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Nicola Simola

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Lucia Frau; A Plumitallo; Nicola Simola; Micaela Morelli
Microglial and astroglial activation by 3,4-methylenedioxymethamphetamine (MDMA) in mice depends on S(+) enantiomer and is associated with an increase in body temperature and motility.
Micaela Morelli; Lucia Frau; Nicola Simola
Alteration in the progression of dopamine neuron degeneration: may caffeine offer new perspective?
Nicola Simola; Giulia Costa; Sandro Fenu; Annalisa Pinna; A Plumitallo; Micaela Morelli
Pharmacological characterization of 50-kHz ultrasonic vocalizations in rats: comparison of the effects of different psychoactive drugs and relevance in drug-induced reward.

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All Publications

2013: Lucia Frau; A Plumitallo; Nicola Simola; Micaela Morelli
Microglial and astroglial activation by 3,4-methylenedioxymethamphetamine (MDMA) in mice depends on S(+) enantiomer and is associated with an increase in body temperature and motility.
Journal of neurochemistry 2013;124(1):69-78.
2012: Micaela Morelli; Lucia Frau; Nicola Simola
Alteration in the progression of dopamine neuron degeneration: may caffeine offer new perspective?
Experimental neurology 2012;237(1):218-22.
2012: Nicola Simola; Giulia Costa; Sandro Fenu; Annalisa Pinna; A Plumitallo; Micaela Morelli
Pharmacological characterization of 50-kHz ultrasonic vocalizations in rats: comparison of the effects of different psychoactive drugs and relevance in drug-induced reward.
Neuropharmacology 2012;63(2):224-34.
2012: Micaela Morelli; Nicola Simola; Fabio Blandini; Robert A Hauser
A(2A) Receptor Antagonism and Dyskinesia in Parkinson's Disease.
Parkinson's disease 2012;2012():489853.
2011: Micaela Morelli; Nicola Simola
Methylxanthines and drug dependence: a focus on interactions with substances of abuse.
Handbook of experimental pharmacology 2011;(200):483-507.
2010: Nicola Simola; Annalisa Pinna; Sandro Fenu
Pharmacological therapy of Parkinson's disease: current options and new avenues.
Recent patents on CNS drug discovery 2010;5(3):221-38.
2010: Micaela Morelli; Nicola Simola
Can dietary substances protect against Parkinson's disease? The case of caffeine.
Experimental neurology 2010;225(2):246-9.
2010: Nicola Simola; Sean T Ma; Timothy Schallert
Influence of acute caffeine on 50-kHz ultrasonic vocalizations in male adult rats and relevance to caffeine-mediated psychopharmacological effects.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2010;13(1):123-32.
2009: Nicola Simola; GAETANO DI CHIARA; W M U Daniels; T Schallert; Micaela Morelli
Priming of rotational behavior by a dopamine receptor agonist in Hemiparkinsonian rats: movement-dependent induction.
Neuroscience 2009;158(4):1625-31.
2008: Nicola Simola; Sandro Fenu; Pier G Baraldi; Mojgan Aghazadeh Tabrizi; Micaela Morelli
Blockade of globus pallidus adenosine A(2A) receptors displays antiparkinsonian activity in 6-hydroxydopamine-lesioned rats treated with D(1) or D(2) dopamine receptor agonists.
Synapse (New York, N.Y.) 2008;62(5):345-51.
2008: Nicola Simola; Micaela Morelli; Philip Seeman
Increase of dopamine D2(High) receptors in the striatum of rats sensitized to caffeine motor effects.
Synapse (New York, N.Y.) 2008;62(5):394-7.
2008: Nicola Simola; Diego Bustamante; Annalisa Pinna; Silvia Pontis; Paola Morales; Micaela Morelli; Mario Herrera-Marschitz
Acute perinatal asphyxia impairs non-spatial memory and alters motor coordination in adult male rats.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2008;185(4):595-601.
2008: Nicola Simola; Micaela Morelli; Annalisa Pinna
Adenosine A2A receptor antagonists and Parkinson's disease: state of the art and future directions.
Current pharmaceutical design 2008;14(15):1475-89.
2007: Elisabetta Tronci; Nicola Simola; Franco Borsini; Nicoletta Schintu; Lucia Frau; Paolo Carminati; Micaela Morelli
Characterization of the antiparkinsonian effects of the new adenosine A2A receptor antagonist ST1535: acute and subchronic studies in rats.
European journal of pharmacology 2007;566(1-3):94-102.
2007: Nicola Simola; Micaela Morelli; Anna R Carta
The 6-hydroxydopamine model of Parkinson's disease.
Neurotoxicity research 2007;11(3-4):151-67.
2006: Nicola Simola; Elisabetta Tronci; Annalisa Pinna; Micaela Morelli
Subchronic-intermittent caffeine amplifies the motor effects of amphetamine in rats.
Amino acids 2006;31(4):359-63.
2006: Nicola Simola; Sandro Fenu; Pier G Baraldi; Mojgan Aghazadeh Tabrizi; Micaela Morelli
Involvement of globus pallidus in the antiparkinsonian effects of adenosine A(2A) receptor antagonists.
Experimental neurology 2006;202(1):255-7.
2006: Nicola Simola; Sandro Fenu; Pier G Baraldi; Mojgan Aghazadeh Tabrizi; Micaela Morelli
Dopamine and adenosine receptor interaction as basis for the treatment of Parkinson's disease.
Journal of the neurological sciences 2006;248(1-2):48-52.
2006: Nicola Simola; Omar Cauli; Micaela Morelli
Sensitization to caffeine and cross-sensitization to amphetamine: influence of individual response to caffeine.
Behavioural brain research 2006;172(1):72-9.
2006: Elisabetta Tronci; Nicola Simola; Anna R Carta; M Antonietta De Luca; Micaela Morelli
Potentiation of amphetamine-mediated responses in caffeine-sensitized rats involves modifications in A2A receptors and zif-268 mRNAs in striatal neurons.
Journal of neurochemistry 2006;98(4):1078-89.
2005: Annalisa Pinna; Jadwiga Wardas; Nicola Simola; Micaela Morelli
New therapies for the treatment of Parkinson's disease: adenosine A2A receptor antagonists.
Life sciences 2005;77(26):3259-67.
2004: Nicola Simola; Sandro Fenu; Pier G Baraldi; Mojgan Aghazadeh Tabrizi; Micaela Morelli
Blockade of adenosine A2A receptors antagonizes parkinsonian tremor in the rat tacrine model by an action on specific striatal regions.
Experimental neurology 2004;189(1):182-8.