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Ellen Duysen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
33
Lockridge, Oksana
9
Li, Bin
6
Birt, Diane
5
Yaktine, AL
4
Levey, Allan
4
Schopfer, Lawrence
3
Kiewert, Cornelia
3
Hartmann, Joachim
3
Klein, Jochen
3
Volpicelli-Daley, Laura
3
Wang, Weiqun
2
Murrin, Leonard
2
Thompson, Charles
2
Hinrichs, Steven
2
Hrabovska, Anna

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Publications

TOP 3
Grigoryan Hasmik; Schopfer Lawrence M; Peeples Eric S; Duysen Ellen G; Grigoryan Marine; Thompson Charles M; Lockridge Oksana
Mass spectrometry identifies multiple organophosphorylated sites on tubulin.
Chilukuri Nageswararao; Duysen Ellen G; Parikh Kalpana; diTargiani Robert; Doctor Bhupendra P; Lockridge Oksana; Saxena Ashima
Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents.
Johnson Noel D; Duysen Ellen G; Lockridge Oksana
Intrathecal delivery of fluorescent labeled butyrylcholinesterase to the brains of butyrylcholinesterase knock-out mice: visualization and quantification of enzyme distribution in the brain.

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All Publications

2009: Grigoryan Hasmik; Schopfer Lawrence M; Peeples Eric S; Duysen Ellen G; Grigoryan Marine; Thompson Charles M; Lockridge Oksana
Mass spectrometry identifies multiple organophosphorylated sites on tubulin.
Toxicology and applied pharmacology 2009;240(2):149-58.
2009: Chilukuri Nageswararao; Duysen Ellen G; Parikh Kalpana; diTargiani Robert; Doctor Bhupendra P; Lockridge Oksana; Saxena Ashima
Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents.
Molecular pharmacology 2009;76(3):612-7.
2009: Johnson Noel D; Duysen Ellen G; Lockridge Oksana
Intrathecal delivery of fluorescent labeled butyrylcholinesterase to the brains of butyrylcholinesterase knock-out mice: visualization and quantification of enzyme distribution in the brain.
Neurotoxicology 2009;30(3):386-92.
2009: Duysen Ellen G; Li Bin; Lockridge Oksana
The butyrylcholinesterase knockout mouse a research tool in the study of drug sensitivity, bio-distribution, obesity and Alzheimer's disease.
Expert opinion on drug metabolism & toxicology 2009;5(5):523-8.
2009: Naik Runa S; Hartmann Joachim; Kiewert Cornelia; Duysen Ellen G; Lockridge Oksana; Klein Jochen
Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 2009;12(1):79-85.
2008: Duysen Ellen G; Li Bin; Carlson Michaela; Li Yi-Fan; Wieseler Stacy; Hinrichs Steven H; Lockridge Oksana
Increased hepatotoxicity and cardiac fibrosis in cocaine-treated butyrylcholinesterase knockout mice.
Basic & clinical pharmacology & toxicology 2008;103(6):514-21.
2008: Chilukuri Nageswararao; Duysen Ellen G; Parikh Kalpana; Sun Wei; Doctor Bhupendra P; Lockridge Oksana; Saxena Ashima
Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo.
Chemico-biological interactions 2008;175(1-3):327-31.
2008: Duysen Ellen G; Lockridge Oksana
Whole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesterase.
Chemico-biological interactions 2008;175(1-3):119-24.
2008: Li Bin; Duysen Ellen G; Lockridge Oksana
The butyrylcholinesterase knockout mouse is obese on a high-fat diet.
Chemico-biological interactions 2008;175(1-3):88-91.
2008: Hartmann Joachim; Kiewert Cornelia; Duysen Ellen G; Lockridge Oksana; Klein Jochen
Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice.
Neurochemistry international 2008;52(6):972-8.
2008: Li Bin; Duysen Ellen G; Carlson Michaela; Lockridge Oksana
The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency.
The Journal of pharmacology and experimental therapeutics 2008;324(3):1146-54.
2007: Myslivecek Jaromir; Duysen Ellen G; Lockridge Oksana
Adaptation to excess acetylcholine by downregulation of adrenoceptors and muscarinic receptors in lungs of acetylcholinesterase knockout mice.
Naunyn-Schmiedeberg's archives of pharmacology 2007;376(1-2):83-92.
2007: Rice Stephen G; Nowak Lee; Duysen Ellen G; Lockridge Oksana; Lahiri Debomoy K; Reyes Patricio F
Neuropathological and immunochemical studies of brain parenchyma in acetylcholinesterase knockout mice: implications in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2007;11(4):481-9.
2007: Duysen Ellen G; Li Bin; Darvesh Sultan; Lockridge Oksana
Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission.
Toxicology 2007;233(1-3):60-9.
2007: Hartmann Joachim; Kiewert Cornelia; Duysen Ellen G; Lockridge Oksana; Greig Nigel H; Klein Jochen
Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity.
Journal of neurochemistry 2007;100(5):1421-9.
2006: Li Bin; Duysen Ellen G; Poluektova Larisa Y; Murrin L Charles; Lockridge Oksana
Protection from the toxicity of diisopropylfluorophosphate by adeno-associated virus expressing acetylcholinesterase.
Toxicology and applied pharmacology 2006;214(2):152-65.
2006: Li Bin; Duysen Ellen G; Saunders Thomas L; Lockridge Oksana
Production of the butyrylcholinesterase knockout mouse.
Journal of molecular neuroscience : MN 2006;30(1-2):193-5.
2006: Duysen Ellen G; Lockridge Oksana
Phenotype comparison of three acetylcholinesterase knockout strains.
Journal of molecular neuroscience : MN 2006;30(1-2):91-2.
2006: Li Bin; Duysen Ellen G; Lockridge Oksana
Gene transfer of acetylcholinesterase protects the knockout mouse from the toxicity of DFP.
Journal of molecular neuroscience : MN 2006;30(1-2):79-80.
2005: Hrabovska Anna; Duysen Ellen G; Sanders Jeffrey D; Murrin L Charles; Lockridge Oksana
Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse.
Chemico-biological interactions 2005;157-158():71-8.
2005: Li Bin; Sedlacek Meghan; Manoharan Indumathi; Boopathy Rathnam; Duysen Ellen G; Masson Patrick; Lockridge Oksana
Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma.
Biochemical pharmacology 2005;70(11):1673-84.
2005: Peeples Eric S; Schopfer Lawrence M; Duysen Ellen G; Spaulding Reggie; Voelker Troy; Thompson Charles M; Lockridge Oksana
Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry.
Toxicological sciences : an official journal of the Society of Toxicology 2005;83(2):303-12.
2004: Adler Michael; Manley Heather A; Purcell Angela L; Deshpande Sharad S; Hamilton Tracey A; Kan Robert K; Oyler George; Lockridge Oksana; Duysen Ellen G; Sheridan Robert E
Reduced acetylcholine receptor density, morphological remodeling, and butyrylcholinesterase activity can sustain muscle function in acetylcholinesterase knockout mice.
Muscle & nerve 2004;30(3):317-27.
2004: Wang Yuxia; Schopfer Lawrence M; Duysen Ellen G; Nachon Florian; Masson Patrick; Lockridge Oksana
Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants.
Analytical biochemistry 2004;329(1):131-8.
2004: Wang Yuxia; Boeck Andreea Ticu; Duysen Ellen G; Van Keuren Margaret; Saunders Thomas L; Lockridge Oksana
Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase.
Toxicology and applied pharmacology 2004;196(3):356-66.
2003: Volpicelli-Daley Laura A; Hrabovska Anna; Duysen Ellen G; Ferguson Shawn M; Blakely Randy D; Lockridge Oksana; Levey Allan I
Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice.
Molecular pharmacology 2003;64(6):1309-16.
2003: Volpicelli-Daley Laura A; Duysen Ellen G; Lockridge Oksana; Levey Allan I
Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice.
Annals of neurology 2003;53(6):788-96.
2003: Li Bin; Duysen Ellen G; Volpicelli-Daley Laura A; Levey Allan I; Lockridge Oksana
Regulation of muscarinic acetylcholine receptor function in acetylcholinesterase knockout mice.
Pharmacology, biochemistry, and behavior 2003;74(4):977-86.
2002: Duysen Ellen Gail; Fry Debra Lucie; Lockridge Oksana
Early weaning and culling eradicated Helicobacter hepaticus from an acetylcholinesterase knockout 129S6/SvEvTac mouse colony.
Comparative medicine 2002;52(5):461-6.
2002: Duysen Ellen G; Bartels Cynthia F; Lockridge Oksana
Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity.
The Journal of pharmacology and experimental therapeutics 2002;302(2):751-8.
2002: Duysen Ellen G; Stribley Judith A; Fry Debra L; Hinrichs Steven H; Lockridge Oksana
Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet; phenotype of the adult acetylcholinesterase deficient mouse.
Brain research. Developmental brain research 2002;137(1):43-54.
2002: Mesulam M-M; Guillozet A; Shaw P; Levey A; Duysen E G; Lockridge O
Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine.
Neuroscience 2002;110(4):627-39.
2001: Duysen E G; Li B; Xie W; Schopfer L M; Anderson R S; Broomfield C A; Lockridge O
Evidence for nonacetylcholinesterase targets of organophosphorus nerve agent: supersensitivity of acetylcholinesterase knockout mouse to VX lethality.
The Journal of pharmacology and experimental therapeutics 2001;299(2):528-35.
2001: Przybyszewski J; Yaktine A L; Duysen E; Blackwood D; Wang W; Au A; Birt D F
Inhibition of phorbol ester-induced AP-1-DNA binding, c-Jun protein and c-jun mRNA by dietary energy restriction is reversed by adrenalectomy in SENCAR mouse epidermis.
Carcinogenesis 2001;22(9):1421-7.
2001: Birt D F; Duysen E; Wang W; Yaktine A
Corticosterone supplementation reduced selective protein kinase C isoform expression in the epidermis of adrenalectomized mice.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(6):679-85.
2001: Liu Y; Duysen E; Yaktine A L; Au A; Wang W; Birt D F
Dietary energy restriction inhibits ERK but not JNK or p38 activity in the epidermis of SENCAR mice.
Carcinogenesis 2001;22(4):607-12.
1999: Birt D F; Yaktine A; Duysen E
Glucocorticoid mediation of dietary energy restriction inhibition of mouse skin carcinogenesis.
The Journal of nutrition 1999;129(2S Suppl):571S-574S.
1998: Yaktine A L; Vaughn R; Blackwood D; Duysen E; Birt D F
Dietary energy restriction in the SENCAR mouse: elevation of glucocorticoid hormone levels but no change in distribution of glucocorticoid receptor in epidermal cells.
Molecular carcinogenesis 1998;21(1):62-9.
1997: Birt D F; Pour P M; Nagel D L; Barnett T; Blackwood D; Duysen E
Dietary energy restriction does not inhibit pancreatic carcinogenesis by N-nitrosobis-2-(oxopropyl)amine in the Syrian hamster.
Carcinogenesis 1997;18(11):2107-11.

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