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Michael Schumm

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Vanya Icheva; Simone Kayser; Christina Kyzirakos; Peter Lang; Michaela Nathrath; Michael Schumm; Wolfgang Schwinger; Stefan Stevanovic; Sebastian Tuve; Daniel Wolff; Michael H Albert; Wolfgang A Bethge; Johann Greil; Rupert Handgretinger; Tobias Feuchtinger
Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1-specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantation.
Matthias Pfeiffer; Michael Schumm; Rupert Handgretinger; Ingo Müller; P Lang
IL-15-stimulated CD3/CD19-depleted stem-cell boosts in relapsed pediatric patients after haploidentical SCT.
Birgit Federmann; Rupert Handgretinger; Lothar Kanz; Lambros Kordelas; Christoph Meisner; Michael Schumm; Rainer Schwerdtfeger; Matthias Stelljes; Gernot Stuhler; Wichard Vogel; Dietrich W Beelen; Gerhard Behre; Martin Bornhauser; Maximilian Christopeit; Christoph Faul; Wolfgang A Bethge
Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: a phase II study.

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All Publications

2013: Vanya Icheva; Simone Kayser; Christina Kyzirakos; Peter Lang; Michaela Nathrath; Michael Schumm; Wolfgang Schwinger; Stefan Stevanovic; Sebastian Tuve; Daniel Wolff; Michael H Albert; Wolfgang A Bethge; Johann Greil; Rupert Handgretinger; Tobias Feuchtinger
Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1-specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013;31(1):39-48.
2012: Matthias Pfeiffer; Michael Schumm; Rupert Handgretinger; Ingo Müller; P Lang
IL-15-stimulated CD3/CD19-depleted stem-cell boosts in relapsed pediatric patients after haploidentical SCT.
Leukemia 2012;26(11):2435-9.
2012: Birgit Federmann; Rupert Handgretinger; Lothar Kanz; Lambros Kordelas; Christoph Meisner; Michael Schumm; Rainer Schwerdtfeger; Matthias Stelljes; Gernot Stuhler; Wichard Vogel; Dietrich W Beelen; Gerhard Behre; Martin Bornhauser; Maximilian Christopeit; Christoph Faul; Wolfgang A Bethge
Haploidentical allogeneic hematopoietic cell transplantation in adults using CD3/CD19 depletion and reduced intensity conditioning: a phase II study.
Haematologica 2012;97(10):1523-31.
2012: Lena Oevermann; Patrick Schlegel; Michael Schumm; Heiko-Manuel Teltschik; Tobias Feuchtinger; Peter Lang; Rupert Handgretinger
Immune reconstitution and strategies for rebuilding the immune system after haploidentical stem cell transplantation.
Annals of the New York Academy of Sciences 2012;1266():161-70.
2011: Patrick Schlegel; Paul-Gerhard Schlegel; Michael Schumm; Heiko-Manuel Teltschik; Peter Bader; Tobias Feuchtinger; Johann Greil; Rupert Handgretinger; Thomas Klingebiel; Ewa Koscielniak; Matthias Pfeiffer; Peter Lang
Long-term IL-2 therapy after transplantation of T cell depleted stem cells from alternative donors in children.
Best practice & research. Clinical haematology 2011;24(3):443-52.
2011: B Federmann; M Hägele; Matthias Pfeiffer; Stefan Wirths; Michael Schumm; Christoph Faul; Wichard Vogel; Rupert Handgretinger; Lothar Kanz; Wolfgang A Bethge
Immune reconstitution after haploidentical hematopoietic cell transplantation: impact of reduced intensity conditioning and CD3/CD19 depleted grafts.
Leukemia 2011;25(1):121-9.
2010: Tobias Feuchtinger; Kathrin Opherk; Wolfgang A Bethge; Max S Topp; Friedhelm R Schuster; Eva M Weissinger; Mohamad Mohty; Reuven Or; Michael Maschan; Michael Schumm; Klaus Hamprecht; Rupert Handgretinger; Peter Lang; Hermann Einsele
Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation.
Blood 2010;116(20):4360-7.
2010: Tobias Feuchtinger; Kathrin Opherk; Oliver Bicanic; Michael Schumm; Götz Ulrich Grigoleit; Klaus Hamprecht; Gerhard Jahn; Rupert Handgretinger; Peter Lang
Dendritic cell vaccination in an allogeneic stem cell recipient receiving a transplant from a human cytomegalovirus (HCMV)-seronegative donor: induction of a HCMV-specific T(helper) cell response.
Cytotherapy 2010;12(7):945-50.
2010: Matthias Pfeiffer; Tobias Feuchtinger; Heiko-Manuel Teltschik; Michael Schumm; Ingo Müller; Rupert Handgretinger; Peter Lang
Reconstitution of natural killer cell receptors influences natural killer activity and relapse rate after haploidentical transplantation of T- and B-cell depleted grafts in children.
Haematologica 2010;95(8):1381-8.
2010: Harald F Langer; Jürgen W von der Ruhr; Karin Daub; Tanja Schoenberger; Konstantinos Stellos; Andreas E May; Hannah Schnell; Alexandra Gauss; Ramona Hafner; Peter Lang; Michael Schumm; Hans-Jörg Bühring; Karin Klingel; Sabine Conrad; Martin Schaller; Marc van Zandvoort; Gundram Jung; Stefanie Dimmeler; Thomas Skutella; Meinrad Gawaz
Capture of endothelial progenitor cells by a bispecific protein/monoclonal antibody molecule induces reendothelialization of vascular lesions.
Journal of molecular medicine (Berlin, Germany) 2010;88(7):687-99.
2009: Meral Esen; Song Le; Regina Schleucher; Michael Gässler; Egeruan Babatunde Imoukhuede; Nathalie Imbault; Odile Leroy; Søren Jepsen; Birgitte Walther Knudsen; Michael Schumm; Jürgen Knobloch; Michael Theisen; Benjamin Mordmüller
Safety and immunogenicity of GMZ2 - a MSP3-GLURP fusion protein malaria vaccine candidate.
Vaccine 2009;27(49):6862-8.
2009: Tobias Feuchtinger; Matthias Pfeiffer; A Pfaffle; H-M Teltschik; D Wernet; Michael Schumm; Ramin Lotfi; Rupert Handgretinger; Peter Lang
Cytolytic activity of NK cell clones against acute childhood precursor-B-cell leukaemia is influenced by HLA class I expression on blasts and the differential KIR phenotype of NK clones.
Bone marrow transplantation 2009;43(11):875-81.
2008: Martina Ulrich; Alina Petre; Nikolay Youhnovski; Franziska Prömm; Markus Schirle; Michael Schumm; Ralph S Pero; Alfred Doyle; James Checkel; Hirohito Kita; Nethaji Thiyagarajan; K Ravi Acharya; Peter Schmid-Grendelmeier; Hans-Uwe Simon; Heinz Schwarz; Masato Tsutsui; Hiroaki Shimokawa; Gabriel Bellon; James J Lee; Michael Przybylski; Gerd Döring
Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase.
The Journal of biological chemistry 2008;283(42):28629-40.
2008: Tobias Feuchtinger; Celine Richard; Stefanie Joachim; Michael H Scheible; Michael Schumm; Klaus Hamprecht; David Martin; Gerhard Jahn; Rupert Handgretinger; Peter Lang
Clinical grade generation of hexon-specific T cells for adoptive T-cell transfer as a treatment of adenovirus infection after allogeneic stem cell transplantation.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(2):199-206.
2008: Selim Kuçi; Zyrafete Kuçi; Susanne Schmid; Guido Seitz; I Müller; Andreas Dufke; T Leimig; G Murti; Roland Jurecic; Michael Schumm; Peter Lang; Gernot Bruchelt; Peter Bader; Thomas Klingebiel; Dietrich Niethammer; Rupert Handgretinger
Efficient in vitro generation of adult multipotent cells from mobilized peripheral blood CD133+ cells.
Cell proliferation 2008;41(1):12-27.
2008: Konstantinos Stellos; Harald Langer; Karin Daub; Tanja Schoenberger; Alexandra Gauss; Tobias Geisler; Boris Bigalke; Iris Mueller; Michael Schumm; Iris Schaefer; Peter Seizer; Bjoern F Kraemer; Dorothea Siegel-Axel; Andreas E May; Stephan Lindemann; Meinrad Gawaz
Platelet-derived stromal cell-derived factor-1 regulates adhesion and promotes differentiation of human CD34+ cells to endothelial progenitor cells.
Circulation 2008;117(2):206-15.
2008: Rupert Handgretinger; X Chen; Matthias Pfeiffer; Michael Schumm; I Mueller; Tobias Feuchtinger; G Hale; Peter Lang
Cellular immune reconstitution after haploidentical transplantation in children.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(1 Suppl 1):59-65.
2008: Peter Lang; Ingo Mueller; Johann Greil; Peter Bader; Michael Schumm; Matthias Pfeiffer; Walter Hoelle; Thomas Klingebiel; Frank Heinzelmann; Claus Belka; Paul G Schlegel; Bernhard Kremens; Willi Woessmann; Rupert Handgretinger
Retransplantation with stem cells from mismatched related donors after graft rejection in pediatric patients.
Blood cells, molecules & diseases 2008;40(1):33-9.
2007: Matthias Pfeiffer; Michael Schumm; Tobias Feuchtinger; Klaus Dietz; Rupert Handgretinger; Peter Lang
Intensity of HLA class I expression and KIR-mismatch determine NK-cell mediated lysis of leukaemic blasts from children with acute lymphatic leukaemia.
British journal of haematology 2007;138(1):97-100.
2007: Michael Schumm; Tobias Feuchtinger; Matthias Pfeiffer; W Hoelle; Wolfgang A Bethge; Martin Ebinger; Selim Kuci; Rupert Handgretinger; Peter Lang
Flow cytometry with anti HLA-antibodies: a simple but highly sensitive method for monitoring chimerism and minimal residual disease after HLA-mismatched stem cell transplantation.
Bone marrow transplantation 2007;39(12):767-73.
2006: Wolfgang A Bethge; Matthias Haegele; Christoph Faul; Peter Lang; Michael Schumm; Martin Bornhauser; Rupert Handgretinger; Lothar Kanz
Haploidentical allogeneic hematopoietic cell transplantation in adults with reduced-intensity conditioning and CD3/CD19 depletion: fast engraftment and low toxicity.
Experimental hematology 2006;34(12):1746-52.
2006: Peter Lang; Matthias Pfeiffer; I Müller; Michael Schumm; Martin Ebinger; Ewa Koscielniak; Tobias Feuchtinger; J Föll; D Martin; Rupert Handgretinger
Haploidentical stem cell transplantation in patients with pediatric solid tumors: preliminary results of a pilot study and analysis of graft versus tumor effects.
Klinische Pädiatrie 2006;218(6):321-6.
2006: Tobias Feuchtinger; Susanne Matthes-Martin; Celine Richard; Thomas Lion; Monika Fuhrer; Klaus Hamprecht; Rupert Handgretinger; Christina Peters; Friedhelm R Schuster; Robert Beck; Michael Schumm; Ramin Lotfi; Gerhard Jahn; Peter Lang
Safe adoptive transfer of virus-specific T-cell immunity for the treatment of systemic adenovirus infection after allogeneic stem cell transplantation.
British journal of haematology 2006;134(1):64-76.
2006: Zyrafete Kuçi; Guido Seitz; Selim Kuçi; Hermann Kreyenberg; Michael Schumm; Peter Lang; Dietrich Niethammer; Rupert Handgretinger; Gernot Bruchelt
Pitfalls in detection of contaminating neuroblastoma cells by tyrosine hydroxylase RT-PCR due to catecholamine-producing hematopoietic cells.
Anticancer research 2006;26(3A):2075-80.
2006: Harald Langer; Andreas E May; Karin Daub; Ulrich Heinzmann; Peter Lang; Michael Schumm; Dietmar Vestweber; Steffen Massberg; Tanja Schönberger; Iris Pfisterer; Antonis K Hatzopoulos; Meinrad Gawaz
Adherent platelets recruit and induce differentiation of murine embryonic endothelial progenitor cells to mature endothelial cells in vitro.
Circulation research 2006;98(2):e2-10.
2006: Michael Schumm; Rupert Handgretinger; Matthias Pfeiffer; Tobias Feuchtinger; Selim Kuci; Christoph Faul; Wichard Vogel; Wolfgang A Bethge; Peter Lang
Determination of residual T- and B-cell content after immunomagnetic depletion: proposal for flow cytometric analysis and results from 103 separations.
Cytotherapy 2006;8(5):465-72.
2005: Peter Lang; Michael Schumm; Johann Greil; Peter Bader; Thomas Klingebiel; I Müller; Tobias Feuchtinger; Matthias Pfeiffer; Paul G Schlegel; Dietrich Niethammer; Rupert Handgretinger
A comparison between three graft manipulation methods for haploidentical stem cell transplantation in pediatric patients: preliminary results of a pilot study.
Klinische Pädiatrie 2005;217(6):334-8.
2005: Thomas Klingebiel; Peter Lang; Michael Schumm; Ulrike Koehl; Peter Bader; Dirk Schwabe; Paul G Schlegel; Matthias Eyrich; Johann Greil; James F Beck; Dietrich Niethammer; Rupert Handgretinger
Experiences with haploidentical stem cell transplantation in children with acute lymphoblastic leukemia.
Pathologie-biologie 2005;53(3):159-61.
2005: Tobias Feuchtinger; Julia Lücke; Klaus Hamprecht; Celine Richard; Rupert Handgretinger; Michael Schumm; Johann Greil; Thomas Bock; Dietrich Niethammer; Peter Lang
Detection of adenovirus-specific T cells in children with adenovirus infection after allogeneic stem cell transplantation.
British journal of haematology 2005;128(4):503-9.
2004: Peter Lang; Johann Greil; Peter Bader; Rupert Handgretinger; Thomas Klingebiel; Michael Schumm; Paul G Schlegel; Tobias Feuchtinger; Matthias Pfeiffer; Hans Scheel-Walter; Monika Führer; David Martin; Dietrich Niethammer
Long-term outcome after haploidentical stem cell transplantation in children.
Blood cells, molecules & diseases 2004;33(3):281-7.
2004: Peter Lang; A Griesinger; Klaus Hamprecht; Tobias Feuchtinger; Michael Schumm; F Neuhäuser; Johann Greil; D Martin; Rupert Handgretinger; Dietrich Niethammer
Antiviral activity against CMV-infected fibroblasts in pediatric patients transplanted with CD34(+)-selected allografts from alternative donors.
Human immunology 2004;65(5):423-31.
2004: P Lang; T Klingebiel; Michael Schumm; R Handgretinger; Johann Greil; James F Beck; D Niethammer; P Bader
Correction of persistent thrombocytopenia by a boost of CD133+ selected stem cells in a patient transplanted for Wiskott-Aldrich syndrome 10 years ago.
Bone marrow transplantation 2004;33(8):879-80.
2004: Tobias Feuchtinger; Peter Lang; Klaus Hamprecht; Michael Schumm; Johann Greil; Gerhard Jahn; Dietrich Niethammer; Hermann Einsele
Isolation and expansion of human adenovirus-specific CD4+ and CD8+ T cells according to IFN-gamma secretion for adjuvant immunotherapy.
Experimental hematology 2004;32(3):282-9.
2004: Matthias Eyrich; Christine Leiler; Tanja Croner; Peter Lang; Michael Schumm; Beate Mascher; Karin Schilbach; Thomas Klingebiel; Rupert Handgretinger; Dietrich Niethammer; Paul G Schlegel
Impaired T-cell activation and cytokine productivity after transplantation of positively selected CD34+ allogeneic hematopoietic stem cells.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5(4):329-40.
2004: Peter Lang; Thomas Klingebiel; Peter Bader; Johann Greil; Michael Schumm; Paul G Schlegel; Matthias Eyrich; S Mueller-Weihrich; Dietrich Niethammer; Rupert Handgretinger
Transplantation of highly purified peripheral-blood CD34+ progenitor cells from related and unrelated donors in children with nonmalignant diseases.
Bone marrow transplantation 2004;33(1):25-32.
2004: Peter Lang; Peter Bader; Michael Schumm; Tobias Feuchtinger; Hermann Einsele; Monika Führer; Christof Weinstock; Rupert Handgretinger; Selim Kuci; David Martin; Dietrich Niethammer; Johann Greil
Transplantation of a combination of CD133+ and CD34+ selected progenitor cells from alternative donors.
British journal of haematology 2004;124(1):72-9.
2004: P Lang; R Handgretinger; Johann Greil; P Bader; Michael Schumm; T Klingebiel; D Niethammer
Transplantation of CD34+ enriched allografts in children with nonmalignant diseases: does graft manipulation necessarily result in high incidence of graft failure?
Bone marrow transplantation 2004;33(1):125-6; author reply 127.
2003: M Koch; Peter Lang; Peter Bader; Hermann Kreyenberg; Michael Schumm; Hans Scheel-Walter; A Hochhaus; Dietrich Niethammer; Johann Greil
Successful unrelated allogeneic stem cell transplantation after treatment of lymphoid blast crisis CML with imatinib and imatinib-containing conditioning regimen in a 16-year-old male.
Bone marrow transplantation 2003;32(5):541-2.
2003: Matthias Eyrich; Christine Leiler; Peter Lang; Karin Schilbach; Michael Schumm; Peter Bader; Johann Greil; Thomas Klingebiel; Rupert Handgretinger; Dietrich Niethammer; Paul G Schlegel
A prospective comparison of immune reconstitution in pediatric recipients of positively selected CD34+ peripheral blood stem cells from unrelated donors vs recipients of unmanipulated bone marrow from related donors.
Bone marrow transplantation 2003;32(4):379-90.
2003: Peter Lang; Rupert Handgretinger; Dietrich Niethammer; Paul G Schlegel; Michael Schumm; Johann Greil; Peter Bader; Corinna Engel; Hans Scheel-Walter; Matthias Eyrich; Thomas Klingebiel
Transplantation of highly purified CD34+ progenitor cells from unrelated donors in pediatric leukemia.
Blood 2003;101(4):1630-6.
2003: Selim Kuçi; Johannes T Wessels; Hans-Jörg Bühring; Karin Schilbach; Michael Schumm; Guido Seitz; Jürgen Löffler; Peter Bader; Paul G Schlegel; Dietrich Niethammer; Rupert Handgretinger
Identification of a novel class of human adherent CD34- stem cells that give rise to SCID-repopulating cells.
Blood 2003;101(3):869-76.
2002: Rupert Handgretinger; Peter Lang; K Ihm; Michael Schumm; A Geiselhart; Ewa Koscielniak; Barbara Hero; Thomas Klingebiel; Dietrich Niethammer
Isolation and transplantation of highly purified autologous peripheral CD34(+) progenitor cells: purging efficacy, hematopoietic reconstitution and long-term outcome in children with high-risk neuroblastoma.
Bone marrow transplantation 2002;29(9):731-6.
2002: Peter Lang; Matthias Pfeiffer; Rupert Handgretinger; Michael Schumm; B Demirdelen; S Stanojevic; Thomas Klingebiel; U Köhl; Selim Kuci; Dietrich Niethammer
Clinical scale isolation of T cell-depleted CD56+ donor lymphocytes in children.
Bone marrow transplantation 2002;29(6):497-502.
2001: Rupert Handgretinger; Peter Lang; Michael Schumm; Matthias Pfeiffer; S Gottschling; B Demirdelen; Peter Bader; Selim Kuci; Thomas Klingebiel; Dietrich Niethammer
Immunological aspects of haploidentical stem cell transplantation in children.
Annals of the New York Academy of Sciences 2001;938():340-57; discussion 357-8.
2001: Rupert Handgretinger; Thomas Klingebiel; Peter Lang; Michael Schumm; S Neu; A Geiselhart; Peter Bader; Paul G Schlegel; Johann Greil; D Stachel; R J Herzog; Dietrich Niethammer
Megadose transplantation of purified peripheral blood CD34(+) progenitor cells from HLA-mismatched parental donors in children.
Bone marrow transplantation 2001;27(8):777-83.
1999: Peter Lang; Michael Schumm; G Taylor; Thomas Klingebiel; S Neu; A Geiselhart; Selim Kuci; Dietrich Niethammer; Rupert Handgretinger
Clinical scale isolation of highly purified peripheral CD34+progenitors for autologous and allogeneic transplantation in children.
Bone marrow transplantation 1999;24(6):583-9.
1999: Rupert Handgretinger; Michael Schumm; Peter Lang; Johann Greil; A Reiter; Peter Bader; Dietrich Niethammer; Thomas Klingebiel
Transplantation of megadoses of purified haploidentical stem cells.
Annals of the New York Academy of Sciences 1999;872():351-61; discussion 361-2.
1999: Michael Schumm; Peter Lang; G Taylor; Selim Kuçi; Thomas Klingebiel; Hans-Jörg Bühring; A Geiselhart; Dietrich Niethammer; Rupert Handgretinger
Isolation of highly purified autologous and allogeneic peripheral CD34+ cells using the CliniMACS device.
Journal of hematotherapy 1999;8(2):209-18.
1998: Rupert Handgretinger; Peter Lang; Michael Schumm; G Taylor; S Neu; E Koscielnak; Dietrich Niethammer; Thomas Klingebiel
Isolation and transplantation of autologous peripheral CD34+ progenitor cells highly purified by magnetic-activated cell sorting.
Bone marrow transplantation 1998;21(10):987-93.
1998: Selim Kuçi; G Taylor; S Neu; Michael Schumm; Dietrich Niethammer; Rupert Handgretinger
Phenotypic and functional characterization of mobilized peripheral blood CD34+ cells coexpressing different levels of c-Kit.
Leukemia research 1998;22(4):355-63.