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Rongtuan Lin

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Penghua Wang; Zhengyun Xu; Guang Yang; Long Yang; Fuping You; Gong Cheng; Erol Fikrig; Rongtuan Lin; Qiang Sun; Richard E Sutton
UBXN1 Interferes with Rig-I-like Receptor-Mediated Antiviral Immune Response by Targeting MAVS.
Marie-Line Goulet; Elias K Haddad; Meztli Arguello; Siddharth Balachandran; S Mehdi Belgnaoui; Mark Cameron; Khader Ghneim; Valérie Janelle; Ulrich Kalinke; Erin I Lafferty; Alain Lamarre; Rongtuan Lin; David Olagnier; Marilene Paquet; Suzanne Paz; Suraj Peri; Salman Qureshi; Stephanie Richards; Rafick-Pierre Sekaly; Andrew Smith; Peter Wilkinson; Zhengyun Xu; John Hiscott
Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity.
Mingsheng Cai; Meili Li; Rongtuan Lin; Qiong Lu; Karen L Mossman; Kezhen Wang; Shuai Wang; Jinghua Yan; Chunfu Zheng
The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway.

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2013: Penghua Wang; Zhengyun Xu; Guang Yang; Long Yang; Fuping You; Gong Cheng; Erol Fikrig; Rongtuan Lin; Qiang Sun; Richard E Sutton
UBXN1 Interferes with Rig-I-like Receptor-Mediated Antiviral Immune Response by Targeting MAVS.
Cell reports 2013;3(4):1057-70.
2013: Marie-Line Goulet; Elias K Haddad; Meztli Arguello; Siddharth Balachandran; S Mehdi Belgnaoui; Mark Cameron; Khader Ghneim; Valérie Janelle; Ulrich Kalinke; Erin I Lafferty; Alain Lamarre; Rongtuan Lin; David Olagnier; Marilene Paquet; Suzanne Paz; Suraj Peri; Salman Qureshi; Stephanie Richards; Rafick-Pierre Sekaly; Andrew Smith; Peter Wilkinson; Zhengyun Xu; John Hiscott
Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity.
PLoS pathogens 2013;9(4):e1003298.
2013: Mingsheng Cai; Meili Li; Rongtuan Lin; Qiong Lu; Karen L Mossman; Kezhen Wang; Shuai Wang; Jinghua Yan; Chunfu Zheng
The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-κB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway.
PloS one 2013;8(1):e54586.
2012: S Mehdi Belgnaoui; Ivan Dikic; Marie-Line Goulet; John Hiscott; Kazuhiro Iwai; Marjolein Kikkert; Suzanne Paz; Sara Samuel; Qiang Sun; Rongtuan Lin
Linear ubiquitination of NEMO negatively regulates the interferon antiviral response through disruption of the MAVS-TRAF3 complex.
Cell host & microbe 2012;12(2):211-22.
2012: Junji Xing; Rongtuan Lin; Karen L Mossman; Shuai Wang; Chunfu Zheng
Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5.
Journal of virology 2012;86(7):3528-40.
2012: Bing Liu; Cuiyan Ren; Guoyan Geng; Rongtuan Lin; Jian Hui Wu
Learning from estrogen receptor antagonism: structure-based identification of novel antiandrogens effective against multiple clinically relevant androgen receptor mutants.
Chemical biology & drug design 2012;79(3):300-12.
2012: Pierre Génin; John Hiscott; Rongtuan Lin; Ahmet Civas
Recruitment of histone deacetylase 3 to the interferon-A gene promoters attenuates interferon expression.
PloS one 2012;7(6):e38336.
2011: Huifang Zhu; Shuping Li; Rongtuan Lin; Shuai Wang; Junji Xing; Chunfu Zheng; Karen L Mossman
Varicella-zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3.
Journal of virology 2011;85(21):11079-89.
2011: Sujan Piya; Dai-Wu Seol; Peter I Song; John Hiscott; Rongtuan Lin; Ae Ran Moon; Tae-Hyoung Kim
Suppression of IRF4 by IRF1, 3, and 7 in Noxa expression is a necessary event for IFN-γ-mediated tumor elimination.
Molecular cancer research : MCR 2011;9(10):1356-65.
2011: Suzanne Paz; Myriam Vilasco; Steven J Werden; Meztli Arguello; Deshanthe Joseph-Pillai; Tiejun Zhao; Thi Lien-Anh Nguyen; Qiang Sun; Eliane F Meurs; Rongtuan Lin; John Hiscott
A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response.
Cell research 2011;21(6):895-910.
2011: Humera Ahmad; Rachel Gubbels; Erica Ehlers; Florencia Meyer; Thomas Waterbury; Rongtuan Lin; Luwen Zhang
Kaposi sarcoma-associated herpesvirus degrades cellular Toll-interleukin-1 receptor domain-containing adaptor-inducing beta-interferon (TRIF).
The Journal of biological chemistry 2011;286(10):7865-72.
2011: Louise Larocque; Alex Bliu; Ranran Xu; Abebaw Diress; Junzhi Wang; Rongtuan Lin; Runtao He; Michel Girard; Xuguang Li
Bioactivity determination of native and variant forms of therapeutic interferons.
Journal of biomedicine & biotechnology 2011;2011():174615.
2011: Monika Oldak; Liv Tolzmann; Artur Wnorowski; Marta Justyna Podgórska; Steffi Silling; Rongtuan Lin; John Hiscott; Cornelia Sigrid Lissi Müller; Thomas Vogt; Hans Smola; Sigrun Smola
Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7.
Journal of virology 2011;85(1):178-88.
2010: Rongtuan Lin; Suzanne Paz; John Hiscott
Tom70 imports antiviral immunity to the mitochondria.
Cell research 2010;20(9):971-3.
2010: Peyman Nakhaei; John Hiscott; Rongtuan Lin
STING-ing the antiviral pathway.
Journal of molecular cell biology 2010;2(3):110-2.
2009: Shun Li; Donglei Zhang; Long Yang; Julia V Burnier; Ni Wang; Rongtuan Lin; Eunice R Lee; Robert I Glazer; Pnina Brodt
The IGF-I receptor can alter the matrix metalloproteinase repertoire of tumor cells through transcriptional regulation of PKC-{alpha}.
Molecular endocrinology (Baltimore, Md.) 2009;23(12):2013-25.
2009: Peyman Nakhaei; Thibault Mesplede; Mayra Solis; Qiang Sun; Tiejun Zhao; Long Yang; Tsung-Hsien Chuang; Carl F Ware; Rongtuan Lin; John Hiscott
The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation.
PLoS pathogens 2009;5(11):e1000650.
2009: Damien Vitour; Stéphanie Dabo; Malek Ahmadi Pour; Myriam Vilasco; Pierre-Olivier Vidalain; Yves Jacob; Mariana Mezel-Lemoine; Suzanne Paz; Meztli Arguello; Rongtuan Lin; Frédéric Tangy; John Hiscott; Eliane F Meurs
Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS.
The Journal of biological chemistry 2009;284(33):21797-809.
2009: Suzanne Paz; Myriam Vilasco; Meztli Arguello; Qiang Sun; Judith Lacoste; Thi Lien-Anh Nguyen; Tiejun Zhao; Elena A Shestakova; Scott Zaari; Annie Bibeau-Poirier; Marc J Servant; Rongtuan Lin; Eliane F Meurs; John Hiscott
Ubiquitin-regulated recruitment of IkappaB kinase epsilon to the MAVS interferon signaling adapter.
Molecular and cellular biology 2009;29(12):3401-12.
2009: Pierre Génin; Rongtuan Lin; John Hiscott; Ahmet Civas
Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7.
Molecular and cellular biology 2009;29(12):3435-50.
2009: Delphine Goubau; Raphaëlle Romieu-Mourez; Mayra Solis; Eduardo Hernandez; Thibault Mesplède; Rongtuan Lin; Douglas Leaman; John Hiscott
Transcriptional re-programming of primary macrophages reveals distinct apoptotic and anti-tumoral functions of IRF-3 and IRF-7.
European journal of immunology 2009;39(2):527-40.
2009: Long Yang; Tiejun Zhao; Xiaoliu Shi; Peyman Nakhaei; Yunling Wang; Qiang Sun; John Hiscott; Rongtuan Lin
Functional analysis of a dominant negative mutation of interferon regulatory factor 5.
PloS one 2009;4(5):e5500.
2008: David Escors; Luciene Lopes; Rongtuan Lin; John Hiscott; Shizuo Akira; Roger J Davis; Mary K Collins
Targeting dendritic cell signaling to regulate the response to immunization.
Blood 2008;111(6):3050-61.
2007: Santhana G Devaraj; Nan Wang; Zihong Chen; Zhongbin Chen; Monica Tseng; Naina Barretto; Rongtuan Lin; Clarence Peters; Chien-Te K Tseng; Susan C Baker; Kui Li
Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus.
The Journal of biological chemistry 2007;282(44):32208-21.
2007: Ehssan Sharif-Askari; Peyman Nakhaei; Stephanie Oliere; Vanessa Tumilasci; Eduardo Hernandez; Peter Wilkinson; Rongtuan Lin; John Bell; John Hiscott
Bax-dependent mitochondrial membrane permeabilization enhances IRF3-mediated innate immune response during VSV infection.
Virology 2007;365(1):20-33.
2007: Tiejun Zhao; Long Yang; Qiang Sun; Meztli Arguello; Dean W Ballard; John Hiscott; Rongtuan Lin
The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways.
Nature immunology 2007;8(6):592-600.
2007: Taija E Pietilä; Ville Veckman; Anne Lehtonen; Rongtuan Lin; John Hiscott; Ilkka Julkunen
Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(1):253-61.
2006: John Hiscott; Judith Lacoste; Rongtuan Lin
Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: disruption by hepatitis C virus NS3-4A protease.
Biochemical pharmacology 2006;72(11):1477-84.
2006: Raphaëlle Romieu-Mourez; Mayra Solis; Alessandra Nardin; Delphine Goubau; Véronique Baron-Bodo; Rongtuan Lin; Bernard Massie; Margarita Salcedo; John Hiscott
Distinct roles for IFN regulatory factor (IRF)-3 and IRF-7 in the activation of antitumor properties of human macrophages.
Cancer research 2006;66(21):10576-85.
2006: Jennifer Harris; Stéphanie Olière; Sonia Sharma; Qiang Sun; Rongtuan Lin; John Hiscott; Nathalie Grandvaux
Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKK epsilon.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2527-35.
2006: Jukka Sirén; Tadaatsu Imaizumi; Devanand Sarkar; Taija E Pietilä; Diana L Noah; Rongtuan Lin; John Hiscott; Robert M Krug; Paul B Fisher; Ilkka Julkunen; Sampsa Matikainen
Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines.
Microbes and infection / Institut Pasteur 2006;8(8):2013-20.
2006: Rongtuan Lin; Judith Lacoste; Peyman Nakhaei; Qiang Sun; Long Yang; Suzanne Paz; Peter Wilkinson; Ilkka Julkunen; Damien Vitour; Eliane F Meurs; John Hiscott
Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage.
Journal of virology 2006;80(12):6072-83.
2006: Meztli Arguello; Suzanne Paz; Eduardo Hernandez; Catherine Corriveau-Bourque; Lama M Fawaz; John Hiscott; Rongtuan Lin
Leukotriene A4 hydrolase expression in PEL cells is regulated at the transcriptional level and leads to increased leukotriene B4 production.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):7051-61.
2006: Sampsa Matikainen; Jukka Sirén; Jorma Tissari; Ville Veckman; Jaana Pirhonen; Martina Severa; Qiang Sun; Rongtuan Lin; Seppo Meri; Gilles Uzé; John Hiscott; Ilkka Julkunen
Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression.
Journal of virology 2006;80(7):3515-22.
2006: Ahmet Civas; Pierre Génin; Pierre Morin; Rongtuan Lin; John Hiscott
Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon.
The Journal of biological chemistry 2006;281(8):4856-66.
2006: John Hiscott; Rongtuan Lin; Peyman Nakhaei; Suzanne Paz
MasterCARD: a priceless link to innate immunity.
Trends in molecular medicine 2006;12(2):53-6.
2006: Stanislas Goriely; Céline Molle; Muriel Nguyen; Valentina Albarani; Najate Ouled Haddou; Rongtuan Lin; Dominique De Wit; Véronique Flamand; Fabienne Willems; Michel Goldman
Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation.
Blood 2006;107(3):1078-84.
2006: Rongtuan Lin; Long Yang; Peyman Nakhaei; Qiang Sun; Ehssan Sharif-Askari; Ilkka Julkunen; John Hiscott
Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.
The Journal of biological chemistry 2006;281(4):2095-103.
2006: John Hiscott; Rongtuan Lin
Inhibition of the interferon antiviral response by hepatitis C virus.
Expert review of clinical immunology 2006;2(1):49-58.
2006: Pasi Kaukinen; Maarit Sillanpää; Sergei V Kotenko; Rongtuan Lin; John Hiscott; Krister Melén; Ilkka Julkunen
Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression.
Virology journal 2006;3():66.
2006: Suzanne Paz; Qiang Sun; Peyman Nakhaei; Raphaëlle Romieu-Mourez; Delphine Goubau; Ilkka Julkunen; Rongtuan Lin; John Hiscott
Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.
Cellular and molecular biology (Noisy-le-Grand, France) 2006;52(1):17-28.
2005: John Hiscott; Rongtuan Lin
IRF-3 releases its inhibitions.
Structure (London, England : 1993) 2005;13(9):1235-6.
2005: Yan Desfosses; Mayra Solis; Qiang Sun; Nathalie Grandvaux; Carine Van Lint; Arsène Burny; Anne Gatignol; Mark A Wainberg; Rongtuan Lin; John Hiscott
Regulation of human immunodeficiency virus type 1 gene expression by clade-specific Tat proteins.
Journal of virology 2005;79(14):9180-91.
2005: Nathalie Grandvaux; François Gaboriau; Jennifer Harris; Benjamin R Tenoever; Rongtuan Lin; John Hiscott
Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response.
The FEBS journal 2005;272(12):3120-31.
2005: Adrien Breiman; Nathalie Grandvaux; Rongtuan Lin; Catherine Ottone; Shizuo Akira; Mitsutoshi Yoneyama; Takashi Fujita; John Hiscott; Eliane F Meurs
Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon.
Journal of virology 2005;79(7):3969-78.
2005: Rongtuan Lin; Long Yang; Meztli Arguello; Claudia Penafuerte; John Hiscott
A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization.
The Journal of biological chemistry 2005;280(4):3088-95.
2005: Marie-Chloé Boulanger; Chen Liang; Rodney S Russell; Rongtuan Lin; Mark T Bedford; Mark A Wainberg; Stéphane Richard
Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression.
Journal of virology 2005;79(1):124-31.
2004: Benjamin R Tenoever; Sonia Sharma; Wen Zou; Qiang Sun; Nathalie Grandvaux; Ilkka Julkunen; Hiroaki Hemmi; M Yamamoto; Shizuo Akira; Wen-Chen Yeh; Rongtuan Lin; John Hiscott
Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity.
Journal of virology 2004;78(19):10636-49.
2004: Marco Sgarbanti; Meztli Arguello; Benjamin R Tenoever; Angela Battistini; Rongtuan Lin; John Hiscott
A requirement for NF-kappaB induction in the production of replication-competent HHV-8 virions.
Oncogene 2004;23(34):5770-80.
2004: Rongtuan Lin; Ryan S Noyce; Susan E Collins; Roger D Everett; Karen Mossman
The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes.
Journal of virology 2004;78(4):1675-84.
2003: John Hiscott; Nathalie Grandvaux; Sonia Sharma; Benjamin R Tenoever; Marc J Servant; Rongtuan Lin
Convergence of the NF-kappaB and interferon signaling pathways in the regulation of antiviral defense and apoptosis.
Annals of the New York Academy of Sciences 2003;1010():237-48.
2003: Sonia Sharma; Benjamin R Tenoever; Nathalie Grandvaux; Guo-Ping Zhou; Rongtuan Lin; John Hiscott
Triggering the interferon antiviral response through an IKK-related pathway.
Science (New York, N.Y.) 2003;300(5622):1148-51.
2003: Jonathan Bramson; Kelley Dayball; Jennifer R Hall; James B Millar; Mark Miller; Yonghong Wan; Rongtuan Lin; John Hiscott
Super-activated interferon-regulatory factors can enhance plasmid immunization.
Vaccine 2003;21(13-14):1363-70.
2003: Marc J Servant; Nathalie Grandvaux; Benjamin R Tenoever; Delphine Duguay; Rongtuan Lin; John Hiscott
Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA.
The Journal of biological chemistry 2003;278(11):9441-7.
2003: Meztli Arguello; Marco Sgarbanti; Eduardo Hernandez; Yaël Mamane; Sonia Sharma; Marc J Servant; Rongtuan Lin; John Hiscott
Disruption of the B-cell specific transcriptional program in HHV-8 associated primary effusion lymphoma cell lines.
Oncogene 2003;22(7):964-73.
2002: Yaël Mamane; Nathalie Grandvaux; Eduardo Hernandez; Sonia Sharma; Steve A Innocente; Jonathan M Lee; Nazli Azimi; Rongtuan Lin; John Hiscott
Repression of IRF-4 target genes in human T cell leukemia virus-1 infection.
Oncogene 2002;21(44):6751-65.
2002: Delphine Duguay; François Mercier; John Stagg; Daniel Martineau; Jonathan Bramson; Marc J Servant; Rongtuan Lin; Jacques Galipeau; John Hiscott
In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors.
Cancer research 2002;62(18):5148-52.
2002: Nathalie Grandvaux; Marc J Servant; Benjamin R Tenoever; Ganes C Sen; Siddharth Balachandran; Glen N Barber; Rongtuan Lin; John Hiscott
Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes.
Journal of virology 2002;76(11):5532-9.
2002: Benjamin R Tenoever; Marc J Servant; Nathalie Grandvaux; Rongtuan Lin; John Hiscott
Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation.
Journal of virology 2002;76(8):3659-69.
2002: Pierre Morin; Jose Bragança; Marie-Thérèse Bandu; Rongtuan Lin; John Hiscott; Janine Doly; Ahmet Civas
Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription.
Journal of molecular biology 2002;316(5):1009-22.
2002: Marc J Servant; Benjamin R Tenoever; Rongtuan Lin
Overlapping and distinct mechanisms regulating IRF-3 and IRF-7 function.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2002;22(1):49-58.
2001: Antonella Casola; Roberto P Garofalo; Helene A Haeberle; T F Elliott; Rongtuan Lin; Mohammad Jamaluddin; allan brasier
Multiple cis regulatory elements control RANTES promoter activity in alveolar epithelial cells infected with respiratory syncytial virus.
Journal of virology 2001;75(14):6428-39.
2001: Rongtuan Lin; Pierre Genin; Yaël Mamane; Marco Sgarbanti; Angela Battistini; William J Harrington; Glen N Barber; John Hiscott
HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators.
Oncogene 2001;20(7):800-11.
2001: Marc J Servant; B ten Oever; Cecile Le Page; L Conti; S Gessani; Ilkka Julkunen; Rongtuan Lin; John Hiscott
Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3.
The Journal of biological chemistry 2001;276(1):355-63.
2000: Rongtuan Lin; Yaël Mamane; John Hiscott
Multiple regulatory domains control IRF-7 activity in response to virus infection.
The Journal of biological chemistry 2000;275(44):34320-7.
2000: Sonia Sharma; Yaël Mamane; Nathalie Grandvaux; J Bartlett; L Petropoulos; Rongtuan Lin; John Hiscott
Activation and regulation of interferon regulatory factor 4 in HTLV type 1-infected T lymphocytes.
AIDS research and human retroviruses 2000;16(16):1613-22.
2000: Rongtuan Lin; P Génin; Yaël Mamane; John Hiscott
Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7.
Molecular and cellular biology 2000;20(17):6342-53.
2000: P Génin; M Algarté; P Roof; Rongtuan Lin; John Hiscott
Regulation of RANTES chemokine gene expression requires cooperativity between NF-kappa B and IFN-regulatory factor transcription factors.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(10):5352-61.
2000: C Heylbroeck; Siddharth Balachandran; Marc J Servant; C DeLuca; Glen N Barber; Rongtuan Lin; John Hiscott
The IRF-3 transcription factor mediates Sendai virus-induced apoptosis.
Journal of virology 2000;74(8):3781-92.
2000: Yaël Mamane; Sonia Sharma; L Petropoulos; Rongtuan Lin; John Hiscott
Posttranslational regulation of IRF-4 activity by the immunophilin FKBP52.
Immunity 2000;12(2):129-40.
1999: H Nguyen; L Teskey; Rongtuan Lin; John Hiscott
Identification of the secretory leukocyte protease inhibitor (SLPI) as a target of IRF-1 regulation.
Oncogene 1999;18(39):5455-63.
1999: Yaël Mamane; C Heylbroeck; P Génin; M Algarté; Marc J Servant; Cecile Le Page; C DeLuca; H Kwon; Rongtuan Lin; John Hiscott
Interferon regulatory factors: the next generation.
Gene 1999;237(1):1-14.
1999: C DeLuca; H Kwon; Rongtuan Lin; Mark A Wainberg; John Hiscott
NF-kappaB activation and HIV-1 induced apoptosis.
Cytokine & growth factor reviews 1999;10(3-4):235-53.
1999: Rongtuan Lin; Yaël Mamane; John Hiscott
Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains.
Molecular and cellular biology 1999;19(4):2465-74.
1999: M Algarté; H Nguyen; C Heylbroeck; Rongtuan Lin; John Hiscott
IkappaB-mediated inhibition of virus-induced beta interferon transcription.
Journal of virology 1999;73(4):2694-702.
1999: Rongtuan Lin; C Heylbroeck; Pierre Genin; PAULA PITHA-ROWE; John Hiscott
Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription.
Molecular and cellular biology 1999;19(2):959-66.
1999: W Spencer; H Kwon; P Crépieux; N Leclerc; Rongtuan Lin; John Hiscott
Taxol selectively blocks microtubule dependent NF-kappaB activation by phorbol ester via inhibition of IkappaBalpha phosphorylation and degradation.
Oncogene 1999;18(2):495-505.
1999: Rongtuan Lin; John Hiscott
A role for casein kinase II phosphorylation in the regulation of IRF-1 transcriptional activity.
Molecular and cellular biochemistry 1999;191(1-2):169-80.
1999: John Hiscott; PAULA PITHA-ROWE; Pierre Genin; H Nguyen; C Heylbroeck; Yaël Mamane; M Algarte; Rongtuan Lin
Triggering the interferon response: the role of IRF-3 transcription factor.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(1):1-13.
1998: Rongtuan Lin; C Heylbroeck; PAULA PITHA-ROWE; John Hiscott
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation.
Molecular and cellular biology 1998;18(5):2986-96.
1998: H Kwon; Nadine Pelletier; C DeLuca; Pierre Genin; S Cisternas; Rongtuan Lin; Mark A Wainberg; John Hiscott
Inducible expression of IkappaBalpha repressor mutants interferes with NF-kappaB activity and HIV-1 replication in Jurkat T cells.
The Journal of biological chemistry 1998;273(13):7431-40.
1997: P Crépieux; H Kwon; N Leclerc; W Spencer; Stéphane Richard; Rongtuan Lin; John Hiscott
I kappaB alpha physically interacts with a cytoskeleton-associated protein through its signal response domain.
Molecular and cellular biology 1997;17(12):7375-85.
1997: H Nguyen; Rongtuan Lin; John Hiscott
Activation of multiple growth regulatory genes following inducible expression of IRF-1 or IRF/RelA fusion proteins.
Oncogene 1997;15(12):1425-35.
1997: John Hiscott; P Beauparlant; P Crepieux; C DeLuca; H Kwon; Rongtuan Lin; L Petropoulos
Cellular and viral protein interactions regulating I kappa B alpha activity during human retrovirus infection.
Journal of leukocyte biology 1997;62(1):82-92.
1997: J P Aumais; Han S Lee; Rongtuan Lin; John H White
Selective interaction of hsp90 with an estrogen receptor ligand-binding domain containing a point mutation.
The Journal of biological chemistry 1997;272(18):12229-35.
1996: L Petropoulos; Rongtuan Lin; John Hiscott
Human T cell leukemia virus type 1 tax protein increases NF-kappa B dimer formation and antagonizes the inhibitory activity of the I kappa B alpha regulatory protein.
Virology 1996;225(1):52-64.
1996: P Beauparlant; H Kwon; M Clarke; Rongtuan Lin; Nahum Sonenberg; Mark A Wainberg; John Hiscott
Transdominant mutants of I kappa B alpha block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication.
Journal of virology 1996;70(9):5777-85.
1996: P Beauparlant; Rongtuan Lin; John Hiscott
The role of the C-terminal domain of I kappa B alpha in protein degradation and stabilization.
The Journal of biological chemistry 1996;271(18):10690-6.
1996: Rongtuan Lin; P Beauparlant; C Makris; Sylvain Meloche; John Hiscott
Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability.
Molecular and cellular biology 1996;16(4):1401-9.
1995: A Roulston; Rongtuan Lin; P Beauparlant; Mark A Wainberg; John Hiscott
Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors.
Microbiological reviews 1995;59(3):481-505.
1995: H Nguyen; A Mustafa; John Hiscott; Rongtuan Lin
Transcription factor IRF-2 exerts its oncogenic phenotype through the DNA binding/transcription repression domain.
Oncogene 1995;11(3):537-44.
1995: R Bitar; P Beauparlant; Rongtuan Lin; PAULA PITHA-ROWE; John Hiscott
Retrovirus-mediated transfer of nuclear factor-kappa B subunit genes modulates I kappa B alpha and interferon beta expression.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(8):965-76.
1995: Rongtuan Lin; D Gewert; John Hiscott
Differential transcriptional activation in vitro by NF-kappa B/Rel proteins.
The Journal of biological chemistry 1995;270(7):3123-31.
1994: N Pepin; A Roulston; J Lacoste; Rongtuan Lin; John Hiscott
Subcellular redistribution of HTLV-1 Tax protein by NF-kappa B/Rel transcription factors.
Virology 1994;204(2):706-16.
1994: E Garoufalis; I Kwan; Rongtuan Lin; A Mustafa; N Pepin; A Roulston; J Lacoste; John Hiscott
Viral induction of the human beta interferon promoter: modulation of transcription by NF-kappa B/rel proteins and interferon regulatory factors.
Journal of virology 1994;68(8):4707-15.