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James Riley

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Dawn A Maier; Elena E Perez; Gabriela Plesa; James L Riley; S Kaye Spratt; Travis Wood; Zhaohui Zheng; Dale Ando; Gwendolyn K Binder-Scholl; Andrea L Brennan; Carmine Carpenito; Richard G Carroll; Julio Cotte; Philip Gregory; Michael C Holmes; Shuguang Jiang; Carl H June; Gary Lee; Bruce L Levine
Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5.
Max W Richardson; Chuka A Didigu; Robert W Doms; Julie Jadlowsky; James L Riley
Kruppel-like factor 2 modulates CCR5 expression and susceptibility to HIV-1 infection.
Sunil Martin; Bhaskar Saha; James L Riley
The battle over mTOR: an emerging theatre in host-pathogen immunity.

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All Publications

2013: Dawn A Maier; Elena E Perez; Gabriela Plesa; James L Riley; S Kaye Spratt; Travis Wood; Zhaohui Zheng; Dale Ando; Gwendolyn K Binder-Scholl; Andrea L Brennan; Carmine Carpenito; Richard G Carroll; Julio Cotte; Philip Gregory; Michael C Holmes; Shuguang Jiang; Carl H June; Gary Lee; Bruce L Levine
Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5.
Human gene therapy 2013;24(3):245-58.
2012: Max W Richardson; Chuka A Didigu; Robert W Doms; Julie Jadlowsky; James L Riley
Kruppel-like factor 2 modulates CCR5 expression and susceptibility to HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(8):3815-21.
2012: Sunil Martin; Bhaskar Saha; James L Riley
The battle over mTOR: an emerging theatre in host-pathogen immunity.
PLoS pathogens 2012;8(9):e1002894.
2012: Andrew J Rech; Adri Recio; James L Riley; Jennifer A Trosko; Carol K Tweed; Nicole A Aqui; Theresa Colligon; Angela DeMichele; Susan M Domchek; Kevin R Fox; Leah I Leinbach; Sunil Martin; Rosemarie Mick; Charles H Pletcher; Daniel J Powell; Robert H Vonderheide
CD25 blockade depletes and selectively reprograms regulatory T cells in concert with immunotherapy in cancer patients.
Science translational medicine 2012;4(134):134ra62.
2012: John Scholler; Ashley N Vogel; Michael Kalos; Bruce L Levine; Ronald T Mitsuyasu; Gabriela Plesa; James L Riley; Naomi E Aronson; Wendy B Bernstein; Gwendolyn Binder-Scholl; Troy L Brady; Frederic D Bushman; Steven G Deeks; Kristen M Hege; Wei-Ting Hwang; Carl H June
Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells.
Science translational medicine 2012;4(132):132ra53.
2012: Gabriela Plesa; Alan D Bennett; Bruce R Blazar; Jessie Gavarret; Bent K Jakobsen; Nathaniel Liddy; Andrew Medvec; Camila Robles-Oteiza; Annelise Vuidepot; Caleph B Wilson; Yangbing Zhao; Lingjie Zheng; James L Riley
TCR affinity and specificity requirements for human regulatory T-cell function.
Blood 2012;119(15):3420-30.
2011: Keli L Hippen; Carl H June; James L Riley; Bruce R Blazar
Clinical perspectives for regulatory T cells in transplantation tolerance.
Seminars in immunology 2011;23(6):462-8.
2011: Shoba Amarnath; Tania C Felizardo; Jason E Foley; Alice He; Carl H June; Veena Kapoor; Bruce L Levine; Courtney W Mangus; Paul R Massey; Jeffrey A Medin; James L Riley; James C M Wang; Fang Wei; Daniel H Fowler
The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.
Science translational medicine 2011;3(111):111ra120.
2011: Edmund K Moon; Daniel J Powell; Jarrod Predina; James L Riley; Jing Sun; Liang-Chuan S Wang; Carmine Carpenito; Carl H June; Veena Kapoor; Steven M Albelda
Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(14):4719-30.
2011: Keli L Hippen; Carl H June; S C Merkel; Jeffrey S Miller; C Nelson; James L Riley; D K Schirm; N C Tennis; John E Wagner; Bruce R Blazar
Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2011;11(6):1148-57.
2011: Keli L Hippen; Sarah C Merkel; Dawn K Schirm; Christine M Sieben; Darin Sumstad; Diane M Kadidlo; David H McKenna; Jonathan Bromberg; Bruce L Levine; James L Riley; Carl H June; Phillip Scheinberg; Daniel C Douek; Jeffrey S Miller; John E Wagner; Bruce R Blazar
Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity.
Science translational medicine 2011;3(83):83ra41.
2011: Craig B Wilen; Jianbin Wang; John C Tilton; Jeffrey C Miller; Kenneth A Kim; Edward J Rebar; Scott A Sherrill-Mix; Sean C Patro; Anthony J Secreto; Andrea P O Jordan; Gary Lee; Joshua Kahn; Pyone Aye; Bruce A Bunnell; Andrew A Lackner; James A Hoxie; Gwenn A Danet-Desnoyers; Frederic D Bushman; James L Riley; Philip D Gregory; Carl H June; Michael C Holmes; Robert W Doms
Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases.
PLoS pathogens 2011;7(4):e1002020.
2011: Qunrui Ye; James L Riley; Megan M Suhoski; George Coukos; Carl H June; Bruce L Levine; Maria Loisiou; Daniel J Powell
Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytes.
Journal of translational medicine 2011;9():131.
2011: Tatiana N Golovina; Tatiana Mikheeva; Todd Brusko; Bruce R Blazar; Jeffrey A Bluestone; James L Riley
Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells.
PloS one 2011;6(1):e15868.
2010: Chrystal M Paulos; Carmine Carpenito; Gabriela Plesa; Megan M Suhoski; Angel Varela-Rohena; Tatiana N Golovina; Richard G Carroll; James L Riley; Carl H June
The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells.
Science translational medicine 2010;2(55):55ra78.
2010: Rithun Mukherjee; Gabriela Plesa; Scott Sherrill-Mix; Max W Richardson; James L Riley; Frederic D Bushman
HIV sequence variation associated with env antisense adoptive T-cell therapy in the hNSG mouse model.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(4):803-11.
2010: Shoba Amarnath; Carliann M Costanzo; Jacopo Mariotti; Jessica L Ullman; William G Telford; Veena Kapoor; James L Riley; Bruce L Levine; Carl H June; Timothy Fong; Noel L Warner; Daniel H Fowler
Regulatory T cells and human myeloid dendritic cells promote tolerance via programmed death ligand-1.
PLoS biology 2010;8(2):e1000302.
2010: Joseph R Francica; Angel Varela-Rohena; Andrew Medvec; Gabriela Plesa; James L Riley; Paul Bates
Steric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein.
PLoS pathogens 2010;6(9):e1001098.
2009: Carl H June; Bruce R Blazar; James L Riley
Engineering lymphocyte subsets: tools, trials and tribulations.
Nature reviews. Immunology 2009;9(10):704-16.
2009: Michael C Milone; Jonathan D Fish; Carmine Carpenito; Richard G Carroll; Gwendolyn K Binder; David Teachey; Minu Samanta; Mehdi Lakhal; Brian Gloss; Gwenn Danet-Desnoyers; Dario Campana; James L Riley; Stephan A Grupp; Carl H June
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(8):1453-64.
2009: James L Riley; Carl H June; Bruce R Blazar
Human T regulatory cell therapy: take a billion or so and call me in the morning.
Immunity 2009;30(5):656-65.
2009: James L Riley
PD-1 signaling in primary T cells.
Immunological reviews 2009;229(1):114-25.
2009: Carmine Carpenito; Michael C Milone; Raffit Hassan; Jacqueline C Simonet; Mehdi Lakhal; Megan M Suhoski; Angel Varela-Rohena; Kathleen M Haines; Daniel F Heitjan; Steven M Albelda; Richard G Carroll; James L Riley; Ira Pastan; Carl H June
Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3360-5.
2008: Angel Varela-Rohena; Peter E Molloy; Steven M Dunn; Yi Li; Megan M Suhoski; Richard G Carroll; Anita Milicic; Tara Mahon; Deborah H Sutton; Bruno Laugel; Ruth Moysey; Brian J Cameron; Annelise Vuidepot; Marco A Purbhoo; david cole; Rodney E Phillips; Carl H June; Bent K Jakobsen; Andrew K Sewell; James L Riley
Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor.
Nature medicine 2008;14(12):1390-5.
2008: Max W Richardson; Richard G Carroll; Matthew Stremlau; Nikolay Korokhov; Laurent M Humeau; Guido Silvestri; Joseph Sodroski; James L Riley
Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha.
Journal of virology 2008;82(22):11117-28.
2008: Keli L Hippen; Paul Harker-Murray; Stephen B Porter; Sarah C Merkel; Aryel Londer; Dawn K Taylor; Megan Bina; Angela Panoskaltsis-Mortari; Pablo Rubinstein; Nico van Rooijen; Tatiana N Golovina; Megan M Suhoski; Jeffrey S Miller; John E Wagner; Carl H June; James L Riley; Bruce R Blazar
Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells.
Blood 2008;112(7):2847-57.
2008: Tatiana N Golovina; Tatiana Mikheeva; Megan M Suhoski; Nicole A Aqui; Victoria C Tai; Xiaochuan Shan; Ronghua Liu; R Robert Balcarcel; Nancy Fisher; Bruce L Levine; Richard G Carroll; Noel Warner; Bruce R Blazar; Carl H June; James L Riley
CD28 costimulation is essential for human T regulatory expansion and function.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(4):2855-68.
2008: Holli Kawadler; Mary A Gantz; James L Riley; Xiaolu Yang
The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation.
Molecular cell 2008;31(3):415-21.
2008: Elena E Perez; Jianbin Wang; Jeffrey C Miller; Yann Jouvenot; Kenneth A Kim; Olga Liu; Nathaniel Wang; Gary Lee; Victor V Bartsevich; Ya-Li Lee; Dmitry Y Guschin; Igor Rupniewski; Adam J Waite; Carmine Carpenito; Richard G Carroll; Jordan S Orange; Fyodor D Urnov; Edward J Rebar; Dale Ando; Philip D Gregory; James L Riley; Michael C Holmes; Carl H June
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases.
Nature biotechnology 2008;26(7):808-16.
2008: Samik Basu; Tatiana Golovina; Tatiana Mikheeva; Carl H June; James L Riley
Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(9):5794-8.
2008: Richard G Carroll; Carmine Carpenito; Xiaochuan Shan; Gwenn Danet-Desnoyers; Ronghua Liu; Shuguang Jiang; Steven M Albelda; Tatiana Golovina; George Coukos; James L Riley; Zdenka L Jonak; Carl H June
Distinct effects of IL-18 on the engraftment and function of human effector CD8 T cells and regulatory T cells.
PloS one 2008;3(9):e3289.
2007: Gabriela Plesa; Jihong Dai; Cliff Baytop; James L Riley; Carl H June; Una O'Doherty
Addition of deoxynucleosides enhances human immunodeficiency virus type 1 integration and 2LTR formation in resting CD4+ T cells.
Journal of virology 2007;81(24):13938-42.
2007: Jens M Chemnitz; Daniela Eggle; Julia Driesen; Sabine Classen; James L Riley; Svenja Debey-Pascher; Marc Beyer; Alexey Popov; Thomas Zander; Joachim L Schultze
RNA fingerprints provide direct evidence for the inhibitory role of TGFbeta and PD-1 on CD4+ T cells in Hodgkin lymphoma.
Blood 2007;110(9):3226-33.
2007: Elizabeth Hexner; Gwenn-Aël H Danet-Desnoyers; Yi Zhang; Dale M Frank; James L Riley; Bruce L Levine; David Porter; Carl H June; Stephen G Emerson
Umbilical cord blood xenografts in immunodeficient mice reveal that T cells enhance hematopoietic engraftment beyond overcoming immune barriers by stimulating stem cell differentiation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(10):1135-44.
2007: Bin LI; Arabinda Samanta; Xiaomin Song; Kathryn T Iacono; Patrick Brennan; Talal A Chatila; Giovanna Roncador; Alison H Banham; James L Riley; Qiang Wang; Yuan Shen; Sandra J Saouaf; Mark I Greene
FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease.
International immunology 2007;19(7):825-35.
2007: Megan M Suhoski; Tatiana N Golovina; Nicole A Aqui; Victoria C Tai; Angel Varela-Rohena; Michael C Milone; Richard G Carroll; James L Riley; Carl H June
Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(5):981-8.
2007: Richard V Parry; James L Riley; Stephen G Ward
Signalling to suit function: tailoring phosphoinositide 3-kinase during T-cell activation.
Trends in immunology 2007;28(4):161-8.
2007: Bin LI; Arabinda Samanta; Xiaomin Song; Kathryn T Iacono; Kathryn Bembas; Ran Tao; Samik Basu; James L Riley; Wayne W Hancock; Yuan Shen; Sandra J Saouaf; Mark I Greene
FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4571-6.
2007: James L Riley; Carl H June
The road to recovery: translating PD-1 biology into clinical benefit.
Trends in immunology 2007;28(2):48-50.
2006: Jens M Chemnitz; Anthony R Lanfranco; Inbal Braunstein; James L Riley
B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):6603-14.
2006: Jens M Chemnitz; Julia Driesen; Sabine Classen; James L Riley; Svenja Debey; Marc Beyer; Alexey Popov; Thomas Zander; Joachim L Schultze
Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma.
Cancer research 2006;66(2):1114-22.
2006: Shimin Hu; Ming-Qing Du; Sun-Mi Park; Allison Alcivar; Like Qu; Sanjeev Gupta; Jun Tang; Mathijs Baens; Hongtao Ye; Tae H Lee; Peter Marynen; James L Riley; Xiaolu Yang
cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas.
The Journal of clinical investigation 2006;116(1):174-81.
2005: Birgit Kovacs; Richard V Parry; Zhengyu Ma; Emily Fan; Debra K Shivers; Benjamin A Freiberg; Anna K Thomas; Robert Rutherford; Catherine A Rumbley; James L Riley; Terri H Finkel
Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(12):7848-54.
2005: Richard V Parry; Jens M Chemnitz; Kenneth A Frauwirth; Anthony R Lanfranco; Inbal Braunstein; Sumire V Kobayashi; Peter Linsley; Craig Thompson; James L Riley
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms.
Molecular and cellular biology 2005;25(21):9543-53.
2005: E E Perez; James L Riley; Richard G Carroll; D von Laer; Carl H June
Suppression of HIV-1 infection in primary CD4 T cells transduced with a self-inactivating lentiviral vector encoding a membrane expressed gp41-derived fusion inhibitor.
Clinical immunology (Orlando, Fla.) 2005;115(1):26-32.
2005: James L Riley; Carl H June
The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.
Blood 2005;105(1):13-21.
2004: Daniel E Bauer; Marian H Harris; David Plas; Julian J Lum; Peter S Hammerman; Jeffrey C Rathmell; James L Riley; Craig Thompson
Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(11):1303-5.
2004: Jens M Chemnitz; Richard V Parry; Kim E Nichols; Carl H June; James L Riley
SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):945-54.
2004: Marcela V Maus; Birgit Kovacs; William W Kwok; Gerald Nepom; Katia Schlienger; James L Riley; David Allman; Terri H Finkel; Carl H June
Extensive replicative capacity of human central memory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):6675-83.
2003: Graham Simmons; Andrew J Rennekamp; Ning Chai; Luk Vandenberghe; James L Riley; Paul Bates
Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection.
Journal of virology 2003;77(24):13433-8.
2003: Richard V Parry; Catherine A Rumbley; Luk Vandenberghe; Carl H June; James L Riley
CD28 and inducible costimulatory protein Src homology 2 binding domains show distinct regulation of phosphatidylinositol 3-kinase, Bcl-xL, and IL-2 expression in primary human CD4 T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):166-74.
2003: Katia Schlienger; Christina S Chu; Edward Y Woo; Patricia M Rivers; Alanna J Toll; Brian Hudson; Marcela V Maus; James L Riley; Yongwon Choi; George Coukos; Larry R Kaiser; Stephen C Rubin; Bruce L Levine; Richard G Carroll; Carl H June
TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted T cells specific for autologous tumor in late-stage ovarian cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(4):1517-27.
2003: Graham Simmons; Jacqueline D Reeves; Case C Grogan; Luk Vandenberghe; Frédéric Baribaud; J Charles Whitbeck; Emily Burke; Michael J Buchmeier; Elizabeth J Soilleux; James L Riley; Robert W Doms; Paul Bates; Stefan Pöhlmann
DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.
Virology 2003;305(1):115-23.
2003: Marcela V Maus; James L Riley; William W Kwok; Gerald Nepom; Carl H June
HLA tetramer-based artificial antigen-presenting cells for stimulation of CD4+ T cells.
Clinical immunology (Orlando, Fla.) 2003;106(1):16-22.
2002: Anna K Thomas; Marcela V Maus; Waleed S W Shalaby; Carl H June; James L Riley
A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes.
Clinical immunology (Orlando, Fla.) 2002;105(3):259-72.
2002: Birgit Kovacs; Marcela V Maus; James L Riley; Geo S Derimanov; Gary A Koretzky; Carl H June; Terri H Finkel
Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):15006-11.
2002: James L Riley; Mao Mao; Sumire Kobayashi; Matt Biery; Julja Burchard; Guy Cavet; Brian P Gregson; Carl H June; Peter Linsley
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11790-5.
2002: Kenneth A Frauwirth; James L Riley; Marian H Harris; Richard V Parry; Jeffrey C Rathmell; David Plas; Rebecca L Elstrom; Carl H June; Craig Thompson
The CD28 signaling pathway regulates glucose metabolism.
Immunity 2002;16(6):769-77.
2002: Edward Y Woo; Heidi Yeh; Christina S Chu; Katia Schlienger; Richard G Carroll; James L Riley; Larry R Kaiser; Carl H June
Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4272-6.
2002: Marcela V Maus; Anna K Thomas; Debra G B Leonard; David Allman; Kathakali Addya; Katia Schlienger; James L Riley; Carl H June
Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB.
Nature biotechnology 2002;20(2):143-8.
2001: James L Riley; Patrick J Blair; J T Musser; R Abe; K Tezuka; T Tsuji; Carl H June
ICOS costimulation requires IL-2 and can be prevented by CTLA-4 engagement.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(8):4943-8.
2000: James L Riley; Katia Schlienger; Patrick J Blair; BM Carreno; Nancy Craighead; D Kim; Richard G Carroll; Carl H June
Modulation of susceptibility to HIV-1 infection by the cytotoxic T lymphocyte antigen 4 costimulatory molecule.
The Journal of experimental medicine 2000;191(11):1987-97.
2000: Patrick J Blair; James L Riley; David M Harlan; R Abe; Douglas K Tadaki; Steven C Hoffmann; L White; T Francomano; S J Perfetto; Allan D Kirk; Carl H June
CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis.
The Journal of experimental medicine 2000;191(4):651-60.
2000: Anu Puri; James L Riley; D Kim; DW Ritchey; P Hug; KM Jernigan; Patrick P Rose; Robert Blumenthal; Richard G Carroll
Influenza virus upregulates CXCR4 expression in CD4+ cells.
AIDS research and human retroviruses 2000;16(1):19-25.
1999: Xiaodong Xiao; L Wu; Tzanko S Stantchev; Yan-Ru Feng; S Ugolini; H Chen; Z Shen; James L Riley; Christopher C Broder; Quentin J Sattentau; Dimiter S Dimitrov
Constitutive cell surface association between CD4 and CCR5.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7496-501.
1998: Bruce L Levine; Julio Cotte; C C Small; Richard G Carroll; James L Riley; Wendy B Bernstein; D E Van Epps; R A Hardwick; Carl H June
Large-scale production of CD4+ T cells from HIV-1-infected donors after CD3/CD28 costimulation.
Journal of hematotherapy 1998;7(5):437-48.
1998: James L Riley; Bruce L Levine; Nancy Craighead; T Francomano; D Kim; Richard G Carroll; Carl H June
Naïve and memory CD4 T cells differ in their susceptibilities to human immunodeficiency virus type 1 infection following CD28 costimulation: implicatip6s for transmission and pathogenesis.
Journal of virology 1998;72(10):8273-80.
1998: Richard G Carroll; James L Riley; Bruce L Levine; Patrick J Blair; DC St Louis; Carl H June
The role of co-stimulation in regulation of chemokine receptor expression and HIV-1 infection in primary T lymphocytes.
Seminars in immunology 1998;10(3):195-202.
1998: Patrick J Blair; James L Riley; Bruce L Levine; Kelvin P Lee; Nancy Craighead; T Francomano; S J Perfetto; G S Gray; BM Carreno; Carl H June
CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows Bcl-X(L) induction.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):12-5.
1997: James L Riley; Richard G Carroll; Bruce L Levine; Wendy B Bernstein; DC St Louis; O S Weislow; Carl H June
Intrinsic resistance to T cell infection with HIV type 1 induced by CD28 costimulation.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5545-53.
1997: Patrick J Blair; James L Riley; Richard G Carroll; DC St Louis; Bruce L Levine; B Saha; Kelvin P Lee; Peter J Perrin; David M Harlan; Carl H June
CD28 co-receptor signal transduction in T-cell activation.
Biochemical Society transactions 1997;25(2):651-7.
1997: Richard G Carroll; James L Riley; Bruce L Levine; Y Feng; S Kaushal; DW Ritchey; Wendy B Bernstein; O S Weislow; C R Brown; E A Berger; Carl H June; DC St Louis
Differential regulation of HIV-1 fusion cofactor expression by CD28 costimulation of CD4+ T cells.
Science (New York, N.Y.) 1997;276(5310):273-6.
1996: Bruce L Levine; Joseph Mosca; James L Riley; Richard G Carroll; Maryanne Vahey; L L Jagodzinski; K F Wagner; D L Mayers; Donald S. Burke; O S Weislow; DC St Louis; Carl H June
Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation.
Science (New York, N.Y.) 1996;272(5270):1939-43.