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Mübeccel Akdis

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Cansin Sackesen; Ozge U Soyer; B Stanic; W van de Veen; J Zumkehr; Mübeccel Akdis; S S Alkan; I Gursel; O Kalaycı; B Ruckert; Cezmi A. Akdis
Suppression of B-cell activation and IgE, IgA, IgG1 and IgG4 production by mammalian telomeric oligonucleotides.
Willem van de Veen; Marcin Wawrzyniak; Görkem Yaman; Cezmi A. Akdis; Deniz G Akdis; Beate Rückert; Stefan Söllner; Barbara Stanic; Mübeccel Akdis
IgG4 production is confined to human IL-10-producing regulatory B cells that suppress antigen-specific immune responses.
Umut Can Kücüksezer; Andreas Nandy; Oscar Palomares; Tuomo Puhakka; Beate Rückert; Günnur Deniz; Heinz B Fahrner; Bilun Gemicioğlu; Tuomas Jartti; Andreas Jung; Cezmi A. Akdis; Mübeccel Akdis
Triggering of specific Toll-like receptors and proinflammatory cytokines breaks allergen-specific T-cell tolerance in human tonsils and peripheral blood.

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All Publications

2013: Cansin Sackesen; Ozge U Soyer; B Stanic; W van de Veen; J Zumkehr; Mübeccel Akdis; S S Alkan; I Gursel; O Kalaycı; B Ruckert; Cezmi A. Akdis
Suppression of B-cell activation and IgE, IgA, IgG1 and IgG4 production by mammalian telomeric oligonucleotides.
Allergy 2013;68(5):593-603.
2013: Willem van de Veen; Marcin Wawrzyniak; Görkem Yaman; Cezmi A. Akdis; Deniz G Akdis; Beate Rückert; Stefan Söllner; Barbara Stanic; Mübeccel Akdis
IgG4 production is confined to human IL-10-producing regulatory B cells that suppress antigen-specific immune responses.
The Journal of allergy and clinical immunology 2013;131(4):1204-12.
2013: Umut Can Kücüksezer; Andreas Nandy; Oscar Palomares; Tuomo Puhakka; Beate Rückert; Günnur Deniz; Heinz B Fahrner; Bilun Gemicioğlu; Tuomas Jartti; Andreas Jung; Cezmi A. Akdis; Mübeccel Akdis
Triggering of specific Toll-like receptors and proinflammatory cytokines breaks allergen-specific T-cell tolerance in human tonsils and peripheral blood.
The Journal of allergy and clinical immunology 2013;131(3):875-85.
2013: O U Soyer; Mübeccel Akdis; H Behrendt; Reto Crameri; Roger Lauener; Johannes Ring; Cezmi A. Akdis
Mechanisms of peripheral tolerance to allergens.
Allergy 2013;68(2):161-70.
2012: Natalija Novak; Judith Zumkehr; Mübeccel Akdis; Thomas Bieber; Caroline Bussmann; Marek Jutel; Laura Maintz; Nihal Mete; Cezmi Akdis
Early suppression of basophil activation during allergen-specific immunotherapy by histamine receptor 2.
The Journal of allergy and clinical immunology 2012;130(5):1153-1158.e2.
2012: Mübeccel Akdis; Oscar Palomares; Willem van de Veen; Marloes van Splunter; Cezmi A. Akdis
TH17 and TH22 cells: a confusion of antimicrobial response with tissue inflammation versus protection.
The Journal of allergy and clinical immunology 2012;129(6):1438-49; quiz1450-1.
2012: Gabriela Senti; Ozge Soyer; Martin Steiner; Christine Tivig; Marianne van Hage; Anna Zaleska; Daniela Kuster; Julia M Martinez-Gomez; Horst Rose; Cezmi A. Akdis; Mübeccel Akdis; Reto Crameri; Nicole Graf; Hans Grönlund; Ludwig A Hothorn; Pål Johansen; Thomas M Kündig
Intralymphatic immunotherapy for cat allergy induces tolerance after only 3 injections.
The Journal of allergy and clinical immunology 2012;129(5):1290-6.
2012: Ana Rebane; Jaak Vilo; Stephan Weidinger; Maya Zimmermann; Alar Aab; Kristi Abram; Mübeccel Akdis; Hansjörg Baurecht; Regina Fölster-Holst; Andre Franke; Thomas Illig; Mati Karelson; Lajos Kemeny; Külli Kingo; Andrea Koreck; Tauno Metsalu; Norbert Meyer; Nikoletta Nagy; Natalija Novak; Maire Pihlap; Cezmi A. Akdis
Mechanisms of IFN-γ-induced apoptosis of human skin keratinocytes in patients with atopic dermatitis.
The Journal of allergy and clinical immunology 2012;129(5):1297-306.
2012: Mübeccel Akdis; Cezmi A. Akdis
IgE class switching and cellular memory.
Nature immunology 2012;13(4):312-4.
2012: Norbert Meyer; Claudio Rhyner; Michael Soyka; Kerstin Wanke; Paulina Wawrzyniak; Sherrie Zhang; Mübeccel Akdis; Simone Bürgler; Maciej Chalubinski; Janine Christoph; Thomas Eiwegger; Hiroyuki Fujita; Philippe Indermitte; Heidi Makrinioti; Günter Menz; Cezmi A. Akdis
Inhibition of angiogenesis by IL-32: possible role in asthma.
The Journal of allergy and clinical immunology 2012;129(4):964-73.e7.
2012: Oscar Palomares; Tuomo Puhakka; Beate Rückert; Andreas Speiser; Mübeccel Akdis; Heinz B Fahrner; Enrique Gomez; Tuomas Jartti; Andreas Jung; Livije Kalogjera; Umut Can Kücüksezer; William W Kwok; Cezmi A. Akdis
Induction and maintenance of allergen-specific FOXP3+ Treg cells in human tonsils as potential first-line organs of oral tolerance.
The Journal of allergy and clinical immunology 2012;129(2):510-20, 520.e1-9.
2012: Hiroyuki Fujita; Norbert Meyer; Mübeccel Akdis; Cezmi A. Akdis
Mechanisms of immune tolerance to allergens.
Chemical immunology and allergy 2012;96():30-8.
2012: Hiroyuki Fujita; Michael B Soyka; Mübeccel Akdis; Cezmi A. Akdis
Mechanisms of allergen-specific immunotherapy.
Clinical and translational allergy 2012;2(1):2.
2011: B A Sin; J Zumkehr; Mübeccel Akdis; C Bekpen; S Bezzine; G Lambeau; Cezmi A. Akdis
T-cell and antibody responses to phospholipase A2 from different species show distinct cross-reactivity patterns.
Allergy 2011;66(12):1513-21.
2011: Liam O'Mahony; Mübeccel Akdis; Cezmi A. Akdis
Regulation of the immune response and inflammation by histamine and histamine receptors.
The Journal of allergy and clinical immunology 2011;128(6):1153-62.
2011: Cevdet Ozdemir; Mübeccel Akdis; Umut Can Kucuksezer; Cezmi A. Akdis
Specific immunotherapy and turning off the T cell: how does it work?
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2011;107(5):381-92.
2011: C Ozdemir; Mübeccel Akdis; U C Kucuksezer; Cezmi A. Akdis
Mechanisms of immunotherapy to wasp and bee venom.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011;41(9):1226-34.
2011: Günnur Deniz; Mübeccel Akdis
NK cell subsets and their role in allergy.
Expert opinion on biological therapy 2011;11(7):833-41.
2011: Hiroyuki Fujita; Maciej Chalubinski; Claudio Rhyner; Philippe Indermitte; Norbert Meyer; Ruth Ferstl; Angela Treis; Enrique Gomez; Ahmet Akkaya; Liam O'Mahony; Mübeccel Akdis; Cezmi A. Akdis
Claudin-1 expression in airway smooth muscle exacerbates airway remodeling in asthmatic subjects.
The Journal of allergy and clinical immunology 2011;127(6):1612-21.e8.
2011: Béatrice Vanbervliet; Mübeccel Akdis; Marc Vocanson; Aurore Rozières; Josette Benetière; Paul Rouzaire; Cezmi A. Akdis; Jean-François Nicolas; Anca Hennino
Histamine receptor H1 signaling on dendritic cells plays a key role in the IFN-γ/IL-17 balance in T cell-mediated skin inflammation.
The Journal of allergy and clinical immunology 2011;127(4):943-53.e1-10.
2011: Mübeccel Akdis; Simone Burgler; Reto Crameri; Thomas Eiwegger; Hiroyuki Fujita; Enrique Gomez; Sven Klunker; Norbert Meyer; Liam O'Mahony; Oscar Palomares; Claudio Rhyner; Nadia Quaked; Anna Schaffartzik; Willem Van De Veen; Sabine Zeller; Maya Zimmermann; Nadia Ouaked; Cezmi A. Akdis
Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases.
The Journal of allergy and clinical immunology 2011;127(3):701-21.e1-70.
2011: Tunc Akkoc; Mübeccel Akdis; Cezmi A. Akdis
Update in the mechanisms of allergen-specific immunotheraphy.
Allergy, asthma & immunology research 2011;3(1):11-20.
2011: Cezmi A. Akdis; Mübeccel Akdis
Mechanisms of allergen-specific immunotherapy.
The Journal of allergy and clinical immunology 2011;127(1):18-27; quiz 28-9.
2011: C Sackesen; E Birben; O U Soyer; U M Sahiner; T S Yavuz; E Civelek; E Karabulut; Mübeccel Akdis; Cezmi A. Akdis; O Kalayci
The effect of CD14 C159T polymorphism on in vitro IgE synthesis and cytokine production by PBMC from children with asthma.
Allergy 2011;66(1):48-57.
2010: Mübeccel Akdis
The cellular orchestra in skin allergy; are differences to lung and nose relevant?
Current opinion in allergy and clinical immunology 2010;10(5):443-51.
2010: Oscar Palomares; Görkem Yaman; Ahmet K Azkur; Tunc Akkoc; Mübeccel Akdis; Cezmi A. Akdis
Role of Treg in immune regulation of allergic diseases.
European journal of immunology 2010;40(5):1232-40.
2010: Norbert Meyer; Maya Zimmermann; Simone Bürgler; Claudio Bassin; Stefan Woehrl; Katharina Moritz; Claudio Rhyner; Philippe Indermitte; Peter Schmid-Grendelmeier; Mübeccel Akdis; Günter Menz; Cezmi A. Akdis
IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic dermatitis.
The Journal of allergy and clinical immunology 2010;125(4):858-865.e10.
2010: Cevdet Ozdemir; Mübeccel Akdis; Cezmi A. Akdis
T-cell response to allergens.
Chemical immunology and allergy 2010;95():22-44.
2009: Marek Jutel; Mübeccel Akdis; Cezmi A. Akdis
Histamine, histamine receptors and their role in immune pathology.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(12):1786-800.
2009: Mübeccel Akdis
Immune tolerance in allergy.
Current opinion in immunology 2009;21(6):700-7.
2009: Sven Klunker; Mark M W Chong; Pierre-Yves Mantel; Oscar Palomares; Claudio Bassin; Mario Ziegler; Beate Rückert; Flurina Meiler; Mübeccel Akdis; Dan R Littman; Cezmi A. Akdis
Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells.
The Journal of experimental medicine 2009;206(12):2701-15.
2009: Mübeccel Akdis; Cezmi A. Akdis
Therapeutic manipulation of immune tolerance in allergic disease.
Nature reviews. Drug discovery 2009;8(8):645-60.
2009: K Solarewicz-Madejek; T M Basinski; Reto Crameri; Mübeccel Akdis; A Akkaya; Kurt Blaser; K F Rabe; Cezmi A. Akdis; Marek Jutel
T cells and eosinophils in bronchial smooth muscle cell death in asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(6):845-55.
2009: Cevdet Ozdemir; Mübeccel Akdis; Cezmi A. Akdis
T regulatory cells and their counterparts: masters of immune regulation.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(5):626-39.
2009: Cezmi A. Akdis; Mübeccel Akdis
Mechanisms and treatment of allergic disease in the big picture of regulatory T cells.
The Journal of allergy and clinical immunology 2009;123(4):735-46; quiz 747-8.
2009: Alison Taylor; Johan Verhagen; Tunç Akkoç; Renate Wenig; Egbert Flory; Kurt Blaser; Mübeccel Akdis; Cezmi A. Akdis
IL-10 suppresses CD2-mediated T cell activation via SHP-1.
Molecular immunology 2009;46(4):622-9.
2008: Flurina Meiler; Judith Zumkehr; Sven Klunker; Beate Rückert; Cezmi A. Akdis; Mübeccel Akdis
In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure.
The Journal of experimental medicine 2008;205(12):2887-98.
2008: F Meiler; Sven Klunker; M Zimmermann; Cezmi A. Akdis; Mübeccel Akdis
Distinct regulation of IgE, IgG4 and IgA by T regulatory cells and toll-like receptors.
Allergy 2008;63(11):1455-63.
2008: Ulrich R Müller; Marek Jutel; Andrea Reimers; Judith Zumkehr; Clarissa Huber; Carola Kriegel; Urs Steiner; Gabrielle Haeberli; Mübeccel Akdis; Arthur Helbling; Benno Schnyder; Kurt Blaser; Cezmi A. Akdis
Clinical and immunologic effects of H1 antihistamine preventive medication during honeybee venom immunotherapy.
The Journal of allergy and clinical immunology 2008;122(5):1001-1007.e4.
2008: Cevdet Ozdemir; Mübeccel Akdis; Cezmi A. Akdis
Nature of regulatory T cells in the context of allergic disease.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2008;4(3):106-10.
2008: Mübeccel Akdis
T-cell tolerance to inhaled allergens: mechanisms and therapeutic approaches.
Expert opinion on biological therapy 2008;8(6):769-77.
2008: Tunc Akkoc; Pieter J A de Koning; Beate Rückert; Isil Barlan; Mübeccel Akdis; Cezmi A. Akdis
Increased activation-induced cell death of high IFN-gamma-producing T(H)1 cells as a mechanism of T(H)2 predominance in atopic diseases.
The Journal of allergy and clinical immunology 2008;121(3):652-658.e1.
2008: Günnur Deniz; Gaye Erten; Umut Can Kücüksezer; Dilara Kocacik; Christian Karagiannidis; Esin Aktas; Cezmi A. Akdis; Mübeccel Akdis
Regulatory NK cells suppress antigen-specific T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):850-7.
2008: Mübeccel Akdis
Immunologic responses to sublingual allergen immunotherapy.
Clinical allergy and immunology 2008;21():71-86.
2008: Cezmi A. Akdis; Marek Jutel; Mübeccel Akdis
Regulatory effects of histamine and histamine receptor expression in human allergic immune responses.
Chemical immunology and allergy 2008;94():67-82.
2007: Carsten B Schmidt-Weber; Mübeccel Akdis; Cezmi A. Akdis
TH17 cells in the big picture of immunology.
The Journal of allergy and clinical immunology 2007;120(2):247-54.
2007: Sarah Thunberg; Mübeccel Akdis; Cezmi A. Akdis; Reidar Grönneberg; Vivianne Malmström; Christina Trollmo; Marianne van Hage; Guro Gafvelin
Immune regulation by CD4+CD25+ T cells and interleukin-10 in birch pollen-allergic patients and non-allergic controls.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(8):1127-36.
2007: Alison Taylor; Mübeccel Akdis; Andrea Joss; Tunç Akkoç; Renate Wenig; Marco COLONna; Isabelle Daigle; Egbert Flory; Kurt Blaser; Cezmi A. Akdis
IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain-containing protein tyrosine phosphatase 1.
The Journal of allergy and clinical immunology 2007;120(1):76-83.
2007: Metin Aydogan; Nihal Mete; Didem Yazi; Tunc Akkoc; Cevdet Ozdemir; Kurt Blaser; Mübeccel Akdis; Cezmi A. Akdis; Nerin N Bahceciler; Isil B Barlan
Comparison of Der p1-specific antibody levels in children with allergic airway disease and healthy controls.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2007;18(4):320-5.
2007: Mübeccel Akdis; Cezmi A. Akdis
Mechanisms of allergen-specific immunotherapy.
The Journal of allergy and clinical immunology 2007;119(4):780-91.
2007: T Basinski; C Ozdemir; C Sackesen; Pierre-Yves Mantel; Isil B Barlan; Mübeccel Akdis; Marek Jutel; Cezmi A. Akdis
Highlights in cellular and molecular mechanisms of allergic diseases. XXVth Congress of the European Academy of Allergology and Clinical Immunology in Vienna.
International archives of allergy and immunology 2007;142(2):91-8.
2006: Mübeccel Akdis
Healthy immune response to allergens: T regulatory cells and more.
Current opinion in immunology 2006;18(6):738-44.
2006: Cezmi A. Akdis; Mübeccel Akdis; Thomas Bieber; Carsten Bindslev-Jensen; M Boguniewicz; Philippe Eigenmann; Q Hamid; A Kapp; D Y M Leung; Jasna Lipozencic; T A Luger; Antonella Muraro; N Novak; Thomas A E Platts-Mills; L Rosenwasser; Annika Scheynius; Estelle Simons; Jonathan M Spergel; K Turjanmaa; Ulrich Wahn; S Weidinger; Thomas Werfel; Torsten Zuberbier
Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report.
Allergy 2006;61(8):969-87.
2006: Cezmi A. Akdis; Mübeccel Akdis; Thomas Bieber; Carsten Bindslev-Jensen; Mark Boguniewicz; Philippe Eigenmann; Qutayba Hamid; Alexander Kapp; Donald Y M Leung; Jasna Lipozencic; Thomas A Luger; Antonella Muraro; Natalija Novak; Thomas A E Platts-Mills; Lanny Rosenwasser; Annika Scheynius; Estelle Simons; Jonathan M Spergel; Kristiina Turjanmaa; Ulrich Wahn; Stefan Weidinger; Thomas Werfel; Torsten Zuberbier
Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report.
The Journal of allergy and clinical immunology 2006;118(1):152-69.
2006: Marek Jutel; Mübeccel Akdis; Kurt Blaser; Cezmi A. Akdis
Mechanisms of allergen specific immunotherapy--T-cell tolerance and more.
Allergy 2006;61(7):796-807.
2006: Isil B Barlan; Nerin N Bahceciler; Mübeccel Akdis; Cezmi A. Akdis
Bacillus Calmette-Guerin, Mycobacterium bovis, as an immunomodulator in atopic diseases.
Immunology and allergy clinics of North America 2006;26(2):365-77, ix.
2006: Johan Verhagen; Kurt Blaser; Cezmi A. Akdis; Mübeccel Akdis
Mechanisms of allergen-specific immunotherapy: T-regulatory cells and more.
Immunology and allergy clinics of North America 2006;26(2):207-31, vi.
2006: Alison Taylor; Johan Verhagen; Kurt Blaser; Mübeccel Akdis; Cezmi A. Akdis
Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells.
Immunology 2006;117(4):433-42.
2006: Flurina Meiler; Maya Zimmermann; Kurt Blaser; Cezmi A. Akdis; Mübeccel Akdis
T-cell subsets in the pathogenesis of human asthma.
Current allergy and asthma reports 2006;6(2):91-6.
2006: Haluk B Oral; Sergei V Kotenko; Mustafa Yilmaz; Orlando Mani; Judith Zumkehr; Kurt Blaser; Cezmi A. Akdis; Mübeccel Akdis
Regulation of T cells and cytokines by the interleukin-10 (IL-10)-family cytokines IL-19, IL-20, IL-22, IL-24 and IL-26.
European journal of immunology 2006;36(2):380-8.
2006: Cezmi A. Akdis; Isil B Barlan; Nerin N Bahceciler; Mübeccel Akdis
Immunological mechanisms of sublingual immunotherapy.
Allergy 2006;61 Suppl 81():11-4.
2006: Johan Verhagen; Mübeccel Akdis; Claudia Traidl-Hoffmann; Peter Schmid-Grendelmeier; Dirk Hijnen; Edward F Knol; Heidrun Behrendt; Kurt Blaser; Cezmi A. Akdis
Absence of T-regulatory cell expression and function in atopic dermatitis skin.
The Journal of allergy and clinical immunology 2006;117(1):176-83.
2006: Cezmi A. Akdis; Kurt Blaser; Mübeccel Akdis
Mechanisms of allergen-specific immunotherapy.
Chemical immunology and allergy 2006;91():195-203.
2006: Mübeccel Akdis; Kurt Blaser; Cezmi A. Akdis
T regulatory cells in allergy.
Chemical immunology and allergy 2006;91():159-73.
2005: Isil B Barlan; Nerin N Bahceciler; Mübeccel Akdis; Cezmi A. Akdis
Role of bacillus Calmette-Guérin as an immunomodulator for the prevention and treatment of allergy and asthma.
Current opinion in allergy and clinical immunology 2005;5(6):552-7.
2005: Mübeccel Akdis; Kurt Blaser; Cezmi A. Akdis
T regulatory cells in allergy: novel concepts in the pathogenesis, prevention, and treatment of allergic diseases.
The Journal of allergy and clinical immunology 2005;116(5):961-8; quiz 969.
2005: Fariba Karamloo; Peter Schmid-Grendelmeier; Fatimah Kussebi; Mübeccel Akdis; Maria Salagianni; Barbara R von Beust; Andrea Reimers; Judith Zumkehr; Lyudmilla Soldatova; Zora Housley-Markovic; Ulrich Müller; Thomas M Kündig; David M Kemeny; Michael D Spangfort; Kurt Blaser; Cezmi A. Akdis
Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes.
European journal of immunology 2005;35(11):3268-76.
2005: Axel Trautmann; Katja Kruger; Mübeccel Akdis; Dietrich Muller-Wening; Ahmet Akkaya; Eva-Bettina Brocker; Kurt Blaser; Cezmi A. Akdis
Apoptosis and loss of adhesion of bronchial epithelial cells in asthma.
International archives of allergy and immunology 2005;138(2):142-50.
2005: Johan Verhagen; Alison Taylor; Kurt Blaser; Mübeccel Akdis; Cezmi A. Akdis
T regulatory cells in allergen-specific immunotherapy.
International reviews of immunology 2005;24(5-6):533-48.
2005: Guro Gafvelin; Sarah Thunberg; Marianne Kronqvist; Hans Grönlund; Reidar Grönneberg; Marita Troye-Blomberg; Mübeccel Akdis; Helmut Fiebig; Ashok Purohit; Friedrich Horak; Jürgen Reisinger; Verena Niederberger; Cezmi A. Akdis; Oliver Cromwell; Gabrielle Pauli; Rudolf Valenta; Marianne van Hage
Cytokine and antibody responses in birch-pollen-allergic patients treated with genetically modified derivatives of the major birch pollen allergen Bet v 1.
International archives of allergy and immunology 2005;138(1):59-66.
2005: Marek Jutel; Mübeccel Akdis; Kurt Blaser; Cezmi A. Akdis
Are regulatory T cells the target of venom immunotherapy?
Current opinion in allergy and clinical immunology 2005;5(4):365-9.
2005: Alison Taylor; Johan Verhagen; Cezmi A. Akdis; Mübeccel Akdis
T regulatory cells and allergy.
Microbes and infection / Institut Pasteur 2005;7(7-8):1049-55.
2005: Esin Aktas; Mübeccel Akdis; Sema Bilgic; Rainer Disch; C S Falk; K Blaser; Cezmi A. Akdis; Günnur Deniz
Different natural killer (NK) receptor expression and immunoglobulin E (IgE) regulation by NK1 and NK2 cells.
Clinical and experimental immunology 2005;140(2):301-9.
2005: Johan Verhagen; Alison Taylor; Mübeccel Akdis; Cezmi A. Akdis
Targets in allergy-directed immunotherapy.
Expert opinion on therapeutic targets 2005;9(2):217-24.
2005: Johan Verhagen; Alison Taylor; Cezmi A. Akdis; Mübeccel Akdis
Advances in allergen-specific immunotherapy.
Expert opinion on biological therapy 2005;5(4):537-44.
2005: Nerin N Bahceciler; Cigdem Arikan; Alison Taylor; Mübeccel Akdis; Kurt Blaser; Isil B Barlan; Cezmi A. Akdis
Impact of sublingual immunotherapy on specific antibody levels in asthmatic children allergic to house dust mites.
International archives of allergy and immunology 2005;136(3):287-94.
2005: Fatimah Kussebi; Fariba Karamloo; Claudio Rhyner; Peter Schmid-Grendelmeier; Maria Salagianni; Christian Mannhart; Mübeccel Akdis; Lyudmilla Soldatova; Zora Markovic-Housley; Barbara R Von Beust; Thomas M Kündig; David M Kemeny; Kurt Blaser; Reto Crameri; Cezmi A. Akdis
A major allergen gene-fusion protein for potential usage in allergen-specific immunotherapy.
The Journal of allergy and clinical immunology 2005;115(2):323-9.
2004: Christian Karagiannidis; Mübeccel Akdis; Päivi Holopainen; Niina J Woolley; Gabriele Hense; Beate Rückert; Pierre-Yves Mantel; Günter Menz; Cezmi A. Akdis; Kurt Blaser; Carsten B Schmidt-Weber
Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma.
The Journal of allergy and clinical immunology 2004;114(6):1425-33.
2004: Cezmi A. Akdis; Kurt Blaser; Mübeccel Akdis
Apoptosis in tissue inflammation and allergic disease.
Current opinion in immunology 2004;16(6):717-23.
2004: Alison Taylor; Johan Verhagen; Cezmi A. Akdis; Mübeccel Akdis
T regulatory cells in allergy and health: a question of allergen specificity and balance.
International archives of allergy and immunology 2004;135(1):73-82.
2004: Cezmi A. Akdis; Kurt Blaser; Mübeccel Akdis
Genes of tolerance.
Allergy 2004;59(9):897-913.
2004: Mübeccel Akdis; Johan Verhagen; Alison Taylor; Fariba Karamloo; Christian Karagiannidis; Reto Crameri; Sarah Thunberg; Günnur Deniz; Rudolf Valenta; Helmut Fiebig; Christian Kegel; Rainer Disch; Carsten B Schmidt-Weber; Kurt Blaser; Cezmi A. Akdis
Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells.
The Journal of experimental medicine 2004;199(11):1567-75.
2004: Cigdem Arikan; Nerin N Bahceciler; Günnur Deniz; Mübeccel Akdis; Tunc Akkoc; Cezmi A. Akdis; Isil B Barlan
Bacillus Calmette-Guérin-induced interleukin-12 did not additionally improve clinical and immunologic parameters in asthmatic children treated with sublingual immunotherapy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(3):398-405.
2004: Mübeccel Akdis; Sven Klunker; Kurt Blaser; Cezmi A. Akdis
Skin homing T cells.
Ernst Schering Research Foundation workshop 2004;(44):15-26.
2003: Cezmi A. Akdis; Fatimah Kussebi; Bali Pulendran; Mübeccel Akdis; Roger Lauener; Carsten B Schmidt-Weber; Sven Klunker; Gülbu Isitmangil; Natasha Hansjee; Thomas A Wynn; Stephanie Dillon; Peter Erb; Gerhard Baschang; Kurt Blaser; Sefik Alkan
Inhibition of T helper 2-type responses, IgE production and eosinophilia by synthetic lipopeptides.
European journal of immunology 2003;33(10):2717-26.
2003: Sven Klunker; Axel Trautmann; Mübeccel Akdis; Johan Verhagen; Peter Schmid-Grendelmeier; Kurt Blaser; Cezmi A. Akdis
A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release IFN-gamma-inducible protein 10, monokine induced by IFN-gamma, and IFN-gamma-inducible alpha-chemoattractant for T cell chemotaxis toward epidermis in atopic dermatitis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):1078-84.
2003: Steffen Kunzmann; Pierre-Yves Mantel; Jan G Wohlfahrt; Mübeccel Akdis; Kurt Blaser; Carsten B Schmidt-Weber
Histamine enhances TGF-beta1-mediated suppression of Th2 responses.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1089-95.
2003: Mübeccel Akdis; Axel Trautmann; Sven Klunker; Isabelle Daigle; Umut C Kucuksezer; Wolfgang Deglmann; Rainer Disch; Kurt Blaser; Cezmi A. Akdis
T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1026-35.
2003: Marek Jutel; Mübeccel Akdis; Ferah Budak; Carmen Aebischer-Casaulta; Maria Wrzyszcz; Kurt Blaser; Cezmi A. Akdis
IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy.
European journal of immunology 2003;33(5):1205-14.
2003: Carmen Casaulta; Martin H Schöni; Michael Weichel; Reto Crameri; Marek Jutel; Isabelle Daigle; Mübeccel Akdis; Kurt Blaser; Cezmi A. Akdis
IL-10 controls Aspergillus fumigatus- and Pseudomonas aeruginosa-specific T-cell response in cystic fibrosis.
Pediatric research 2003;53(2):313-9.
2002: Marek Jutel; Takeshi Watanabe; Mübeccel Akdis; Kurt Blaser; Cezmi A. Akdis
Immune regulation by histamine.
Current opinion in immunology 2002;14(6):735-40.
2002: Günnur Deniz; Mübeccel Akdis; Esin Aktas; Kurt Blaser; Cezmi A. Akdis
Human NK1 and NK2 subsets determined by purification of IFN-gamma-secreting and IFN-gamma-nonsecreting NK cells.
European journal of immunology 2002;32(3):879-84.
2002: Axel Trautmann; Peter Schmid-Grendelmeier; Katja Krüger; Reto Crameri; Mübeccel Akdis; Ahmet Akkaya; Eva-B Bröcker; Kurt Blaser; Cezmi A. Akdis
T cells and eosinophils cooperate in the induction of bronchial epithelial cell apoptosis in asthma.
The Journal of allergy and clinical immunology 2002;109(2):329-37.
2002: Mübeccel Akdis; Axel Trautmann; Kurt Blaser; Cezmi A. Akdis
T cells and effector mechanisms in the pathogenesis of atopic dermatitis.
Current allergy and asthma reports 2002;2(1):1-3.
2001: Axel Trautmann; Mübeccel Akdis; Peter Schmid-Grendelmeier; Rainer Disch; Eva-B Bröcker; Kurt Blaser; Cezmi A. Akdis
Targeting keratinocyte apoptosis in the treatment of atopic dermatitis and allergic contact dermatitis.
The Journal of allergy and clinical immunology 2001;108(5):839-46.
2001: Axel Trautmann; F Altznauer; Mübeccel Akdis; Hans-Uwe Simon; Rainer Disch; Eva-B Bröcker; Kurt Blaser; Cezmi A. Akdis
The differential fate of cadherins during T-cell-induced keratinocyte apoptosis leads to spongiosis in eczematous dermatitis.
The Journal of investigative dermatology 2001;117(4):927-34.
2001: Marek Jutel; T Watanabe; Sven Klunker; Mübeccel Akdis; Olivier Thomet; Józef Malolepszy; Teresa Zak-Nejmark; R Koga; T Kobayashi; Kurt Blaser; Cezmi A. Akdis
Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors.
Nature 2001;413(6854):420-5.
2001: Susanne Vrtala; Kora Hirtenlehner; Markus Susani; Mübeccel Akdis; Fatimah Kussebi; Cezmi A. Akdis; Kurt Blaser; Peter Hufnagl; Bernd R Binder; A Politou; A Pastore; Luca Vangelista; Wolfgang R Sperr; Hans Semper; Peter Valent; Christof Ebner; Dietrich Kraft; Rudolf Valenta
Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):2045-7.
2001: Mübeccel Akdis; Axel Trautmann; Sven Klunker; Kurt Blaser; Cezmi A. Akdis
Cytokine network and dysregulated apoptosis in atopic dermatitis.
Acta odontologica Scandinavica 2001;59(3):178-82.
2001: Axel Trautmann; Mübeccel Akdis; Sven Klunker; Kurt Blaser; Cezmi A. Akdis
Role of apoptosis in atopic dermatitis.
International archives of allergy and immunology 2001;124(1-3):230-2.
2001: Marek Jutel; Sven Klunker; Mübeccel Akdis; J Małolepszy; Olivier Thomet; Teresa Zak-Nejmark; Kurt Blaser; Cezmi A. Akdis
Histamine upregulates Th1 and downregulates Th2 responses due to different patterns of surface histamine 1 and 2 receptor expression.
International archives of allergy and immunology 2001;124(1-3):190-2.
2001: Cezmi A. Akdis; Andrea Joss; Mübeccel Akdis; Kurt Blaser
Mechanism of IL-10-induced T cell inactivation in allergic inflammation and normal response to allergens.
International archives of allergy and immunology 2001;124(1-3):180-2.
2000: Cezmi A. Akdis; Mübeccel Akdis; A Trautmann; Kurt Blaser
Immune regulation in atopic dermatitis.
Current opinion in immunology 2000;12(6):641-6.
2000: Mübeccel Akdis; Sven Klunker; M Schliz; Kurt Blaser; Cezmi A. Akdis
Expression of cutaneous lymphocyte-associated antigen on human CD4(+) and CD8(+) Th2 cells.
European journal of immunology 2000;30(12):3533-41.
2000: Susanne Vrtala; Cezmi A. Akdis; F Budak; Mübeccel Akdis; Kurt Blaser; Dietrich Kraft; Rudolf Valenta
T cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(11):6653-9.
2000: Cezmi A. Akdis; Andrea Joss; Mübeccel Akdis; A Faith; Kurt Blaser
A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase binding.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(12):1666-8.
2000: Axel Trautmann; Mübeccel Akdis; D Kleemann; F Altznauer; Hans-Uwe Simon; T Graeve; M Noll; Eva-B Bröcker; Kurt Blaser; Cezmi A. Akdis
T cell-mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis.
The Journal of clinical investigation 2000;106(1):25-35.
2000: Andrea Joss; Mübeccel Akdis; A Faith; Kurt Blaser; Cezmi A. Akdis
IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway.
European journal of immunology 2000;30(6):1683-90.
1999: Cezmi A. Akdis; Mübeccel Akdis; D Simon; B Dibbert; M Weber; S Gratzl; O Kreyden; Rainer Disch; Brunello Wüthrich; Kurt Blaser; Hans-Uwe Simon
T cells and T cell-derived cytokines as pathogenic factors in the nonallergic form of atopic dermatitis.
The Journal of investigative dermatology 1999;113(4):628-34.
1999: Mübeccel Akdis; Hans-Uwe Simon; L Weigl; O Kreyden; Kurt Blaser; Cezmi A. Akdis
Skin homing (cutaneous lymphocyte-associated antigen-positive) CD8+ T cells respond to superantigen and contribute to eosinophilia and IgE production in atopic dermatitis.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):466-75.
1999: Cezmi A. Akdis; Mübeccel Akdis; Hans-Uwe Simon; Kurt Blaser
Regulation of allergic inflammation by skin-homing T cells in allergic eczema.
International archives of allergy and immunology 1999;118(2-4):140-4.
1999: A Faith; Cezmi A. Akdis; Mübeccel Akdis; Andrea Joss; D Wymann; Kurt Blaser
An altered peptide ligand specifically inhibits Th2 cytokine synthesis by abrogating TCR signaling.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1836-42.
1999: Cezmi A. Akdis; Mübeccel Akdis; D Simon; B Dibbert; M Weber; S Gratzl; O Kreyden; Rainer Disch; Brunello Wüthrich; Kurt Blaser; Hans-Uwe Simon
Role of T cells and cytokines in the intrinsic form of atopic dermatitis.
Current problems in dermatology 1999;28():37-44.
1998: D Wymann; Cezmi A. Akdis; T Blesken; Mübeccel Akdis; Reto Crameri; Kurt Blaser
Enzymatic activity of soluble phospholipase A2 does not affect the specific IgE, IgG4 and cytokine responses in bee sting allergy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(7):839-49.
1998: Cezmi A. Akdis; T Blesken; Mübeccel Akdis; Brunello Wüthrich; Kurt Blaser
Role of interleukin 10 in specific immunotherapy.
The Journal of clinical investigation 1998;102(1):98-106.
1998: U Müller; Cezmi A. Akdis; M Fricker; Mübeccel Akdis; T Blesken; F Bettens; Kurt Blaser
Successful immunotherapy with T-cell epitope peptides of bee venom phospholipase A2 induces specific T-cell anergy in patients allergic to bee venom.
The Journal of allergy and clinical immunology 1998;101(6 Pt 1):747-54.
1998: Cezmi A. Akdis; T Blesken; D Wymann; Mübeccel Akdis; Kurt Blaser
Differential regulation of human T cell cytokine patterns and IgE and IgG4 responses by conformational antigen variants.
European journal of immunology 1998;28(3):914-25.
1997: Mübeccel Akdis; Cezmi A. Akdis; L Weigl; Rainer Disch; Kurt Blaser
Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgE by an IL-13-dominated cytokine pattern: IgG4 counter-regulation by CLA- memory T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(9):4611-9.
1997: Cezmi A. Akdis; T Blesken; Mübeccel Akdis; Sefik Alkan; C H Heusser; Kurt Blaser
Glucocorticoids inhibit human antigen-specific and enhance total IgE and IgG4 production due to differential effects on T and B cells in vitro.
European journal of immunology 1997;27(9):2351-7.
1997: A Faith; Cezmi A. Akdis; Mübeccel Akdis; Hans-Uwe Simon; Kurt Blaser
Defective TCR stimulation in anergized type 2 T helper cells correlates with abrogated p56(lck) and ZAP-70 tyrosine kinase activities.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):53-60.
1997: Cezmi A. Akdis; T Blesken; Mübeccel Akdis; Sefik Alkan; Brunello Wüthrich; C H Heusser; Kurt Blaser
Induction and differential regulation of bee venom phospholipase A2-specific human IgE and IgG4 antibodies in vitro requires allergen-specific and nonspecific activation of T and B cells.
The Journal of allergy and clinical immunology 1997;99(3):345-53.
1996: Cezmi A. Akdis; Mübeccel Akdis; T Blesken; D Wymann; Sefik Alkan; U Müller; Kurt Blaser
Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro.
The Journal of clinical investigation 1996;98(7):1676-83.