Tom Brown

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Glynne-Jones P; Boltryk R J; Hill M; Zhang F; Dong L; Wilkinson J S; Brown T; Melvin T; Harris N R
Multi-modal particle manipulator to enhance bead-based bioassays.
Rusling David A; Rachwal Phillip A; Brown Tom; Fox Keith R
The stability of triplex DNA is affected by the stability of the underlying duplex.
Ben Gaied Nouha; Zhao Zhengyun; Gerrard Simon R; Fox Keith R; Brown Tom
Potent triple helix stabilization by 5',3'-modified triplex-forming oligonucleotides.

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All Publications

2010: Glynne-Jones P; Boltryk R J; Hill M; Zhang F; Dong L; Wilkinson J S; Brown T; Melvin T; Harris N R
Multi-modal particle manipulator to enhance bead-based bioassays.
Ultrasonics 2010;50(2):235-9.
2009: Rusling David A; Rachwal Phillip A; Brown Tom; Fox Keith R
The stability of triplex DNA is affected by the stability of the underlying duplex.
Biophysical chemistry 2009;145(2-3):105-10.
2009: Ben Gaied Nouha; Zhao Zhengyun; Gerrard Simon R; Fox Keith R; Brown Tom
Potent triple helix stabilization by 5',3'-modified triplex-forming oligonucleotides.
Chembiochem : a European journal of chemical biology 2009;10(11):1839-51.
2009: Czolkos Ilja; Hannestad Jonas K; Jesorka Aldo; Kumar Ravindra; Brown Tom; Albinsson Bo; Orwar Owe
Platform for controlled supramolecular nanoassembly.
Nano letters 2009;9(6):2482-6.
2009: Yang Quan-Hong; Wang Qi; Gale Nittaya; Oton Claudio J; Cui Lan; Nandhakumar Iris S; Zhu Zhenping; Tang Zhiyuan; Brown Tom; Loh Wei H
Loosening the DNA wrapping around single-walled carbon nanotubes by increasing the strand length.
Nanotechnology 2009;20(19):195603.
2009: Börjesson Karl; Preus Søren; El-Sagheer Afaf H; Brown Tom; Albinsson Bo; Wilhelmsson L Marcus
Nucleic acid base analog FRET-pair facilitating detailed structural measurements in nucleic acid containing systems.
Journal of the American Chemical Society 2009;131(12):4288-93.
2009: El-Sagheer Afaf H; Brown Tom
Synthesis and polymerase chain reaction amplification of DNA strands containing an unnatural triazole linkage.
Journal of the American Chemical Society 2009;131(11):3958-64.
2009: Rusling David A; Peng Guomei; Srinivasan Natarajan; Fox Keith R; Brown Tom
DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine.
Nucleic acids research 2009;37(4):1288-96.
2009: Glynne-Jones Peter; J Boltryk Rosemary; Hill Martyn; Zhang Fan; Dong Liqin; Wilkinson James S; Melvin Tracy; R Harris Nicholas; Brown Tom
Flexible acoustic particle manipulation device with integrated optical waveguide for enhanced microbead assays.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 2009;25(2):285-91.
2008: Gale Nittaya; French David J; Howard Rebecca L; McDowell David G; Debenham Paul G; Brown Tom
Rapid typing of STRs in the human genome by HyBeacon melting.
Organic & biomolecular chemistry 2008;6(24):4553-9.
2008: Stevenson Ross; Baxter Helen C; Aitken Alastair; Brown Tom; Baxter Robert L
Binding of 14-3-3 proteins to a single stranded oligodeoxynucleotide aptamer.
Bioorganic chemistry 2008;36(5):215-9.
2008: Kocalka Petr; El-Sagheer Afaf H; Brown Tom
Rapid and efficient DNA strand cross-linking by click chemistry.
Chembiochem : a European journal of chemical biology 2008;9(8):1280-5.
2008: Rusling David A; Broughton-Head Victoria J; Tuck Alex; Khairallah Hannah; Osborne Sadie D; Brown Tom; Fox Keith R
Kinetic studies on the formation of DNA triplexes containing the nucleoside analogue 2'-O-(2-aminoethyl)-5-(3-amino-1-propynyl)uridine.
Organic & biomolecular chemistry 2008;6(1):122-9.
2008: Erkan Yavuz; Halma Kiona; Czolkos Ilja; Jesorka Aldo; Dommersnes Paul; Kumar Ravindra; Brown Tom; Orwar Owe
Controlled release of chol-TEG-DNA from Nano- and micropatterned SU-8 surfaces by a spreading lipid film.
Nano letters 2008;8(1):227-31.
2008: El-Sagheer Afaf H; Kumar Ravindra; Findlow Stuart; Werner Joern M; Lane Andrew N; Brown Tom
A very stable cyclic DNA miniduplex with just two base pairs.
Chembiochem : a European journal of chemical biology 2008;9(1):50-2.
2008: Sandin Peter; Börjesson Karl; Li Hong; Mårtensson Jerker; Brown Tom; Wilhelmsson L Marcus; Albinsson Bo
Characterization and use of an unprecedentedly bright and structurally non-perturbing fluorescent DNA base analogue.
Nucleic acids research 2008;36(1):157-67.
2008: Börjesson Karl; Tumpane John; Ljungdahl Thomas; Wilhelmsson L Marcus; Nordén Bengt; Brown Tom; Mårtensson Jerker; Albinsson Bo
A membrane anchored DNA-based energy/electron transfer assembly.
Nucleic acids symposium series (2004) 2008;(52):691.
2008: Lundberg Erik; Tumpane John; Kumar Ravindra; Sandin Peter; Gale Nittaya; Nandhakumar Iris S; Albinsson Bo; Lincoln Per; Wilhelmsson L Marcus; Brown Tom; Nordén Bengt
Addressable molecular node assembly--high information density DNA nanostructures.
Nucleic acids symposium series (2004) 2008;(52):683-4.
2008: Börjesson Karl; Sandin Peter; Albinsson Bo; Mårtensson Jerker; Brown Tom; Wilhelmsson L Marcus
Characterization and use of tricyclic fluorescent nucleic acid base analogues.
Nucleic acids symposium series (2004) 2008;(52):3-4.
2007: Tumpane John; Kumar Ravindra; Lundberg Erik P; Sandin Peter; Gale Nittaya; Nandhakumar Iris S; Albinsson Bo; Lincoln Per; Wilhelmsson L Marcus; Brown Tom; Nordén Bengt
Triplex addressability as a basis for functional DNA nanostructures.
Nano letters 2007;7(12):3832-9.
2007: Hammond Naomi; Koumi Peter; Langley G John; Lowe Alex; Brown Tom
Rapid mass spectrometric identification of human genomic polymorphisms using multiplexed photocleavable mass-tagged probes and solid phase capture.
Organic & biomolecular chemistry 2007;5(12):1878-85.
2007: Kumar Ravindra; El-Sagheer Afaf; Tumpane John; Lincoln Per; Wilhelmsson L Marcus; Brown Tom
Template-directed oligonucleotide strand ligation, covalent intramolecular DNA circularization and catenation using click chemistry.
Journal of the American Chemical Society 2007;129(21):6859-64.
2007: Rachwal Phillip A; Brown Tom; Fox Keith R
Sequence effects of single base loops in intramolecular quadruplex DNA.
FEBS letters 2007;581(8):1657-60.
2007: Rachwal Phillip A; Brown Tom; Fox Keith R
Effect of G-tract length on the topology and stability of intramolecular DNA quadruplexes.
Biochemistry 2007;46(11):3036-44.
2007: Durand Adeline; Brown Tom
Synthesis and properties of oligonucleotides containing a cholesterol thymidine monomer.
Nucleosides, nucleotides & nucleic acids 2007;26(6-7):785-94.
2007: Gerrard Simon R; Srinivasan Natarajan; Fox Keith R; Brown Tom
CG base pair recognition within DNA triple helices using N-methyl-3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1363-7.
2007: Brennan Lavinia; Peng Guomei; Srinivasan Natarajan; Fox Keith R; Brown Tom
2'-o-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1283-6.
2007: Li Hong; Broughton-Head Victoria J; Fox Keith R; Brown Tom
Photoinduced crosslinking of double-helical DNA by psoralen covalently linked to a triple helix-forming oligonucleotide under near-physiological conditions.
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):1005-9.
2007: Zhao Zhengyun; Peng Guomei; Michels Jan; Fox Keith R; Brown Tom
Synthesis of anthraquinone oligonucleotides for triplex stabilization.
Nucleosides, nucleotides & nucleic acids 2007;26(8-9):921-5.
2007: Rachwal Phillip A; Findlow I Stuart; Werner Joern M; Brown Tom; Fox Keith R
Intramolecular DNA quadruplexes with different arrangements of short and long loops.
Nucleic acids research 2007;35(12):4214-22.
2007: Sandin Peter; Lincoln Per; Brown Tom; Wilhelmsson L Marcus
Synthesis and oligonucleotide incorporation of fluorescent cytosine analogue tC: a promising nucleic acid probe.
Nature protocols 2007;2(3):615-23.
2006: Li Hong; Broughton-Head Victoria J; Peng Guomei; Powers Vicki E C; Ovens Matthew J; Fox Keith R; Brown Tom
Triplex staples: DNA double-strand cross-linking at internal and terminal sites using psoralen-containing triplex-forming oligonucleotides.
Bioconjugate chemistry 2006;17(6):1561-7.
2006: Rusling David A; Brown Tom; Fox Keith R
DNA triple-helix formation at target sites containing duplex mismatches.
Biophysical chemistry 2006;123(2-3):134-40.
2006: Hampshire Andrew J; Khairallah Hannah; Khalaf Abedawn I; Ebrahimabadi Abdolrasoul H; Waigh Roger D; Suckling Colin J; Brown Tom; Fox Keith R
DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B).
Bioorganic & medicinal chemistry letters 2006;16(13):3469-74.
2005: Rusling David A; Le Strat Loic; Powers Vicki E C; Broughton-Head Victoria J; Booth James; Lack Oliver; Brown Tom; Fox Keith R
Combining nucleoside analogues to achieve recognition of oligopurine tracts by triplex-forming oligonucleotides at physiological pH.
FEBS letters 2005;579(29):6616-20.
2005: Fox Keith R; Brown Tom
An extra dimension in nucleic acid sequence recognition.
Quarterly reviews of biophysics 2005;38(4):311-20.
2005: Ranasinghe Rohan T; Brown Tom
Fluorescence based strategies for genetic analysis.
Chemical communications (Cambridge, England) 2005;(44):5487-502.
2005: Brown Nicholas M; Rachwal Phillip A; Brown Tom; Fox Keith R
Exceptionally slow kinetics of the intramolecular quadruplex formed by the Oxytricha telomeric repeat.
Organic & biomolecular chemistry 2005;3(22):4153-7.
2005: May Jonathan P; Brown Lynda J; van Delft Ian; Thelwell Nicola; Harley Kate; Brown Tom
Synthesis and evaluation of a new non-fluorescent quencher in fluorogenic oligonucleotide probes for real-time PCR.
Organic & biomolecular chemistry 2005;3(14):2534-42.
2005: Dyadyusha L; Yin H; Jaiswal S; Brown T; Baumberg J J; Booy F P; Melvin T
Quenching of CdSe quantum dot emission, a new approach for biosensing.
Chemical communications (Cambridge, England) 2005;(25):3201-3.
2005: Ranasinghe Rohan T; Rusling David A; Powers Vicki E C; Fox Keith R; Brown Tom
Recognition of CG inversions in DNA triple helices by methylated 3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues.
Chemical communications (Cambridge, England) 2005;(20):2555-7.
2005: Wang Yang; Rusling David A; Powers Vicki E C; Lack Oliver; Osborne Sadie D; Fox Keith R; Brown Tom
Stable recognition of TA interruptions by triplex forming oligonucleotides containing a novel nucleoside.
Biochemistry 2005;44(15):5884-92.
2005: Booth James; Brown Tom; Vadhia Sunil J; Lack Oliver; Cummins W Jon; Trent John O; Lane Andrew N
Determining the origin of the stabilization of DNA by 5-aminopropynylation of pyrimidines.
Biochemistry 2005;44(12):4710-9.
2005: Sandin Peter; Wilhelmsson L Marcus; Lincoln Per; Powers Vicki E C; Brown Tom; Albinsson Bo
Fluorescent properties of DNA base analogue tC upon incorporation into DNA--negligible influence of neighbouring bases on fluorescence quantum yield.
Nucleic acids research 2005;33(16):5019-25.
2005: Rusling David A; Powers Vicki E C; Ranasinghe Rohan T; Wang Yang; Osborne Sadie D; Brown Tom; Fox Keith R
Four base recognition by triplex-forming oligonucleotides at physiological pH.
Nucleic acids research 2005;33(9):3025-32.
2004: James Peter L; Le Strat Loic; Ellervik Ulf; Bratwall Christina; Nordén Bengt; Brown Tom; Fox Keith R
Effects of a hairpin polyamide on DNA melting: comparison with distamycin and Hoechst 33258.
Biophysical chemistry 2004;111(3):205-12.
2004: Booth James; Cummins W Jon; Brown Tom
An analogue of adenine that forms an "A:T" base pair of comparable stability to G:C.
Chemical communications (Cambridge, England) 2004;(19):2208-9.
2004: Engman K Cecilia; Sandin Peter; Osborne Sadie; Brown Tom; Billeter Martin; Lincoln Per; Nordén Bengt; Albinsson Bo; Wilhelmsson L Marcus
DNA adopts normal B-form upon incorporation of highly fluorescent DNA base analogue tC: NMR structure and UV-Vis spectroscopy characterization.
Nucleic acids research 2004;32(17):5087-95.
2004: Osborne Sadie D; Powers Vicki E C; Rusling David A; Lack Oliver; Fox Keith R; Brown Tom
Selectivity and affinity of triplex-forming oligonucleotides containing 2'-aminoethoxy-5-(3-aminoprop-1-ynyl)uridine for recognizing AT base pairs in duplex DNA.
Nucleic acids research 2004;32(15):4439-47.
2004: Yin H B; Brown T; Wilkinson J S; Eason R W; Melvin T
Submicron patterning of DNA oligonucleotides on silicon.
Nucleic acids research 2004;32(14):e118.
2004: James Peter L; Merkina Elena E; Khalaf Abedawn I; Suckling Colin J; Waigh Roger D; Brown Tom; Fox Keith R
DNA sequence recognition by an isopropyl substituted thiazole polyamide.
Nucleic acids research 2004;32(11):3410-7.
2003: Keppler Melanie D; James Peter L; Neidle Stephen; Brown Tom; Fox Keith R
DNA sequence specificity of triplex-binding ligands.
European journal of biochemistry / FEBS 2003;270(24):4982-92.
2003: James Peter L; Brown Tom; Fox Keith R
Thermodynamic and kinetic stability of intermolecular triple helices containing different proportions of C+*GC and T*AT triplets.
Nucleic acids research 2003;31(19):5598-606.
2003: McKeen Catherine M; Brown Lynda J; Nicol Jamie T G; Mellor John M; Brown Tom
Synthesis of fluorophore and quencher monomers for use in scorpion primers and nucleic acid structural probes.
Organic & biomolecular chemistry 2003;1(13):2267-75.
2003: Dobson Neil; McDowell David G; French David J; Brown Lynda J; Mellor John M; Brown Tom
Synthesis of HyBeacons and dual-labelled probes containing 2'-fluorescent groups for use in genetic analysis.
Chemical communications (Cambridge, England) 2003;(11):1234-5.
2003: Gyi Jeffrey I; Gao Daquan; Conn Graeme L; Trent John O; Brown Tom; Lane Andrew N
The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications.
Nucleic acids research 2003;31(10):2683-93.
2003: Brown James; Brown Tom; Fox Keith R
Cleavage of fragments containing DNA mismatches by enzymic and chemical probes.
The Biochemical journal 2003;371(Pt 3):697-708.
2003: May Jonathan P; Brown Lynda J; Rudloff Ivo; Brown Tom
A new dark quencher for use in genetic analysis.
Chemical communications (Cambridge, England) 2003;(8):970-1.
2002: Solinas Antonio; Thelwell Nicola; Brown Tom
Intramolecular TaqMan probes for genetic analysis.
Chemical communications (Cambridge, England) 2002;(19):2272-3.
2002: Sollogoub Matthieu; Darby Richard A J; Cuenoud Bernard; Brown Tom; Fox Keith R
Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U.
Biochemistry 2002;41(23):7224-31.
2002: Darby Richard A J; Sollogoub Matthieu; McKeen Catherine; Brown Lynda; Risitano Antonina; Brown Nicholas; Barton Christopher; Brown Tom; Fox Keith R
High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler.
Nucleic acids research 2002;30(9):e39.
2001: Solinas A; Brown L J; McKeen C; Mellor J M; Nicol J; Thelwell N; Brown T
Duplex Scorpion primers in SNP analysis and FRET applications.
Nucleic acids research 2001;29(20):E96.
2001: Brown T; Mackey K
Analysis of RNA by northern and slot-blot hybridization.
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] 2001;Chapter 5():Unit 5.17.
2001: Brown T
Hybridization analysis of DNA blots.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2001;Chapter 10():Unit 10.6B.
2001: Brown T
Southern blotting.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2001;Chapter 10():Unit 10.6A.
2001: Brown T
Analysis of RNA by northern and slot-blot hybridization.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2001;Chapter 10():Unit 10.12.
2001: Brown T; Struhl K
Hybridization analysis of DNA blots.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2001;Appendix 4():Appendix 4H.
2001: Brown T
Southern blotting.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2001;Appendix 4():Appendix 4G.
2001: Brown J; Brown T; Fox K R
Affinity of mismatch-binding protein MutS for heteroduplexes containing different mismatches.
The Biochemical journal 2001;354(Pt 3):627-33.
2000: Thelwell N; Millington S; Solinas A; Booth J; Brown T
Mode of action and application of Scorpion primers to mutation detection.
Nucleic acids research 2000;28(19):3752-61.
2000: Fox K R; Allinson S L; Sahagun-Krause H; Brown T
Recognition of GT mismatches by Vsr mismatch endonuclease.
Nucleic acids research 2000;28(13):2535-40.
1999: Keppler M D; McKeen C M; Zegrocka O; Strekowski L; Brown T; Fox K R
DNA triple helix stabilisation by covalent attachment of a triplex-specific ligand.
Biochimica et biophysica acta 1999;1447(2-3):137-45.
1999: Gowers D M; Bijapur J; Brown T; Fox K R
DNA triple helix formation at target sites containing several pyrimidine interruptions: stabilization by protonated cytosine or 5-(1-propargylamino)dU.
Biochemistry 1999;38(41):13747-58.
1999: Bijapur J; Keppler M D; Bergqvist S; Brown T; Fox K R
5-(1-propargylamino)-2'-deoxyuridine (UP): a novel thymidine analogue for generating DNA triplexes with increased stability.
Nucleic acids research 1999;27(8):1802-9.
1999: Asensio J L; Brown T; Lane A N
Solution conformation of a parallel DNA triple helix with 5' and 3' triplex-duplex junctions.
Structure (London, England : 1993) 1999;7(1):1-11.
1999: Conn G L; Brown T; Leonard G A
The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solution.
Nucleic acids research 1999;27(2):555-61.
1999: Langley G J; Herniman J M; Davies N L; Brown T
Simplified sample preparation for the analysis of oligonucleotides by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry.
Rapid communications in mass spectrometry : RCM 1999;13(17):1717-23.
1998: Asensio J L; Brown T; Lane A N
Comparison of the solution structures of intramolecular DNA triple helices containing adjacent and non-adjacent CG.C+ triplets.
Nucleic acids research 1998;26(16):3677-86.
1998: Gyi J I; Lane A N; Conn G L; Brown T
The orientation and dynamics of the C2'-OH and hydration of RNA and DNA.RNA hybrids.
Nucleic acids research 1998;26(13):3104-10.
1998: Asensio J L; Lane A N; Dhesi J; Bergqvist S; Brown T
The contribution of cytosine protonation to the stability of parallel DNA triple helices.
Journal of molecular biology 1998;275(5):811-22.
1998: Gyi J I; Lane A N; Conn G L; Brown T
Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes.
Biochemistry 1998;37(1):73-80.
1997: Bonifacio G F; Brown T; Conn G L; Lane A N
Comparison of the electrophoretic and hydrodynamic properties of DNA and RNA oligonucleotide duplexes.
Biophysical journal 1997;73(3):1532-8.
1997: Conte M R; Conn G L; Brown T; Lane A N
Conformational properties and thermodynamics of the RNA duplex r(CGCAAAUUUGCG)2: comparison with the DNA analogue d(CGCAAATTTGCG)2.
Nucleic acids research 1997;25(13):2627-34.
1997: Moraru-Allen A A; Cassidy S; Asensio Alvarez J L; Fox K R; Brown T; Lane A N
Coralyne has a preference for intercalation between TA.T triples in intramolecular DNA triple helices.
Nucleic acids research 1997;25(10):1890-6.
1997: Sutton D H; Conn G L; Brown T; Lane A N
The dependence of DNase I activity on the conformation of oligodeoxynucleotides.
The Biochemical journal 1997;321 ( Pt 2)():481-6.
1996: Conte M R; Conn G L; Brown T; Lane A N
Hydration of the RNA duplex r(CGCAAAUUUGCG)2 determined by NMR.
Nucleic acids research 1996;24(19):3693-9.
1996: Gyi J I; Conn G L; Lane A N; Brown T
Comparison of the thermodynamic stabilities and solution conformations of DNA.RNA hybrids containing purine-rich and pyrimidine-rich strands with DNA and RNA duplexes.
Biochemistry 1996;35(38):12538-48.
1996: Finn P J; Gibson N J; Fallon R; Hamilton A; Brown T
Synthesis and properties of DNA-PNA chimeric oligomers.
Nucleic acids research 1996;24(17):3357-63.
1996: Boggon T J; Hancox E L; McAuley-Hecht K E; Connolly B A; Hunter W N; Brown T; Walker R T; Leonard G A
The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides.
Nucleic acids research 1996;24(5):951-61.
1995: Dautant A; Langlois d'Estaintot B; Gallois B; Brown T; Hunter W N
A trigonal form of the idarubicin:d(CGATCG) complex; crystal and molecular structure at 2.0 A resolution.
Nucleic acids research 1995;23(10):1710-6.
1995: Chen A; Powell L M; Dryden D T; Murray N E; Brown T
Tyrosine 27 of the specificity polypeptide of EcoKI can be UV crosslinked to a bromodeoxyuridine-substituted DNA target sequence.
Nucleic acids research 1995;23(7):1177-83.
1995: Leonard G A; Zhang S; Peterson M R; Harrop S J; Helliwell J R; Cruse W B; d'Estaintot B L; Kennard O; Brown T; Hunter W N
Self-association of a DNA loop creates a quadruplex: crystal structure of d(GCATGCT) at 1.8 A resolution.
Structure (London, England : 1993) 1995;3(4):335-40.
1995: Leonard G A; McAuley-Hecht K; Brown T; Hunter W N
Do C-H...O hydrogen bonds contribute to the stability of nucleic acid base pairs?
Acta crystallographica. Section D, Biological crystallography 1995;51(Pt 2):136-9.
1994: McAuley-Hecht K E; Leonard G A; Gibson N J; Thomson J B; Watson W P; Hunter W N; Brown T
Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairs.
Biochemistry 1994;33(34):10266-70.
1994: Leonard G A; McAuley-Hecht K E; Ebel S; Lough D M; Brown T; Hunter W N
Crystal and molecular structure of r(CGCGAAUUAGCG): an RNA duplex containing two G(anti).A(anti) base pairs.
Structure (London, England : 1993) 1994;2(6):483-94.
1994: Leonard G A; McAuley-Hecht K E; Gibson N J; Brown T; Watson W P; Hunter W N
Guanine-1,N6-ethenoadenine base pairs in the crystal structure of d(CGCGAATT(epsilon dA)GCG).
Biochemistry 1994;33(16):4755-61.
1994: Lane A; Ebel S y; Brown T
Properties of multiple G.A mismatches in stable oligonucleotide duplexes.
European journal of biochemistry / FEBS 1994;220(3):717-27.
1994: Ebel S; Brown T; Lane A N
Thermodynamic stability and solution conformation of tandem G.A mismatches in RNA and RNA.DNA hybrid duplexes.
European journal of biochemistry / FEBS 1994;220(3):703-15.
1993: Leonard G A; Hambley T W; McAuley-Hecht K; Brown T; Hunter W N
Anthracycline-DNA interactions at unfavourable base-pair triplet-binding sites: structures of d(CGGCCG)/daunomycin and d(TGGCCA)/adriamycin complexes.
Acta crystallographica. Section D, Biological crystallography 1993;49(Pt 5):458-67.
1993: Teigelkamp S; Ebel S; Will D W; Brown T; Beggs J D
Branched poly-labelled oligonucleotides: enhanced specificity of fork-shaped biotinylated oligoribonucleotides for antisense affinity selection.
Nucleic acids research 1993;21(19):4651-2.
1993: Lane A N; Ebel S; Brown T
NMR assignments and solution conformation of the DNA.RNA hybrid duplex d(GTGAACTT).r(AAGUUCAC).
European journal of biochemistry / FEBS 1993;215(2):297-306.
1993: Gallois B; d'Estaintot B L; Brown T; Hunter W N
The structure of an idarubicin-d(TGATCA) complex at high resolution.
Acta crystallographica. Section D, Biological crystallography 1993;49(Pt 3):311-7.
1993: Grzybowski J; Will D W; Randall R E; Smith C A; Brown T
Synthesis and antibody-mediated detection of oligonucleotides containing multiple 2,4-dinitrophenyl reporter groups.
Nucleic acids research 1993;21(8):1705-12.
1993: Lane A; Martin S R; Ebel S; Brown T
Solution conformation of a deoxynucleotide containing tandem G.A mismatched base pairs and 3'-overhanging ends in d(GTGAACTT)2.
Biochemistry 1993;32(14):3829.
1992: Ebel S; Lane A N; Brown T
Very stable mismatch duplexes: structural and thermodynamic studies on tandem G.A mismatches in DNA.
Biochemistry 1992;31(48):12083-6.
1992: Lane A; Martin S R; Ebel S; Brown T
Solution conformation of a deoxynucleotide containing tandem G.A mismatched base pairs and 3'-overhanging ends in d(GTGAACTT)2.
Biochemistry 1992;31(48):12087-95.
1992: Leonard G A; Booth E D; Hunter W N; Brown T
The conformational variability of an adenosine.inosine base-pair in a synthetic DNA dodecamer.
Nucleic acids research 1992;20(18):4753-9.
1992: Leonard G A; Guy A; Brown T; Téoule R; Hunter W N
Conformation of guanine-8-oxoadenine base pairs in the crystal structure of d(CGCGAATT(O8A)GCG).
Biochemistry 1992;31(36):8415-20.
1992: Langlois d'Estaintot B; Gallois B; Brown T; Hunter W N
The molecular structure of a 4'-epiadriamycin complex with d(TGATCA) at 1.7A resolution: comparison with the structure of 4'-epiadriamycin d(TGTACA) and d(CGATCG) complexes.
Nucleic acids research 1992;20(14):3561-6.
1992: MacKellar C; Graham D; Will D W; Burgess S; Brown T
Synthesis and physical properties of anti-HIV antisense oligonucleotides bearing terminal lipophilic groups.
Nucleic acids research 1992;20(13):3411-7.
1992: Borden K L; Jenkins T C; Skelly J V; Brown T; Lane A N
Conformational properties of the G.G mismatch in d(CGCGAATTGGCG)2 determined by NMR.
Biochemistry 1992;31(23):5411-22.
1992: Leonard G A; Brown T; Hunter W N
Anthracycline binding to DNA. High-resolution structure of d(TGTACA) complexed with 4'-epiadriamycin.
European journal of biochemistry / FEBS 1992;204(1):69-74.
1991: Lane A N; Jenkins T C; Brown D J; Brown T
N.m.r. determination of the solution conformation and dynamics of the A.G mismatch in the d(CGCAAATTGGCG)2 dodecamer.
The Biochemical journal 1991;279 ( Pt 1)():269-81.
1991: Will D W; Pritchard C E; Brown T
The synthesis of oligonucleotides that contain 2,4-dinitrophenyl reporter groups.
Carbohydrate research 1991;216():315-22.
1991: Lane A N; Jenkins T C; Brown T; Neidle S
Interaction of berenil with the EcoRI dodecamer d(CGCGAATTCGCG)2 in solution studied by NMR.
Biochemistry 1991;30(5):1372-85.
1990: Leonard G A; Thomson J; Watson W P; Brown T
High-resolution structure of a mutagenic lesion in DNA.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9573-6.
1990: Leonard G A; Booth E D; Brown T
Structural and thermodynamic studies on the adenine.guanine mismatch in B-DNA.
Nucleic acids research 1990;18(19):5617-23.
1990: Brown T; Leonard G A; Booth E D; Kneale G
Influence of pH on the conformation and stability of mismatch base-pairs in DNA.
Journal of molecular biology 1990;212(3):437-40.
1989: Brown T; Leonard G A; Booth E D; Chambers J
Crystal structure and stability of a DNA duplex containing A(anti).G(syn) base-pairs.
Journal of molecular biology 1989;207(2):455-7.
1989: Cruse W B; Aymani J; Kennard O; Brown T; Jack A G; Leonard G A
Refined crystal structure of an octanucleotide duplex with I.T. mismatched base pairs.
Nucleic acids research 1989;17(1):55-72.
1987: Corfield P W; Hunter W N; Brown T; Robinson P; Kennard O
Inosine.adenine base pairs in a B-DNA duplex.
Nucleic acids research 1987;15(19):7935-49.
1986: Cruse W B; Salisbury S A; Brown T; Cosstick R; Eckstein F; Kennard O
Chiral phosphorothioate analogues of B-DNA. The crystal structure of Rp-d[Gp(S)CpGp(S)CpGp(S)C].
Journal of molecular biology 1986;192(4):891-905.

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