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Michael Kuhar

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
64
carroll, Frank
31
Snyder, Solomon
28
Lewin, Anita
27
Abraham, Philip
26
Uhl, George
20
Dannals, Robert
17
Wong, Dean
15
Scheffel, Ursula
14
Hunter, Richard
13
Vicentic, Aleksandra
13
Wagner, Henry
11
Murrin, Leonard
10
Vaughan, Roxanne
10
Dominguez, Geraldina
10
Kimmel, Heather

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Publications

TOP 3
Kuhar Michael J
Blacklisting among scientists.
Jones D C; Lakatos A; Rogge G A; Kuhar M J
Regulation of cocaine- and amphetamine-regulated transcript mRNA expression by calcium-mediated signaling in GH3 cells.
Kuhar Michael J
On the use of protein turnover and half-lives.

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All Publications

2009: Kuhar Michael J
Blacklisting among scientists.
Synapse (New York, N.Y.) 2009;63(7):539-40.
2009: Jones D C; Lakatos A; Rogge G A; Kuhar M J
Regulation of cocaine- and amphetamine-regulated transcript mRNA expression by calcium-mediated signaling in GH3 cells.
Neuroscience 2009;160(2):339-47.
2009: Kuhar Michael J
On the use of protein turnover and half-lives.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(5):1172-3.
2009: Rogge George A; Jones Douglas C; Green Thomas; Nestler Eric; Kuhar Michael J
Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo.
Brain research 2009;1251():42-52.
2008: Rogge G; Jones D; Hubert G W; Lin Y; Kuhar M J
CART peptides: regulators of body weight, reward and other functions.
Nature reviews. Neuroscience 2008;9(10):747-58.
2008: Kuhar Michael J
On blacklisting in science.
Science and engineering ethics 2008;14(3):301-3.
2008: Francis D D; Kuhar M J
Frequency of maternal licking and grooming correlates negatively with vulnerability to cocaine and alcohol use in rats.
Pharmacology, biochemistry, and behavior 2008;90(3):497-500.
2008: Lima F B; Henderson J A; Reddy A P; Tokuyama Y; Hubert G W; Kuhar M J; Bethea C L
Unique responses of midbrain CART neurons in macaques to ovarian steroids.
Brain research 2008;1227():76-88.
2008: Jaworski Jason N; Hansen Stephen T; Kuhar Michael J; Mark Gregory P
Injection of CART (cocaine- and amphetamine-regulated transcript) peptide into the nucleus accumbens reduces cocaine self-administration in rats.
Behavioural brain research 2008;191(2):266-71.
2008: Hubert G W; Kuhar M J
Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos.
Neuropeptides 2008;42(3):339-43.
2008: Bartell S M; Isales C M; Baile C A; Kuhar M J; Hamrick M W
CART deficiency increases body weight but does not alter bone strength.
Journal of musculoskeletal & neuronal interactions 2008;8(2):146-53.
2008: Keating Glenda L; Kuhar Michael J; Rye David B
High dose CART peptide induces abnormal EEG activity and behavioral seizures.
Neuropeptides 2008;42(2):199-204.
2008: Jones Douglas C; Kuhar Michael J
CART receptor binding in primary cell cultures of the rat nucleus accumbens.
Synapse (New York, N.Y.) 2008;62(2):122-7.
2008: van der Burg Jorien M M; Bacos Karl; Wood Nigel I; Lindqvist Andreas; Wierup Nils; Woodman Ben; Wamsteeker Jaclyn I; Smith Ruben; Deierborg Tomas; Kuhar Michael J; Bates Gillian P; Mulder Hindrik; Erlanson-Albertsson Charlotte; Morton A Jennifer; Brundin Patrik; Petersén Asa; Björkqvist Maria
Increased metabolism in the R6/2 mouse model of Huntington's disease.
Neurobiology of disease 2008;29(1):41-51.
2008: Hubert George W; Jones Douglas C; Moffett Mark C; Rogge George; Kuhar Michael J
CART peptides as modulators of dopamine and psychostimulants and interactions with the mesolimbic dopaminergic system.
Biochemical pharmacology 2008;75(1):57-62.
2007: Gong Paul K; Blough Bruce E; Brieaddy Lawrence E; Huang Xiaodong; Kuhar Michael J; Navarro Hernán A; Carroll F Ivy
Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.
Journal of medicinal chemistry 2007;50(15):3686-95.
2007: Gozen Oguz; Balkan Burcu; Yararbas Gorkem; Koylu Ersin O; Kuhar Michael J; Pogun Sakire
Sex differences in the regulation of cocaine and amphetamine-regulated transcript expression in hypothalamic nuclei of rats by forced swim stress.
Synapse (New York, N.Y.) 2007;61(7):561-8.
2007: Gunnarsdóttir A; Wierup N; Larsson L T; Kuhar M J; Ekblad E
CART-peptide immunoreactivity in enteric nerves in patients with Hirschsprung's disease.
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie 2007;17(3):184-9.
2007: Jaworski Jason N; Kimmel Heather L; Mitrano Darlene A; Tallarida Ronald J; Kuhar Michael J
Intra-VTA CART 55-102 reduces the locomotor effect of systemic cocaine in rats: an isobolographic analysis.
Neuropeptides 2007;41(2):65-72.
2007: Moffett M C; Vicentic A; Kozel Marie; Plotsky Paul; Francis D D; Kuhar M J
Maternal separation alters drug intake patterns in adulthood in rats.
Biochemical pharmacology 2007;73(3):321-30.
2006: Carroll F Ivy; Fox Barbara S; Kuhar Michael J; Howard James L; Pollard Gerald T; Schenk Susan
Effects of dopamine transporter selective 3-phenyltropane analogs on locomotor activity, drug discrimination, and cocaine self-administration after oral administration.
European journal of pharmacology 2006;553(1-3):149-56.
2006: Hubert George W; Kuhar Michael J
Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens.
Neuropeptides 2006;40(6):409-15.
2006: Koylu Ersin O; Balkan Burcu; Kuhar Michael J; Pogun Sakire
Cocaine and amphetamine regulated transcript (CART) and the stress response.
Peptides 2006;27(8):1956-69.
2006: Damaj M Imad; Zheng Jianfeng; Martin Billy R; Kuhar Michael J
Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain.
Peptides 2006;27(8):2019-23.
2006: Moffett Mark; Stanek Lisa; Harley Jill; Rogge George; Asnicar Mark; Hsiung Hansen; Kuhar Michael
Studies of cocaine- and amphetamine-regulated transcript (CART) knockout mice.
Peptides 2006;27(8):2037-45.
2006: Kuhar Michael J
Should Codes of Ethics include expectations of others?
Science and engineering ethics 2006;12(3):413-4.
2006: Balkan Burcu; Gozen Oguz; Yararbas Gorkem; Koylu Ersin O; Akinturk Serra; Kuhar Michael J; Pogun Sakire
CART expression in limbic regions of rat brain following forced swim stress: sex differences.
Neuropeptides 2006;40(3):185-93.
2006: Vicentic A; Francis D; Moffett M; Lakatos A; Rogge G; Hubert G W; Harley J; Kuhar M J
Maternal separation alters serotonergic transporter densities and serotonergic 1A receptors in rat brain.
Neuroscience 2006;140(1):355-65.
2006: Moffett Mark C; Harley Jill; Francis Darlene; Sanghani Sonal P; Davis Wilhelmina I; Kuhar Michael J
Maternal separation and handling affects cocaine self-administration in both the treated pups as adults and the dams.
The Journal of pharmacology and experimental therapeutics 2006;317(3):1210-8.
2006: Hunter Richard G; Jones Douglas; Vicentic Aleksandra; Hue Gillian; Rye David; Kuhar Michael J
Regulation of CART mRNA in the rat nucleus accumbens via D3 dopamine receptors.
Neuropharmacology 2006;50(7):858-64.
2006: Joyce Andrew R; Easterling Keith; Holtzman Stephen G; Kuhar Michael J
Modeling the onset of drug dependence: a consideration of the requirement for protein synthesis.
Journal of theoretical biology 2006;240(4):531-7.
2006: Jones Douglas C; Kuhar Michael J
Cocaine-amphetamine-regulated transcript expression in the rat nucleus accumbens is regulated by adenylyl cyclase and the cyclic adenosine 5'-monophosphate/protein kinase a second messenger system.
The Journal of pharmacology and experimental therapeutics 2006;317(1):454-61.
2006: Wierup Nils; Björkqvist Maria; Kuhar Michael J; Mulder Hindrik; Sundler Frank
CART regulates islet hormone secretion and is expressed in the beta-cells of type 2 diabetic rats.
Diabetes 2006;55(2):305-11.
2006: Yanik Tulin; Dominguez Geraldina; Kuhar Michael J; Del Giudice Emanuele M; Loh Y Peng
The Leu34Phe ProCART mutation leads to cocaine- and amphetamine-regulated transcript (CART) deficiency: a possible cause for obesity in humans.
Endocrinology 2006;147(1):39-43.
2006: Carroll F Ivy; Howard James L; Howell Leonard L; Fox Barbara S; Kuhar Michael J
Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse.
The AAPS journal 2006;8(1):E196-203.
2006: Miraglia del Giudice E; Santoro N; Fiumani P; Dominguez G; Kuhar M J; Perrone L
Adolescents carrying a missense mutation in the CART gene exhibit increased anxiety and depression.
Depression and anxiety 2006;23(2):90-2.
2005: Hemby Scott E; Tang Wenxue; Muly Emil C; Kuhar Michael J; Howell Leonard; Mash Deborah C
Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates.
Journal of neurochemistry 2005;95(6):1785-93.
2005: Vicentic Aleksandra; Lakatos Anita; Kuhar Michael J
CART (cocaine- and amphetamine-regulated transcript) peptide receptors: specific binding in AtT20 cells.
European journal of pharmacology 2005;528(1-3):188-9.
2005: Kotturi Sharadsrikar V; Jiang Songchun; Chang An-Chih; Abraham Philip; Navarro Hernán A; Kuhar Michael J; Carroll F Ivy
Synthesis and monoamine transporter binding properties of 2,3-diaryltropanes.
Journal of medicinal chemistry 2005;48(23):7437-44.
2005: Lakatos Anita; Prinster Steven; Vicentic Aleksandra; Hall Randy A; Kuhar Michael J
Cocaine- and amphetamine-regulated transcript (CART) peptide activates the extracellular signal-regulated kinase (ERK) pathway in AtT20 cells via putative G-protein coupled receptors.
Neuroscience letters 2005;384(1-2):198-202.
2005: Jaworski J N; Francis D D; Brommer C L; Morgan E T; Kuhar M J
Effects of early maternal separation on ethanol intake, GABA receptors and metabolizing enzymes in adult rats.
Psychopharmacology 2005;181(1):8-15.
2005: Hubert George W; Kuhar Michael J
Colocalization of CART with substance P but not enkephalin in the rat nucleus accumbens.
Brain research 2005;1050(1-2):8-14.
2005: Hunter Richard G; Vicentic Aleksandra; Rogge George; Kuhar Michael J
The effects of cocaine on CART expression in the rat nucleus accumbens: a possible role for corticosterone.
European journal of pharmacology 2005;517(1-2):45-50.
2005: Wierup N; Richards W G; Bannon A W; Kuhar M J; Ahrén B; Sundler F
CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight.
Regulatory peptides 2005;129(1-3):203-11.
2005: Hunter Richard G; Lim Miranda M; Philpot Kelly B; Young Larry J; Kuhar Michael J
Species differences in brain distribution of CART mRNA and CART peptide between prairie and meadow voles.
Brain research 2005;1048(1-2):12-23.
2005: Carroll F Ivy; Tyagi Sameer; Blough Bruce E; Kuhar Michael J; Navarro Hernn A
Synthesis and monoamine transporter binding properties of 3alpha-(substituted phenyl)nortropane-2beta-carboxylic acid methyl esters. Norepinephrine transporter selective compounds.
Journal of medicinal chemistry 2005;48(11):3852-7.
2005: Carroll F Ivy; Blough Bruce E; Nie Zhe; Kuhar Michael J; Howell Leonard L; Navarro Hernan A
Synthesis and monoamine transporter binding properties of 3beta-(3',4'-disubstituted phenyl)tropane-2beta-carboxylic acid methyl esters.
Journal of medicinal chemistry 2005;48(8):2767-71.
2005: Runyon Scott P; Burgess Jason P; Abraham Philip; Keverline-Frantz Kathryn I; Flippen-Anderson Judy; Deschamps Jeffrey; Lewin Anita H; Navarro Hernán A; Boja John W; Kuhar Michael J; Carroll F Ivy
Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product.
Bioorganic & medicinal chemistry 2005;13(7):2439-49.
2005: Vicentic A; Hunter R G; Kuhar M J
Effect of corticosterone on CART peptide levels in rat blood.
Peptides 2005;26(3):531-3.
2005: Vicentic Aleksandra; Lakatos Anita; Hunter Richard; Philpot Kelly; Dominguez Geraldina; Kuhar Michael J
CART peptide diurnal rhythm in brain and effect of fasting.
Brain research 2005;1032(1-2):111-5.
2005: Philpot K B; Dallvechia-Adams S; Smith Y; Kuhar M J
A cocaine-and-amphetamine-regulated-transcript peptide projection from the lateral hypothalamus to the ventral tegmental area.
Neuroscience 2005;135(3):915-25.
2005: Kuhar Michael J; Jaworski Jason N; Hubert George W; Philpot Kelly B; Dominguez Geraldina
Cocaine- and amphetamine-regulated transcript peptides play a role in drug abuse and are potential therapeutic targets.
The AAPS journal 2005;7(1):E259-65.
2005: Osei-Hyiaman Douglas; Depetrillo Michael; Harvey-White Judith; Bannon Anthony W; Cravatt Benjamin F; Kuhar Michael J; Mackie Ken; Palkovits Miklós; Kunos George
Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide.
Neuroendocrinology 2005;81(4):273-82.
2004: Carroll F Ivy; Runyon Scott P; Abraham Philip; Navarro Hernan; Kuhar Michael J; Pollard Gerald T; Howard James L
Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers.
Journal of medicinal chemistry 2004;47(25):6401-9.
2004: Dominguez G; del Giudice E M; Kuhar M J
CART peptide levels are altered by a mutation associated with obesity at codon 34.
Molecular psychiatry 2004;9(12):1065-6.
2004: Hunter Richard G; Philpot Kelly; Vicentic Aleksandra; Dominguez Geraldina; Hubert George W; Kuhar Michael J
CART in feeding and obesity.
Trends in endocrinology and metabolism: TEM 2004;15(9):454-9.
2004: Dominguez Geraldina; Vicentic Alexandra; Del Giudice Emanuele Miraglia; Jaworski Jason; Hunter Richard G; Kuhar Michael J
CART peptides: modulators of mesolimbic dopamine, feeding, and stress.
Annals of the New York Academy of Sciences 2004;1025():363-9.
2004: Damaj M Imad; Hunter Richard G; Martin Billy R; Kuhar Michael J
Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice.
Brain research 2004;1024(1-2):146-9.
2004: Choi Yang-Ho; Della-Fera Mary Anne; Li ChangLong; Hartzell Diane L; Little Dianne E; Kuhar Michael J; Baile Clifton A
CART peptide: central mediator of leptin-induced adipose tissue apoptosis?
Regulatory peptides 2004;121(1-3):155-62.
2004: Vicentic A; Dominguez G; Hunter R G; Philpot K; Wilson M; Kuhar M J
Cocaine- and amphetamine-regulated transcript peptide levels in blood exhibit a diurnal rhythm: regulation by glucocorticoids.
Endocrinology 2004;145(9):4119-24.
2004: Dominguez Geraldina; Kuhar Michael J
Transcriptional regulation of the CART promoter in CATH.a cells.
Brain research. Molecular brain research 2004;126(1):22-9.
2004: Kuriyama Genshin; Takekoshi Susumu; Tojo Katsuyoshi; Nakai Yoshikatsu; Kuhar Michael J; Osamura R Yoshiyuki
Cocaine- and amphetamine-regulated transcript peptide in the rat anterior pituitary gland is localized in gonadotrophs and suppresses prolactin secretion.
Endocrinology 2004;145(5):2542-50.
2004: Wierup N; Kuhar M; Nilsson B O; Mulder H; Ekblad E; Sundler F
Cocaine- and amphetamine-regulated transcript (CART) is expressed in several islet cell types during rat development.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2004;52(2):169-77.
2004: Carroll F Ivy; Pawlush Neil; Kuhar Michael J; Pollard Gerald T; Howard James L
Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.
Journal of medicinal chemistry 2004;47(2):296-302.
2003: Jaworski Jason N; Kozel Marie A; Philpot Kelly B; Kuhar Michael J
Intra-accumbal injection of CART (cocaine-amphetamine regulated transcript) peptide reduces cocaine-induced locomotor activity.
The Journal of pharmacology and experimental therapeutics 2003;307(3):1038-44.
2003: Ekblad E; Kuhar M; Wierup N; Sundler F
Cocaine- and amphetamine-regulated transcript: distribution and function in rat gastrointestinal tract.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2003;15(5):545-57.
2003: Balkan Burcu; Koylu Ersin; Pogun Sakire; Kuhar Michael J
Effects of adrenalectomy on CART expression in the rat arcuate nucleus.
Synapse (New York, N.Y.) 2003;50(1):14-9.
2003: Damaj M Imad; Martin Billy R; Kuhar Michael J
Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice.
Brain research 2003;983(1-2):233-6.
2003: Kuhar M J; Joyce A R
Is the onset of psychoactive drug effects compatible with a protein-synthesis mechanism?
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28 Suppl 1():S94-7.
2003: Jaworski J N; Vicentic A; Hunter R G; Kimmel H L; Kuhar M J
CART peptides are modulators of mesolimbic dopamine and psychostimulants.
Life sciences 2003;73(6):741-7.
2003: Hunter Richard G; Kuhar Michael J
CART peptides as targets for CNS drug development.
Current drug targets. CNS and neurological disorders 2003;2(3):201-5.
2003: Kimmel Heather L; Carroll F Ivy; Kuhar Michael J
Withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum.
The Journal of pharmacology and experimental therapeutics 2003;304(1):15-21.
2002: Blough Bruce E; Keverline Kathryn I; Nie Zhe; Navarro Hernán; Kuhar Michael J; Carroll F Ivy
Synthesis and transporter binding properties of 3beta-[4'-(phenylalkyl, -phenylalkenyl, and -phenylalkynyl)phenyl]tropane-2beta-carboxylic acid methyl esters: evidence of a remote phenyl binding domain on the dopamine transporter.
Journal of medicinal chemistry 2002;45(18):4029-37.
2002: Lakatos A; Dominguez G; Kuhar M J
CART promoter CRE site binds phosphorylated CREB.
Brain research. Molecular brain research 2002;104(1):81-5.
2002: Dallvechia-Adams Stephanie; Kuhar Michael J; Smith Yoland
Cocaine- and amphetamine-regulated transcript peptide projections in the ventral midbrain: colocalization with gamma-aminobutyric acid, melanin-concentrating hormone, dynorphin, and synaptic interactions with dopamine neurons.
The Journal of comparative neurology 2002;448(4):360-72.
2002: Dominguez Geraldina; Lakatos Anita; Kuhar Michael J
Characterization of the cocaine- and amphetamine-regulated transcript (CART) peptide gene promoter and its activation by a cyclic AMP-dependent signaling pathway in GH3 cells.
Journal of neurochemistry 2002;80(5):885-93.
2002: Kimmel H L; Thim L; Kuhar M J
Activity of various CART peptides in changing locomotor activity in the rat.
Neuropeptides 2002;36(1):9-12.
2002: Kuhar M J; Adams S; Dominguez G; Jaworski J; Balkan B
CART peptides.
Neuropeptides 2002;36(1):1-8.
2002: Kuhar Michael J
Social rank and vulnerability to drug abuse.
Nature neuroscience 2002;5(2):88-90.
2001: Kimmel H L; Carroll F I; Kuhar M J
Locomotor stimulant effects of novel phenyltropanes in the mouse.
Drug and alcohol dependence 2001;65(1):25-36.
2001: Balkan B; Koylu E O; Kuhar M J; Pogun S
The effect of adrenalectomy on cocaine and amphetamine-regulated transcript (CART) expression in the hypothalamic nuclei of the rat.
Brain research 2001;917(1):15-20.
2001: Kuhar M J; Joyce A R
Slow onset of CNS drugs: can changes in protein concentration account for the delay?
Trends in pharmacological sciences 2001;22(9):450-6.
2001: Navarro H A; Xu H; Zhong D; Blough B E; Ross W P; Kuhar M J; Carroll F I
[(125)I]3beta-(4-ethyl-3-iodophenyl)nortropane-2beta-carboxylic acid methyl ester ([(125)I]EINT): a potent and selective radioligand for the brain serotonin transporter.
Synapse (New York, N.Y.) 2001;41(3):241-7.
2001: Wu Q; Reith M E; Kuhar M J; Carroll F I; Garris P A
Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(16):6338-47.
2001: Kuhar M J; Carroll F I; Bharat N; Landry D W
Anticocaine catalytic antibodies have no affinity for RTI compounds: implications for treatment.
Synapse (New York, N.Y.) 2001;41(2):176-8.
2001: Kimmel H L; Joyce A R; Carroll F I; Kuhar M J
Dopamine D1 and D2 receptors influence dopamine transporter synthesis and degradation in the rat.
The Journal of pharmacology and experimental therapeutics 2001;298(1):129-40.
2001: Aja S; Schwartz G J; Kuhar M J; Moran T H
Intracerebroventricular CART peptide reduces rat ingestive behavior and alters licking microstructure.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(6):R1613-9.
2001: Dallvechia-Adams S; Smith Y; Kuhar M J
CART peptide-immunoreactive projection from the nucleus accumbens targets substantia nigra pars reticulata neurons in the rat.
The Journal of comparative neurology 2001;434(1):29-39.
2001: Kuhar M J; Joyce A; Dominguez G
Genes in drug abuse.
Drug and alcohol dependence 2001;62(3):157-62.
2001: Kimmel H; Vicentic A; Kuhar M J
Neurotransmitter transporters synthesis and degradation rates.
Life sciences 2001;68(19-20):2181-5.
2001: Kimmel H L; Carroll F I; Kuhar M J
RTI-76, an irreversible inhibitor of dopamine transporter binding, increases locomotor activity in the rat at high doses.
Brain research 2001;897(1-2):157-63.
2001: Elias C F; Lee C E; Kelly J F; Ahima R S; Kuhar M; Saper C B; Elmquist J K
Characterization of CART neurons in the rat and human hypothalamus.
The Journal of comparative neurology 2001;432(1):1-19.
2001: Stanley S A; Small C J; Murphy K G; Rayes E; Abbott C R; Seal L J; Morgan D G; Sunter D; Dakin C L; Kim M S; Hunter R; Kuhar M; Ghatei M A; Bloom S R
Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats.
Brain research 2001;893(1-2):186-94.
2000: Fekete C; Mihály E; Luo L G; Kelly J; Clausen J T; Mao Q; Rand W M; Moss L G; Kuhar M; Emerson C H; Jackson I M; Lechan R M
Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(24):9224-34.
2000: Johansen J E; Broberger C; Lavebratt C; Johansson C; Kuhar M J; Hökfelt T; Schalling M
Hypothalamic CART and serum leptin levels are reduced in the anorectic (anx/anx) mouse.
Brain research. Molecular brain research 2000;84(1-2):97-105.
2000: Blough B E; Holmquist C R; Abraham P; Kuhar M J; Carroll F I
3alpha-(4-Substituted phenyl)nortropane-2beta-carboxylic acid methyl esters show selective binding at the norepinephrine transporter.
Bioorganic & medicinal chemistry letters 2000;10(21):2445-7.
2000: Wang L C; Berfield J L; Kuhar M J; Carroll F I; Reith M E
RTI-76, an isothiocyanate derivative of a phenyltropane cocaine analog, as a tool for irreversibly inactivating dopamine transporter function in vitro.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(3):238-47.
2000: Murphy K G; Abbott C R; Mahmoudi M; Hunter R; Gardiner J V; Rossi M; Stanley S A; Ghatei M A; Kuhar M J; Bloom S R
Quantification and synthesis of cocaine- and amphetamine-regulated transcript peptide (79-102)-like immunoreactivity and mRNA in rat tissues.
The Journal of endocrinology 2000;166(3):659-68.
2000: Kimmel H L; Gong W; Vechia S D; Hunter R G; Kuhar M J
Intra-ventral tegmental area injection of rat cocaine and amphetamine-regulated transcript peptide 55-102 induces locomotor activity and promotes conditioned place preference.
The Journal of pharmacology and experimental therapeutics 2000;294(2):784-92.
2000: Koylu E O; Weruaga E; Balkan B; Alonso J R; Kuhar M J; Pogun S
Co-localization of cart peptide immunoreactivity and nitric oxide synthase activity in rat hypothalamus.
Brain research 2000;868(2):352-7.
2000: Kuhar M J; Adams L D; Hunter R G; Vechia S D; Smith Y
CART peptides.
Regulatory peptides 2000;89(1-3):1-6.
2000: Kimmel H L; Carroll F I; Kuhar M J
Dopamine transporter synthesis and degradation rate in rat striatum and nucleus accumbens using RTI-76.
Neuropharmacology 2000;39(4):578-85.
2000: Howell L L; Czoty P W; Kuhar M J; Carrol F I
Comparative behavioral pharmacology of cocaine and the selective dopamine uptake inhibitor RTI-113 in the squirrel monkey.
The Journal of pharmacology and experimental therapeutics 2000;292(2):521-9.
2000: Dall Vechia S; Lambert P D; Couceyro P C; Kuhar M J; Smith Y
CART peptide immunoreactivity in the hypothalamus and pituitary in monkeys: analysis of ultrastructural features and synaptic connections in the paraventricular nucleus.
The Journal of comparative neurology 2000;416(3):291-308.
1999: Adams L D; Gong W; Vechia S D; Hunter R G; Kuhar M J
CART: from gene to function.
Brain research 1999;848(1-2):137-40.
1999: Javanmard S; Deutsch H M; Collard D M; Kuhar M J; Schweri M M
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.
Journal of medicinal chemistry 1999;42(23):4836-43.
1999: Broberger C; Visser T J; Kuhar M J; Hökfelt T
Neuropeptide Y innervation and neuropeptide-Y-Y1-receptor-expressing neurons in the paraventricular hypothalamic nucleus of the mouse.
Neuroendocrinology 1999;70(5):295-305.
1999: Broberger C; Holmberg K; Kuhar M J; Hökfelt T
Cocaine- and amphetamine-regulated transcript in the rat vagus nerve: A putative mediator of cholecystokinin-induced satiety.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13506-11.
1999: Vicentic A; Battaglia G; Carroll F I; Kuhar M J
Serotonin transporter production and degradation rates: studies with RTI-76.
Brain research 1999;841(1-2):1-10.
1999: Kuhar M J; Yoho L L
CART peptide analysis by Western blotting.
Synapse (New York, N.Y.) 1999;33(3):163-71.
1999: Kuhar M J; McGirr K M; Hunter R G; Lambert P D; Garrett B E; Carroll F I
Studies of selected phenyltropanes at monoamine transporters.
Drug and alcohol dependence 1999;56(1):9-15.
1999: Lambert P D; McGirr K M; Ely T D; Kilts C D; Kuhar M J
Chronic lithium treatment decreases neuronal activity in the nucleus accumbens and cingulate cortex of the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;21(2):229-37.
1999: Carroll F I; Howell L L; Kuhar M J
Pharmacotherapies for treatment of cocaine abuse: preclinical aspects.
Journal of medicinal chemistry 1999;42(15):2721-36.
1999: Garzón M; Vaughan R A; Uhl G R; Kuhar M J; Pickel V M
Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter.
The Journal of comparative neurology 1999;410(2):197-210.
1999: Kuhar M J; Dall Vechia S E
CART peptides: novel addiction- and feeding-related neuropeptides.
Trends in neurosciences 1999;22(7):316-20.
1999: Smith Y; Kieval J; Couceyro P R; Kuhar M J
CART peptide-immunoreactive neurones in the nucleus accumbens in monkeys: ultrastructural analysis, colocalization studies, and synaptic interactions with dopaminergic afferents.
The Journal of comparative neurology 1999;407(4):491-511.
1999: Koylu E O; Smith Y; Couceyro P R; Kuhar M J
CART peptides colocalize with tyrosine hydroxylase neurons in rat locus coeruleus.
Synapse (New York, N.Y.) 1999;31(4):309-11.
1999: Ding Y S; Molina P E; Fowler J S; Logan J; Volkow N D; Kuhar M J; Carroll F I
Comparative studies of epibatidine derivatives [18F]NFEP and [18F]N-methyl-NFEP: kinetics, nicotine effect, and toxicity.
Nuclear medicine and biology 1999;26(1):139-48.
1998: Jiang S; Chang A C; Abraham P; Kuhar M J; Carroll F I
Synthesis and transporter binding properties of (R)-2 beta, 3 beta- and (R)-2 alpha, 3 alpha-diaryltropanes.
Bioorganic & medicinal chemistry letters 1998;8(24):3689-92.
1998: Elias C F; Lee C; Kelly J; Aschkenasi C; Ahima R S; Couceyro P R; Kuhar M J; Saper C B; Elmquist J K
Leptin activates hypothalamic CART neurons projecting to the spinal cord.
Neuron 1998;21(6):1375-85.
1998: Dworkin S I; Lambert P; Sizemore G M; Carroll F I; Kuhar M J
RTI-113 administration reduces cocaine self-administration at high occupancy of dopamine transporter.
Synapse (New York, N.Y.) 1998;30(1):49-55.
1998: Boja J W; Carroll F I; Vaughan R A; Kopajtic T; Kuhar M J
Multiple binding sites for [125I]RTI-121 and other cocaine analogs in rat frontal cerebral cortex.
Synapse (New York, N.Y.) 1998;30(1):9-17.
1998: Couceyro P; Paquet M; Koylu E; Kuhar M J; Smith Y
Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in myenteric plexus neurons of the rat ileum and co-localization with choline acetyltransferase.
Synapse (New York, N.Y.) 1998;30(1):1-8.
1998: Lambert P D; Couceyro P R; McGirr K M; Dall Vechia S E; Smith Y; Kuhar M J
CART peptides in the central control of feeding and interactions with neuropeptide Y.
Synapse (New York, N.Y.) 1998;29(4):293-8.
1998: Koylu E O; Couceyro P R; Lambert P D; Kuhar M J
Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain.
The Journal of comparative neurology 1998;391(1):115-32.
1998: Persico A M; Reich S; Henningfield J E; Kuhar M J; Uhl G R
Parkinsonian patients report blunted subjective effects of methylphenidate.
Experimental and clinical psychopharmacology 1998;6(1):54-63.
1998: Keverline-Frantz K I; Boja J W; Kuhar M J; Abraham P; Burgess J P; Lewin A H; Carroll F I
Synthesis and ligand binding of tropane ring analogues of paroxetine.
Journal of medicinal chemistry 1998;41(2):247-57.
1998: Kuhar M J
Recent biochemical studies of the dopamine transporter--a CNS drug target.
Life sciences 1998;62(17-18):1573-5.
1998: Vaughan R A; Huff R A; Uhl G R; Kuhar M J
Phosphorylation of dopamine transporters and rapid adaptation to cocaine.
Advances in pharmacology (San Diego, Calif.) 1998;42():1042-5.
1998: Wong D F; Ricaurte G; Gründer G; Rothman R; Naidu S; Singer H; Harris J; Yokoi F; Villemagne V; Szymanski S; Gjedde A; Kuhar M
Dopamine transporter changes in neuropsychiatric disorders.
Advances in pharmacology (San Diego, Calif.) 1998;42():219-23.
1998: Kuhar M J; Vaughan R; Uhl G; Cerruti C; Revay R; Freed C; Nirenburg M; Pickel V
Localization of dopamine transporter protein by microscopic histochemistry.
Advances in pharmacology (San Diego, Calif.) 1998;42():168-70.
1997: Molina P E; Ding Y S; Carroll F I; Liang F; Volkow N D; Pappas N; Kuhar M; Abumrad N; Gatley S J; Fowler J S
Fluoro-norchloroepibatidine: preclinical assessment of acute toxicity.
Nuclear medicine and biology 1997;24(8):743-7.
1997: Koylu E O; Couceyro P R; Lambert P D; Ling N C; DeSouza E B; Kuhar M J
Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland.
Journal of neuroendocrinology 1997;9(11):823-33.
1997: Blough B E; Abraham P; Mills A C; Lewin A H; Boja J W; Scheffel U; Kuhar M J; Carroll F I
3 Beta-(4-ethyl-3-iodophenyl)nortropane-2 beta-carboxylic acid methyl ester as a high-affinity selective ligand for the serotonin transporter.
Journal of medicinal chemistry 1997;40(24):3861-4.
1997: Nirenberg M J; Chan J; Pohorille A; Vaughan R A; Uhl G R; Kuhar M J; Pickel V M
The dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(18):6899-907.
1997: Smith Y; Koylu E O; Couceyro P; Kuhar M J
Ultrastructural localization of CART (cocaine- and amphetamine-regulated transcript) peptides in the nucleus accumbens of monkeys.
Synapse (New York, N.Y.) 1997;27(1):90-4.
1997: Couceyro P; Shoaib M; McCoy M; Goldberg S R; Kuhar M J
Cocaine self-administration alters brain NADH dehydrogenase mRNA levels.
Neuroreport 1997;8(11):2437-41.
1997: Liang F; Navarro H A; Abraham P; Kotian P; Ding Y S; Fowler J; Volkow N; Kuhar M J; Carroll F I
Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: a new positron emission tomography ligand for nicotinic receptors.
Journal of medicinal chemistry 1997;40(15):2293-5.
1997: Nirenberg M J; Chan J; Vaughan R A; Uhl G R; Kuhar M J; Pickel V M
Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(14):5255-62.
1997: Vaughan R A; Huff R A; Uhl G R; Kuhar M J
Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes.
The Journal of biological chemistry 1997;272(24):15541-6.
1997: Nirenberg M J; Chan J; Vaughan R A; Uhl G R; Kuhar M J; Pickel V M
Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(11):4037-44.
1997: Couceyro P R; Koylu E O; Kuhar M J
Further studies on the anatomical distribution of CART by in situ hybridization.
Journal of chemical neuroanatomy 1997;12(4):229-41.
1997: Chang A C; Burgess J P; Mascarella S W; Abraham P; Kuhar M J; Carroll F I
Synthesis and transporter binding properties of 2,3-diphenyltropane stereoisomers. Comparison to 3beta-phenyltropane-2beta-carboxylic acid esters.
Journal of medicinal chemistry 1997;40(8):1247-51.
1997: Zhan Y; Saindane A M; Scheffel U; Carroll F I; Holmquist C R; Kepler J A; Taylor G F; Kuhar M J
RTI-352: a 3 alpha analogue of RTI-55 as an in vivo dopamine transporter binding ligand.
Synapse (New York, N.Y.) 1997;25(4):389-92.
1997: Scheffel U; Lever J R; Abraham P; Parham K R; Mathews W B; Kopajtic T; Carroll F I; Kuhar M J
N-substituted phenyltropanes as in vivo binding ligands for rapid imaging studies of the dopamine transporter.
Synapse (New York, N.Y.) 1997;25(4):345-9.
1997: Wong D F; Pearlson G D; Tune L E; Young L T; Meltzer C C; Dannals R F; Ravert H T; Reith J; Kuhar M J; Gjedde A
Quantification of neuroreceptors in the living human brain: IV. Effect of aging and elevations of D2-like receptors in schizophrenia and bipolar illness.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(3):331-42.
1997: Huff R A; Vaughan R A; Kuhar M J; Uhl G R
Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax.
Journal of neurochemistry 1997;68(1):225-32.
1996: Ding Y S; Gatley S J; Fowler J S; Volkow N D; Aggarwal D; Logan J; Dewey S L; Liang F; Carroll F I; Kuhar M J
Mapping nicotinic acetylcholine receptors with PET.
Synapse (New York, N.Y.) 1996;24(4):403-7.
1996: Houlihan W J; Boja J W; Parrino V A; Kopajtic T A; Kuhar M J
Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.
Journal of medicinal chemistry 1996;39(25):4935-41.
1996: Holmquist C R; Keverline-Frantz K I; Abraham P; Boja J W; Kuhar M J; Carroll F I
3 alpha-(4'-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters: novel ligands with high affinity and selectivity at the dopamine transporter.
Journal of medicinal chemistry 1996;39(21):4139-41.
1996: Fleckenstein A E; Pögün S; Carroll F I; Kuhar M J
Recovery of dopamine transporter binding and function after intrastriatal administration of the irreversible inhibitor RTI-76 [3 beta-(3p-chlorophenyl) tropan-2 beta-carboxylic acid p-isothiocyanatophenylethyl ester hydrochloride].
The Journal of pharmacology and experimental therapeutics 1996;279(1):200-6.
1996: Fleckenstein A E; Kopajtic T A; Boja J W; Carroll F I; Kuhar M J
Highly potent cocaine analogs cause long-lasting increases in locomotor activity.
European journal of pharmacology 1996;311(2-3):109-14.
1996: Blough B E; Abraham P; Lewin A H; Kuhar M J; Boja J W; Carroll F I
Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.
Journal of medicinal chemistry 1996;39(20):4027-35.
1996: Vaughan R A; Kuhar M J
Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis.
The Journal of biological chemistry 1996;271(35):21672-80.
1996: Kuhar M J; Pilotte N S
Neurochemical changes in cocaine withdrawal.
Trends in pharmacological sciences 1996;17(7):260-4.
1996: Kotian P; Mascarella S W; Abraham P; Lewin A H; Boja J W; Kuhar M J; Carroll F I
Synthesis, ligand binding, and quantitative structure-activity relationship study of 3 beta-(4'-substituted phenyl)-2 beta-heterocyclic tropanes: evidence for an electrostatic interaction at the 2 beta-position.
Journal of medicinal chemistry 1996;39(14):2753-63.
1996: Scheffel U; Steinert C; Kim S E; Ehlers M D; Boja J W; Kuhar M J
Effect of dopaminergic drugs on the in vivo binding of [3H]WIN 35,428 to central dopamine transporters.
Synapse (New York, N.Y.) 1996;23(2):61-9.
1996: Vaughan R A; Brown V L; McCoy M T; Kuhar M J
Species- and brain region-specific dopamine transporters: immunological and glycosylation characteristics.
Journal of neurochemistry 1996;66(5):2146-52.
1996: Wong D F; Harris J C; Naidu S; Yokoi F; Marenco S; Dannals R F; Ravert H T; Yaster M; Evans A; Rousset O; Bryan R N; Gjedde A; Kuhar M J; Breese G R
Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5539-43.
1996: Hume S P; Luthra S K; Brown D J; Opacka-Juffry J; Osman S; Ashworth S; Myers R; Brady F; Carroll F I; Kuhar M J; Brooks D J
Evaluation of [11C]RTI-121 as a selective radioligand for PET studies of the dopamine transporter.
Nuclear medicine and biology 1996;23(3):377-84.
1996: Lever J R; Scheffel U; Stathis M; Seltzman H H; Wyrick C D; Abraham P; Parham K; Thomas B F; Boja J W; Kuhar M J; Carroll F I
Synthesis and in vivo studies of a selective ligand for the dopamine transporter: 3 beta-(4-[125I]iodophenyl) tropan-2 beta-carboxylic acid isopropyl ester ([125I]RTI-121).
Nuclear medicine and biology 1996;23(3):277-84.
1996: Revay R; Vaughan R; Grant S; Kuhar M J
Dopamine transporter immunohistochemistry in median eminence, amygdala, and other areas of the rat brain.
Synapse (New York, N.Y.) 1996;22(2):93-9.
1996: Gatley S J; Volkow N D; Chen R; Fowler J S; Carroll F I; Kuhar M J
Displacement of RTI-55 from the dopamine transporter by cocaine.
European journal of pharmacology 1996;296(2):145-51.
1996: Pilotte N S; Sharpe L G; Rountree S D; Kuhar M J
Cocaine withdrawal reduces dopamine transporter binding in the shell of the nucleus accumbens.
Synapse (New York, N.Y.) 1996;22(1):87-92.
1996: Nirenberg M J; Vaughan R A; Uhl G R; Kuhar M J; Pickel V M
The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(2):436-47.
1995: Scheffel U; Taylor G F; Kepler J A; Carroll F I; Kuhar M J
In vivo labeling of neuronal nicotinic acetylcholine receptors with radiolabeled isomers of norchloroepibatidine.
Neuroreport 1995;6(18):2483-8.
1995: Carroll F I; Scheffel U; Dannals R F; Boja J W; Kuhar M J
Development of imaging agents for the dopamine transporter.
Medicinal research reviews 1995;15(5):419-44.
1995: Kotian P; Abraham P; Lewin A H; Mascarella S W; Boja J W; Kuhar M J; Carroll F I
Synthesis and ligand binding study of 3 beta-(4'-substituted phenyl)-2 beta-(heterocyclic)tropanes.
Journal of medicinal chemistry 1995;38(18):3451-3.
1995: Freed C; Revay R; Vaughan R A; Kriek E; Grant S; Uhl G R; Kuhar M J
Dopamine transporter immunoreactivity in rat brain.
The Journal of comparative neurology 1995;359(2):340-9.
1995: Stathis M; Scheffel U; Lever S Z; Boja J W; Carroll F I; Kuhar M J
Rate of binding of various inhibitors at the dopamine transporter in vivo.
Psychopharmacology 1995;119(4):376-84.
1995: Carroll F I; Kotian P; Dehghani A; Gray J L; Kuzemko M A; Parham K A; Abraham P; Lewin A H; Boja J W; Kuhar M J
Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter.
Journal of medicinal chemistry 1995;38(2):379-88.
1994: Pögün S; Kuhar M J
Regulation of neurotransmitter reuptake by nitric oxide.
Annals of the New York Academy of Sciences 1994;738():305-15.
1994: Patel A P; Cerruti C; Vaughan R A; Kuhar M J
Developmentally regulated glycosylation of dopamine transporter.
Brain research. Developmental brain research 1994;83(1):53-8.
1994: Carroll F I; Mascarella S W; Kuzemko M A; Gao Y; Abraham P; Lewin A H; Boja J W; Kuhar M J
Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 beta-(3'-substituted phenyl)-, 3 beta-(4'-substituted phenyl)-, and 3 beta-(3',4'-disubstituted phenyl)tropane-2 beta-carboxylic acid methyl esters.
Journal of medicinal chemistry 1994;37(18):2865-73.
1994: Pogun S; Dawson V; Kuhar M J
Nitric oxide inhibits 3H-glutamate transport in synaptosomes.
Synapse (New York, N.Y.) 1994;18(1):21-6.
1994: Pilotte N S; Sharpe L G; Kuhar M J
Withdrawal of repeated intravenous infusions of cocaine persistently reduces binding to dopamine transporters in the nucleus accumbens of Lewis rats.
The Journal of pharmacology and experimental therapeutics 1994;269(3):963-9.
1994: Boja J W; Kuhar M J; Kopajtic T; Yang E; Abraham P; Lewin A H; Carroll F I
Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.
Journal of medicinal chemistry 1994;37(8):1220-3.
1994: Scheffel U; Kim S; Cline E J; Kuhar M J
Occupancy of the serotonin transporter by fluoxetine, paroxetine, and sertraline: in vivo studies with [125I]RTI-55.
Synapse (New York, N.Y.) 1994;16(4):263-8.
1994: Cerruti C; Pilotte N S; Uhl G; Kuhar M J
Reduction in dopamine transporter mRNA after cessation of repeated cocaine administration.
Brain research. Molecular brain research 1994;22(1-4):132-8.
1994: Pogun S; Baumann M H; Kuhar M J
Nitric oxide inhibits [3H]dopamine uptake.
Brain research 1994;641(1):83-91.
1994: Scheffel U; Dannals R F; Suehiro M; Ricaurte G A; Carroll F I; Kuhar M J; Wagner H N
Development of PET/SPECT ligands for the serotonin transporter.
NIDA research monograph 1994;138():111-30.
1993: Carroll F I; Gray J L; Abraham P; Kuzemko M A; Lewin A H; Boja J W; Kuhar M J
3-Aryl-2-(3'-substituted-1',2',4'-oxadiazol-5'-yl)tropane analogues of cocaine: affinities at the cocaine binding site at the dopamine, serotonin, and norepinephrine transporters.
Journal of medicinal chemistry 1993;36(20):2886-90.
1993: Brouard A; Pelaprat D; Boja J W; Carroll F I; Vial M; Kuhar M J; Rostene W
Potent cocaine analogs inhibit [3H]dopamine uptake in rat mesencephalic cells in primary cultures: pharmacological selectivity of embryonic cocaine sites.
Brain research. Developmental brain research 1993;75(1):13-7.
1993: Patel A; Uhl G; Kuhar M J
Species differences in dopamine transporters: postmortem changes and glycosylation differences.
Journal of neurochemistry 1993;61(2):496-500.
1993: Vaughan R A; Uhl G; Kuhar M J
Recognition of dopamine transporters by antipeptide antibodies.
Molecular and cellular neurosciences 1993;4(2):209-15.
1993: Cerruti C; Walther D M; Kuhar M J; Uhl G R
Dopamine transporter mRNA expression is intense in rat midbrain neurons and modest outside midbrain.
Brain research. Molecular brain research 1993;18(1-2):181-6.
1993: Carroll F I; Lewin A H; Kuhar M J; Boja J W
Cocaine receptor: a structure-activity relationship study.
NIDA research monograph 1993;134():229-37.
1993: Amara S G; Kuhar M J
Neurotransmitter transporters: recent progress.
Annual review of neuroscience 1993;16():73-93.
1993: Ritz M C; Kuhar M J
Psychostimulant drugs and a dopamine hypothesis regarding addiction: update on recent research.
Biochemical Society symposium 1993;59():51-64.
1992: Boja J W; McNeill R M; Lewin A H; Abraham P; Carroll F I; Kuhar M J
Selective dopamine transporter inhibition by cocaine analogs.
Neuroreport 1992;3(11):984-6.
1992: Scheffel U; Dannals R F; Wong D F; Yokoi F; Carroll F I; Kuhar M J
Dopamine transporter imaging with novel, selective cocaine analogs.
Neuroreport 1992;3(11):969-72.
1992: Cline E J; Scheffel U; Boja J W; Mitchell W M; Carroll F I; Abraham P; Lewin A H; Kuhar M J
In vivo binding of [125I]RTI-55 to dopamine transporters: pharmacology and regional distribution with autoradiography.
Synapse (New York, N.Y.) 1992;12(1):37-46.
1992: Boja J W; Mitchell W M; Patel A; Kopajtic T A; Carroll F I; Lewin A H; Abraham P; Kuhar M J
High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain.
Synapse (New York, N.Y.) 1992;12(1):27-36.
1992: Lew R; Patel A; Vaughan R A; Wilson A; Kuhar M J
Microheterogeneity of dopamine transporters in rat striatum and nucleus accumbens.
Brain research 1992;584(1-2):266-71.
1992: Rostène W; Boja J W; Scherman D; Carroll F I; Kuhar M J
Dopamine transport: pharmacological distinction between the synaptic membrane and the vesicular transporter in rat striatum.
European journal of pharmacology 1992;218(1):175-7.
1992: Boja J W; Cline E J; Carroll F I; Lewin A H; Philip A; Dannals R; Wong D; Scheffel U; Kuhar M J
High potency cocaine analogs: neurochemical, imaging, and behavioral studies.
Annals of the New York Academy of Sciences 1992;654():282-91.
1992: Carroll F I; Abraham P; Lewin A H; Parham K A; Boja J W; Kuhar M
Isopropyl and phenyl esters of 3 beta-(4-substituted phenyl)tropan-2 beta-carboxylic acids. Potent and selective compounds for the dopamine transporter.
Journal of medicinal chemistry 1992;35(13):2497-500.
1992: Scheffel U; Dannals R F; Cline E J; Ricaurte G A; Carroll F I; Abraham P; Lewin A H; Kuhar M J
[123/125I]RTI-55, an in vivo label for the serotonin transporter.
Synapse (New York, N.Y.) 1992;11(2):134-9.
1992: Carroll F I; Gao Y; Abraham P; Lewin A H; Lew R; Patel A; Boja J W; Kuhar M J
Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter.
Journal of medicinal chemistry 1992;35(10):1813-7.
1992: Carroll F I; Lewin A H; Boja J W; Kuhar M J
Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter.
Journal of medicinal chemistry 1992;35(6):969-81.
1992: Cline E J; Scheffel U; Boja J W; Carroll F I; Katz J L; Kuhar M J
Behavioral effects of novel cocaine analogs: a comparison with in vivo receptor binding potency.
The Journal of pharmacology and experimental therapeutics 1992;260(3):1174-9.
1992: Patel A; Boja J W; Lever J; Lew R; Simantov R; Carroll F I; Lewin A H; Philip A; Gao Y; Kuhar M J
A cocaine analog and a GBR analog label the same protein in rat striatal membranes.
Brain research 1992;576(1):173-4.
1992: Boja J W; Markham L; Patel A; Uhl G; Kuhar M J
Expression of a single dopamine transporter cDNA can confer two cocaine binding sites.
Neuroreport 1992;3(3):247-8.
1992: Shaya E K; Scheffel U; Dannals R F; Ricaurte G A; Carroll F I; Wagner H N; Kuhar M J; Wong D F
In vivo imaging of dopamine reuptake sites in the primate brain using single photon emission computed tomography (SPECT) and iodine-123 labeled RTI-55.
Synapse (New York, N.Y.) 1992;10(2):169-72.
1992: Abraham P; Pitner J B; Lewin A H; Boja J W; Kuhar M J; Carroll F I
N-modified analogues of cocaine: synthesis and inhibition of binding to the cocaine receptor.
Journal of medicinal chemistry 1992;35(1):141-4.
1992: Lewin A H; Gao Y G; Abraham P; Boja J W; Kuhar M J; Carroll F I
2 beta-substituted analogues of cocaine. Synthesis and inhibition of binding to the cocaine receptor.
Journal of medicinal chemistry 1992;35(1):135-40.
1992: Kuhar M J
Molecular pharmacology of cocaine: a dopamine hypothesis and its implications.
Ciba Foundation symposium 1992;166():81-9; discussion 89-95.
1992: Ritz M C; Kuhar M J; George F R
Molecular mechanisms associated with cocaine effects. Possible relationships with effects of ethanol.
Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism 1992;10():273-302.
1991: Vaughan R A; Simantov R; Lew R; Kuhar M J
A rapid binding assay for solubilized dopamine transporters using [3H]WIN 35,428.
Journal of neuroscience methods 1991;40(1):9-16.
1991: Shimada S; Kitayama S; Lin C L; Patel A; Nanthakumar E; Gregor P; Kuhar M; Uhl G
Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA.
Science (New York, N.Y.) 1991;254(5031):576-8.
1991: Carroll F I; Gao Y G; Rahman M A; Abraham P; Parham K; Lewin A H; Boja J W; Kuhar M J
Synthesis, ligand binding, QSAR, and CoMFA study of 3 beta-(p-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters.
Journal of medicinal chemistry 1991;34(9):2719-25.
1991: Kuhar M J; Lloyd D G; Appel N; Loats H L
Imaging receptors by autoradiography: computer-assisted approaches.
Journal of chemical neuroanatomy 1991;4(5):319-27.
1991: Battaglia G; Sharkey J; Kuhar M J; de Souza E B
Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): assessment using quantitative autoradiography.
Synapse (New York, N.Y.) 1991;8(4):249-60.
1991: Kuhar M J; Ritz M C; Boja J W
The dopamine hypothesis of the reinforcing properties of cocaine.
Trends in neurosciences 1991;14(7):299-302.
1991: Scheffel U; Pögün S; Stathis M; Boja J W; Kuhar M J
In vivo labeling of cocaine binding sites on dopamine transporters with [3H]WIN 35,428.
The Journal of pharmacology and experimental therapeutics 1991;257(3):954-8.
1991: Lew R; Vaughan R; Simantov R; Wilson A; Kuhar M J
Dopamine transporters in the nucleus accumbens and the striatum have different apparent molecular weights.
Synapse (New York, N.Y.) 1991;8(2):152-3.
1991: Pögün S; Scheffel U; Kuhar M J
Cocaine displaces [3H]WIN 35,428 binding to dopamine uptake sites in vivo more rapidly than mazindol or GBR 12909.
European journal of pharmacology 1991;198(2-3):203-5.
1991: Carroll F I; Lewin A H; Abraham P; Parham K; Boja J W; Kuhar M J
Synthesis and ligand binding of cocaine isomers at the cocaine receptor.
Journal of medicinal chemistry 1991;34(3):883-6.
1991: Boja J W; Rahman M A; Philip A; Lewin A H; Carroll F I; Kuhar M J
Isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter.
Molecular pharmacology 1991;39(3):339-45.
1991: Boja J W; Patel A; Carroll F I; Rahman M A; Philip A; Lewin A H; Kopajtic T A; Kuhar M J
[125I]RTI-55: a potent ligand for dopamine transporters.
European journal of pharmacology 1991;194(1):133-4.
1991: Lew R; Grigoriadis D; Wilson A; Boja J W; Simantov R; Kuhar M J
Dopamine transporter: deglycosylation with exo- and endoglycosidases.
Brain research 1991;539(2):239-46.
1990: Kuhar M J
A GABA transporter cDNA has been cloned.
Trends in neurosciences 1990;13(12):473-4.
1990: Ritz M C; Boja J W; Grigoriadis D; Zaczek R; Carroll F I; Lewis A H; Kuhar M J
[3H]WIN 35,065-2: a ligand for cocaine receptors in striatum.
Journal of neurochemistry 1990;55(5):1556-62.
1990: Boja J W; Carroll F I; Rahman M A; Philip A; Lewin A H; Kuhar M J
New, potent cocaine analogs: ligand binding and transport studies in rat striatum.
European journal of pharmacology 1990;184(2-3):329-32.
1990: Kuhar M J; Boja J W; Cone E J
Phencyclidine binding to striatal cocaine receptors.
Neuropharmacology 1990;29(3):295-7.
1990: Ritz M C; Cone E J; Kuhar M J
Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study.
Life sciences 1990;46(9):635-45.
1990: Kuhar M J; Sanchez-Roa P M; Wong D F; Dannals R F; Grigoriadis D E; Lew R; Milberger M
Dopamine transporter: biochemistry, pharmacology and imaging.
European neurology 1990;30 Suppl 1():15-20.
1990: Carroll F I; Rahman M A; Philip A; Lewin A H; Boja J W; Kuhar M J
Synthesis and receptor binding of cocaine analogs.
NIDA research monograph 1990;105():147-53.
1990: Zarbin M A; Wamsley J K; Kuhar M J
Anterograde transport of opioid receptors in rat vagus nerves and dorsal roots of spinal nerves: pharmacology and sensitivity to sodium and guanine nucleotides.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1990;81(2):267-78.
1989: Boja J W; Kuhar M J
[3H]cocaine binding and inhibition of [3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens.
European journal of pharmacology 1989;173(2-3):215-7.
1989: Goldsmith L T; Skurnick J H; Wojtczuk A S; Linden M; Kuhar M J; Weiss G
The antagonistic effect of oxytocin and relaxin on rat uterine segment contractility.
American journal of obstetrics and gynecology 1989;161(6 Pt 1):1644-9.
1989: Schmidt C L; de Ziegler D; Gagliardi C L; Mellon R W; Taney F H; Kuhar M J; Colon J M; Weiss G
Transfer of cryopreserved-thawed embryos: the natural cycle versus controlled preparation of the endometrium with gonadotropin-releasing hormone agonist and exogenous estradiol and progesterone (GEEP).
Fertility and sterility 1989;52(4):609-16.
1989: Grigoriadis D E; Wilson A A; Lew R; Sharkey J S; Kuhar M J
Dopamine transport sites selectively labeled by a novel photoaffinity probe: 125I-DEEP.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(8):2664-70.
1989: Titeler M; Lyon R A; Kuhar M J; Frost J F; Dannals R F; Leonhardt S; Bullock A; Rydelek L T; Price D L; Struble R G
Mu opiate receptors are selectively labelled by [3H]carfentanil in human and rat brain.
European journal of pharmacology 1989;167(2):221-8.
1989: Ritz M C; Kuhar M J
Relationship between self-administration of amphetamine and monoamine receptors in brain: comparison with cocaine.
The Journal of pharmacology and experimental therapeutics 1989;248(3):1010-7.
1989: Lew R; Grigoriadis D E; Sharkey J; Kuhar M J
Dopamine transporter: solubilization from dog caudate nucleus.
Synapse (New York, N.Y.) 1989;3(4):372-5.
1989: Scheffel U; Boja J W; Kuhar M J
Cocaine receptors: in vivo labeling with 3H-(-)cocaine, 3H-WIN 35,065-2, and 3H-WIN 35,428.
Synapse (New York, N.Y.) 1989;4(4):390-2.
1989: Witkin J M; Goldberg S R; Katz J L; Kuhar M J
Modulation of the lethal effects of cocaine by cholinomimetics.
Life sciences 1989;45(24):2295-301.
1989: Porrino L J; Ritz M C; Goodman N L; Sharpe L G; Kuhar M J; Goldberg S R
Differential effects of the pharmacological manipulation of serotonin systems on cocaine and amphetamine self-administration in rats.
Life sciences 1989;45(17):1529-35.
1989: Ritz M C; Boja J W; George F R; Kuhar M J
Cocaine binding sites related to drug self-administration.
NIDA research monograph 1989;95():239-46.
1989: Sánchez-Roa P M; Grigoriadis D E; Wilson A A; Sharkey J; Dannals R F; Villemagne V L; Wong D F; Wagner H N; Kuhar M J
[125]I-spectramide: a novel benzamide displaying potent and selective effects at the D2 dopamine receptor.
Life sciences 1989;45(19):1821-9.
1988: Sharkey J; Ritz M C; Schenden J A; Hanson R C; Kuhar M J
Cocaine inhibits muscarinic cholinergic receptors in heart and brain.
The Journal of pharmacology and experimental therapeutics 1988;246(3):1048-52.
1988: O'Hearn E; Battaglia G; De Souza E B; Kuhar M J; Molliver M E
Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(8):2788-803.
1988: Sharkey J; Glen K A; Wolfe S; Kuhar M J
Cocaine binding at sigma receptors.
European journal of pharmacology 1988;149(1-2):171-4.
1988: Goeders N E; Ritz M C; Kuhar M J
Buspirone enhances benzodiazepine receptor binding in vivo.
Neuropharmacology 1988;27(3):275-80.
1988: De Souza E B; Schmidt W K; Kuhar M J
Nalbuphine: an autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic.
The Journal of pharmacology and experimental therapeutics 1988;244(1):391-402.
1988: Ritz M C; Lamb R J; Goldberg S R; Kuhar M J
Cocaine self-administration appears to be mediated by dopamine uptake inhibition.
Progress in neuro-psychopharmacology & biological psychiatry 1988;12(2-3):233-9.
1988: Wagner H N; Weinberger D R; Kleinman J E; Casanova M F; Gibbs C J; Gur R E; Hornykiewicz O; Kuhar M J; Pettegrew J W; Seeman P
Neuroimaging and neuropathology.
Schizophrenia bulletin 1988;14(3):383-97.
1988: Kuhar M J; Ritz M C; Sharkey J
Cocaine receptors on dopamine transporters mediate cocaine-reinforced behavior.
NIDA research monograph 1988;88():14-22.
1988: Wong D F; Kuhar M J
In vivo PET and SPECT receptor imaging: new technology and tactics for receptor measurement.
Advances in experimental medicine and biology 1988;236():181-93.
1987: Ritz M C; Lamb R J; Goldberg S R; Kuhar M J
Cocaine receptors on dopamine transporters are related to self-administration of cocaine.
Science (New York, N.Y.) 1987;237(4819):1219-23.
1987: Battaglia G; Yeh S Y; O'Hearn E; Molliver M E; Kuhar M J; De Souza E B
3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.
The Journal of pharmacology and experimental therapeutics 1987;242(3):911-6.
1987: Kuhar M J
Imaging receptors for drugs in neural tissue.
Neuropharmacology 1987;26(7B):911-6.
1987: Whitehouse P J; Vale W W; Zweig R M; Singer H S; Mayeux R; Kuhar M J; Price D L; De Souza E B
Reductions in corticotropin releasing factor-like immunoreactivity in cerebral cortex in Alzheimer's disease, Parkinson's disease, and progressive supranuclear palsy.
Neurology 1987;37(6):905-9.
1987: Jampel H D; Lynch M G; Brown R H; Kuhar M J; De Souza E B
Beta-adrenergic receptors in human trabecular meshwork. Identification and autoradiographic localization.
Investigative ophthalmology & visual science 1987;28(5):772-9.
1987: Frost J J; Smith A C; Kuhar M J; Dannals R F; Wagner H N
In vivo binding of 3H-N-methylspiperone to dopamine and serotonin receptors.
Life sciences 1987;40(10):987-95.
1987: Goeders N E; Kuhar M J
Chronic cocaine administration induces opposite changes in dopamine receptors in the striatum and nucleus accumbens.
Alcohol and drug research 1987;7(4):207-16.
1986: Wong D F; Wagner H N; Tune L E; Dannals R F; Pearlson G D; Links J M; Tamminga C A; Broussolle E P; Ravert H T; Wilson A A; Toung J K; Malat J; Williams J A; O'Tuama L A; Snyder S H; Kuhar M J; Gjedde A
Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics.
Science (New York, N.Y.) 1986;234(4783):1558-63.
1986: Goeders N E; De Souza E B; Kuhar M J
Benzodiazepine receptor GABA ratios: regional differences in rat brain and modulation by adrenalectomy.
European journal of pharmacology 1986;129(3):363-6.
1986: Lyon R A; Titeler M; Frost J J; Whitehouse P J; Wong D F; Wagner H N; Dannals R F; Links J M; Kuhar M J
3H-3-N-methylspiperone labels D2 dopamine receptors in basal ganglia and S2 serotonin receptors in cerebral cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1986;6(10):2941-9.
1986: De Souza E B; Goeders N E; Kuhar M J
Benzodiazepine receptors in rat brain are altered by adrenalectomy.
Brain research 1986;381(1):176-81.
1986: Zarbin M A; Wamsley J K; Palacios J M; Kuhar M J
Autoradiographic localization of high affinity GABA, benzodiazepine, dopaminergic, adrenergic and muscarinic cholinergic receptors in the rat, monkey and human retina.
Brain research 1986;374(1):75-92.
1986: Wong D F; Gjedde A; Wagner H N; Dannals R F; Douglass K H; Links J M; Kuhar M J
Quantification of Neuroreceptors in the living human brain. II. Inhibition studies of receptor density and affinity.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1986;6(2):147-53.
1986: De Souza E B; Whitehouse P J; Kuhar M J; Price D L; Vale W W
Reciprocal changes in corticotropin-releasing factor (CRF)-like immunoreactivity and CRF receptors in cerebral cortex of Alzheimer's disease.
Nature 1986;319(6054):593-5.
1986: De Souza E B; Kuhar M J
Corticotropin-releasing factor receptors: autoradiographic identification.
Research publications - Association for Research in Nervous and Mental Disease 1986;64():179-98.
1986: De Souza E B; Kuhar M J
Corticotropin-releasing factor receptors in the pituitary gland and central nervous system: methods and overview.
Methods in enzymology 1986;124():560-90.
1986: Kuhar M J; De Souza E B; Unnerstall J R
Neurotransmitter receptor mapping by autoradiography and other methods.
Annual review of neuroscience 1986;9():27-59.
1985: De Souza E B; Insel T R; Perrin M H; Rivier J; Vale W W; Kuhar M J
Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1985;5(12):3189-203.
1985: Millington W R; Aizenman E; Bierkamper G G; Zarbin M A; Kuhar M J
Axonal transport of alpha-bungarotoxin binding sites in rat sciatic nerve.
Brain research 1985;340(2):269-76.
1985: Whitehouse P J; Trifiletti R R; Jones B E; Folstein S; Price D L; Snyder S H; Kuhar M J
Neurotransmitter receptor alterations in Huntington's disease: autoradiographic and homogenate studies with special reference to benzodiazepine receptor complexes.
Annals of neurology 1985;18(2):202-10.
1985: Goeders N E; Horst W D; O'Brien R; Bautz G; Kuhar M J
Benzodiazepine receptor binding with a new ligand, Ro 22-8515.
European journal of pharmacology 1985;113(1):147-8.
1985: Goeders N E; Kuhar M J
Benzodiazepine receptor binding in vivo with [3H]-Ro 15-1788.
Life sciences 1985;37(4):345-55.
1985: Titeler M; De Souza E B; Kuhar M J
[3H]Nitrendipine binding to calcium channels in bovine and rat pituitary.
Journal of neurochemistry 1985;44(6):1955-8.
1985: De Souza E B; Insel T R; Perrin M H; Rivier J; Vale W W; Kuhar M J
Differential regulation of corticotropin-releasing factor receptors in anterior and intermediate lobes of pituitary and in brain following adrenalectomy in rats.
Neuroscience letters 1985;56(2):121-8.
1985: De Souza E B; Seifert H; Kuhar M J
Vasoactive intestinal peptide receptor localization in rat forebrain by autoradiography.
Neuroscience letters 1985;56(2):113-20.
1985: De Souza E B; Perrin M H; Whitehouse P J; Rivier J; Vale W; Kuhar M J
Corticotropin-releasing factor receptors in human pituitary gland: autoradiographic localization.
Neuroendocrinology 1985;40(5):419-22.
1985: Whitehouse P J; Wamsley J K; Zarbin M A; Price D L; Kuhar M J
Neurotransmitter receptors in amyotrophic lateral sclerosis: possible relationship to sparing of eye movements.
Annals of neurology 1985;17(5):518.
1985: Anholt R R; De Souza E B; Kuhar M J; Snyder S H
Depletion of peripheral-type benzodiazepine receptors after hypophysectomy in rat adrenal gland and testis.
European journal of pharmacology 1985;110(1):41-6.
1985: Zarbin M A; Kuhar M J; O'Donohue T L; Wolf S S; Moody T W
Autoradiographic localization of (125I-Tyr4)bombesin-binding sites in rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1985;5(2):429-37.
1985: Wagner H N; Dannals R F; Frost J J; Wong D F; Ravert H T; Wilson A A; Links J M; Burns H D; Kuhar M J; Snyder S H
Imaging neuroreceptors in the human brain in health and disease.
Radioisotopes 1985;34(2):103-7.
1985: Summers R J; Stephenson J A; Kuhar M J
Localization of beta adrenoceptor subtypes in rat kidney by light microscopic autoradiography.
The Journal of pharmacology and experimental therapeutics 1985;232(2):561-9.
1985: De Souza E B; Anholt R R; Murphy K M; Snyder S H; Kuhar M J
Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis.
Endocrinology 1985;116(2):567-73.
1985: Inoue Y; Wagner H N; Wong D F; Links J M; Frost J J; Dannals R F; Rosenbaum A E; Takeda K; Di Chiro G; Kuhar M J
Atlas of dopamine receptor images (PET) of the human brain.
Journal of computer assisted tomography 1985;9(1):129-40.
1985: Wong D F; Wagner H N; Pearlson G; Dannals R F; Links J M; Ravert H T; Wilson A A; Suneja S; Bjorvvinssen E; Kuhar M J
Dopamine receptor binding of C-11-3-N-methylspiperone in the caudate in schizophrenia and bipolar disorder: a preliminary report.
Psychopharmacology bulletin 1985;21(3):595-8.
1985: Kuhar M J; Unnerstall J R; De Souza E B
Receptor mapping in neuropharmacology by autoradiography: some technical problems.
NIDA research monograph 1985;62():1-12.
1984: Burns H D; Dannals R F; Langström B; Ravert H T; Zemyan S E; Duelfer T; Wong D F; Frost J J; Kuhar M J; Wagner H N
(3-N-[11C]methyl)spiperone, a ligand binding to dopamine receptors: radiochemical synthesis and biodistribution studies in mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1984;25(11):1222-7.
1984: Peroutka S J; Kuhar M J
Autoradiographic localization of 5-HT1 receptors to human and canine basilar arteries.
Brain research 1984;310(1):193-6.
1984: Lepor H; Kuhar M J
Characterization of muscarinic cholinergic receptor binding in the vas deferens, bladder, prostate and penis of the rabbit.
The Journal of urology 1984;132(2):392-6.
1984: Whitehouse P J; Lynch D; Kuhar M J
Effects of postmortem delay and temperature on neurotransmitter receptor binding in a rat model of the human autopsy process.
Journal of neurochemistry 1984;43(2):553-9.
1984: Lepor H; Kuhar M J
Characterization and localization of the muscarinic cholinergic receptor in human prostatic tissue.
The Journal of urology 1984;132(2):397-402.
1984: Uhl G R; Whitehouse P J; Price D L; Tourtelotte W W; Kuhar M J
Parkinson's disease: depletion of substantia nigra neurotensin receptors.
Brain research 1984;308(1):186-90.
1984: De Souza E B; Kuhar M J
Dopamine receptors in the anterior lobe of the human pituitary gland: autoradiographic localization.
Brain research 1984;306(1-2):391-5.
1984: De Souza E B; Perrin M H; Insel T R; Rivier J; Vale W W; Kuhar M J
Corticotropin-releasing factor receptors in rat forebrain: autoradiographic identification.
Science (New York, N.Y.) 1984;224(4656):1449-51.
1984: Uhl G R; Kuhar M J
Chronic neuroleptic treatment enhances neurotensin receptor binding in human and rat substantia nigra.
Nature 1984;309(5966):350-2.
1984: Wamsley J K; Zarbin M A; Kuhar M J
Distribution of muscarinic cholinergic high and low affinity agonist binding sites: a light microscopic autoradiographic study.
Brain research bulletin 1984;12(3):233-43.
1984: Unnerstall J R; Kopajtic T A; Kuhar M J
Distribution of alpha 2 agonist binding sites in the rat and human central nervous system: analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents.
Brain research 1984;319(1):69-101.
1984: De Souza E B; Perrin M H; Rivier J; Vale W W; Kuhar M J
Corticotropin-releasing factor receptors in rat pituitary gland: autoradiographic localization.
Brain research 1984;296(1):202-7.
1984: Smith G T; Moran T H; Coyle J T; Kuhar M J; O'Donahue T L; McHugh P R
Anatomic localization of cholecystokinin receptors to the pyloric sphincter.
The American journal of physiology 1984;246(1 Pt 2):R127-30.
1984: Kuhar M J; Unnerstall J R
Mapping receptors for alpha 2-agonists in the central nervous system.
Journal of cardiovascular pharmacology 1984;6 Suppl 3():S536-42.
1983: Freed W J; Ko G N; Niehoff D L; Kuhar M J; Hoffer B J; Olson L; Cannon-Spoor H E; Morihisa J M; Wyatt R J
Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra.
Science (New York, N.Y.) 1983;222(4626):937-9.
1983: Lo M M; Niehoff D L; Kuhar M J; Snyder S H
Differential localization of type I and type II benzodiazepine binding sites in substantia nigra.
Nature 1983;306(5938):57-60.
1983: Niehoff D L; Kuhar M J
Benzodiazepine receptors: localization in rat amygdala.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(10):2091-7.
1983: Wagner H N; Burns H D; Dannals R F; Wong D F; Langstrom B; Duelfer T; Frost J J; Ravert H T; Links J M; Rosenbloom S B; Lukas S E; Kramer A V; Kuhar M J
Imaging dopamine receptors in the human brain by positron tomography.
Science (New York, N.Y.) 1983;221(4617):1264-6.
1983: Zarbin M A; Palacios J M; Wamsley J K; Kuhar M J
Axonal transport of beta-adrenergic receptors. Antero- and retrogradely transported receptors differ in agonist affinity and nucleotide sensitivity.
Molecular pharmacology 1983;24(2):341-8.
1983: Lo M M; Niehoff D L; Kuhar M J; Snyder S H
Autoradiographic differentiation of multiple benzodiazepine receptors by detergent solubilization and pharmacologic specificity.
Neuroscience letters 1983;39(1):37-44.
1983: Niehoff D L; Mashal R D; Kuhar M J
Benzodiazepine receptors: preferential stimulation of Type 1 receptors by pentobarbital.
European journal of pharmacology 1983;92(1-2):131-4.
1983: Summers R J; Kuhar M J
Autoradiographic localization of beta-adrenoceptors in rat kidney.
European journal of pharmacology 1983;91(2-3):305-10.
1983: Whitehouse P J; Wamsley J K; Zarbin M A; Price D L; Tourtellotte W W; Kuhar M J
Amyotrophic lateral sclerosis: alterations in neurotransmitter receptors.
Annals of neurology 1983;14(1):8-16.
1983: Goodman R R; Kuhar M J; Hester L; Snyder S H
Adenosine receptors: autoradiographic evidence for their location on axon terminals of excitatory neurons.
Science (New York, N.Y.) 1983;220(4600):967-9.
1983: Unnerstall J R; Molliver M E; Kuhar M J; Palacios J M
Ontogeny of opiate binding sites in the hippocampus, olfactory bulb and other regions of the rat forebrain by autoradiographic methods.
Brain research 1983;283(2-3):157-69.
1983: Zarbin M A; Innis R B; Wamsley J K; Snyder S H; Kuhar M J
Autoradiographic localization of cholecystokinin receptors in rodent brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1983;3(4):877-906.
1983: Wolf S S; Moody T W; O'Donohue T L; Zarbin M A; Kuhar M J
Autoradiographic visualization of rat brain binding sites for bombesin-like peptides.
European journal of pharmacology 1983;87(1):163-4.
1983: Atweh S F; Kuhar M J
Distribution and physiological significance of opioid receptors in the brain.
British medical bulletin 1983;39(1):47-52.
1982: Palacios J M; Kuhar M J; Rapoport S I; London E D
Effects of gamma-aminobutyric acid agonist and antagonist drugs on local cerebral glucose utilization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(7):853-60.
1982: Kuhar M J; Unnerstall J R
In vitro labeling receptor autoradiography: loss of label during ethanol dehydration and preparative procedures.
Brain research 1982;244(1):178-81.
1982: Zarbin M A; Wamsley J K; Kuhar M J
Axonal transport of muscarinic cholinergic receptors in rat vagus nerve: high and low affinity agonist receptors move in opposite directions and differ in nucleotide sensitivity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(7):934-41.
1982: Unnerstall J R; Niehoff D L; Kuhar M J; Palacios J M
Quantitative receptor autoradiography using [3H]ultrofilm: application to multiple benzodiazepine receptors.
Journal of neuroscience methods 1982;6(1-2):59-73.
1982: Niehoff D L; Mashal R D; Horst W D; O'Brien R A; Palacios J M; Kuhar M J
Binding of a radiolabeled triazolopyridazine to a subtype of benzodiazepine receptor in the rat cerebellum.
The Journal of pharmacology and experimental therapeutics 1982;221(3):670-5.
1982: Kuhar M J
Receptors for clonidine in brain: insights into therapeutic actions.
The Journal of clinical psychiatry 1982;43(6 Pt 2):17-9.
1982: Wamsley J K; Zarbin M A; Young W S; Kuhar M J
Distribution of opiate receptors in the monkey brain: an autoradiographic study.
Neuroscience 1982;7(3):595-613.
1982: Zarbin M A; Wamsley J K; Kuhar M J
Peptide receptors undergo axonal transport in the rat vagus nerve.
Advances in biochemical psychopharmacology 1982;33():463-70.
1981: Palacios J M; Kuhar M J
Neurotensin receptors are located on dopamine-containing neurones in rat midbrain.
Nature 1981;294(5841):587-9.
1981: Wamsley J K; Palacios J M; Kuhar M J
Autoradiographic localization of opioid receptors in the mammalian retina.
Neuroscience letters 1981;27(1):19-24.
1981: Palacios J M; Kuhar M J
Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study.
Brain research 1981;254(4):531-9.
1981: Palacios J M; Wamsley J K; Kuhar M J
High affinity GABA receptors-autoradiographic localization.
Brain research 1981;222(2):285-307.
1981: Palacios J M; Niehoff D L; Kuhar M J
Receptor autoradiography with tritium-sensitive film: potential for computerized densitometry.
Neuroscience letters 1981;25(2):101-5.
1981: Unnerstall J R; Kuhar M J; Niehoff D L; Palacios J M
Benzodiazepine receptors are coupled to a subpopulation of gamma-aminobutyric acid (GABA) receptors: evidence from a quantitative autoradiographic study.
The Journal of pharmacology and experimental therapeutics 1981;218(3):797-804.
1981: Zarbin M A; Wamsley J K; Innis R B; Kuhar M J
Cholecystokinin receptors: presence and axonal flow in the rat vagus nerve.
Life sciences 1981;29(7):697-705.
1981: Kuhar M J; Taylor N; Wamsley J K; Hulme E C; Birdsall N J
Muscarinic cholinergic receptor localization in brain by electron microscopic autoradiography.
Brain research 1981;216(1):1-9.
1981: Wamsley J K; Zarbin M A; Kuhar M J
Muscarinic cholinergic receptors flow in the sciatic nerve.
Brain research 1981;217(1):155-61.
1981: Palacios J M; Niehoff D L; Kuhar M J
[3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors.
Brain research 1981;213(2):277-89.
1981: Palacios J M; Wamsley J K; Kuhar M J
GABA benzodiazepine and histamine-H1 receptors in the guinea pig cerebellum: effects of kainic acid injections studied by autoradiographic methods.
Brain research 1981;214(1):155-62.
1981: Palacios J M; Kuhar M J; Rapoport S I; London E D
Increases and decreases in local cerebral glucose utilization in response to GABA agonists.
European journal of pharmacology 1981;71(2-3):333-6.
1981: Zarbin M A; Wamsley J K; Kuhar M J
Glycine receptor: light microscopic autoradiographic localization with [3H]strychnine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1981;1(5):532-47.
1981: Zarbin M A; Innis R B; Wamsley J K; Snyder S H; Kuhar M J
Autoradiographic localization of CCK receptors in guinea pig brain.
European journal of pharmacology 1981;71(2-3):349-50.
1981: Wamsley J K; Lewis M S; Young W S; Kuhar M J
Autoradiographic localization of muscarinic cholinergic receptors in rat brainstem.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1981;1(2):176-91.
1981: Young W S; Kuhar M J
Neurotensin receptor localization by light microscopic autoradiography in rat brain.
Brain research 1981;206(2):273-85.
1981: Young W S; Niehoff D; Kuhar M J; Beer B; Lippa A S
Multiple benzodiazepine receptor localization by light microscopic radiohistochemistry.
The Journal of pharmacology and experimental therapeutics 1981;216(2):425-30.
1981: Wamsley J K; Palacios J M; Young W S; Kuhar M J
Autoradiographic determination of neurotransmitter receptor distributions in the cerebral and cerebellar cortices.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1981;29(1A Suppl):125-35.
1981: Young W S; Kuhar M J
Anatomical mapping of clonidine (alpha-2 noradrenergic) receptors in rat brain: relationship to function.
Progress in clinical and biological research 1981;71():41-52.
1981: Palacios J M; Wamsley J K; Zarbin M A; Kuhar M J
GABA and glycine receptors in rat brain: autoradiographic localization.
Advances in biochemical psychopharmacology 1981;29():445-51.
1981: Palacios J M; Unnerstall J R; Young W S; Kuhar M J
Radiohistochemical studies of benzodiazepine and GABA receptors and their interactions.
Advances in biochemical psychopharmacology 1981;26():53-60.
1981: Palacios J M; Wamsley J K; Kuhar M J
The distribution of histamine H1-receptors in the rat brain: an autoradiographic study.
Neuroscience 1981;6(1):15-37.
1980: Wamsley J K; Zarbin M A; Birdsall N J; Kuhar M J
Muscarinic cholinergic receptors: autoradiographic localization of high and low affinity agonist binding sites.
Brain research 1980;200(1):1-12.
1980: Young W S; Kuhar M J
alpha 2-Adrenergic receptors are associated with renal proximal tubules.
European journal of pharmacology 1980;67(4):493-5.
1980: Goodman R R; Snyder S H; Kuhar M J; Young W S
Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(10):6239-43.
1980: Young W S; Wamsley J K; Zarbin M A; Kuhar M J
Opioid receptors undergo axonal flow.
Science (New York, N.Y.) 1980;210(4465):76-8.
1980: Batzold F; DeHaven R; Kuhar M J; Birdsall N
Inhibition of high affinity choline uptake. Structure activity studies.
Biochemical pharmacology 1980;29(18):2413-6.
1980: Murrin L C; Coyle J T; Kuhar M J
Striatal opiate receptors: pre- and postsynaptic localization.
Life sciences 1980;27(13):1175-83.
1980: Palacios J M; Kuhar M J
Beta-adrenergic-receptor localization by light microscopic autoradiography.
Science (New York, N.Y.) 1980;208(4450):1378-80.
1980: Wamsley J K; Young W S; Kuhar M J
Immunohistochemical localization of enkephalin in rat forebrain.
Brain research 1980;190(1):153-74.
1980: Young W S; Kuhar M J
Serotonin receptor localization in rat brain by light microscopic autoradiography.
European journal of pharmacology 1980;62(2-3):237-9.
1980: Young W S; Kuhar M J
Noradrenergic alpha 1 and alpha 2 receptors: light microscopic autoradiographic localization.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(3):1696-700.
1980: Kuhar M J; Birdsall N J; Burgen A S; Hulme E C
Ontogeny of muscarinic receptors in rat brain.
Brain research 1980;184(2):375-83.
1980: Young W S; Kuhar M J
Radiohistochemical localization of benzodiazepine receptors in rat brain.
The Journal of pharmacology and experimental therapeutics 1980;212(2):337-46.
1980: Palacios J M; Young W S; Kuhar M J
Autoradiographic localization of gamma-aminobutyric acid (GABA) receptors in the rat cerebellum.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(1):670-4.
1980: Wamsley J K; Young W S; Kuhar M J
Anatomical localization of enkephalin immunoreactive sites in rat forebrain.
Advances in biochemical psychopharmacology 1980;22():257-70.
1980: Kuhar M J
The benzodiazepine receptor: anatomical aspects.
NIDA research monograph 1980;(33):12-21.
1980: Young W S; Palacios J M; Kuhar M J
Histochemistry of receptors.
Advances in biochemical psychopharmacology 1980;21():51-6.
1979: Young W S; Kuhar M J
A new method for receptor autoradiography: [3H]opioid receptors in rat brain.
Brain research 1979;179(2):255-70.
1979: Murrin L C; Gale K; Kuhar M J
Autoradiographic localization of neuroleptic and dopamine receptors in the caudate-putamen and substantia nigra: effects of lesions.
European journal of pharmacology 1979;60(2-3):229-35.
1979: Palacios J M; Niehoff D L; Kuhar M J
Ontogeny of GABA and benzodiazepine receptors: effects of Triton X-100, bromide and muscimol.
Brain research 1979;179(2):390-5.
1979: Palacios J M; Kuhar M J
Choline: binding studies provide some evidence for a weak, direct agonist action in brain.
Molecular pharmacology 1979;16(3):1084-8.
1979: Murrin L C; Kuhar M J
Dompamine receptors in the rat frontal cortex: an autoradiographic study.
Brain research 1979;177(2):279-85.
1979: Young W S; Kuhar M J
Noradrenergic alpha 1 and alpha 2 receptors: autoradiographic visualization.
European journal of pharmacology 1979;59(3-4):317-9.
1979: Palacios J M; Young W S; Kuhar M J
Autoradiographic localization of H1-histamine receptors in brain using 3H-mepyramine: preliminary studies.
European journal of pharmacology 1979;58(3):295-304.
1979: Young W S; Kuhar M J
Neurotensin receptors: autoradiographic localization in rat CNS.
European journal of pharmacology 1979;59(1-2):161-3.
1979: Niehoff D L; Palacios J M; Kuhar M J
In vivo receptor binding: attempts to improve specific/non-specific ratios.
Life sciences 1979;25(10):819-26.
1979: Young W S; Kuhar M J
Autoradiographic localisation of benzodiazepine receptors in the brains of humans and animals.
Nature 1979;280(5721):391-4.
1979: Klemm N; Murrin L C; Kuhar M J
Neuroleptic and dopamine receptors: autoradiographic localization of [3H]spiperone in rat brain.
Brain research 1979;169(1):1-9.
1979: Klemm N; Kuhar M J
Post-mortem changes in high affinity choline uptake.
Journal of neurochemistry 1979;32(5):1487-94.
1979: Uhl G R; Goodman R R; Kuhar M J; Childers S R; Snyder S H
Immunohistochemical mapping of enkephalin containing cell bodies, fibers and nerve terminals in the brain stem of the rat.
Brain research 1979;166(1):75-94.
1979: Kuhar M J; Mak L L; Lietman P S
Autoradiographic localization of [3H]gentamicin in the proximal renal tubules of mice.
Antimicrobial agents and chemotherapy 1979;15(1):131-3.
1979: Kuhar M J
Sodium-dependent high affinity choline uptake.
Progress in brain research 1979;49():71-6.
1979: Kuhar M J; Uhl G R
Histochemical localization of opiate receptors and the enkephalins.
Advances in biochemical psychopharmacology 1979;20():53-68.
1978: Young W S; Uhl G R; Kuhar M J
Iontophoresis of neurotensin in the area of the locus coeruleus.
Brain research 1978;150(2):431-5.
1978: Coyle J T; Molliver M E; Kuhar M J
In situ injection of kainic acid: a new method for selectively lesioning neural cell bodies while sparing axons of passage.
The Journal of comparative neurology 1978;180(2):301-23.
1978: Kuhar M J; Zarbin M A
Synaptosomal transport: a chloride dependence for choline, GABA, glycine and several other compounds.
Journal of neurochemistry 1978;31(1):251-6.
1978: Murrin L C; Lewis M S; Kuhar M J
Amino acid transport: alterations due to synaptosomal depolarization.
Life sciences 1978;22(22):2009-16.
1978: Uhl G R; Kuhar M J; Synder S H
Enkephalin-containing pathway: amygdaloid efferents in the stria terminalis.
Brain research 1978;149(1):223-8.
1978: Kuhar M J
Histochemical localization of opiate receptors and opioid peptides.
Federation proceedings 1978;37(2):153-7.
1978: Kuhar M J; Murrin L C; Malouf A T; Klemm N
Dopamine receptor binding in vivo: the feasibility of autoradiographic studies.
Life sciences 1978;22(2):203-10.
1978: Kuhar M J; Murrin L C
Sodium-dependent, high affinity choline uptake.
Journal of neurochemistry 1978;30(1):15-21.
1978: Atweh S F; Murrin L C; Kuhar M J
Presynaptic localization of opiate receptors in the vagal and accessory optic systems: an autoradiographic study.
Neuropharmacology 1978;17(1):65-71.
1978: Uhl G R; Goodman R R; Kuhar M J; Snyder S H
Enkephalin and neurotensin: immunohistochemical localization and identification of an amygdalofugal pathway.
Advances in biochemical psychopharmacology 1978;18():71-87.
1978: Kuhar M J
Opiate receptors: some anatomical and physiological aspects.
Annals of the New York Academy of Sciences 1978;311():35-48.
1977: Murrin L C; Enna S J; Kuhar M J
Autoradiographic localization of [3H]reserpine binding sites in rat brain.
The Journal of pharmacology and experimental therapeutics 1977;203(3):564-74.
1977: Murrin L C; DeHaven R N; Kuhar M J
On the relationship between (3H)choline uptake activation and (3H)acetylcholine release.
Journal of neurochemistry 1977;29(4):681-7.
1977: Atweh S F; Kuhar M J
Autoradiographic localization of opiate receptors in rat brain. III. The telencephalon.
Brain research 1977;134(3):393-405.
1977: Uhl G R; Kuhar M J; Snyder S H
Neurotensin: immunohistochemical localization in rat central nervous system.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(9):4059-63.
1977: Young W S; Bird S J; Kuhar M J
Iontophoresis of methionine-enkephalin in the locus coeruleus area.
Brain research 1977;129(2):366-70.
1977: Atweh S F; Kuhar M J
Autoradiographic localization of opiate receptors in rat brain. II. The brain stem.
Brain research 1977;129(1):1-12.
1977: Simantov R; Kuhar M J; Uhl G R; Snyder S H
Opioid peptide enkephalin: immunohistochemical mapping in rat central nervous system.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(5):2167-71.
1977: Atweh S F; Kuhar M J
Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla.
Brain research 1977;124(1):53-67.
1977: Bird S J; Kuhar M J
Iontophoretic application of opiates to the locus coeruleus.
Brain research 1977;122(3):523-33.
1976: Murrin L C; Kuhar M J
Activation of high-affinity choline uptake in vitro by depolarizing agents.
Molecular pharmacology 1976;12(6):1082-90.
1976: Pert C B; Kuhar M J; Snyder S H
Opiate receptor: autoradiographic localization in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(10):3729-33.
1976: Simon J R; Kuhar M J
High affinity choline uptake: ionic and energy requirements.
Journal of neurochemistry 1976;27(1):93-9.
1976: Kuhar M; Yamamura H I
Localization of cholinergic muscarinic receptors in rat brain by light microscopic radioautography.
Brain research 1976;110(2):229-43.
1976: Atweh S F; Kuhar M J
Effects of anesthetics and septal lesions and stimulation on 3H-acetylcholine formation in rat hippocampus.
European journal of pharmacology 1976;37(2):311-9.
1976: Simon J R; Atweh S; Kuhar M J
Sodium-dependent high affinity choline uptake: a regulatory step in the synthesis of acetylcholine.
Journal of neurochemistry 1976;26(5):909-22.
1976: Simantov R; Kuhar M J; Pasternak G W; Snyder S H
The regional distribution of a morphine-like factors enkephalin in monkey brain.
Brain research 1976;106(1):189-97.
1976: Simon J R; Contrera J F; Kuhar M J
Binding of [3H] kainic acid, and analogue of Lglutamate, to brain membranes.
Journal of neurochemistry 1976;26(1):141-7.
1975: Kuhar M J; Simon J R; Taylor N
Serotonergic synaptosomes from rat hippocampus: lack of acetylcholinesterase.
Brain research 1975;99(2):415-8.
1975: Atweh S; Simon J R; Kuhar M J
Utilization of sodium-dependent high affinity choline uptake in vitro as a measure of the activity of cholinergic neurons in vivo.
Life sciences 1975;17(10):1535-44.
1975: Rommelspacher H; Kuhar M J
Effects of drugs and axotomy on acetylcholine levels in central cholinergic neurons.
Naunyn-Schmiedeberg's archives of pharmacology 1975;291(1):17-21.
1975: Kuhar M J; DeHaven R N; Yamamura H I; Rommel-Spacher H; Simon J R
Further evidence for cholinergic habenulo-interpeduncular neurons: pharmacologic and functional characteristics.
Brain research 1975;97(2):265-75.
1975: Snyder S H; Chang K J; Kuhar M J; Yamamura H I
Biochemical indentification of the mammalian muscarinic cholinergic receptor.
Federation proceedings 1975;34(10):1915-21.
1975: Enna S J; Kuhar M J; Snyder S H
Regional distribution of postsynaptic receptor binding for gamma-aminobutyric acid (GABA) in monkey brain.
Brain research 1975;93(1):168-74.
1975: Pert C B; Kuhar M J; Snyder S H
Autoradiograhic localization of the opiate receptor in rat brain.
Life sciences 1975;16(12):1849-53.
1975: Simon J R; Kuhar M G
Impulse-flow regulation of high affinity choline uptake in brain cholinergic nerve terminals.
Nature 1975;255(5504):162-3.
1975: Kuhar M J; Yamamura H I
Light autoradiographic localisation of cholinergic muscarinic receptors in rat brain by specific binding of a potent antagonist.
Nature 1975;253(5492):560-1.
1975: Rommelspacher H; Kuhar M J
Effects of dopaminergic drugs and acute medial forebrain bundle lesions on striatal acetylcholine levels.
Life sciences 1975;16(1):65-70.
1975: Bunney B S; Walters J R; Kuhar M J; Roth R H; Aghajanian G K
D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons.
Psychopharmacology communications 1975;1(2):177-90.
1975: Rommelspacher H; Kuhar M J
Proceedings: Effect of drugs on alterations of neuronal impulse flow of a central cholinergic tract.
Naunyn-Schmiedeberg's archives of pharmacology 1975;287 Suppl():R10.
1974: Owellen R J; Donigian D W; Hartke C A; Dickerson R M; Kuhar M J
The binding of vinblastine to tubulin and to particulate fractions of mammalian brain.
Cancer research 1974;34(12):3180-6.
1974: Rommelspacher H; Kuhar M J
Effects of electrical stimulation on acetylcholine levels in central cholinergic nerve terminals.
Brain research 1974;81(2):243-51.
1974: Yamamura H I; Kuhar M J; Snyder S H
In vivo identification of muscarinic cholinergic receptor binding in rat brain.
Brain research 1974;80(1):170-6.
1974: Rommelspacher H; Goldberg A M; Kuhar M J
Action of hemicholinium-3 on cholinergic nerve terminals after alteration of neuronal impulse flow.
Neuropharmacology 1974;13(10-11):1015-23.
1974: Dismukes K; Kuhar M J; Snyder S H
Brain histamine alterations after hypothalamic isolation.
Brain research 1974;78(1):144-51.
1974: Kuhar M J; Rommelspacher H
Acetylcholinesterase-staining synaptosomes from rat hippocampus: relative frequency and tentative estimation of internal concentration of free or 'labile bound' acetylcholine.
Brain research 1974;77(1):85-96.
1974: Snyder S H; Brown B; Kuhar M J
The subsynaptosomal localization of histamine, histidine decarboxylase and histamine methyltransferase in rat hypothalamus.
Journal of neurochemistry 1974;23(1):37-45.
1974: Kuhar M J; Simon J R
Acetylcholine uptake: lack of association with cholinergic neurons.
Journal of neurochemistry 1974;22(6):1135-7.
1974: Mulder A H; Yamamura H I; Kuhar M J; Snyder S H
Release of acetylcholine from hippocampal slices by potassium depolarization: dependence on high affinity choline uptake.
Brain research 1974;70(2):372-6.
1974: Coyle J T; Kuhar M J
Subcellular localization of dopamine beta-hydroxylase and endogenous norepinephrine in the rat hypothalamus.
Brain research 1974;65(3):475-87.
1974: Kuhar M J; Aghajanian G K; Roth R H
Serotonin neurons: a synaptic mechanism for the reuptake of serotonin.
Advances in biochemical psychopharmacology 1974;10():287-95.
1973: Kuhar M J
Neurotransmitter uptake: a tool in identifying neurotransmitter-specific pathways.
Life sciences 1973;13(12):1623-34.
1973: Kuhar M J; Pert C B; Snyder S H
Regional distribution of opiate receptor binding in monkey and human brain.
Nature 1973;245(5426):447-50.
1973: Sethy V H; Roth R H; Kuhar M J; Van Woert M H
Choline and acetylcholine: regional distribution and effect of degeneration of cholinergic nerve terminals in the rat hippocampus.
Neuropharmacology 1973;12(9):819-23.
1973: Sethy V H; Kuhar M J; Roth R H; Van Woert M H; Aghajanian G K
Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus.
Brain research 1973;55(2):481-4.
1973: Aghajanian G K; Kuhar M J; Roth R H
Serotonin-containing neuronal perikarya and terminals: differential effects of P-chlorophenylalanine.
Brain research 1973;54():85-101.
1973: Kuhar M J; Sethy V H; Roth R H; Aghajanian G K
Choline: selective accumulation by central cholinergic neurons.
Journal of neurochemistry 1973;20(2):581-93.
1973: Kuhar M J; Aghajanian G K
Selective accumulation of 3 H-serotonin by nerve terminals of raphe neurones: an autoradiographic study.
Nature: New biology 1973;241(110):187-9.
1972: Bustos G; Kuhar M J; Roth R H
Effect of gamma-hydroxybutyrate and gamma-butyrolactone on dopamine synthesis and uptake by rat striatum.
Biochemical pharmacology 1972;21(19):2649-52.
1972: Kuhar M J; Aghajanian G K; Roth R H
Tryptophan hydroxylase activity and synaptosomal uptake of serotonin in discrete brain regions after midbrain raphe lesions: correlations with serotonin levels and histochemical fluorescence.
Brain research 1972;44(1):165-76.
1972: Kuhar M J; Roth R H; Aghajanian G K
Synthesis of catecholamines in the locus coeruleus from 3 H-tyrosine in vivo.
Biochemical pharmacology 1972;21(16):2280-2.
1972: Kuhar M J; Roth R H; Aghajanian G K
Synaptosomes from forebrains of rats with midbrain raphe lesions: selective reduction of serotonin uptake.
The Journal of pharmacology and experimental therapeutics 1972;181(1):36-45.
1971: Kuhar M J; Roth R H; Aghajanian G K
Selective reduction of tryptophan hydroxylase activity in rat forebrain after midbrain raphe lesions.
Brain research 1971;35(1):167-76.
1971: Kuhar M J; Taylor K M; Snyder S H
The subcellular localization of histamine and histamine methyltransferase in rat brain.
Journal of neurochemistry 1971;18(8):1515-27.
1971: Wofsey A R; Kuhar M J; Snyder S H
A unique synaptosomal fraction, which accumulates glutamic and aspartic acids, in brain tissue.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(6):1102-6.
1971: Kuhar M J; Shaskan E G; Snyder S H
The subcellular distribution of endogenous and exogenous serotonin in brain tissue: comparison of synaptosomes storing serotonin, norepinephrine, and gamma-aminobutyric acid.
Journal of neurochemistry 1971;18(3):333-43.
1971: Kuhar M J
A possible mechanism for the pathogenic action of monosodium glutamate.
Research communications in chemical pathology and pharmacology 1971;2(1):95-7.
1971: Gfeller E; Kuhar M J; Snyder S H
Neurotransmitter-specific synaptosomes in rat corpus striatum: morphological variations.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(1):155-9.
1970: Kuhar M J; Green A I; Snyder S H; Gfeller E
Separation of synaptosomes storing catecholamines and gamma-aminobutyric acid in rat corpus striatum.
Brain research 1970;21(3):405-17.
1970: Kuhar M J; Snyder S H
The subcellular distribution of free H3-glutamic acid in rat cerebral cortical slices.
The Journal of pharmacology and experimental therapeutics 1970;171(1):141-52.

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