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Fabienne Rajas

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Amandine Gautier-Stein; Fabienne Rajas; Maud Soty; Carine Zitoun; Julien Chilloux; Gilles Mithieux
Glucotoxicity induces glucose-6-phosphatase catalytic unit expression by acting on the interaction of HIF-1α with CREB-binding protein.
Celine Duraffourd; Amandine Gautier-Stein; Daisy Goncalves; Bleuenn Brusset; Dominique Chassard; Filipe De Vadder; Fabien Delaere; Adeline Duchampt; Armelle Penhoat; Fabienne Rajas; Anne Stefanutti; Gilles Mithieux
Mu-opioid receptors and dietary protein stimulate a gut-brain neural circuitry limiting food intake.
Elodie Mutel; Anne Stefanutti; Jean-André Tourette; Carine Zitoun; Aya Abdul-Wahed; Marta Amigó-Correig; Amandine Gautier-Stein; Isabelle Houberdon; Gilles Mithieux; Fabienne Rajas
Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon.

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All Publications

2012: Amandine Gautier-Stein; Fabienne Rajas; Maud Soty; Carine Zitoun; Julien Chilloux; Gilles Mithieux
Glucotoxicity induces glucose-6-phosphatase catalytic unit expression by acting on the interaction of HIF-1α with CREB-binding protein.
Diabetes 2012;61(10):2451-60.
2012: Celine Duraffourd; Amandine Gautier-Stein; Daisy Goncalves; Bleuenn Brusset; Dominique Chassard; Filipe De Vadder; Fabien Delaere; Adeline Duchampt; Armelle Penhoat; Fabienne Rajas; Anne Stefanutti; Gilles Mithieux
Mu-opioid receptors and dietary protein stimulate a gut-brain neural circuitry limiting food intake.
Cell 2012;150(2):377-88.
2011: Elodie Mutel; Anne Stefanutti; Jean-André Tourette; Carine Zitoun; Aya Abdul-Wahed; Marta Amigó-Correig; Amandine Gautier-Stein; Isabelle Houberdon; Gilles Mithieux; Fabienne Rajas
Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon.
Diabetes 2011;60(12):3121-31.
2011: Armelle Penhoat; Bruno Pillot; Fabienne Rajas; Anne Stefanutti; Marta Amigo-Correig; Elodie Mutel; Gilles Mithieux
Protein-induced satiety is abolished in the absence of intestinal gluconeogenesis.
Physiology & behavior 2011;105(1):89-93.
2011: Elodie Mutel; Aya Abdul-Wahed; Nirilanto Ramamonjisoa; Anne Stefanutti; Isabelle Houberdon; S Cavassila; Frank Pilleul; Olivier Beuf; Amandine Gautier-Stein; Armelle Penhoat; Gilles Mithieux; Fabienne Rajas
Targeted deletion of liver glucose-6 phosphatase mimics glycogen storage disease type 1a including development of multiple adenomas.
Journal of hepatology 2011;54(3):529-37.
2010: Johann Gout; Delphine Sarafian; Elodie Mutel; Michèle Vigier; Fabienne Rajas; Gilles Mithieux; Martine Begeot; Danielle Naville
Metabolic and melanocortin gene expression alterations in male offspring of obese mice.
Molecular and cellular endocrinology 2010;319(1-2):99-108.
2008: Johann Gout; Delphine Sarafian; Julien Tirard; Antonine Blondet; Michèle Vigier; Fabienne Rajas; Gilles Mithieux; Martine Begeot; Danielle Naville
Leptin infusion and obesity in mouse cause alterations in the hypothalamic melanocortin system.
Obesity (Silver Spring, Md.) 2008;16(8):1763-9.
2007: Fabienne Rajas; Hélène Jourdan-Pineau; Anne Stefanutti; Elham Abou Mrad; Patrick B Iynedjian; Gilles Mithieux
Immunocytochemical localization of glucose 6-phosphatase and cytosolic phosphoenolpyruvate carboxykinase in gluconeogenic tissues reveals unsuspected metabolic zonation.
Histochemistry and cell biology 2007;127(5):555-65.
2006: Gilles Mithieux; Fabienne Rajas; Carine Zitoun
Glucose utilization is suppressed in the gut of insulin-resistant high fat-fed rats and is restored by metformin.
Biochemical pharmacology 2006;72(12):1757-62.
2006: Amandine Gautier-Stein; Carine Zitoun; Enzo Lalli; Gilles Mithieux; Fabienne Rajas
Transcriptional regulation of the glucose-6-phosphatase gene by cAMP/vasoactive intestinal peptide in the intestine. Role of HNF4alpha, CREM, HNF1alpha, and C/EBPalpha.
The Journal of biological chemistry 2006;281(42):31268-78.
2006: Gilles Mithieux; Fabienne Rajas; Carine Zitoun
Glucose utilization is suppressed in the gut of insulin-resistant high fat-fed rats and is restored by metformin.
Biochemical pharmacology 2006;72(2):198-203.
2006: Gilles Mithieux; Amandine Gautier-Stein; Fabienne Rajas; Carine Zitoun
Contribution of intestine and kidney to glucose fluxes in different nutritional states in rat.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2006;143(2):195-200.
2005: Gilles Mithieux; Pierre Misery; Christophe Magnan; Bruno Pillot; Amandine Gautier-Stein; Christine Bernard; Fabienne Rajas; Carine Zitoun
Portal sensing of intestinal gluconeogenesis is a mechanistic link in the diminution of food intake induced by diet protein.
Cell metabolism 2005;2(5):321-9.
2005: Amandine Gautier-Stein; Gilles Mithieux; Fabienne Rajas
A distal region involving hepatocyte nuclear factor 4alpha and CAAT/enhancer binding protein markedly potentiates the protein kinase A stimulation of the glucose-6-phosphatase promoter.
Molecular endocrinology (Baltimore, Md.) 2005;19(1):163-74.
2004: Gilles Mithieux; Fabienne Rajas; Amandine Gautier-Stein
A novel role for glucose 6-phosphatase in the small intestine in the control of glucose homeostasis.
The Journal of biological chemistry 2004;279(43):44231-4.
2004: Gilles Mithieux; Isabelle Bady; Amandine Gautier; Martine Croset; Fabienne Rajas; Carine Zitoun
Induction of control genes in intestinal gluconeogenesis is sequential during fasting and maximal in diabetes.
American journal of physiology. Endocrinology and metabolism 2004;286(3):E370-5.
2003: Amandine Gautier-Stein; Claire Domon-Dell; Alexandre Calon; Isabelle Bady; Jean-Noel Freund; Gilles Mithieux; Fabienne Rajas
Differential regulation of the glucose-6-phosphatase TATA box by intestine-specific homeodomain proteins CDX1 and CDX2.
Nucleic acids research 2003;31(18):5238-46.
2002: Fabienne Rajas; Amandine Gautier; Isabelle Bady; Sandrine Montano; Gilles Mithieux
Polyunsaturated fatty acyl coenzyme A suppress the glucose-6-phosphatase promoter activity by modulating the DNA binding of hepatocyte nuclear factor 4 alpha.
The Journal of biological chemistry 2002;277(18):15736-44.
2001: Martine Croset; Fabienne Rajas; Carine Zitoun; J M Hurot; Sandrine Montano; Gilles Mithieux
Rat small intestine is an insulin-sensitive gluconeogenic organ.
Diabetes 2001;50(4):740-6.
2001: Bernard Portha; Marie-Hélène Giroix; Patricia Serradas; Marie-Noëlle Gangnerau; Jamileh Movassat; Fabienne Rajas; Danielle Bailbe; Cédric Plachot; Gilles Mithieux; JC Marie
beta-cell function and viability in the spontaneously diabetic GK rat: information from the GK/Par colony.
Diabetes 2001;50 Suppl 1():S89-93.
2000: Fabienne Rajas; Martine Croset; Carine Zitoun; Sandrine Montano; Gilles Mithieux
Induction of PEPCK gene expression in insulinopenia in rat small intestine.
Diabetes 2000;49(7):1165-8.
1999: Fabienne Rajas; N Bruni; Sandrine Montano; Carine Zitoun; Gilles Mithieux
The glucose-6 phosphatase gene is expressed in human and rat small intestine: regulation of expression in fasted and diabetic rats.
Gastroenterology 1999;117(1):132-9.
1999: N Bruni; Fabienne Rajas; Sandrine Montano; F Chevalier-Porst; Irène Maire; Gilles Mithieux
Enzymatic characterization of four new mutations in the glucose-6 phosphatase (G6PC) gene which cause glycogen storage disease type 1a.
Annals of human genetics 1999;63(Pt 2):141-6.
1999: N Daniele; Fabienne Rajas; Bernard Payrastre; G Mauco; Carine Zitoun; Gilles Mithieux
Phosphatidylinositol 3-kinase translocates onto liver endoplasmic reticulum and may account for the inhibition of glucose-6-phosphatase during refeeding.
The Journal of biological chemistry 1999;274(6):3597-601.
1999: J Trouillas; P Chevallier; Chantal Remy; Fabienne Rajas; Regis Cohen; A Calle; Elisabeth L Hooghe-Peters; Bernard Rousset
Differential actions of the dopamine agonist bromocriptine on growth of SMtTW tumors exhibiting a prolactin and/or a somatotroph cell phenotype: relation to dopamine D2 receptor expression.
Endocrinology 1999;140(1):13-21.
1998: Fabienne Rajas; M Delhase; M De La Hoya; Peggy Verdood; Jose Luis Castrillo; Elisabeth L Hooghe-Peters
Nuclear factor 1 regulates the distal silencer of the human PIT1/GHF1 gene.
The Biochemical journal 1998;333 ( Pt 1)():77-84.
1996: M Delhase; Jose Luis Castrillo; M de la Hoya; Fabienne Rajas; Elisabeth L Hooghe-Peters
AP-1 and Oct-1 transcription factors down-regulate the expression of the human PIT1/GHF1 gene.
The Journal of biological chemistry 1996;271(50):32349-58.
1996: Fabienne Rajas; V Gire; Bernard Rousset
Involvement of a membrane-bound form of glutamate dehydrogenase in the association of lysosomes to microtubules.
The Journal of biological chemistry 1996;271(47):29882-90.
1996: Pascale Vertongen; M Delhase; Fabienne Rajas; Jacqueline Trouillas; Elisabeth L Hooghe-Peters; Michal Svoboda; Patrick Robberecht
Pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide receptor subtypes are differently expressed in rat transplanted pituitary tumours (SMtTW) and in the normal gland.
Journal of molecular endocrinology 1996;16(3):239-48.
1995: M Delhase; Fabienne Rajas; P Verdood; C Remy; P Chevallier; Brigitte Velkeniers; Jacqueline Trouillas; Elisabeth L Hooghe-Peters
Prolactin and growth hormone mRNA and protein characterization in SMtTW rat pituitary tumours.
Journal of molecular endocrinology 1995;15(3):233-43.
1993: Fabienne Rajas; Bernard Rousset
A membrane-bound form of glutamate dehydrogenase possesses an ATP-dependent high-affinity microtubule-binding activity.
The Biochemical journal 1993;295 ( Pt 2)():447-55.
1993: Z Kostrouch; Françoise Bernier-Valentin; Y Munari-Silem; Fabienne Rajas; Rachida Rabilloud; Bernard Rousset
Thyroglobulin molecules internalized by thyrocytes are sorted in early endosomes and partially recycled back to the follicular lumen.
Endocrinology 1993;132(6):2645-53.
1991: Z Kostrouch; Y Munari-Silem; Fabienne Rajas; Françoise Bernier-Valentin; Bernard Rousset
Thyroglobulin internalized by thyrocytes passes through early and late endosomes.
Endocrinology 1991;129(4):2202-11.