Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Robert Colman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Anatomy

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

Physiology

Platelet Aggregation

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
33
DeLa Cadena, Raul
28
Pixley, Robin
27
Scott, CF
26
Colman, Roberta
23
Puri, RN
22
Isordia-Salas, Irma
18
Edmunds, Henry
16
Sainz, Irma
16
Sartor, Balfour
16
Niewiarowski, Stefan
16
Stadnicki, Antoni
15
Kunapuli, Satya
12
Schmaier, Alvin
10
Rao, Koneti
10
Khan, Mohammad

Sign-in to see all Coauthors

Publications

TOP 3
Liu Y; Pixley R; Fusaro M; Godoy G; Kim E; Bromberg M E; Colman R W
Cleaved high-molecular-weight kininogen and its domain 5 inhibit migration and invasion of human prostate cancer cells through the epidermal growth factor receptor pathway.
Liu Yuchuan; Cao Dian J; Sainz Irma M; Guo Yan-Lin; Colman Robert W
The inhibitory effect of HKa in endothelial cell tube formation is mediated by disrupting the uPA-uPAR complex and inhibiting its signaling and internalization.
Hung Su H; Liu Andy H; Pixley Robin A; Francis Penelope; Williams LaTeeka D; Matsko Christopher M; Barnes Karine D; Sivendran Sharmila; Colman Roberta F; Colman Robert W
A new nonhydrolyzable reactive cGMP analogue, (Rp)-guanosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate, which targets the cGMP binding site of human platelet PDE3A.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Robert Colman (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Liu Y; Pixley R; Fusaro M; Godoy G; Kim E; Bromberg M E; Colman R W
Cleaved high-molecular-weight kininogen and its domain 5 inhibit migration and invasion of human prostate cancer cells through the epidermal growth factor receptor pathway.
Oncogene 2009;28(30):2756-65.
2008: Liu Yuchuan; Cao Dian J; Sainz Irma M; Guo Yan-Lin; Colman Robert W
The inhibitory effect of HKa in endothelial cell tube formation is mediated by disrupting the uPA-uPAR complex and inhibiting its signaling and internalization.
American journal of physiology. Cell physiology 2008;295(1):C257-67.
2008: Hung Su H; Liu Andy H; Pixley Robin A; Francis Penelope; Williams LaTeeka D; Matsko Christopher M; Barnes Karine D; Sivendran Sharmila; Colman Roberta F; Colman Robert W
A new nonhydrolyzable reactive cGMP analogue, (Rp)-guanosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate, which targets the cGMP binding site of human platelet PDE3A.
Bioorganic chemistry 2008;36(3):141-7.
2008: Liu Yuchuan; Sainz Irma M; Wu Yi; Pixley Robin; Espinola Ricardo G; Hassan Sarmina; Khan Mohammad M; Colman Robert W
The inhibition of tube formation in a collagen-fibrinogen, three-dimensional gel by cleaved kininogen (HKa) and HK domain 5 (D5) is dependent on Src family kinases.
Experimental cell research 2008;314(4):774-88.
2007: Wu Yi; Rizzo Victor; Liu Yuchuan; Sainz Irma M; Schmuckler Noah G; Colman Robert W
Kininostatin associates with membrane rafts and inhibits alpha(v)beta3 integrin activation in human umbilical vein endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(9):1968-75.
2007: Zhang Wei; Colman Robert W
Thrombin regulates intracellular cyclic AMP concentration in human platelets through phosphorylation/activation of phosphodiesterase 3A.
Blood 2007;110(5):1475-82.
2007: Sainz Irma M; Pixley Robin A; Colman Robert W
Fifty years of research on the plasma kallikrein-kinin system: from protein structure and function to cell biology and in-vivo pathophysiology.
Thrombosis and haemostasis 2007;98(1):77-83.
2007: Hassan Sarmina; Sainz Irma M; Khan Mohammad M; Bradford Harlan N; Isordia-Salas Irma; Kashem Sakeen W; Sartor R Balfour; Colman Robert W
Antithrombotic activity of kininogen is mediated by inhibitory effects of domain 3 during arterial injury in vivo.
American journal of physiology. Heart and circulatory physiology 2007;292(6):H2959-65.
2007: Bior A D; Pixley R A; Colman R W
Domain 5 of kininogen inhibits proliferation of human colon cancer cell line (HCT-116) by interfering with G1/S in the cell cycle.
Journal of thrombosis and haemostasis : JTH 2007;5(2):403-11.
2006: Edmunds L Henry; Colman Robert W
Thrombin during cardiopulmonary bypass.
The Annals of thoracic surgery 2006;82(6):2315-22.
2006: Khan Mohammad M; Bradford Harlan N; Isordia-Salas Irma; Liu Yuchuan; Wu Yi; Espinola Ricardo G; Ghebrehiwet Berhane; Colman Robert W
High-molecular-weight kininogen fragments stimulate the secretion of cytokines and chemokines through uPAR, Mac-1, and gC1qR in monocytes.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2260-6.
2006: Hung Su-Hwi; Zhang Wei; Pixley Robin A; Jameson Bradford A; Huang Yu Chu; Colman Roberta F; Colman Robert W
New insights from the structure-function analysis of the catalytic region of human platelet phosphodiesterase 3A: a role for the unique 44-amino acid insert.
The Journal of biological chemistry 2006;281(39):29236-44.
2006: Sainz Irma M; Isordia-Salas Irma; Espinola Ricardo G; Long Walter K; Pixley Robin A; Colman Robert W
Multiple myeloma in a murine syngeneic model:modulation of growth and angiogenesis by a monoclonal antibody to kininogen.
Cancer immunology, immunotherapy : CII 2006;55(7):797-807.
2006: Colman Robert W
Are hemostasis and thrombosis two sides of the same coin?
The Journal of experimental medicine 2006;203(3):493-5.
2006: Khan Mohammad M H; Hattori Takashi; Niewiarowski Stefan; Edmunds L Henry; Colman Robert W
Truncated and microparticle-free soluble tissue factor bound to peripheral monocytes preferentially activate factor VII.
Thrombosis and haemostasis 2006;95(3):462-8.
2006: Colman Robert W
Regulation of angiogenesis by the kallikrein-kinin system.
Current pharmaceutical design 2006;12(21):2599-607.
2005: Isordia-Salas Irma; Sainz Irma M; Pixley Robin A; Martínez-Murillo Carlos; Colman Robert W
[High molecular weight kininogen in inflammation and angiogenesis: a review of its properties and therapeutic applications]
Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición 2005;57(6):802-13.
2005: Katkade Vaibhav; Soyombo Abigail A; Isordia-Salas Irma; Bradford Harlan N; Gaughan John P; Colman Robert W; Panetti Tracee S
Domain 5 of cleaved high molecular weight kininogen inhibits endothelial cell migration through Akt.
Thrombosis and haemostasis 2005;94(3):606-14.
2005: Devani M; Vecchi M; Ferrero S; Avesani E Contessini; Arizzi C; Chao L; Colman R W; Cugno M
Kallikrein-kinin system in inflammatory bowel diseases: Intestinal involvement and correlation with the degree of tissue inflammation.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2005;37(9):665-73.
2005: Hattori Takashi; Khan Mohammad M H; Colman Robert W; Edmunds L Henry
Plasma tissue factor plus activated peripheral mononuclear cells activate factors VII and X in cardiac surgical wounds.
Journal of the American College of Cardiology 2005;46(4):707-13.
2005: Sainz Irma M; Isordia-Salas Irma; Castaneda Julian L; Agelan Alexis; Liu Bo; DeLa Cadena Raul A; Pixley Robin A; Adam Albert; Sartor R Balfour; Colman Robert W
Modulation of inflammation by kininogen deficiency in a rat model of inflammatory arthritis.
Arthritis and rheumatism 2005;52(8):2549-52.
2005: Stadnicki Antoni; Pastucha Ezbieta; Nowaczyk Grazyna; Mazurek Urszula; Plewka Danuta; Machnik Grzegorz; Wilczok Tadeusz; Colman Robert W
Immunolocalization and expression of kinin B1R and B2R receptors in human inflammatory bowel disease.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(2):G361-6.
2005: Isordia-Salas Irma; Pixley Robin A; Sáinz Irma M; Martínez-Murillo Carlos; Colman Robert W
The role of plasma high molecular weight kininogen in experimental intestinal and systemic inflammation.
Archives of medical research 2005;36(1):87-95.
2005: Keith James C; Sainz Irma M; Isordia-Salas Irma; Pixley Robin A; Leathurby Yelena; Albert Leo M; Colman Robert W
A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat.
Arthritis research & therapy 2005;7(4):R769-76.
2004: Song James S; Sainz Irma M; Cosenza Stephen C; Isordia-Salas Irma; Bior Abdel; Bradford Harlan N; Guo Yan-Lin; Pixley Robin A; Reddy E Premkumar; Colman Robert W
Inhibition of tumor angiogenesis in vivo by a monoclonal antibody targeted to domain 5 of high molecular weight kininogen.
Blood 2004;104(7):2065-72.
2004: Isordia-Salas Irma; Pixley Robin A; Sáinz Irma M; Martínez-Murillo Carlos; Colman Robert W
The role of plasma high molecular weight kininogen in experimental intestinal and systemic inflammation.
Archives of medical research 2004;35(5):369-77.
2004: Espinola Ricardo G; Uknis Audrey; Sainz Irma M; Isordia-Salas Irma; Pixley Robin; DeLa Cadena Raul; Long Walter; Agelan Alexis; Gaughan John; Adam Albert; Colman Robert W
A monoclonal antibody to high-molecular weight kininogen is therapeutic in a rodent model of reactive arthritis.
The American journal of pathology 2004;165(3):969-76.
2004: Yang Baohua; Cao Dian J; Sainz Irma; Colman Robert W; Guo Yan-Lin
Different roles of ERK and p38 MAP kinases during tube formation from endothelial cells cultured in 3-dimensional collagen matrices.
Journal of cellular physiology 2004;200(3):360-9.
2004: Colman Robert W
Platelet cyclic adenosine monophosphate phosphodiesterases: targets for regulating platelet-related thrombosis.
Seminars in thrombosis and hemostasis 2004;30(4):451-60.
2004: Cao Dian J; Guo Yan-Lin; Colman Robert W
Urokinase-type plasminogen activator receptor is involved in mediating the apoptotic effect of cleaved high molecular weight kininogen in human endothelial cells.
Circulation research 2004;94(9):1227-34.
2004: Sainz I M; Uknis A B; Isordia-Salas I; Dela Cadena R A; Pixley R A; Colman R W
Interactions between bradykinin (BK) and cell adhesion molecule (CAM) expression in peptidoglycan-polysaccharide (PG-PS)-induced arthritis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(7):887-9.
2004: Colman Robert W
The contact system and angiogenesis: potential for therapeutic control of malignancy.
Seminars in thrombosis and hemostasis 2004;30(1):45-61.
2003: Chavakis Triantafyllos; Santoso Sentot; Clemetson Kenneth J; Sachs Ulrich J H; Isordia-Salas Irma; Pixley Robin A; Nawroth Peter P; Colman Robert W; Preissner Klaus T
High molecular weight kininogen regulates platelet-leukocyte interactions by bridging Mac-1 and glycoprotein Ib.
The Journal of biological chemistry 2003;278(46):45375-81.
2003: Isordia-Salas Irma; Pixley Robin A; Parekh Hemant; Kunapuli Satya P; Li Fengling; Stadnicki Anthony; Lin Yingzhang; Sartor R Balfour; Colman Robert W
The mutation Ser511Asn leads to N-glycosylation and increases the cleavage of high molecular weight kininogen in rats genetically susceptible to inflammation.
Blood 2003;102(8):2835-42.
2003: Pixley R A; Lin Y; Isordia-Salas I; Colman R W
Fine mapping of the sequences in domain 5 of high molecular weight kininogen (HK) interacting with heparin and zinc.
Journal of thrombosis and haemostasis : JTH 2003;1(8):1791-8.
2003: Rhee Joong-Sup; Santoso Sentot; Herrmann Mathias; Bierhaus Angelika; Kanse Sandip M; May Andreas E; Nawroth Peter P; Colman Robert W; Preissner Klaus T; Chavakis Triantafyllos
New aspects of integrin-mediated leukocyte adhesion in inflammation: regulation by haemostatic factors and bacterial products.
Current molecular medicine 2003;3(4):387-92.
2003: Guo Yan-Lin; Wang Shujie; Cao Dian J; Colman Robert W
Apoptotic effect of cleaved high molecular weight kininogen is regulated by extracellular matrix proteins.
Journal of cellular biochemistry 2003;89(3):622-32.
2003: Wang Shujie; Hasham Muneer G; Isordia-Salas Irma; Tsygankov Alexander Y; Colman Robert W; Guo Yan-Lin
Upregulation of Cdc2 and cyclin A during apoptosis of endothelial cells induced by cleaved high-molecular-weight kininogen.
American journal of physiology. Heart and circulatory physiology 2003;284(6):H1917-23.
2003: Stadnicki Antoni; Mazurek Urszula; Gonciarz Maciej; Plewka Danuta; Nowaczyk Grazyna; Orchel Joanna; Pastucha Ezbieta; Plewka Andrzej; Wilczok Tadcusz; Colman Robert W
Immunolocalization and expression of kallistatin and tissue kallikrein in human inflammatory bowel disease.
Digestive diseases and sciences 2003;48(3):615-23.
2003: Zhang H; Colman R W; Sheng N
Regulation of CD11b/CD18 (Mac-1) adhesion to fibrinogen by urokinase receptor (uPAR).
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52(2):86-93.
2003: Colman R W; Pixley R A; Sainz I M; Song J S; Isordia-Salas I; Muhamed S N; Powell J A; Mousa S A
Inhibition of angiogenesis by antibody blocking the action of proangiogenic high-molecular-weight kininogen.
Journal of thrombosis and haemostasis : JTH 2003;1(1):164-70.
2003: Stadnicki Antoni; Colman Robert W
Experimental models of inflammatory bowel disease.
Archivum immunologiae et therapiae experimentalis 2003;51(3):149-55.
2002: Guo Yan-Lin; Wang Shujie; Colman Robert W
Kininostatin as an antiangiogenic inhibitor: what we know and what we do not know.
International immunopharmacology 2002;2(13-14):1931-40.
2002: Isordia-Salas Irma; Pixley Robin A; Li Fengling; Sainz Irma; Balfour Sartor R; Adam Albert; Colman Robert W
Chronic intestinal inflammation and angiogenesis in genetically susceptible rats is modulated by kininogen deficiency.
International immunopharmacology 2002;2(13-14):1895-905.
2002: Colman Robert W
Inhibition of angiogenesis by a monoclonal antibody to kininogen as well as by kininostatin which block proangiogenic high molecular weight kininogen.
International immunopharmacology 2002;2(13-14):1887-94.
2002: Zhang W; Ke H; Colman R W
Identification of interaction sites of cyclic nucleotide phosphodiesterase type 3A with milrinone and cilostazol using molecular modeling and site-directed mutagenesis.
Molecular pharmacology 2002;62(3):514-20.
2002: Chavakis Triantafyllos; Pixley Robin A; Isordia-Salas Irma; Colman Robert W; Preissner Klaus T
A novel antithrombotic role for high molecular weight kininogen as inhibitor of plasminogen activator inhibitor-1 function.
The Journal of biological chemistry 2002;277(36):32677-82.
2002: Devani Massimo; Cugno Massimo; Vecchi Maurizio; Ferrero Stefano; Di Berardino Federica; Avesani Ettore Contessini; de Franchis Roberto; Colman Robert W
Kallikrein-kinin system activation in Crohn's disease: differences in intestinal and systemic markers.
The American journal of gastroenterology 2002;97(8):2026-32.
2002: Isordia-Salas Irma; Pixley Robin A; Li Fengling; Sainz Irma; Sartor R Balfour; Adam Albert; Colman Robert W
Kininogen deficiency modulates chronic intestinal inflammation in genetically susceptible rats.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(1):G180-6.
2002: Chavakis Triantafyllos; Boeckel Nicole; Santoso Sentot; Voss Reinhard; Isordia-Salas Irma; Pixley Robin A; Morgenstern Eberhard; Colman Robert W; Preissner Klaus T
Inhibition of platelet adhesion and aggregation by a defined region (Gly-486-Lys-502) of high molecular weight kininogen.
The Journal of biological chemistry 2002;277(26):23157-64.
2002: Manns J M; Brenna K J; Colman R W; Sheth S B
Differential regulation of human platelet responses by cGMP inhibited and stimulated cAMP phosphodiesterases.
Thrombosis and haemostasis 2002;87(5):873-9.
2002: Hung Su H; Madhusoodanan K S; Boyd Robert L; Baldwin James L; Colman Roberta F; Colman Robert W
A nonhydrolyzable reactive cAMP analogue, (S(p))-8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 3',5'-cyclic S-(methyl)monophosphorothioate, irreversibly inactivates human platelet cGMP-inhibited cAMP phosphodiesterase at micromolar concentrations.
Biochemistry 2002;41(9):2962-9.
2002: Hung Su H; Madhusoodanan K S; Beres James A; Boyd Robert L; Baldwin James L; Zhang Wei; Colman Robert W; Colman Roberta F
A new nonhydrolyzable reactive cAMP analog, (Sp)-adenosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate irreversibly inactivates human platelet cGMP-inhibited cAMP phosphodiesterase.
Bioorganic chemistry 2002;30(1):16-31.
2001: Chavakis T; Kanse S M; Pixley R A; May A E; Isordia-Salas I; Colman R W; Preissner K T
Regulation of leukocyte recruitment by polypeptides derived from high molecular weight kininogen.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(13):2365-76.
2001: Guo Y L; Wang S; Colman R W
Kininostatin, an angiogenic inhibitor, inhibits proliferation and induces apoptosis of human endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(9):1427-33.
2001: Zhang W; Ke H; Tretiakova A P; Jameson B; Colman R W
Identification of overlapping but distinct cAMP and cGMP interaction sites with cyclic nucleotide phosphodiesterase 3A by site-directed mutagenesis and molecular modeling based on crystalline PDE4B.
Protein science : a publication of the Protein Society 2001;10(8):1481-9.
2001: Uknis A B; DeLa Cadena R A; Janardham R; Sartor R B; Whalley E T; Colman R W
Bradykinin receptor antagonists type 2 attenuate the inflammatory changes in peptidoglycan-induced acute arthritis in the Lewis rat.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2001;50(3):149-55.
2001: Colman R W
Role of the light chain of high molecular weight kininogen in adhesion, cell-associated proteolysis and angiogenesis.
Biological chemistry 2001;382(1):65-70.
2001: Selim T E; Ghoneim H R; Abdel Ghaffar H A; Colman R W; Dela Cadena R A
High molecular mass kininogen inhibits cathepsin G-induced platelet activation by forming a complex with cathepsin G.
The hematology journal : the official journal of the European Haematology Association / EHA 2001;2(6):371-7.
2000: Majluf-Cruz A; Manns J M; Uknis A B; Yang X; Colman R W; Harris R B; Frazier W; Lawler J; DeLa Cadena R A
Residues F16-G33 and A784-N823 within platelet thrombospondin-1 play a major role in binding human neutrophils: evaluation by two novel binding assays.
The Journal of laboratory and clinical medicine 2000;136(4):292-302.
2000: Chavakis T; Kanse S M; Lupu F; Hammes H P; Müller-Esterl W; Pixley R A; Colman R W; Preissner K T
Different mechanisms define the antiadhesive function of high molecular weight kininogen in integrin- and urokinase receptor-dependent interactions.
Blood 2000;96(2):514-22.
2000: Bradford H N; Pixley R A; Colman R W
Human factor XII binding to the glycoprotein Ib-IX-V complex inhibits thrombin-induced platelet aggregation.
The Journal of biological chemistry 2000;275(30):22756-63.
2000: Sheng N; Fairbanks M B; Heinrikson R L; Canziani G; Chaiken I M; Mosser D M; Zhang H; Colman R W
Cleaved high molecular weight kininogen binds directly to the integrin CD11b/CD18 (Mac-1) and blocks adhesion to fibrinogen and ICAM-1.
Blood 2000;95(12):3788-95.
2000: Mseeh F; Colman R F; Colman R W
Inactivation of platelet PDE2 by an affinity label: 8-[(4-bromo-2, 3-dioxobutyl)thio]cAMP.
Thrombosis research 2000;98(5):395-401.
2000: Zhang W; Colman R W
Conserved amino acids in metal-binding motifs of PDE3A are involved in substrate and inhibitor binding.
Blood 2000;95(11):3380-6.
2000: Lin Y; Pixley R A; Colman R W
Kinetic analysis of the role of zinc in the interaction of domain 5 of high-molecular weight kininogen (HK) with heparin.
Biochemistry 2000;39(17):5104-10.
2000: Yung L Y; Lim F; Khan M M; Kunapuli S P; Rick L; Colman R W; Cooper S L
High-molecular-weight kininogen preadsorbed to glass surface markedly reduces neutrophil adhesion.
Biomaterials 2000;21(4):405-14.
2000: Colman R W; Jameson B A; Lin Y; Johnson D; Mousa S A
Domain 5 of high molecular weight kininogen (kininostatin) down-regulates endothelial cell proliferation and migration and inhibits angiogenesis.
Blood 2000;95(2):543-50.
1999: Colman R W
Biologic activities of the contact factors in vivo--potentiation of hypotension, inflammation, and fibrinolysis, and inhibition of cell adhesion, angiogenesis and thrombosis.
Thrombosis and haemostasis 1999;82(6):1568-77.
1999: Cugno M; Scott C F; Salerno F; Lorenzano E; Müller-Esterl W; Agostoni A; Colman R W
Parallel reduction of plasma levels of high and low molecular weight kininogen in patients with cirrhosis.
Thrombosis and haemostasis 1999;82(5):1428-32.
1999: Yung L Y; Colman R W; Cooper S L
Neutrophil adhesion on polyurethanes preadsorbed with high molecular weight kininogen.
Blood 1999;94(8):2716-24.
1999: Yung L Y; Colman R W; Cooper S L
The effect of high molecular weight kininogen on neutrophil adhesion to polymer surfaces.
Immunopharmacology 1999;43(2-3):281-6.
1999: Colman R W
Plasma and tissue kallikrein in arthritis and inflammatory bowel disease.
Immunopharmacology 1999;43(2-3):103-8.
1999: Colman R W; White J V; Scovell S; Stadnicki A; Sartor R B
Kininogens are antithrombotic proteins In vivo.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(9):2245-50.
1999: Khan M M; Gikakis N; Miyamoto S; Rao A K; Cooper S L; Edmunds L H; Colman R W
Aprotinin inhibits thrombin formation and monocyte tissue factor in simulated cardiopulmonary bypass.
The Annals of thoracic surgery 1999;68(2):473-8.
1998: Gikakis N; Rao A K; Miyamoto S; Gorman J H; Khan M M; Anderson H L; Hack C E; Sun L; Niewiarowski S; Colman R W; Edmunds L H
Enoxaparin suppresses thrombin formation and activity during cardiopulmonary bypass in baboons.
The Journal of thoracic and cardiovascular surgery 1998;116(6):1043-51.
1998: Cheung P P; Yu L; Zhang H; Colman R W
Partial characterization of the active site human platelet cAMP phosphodiesterase, PDE3A, by site-directed mutagenesis.
Archives of biochemistry and biophysics 1998;360(1):99-104.
1998: Wachtfogel Y T; Kettner C; Hack C E; Nuijens J H; Reilly T M; Knabb R M; Kucich U; Niewiarowski S; Edmunds L H; Colman R W
Thrombin and human plasma kallikrein inhibition during simulated extracorporeal circulation block platelet and neutrophil activation.
Thrombosis and haemostasis 1998;80(4):686-91.
1998: Stadnicki A; Chao J; Stadnicka I; Van Tol E; Lin K F; Li F; Sartor R B; Colman R W
Localization and secretion of tissue kallikrein in peptidoglycan-induced enterocolitis in Lewis rats.
The American journal of physiology 1998;275(4 Pt 1):G854-61.
1998: Stadnicki A; Sartor R B; Janardham R; Stadnicka I; Adam A A; Blais C; Colman R W
Kallikrein-kininogen system activation and bradykinin (B2) receptors in indomethacin induced enterocolitis in genetically susceptible Lewis rats.
Gut 1998;43(3):365-74.
1998: Omburo G A; Jacobitz S; Torphy T J; Colman R W
Critical role of conserved histidine pairs HNXXH and HDXXH in recombinant human phosphodiesterase 4A.
Cellular signalling 1998;10(7):491-7.
1998: Puri R N; Colman R W
Purinergic receptors in human blood platelets: chemical modification and cloning investigations.
Journal of protein chemistry 1998;17(5):429-51.
1998: Khan M M; Kunapuli S P; Lin Y; Majluf-Cruz A; Cadena R A; Cooper S L; Colman R W
Three noncontiguous peptides comprise binding sites on high-molecular-weight kininogen to neutrophils.
The American journal of physiology 1998;275(1 Pt 2):H145-50.
1998: DeLa Cadena R A; Majluf-Cruz A; Stadnicki A; Tropea M; Reda D; Agosti J M; Colman R W; Suffredini A F
Recombinant tumor necrosis factor receptor p75 fusion protein (TNFR:Fc) alters endotoxin-induced activation of the kinin, fibrinolytic, and coagulation systems in normal humans.
Thrombosis and haemostasis 1998;80(1):114-8.
1998: Scott C F; Brandwein H; Whitbread J; Colman R W
Lack of clinically significant contact system activation during platelet concentrate filtration by leukocyte removal filters.
Blood 1998;92(2):616-22.
1998: Lin Y; Li W; Wu J; Zhang H; Colman R W
Fourier transform infrared (FT-IR) spectroscopic studies of peptide models for interaction of the binding regions of high molecular weight kininogen and prekallikrein.
Thrombosis research 1998;90(2):65-72.
1998: Stadnicki A; Sartor R B; Janardham R; Majluf-Cruz A; Kettner C A; Adam A A; Colman R W
Specific inhibition of plasma kallikrein modulates chronic granulomatous intestinal and systemic inflammation in genetically susceptible rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(3):325-33.
1998: DeLa Cadena R A; Kunapuli S P; Walz D A; Colman R W
Expression of thrombospondin 1 on the surface of activated platelets mediates their interaction with the heavy chains of human kininogens through Lys 244-Pro 254.
Thrombosis and haemostasis 1998;79(1):186-94.
1998: Colman R W; Sartor R B; Adam A A; DeLa Cadena R A; Stadnicki A
The plasma kallikrein-kinin system in sepsis, inflammatory arthritis, and enterocolitis.
Clinical reviews in allergy & immunology 1998;16(4):365-84.
1997: Sheth S B; Chaganti K; Bastepe M; Ajuria J; Brennan K; Biradavolu R; Colman R W
Cyclic AMP phosphodiesterases in human lymphocytes.
British journal of haematology 1997;99(4):784-9.
1997: Selim T E; Ghoneim H R; Uknis A B; Colman R W; DeLa Cadena R A
High-molecular-mass and low-molecular-mass kininogens block plasmin-induced platelet aggregation by forming a complex with kringle 5 of plasminogen/plasmin.
European journal of biochemistry / FEBS 1997;250(2):532-8.
1997: Stadnicki A; Gonciarz M; Niewiarowski T J; Hartleb J; Rudnicki M; Merrell N B; Dela Cadena R A; Colman R W
Activation of plasma contact and coagulation systems and neutrophils in the active phase of ulcerative colitis.
Digestive diseases and sciences 1997;42(11):2356-66.
1997: Puri R N; Colman R W
Immunoaffinity method to identify aggregin, a putative ADP-receptor in human blood platelets.
Archives of biochemistry and biophysics 1997;347(2):263-70.
1997: Colman R W; Schmaier A H
Contact system: a vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes.
Blood 1997;90(10):3819-43.
1997: Hiramatsu Y; Gikakis N; Gorman J H; Khan M M; Hack C E; Velthuis H T; Sun L; Marcinkiewicz C; Rao A K; Niewiarowski S; Colman R W; Edmunds L H; Anderson H L
A baboon model for hematologic studies of cardiopulmonary bypass.
The Journal of laboratory and clinical medicine 1997;130(4):412-20.
1997: Colman R W; Pixley R A; Najamunnisa S; Yan W; Wang J; Mazar A; McCrae K R
Binding of high molecular weight kininogen to human endothelial cells is mediated via a site within domains 2 and 3 of the urokinase receptor.
The Journal of clinical investigation 1997;100(6):1481-7.
1997: Bradford H N; Dela Cadena R A; Kunapuli S P; Dong J F; Löpez J A; Colman R W
Human kininogens regulate thrombin binding to platelets through the glycoprotein Ib-IX-V complex.
Blood 1997;90(4):1508-15.
1997: Lin Y; Harris R B; Yan W; McCrae K R; Zhang H; Colman R W
High molecular weight kininogen peptides inhibit the formation of kallikrein on endothelial cell surfaces and subsequent urokinase-dependent plasmin formation.
Blood 1997;90(2):690-7.
1997: Puri R N; Colman R F; Colman R W
Modulation of platelet responses by 2-[3-(bromo-2-oxopropylthio)]adenosine-5'-diphosphate involves its binding to as well as covalent modification of an ADP-receptor, aggregin.
Archives of biochemistry and biophysics 1997;343(1):140-5.
1997: Colman R W; Lin Y; Yan W Y; McCrae K R; Shenoy S S; Harris R B
Physical and biological significance of peptide sequences mediating the interaction between high molecular weight kininogen and plasma prekallikrein.
Immunopharmacology 1997;36(2-3):193-200.
1997: Omburo G A; Torphy T J; Scott G; Jacobitz S; Colman R F; Colman R W
Inactivation of recombinant monocyte cAMP-specific phosphodiesterase by cAMP analog, 8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 3',5'-cyclic monophosphate.
Blood 1997;89(3):1019-26.
1997: Sheth S B; Brennan K J; Biradavolu R; Colman R W
Isolation and regulation of the cGMP-inhibited cAMP phosphodiesterase in human erythroleukemia cells.
Thrombosis and haemostasis 1997;77(1):155-62.
1997: Scott C F; Shull B; Müller-Esterl W; Colman R W
Rapid direct determination of low and high molecular weight kininogen in human plasma by Particle Concentration Fluorescence Immunoassay (PCFIA).
Thrombosis and haemostasis 1997;77(1):109-18.
1997: Colman R W; Stadnicki A; Kettner C A; Adam A A; DeLa Cadena R A; Sartor R B
Activation of the kallikrein-kinin system in arthritis and enterocolitis in genetically susceptible rats: modulation by a selective plasma kallikrein inhibitor.
Proceedings of the Association of American Physicians 1997;109(1):10-22.
1997: Puri R N; Colman R W
ADP-induced platelet activation.
Critical reviews in biochemistry and molecular biology 1997;32(6):437-502.
1996: Gikakis N; Khan M M; Hiramatsu Y; Gorman J H; Hack C E; Sun L; Rao A K; Niewiarowski S; Colman R W; Edmunds L H
Effect of factor Xa inhibitors on thrombin formation and complement and neutrophil activation during in vitro extracorporeal circulation.
Circulation 1996;94(9 Suppl):II341-6.
1996: Colman R W; Scott C F; Brandwein H; Whitbread J
More on kininogen measurements in platelet concentrates that are white cell (WBC) reduced with WBC-reduction filters.
Transfusion 1996;36(10):939-41.
1996: Lin Y; Shenoy S S; Harris R B; Colman R W
Direct evidence for multifacial contacts between high molecular weight kininogen and plasma prekallikrein.
Biochemistry 1996;35(39):12945-9.
1996: Puri R N; Colman R W
A novel method for chemical modification of functional groups other than a carboxyl group in proteins by N-ethyl-5-phenylisooxazolium-3'-sulfonate (Woodward's reagent-K): inhibition of ADP-induced platelet responses involves covalent modification of aggregin, an ADP receptor.
Analytical biochemistry 1996;240(2):251-61.
1996: Bano B; Kunapuli S P; Bradford H N; Colman R W
Structural requirements for cathepsin B and cathepsin H inhibition by kininogens.
Journal of protein chemistry 1996;15(6):519-25.
1996: Cheung P P; Xu H; McLaughlin M M; Ghazaleh F A; Livi G P; Colman R W
Human platelet cGI-PDE: expression in yeast and localization of the catalytic domain by deletion mutagenesis.
Blood 1996;88(4):1321-9.
1996: Ghazaleh F A; Omburo G A; Colman R W
Evidence for the presence of essential histidine and cysteine residues in platelet cGMP-inhibited phosphodiesterase.
The Biochemical journal 1996;317 ( Pt 2)():495-501.
1996: Rothschild A M; Boden G; Colman R W
Kininogen changes in human plasma following a test meal or insulin administration.
Immunopharmacology 1996;33(1-3):354-8.
1996: Stadnicki A; DeLa Cadena R A; Sartor R B; Kettner C A; Colman R W
The contact system in experimental enterocolitis.
Immunopharmacology 1996;33(1-3):314-6.
1996: DeLa Cadena R A; Majluf-Cruz A; Stadnicki A; Agosti J M; Colman R W; Suffredini A F
Activation of the contact and fibrinolytic systems after intravenous administration of endotoxin to normal human volunteers: correlation with the cytokine profile.
Immunopharmacology 1996;33(1-3):231-7.
1996: Chung J H; Gikakis N; Rao A K; Drake T A; Colman R W; Edmunds L H
Pericardial blood activates the extrinsic coagulation pathway during clinical cardiopulmonary bypass.
Circulation 1996;93(11):2014-8.
1996: Colman R W; Bradford H N; Kunapuli S P; DeLa Cadena R A; Rick L; Jameson B A; Wassell R P
Leu271-Glu292 in kininogens blocks thrombin-induced aggregation.
Immunopharmacology 1996;32(1-3):80-1.
1996: Yung L Y; Lim F; Khan M M; Kunapuli S P; Rick L; Colman R W; Cooper S L
Neutrophil adhesion on surfaces preadsorbed with high molecular weight kininogen under well-defined flow conditions.
Immunopharmacology 1996;32(1-3):19-23.
1996: Colman R W
Inhibitory and antiadhesive properties of human kininogens.
Immunopharmacology 1996;32(1-3):9-18.
1996: Sundaram S; Lim F; Cooper S L; Colman R W
Role of leucocytes in coagulation induced by artificial surfaces: investigation of expression of Mac-1, granulocyte elastase release and leucocyte adhesion on modified polyurethanes.
Biomaterials 1996;17(10):1041-7.
1996: Kunapuli S P; Bradford H N; Jameson B A; DeLa Cadena R A; Rick L; Wassell R P; Colman R W
Thrombin-induced platelet aggregation is inhibited by the heptapeptide Leu271-Ala277 of domain 3 in the heavy chain of high molecular weight kininogen.
The Journal of biological chemistry 1996;271(19):11228-35.
1996: Stadnicki A; DeLa Cadena R A; Sartor R B; Bender D; Kettner C A; Rath H C; Adam A; Colman R W
Selective plasma kallikrein inhibitor attenuates acute intestinal inflammation in Lewis rat.
Digestive diseases and sciences 1996;41(5):912-20.
1996: Puri R N; Colman R W
Inhibition of ADP-induced platelet activation by 7-chloro-4-nitrobenz-2-oxa-1,3-diazole: covalent modification of aggregin, a putative ADP receptor.
Journal of cellular biochemistry 1996;61(1):97-108.
1996: Puri R N; Colman R F; Colman R W
Platelet activation by 2-(4-bromo-2,3-dioxobutylthio)adenosine 5'-diphosphate is mediated by its binding to a putative ADP receptor, aggregin.
European journal of biochemistry / FEBS 1996;236(3):862-70.
1996: Sundaram S; Gikakis N; Hack C E; Niewiarowski S; Edmunds L H; Koneti Rao A; Sun L; Cooper S L; Colman R W
Nafamostat mesilate, a broad spectrum protease inhibitor, modulates platelet, neutrophil and contact activation in simulated extracorporeal circulation.
Thrombosis and haemostasis 1996;75(1):76-82.
1996: Gorman R C; Ziats N; Rao A K; Gikakis N; Sun L; Khan M M; Stenach N; Sapatnekar S; Chouhan V; Gorman J H; Niewiarowski S; Colman R W; Anderson J M; Edmunds L H
Surface-bound heparin fails to reduce thrombin formation during clinical cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 1996;111(1):1-11; discussion 11-2.
1995: Wyshock E G; Suffredini A F; Parrillo J E; Colman R W
Cofactors V and VIII after endotoxin administration to human volunteers.
Thrombosis research 1995;80(5):377-89.
1995: Puri R N; Kumar A; Chen H; Colman R F; Colman R W
Inhibition of ADP-induced platelet responses by covalent modification of aggregin, a putative ADP receptor, by 8-(4-bromo-2,3-dioxobutylthio)ADP.
The Journal of biological chemistry 1995;270(41):24482-8.
1995: Omburo G A; Brickus T; Ghazaleh F A; Colman R W
Divalent metal cation requirement and possible classification of cGMP-inhibited phosphodiesterase as a metallohydrolase.
Archives of biochemistry and biophysics 1995;323(1):1-5.
1995: Kunapuli S P; Stark P; Rick L; Colman R W
Determination of gene structure by intron trapping using polymerase chain reaction: application to the human plasma prekallikrein gene.
DNA and cell biology 1995;14(4):343-7.
1995: Sheth S B; Colman R W
Regulatory and catalytic domains of platelet cAMP phosphodiesterases: targets for drug design.
Seminars in hematology 1995;32(2):110-9.
1995: Colman R W
Hemostatic complications of cardiopulmonary bypass.
American journal of hematology 1995;48(4):267-72.
1995: Dela Cadena R A; Stadnicki A; Uknis A B; Sartor R B; Kettner C A; Adam A; Colman R W
Inhibition of plasma kallikrein prevents peptidoglycan-induced arthritis in the Lewis rat.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(5):446-52.
1995: Pixley R A; Zellis S; Bankes P; DeLa Cadena R A; Page J D; Scott C F; Kappelmayer J; Wyshock E G; Kelly J J; Colman R W
Prognostic value of assessing contact system activation and factor V in systemic inflammatory response syndrome.
Critical care medicine 1995;23(1):41-51.
1994: Wyshock E G; Stewart G J; Colman R W
Thrombin-stimulated human platelets express molecular forms of alpha-granule factor V (FV), which differ from FVa.
Thrombosis and haemostasis 1994;72(6):947-56.
1994: Wachtfogel Y T; Bischoff R; Bauer R; Hack C E; Nuijens J H; Kucich U; Niewiarowski S; Edmunds L H; Colman R W
Alpha 1-antitrypsin Pittsburgh (Met358-->Arg) inhibits the contact pathway of intrinsic coagulation and alters the release of human neutrophil elastase during simulated extracorporeal circulation.
Thrombosis and haemostasis 1994;72(6):843-7.
1994: Page J D; You J L; Harris R B; Colman R W
Localization of the binding site on plasma kallikrein for high-molecular-weight kininogen to both apple 1 and apple 4 domains of the heavy chain.
Archives of biochemistry and biophysics 1994;314(1):159-64.
1994: Colman R W
Significance of the regulation of plasma kallikrein by alpha 2M.
Annals of the New York Academy of Sciences 1994;737():347-67.
1994: Colman R W
Structure-function correlates of human high molecular weight kininogen.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(8):1839-53.
1994: Wachtfogel Y T; DeLa Cadena R A; Kunapuli S P; Rick L; Miller M; Schultze R L; Altieri D C; Edgington T S; Colman R W
High molecular weight kininogen binds to Mac-1 on neutrophils by its heavy chain (domain 3) and its light chain (domain 5).
The Journal of biological chemistry 1994;269(30):19307-12.
1994: DeLa Cadena R A; Wyshock E G; Kunapuli S P; Schultze R L; Miller M; Walz D A; Colman R W
Platelet thrombospondin interactions with human high and low molecular weight kininogens.
Thrombosis and haemostasis 1994;72(1):125-31.
1994: Page J D; DeLa Cadena R A; Humphries J E; Colman R W
An autoantibody to human plasma prekallikrein blocks activation of the contact system.
British journal of haematology 1994;87(1):81-6.
1994: Weisel J W; Nagaswami C; Woodhead J L; DeLa Cadena R A; Page J D; Colman R W
The shape of high molecular weight kininogen. Organization into structural domains, changes with activation, and interactions with prekallikrein, as determined by electron microscopy.
The Journal of biological chemistry 1994;269(13):10100-6.
1994: Matsueda R; Umeyama H; Puri R N; Bradford H N; Colman R W
Design and synthesis of a kininogen-based selective inhibitor of thrombin-induced platelet aggregation.
Peptide research 1994;7(1):32-5.
1994: Colman R W
The contact system and sepsis.
Progress in clinical and biological research 1994;388():195-214.
1993: Bradford H N; Jameson B A; Adam A A; Wassell R P; Colman R W
Contiguous binding and inhibitory sites on kininogens required for the inhibition of platelet calpain.
The Journal of biological chemistry 1993;268(35):26546-51.
1993: Colman R W; Rao A K; Rubin R N
Refractory thrombocytopenia in a 27-year-old female following allogeneic bone marrow transplantation.
American journal of hematology 1993;44(4):284-8.
1993: Puri R N; Matsueda R; Umeyama H; Colman R W
Specificity of the sequence in Phe-Gln-Val-Val-Cys (-3-nitro-2-pyridinesulfenyl)-Gly-NH2--a selective inhibitor of thrombin-induced platelet aggregation.
Thrombosis research 1993;72(3):183-91.
1993: Cheung P P; Kunapuli S P; Scott C F; Wachtfogel Y T; Colman R W
Genetic basis of total kininogen deficiency in Williams' trait.
The Journal of biological chemistry 1993;268(31):23361-5.
1993: Colman R W; Rao A K; Rubin R N
Platelet bleeding disorder in a 30-year-old female. Mechanisms of congenital platelet function defects.
American journal of hematology 1993;44(2):139-44.
1993: Wachtfogel Y T; DeLa Cadena R A; Colman R W
Structural biology, cellular interactions and pathophysiology of the contact system.
Thrombosis research 1993;72(1):1-21.
1993: You J L; Page J D; Scarsdale J N; Colman R W; Harris R B
Conformational analysis of synthetic peptides encompassing the factor XI and prekallikrein overlapping binding domains of high molecular weight kininogen.
Peptides 1993;14(5):867-76.
1993: Colman R W; Rao A K; Rubin R N
Warfarin skin necrosis in a 33-year-old woman.
American journal of hematology 1993;43(4):300-3.
1993: Kappelmayer J; Kunapuli S P; Wyshock E G; Colman R W
Characterization of monocyte-associated factor V.
Thrombosis and haemostasis 1993;70(2):273-80.
1993: Wachtfogel Y T; Kucich U; Hack C E; Gluszko P; Niewiarowski S; Colman R W; Edmunds L H
Aprotinin inhibits the contact, neutrophil, and platelet activation systems during simulated extracorporeal perfusion.
The Journal of thoracic and cardiovascular surgery 1993;106(1):1-9; discussion 9-10.
1993: Puri R N; Colman R W
Reocclusion after thrombolytic therapy: strategies for inhibiting thrombin-induced platelet aggregation.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1993;4(3):465-78.
1993: DeLa Cadena R A; Suffredini A F; Page J D; Pixley R A; Kaufman N; Parrillo J E; Colman R W
Activation of the kallikrein-kinin system after endotoxin administration to normal human volunteers.
Blood 1993;81(12):3313-7.
1993: Puri R N; Matsueda R; Umeyama H; Bradford H N; Colman R W
Modulation of thrombin-induced platelet aggregation by inhibition of calpain by a synthetic peptide derived from the thiol-protease inhibitory sequence of kininogens and S-(3-nitro-2-pyridinesulfenyl)-cysteine.
European journal of biochemistry / FEBS 1993;214(1):233-41.
1993: Kappelmayer J; Bernabei A; Edmunds L H; Edgington T S; Colman R W
Tissue factor is expressed on monocytes during simulated extracorporeal circulation.
Circulation research 1993;72(5):1075-81.
1993: Scott C F; Whitaker E J; Hammond B F; Colman R W
Purification and characterization of a potent 70-kDa thiol lysyl-proteinase (Lys-gingivain) from Porphyromonas gingivalis that cleaves kininogens and fibrinogen.
The Journal of biological chemistry 1993;268(11):7935-42.
1993: Puri R N; Colman R W
Thrombin- and cathepsin G-induced platelet aggregation: effect of protein kinase C inhibitors.
Analytical biochemistry 1993;210(1):50-7.
1993: Kunapuli S P; Colman R W
Two new phagemid vectors for site-directed mutagenesis and expression in E. coli.
BioTechniques 1993;14(3):332, 336-8.
1993: Kunapuli S P; DeLa Cadena R A; Colman R W
Deletion mutagenesis of high molecular weight kininogen light chain. Identification of two anionic surface binding subdomains.
The Journal of biological chemistry 1993;268(4):2486-92.
1993: Kappelmayer J; Bernabei A; Gikakis N; Edmunds L H; Colman R W
Upregulation of Mac-1 surface expression on neutrophils during simulated extracorporeal circulation.
The Journal of laboratory and clinical medicine 1993;121(1):118-26.
1993: Pixley R A; De La Cadena R; Page J D; Kaufman N; Wyshock E G; Chang A; Taylor F B; Colman R W
The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons.
The Journal of clinical investigation 1993;91(1):61-8.
1993: Pixley R A; Colman R W
Factor XII: Hageman factor.
Methods in enzymology 1993;222():51-65.
1993: Colman R W
Factor XII activation and inhibition in inflammation.
Agents and actions. Supplements 1993;42():125-43.
1992: Scott C F; Colman R W
Fibrinogen blocks the autoactivation and thrombin-mediated activation of factor XI on dextran sulfate.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11189-93.
1992: Rubin R N; Colman R W
Disseminated intravascular coagulation. Approach to treatment.
Drugs 1992;44(6):963-71.
1992: Gewirtz A M; Shapiro C; Shen Y M; Boyd R; Colman R W
Cellular and molecular regulation of factor V expression in human megakaryocytes.
Journal of cellular physiology 1992;153(2):277-87.
1992: Kunapuli S P; DeLa Cadena R A; Colman R W
Bacterial expression of biologically active high molecular weight kininogen light chain.
Thrombosis and haemostasis 1992;67(4):428-33.
1992: Mills D C; Puri R; Hu C J; Minniti C; Grana G; Freedman M D; Colman R F; Colman R W
Clopidogrel inhibits the binding of ADP analogues to the receptor mediating inhibition of platelet adenylate cyclase.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1992;12(4):430-6.
1992: Pixley R A; DeLa Cadena R A; Page J D; Kaufman N; Wyshock E G; Colman R W; Chang A; Taylor F B
Activation of the contact system in lethal hypotensive bacteremia in a baboon model.
The American journal of pathology 1992;140(4):897-906.
1992: Puri R N; Hu C J; Matsueda R; Umeyama H; Colman R W
Aggregation of washed platelets by plasminogen and plasminogen activators is mediated by plasmin and is inhibited by a synthetic peptide disulfide.
Thrombosis research 1992;65(4-5):533-47.
1992: Scott C F; Colman R W
Sensitive antigenic determinations of high molecular weight kininogen performed by covalent coupling of capture antibody.
The Journal of laboratory and clinical medicine 1992;119(1):77-86.
1992: DeLa Cadena R A; Colman R W
The sequence HGLGHGHEQQHGLGHGH in the light chain of high molecular weight kininogen serves as a primary structural feature for zinc-dependent binding to an anionic surface.
Protein science : a publication of the Protein Society 1992;1(1):151-60.
1992: Cheung P P; Cannizzaro L A; Colman R W
Chromosomal mapping of human kininogen gene (KNG) to 3q26----qter.
Cytogenetics and cell genetics 1992;59(1):24-6.
1992: Figures W R; Scearce L M; Colman R F; Colman R W
Interaction of nucleotide affinity analog 5'-p-fluorosulfonylbenzoyladenosine with platelet ADP receptor: aggregin.
Methods in enzymology 1992;215():143-55.
1992: Grant P G; DeCamp D L; Bailey J M; Colman R F; Colman R W
Low-Km cyclic AMP phosphodiesterase from human platelets. Stimulation of activity by phosphorylation of the enzyme and affinity labeling of the active site.
Advances in second messenger and phosphoprotein research 1992;25():73-85.
1992: DeLa Cadena R A; Sartor R B; Adam A; Raymond B; Legris F; Colman R W
Role of kallikrein-kinin system in the pathogenesis of bacterial cell wall-induced inflammation and enterocolitis.
Transactions of the Association of American Physicians 1992;105():229-37.
1991: Pixley R A; Cassello A; De La Cadena R A; Kaufman N; Colman R W
Effect of heparin on the activation of factor XII and the contact system in plasma.
Thrombosis and haemostasis 1991;66(5):540-7.
1991: DeLa Cadena R A; Colman R W
Structure and functions of human kininogens.
Trends in pharmacological sciences 1991;12(7):272-5.
1991: Colman R W
Receptors that activate platelets.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1991;197(3):242-8.
1991: Kaufman N; Page J D; Pixley R A; Schein R; Schmaier A H; Colman R W
Alpha 2-macroglobulin-kallikrein complexes detect contact system activation in hereditary angioedema and human sepsis.
Blood 1991;77(12):2660-7.
1991: Puri R N; Colman R W
Inhibition of ADP-induced platelet shape change and aggregation by o-phthalaldehyde: evidence for covalent modification of cysteine and lysine residues.
Archives of biochemistry and biophysics 1991;286(2):419-27.
1991: Page J D; Colman R W
Localization of distinct functional domains on prekallikrein for interaction with both high molecular weight kininogen and activated factor XII in a 28-kDa fragment (amino acids 141-371).
The Journal of biological chemistry 1991;266(13):8143-8.
1991: Veloso D; Colman R W
Western blot analyses of prekallikrein and its activation products in human plasma.
Thrombosis and haemostasis 1991;65(4):382-8.
1991: DeLa Cadena R A; Laskin K J; Pixley R A; Sartor R B; Schwab J H; Back N; Bedi G S; Fisher R S; Colman R W
Role of kallikrein-kinin system in pathogenesis of bacterial cell wall-induced inflammation.
The American journal of physiology 1991;260(2 Pt 1):G213-9.
1991: Puri R N; Zhou F; Hu C J; Colman R F; Colman R W
High molecular weight kininogen inhibits thrombin-induced platelet aggregation and cleavage of aggregin by inhibiting binding of thrombin to platelets.
Blood 1991;77(3):500-7.
1990: Puri R N; Zhou F X; Colman R F; Colman R W
Plasmin-induced platelet aggregation is accompanied by cleavage of aggregin and indirectly mediated by calpain.
The American journal of physiology 1990;259(6 Pt 1):C862-8.
1990: Bradford H N; Schmaier A H; Colman R W
Kinetics of inhibition of platelet calpain II by human kininogens.
The Biochemical journal 1990;270(1):83-90.
1990: Grant P G; Mannarino A F; Colman R W
Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from the cytosol of human platelets.
Thrombosis research 1990;59(1):105-19.
1990: Colman R W; Rubin R N
Disseminated intravascular coagulation due to malignancy.
Seminars in oncology 1990;17(2):172-86.
1990: Colman R W
Aggregin: a platelet ADP receptor that mediates activation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(5):1425-35.
1990: Schmaier A H; Bradford H N; Lundberg D; Farber A; Colman R W
Membrane expression of platelet calpain.
Blood 1990;75(6):1273-81.
1990: Colman R W
Platelet receptors.
Hematology/oncology clinics of North America 1990;4(1):27-42.
1990: Colman R W
Platelet and neutrophil activation in cardiopulmonary bypass.
The Annals of thoracic surgery 1990;49(1):32-4.
1990: Wang D L; Annamalai A E; Ghosh S; Gewirtz A M; Colman R W
Human platelet factor V is crosslinked to actin by FXIIIa during platelet activation by thrombin.
Thrombosis research 1990;57(1):39-57.
1990: Grant P G; DeCamp D L; Bailey J M; Colman R W; Colman R F
Three new potential cAMP affinity labels. Inactivation of human platelet low Km cAMP phosphodiesterase by 8-[(4-bromo-2,3-dioxobutyl)thio]adenosine 3',5'-cyclic monophosphate.
Biochemistry 1990;29(4):887-94.
1990: Colman R W
ADP receptors in platelets.
Annals of the New York Academy of Sciences 1990;603():198-209; discussion 209-10.
1990: Colman R W
Interactions between the contact system, neutrophils and fibrinogen.
Advances in experimental medicine and biology 1990;281():105-20.
1989: Puri R N; Zhou F X; Colman R F; Colman R W
Cleavage of a 100 kDa membrane protein (aggregin) during thrombin-induced platelet aggregation is mediated by the high affinity thrombin receptors.
Biochemical and biophysical research communications 1989;162(3):1017-24.
1989: Gustafson E J; Schmaier A H; Wachtfogel Y T; Kaufman N; Kucich U; Colman R W
Human neutrophils contain and bind high molecular weight kininogen.
The Journal of clinical investigation 1989;84(1):28-35.
1989: Gustafson E J; Lukasiewicz H; Wachtfogel Y T; Norton K J; Schmaier A H; Niewiarowski S; Colman R W
High molecular weight kininogen inhibits fibrinogen binding to cytoadhesins of neutrophils and platelets.
The Journal of cell biology 1989;109(1):377-87.
1989: Puri R N; Zhou F X; Bradford H; Hu C J; Colman R F; Colman R W
Thrombin-induced platelet aggregation involves an indirect proteolytic cleavage of aggregin by calpain.
Archives of biochemistry and biophysics 1989;271(2):346-58.
1989: Scott C F; Colman R W
Factors influencing the acceleration of human factor XIa inactivation by antithrombin III.
Blood 1989;73(7):1873-9.
1989: Colman R W
Contact systems in infectious disease.
Reviews of infectious diseases 1989;11 Suppl 4():S689-99.
1989: Colman R W; Bradford H N; Warner A H
High molecular weight kininogen, the extracellular inhibitor of thiol proteases, is deficient in hamsters with muscular dystrophy.
Thrombosis research 1989;54(2):115-23.
1989: Wachtfogel Y T; Harpel P C; Edmunds L H; Colman R W
Formation of C1s-C1-inhibitor, kallikrein-C1-inhibitor, and plasmin-alpha 2-plasmin-inhibitor complexes during cardiopulmonary bypass.
Blood 1989;73(2):468-71.
1989: Colman R W; Scott C F; Pixley R A; de la Cadena R A
Effect of heparin on the inhibition of the contact system enzymes.
Annals of the New York Academy of Sciences 1989;556():95-103.
1989: Colman R W
Kallikrein-kinin system in infectious diseases.
Advances in experimental medicine and biology 1989;247A():153-7.
1989: Colman R W; Puri R N; Gustafson E J; Zhou F X; Bradford H
Inhibition of thrombin-induced platelet aggregation by high molecular weight kininogen.
Advances in experimental medicine and biology 1989;247A():349-51.
1989: Gustafson E J; Schmaier A H; Colman R W
High molecular weight kininogen binds to neutrophils.
Advances in experimental medicine and biology 1989;247A():345-8.
1989: Puri R N; Hu C J; Bradford H N; Matsueda R; Umeyama H; Colman R W
Selective inhibition of thrombin- and plasmin-induced platelet aggregation by a synthetic peptide disulfide.
Transactions of the Association of American Physicians 1989;102():13-9.
1989: Pixley R A; Colman R W
A monoclonal antibody recognizing an iscosapeptide sequence in the heavy chain of human factor XII inhibits surface-catalyzed activation.
Advances in experimental medicine and biology 1989;247A():473-6.
1988: Grant P G; Mannarino A F; Colman R W
cAMP-mediated phosphorylation of the low-Km cAMP phosphodiesterase markedly stimulates its catalytic activity.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):9071-5.
1988: Chien P; Pixley R A; Stumpo L G; Colman R W; Schreiber A D
Modulation of the human monocyte binding site for monomeric immunoglobulin G by activated Hageman factor.
The Journal of clinical investigation 1988;82(5):1554-9.
1988: De La Cadena R A; Baglia F A; Johnson C A; Wenk R E; Amernick R; Walsh P N; Colman R W
Naturally occurring human antibodies against two distinct functional domains in the heavy chain of FXI/FXIa.
Blood 1988;72(5):1748-54.
1988: Colman R W; Müller-Esterl W
Subcommittee on contact activation. Nomenclature of kininogens.
Thrombosis and haemostasis 1988;60(2):340-1.
1988: Carvalho A C; DeMarinis S; Scott C F; Silver L D; Schmaier A H; Colman R W
Activation of the contact system of plasma proteolysis in the adult respiratory distress syndrome.
The Journal of laboratory and clinical medicine 1988;112(2):270-7.
1988: Scott C F; Colman R W
A simple and accurate microplate assay for the determination of factor XI in plasma.
The Journal of laboratory and clinical medicine 1988;111(6):708-14.
1988: Huh M M; Schick B P; Schick P K; Colman R W
Covalent crosslinking of human coagulation factor V by activated factor XIII from guinea pig megakaryocytes and human plasma.
Blood 1988;71(6):1693-702.
1988: Wachtfogel Y T; Abrams W; Kucich U; Weinbaum G; Schapira M; Colman R W
Fibronectin degradation products containing the cytoadhesive tetrapeptide stimulate human neutrophil degranulation.
The Journal of clinical investigation 1988;81(5):1310-6.
1988: Colman R W; Figures W R; Wu Q X; Chung S Y; Morinelli T A; Tuszynski G P; Colman R F; Niewiarowski S
Distinction between glycoprotein IIIa and the 100-kDa membrane protein (aggregin) mediating ADP-induced platelet activation.
Archives of biochemistry and biophysics 1988;262(1):298-306.
1988: Colman R W; Flores D N; De La Cadena R A; Scott C F; Cousens L; Barr P J; Hoffman I B; Kueppers F; Fisher D; Idell S
Recombinant alpha 1-antitrypsin Pittsburgh attenuates experimental gram-negative septicemia.
The American journal of pathology 1988;130(2):418-26.
1988: Rao A K; Willis J; Kowalska M A; Wachtfogel Y T; Colman R W
Differential requirements for platelet aggregation and inhibition of adenylate cyclase by epinephrine. Studies of a familial platelet alpha 2-adrenergic receptor defect.
Blood 1988;71(2):494-501.
1988: Bradford H N; Annamalai A; Doshi K; Colman R W
Factor V is activated and cleaved by platelet calpain: comparison with thrombin proteolysis.
Blood 1988;71(2):388-94.
1988: Colman R W; Puri R N; Zhou F X; Colman R F
Aggregin: the platelet receptor mediating activation by ADP.
Progress in clinical and biological research 1988;283():263-77.
1987: Scott C F; Pixley R A; Colman R W
A new assay for high molecular weight kininogen in human plasma using a chromogenic substrate.
Thrombosis research 1987;48(6):685-700.
1987: Veloso D; Silver L D; Hahn S; Colman R W
A monoclonal anti-human plasma prekallikrein antibody that inhibits activation of prekallikrein by factor XIIa on a surface.
Blood 1987;70(4):1053-62.
1987: Figures W R; Scearce L M; DeFeo P; Stewart G; Zhou F; Chen J; Daniel J; Colman R F; Colman R W
Direct evidence for the interaction of the nucleotide affinity analog 5'-p-fluorosulfonylbenzoyl adenosine with a platelet ADP receptor.
Blood 1987;70(3):796-803.
1987: Annamalai A E; Rao A K; Chiu H C; Wang D; Duttá-Roy A K; Walsh P N; Colman R W
Epitope mapping of functional domains of human factor Va with human and murine monoclonal antibodies. Evidence for the interaction of heavy chain with factor Xa and calcium.
Blood 1987;70(1):139-46.
1987: De La Cadena R A; Scott C F; Colman R W
Evaluation of a microassay for human plasma prekallikrein.
The Journal of laboratory and clinical medicine 1987;109(5):601-7.
1987: Gluszko P; Rucinski B; Musial J; Wenger R K; Schmaier A H; Colman R W; Edmunds L H; Niewiarowski S
Fibrinogen receptors in platelet adhesion to surfaces of extracorporeal circuit.
The American journal of physiology 1987;252(3 Pt 2):H615-21.
1987: Schmaier A H; Schutsky D; Farber A; Silver L D; Bradford H N; Colman R W
Determination of the bifunctional properties of high molecular weight kininogen by studies with monoclonal antibodies directed to each of its chains.
The Journal of biological chemistry 1987;262(3):1405-11.
1987: Puri R N; Gustafson E J; Zhou F X; Bradford H; Colman R F; Colman R W
Inhibition of thrombin-induced platelet aggregation by high molecular weight kininogen.
Transactions of the Association of American Physicians 1987;100():232-40.
1987: Colman R W; Scott C F; Schmaier A H; Wachtfogel Y T; Pixley R A; Edmunds L H
Initiation of blood coagulation at artificial surfaces.
Annals of the New York Academy of Sciences 1987;516():253-67.
1986: Colman R W; Figures W R; Scearce L M; Strimpler A M; Zhou F X; Rao A K
Inhibition of collagen-induced platelet activation by 5'-p-fluorosulfonylbenzoyl adenosine: evidence for an adenosine diphosphate requirement and synergistic influence of prostaglandin endoperoxides.
Blood 1986;68(2):565-70.
1986: Gewirtz A M; Keefer M; Doshi K; Annamalai A E; Chiu H C; Colman R W
Biology of human megakaryocyte factor V.
Blood 1986;67(6):1639-48.
1986: Figures W R; Scearce L M; Wachtfogel Y; Chen J; Colman R F; Colman R W
Platelet ADP receptor and alpha 2-adrenoreceptor interaction. Evidence for an ADP requirement for epinephrine-induced platelet activation and an influence of epinephrine on ADP binding.
The Journal of biological chemistry 1986;261(13):5981-6.
1986: Schmaier A H; Bradford H; Silver L D; Farber A; Scott C F; Schutsky D; Colman R W
High molecular weight kininogen is an inhibitor of platelet calpain.
The Journal of clinical investigation 1986;77(5):1565-73.
1986: Annamalai A E; Stewart G J; Hansel B; Memoli M; Chiu H C; Manuel D W; Doshi K; Colman R W
Expression of factor V on human umbilical vein endothelial cells is modulated by cell injury.
Arteriosclerosis (Dallas, Tex.) 1986;6(2):196-202.
1986: Colman R W; Figures W R; Wu Q X; Chung S Y; Morinelli T A; Tuszynski G P; Colman R F; Niewiarowski S
Separation of the 100-kDa membrane protein mediating ADP-induced platelet shape change and activation from glycoprotein IIIa.
Transactions of the Association of American Physicians 1986;99():39-45.
1985: James H L; Wachtfogel Y T; James P L; Zimmerman M; Colman R W; Cohen A B
A unique elastase in human blood platelets.
The Journal of clinical investigation 1985;76(6):2330-7.
1985: Idell S; Kucich U; Fein A; Kueppers F; James H L; Walsh P N; Weinbaum G; Colman R W; Cohen A B
Neutrophil elastase-releasing factors in bronchoalveolar lavage from patients with adult respiratory distress syndrome.
The American review of respiratory disease 1985;132(5):1098-105.
1985: Scott C F; Silver L D; Purdon A D; Colman R W
Cleavage of human high molecular weight kininogen by factor XIa in vitro. Effect on structure and function.
The Journal of biological chemistry 1985;260(19):10856-63.
1985: Mills D C; Figures W R; Scearce L M; Stewart G J; Colman R F; Colman R W
Two mechanisms for inhibition of ADP-induced platelet shape change by 5'-p-fluorosulfonylbenzoyladenosine. Conversion to adenosine, and covalent modification at an ADP binding site distinct from that which inhibits adenylate cyclase.
The Journal of biological chemistry 1985;260(13):8078-83.
1984: Scott C F; Silver L D; Schapira M; Colman R W
Cleavage of human high molecular weight kininogen markedly enhances its coagulant activity. Evidence that this molecule exists as a procofactor.
The Journal of clinical investigation 1984;73(4):954-62.
1984: Colman R W; Silver L D; Purdon A D; Chang J J; Scott C F
Regulation of the coagulant activity and surface binding of high molecular weight kininogen.
Transactions of the Association of American Physicians 1984;97():113-23.
1983: Wachtfogel Y T; Kucich U; James H L; Scott C F; Schapira M; Zimmerman M; Cohen A B; Colman R W
Human plasma kallikrein releases neutrophil elastase during blood coagulation.
The Journal of clinical investigation 1983;72(5):1672-7.
1983: Schapira M; Silver L D; Scott C F; Schmaier A H; Prograis L J; Curd J G; Colman R W
Prekallikrein activation and high-molecular-weight kininogen consumption in hereditary angioedema.
The New England journal of medicine 1983;308(18):1050-3.
1983: Morinelli T A; Niewiarowski S; Kornecki E; Figures W R; Wachtfogel Y; Colman R W
Platelet aggregation and exposure of fibrinogen receptors by prostaglandin endoperoxide analogues.
Blood 1983;61(1):41-9.
1983: Schapira M; James A; Scott C F; Kueppers F; James H L; Cohen A B; Colman R W
Role of high molecular weight kininogen in modulating the inactivation of human plasma kallikrein by plasma protease inhibitors.
Advances in experimental medicine and biology 1983;156():131-41.
1982: Scott C F; Schapira M; James H L; Cohen A B; Colman R W
Inactivation of factor XIa by plasma protease inhibitors: predominant role of alpha 1-protease inhibitor and protective effect of high molecular weight kininogen.
The Journal of clinical investigation 1982;69(4):844-52.
1982: Schapira M; Silver L D; Scott C F; Colman R W
New and rapid functional assay for C1 inhibitor in human plasma.
Blood 1982;59(4):719-24.
1982: Schapira M; Scott C F; James A; Silver L D; Kueppers F; James H L; Colman R W
High molecular weight kininogen or its light chain protects human plasma kallikrein from inactivation by plasma protease inhibitors.
Biochemistry 1982;21(3):567-72.
1981: Figures W R; Niewiarowski S; Morinelli T A; Colman R F; Colman R W
Affinity labeling of a human platelet membrane protein with 5'-p-fluorosulfonylbenzoyl adenosine. Concomitant inhibition of ADP-induced platelet aggregation and fibrinogen receptor exposure.
The Journal of biological chemistry 1981;256(15):7789-95.
1980: Colman R W; Figures W R; Colman R F; Morinelli T A; Niewiarowski S; Mills D C
Identification of two distinct adenosine diphosphate receptors in human platelets.
Transactions of the Association of American Physicians 1980;93():305-16.

Sign-in to see more