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Michio Shimabukuro

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Michio Shimabukuro; Takeshi Soeki; Minoru Tabata; Shuichiro Takanashi; Munkhbaatar Dagvasumberel; Daiju Fukuda; Yoichiro Hirata; Tetsuya Kitagawa; Hirotsugu Kurobe; Hiromi Sato; Masataka Sata
Epicardial adipose tissue volume and adipocytokine imbalance are strongly linked to human coronary atherosclerosis.
Zhe Tian; Kimi Araki; Hiroyuki Hao; Yoichiro Hirata; Eiji Horio; Tsuyoshi Kadomatsu; Michio Kawasuji; Yoshihiro Komohara; Keishi Miyata; Hisashi Sakaguchi; Masataka Sata; Michio Shimabukuro; Minoru Tabata; Otowa Takahashi; Shuichiro Takanashi; Motohiro Takeya; Hirokazu Tazume; Yuichi Oike
Perivascular adipose tissue-secreted angiopoietin-like protein 2 (Angptl2) accelerates neointimal hyperplasia after endovascular injury.
Yoichiro Hirata; Tetsuya Kitagawa; Hirotsugu Kurobe; Yutaka Nakaya; Sachiko Nishimoto; Chika Nishio; Hiroshi Sakaue; Michio Shimabukuro; Takeshi Soeki; Kimie Tanaka; Etsuko Uematsu; Daiju Fukuda; Nagakatsu Harada; Masataka Sata
Exendin-4, a glucagon-like peptide-1 receptor agonist, attenuates neointimal hyperplasia after vascular injury.

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2013: Michio Shimabukuro; Takeshi Soeki; Minoru Tabata; Shuichiro Takanashi; Munkhbaatar Dagvasumberel; Daiju Fukuda; Yoichiro Hirata; Tetsuya Kitagawa; Hirotsugu Kurobe; Hiromi Sato; Masataka Sata
Epicardial adipose tissue volume and adipocytokine imbalance are strongly linked to human coronary atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(5):1077-84.
2013: Zhe Tian; Kimi Araki; Hiroyuki Hao; Yoichiro Hirata; Eiji Horio; Tsuyoshi Kadomatsu; Michio Kawasuji; Yoshihiro Komohara; Keishi Miyata; Hisashi Sakaguchi; Masataka Sata; Michio Shimabukuro; Minoru Tabata; Otowa Takahashi; Shuichiro Takanashi; Motohiro Takeya; Hirokazu Tazume; Yuichi Oike
Perivascular adipose tissue-secreted angiopoietin-like protein 2 (Angptl2) accelerates neointimal hyperplasia after endovascular injury.
Journal of molecular and cellular cardiology 2013;57():1-12.
2013: Yoichiro Hirata; Tetsuya Kitagawa; Hirotsugu Kurobe; Yutaka Nakaya; Sachiko Nishimoto; Chika Nishio; Hiroshi Sakaue; Michio Shimabukuro; Takeshi Soeki; Kimie Tanaka; Etsuko Uematsu; Daiju Fukuda; Nagakatsu Harada; Masataka Sata
Exendin-4, a glucagon-like peptide-1 receptor agonist, attenuates neointimal hyperplasia after vascular injury.
European journal of pharmacology 2013;699(1-3):106-11.
2013: Yoichiro Hirata; Tetsuya Kitagawa; Hirotsugu Kurobe; Kunio Matsumoto; Mizuho Nakayama; Yoshiki Sakai; Michio Shimabukuro; Takeshi Soeki; Etsuko Uematsu; Shusuke Yagi; Hirotsugu Yamada; Daiju Fukuda; Masataka Sata
Beneficial effect of a synthetic prostacyclin agonist, ONO-1301, in rat autoimmune myocarditis model.
European journal of pharmacology 2013;699(1-3):81-7.
2013: Michio Shimabukuro; Takeshi Soeki; Shin-Ichiro Taira; Koichi Yabiku; Shusuke Yagi; Ken Yamakawa; Hisashi Yoshida; Munkhbaatar Dagvasumberel; Daiju Fukuda; Moritake Higa; Masayoshi Ishida; Chisayo Kozuka; Hiroaki Masuzaki; Sachiko Matsumoto; Masataka Sata
Ectopic fat deposition and global cardiometabolic risk: New paradigm in cardiovascular medicine.
The journal of medical investigation : JMI 2013;60(1-2):1-14.
2012: Asuka Shiota; Takeshi Soeki; Etsuko Uematsu; Hiromi Sato; Michio Shimabukuro; Daiju Fukuda; Yoichiro Hirata; Hirotsugu Kurobe; Hiroaki Masuzaki; Yutaka Nakaya; Hiroshi Sakaue; Masataka Sata
Activation of AMPK-Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects.
European journal of pharmacology 2012;692(1-3):84-90.
2012: Michio Shimabukuro; Daiju Fukuda; Masataka Sata
[Endothelial dysfunction].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 5():236-42.
2012: Michio Shimabukuro
[Insulin resistance and free fatty acid].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 3():185-90.
2012: Ken Yamakawa; Hisashi Yoshida; Michio Shimabukuro; Shinichiro Ueda; Osamu Arasaki; Tomohiro Asahi; Moritake Higa; Namio Higa; Tohru Higa; Hiroaki Masuzaki; Kageyuki Ohba; Yoshito Oshiro; Taro Saito; Masataka Sata
Eicosapentaenoic Acid supplementation changes Fatty Acid composition and corrects endothelial dysfunction in hyperlipidemic patients.
Cardiology research and practice 2012;2012():754181.
2012: Asuka Shiota; Takeshi Soeki; Etsuko Uematsu; Hiromi Sato; Michio Shimabukuro; Iichiro Shimomura; Daiju Fukuda; Yoichiro Hirata; Hirotsugu Kurobe; Norikazu Maeda; Hiroaki Masuzaki; Hiroshi Sakaue; Masataka Sata
Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice.
Cardiovascular diabetology 2012;11():139.
2012: Munkhbaatar Dagvasumberel; Daiju Fukuda; Masafumi Harada; Yoichiro Hirata; Takashi Iwase; Tetsuya Kitagawa; Hirotsugu Kurobe; Kenya Kusunose; Toshiyuki Niki; Takeshi Nishiuchi; Michio Shimabukuro; Takeshi Soeki; Shoichiro Takao; Yoshio Taketani; Noriko Tomita; Junji Ueno; Tetsuzo Wakatsuki; Shusuke Yagi; Hirotsugu Yamada; Koji Yamaguchi; Masataka Sata
Gender disparities in the association between epicardial adipose tissue volume and coronary atherosclerosis: a 3-dimensional cardiac computed tomography imaging study in Japanese subjects.
Cardiovascular diabetology 2012;11():106.
2012: Michio Shimabukuro; Hiroaki Masuzaki; Masataka Sata
Intensive glucose lowering in cardiovascular risk management - unsolved questions - .
Circulation journal : official journal of the Japanese Circulation Society 2012;76(3):593-5.
2011: Kentaro Nakamura; Michio Shimabukuro; Mitsuaki Takami; Ichiro Chinen; Satoshi Higa; Sugako Ishigaki; Takehiko Keida; Akira Maesato; Hiroaki Masuzaki
Effective prediction of response to cardiac resynchronization therapy using a novel program of gated myocardial perfusion single photon emission computed tomography.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2011;13(12):1731-7.
2011: Michio Shimabukuro; Tadao Shimabukuro; H Tanaka; Ken Yamakawa; Moritake Higa; H Masuzaki
Distinct effects of pitavastatin and atorvastatin on lipoprotein subclasses in patients with Type 2 diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 2011;28(7):856-64.
2011: Michio Shimabukuro; Ken Yamakawa; Hiroaki Masuzaki; Masataka Sata
[Obesity: Progress in diagnosis and treatment topics, IV. Recent topics; 1. Ectopic fat disposition and lipotoxicity].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(4):983-8.
2011: Michio Shimabukuro; Namio Higa; Tomohiro Asahi; Ken Yamakawa; Yoshito Oshiro; Moritake Higa; Hiroaki Masuzaki
Impaired glucose tolerance, but not impaired fasting glucose, underlies left ventricular diastolic dysfunction.
Diabetes care 2011;34(3):686-90.
2010: Yosuke Okuno; Morihiro Matsuda; Yugo Miyata; Atsunori Fukuhara; Ryutaro Komuro; Michio Shimabukuro; Iichiro Shimomura
Human catalase gene is regulated by peroxisome proliferator activated receptor-gamma through a response element distinct from that of mouse.
Endocrine journal 2010;57(4):303-9.
2009: Mitsuhisa Tabata; Tsuyoshi Kadomatsu; Shigetomo Fukuhara; Keishi Miyata; Yasuhiro Ito; Motoyoshi Endo; Takashi Urano; Hui Juan Zhu; Hiroto Tsukano; Hirokazu Tazume; Koichi Kaikita; Kazuya Miyashita; Takao Iwawaki; Michio Shimabukuro; Kazuhiko Sakaguchi; Takaaki Ito; Naomi Nakagata; Tetsuya Yamada; Hideki Katagiri; Masato Kasuga; Yukio Ando; Hisao Ogawa; Naoki Mochizuki; Hiroshi Itoh; Toshio Suda; Yuichi Oike
Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance.
Cell metabolism 2009;10(3):178-88.
2009: Michio Shimabukuro
Cardiac adiposity and global cardiometabolic risk: new concept and clinical implication.
Circulation journal : official journal of the Japanese Circulation Society 2009;73(1):27-34.
2008: Yasutaka Maeda; Toyoshi Inoguchi; Hirohito Tsubouchi; Fumi Sawada; Shuji Sasaki; Masakazu Fujii; Ryoko Saito; Toshihiko Yanase; Michio Shimabukuro; Hajime Nawata; Ryoichi Takayanagi
High prevalence of peripheral arterial disease diagnosed by low ankle-brachial index in Japanese patients with diabetes: the Kyushu Prevention Study for Atherosclerosis.
Diabetes research and clinical practice 2008;82(3):378-82.
2008: Yosuke Okuno; Morihiro Matsuda; Hironori Kobayashi; Kentaro Morita; Emi Suzuki; Atsunori Fukuhara; Ryutaro Komuro; Michio Shimabukuro; Iichiro Shimomura
Adipose expression of catalase is regulated via a novel remote PPARgamma-responsive region.
Biochemical and biophysical research communications 2008;366(3):698-704.
2008: Kaoru Okishige; Hiroki Uehara; Naoto Miyagi; Kentarou Nakamura; Kouji Azegami; Hirofumi Wakimoto; Kageyuki Ohba; Kenzo Hirao; Michio Shimabukuro; Mistuaki Isobe
Clinical study of the acute effects of intravenous nifekalant on the defibrillation threshold in patients with persistent and paroxysmal atrial fibrillation.
Circulation journal : official journal of the Japanese Circulation Society 2008;72(1):76-80.
2007: Michio Shimabukuro; Isabel Chinen; Naomi Higa; Nobuyuki Takasu; Ken Yamakawa; Shinichiro Ueda
Effects of dietary composition on postprandial endothelial function and adiponectin concentrations in healthy humans: a crossover controlled study.
The American journal of clinical nutrition 2007;86(4):923-8.
2007: Munehide Matsuhisa; Yoshimitsu Yamasaki; Masanori Emoto; Michio Shimabukuro; Shinichiro Ueda; Tohru Funahashi; Yuji Matsuzawa
A novel index of insulin resistance determined from the homeostasis model assessment index and adiponectin levels in Japanese subjects.
Diabetes research and clinical practice 2007;77(1):151-4.
2007: Michio Shimabukuro; Naomi Higa; Yoshito Oshiro; Tomohiro Asahi; Nobuyuki Takasu
Diagnostic utility of brain-natriuretic peptide for left ventricular diastolic dysfunction in asymptomatic type 2 diabetic patients.
Diabetes, obesity & metabolism 2007;9(3):323-9.
2007: Michio Shimabukuro; Hideaki Tanaka; Takeshi Shimabukuro
Effects of telmisartan on fat distribution in individuals with the metabolic syndrome.
Journal of hypertension 2007;25(4):841-8.
2007: Michio Shimabukuro
Clinical diagnosis of metabolic syndrome 2. Lipotoxicity as a mechanism of the metabolic syndrome.
Internal medicine (Tokyo, Japan) 2007;46(16):1285.
2007: Isabel Chinen; Michio Shimabukuro; Ken Yamakawa; Naomi Higa; Toshihiro Matsuzaki; Katsuhiko Noguchi; Shinichiro Ueda; Matao Sakanashi; Nobuyuki Takasu
Vascular lipotoxicity: endothelial dysfunction via fatty-acid-induced reactive oxygen species overproduction in obese Zucker diabetic fatty rats.
Endocrinology 2007;148(1):160-5.
2006: Michio Shimabukuro
[Appetite and feeding regulation by free fatty acid].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 9():116-20.
2006: Koichi Fujita; Hitoshi Nishizawa; Tohru Funahashi; Iichiro Shimomura; Michio Shimabukuro
Systemic oxidative stress is associated with visceral fat accumulation and the metabolic syndrome.
Circulation journal : official journal of the Japanese Circulation Society 2006;70(11):1437-42.
2006: Michio Shimabukuro
[Metabolic syndrome and lipotoxicity].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2006;95(9):1721-5.
2006: Michio Shimabukuro; Naomi Higa; Nobuyuki Takasu
Comparison of the antioxidant and vascular effects of gliclazide and glibenclamide in Type 2 diabetic patients: a randomized crossover study.
Journal of diabetes and its complications 2006;20(3):179-83.
2006: Moritake Higa; Michio Shimabukuro; Yoshinori Shimajiri; Nobuyuki Takasu; Tetsuharu Shinjyo; T Inaba
Protein kinase B/Akt signalling is required for palmitate-induced beta-cell lipotoxicity.
Diabetes, obesity & metabolism 2006;8(2):228-33.
2006: Michio Shimabukuro; Naomi Higa; Isabel Chinen; Ken Yamakawa; Nobuyuki Takasu
Effects of a single administration of acarbose on postprandial glucose excursion and endothelial dysfunction in type 2 diabetic patients: a randomized crossover study.
The Journal of clinical endocrinology and metabolism 2006;91(3):837-42.
2005: Saiko Watanabe; Tatsuya Tagawa; Ken Yamakawa; Michio Shimabukuro; Shinichiro Ueda
Inhibition of the renin-angiotensin system prevents free fatty acid-induced acute endothelial dysfunction in humans.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(11):2376-80.
2005: Munesada Yamakawa; Masanori Sunagawa; Michio Shimabukuro; Naomi Higa; Nobuyuki Takasu; Tadayoshi Kosugi
Effect of sodium channel blocker, pilsicainide hydrochloride, on net inward current of atrial myocytes in thyroid hormone toxicosis rats.
Thyroid : official journal of the American Thyroid Association 2005;15(7):653-9.
2005: Hideaki Tanaka; Takeshi Shimabukuro; Michio Shimabukuro
High prevalence of metabolic syndrome among men in Okinawa.
Journal of atherosclerosis and thrombosis 2005;12(5):284-8.
2005: Masanori Sunagawa; Munesada Yamakawa; Michio Shimabukuro; Naomi Higa; Nobuyuki Takasu; Tadayoshi Kosugi
Electrophysiologic characteristics of atrial myocytes in levo-thyroxine-treated rats.
Thyroid : official journal of the American Thyroid Association 2005;15(1):3-11.
2004: Shigetada Furukawa; Takuya Fujita; Michio Shimabukuro; Masanori Iwaki; Yukio Yamada; Yoshimitsu Nakajima; Osamu Nakayama; Makoto Makishima; Morihiro Matsuda; Iichiro Shimomura
Increased oxidative stress in obesity and its impact on metabolic syndrome.
The Journal of clinical investigation 2004;114(12):1752-61.
2004: Takeshi Tohma; Michio Shimabukuro; Yoshito Oshiro; Munesada Yamakawa; Yoshinori Shimajiri; Nobuyuki Takasu
Cilostazol, a phosphodiesterase inhibitor, reduces microalbuminuria in the insulin-resistant Otsuka Long-Evans Tokushima Fatty rat.
Metabolism: clinical and experimental 2004;53(11):1405-10.
2004: M Higa; Nobuyuki Takasu; T Tamanaha; K Nakamura; Michio Shimabukuro; T Sasara; M Tawata
Nitroglycerin spray rapidly improves pain in a patient with chronic painful diabetic neuropathy.
Diabetic medicine : a journal of the British Diabetic Association 2004;21(9):1053-4.
2004: Michio Shimabukuro; Naomi Higa; Nobuyuki Takasu; T Tagawa; S Ueda
A single dose of nateglinide improves post-challenge glucose metabolism and endothelial dysfunction in Type 2 diabetic patients.
Diabetic medicine : a journal of the British Diabetic Association 2004;21(9):983-6.
2004: Michio Shimabukuro; Naomi Higa; Tomohiro Asahi; Yoshito Oshiro; Nobuyuki Takasu
Fluvastatin improves endothelial dysfunction in overweight postmenopausal women through small dense low-density lipoprotein reduction.
Metabolism: clinical and experimental 2004;53(6):733-9.
2003: Michio Shimabukuro; Naomi Higa; Tomohiro Asahi; Yoshito Oshiro; Nobuyuki Takasu; Tatsuya Tagawa; Shinichiro Ueda; Iichiro Shimomura; Tohru Funahashi; Yuji Matsuzawa
Hypoadiponectinemia is closely linked to endothelial dysfunction in man.
The Journal of clinical endocrinology and metabolism 2003;88(7):3236-40.
2003: Yoshinori Shimajiri; Michio Shimabukuro; Takeaki Tomoyose; Hiroyuki Yogi; Ichiro Komiya; Nobuyuki Takasu
PAX4 mutation (R121W) as a prodiabetic variant in Okinawans.
Biochemical and biophysical research communications 2003;302(2):342-4.
2002: T Ikema; Yoshinori Shimajiri; Ichiro Komiya; M Tawata; S Sunakawa; Hiroyuki Yogi; Michio Shimabukuro; Nobuyuki Takasu
Identification of three new mutations of the HNF-1 alpha gene in Japanese MODY families.
Diabetologia 2002;45(12):1713-8.
2002: Mari Fukuchi; Michio Shimabukuro; Yoshinori Shimajiri; Yoshito Oshiro; Moritake Higa; Hiromitsu Akamine; Ichiro Komiya; Nobuyuki Takasu
Evidence for a deficient pancreatic beta-cell response in a rat model of hyperthyroidism.
Life sciences 2002;71(9):1059-70.
2002: Moritake Higa; Michio Shimabukuro; Mari Fukuchi; Ichiro Komiya; Nobuyuki Takasu
Atrophic change of rat salivary gland during adenovirus-induced hyperleptinemia.
Biochemical and biophysical research communications 2002;291(3):675-9.
2001: Tomohiro Asahi; Michio Shimabukuro; Yoshito Oshiro; H Yoshida; Nobuyuki Takasu
Cilazapril prevents cardiac hypertrophy and postischemic myocardial dysfunction in hyperthyroid rats.
Thyroid : official journal of the American Thyroid Association 2001;11(11):1009-15.
2001: Yoshito Oshiro; Michio Shimabukuro; Nobuyuki Takasu; Tomohiro Asahi; Ichiro Komiya; H Yoshida
Triiodothyronine concomitantly inhibits calcium overload and postischemic myocardial stunning in diabetic rats.
Life sciences 2001;69(16):1907-18.
2000: Ichiro Komiya; T Yamada; Masaki Takara; T Asawa; Michio Shimabukuro; T Nishimori; Nobuyuki Takasu
Lys(173)Arg and -344T/C variants of CYP11B2 in Japanese patients with low-renin hypertension.
Hypertension 2000;35(3):699-703.
2000: YT Zhou; Paul A Grayburn; A Karim; Michio Shimabukuro; M Higa; Danielle Baetens; Lelio Orci; Roger H Unger
Lipotoxic heart disease in obese rats: implications for human obesity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1784-9.
1999: May-Yun Wang; Michio Shimabukuro; Young Lee; KY Trinh; J L Chen; Christopher B Newgard; Roger H Unger
Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function.
Diabetes 1999;48(5):1020-5.
1998: Michio Shimabukuro; M Higa; YT Zhou; May-Yun Wang; Christopher B Newgard; Roger H Unger
Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression.
The Journal of biological chemistry 1998;273(49):32487-90.
1998: YT Zhou; Michio Shimabukuro; Young Lee; K Koyama; M Higa; T Ferguson; Roger H Unger
Enhanced de novo lipogenesis in the leptin-unresponsive pancreatic islets of prediabetic Zucker diabetic fatty rats: role in the pathogenesis of lipotoxic diabetes.
Diabetes 1998;47(12):1904-8.
1998: May-Yun Wang; K Koyama; Michio Shimabukuro; David J Mangelsdorf; Christopher B Newgard; Roger H Unger
Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11921-6.
1998: K Koyama; Michio Shimabukuro; Guoxun Chen; May-Yun Wang; Young Lee; Pushpa S Kalra; M G Dube; SP Kalra; Christopher B Newgard; Roger H Unger
Resistance to adenovirally induced hyperleptinemia in rats. Comparison of ventromedial hypothalamic lesions and mutated leptin receptors.
The Journal of clinical investigation 1998;102(4):728-33.
1998: Michio Shimabukuro; May-Yun Wang; YT Zhou; Christopher B Newgard; Roger H Unger
Protection against lipoapoptosis of beta cells through leptin-dependent maintenance of Bcl-2 expression.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9558-61.
1998: YT Zhou; Michio Shimabukuro; May-Yun Wang; Young Lee; M Higa; J L Milburn; Christopher B Newgard; Roger H Unger
Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8898-903.
1998: K Yoneda; Nobuyuki Takasu; Satoshi Higa; C Oshiro; Yoshito Oshiro; Michio Shimabukuro; Tomohiro Asahi
Direct effects of thyroid hormones on rat coronary artery: nongenomic effects of triiodothyronine and thyroxine.
Thyroid : official journal of the American Thyroid Association 1998;8(7):609-13.
1998: Michio Shimabukuro; YT Zhou; Moshe Levi; Roger H Unger
Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2498-502.
1998: Michio Shimabukuro; YT Zhou; Young Lee; Roger H Unger
Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats.
The Journal of biological chemistry 1998;273(6):3547-50.
1998: May-Yun Wang; K Koyama; Michio Shimabukuro; Christopher B Newgard; Roger H Unger
OB-Rb gene transfer to leptin-resistant islets reverses diabetogenic phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(2):714-8.
1997: YT Zhou; Michio Shimabukuro; Young Lee; K Koyama; F Trieu; Roger H Unger
Leptin normalizes the impaired response of proinsulin mRNA to long chain fatty acids in heterozygous Zucker diabetic fatty rats.
The Journal of biological chemistry 1997;272(41):25648-51.
1997: Michio Shimabukuro; K Koyama; Young Lee; Roger H Unger
Leptin- or troglitazone-induced lipopenia protects islets from interleukin 1beta cytotoxicity.
The Journal of clinical investigation 1997;100(7):1750-4.
1997: Michio Shimabukuro; YT Zhou; Young Lee; Roger H Unger
Induction of uncoupling protein-2 mRNA by troglitazone in the pancreatic islets of Zucker diabetic fatty rats.
Biochemical and biophysical research communications 1997;237(2):359-61.
1997: K Koyama; G Chen; M Y Wang; Young Lee; Michio Shimabukuro; C B Newgard; Roger H Unger
beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy.
Diabetes 1997;46(8):1276-80.
1997: Michio Shimabukuro; M Ohneda; Young Lee; Roger H Unger
Role of nitric oxide in obesity-induced beta cell disease.
The Journal of clinical investigation 1997;100(2):290-5.
1997: YT Zhou; Michio Shimabukuro; K Koyama; Young Lee; May-Yun Wang; F Trieu; Christopher B Newgard; Roger H Unger
Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6386-90.
1997: Michio Shimabukuro; K Koyama; Guoxun Chen; May-Yun Wang; F Trieu; Young Lee; Christopher B Newgard; Roger H Unger
Direct antidiabetic effect of leptin through triglyceride depletion of tissues.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4637-41.
1996: Michio Shimabukuro; T Chibana; H Yoshida; F Nagamine; N Takasu
Sustained improvement of pulmonary haemodynamics with low-dose of nifedipine in primary pulmonary hypertension.
European heart journal 1996;17(12):1911-2.
1996: Michio Shimabukuro; T Chibana; H Yoshida; F Nagamine; I Komiya; Nobuyuki Takasu
Increased QT dispersion and cardiac adrenergic dysinnervation in diabetic patients with autonomic neuropathy.
The American journal of cardiology 1996;78(9):1057-9.
1996: Michio Shimabukuro; Satoshi Higa; T Shinzato; H Yoshida; F Nagamine; K Takashiba; Nobuyuki Takasu
Successful repair of intimal dissection following coronary angioplasty with a 48-hour inflation of spiral inflation coil and local delivery of heparin.
Catheterization and cardiovascular diagnosis 1996;39(1):103-5.
1996: Michio Shimabukuro; Satoshi Higa; T Shinzato; F Nagamine; I Komiya; Nobuyuki Takasu
Cardioprotective effects of troglitazone in streptozotocin-induced diabetic rats.
Metabolism: clinical and experimental 1996;45(9):1168-73.
1996: T Shinzato; Michio Shimabukuro; Satoshi Higa; F Nagamine; K Murakami; Nobuyuki Takasu
Effect of gliclazide on the functional response to calcium in diabetic rat heart.
General pharmacology 1996;27(3):471-5.
1996: Michio Shimabukuro; T Shinzato; H Yoshida; F Nagamine; Nobuyuki Takasu; K Koja
Late complications in traumatic coronary artery fistula: report of a case requiring surgical repair after 8 years.
Cardiology 1996;87(1):86-9.
1996: Michio Shimabukuro; Satoshi Higa; T Shinzato; F Nagamine; Nobuyuki Takasu
Enhancement of postischemic myocardial stunning by calcium overload in hearts of diabetic rats.
Life sciences 1996;58(15):1291-9.
1995: Satoshi Higa; Michio Shimabukuro; T Shinzato; F Nagamine; K Murakami; Nobuyuki Takasu
Long-term nifedipine treatment reduces calcium overload in isolated reperfused hearts of diabetic rats.
General pharmacology 1995;26(8):1679-86.
1995: K Taniai; K Kadono-Okuda; Y Kato; M Yamamoto; Michio Shimabukuro; S Chowdhury; J Xu; Eiji Kotani; S Tomino; Minoru Yamakawa
Structure of two cecropin B-encoding genes and bacteria-inducible DNA-binding proteins which bind to the 5'-upstream regulatory region in the silkworm, Bombyx mori.
Gene 1995;163(2):215-9.
1995: Michio Shimabukuro; T Shinzato; Satoshi Higa; F Nagamine; K Murakami; Nobuyuki Takasu
Impaired mechanical response to calcium of diabetic rat hearts: reversal by nifedipine treatment.
Journal of cardiovascular pharmacology 1995;26(3):495-502.
1995: M Sugiyama; H Kuniyoshi; Eiji Kotani; K Taniai; K Kadono-Okuda; Y Kato; M Yamamoto; Michio Shimabukuro; S Chowdhury; J Xu
Characterization of a Bombyx mori cDNA encoding a novel member of the attacin family of insect antibacterial proteins.
Insect biochemistry and molecular biology 1995;25(3):385-92.
1995: Michio Shimabukuro; T Shinzato; Satoshi Higa; T Chibana; H Yoshida; F Nagamine; K Murakami; Nobuyuki Takasu
Enhanced insulin response relates to acetylcholine-induced vasoconstriction in vasospastic angina.
Journal of the American College of Cardiology 1995;25(2):356-61.
1994: Michio Shimabukuro; F Nagamine; K Murakami; K Oshiro; G Mimura
Chronic gliclazide treatment affects basal and post-ischemic cardiac function in diabetic rats.
General pharmacology 1994;25(4):697-704.
1994: Y Kato; Y Motoi; K Taniai; K Kadono-Okuda; M Yamamoto; Y Higashino; Michio Shimabukuro; S Chowdhury; J Xu; M Sugiyama
Lipopolysaccharide-lipophorin complex formation in insect hemolymph: a common pathway of lipopolysaccharide detoxification both in insects and in mammals.
Insect biochemistry and molecular biology 1994;24(6):547-55.
1992: Y Nakada; Y Machida; T Niisato; Michio Shimabukuro; M Ishimine; K Oshiro; F Nagamine; K Murakami; G Mimura
[A case of recurrent syncope due to pulmonary embolism].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 1992;81(8):1266-7.
1991: Y Nakada; M Simajiri; Michio Shimabukuro; K Oshiro; F Nagamine; K Murakami; G Mimura; Yuzo Koyama; A Osawa
[An elderly case of idiopathic retroperitoneal fibrosis].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 1991;28(6):811-6.
1991: T Chibana; F Nagamine; R Sunagawa; K Oshiro; Y Nakada; Michio Shimabukuro; T Shinzato; K Murakami; G Mimura; Matao Sakanashi
Comparison of the acute hemodynamic and coronary vasodilating effects between nicorandil and glyceryl trinitrate.
Arzneimittel-Forschung 1991;41(6):591-4.
1990: K Oshiro; Michio Shimabukuro; Y Nakada; T Chibana; H Yoshida; F Nagamine; R Sunagawa; M Gushiken; K Murakami; G Mimura
Multiple coronary LV fistulas: demonstration of coronary steal phenomenon by stress thallium scintigraphy and exercise hemodynamics.
American heart journal 1990;120(1):217-9.