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Jeferson Luis Franco

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Bruna Comparsi; Alcir L Dafre; Alessandro de Souza Prestes; Danúbia B dos Santos; Marcelo Farina; Jeferson Luis Franco; Daiane F Meinerz; Thaís Posser; Sílvio Terra Stefanello; Caroline Wagner; Michael Aschner; João B T Rocha
Diphenyl ditelluride targets brain selenoproteins in vivo: inhibition of cerebral thioredoxin reductase and glutathione peroxidase in mice after acute exposure.
D F Meinerz; Antonio L Braga; H C Braga; B Comparsi; Alcir L Dafre; M T de Paula; Marcelo Farina; Jeferson Luis Franco; J B T Rocha; A E Schmitz; M U Silva; P S Taube; Thaís Posser
Protective effects of organoselenium compounds against methylmercury-induced oxidative stress in mouse brain mitochondrial-enriched fractions.
Thaís Posser; Mariane Trindade de Paula; Jeferson Luis Franco; Rodrigo B Leal; João Batista Teixeira da Rocha
Diphenyl diselenide induces apoptotic cell death and modulates ERK1/2 phosphorylation in human neuroblastoma SH-SY5Y cells.

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All Publications

2012: Bruna Comparsi; Alcir L Dafre; Alessandro de Souza Prestes; Danúbia B dos Santos; Marcelo Farina; Jeferson Luis Franco; Daiane F Meinerz; Thaís Posser; Sílvio Terra Stefanello; Caroline Wagner; Michael Aschner; João B T Rocha
Diphenyl ditelluride targets brain selenoproteins in vivo: inhibition of cerebral thioredoxin reductase and glutathione peroxidase in mice after acute exposure.
Molecular and cellular biochemistry 2012;370(1-2):173-82.
2011: D F Meinerz; Antonio L Braga; H C Braga; B Comparsi; Alcir L Dafre; M T de Paula; Marcelo Farina; Jeferson Luis Franco; J B T Rocha; A E Schmitz; M U Silva; P S Taube; Thaís Posser
Protective effects of organoselenium compounds against methylmercury-induced oxidative stress in mouse brain mitochondrial-enriched fractions.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2011;44(11):1156-63.
2011: Thaís Posser; Mariane Trindade de Paula; Jeferson Luis Franco; Rodrigo B Leal; João Batista Teixeira da Rocha
Diphenyl diselenide induces apoptotic cell death and modulates ERK1/2 phosphorylation in human neuroblastoma SH-SY5Y cells.
Archives of toxicology 2011;85(6):645-51.
2010: Angelica Francesca Maris; Jeferson Luis Franco; Péricles Aruda Mitozo; Gislaine Paviani; Cristina Borowski; Rafael Trevisan; Marcela Uliano-Silva; Marcelo Farina; Alcir L Dafre
Gender effects of acute malathion or zinc exposure on the antioxidant response of rat hippocampus and cerebral cortex.
Basic & clinical pharmacology & toxicology 2010;107(6):965-70.
2010: Daniel Henrique Roos; Robson Luiz Puntel; Thiago Henrique Lugokenski; Rafael Porto Ineu; Denise Bohrer; Marilise E Burger; Jeferson Luis Franco; Marcelo Farina; Michael Aschner; João B T Rocha; Nilda B de Vargas Barbosa
Complex methylmercury-cysteine alters mercury accumulation in different tissues of mice.
Basic & clinical pharmacology & toxicology 2010;107(4):789-92.
2010: Thaís Posser; Peter R Dunkley; Phillip W Dickson; Jeferson Luis Franco
Human neuroblastoma cells transfected with tyrosine hydroxylase gain increased resistance to methylmercury-induced cell death.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(6):1498-503.
2010: Jeferson Luis Franco; Rafael Trevisan; Thais Posser; Daniela B B Trivella; Roberto Hoppe; Juliana Martins Rosa; Daniel Fernandes Dinslaken; Helena Decker; Carla Inês Tasca; Rodrigo Bainy Leal; Maria Risoleta Freire Marques; Afonso Celso Dias Bainy; Alcir Luiz Dafre
Biochemical alterations in caged Nile tilapia Oreochromis niloticus.
Ecotoxicology and environmental safety 2010;73(5):864-72.
2010: Patricia Souza Brocardo; Josiane Budni; Eloísa Pavesi; Jeferson Luis Franco; Marcela Uliano-Silva; Rafael Trevisan; Mariana G Terenzi; Alcir L Dafre; Ana Lúcia S Rodrigues
Folic acid administration prevents ouabain-induced hyperlocomotion and alterations in oxidative stress markers in the rat brain.
Bipolar disorders 2010;12(4):414-24.
2009: Jeferson Luis Franco; Thaís Posser; Peter R Dunkley; Phillip W Dickson; Jacó J Mattos; Roberta Martins; Afonso C D Bainy; Maria R F Marques; Alcir L Dafre; Marcelo Farina
Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase.
Free radical biology & medicine 2009;47(4):449-57.
2009: Jeferson Luis Franco; Thaís Posser; Jacó J Mattos; Rafael Trevisan; Patricia Souza Brocardo; Ana Lúcia S Rodrigues; Rodrigo B Leal; Marcelo Farina; Maria R F Marques; Afonso C D Bainy; Alcir L Dafre
Zinc reverses malathion-induced impairment in antioxidant defenses.
Toxicology letters 2009;187(3):137-43.
2008: Jeferson Luis Franco; Thaís Posser; Jacó J Mattos; Alejandro Sánchez-Chardi; Rafael Trevisan; Camila S Oliveira; Paulo S M Carvalho; Rodrigo B Leal; Maria R F Marques; Afonso C D Bainy; Alcir L Dafre
Biochemical alterations in juvenile carp (Cyprinus carpio) exposed to zinc: glutathione reductase as a target.
Marine environmental research 2008;66(1):88-9.
2008: Jeferson Luis Franco; Thaís Posser; Patricia Souza Brocardo; Rafael Trevisan; Marcela Uliano-Silva; Nelson H Gabilan; Adair R S Santos; Rodrigo B Leal; Ana Lúcia S Rodrigues; Marcelo Farina; Alcir L Dafre
Involvement of glutathione, ERK1/2 phosphorylation and BDNF expression in the antidepressant-like effect of zinc in rats.
Behavioural brain research 2008;188(2):316-23.
2008: Rafael Trevisan; Marcela Uliano-Silva; Pablo Pandolfo; Jeferson Luis Franco; Patricia Souza Brocardo; Adair R S Santos; Marcelo Farina; Ana Lúcia S Rodrigues; Reinaldo N Takahashi; Alcir L Dafre
Antioxidant and acetylcholinesterase response to repeated malathion exposure in rat cerebral cortex and hippocampus.
Basic & clinical pharmacology & toxicology 2008;102(4):365-9.
2008: Thaís Posser; Jeferson Luis Franco; Daiane Almeida dos Santos; Ana Paula Rigon; Marcelo Farina; Alcir Luis Dafré; João Batista Teixeira Rocha; Rodrigo B Leal
Diphenyl diselenide confers neuroprotection against hydrogen peroxide toxicity in hippocampal slices.
Brain research 2008;1199():138-47.
2008: James Stringari; Adriana K C Nunes; Jeferson Luis Franco; Denise Bohrer; Solange C Garcia; Alcir L Dafre; Dejan Milatovic; Diogo O Souza; João B T Rocha; Michael Aschner; Marcelo Farina
Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain.
Toxicology and applied pharmacology 2008;227(1):147-54.
2008: Aline P da Silva; Marcelo Farina; Jeferson Luis Franco; Alcir L Dafre; Jiri Kassa; Kamil Kuca
Temporal effects of newly developed oximes (K027, K048) on malathion-induced acetylcholinesterase inhibition and lipid peroxidation in mouse prefrontal cortex.
Neurotoxicology 2008;29(1):184-9.
2007: Samuel Vandresen-Filho; Bruno de Araújo Herculano; Jeferson Luis Franco; Carina Rodrigues Boeck; Alcir L Dafre; Carla I Tasca
Evaluation of glutathione metabolism in NMDA preconditioning against quinolinic acid-induced seizures in mice cerebral cortex and hippocampus.
Brain research 2007;1184():38-45.
2007: Jeferson Luis Franco; Hugo C Braga; James Stringari; Fabiana Cristina Missau; Thaís Posser; Beatriz G Mendes; Rodrigo B Leal; Adair R S Santos; Alcir L Dafre; Moacir Geraldo Pizzolatti; Marcelo Farina
Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin.
Chemical research in toxicology 2007;20(12):1919-26.
2007: Márcia C Carvalho; Jeferson Luis Franco; Heloisa Ghizoni; Karoline Kobus; Evelise M Nazari; João B T Rocha; Cristina W Nogueira; Alcir L Dafre; Yara M R Müller; Marcelo Farina
Effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on methylmercury-induced locomotor deficits and cerebellar toxicity in mice.
Toxicology 2007;239(3):195-203.
2007: Greice M R de S Lucena; Jeferson Luis Franco; Camila Mafalda Ribas; Mariângela S Azevedo; Flavia Carla Meotti; Vinicius M Gadotti; Alcir L Dafre; Adair R S Santos; Marcelo Farina
Cipura paludosa extract prevents methyl mercury-induced neurotoxicity in mice.
Basic & clinical pharmacology & toxicology 2007;101(2):127-31.
2007: Evaldo Reischl; Alcir L Dafre; Jeferson Luis Franco; Danilo Wilhelm-Filho
Distribution, adaptation and physiological meaning of thiols from vertebrate hemoglobins.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2007;146(1-2):22-53.
2007: Rodrigo Medeiros; Rui D S Prediger; Giselle F Passos; Pablo Pandolfo; Filipe S Duarte; Jeferson Luis Franco; Alcir L Dafre; Gabriella Di Giunta; Cláudia P Figueiredo; Reinaldo N Takahashi; Maria M Campos; João B Calixto
Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(20):5394-404.
2007: Patricia Souza Brocardo; Fabrício Assini; Jeferson Luis Franco; Pablo Pandolfo; Yara M R Müller; Reinaldo N Takahashi; Alcir L Dafre; Ana Lúcia S Rodrigues
Zinc attenuates malathion-induced depressant-like behavior and confers neuroprotection in the rat brain.
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(1):140-8.
2007: Jeferson Luis Franco; Hugo de Campos Braga; Adriana K C Nunes; Camila Mafalda Ribas; James Stringari; Aline P Silva; Solange C Garcia Pomblum; Angela M Moro; Denise Bohrer; Adair R S Santos; Alcir L Dafre; Marcelo Farina
Lactational exposure to inorganic mercury: evidence of neurotoxic effects.
Neurotoxicology and teratology 2007;29(3):360-7.
2007: Rui D S Prediger; Jeferson Luis Franco; Pablo Pandolfo; Rodrigo Medeiros; Filipe S Duarte; Gabriella Di Giunta; Cláudia P Figueiredo; Marcelo Farina; João B Calixto; Reinaldo N Takahashi; Alcir L Dafre
Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response.
Behavioural brain research 2007;177(2):205-13.
2006: Thaís Posser; Maria Beatriz Moretto; Alcir L Dafre; Marcelo Farina; João Batista Teixeira da Rocha; Cristina W Nogueira; Gilson Zeni; Jovino Dos Santos Ferreira; Rodrigo B Leal; Jeferson Luis Franco
Antioxidant effect of diphenyl diselenide against sodium nitroprusside (SNP) induced lipid peroxidation in human platelets and erythrocyte membranes: an in vitro evaluation.
Chemico-biological interactions 2006;164(1-2):126-35.
2006: Jeferson Luis Franco; Adriana Teixeira; Flavia Carla Meotti; Camila Mafalda Ribas; James Stringari; Solange C Garcia Pomblum; Angela M Moro; Denise Bohrer; André V Bairros; Alcir L Dafre; Adair R S Santos; Marcelo Farina
Cerebellar thiol status and motor deficit after lactational exposure to methylmercury.
Environmental research 2006;102(1):22-8.
2006: Jeferson Luis Franco; Daniela B B Trivella; Rafael Trevisan; Daniel F Dinslaken; Maria R F Marques; Afonso C D Bainy; Alcir L Dafre
Antioxidant status and stress proteins in the gills of the brown mussel Perna perna exposed to zinc.
Chemico-biological interactions 2006;160(3):232-40.
2005: Marcelo Farina; Jeferson Luis Franco; Camila Mafalda Ribas; Flavia Carla Meotti; Fabiana Cristina Missau; Moacir Geraldo Pizzolatti; Alcir L Dafre; Adair R S Santos
Protective effects of Polygala paniculata extract against methylmercury-induced neurotoxicity in mice.
The Journal of pharmacy and pharmacology 2005;57(11):1503-8.