FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Yong-Guang Yang

Research Profile

Living Beings

Procedures

Anatomy

Disorders

Graft vs Host Disease

Chemicals & Drugs

Physiology

Co-author Network

Publications

TOP 3
M Murata; Tetsuya Uchida; Yong-Guang Yang; Alexander Lezhava; Haruyasu Kinashi
A large inversion in the linear chromosome of Streptomyces griseus caused by replicative transposition of a new Tn3 family transposon.
Yong-Guang Yang
CD47 in xenograft rejection and tolerance induction.
Takashi Onoe; Hannes Kalscheuer; Meredith Chittenden; Guiling Zhao; Yong-Guang Yang; Megan Sykes
Homeostatic expansion and phenotypic conversion of human T cells depend on peripheral interactions with APCs.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Yong-Guang Yang (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: M Murata; Tetsuya Uchida; Yong-Guang Yang; Alexander Lezhava; Haruyasu Kinashi
A large inversion in the linear chromosome of Streptomyces griseus caused by replicative transposition of a new Tn3 family transposon.
Archives of microbiology 2011;193(4):299-306.
2010: Yong-Guang Yang
CD47 in xenograft rejection and tolerance induction.
Xenotransplantation 2010;17(4):267-73.
2010: Takashi Onoe; Hannes Kalscheuer; Meredith Chittenden; Guiling Zhao; Yong-Guang Yang; Megan Sykes
Homeostatic expansion and phenotypic conversion of human T cells depend on peripheral interactions with APCs.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):6756-65.
2010: Hui Wang; Xiaojian Wu; Yuantao Wang; Per-Arne Oldenborg; Yong-Guang Yang
CD47 is required for suppression of allograft rejection by donor-specific transfusion.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(7):3401-7.
2010: Sang-Soo Kim; Dan Peer; Priti Kumar; Sandesh Subramanya; Huaquan Wu; Deshratn Asthana; Katsuyoshi Habiro; Yong-Guang Yang; N Manjunath; Motomu Shimaoka; Premlata Shankar
RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(2):370-6.
2009: Changhong Xing; Sunryung Lee; Woo Jean Kim; Hui Wang; Yong-Guang Yang; MingMing Ning; Xiaoying Wang; Eng H Lo
Neurovascular effects of CD47 signaling: promotion of cell death, inflammation, and suppression of angiogenesis in brain endothelial cells in vitro.
Journal of neuroscience research 2009;87(11):2571-7.
2009: Diana M Brainard; Edward Seung; Nicole Frahm; Annaiah Cariappa; Charles C Bailey; William K Hart; Hae-Sook Shin; Sarah F Brooks; Heather L Knight; Quentin Eichbaum; Yong-Guang Yang; Megan Sykes; Bruce D Walker; Gordon J Freeman; Shiv Pillai; Susan V Westmoreland; Christian Brander; Andrew D Luster; Andrew M Tager
Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice.
Journal of virology 2009;83(14):7305-21.
2009: Katsuyoshi Habiro; Megan Sykes; Yong-Guang Yang
Induction of human T-cell tolerance to pig xenoantigens via thymus transplantation in mice with an established human immune system.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(6):1324-9.
2009: Guang Jin; Kiyoshi Tsuji; Changhong Xing; Yong-Guang Yang; Xiaoying Wang; Eng H Lo
CD47 gene knockout protects against transient focal cerebral ischemia in mice.
Experimental neurology 2009;217(1):165-70.
2009: Hui Wang; Wannee Asavaroengchai; Beow Yong Yeap; Min-Guang Wang; Shumei Wang; Megan Sykes; Yong-Guang Yang
Paradoxical effects of IFN-gamma in graft-versus-host disease reflect promotion of lymphohematopoietic graft-versus-host reactions and inhibition of epithelial tissue injury.
Blood 2009;113(15):3612-9.
2009: Changhong Xing; Sunryung Lee; Woo Jean Kim; Guang Jin; Yong-Guang Yang; Xunming Ji; Xiaoying Wang; Eng H Lo
Role of oxidative stress and caspase 3 in CD47-mediated neuronal cell death.
Journal of neurochemistry 2009;108(2):430-6.
2008: Ichiro Shimizu; Yasuhiro Fudaba; Akira Shimizu; Yong-Guang Yang; Megan Sykes
Comparison of human T cell repertoire generated in xenogeneic porcine and human thymus grafts.
Transplantation 2008;86(4):601-10.
2008: Priti Kumar; Hong-Seok Ban; Sang-Soo Kim; Haoquan Wu; Todd Pearson; Dale L Greiner; Amale Laouar; Jiahong Yao; Viraga Haridas; Katsuyoshi Habiro; Yong-Guang Yang; Ji-Hoon Jeong; Kuen Yong Lee; Yong-Hee Kim; Sung Wan Kim; Matthias Peipp; Georg H Fey; N Manjunath; Leonard D Shultz; Sang-Kyung Lee; Premlata Shankar
T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice.
Cell 2008;134(4):577-86.
2008: Noriko Tonomura; Katsuyoshi Habiro; Akira Shimizu; Megan Sykes; Yong-Guang Yang
Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model.
Blood 2008;111(8):4293-6.
2008: Noriko Tonomura; Akira Shimizu; Shumei Wang; Kazuhiko Yamada; Vaja Tchipashvili; Gordon C Weir; Yong-Guang Yang
Pig islet xenograft rejection in a mouse model with an established human immune system.
Xenotransplantation 2008;15(2):129-35.
2007: Patricia S Cho; Diana P Lo; Krzysztof J Wikiel; Haley Rowland; Rebecca C Coburn; Isabel M McMorrow; Jennifer G Goodrich; J Scott Arn; Robert A Billiter; Stuart L Houser; Akira Shimizu; Yong-Guang Yang; David H Sachs; Christene A Huang
Establishment of transplantable porcine tumor cell lines derived from MHC-inbred miniature swine.
Blood 2007;110(12):3996-4004.
2007: Hui Wang; Maria Lucia Madariaga; Shumei Wang; Nico van Rooijen; Per-Arne Oldenborg; Yong-Guang Yang
Lack of CD47 on nonhematopoietic cells induces split macrophage tolerance to CD47null cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13744-9.
2007: Yong-Guang Yang; Megan Sykes
Xenotransplantation: current status and a perspective on the future.
Nature reviews. Immunology 2007;7(7):519-31.
2007: Kentaro Ide; Hui Wang; Hiroyuki Tahara; Jianxiang Liu; Xiaoying Wang; Toshimasa Asahara; Megan Sykes; Yong-Guang Yang; Hideki Ohdan
Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):5062-6.
2007: Hui Wang; Jon VerHalen; Maria Lucia Madariaga; Shuanglin Xiang; Shumei Wang; Ping Lan; Per-Arne Oldenborg; Megan Sykes; Yong-Guang Yang
Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.
Blood 2007;109(2):836-42.
2007: Wannee Asavaroengchai; Hui Wang; Shumei Wang; Lan Wang; Roderick Bronson; Megan Sykes; Yong-Guang Yang
An essential role for IFN-gamma in regulation of alloreactive CD8 T cells following allogeneic hematopoietic cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(1):46-55.
2006: Ping Lan; Noriko Tonomura; Akira Shimizu; Shumei Wang; Yong-Guang Yang
Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation.
Blood 2006;108(2):487-92.
2006: Yuanxin Xu; Yong-Guang Yang; Hideki Ohdan; Ryan David; David Harper; Cecelia Wu; Huw S Kruger-Grey; Aron D Thall; Michel Awwad; Megan Sykes
Characterization of anti-Gal antibody-producing cells of baboons and humans.
Transplantation 2006;81(6):940-8.
2005: Yong-Guang Yang; Hui Wang; Wannee Asavaroengchai; Bimalangshu R Dey
Role of Interferon-gamma in GVHD and GVL.
Cellular & molecular immunology 2005;2(5):323-9.
2005: Maria A Giovino; Hui Wang; Megan Sykes; Yong-Guang Yang
Role of VLA-4 and VLA-5 in ex vivo maintenance of human and pig hematopoiesis in human stroma-supported long-term cultures.
Experimental hematology 2005;33(3):363-70.
2004: Hiroshi Eguchi; Christoph Knosalla; Ping Lan; Jane Cheng; Bintou Diouf; Lan Wang; Masahiro Abe; Henk-Jan Schuurman; David H Sachs; Megan Sykes; David K C Cooper; Yong-Guang Yang
T cells from presensitized donors fail to cause graft-versus-host disease in a pig-to-mouse xenotransplantation model.
Transplantation 2004;78(11):1609-17.
2004: Yong-Guang Yang
Application of xenogeneic stem cells for induction of transplantation tolerance: present state and future directions.
Springer seminars in immunopathology 2004;26(1-2):187-200.
2004: Yong-Guang Yang; James C Wood; Ping Lan; Robert A Wilkinson; Megan Sykes; Jay A Fishman; Clive Patience
Mouse retrovirus mediates porcine endogenous retrovirus transmission into human cells in long-term human-porcine chimeric mice.
The Journal of clinical investigation 2004;114(5):695-700.
2004: Ping Lan; Lan Wang; Bintou Diouf; Hiroshi Eguchi; Hui Su; Roderick Bronson; David H Sachs; Megan Sykes; Yong-Guang Yang
Induction of human T-cell tolerance to porcine xenoantigens through mixed hematopoietic chimerism.
Blood 2004;103(10):3964-9.
2004: Andreas Lechner; Yong-Guang Yang; Robyn A Blacken; Lan Wang; anna nolan; Joel F Habener
No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo.
Diabetes 2004;53(3):616-23.
2003: Toshiyasu Kawahara; Hideki Ohdan; Guiling Zhao; Yong-Guang Yang; Megan Sykes
Peritoneal cavity B cells are precursors of splenic IgM natural antibody-producing cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5406-14.
2003: Annie C Le Guern; Maria A Giovino; Masahiro Abe; Pierre R Theodore; Jin Qi; Julian D Down; David H Sachs; Megan Sykes; Yong-Guang Yang
Stem cell activity of porcine c-kit+ hematopoietic cells.
Experimental hematology 2003;31(9):833-40.
2002: Yong-Guang Yang; Jin Qi; Min-Guang Wang; Megan Sykes
Donor-derived interferon gamma separates graft-versus-leukemia effects and graft-versus-host disease induced by donor CD8 T cells.
Blood 2002;99(11):4207-15.
2002: Masahiro Abe; Jin Qi; Megan Sykes; Yong-Guang Yang
Mixed chimerism induces donor-specific T-cell tolerance across a highly disparate xenogeneic barrier.
Blood 2002;99(10):3823-9.
2002: Masahiro Abe; Jane Cheng; Jin Qi; Roseann M Glaser; Aron D Thall; Megan Sykes; Yong-Guang Yang
Elimination of porcine hemopoietic cells by macrophages in mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):621-8.
2002: Frederic Preffer; David Dombkowski; Megan Sykes; David T Scadden; Yong-Guang Yang
Lineage-negative side-population (SP) cells with restricted hematopoietic capacity circulate in normal human adult blood: immunophenotypic and functional characterization.
Stem cells (Dayton, Ohio) 2002;20(5):417-27.
2001: Hideki Ohdan; Kirsten G Swenson; Hiroshi Kitamura; Yong-Guang Yang; Megan Sykes
Tolerization of Gal alpha 1,3Gal-reactive B cells in pre-sensitized alpha 1,3-galactosyltransferase-deficient mice by nonmyeloablative induction of mixed chimerism.
Xenotransplantation 2001;8(4):227-38.
2001: Hideki Ohdan; Yong-Guang Yang; Kirsten G Swenson; H Kitamura; Megan Sykes
T cell and B cell tolerance to GALalpha1,3GAL-expressing heart xenografts is achieved in alpha1,3-galactosyltransferase-deficient mice by nonmyeloablative induction of mixed chimerism.
Transplantation 2001;71(11):1532-42.
2000: Hideki Ohdan; Kirsten G Swenson; Huw S Kruger Gray; Yong-Guang Yang; Y Xu; Aron D Thall; Megan Sykes
Mac-1-negative B-1b phenotype of natural antibody-producing cells, including those responding to Gal alpha 1,3Gal epitopes in alpha 1,3-galactosyltransferase-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5518-29.
2000: M Abe; A M Chen; J Qi; David H Sachs; Megan Sykes; Yong-Guang Yang
Porcine stem cell factor facilitates long-lasting porcine hematopoietic engraftment in murine recipients.
Transplantation proceedings 2000;32(5):1047.
2000: AM Chen; Y Zhou; Kirsten G Swenson; David H Sachs; Megan Sykes; Yong-Guang Yang
Porcine stem cell engraftment and seeding of murine thymus with class II+ cells in mice expressing porcine cytokines: toward tolerance induction across discordant xenogeneic barriers.
Transplantation 2000;69(12):2484-90.
2000: Hideki Ohdan; Yong-Guang Yang; Kirsten G Swenson; Aron D Thall; Megan Sykes
In vivo T-cell depletion enhances production of anti-GALalpha1,3GAL natural antibodies in alpha1,3-galactosyltransferase-deficient mice.
Transplantation 2000;69(5):910-3.
2000: Tao Cheng; Neil Rodrigues; H Shen; Yong-Guang Yang; David Dombkowski; Megan Sykes; David T Scadden
Hematopoietic stem cell quiescence maintained by p21cip1/waf1.
Science (New York, N.Y.) 2000;287(5459):1804-8.
2000: Yong-Guang Yang
The role of interleukin-12 and interferon-gamma in GVHD and GVL.
Cytokines, cellular & molecular therapy 2000;6(1):41-6.
2000: Yong-Guang Yang; AM Chen; L J Garrett; JJ Sergio; Pierre R Theodore; Michel Awwad; J VerHalen; D M Bodine; David H Sachs; Megan Sykes
Development and analysis of transgenic mice expressing porcine hematopoietic cytokines: a model for achieving durable porcine hematopoietic chimerism across an extensive xenogeneic barrier.
Xenotransplantation 2000;7(1):58-64.
2000: Yong-Guang Yang; AM Chen; JJ Sergio; Y Zhou; Megan Sykes
Role of antibody-independent complement activation in rejection of porcine bone marrow cells in mice.
Transplantation 2000;69(1):163-5.
1999: Hideki Ohdan; Yong-Guang Yang; Akira Shimizu; Kirsten G Swenson; Megan Sykes
Mixed chimerism induced without lethal conditioning prevents T cell- and anti-Gal alpha 1,3Gal-mediated graft rejection.
The Journal of clinical investigation 1999;104(3):281-90.
1999: Bimalangshu R Dey; Yong-Guang Yang; Frederic Preffer; Akira Shimizu; Kirsten G Swenson; David Dombkowski; Megan Sykes
The fate of donor T-cell receptor transgenic T cells with known host antigen specificity in a graft-versus-host disease model.
Transplantation 1999;68(1):141-9.
1999: Yong-Guang Yang; Megan Sykes
The role of interleukin-12 in preserving the graft-versus-leukemia effect of allogeneic CD8 T cells independently of GVHD.
Leukemia & lymphoma 1999;33(5-6):409-20.
1999: Hideki Ohdan; Yong-Guang Yang; Megan Sykes
Reduction of anti-Gal alpha 1-3Gal natural antibodies in sera of alpha 1,3-galactosyltransferase-deficient mice receiving Gal-positive bone marrow transplantation.
Transplantation proceedings 1999;31(1-2):945-6.
1999: Michele Pelot; Denise A Pearson; Kirsten G Swenson; Guiling Zhao; Jeffrey Sachs; Yong-Guang Yang; Megan Sykes
Lymphohematopoietic graft-vs.-host reactions can be induced without graft-vs.-host disease in murine mixed chimeras established with a cyclophosphamide-based nonmyeloablative conditioning regimen.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1999;5(3):133-43.
1998: Yong-Guang Yang; Bimalangshu R Dey; JJ Sergio; Denise A Pearson; Megan Sykes
Donor-derived interferon gamma is required for inhibition of acute graft-versus-host disease by interleukin 12.
The Journal of clinical investigation 1998;102(12):2126-35.
1998: Megan Sykes; Hideki Ohdan; Jennifer O Manilay; T Wekerle; Yong-Guang Yang
Hematopoietic chimerism and tolerance of T cells, B cells, and NK cells.
Transplantation proceedings 1998;30(8):4020.
1998: Yong-Guang Yang; E deGoma; Rolf N Barth; JJ Sergio; Megan Sykes
B-cell reconstitution and xenoreactive anti-pig natural antibody production in severe combined immunodeficient mice reconstituted with immunocompetent B cells from varying sources.
Transplantation 1998;66(1):89-95.
1998: Bimalangshu R Dey; Yong-Guang Yang; GL Szot; Denise A Pearson; Megan Sykes
Interleukin-12 inhibits graft-versus-host disease through an Fas-mediated mechanism associated with alterations in donor T-cell activation and expansion.
Blood 1998;91(9):3315-22.
1998: Yong-Guang Yang; E deGoma; Hideki Ohdan; Jennifer Bracy; Y Xu; John Iacomini; Aron D Thall; Megan Sykes
Tolerization of anti-Galalpha1-3Gal natural antibody-forming B cells by induction of mixed chimerism.
The Journal of experimental medicine 1998;187(8):1335-42.
1997: Yong-Guang Yang; JJ Sergio; Denise A Pearson; GL Szot; Akira Shimizu; Megan Sykes
Interleukin-12 preserves the graft-versus-leukemia effect of allogeneic CD8 T cells while inhibiting CD4-dependent graft-versus-host disease in mice.
Blood 1997;90(11):4651-60.
1997: Yong-Guang Yang; Bimalangshu R Dey; JJ Sergio; Megan Sykes
Interleukin-12 prevents severe acute graft-versus-host disease (GVHD) and GVHD-associated immune dysfunction in a fully major histocompatibility complex haplotype-mismatched murine bone marrow transplantation model.
Transplantation 1997;64(9):1343-52.
1997: Megan Sykes; Y Zhao; Yong-Guang Yang
Tolerance induction for xenotransplantation.
World journal of surgery 1997;21(9):932-8.
1996: Yong-Guang Yang; R M Glaser; R Monroy; Kirsten G Swenson; Megan Sykes
Enhanced porcine hematopoiesis in mice receiving donor-specific interleukin-3.
Transplantation proceedings 1996;28(2):655.