; Andrea Guiotto; Mark P Mattson
Neuroprotective actions of a histidine analogue in models of ischemic stroke.
Journal of neurochemistry 2007;101(3):729-36.
2007: Aiwu Cheng; Thiruma V Arumugam; Dong Liu; Rina Khatri; Khadija Mustafa; Seung Kwak; Huai-Ping Ling; Cathleen Gonzales; Ouyang Xin; Dong-Gyu Jo; Zhihong Guo; RJ Mark; Mark P Mattson
Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(7):1519-28.
2007: Srinivasulu Chigurupati; Thiruma V Arumugam; Tae Gen Son; Justin D Lathia; Shafaq Jameel; Mohamed R Mughal; Sung-Chun Tang; Dong-Gyu Jo; Simonetta Camandola; Marialuisa Giunta; Irina Rakova; Nazli McDonnell; Lucio Miele; Mark P Mattson; Suresh Poosala
Involvement of notch signaling in wound healing.
PloS one 2007;2(11):e1167.
2007: Frank Haberman; Sung-Chun Tang; Thiruma V Arumugam; Dong-Hoon Hyun; Qian-Sheng Yu; Roy G Cutler; Zhihong Guo; Harold W Holloway; Nigel H Greig; Mark P Mattson
Soluble neuroprotective antioxidant uric acid analogs ameliorate ischemic brain injury in mice.
Neuromolecular medicine 2007;9(4):315-23.
2006: Thiruma V Arumugam; Tim Magnus; Trent Woodruff; Lavinia M Proctor; Ian A Shiels; Stephen M Taylor
Complement mediators in ischemia-reperfusion injury.
Clinica chimica acta; international journal of clinical chemistry 2006;374(1-2):33-45.
2006: Thiruma V Arumugam; Sic L Chan; Dong-Gyu Jo; Gokhan Yilmaz; Sung-Chun Tang; Aiwu Cheng; Marc Gleichmann; Eitan Okun; Vishwa Deep Dixit; Srinivasulu Chigurupati; Mohamed R Mughal; Xin Ouyang; Lucio Miele; Tim Magnus; Suresh Poosala; D Neil Granger; Mark P Mattson
Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke.
Nature medicine 2006;12(6):621-3.
2006: Gokhan Yilmaz; Thiruma V Arumugam; Karen Y Stokes; D Neil Granger
Role of T lymphocytes and interferon-gamma in ischemic stroke.
Circulation 2006;113(17):2105-12.
2006: Thiruma V Arumugam; Marc Gleichmann; Sung-Chun Tang; Mark P Mattson
Hormesis/preconditioning mechanisms, the nervous system and aging.
Ageing research reviews 2006;5(2):165-78.
2005: Trent Woodruff; Thiruma V Arumugam; Ian A Shiels; Michelle L Newman; Paul A Ross; Robert C Reid; David P Fairlie; Stephen M Taylor
A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis.
International immunopharmacology 2005;5(5):883-92.
2005: Mami Ishikawa; Thorsten Vowinkel; Karen Y Stokes; Thiruma V Arumugam; Gokhan Yilmaz; Anil Nanda; D Neil Granger
CD40/CD40 ligand signaling in mouse cerebral microvasculature after focal ischemia/reperfusion.
Circulation 2005;111(13):1690-6.
2005: Thiruma V Arumugam; D Neil Granger; Mark P Mattson
Stroke and T-cells.
Neuromolecular medicine 2005;7(3):229-42.
2004: Thiruma V Arumugam; James W Salter; John H Chidlow; Christie M Ballantyne; Christopher Kevil; D Neil Granger
Contributions of LFA-1 and Mac-1 to brain injury and microvascular dysfunction induced by transient middle cerebral artery occlusion.
American journal of physiology. Heart and circulatory physiology 2004;287(6):H2555-60.
2004: Mami Ishikawa; Dianne Cooper; Thiruma V Arumugam; John Zhang; Anil Nanda; D Neil Granger
Platelet-leukocyte-endothelial cell interactions after middle cerebral artery occlusion and reperfusion.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(8):907-15.
2004: Lavinia M Proctor; Thiruma V Arumugam; Ian A Shiels; Robert C Reid; David P Fairlie; Stephen M Taylor
Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury.
British journal of pharmacology 2004;142(4):756-64.
2004: Thiruma V Arumugam; Trent Woodruff; Shelli Z Stocks; Lavinia M Proctor; Sandra Pollitt; Ian A Shiels; Robert C Reid; David P Fairlie; Stephen M Taylor
Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats.
Journal of hepatology 2004;40(6):934-41.
2004: Thiruma V Arumugam; Ian A Shiels; Trent Woodruff; D Neil Granger; Stephen M Taylor
The role of the complement system in ischemia-reperfusion injury.
Shock (Augusta, Ga.) 2004;21(5):401-9.
2004: Trent Woodruff; Thiruma V Arumugam; Ian A Shiels; Robert C Reid; David P Fairlie; Stephen M Taylor
Protective effects of a potent C5a receptor antagonist on experimental acute limb ischemia-reperfusion in rats.
The Journal of surgical research 2004;116(1):81-90.
2003: Trent Woodruff; Thiruma V Arumugam; Ian A Shiels; Robert C Reid; David P Fairlie; Stephen M Taylor
A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5514-20.
2003: Thiruma V Arumugam; Naomi Arnold; Lavinia M Proctor; Michelle Newman; Robert C Reid; Karl A Hansford; David P Fairlie; Ian A Shiels; Stephen M Taylor
Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist.
British journal of pharmacology 2003;140(1):71-80.
2003: Thiruma V Arumugam; Ian A Shiels; Anna J Strachan; Giovanni Abbenante; David P Fairlie; Stephen M Taylor
A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats.
Kidney international 2003;63(1):134-42.
2002: Thiruma V Arumugam; Ian A Shiels; Solomon B Margolin; Stephen M Taylor; Lindsay Brown
Pirfenidone attenuates ischaemia-reperfusion injury in the rat small intestine.
Clinical and experimental pharmacology & physiology 2002;29(11):996-1000.
2002: Thiruma V Arumugam; Ian A Shiels; Trent Woodruff; Robert C Reid; David P Fairlie; Stephen M Taylor
Protective effect of a new C5a receptor antagonist against ischemia-reperfusion injury in the rat small intestine.
The Journal of surgical research 2002;103(2):260-7.