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Saverio Bettuzzi

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Disorders

Prostatic Neoplasms

Anatomy

Physiology

Living Beings

Rats

Phenomena

Northern Blotting

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Tea

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Co-Publications
Name
24
Corti, Arnaldo
15
Scaltriti, Maurizio
14
Astancolle, Serenella
13
Caporali, Andrea
9
Davalli, Pierpaola
9
Rizzi, Federica
7
Caccamo, Alessandro
7
D'Arca, Domenico
5
Belloni, Lucia
5
Brausi, Maurizio
4
Scorcioni, Francesca
4
Grassilli, E
3
Maggi, Mario
3
Marverti, Gaetano
3
Moruzzi, Maria Stella

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Publications

TOP 3
Patra S K; Bettuzzi S
Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.
Chayka Olesya; Corvetta Daisy; Dews Michael; Caccamo Alessandro E; Piotrowska Izabela; Santilli Giorgia; Gibson Sian; Sebire Neil J; Himoudi Nourredine; Hogarty Michael D; Anderson John; Bettuzzi Saverio; Thomas-Tikhonenko Andrei; Sala Arturo
Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas.
Rizzi Federica; Caccamo Alessandro Emanuele; Belloni Lucia; Bettuzzi Saverio
Clusterin is a short half-life, poly-ubiquitinated protein, which controls the fate of prostate cancer cells.

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All Publications

2009: Patra S K; Bettuzzi S
Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.
Biochemistry. Biokhimii?a 2009;74(6):613-9.
2009: Chayka Olesya; Corvetta Daisy; Dews Michael; Caccamo Alessandro E; Piotrowska Izabela; Santilli Giorgia; Gibson Sian; Sebire Neil J; Himoudi Nourredine; Hogarty Michael D; Anderson John; Bettuzzi Saverio; Thomas-Tikhonenko Andrei; Sala Arturo
Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas.
Journal of the National Cancer Institute 2009;101(9):663-77.
2009: Rizzi Federica; Caccamo Alessandro Emanuele; Belloni Lucia; Bettuzzi Saverio
Clusterin is a short half-life, poly-ubiquitinated protein, which controls the fate of prostate cancer cells.
Journal of cellular physiology 2009;219(2):314-23.
2009: Bettuzzi Saverio
Conclusions and perspectives.
Advances in cancer research 2009;105():133-50.
2009: Sala Arturo; Bettuzzi Saverio; Pucci Sabina; Chayka Olesya; Dews Michael; Thomas-Tikhonenko Andrei
Regulation of CLU gene expression by oncogenes and epigenetic factors implications for tumorigenesis.
Advances in cancer research 2009;105():115-32.
2009: Panico F; Rizzi F; Fabbri L M; Bettuzzi Saverio; Luppi F
Clusterin (CLU) and lung cancer.
Advances in cancer research 2009;105():63-76.
2009: Rizzi Federica; Bettuzzi Saverio
Clusterin (CLU) and prostate cancer.
Advances in cancer research 2009;105():1-19.
2009: Bettuzzi Saverio; Rizzi Federica
Chapter 5: Nuclear CLU (nCLU) and the fate of the cell.
Advances in cancer research 2009;104():59-88.
2009: Pucci Sabina; Bettuzzi Saverio
Chapter 3: The shifting balance between CLU forms during tumor progression.
Advances in cancer research 2009;104():25-32.
2009: Rizzi Federica; Coletta Mariangela; Bettuzzi Saverio
Chapter 2: Clusterin (CLU): From one gene and two transcripts to many proteins.
Advances in cancer research 2009;104():9-23.
2009: Bettuzzi Saverio
Chapter 1: Introduction.
Advances in cancer research 2009;104():1-8.
2008: Rizzi F; Bettuzzi S
Targeting Clusterin in prostate cancer.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2008;59 Suppl 9():265-74.
2008: Patra S K; Rizzi F; Silva A; Rugina D O; Bettuzzi S
Molecular targets of (-)-epigallocatechin-3-gallate (EGCG): specificity and interaction with membrane lipid rafts.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2008;59 Suppl 9():217-35.
2008: Brausi Maurizio; Rizzi Federica; Bettuzzi Saverio
Chemoprevention of human prostate cancer by green tea catechins: two years later. A follow-up update.
European urology 2008;54(2):472-3.
2008: Patra Samir Kumar; Patra Aditi; Rizzi Federica; Ghosh Tapash Chandra; Bettuzzi Saverio
Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development.
Cancer metastasis reviews 2008;27(2):315-34.
2008: Rizzi Federica; Belloni Lucia; Crafa Pellegrino; Lazzaretti Mirca; Remondini Daniel; Ferretti Stefania; Cortellini Piero; Corti Arnaldo; Bettuzzi Saverio
A novel gene signature for molecular diagnosis of human prostate cancer by RT-qPCR.
PloS one 2008;3(10):e3617.
2007: Moretti Roberta M; Marelli Marina Montagnani; Mai Stefania; Cariboni Anna; Scaltriti Maurizio; Bettuzzi Saverio; Limonta Patrizia
Clusterin isoforms differentially affect growth and motility of prostate cells: possible implications in prostate tumorigenesis.
Cancer research 2007;67(21):10325-33.
2007: Schwab Rebekka; Caccamo Alessandro; Bettuzzi Saverio; Anderson John; Sala Arturo
B-MYB is hypophosphorylated and resistant to degradation in neuroblastoma: implications for cell survival.
Blood cells, molecules & diseases 2007;39(3):263-71.
2007: McCarthy Susan; Caporali Andrea; Enkemann Steve; Scaltriti Maurizio; Eschrich Steve; Davalli Pierpaola; Corti Arnaldo; Lee Alice; Sung Jimmy; Yeatman Timothy J; Bettuzzi Saverio
Green tea catechins suppress the DNA synthesis marker MCM7 in the TRAMP model of prostate cancer.
Molecular oncology 2007;1(2):196-204.
2007: Patra Samir K; Bettuzzi Saverio
Epigenetic DNA-methylation regulation of genes coding for lipid raft-associated components: a role for raft proteins in cell transformation and cancer progression (review).
Oncology reports 2007;17(6):1279-90.
2007: Maioli Margherita; Asara Yolande; Pintus Antonella; Ninniri Stefania; Bettuzzi Saverio; Scaltriti Maurizio; Galimi Francesco; Ventura Carlo
Creating prodynorphin-expressing stem cells alerted for a high-throughput of cardiogenic commitment.
Regenerative medicine 2007;2(2):193-202.
2007: Papini Sandra; Rosellini Alfredo; De Matteis Anna; Campani Daniela; Selli Cesare; Caporali Andrea; Bettuzzi Saverio; Revoltella Roberto P
Establishment of an organotypic in vitro culture system and its relevance to the characterization of human prostate epithelial cancer cells and their stromal interactions.
Pathology, research and practice 2007;203(4):209-16.
2007: Bettuzzi S; Rizzi F; Belloni L
Clinical relevance of the inhibitory effect of green tea catechins (GtCs) on prostate cancer progression in combination with molecular profiling of catechin-resistant tumors: an integrated view.
Polish journal of veterinary sciences 2007;10(1):57-60.
2006: Scaltriti Maurizio; Belloni Lucia; Caporali Andrea; Davalli Pierpaola; Remondini Daniel; Rizzi Federica; Astancolle Serenella; Corti Arnaldo; Bettuzzi Saverio
Molecular classification of green tea catechin-sensitive and green tea catechin-resistant prostate cancer in the TRAMP mice model by quantitative real-time PCR gene profiling.
Carcinogenesis 2006;27(5):1047-53.
2006: Caccamo Alessandro E; Desenzani Silvia; Belloni Lucia; Borghetti Angelo F; Bettuzzi Saverio
Nuclear clusterin accumulation during heat shock response: implications for cell survival and thermo-tolerance induction in immortalized and prostate cancer cells.
Journal of cellular physiology 2006;207(1):208-19.
2006: Bettuzzi Saverio; Brausi Maurizio; Rizzi Federica; Castagnetti Giovanni; Peracchia Giancarlo; Corti Arnaldo
Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study.
Cancer research 2006;66(2):1234-40.
2005: Marverti Gaetano; Giuseppina Monti Maria; Pegg Anthony E; McCloskey Diane E; Bettuzzi Saverio; Ligabue Alessio; Caporali Andrea; D'Arca Domenico; Moruzzi Maria Stella
Spermidine/spermine N1-acetyltransferase transient overexpression restores sensitivity of resistant human ovarian cancer cells to N1,N12-bis(ethyl)spermine and to cisplatin.
Carcinogenesis 2005;26(10):1677-86.
2005: Caccamo A E; Scaltriti M; Caporali A; D'Arca D; Corti A; Corvetta D; Sala A; Bettuzzi S
Ca2+ depletion induces nuclear clusterin, a novel effector of apoptosis in immortalized human prostate cells.
Cell death and differentiation 2005;12(1):101-4.
2004: Scaltriti M; Bettuzzi S; Sharrard R M; Caporali A; Caccamo A E; Maitland N J
Clusterin overexpression in both malignant and nonmalignant prostate epithelial cells induces cell cycle arrest and apoptosis.
British journal of cancer 2004;91(10):1842-50.
2004: Caporali Andrea; Davalli Pierpaola; Astancolle Serenella; D'Arca Domenico; Brausi Maurizio; Bettuzzi Saverio; Corti Arnaldo
The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin over-expression.
Carcinogenesis 2004;25(11):2217-24.
2004: Chen Tingan; Turner Joel; McCarthy Susan; Scaltriti Maurizio; Bettuzzi Saverio; Yeatman Timothy J
Clusterin-mediated apoptosis is regulated by adenomatous polyposis coli and is p21 dependent but p53 independent.
Cancer research 2004;64(20):7412-9.
2004: Scaltriti Maurizio; Santamaria Anna; Paciucci Rosanna; Bettuzzi Saverio
Intracellular clusterin induces G2-M phase arrest and cell death in PC-3 prostate cancer cells1.
Cancer research 2004;64(17):6174-82.
2004: Caccamo Alessandro E; Scaltriti Maurizio; Caporali Andrea; D'Arca Domenico; Scorcioni Francesca; Astancolle Serenella; Mangiola Massimo; Bettuzzi Saverio
Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kDa nuclear isoform of clusterin.
The Biochemical journal 2004;382(Pt 1):157-68.
2004: Crescioli C; Ferruzzi P; Caporali A; Scaltriti M; Bettuzzi S; Mancina R; Gelmini S; Serio M; Villari D; Vannelli G B; Colli E; Adorini L; Maggi M
Inhibition of prostate cell growth by BXL-628, a calcitriol analogue selected for a phase II clinical trial in patients with benign prostate hyperplasia.
European journal of endocrinology / European Federation of Endocrine Societies 2004;150(4):591-603.
2004: Scaltriti Maurizio; Brausi Maurizio; Amorosi Andrea; Caporali Andrea; D'Arca Domenico; Astancolle Serenella; Corti Arnaldo; Bettuzzi Saverio
Clusterin (SGP-2, ApoJ) expression is downregulated in low- and high-grade human prostate cancer.
International journal of cancer. Journal international du cancer 2004;108(1):23-30.
2004: Marverti Gaetano; Monti Maria Giuseppina; Bettuzzi Saverio; Caporali Andrea; Astancolle Serenella; Moruzzi Maria Stella
Cisplatin-resistance modulates the effect of protein synthesis inhibitors on spermidine/spermine N(1)-acetyltransferase expression.
The international journal of biochemistry & cell biology 2004;36(1):123-37.
2003: Caccamo A E; Scaltriti M; Caporali A; D'Arca D; Scorcioni F; Candiano G; Mangiola M; Bettuzzi S
Nuclear translocation of a clusterin isoform is associated with induction of anoikis in SV40-immortalized human prostate epithelial cells.
Annals of the New York Academy of Sciences 2003;1010():514-9.
2003: Bettuzzi Saverio
The new anti-oncogene clusterin and the molecular profiling of prostate cancer progression and prognosis.
Acta bio-medica : Atenei Parmensis 2003;74(2):101-4.
2003: Bettuzzi Saverio; Scaltriti Maurizio; Caporali Andrea; Brausi Maurizio; D'Arca Domenico; Astancolle Serenella; Davalli Pierpaola; Corti Arnaldo
Successful prediction of prostate cancer recurrence by gene profiling in combination with clinical data: a 5-year follow-up study.
Cancer research 2003;63(13):3469-72.
2003: Crescioli C; Ferruzzi P; Caporali A; Mancina R; Comerci A; Muratori M; Scaltriti M; Vannelli G B; Smiroldo S; Mariani R; Villari D; Bettuzzi S; Serio M; Adorini L; Maggi M
Inhibition of spontaneous and androgen-induced prostate growth by a nonhypercalcemic calcitriol analog.
Endocrinology 2003;144(7):3046-57.
2002: Filippi Sandra; Luconi Michaela; Granchi Simone; Vignozzi Linda; Bettuzzi Saverio; Tozzi Paola; Ledda Fabrizio; Forti Gianni; Maggi Mario
Estrogens, but not androgens, regulate expression and functional activity of oxytocin receptor in rabbit epididymis.
Endocrinology 2002;143(11):4271-80.
2002: Bettuzzi Saverio; Scorcioni Francesca; Astancolle Serenella; Davalli Pierpaola; Scaltriti Maurizio; Corti Arnaldo
Clusterin (SGP-2) transient overexpression decreases proliferation rate of SV40-immortalized human prostate epithelial cells by slowing down cell cycle progression.
Oncogene 2002;21(27):4328-34.
2001: Scorcioni F; Corti A; Davalli P; Astancolle S; Bettuzzi S
Manipulation of the expression of regulatory genes of polyamine metabolism results in specific alterations of the cell-cycle progression.
The Biochemical journal 2001;354(Pt 1):217-23.
2001: Marverti G; Bettuzzi S; Astancolle S; Pinna C; Monti M G; Moruzzi M S
Differential induction of spermidine/spermine N1-acetyltransferase activity in cisplatin-sensitive and -resistant ovarian cancer cells in response to N1,N12-bis(ethyl)spermine involves transcriptional and post-transcriptional regulation.
European journal of cancer (Oxford, England : 1990) 2001;37(2):281-9.
2001: Bettuzzi S; Strocchi P; Davalli P; Marinelli M; Furci L; Corti A
Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2001;79(2):133-40.
2000: Astancolle S; Guidetti G; Pinna C; Corti A; Bettuzzi S
Increased levels of clusterin (SGP-2) mRNA and protein accompany rat ventral prostate involution following finasteride treatment.
The Journal of endocrinology 2000;167(2):197-204.
2000: Bettuzzi S; Davalli P; Astancolle S; Carani C; Madeo B; Tampieri A; Corti A;
Tumor progression is accompanied by significant changes in the levels of expression of polyamine metabolism regulatory genes and clusterin (sulfated glycoprotein 2) in human prostate cancer specimens.
Cancer research 2000;60(1):28-34.
1999: Bettuzzi S; Astancolle S; Guidetti G; Moretti M; Tiozzo R; Corti A
Clusterin (SGP-2) gene expression is cell cycle dependent in normal human dermal fibroblasts.
FEBS letters 1999;448(2-3):297-300.
1999: Bettuzzi S; Davalli P; Astancolle S; Pinna C; Roncaglia R; Boraldi F; Tiozzo R; Sharrard M; Corti A
Coordinate changes of polyamine metabolism regulatory proteins during the cell cycle of normal human dermal fibroblasts.
FEBS letters 1999;446(1):18-22.
1998: Pintus G; Tadolini B; Maioli M; Posadino A M; Bennardini F; Bettuzzi S; Ventura C
Heparin inhibits phorbol ester-induced ornithine decarboxylase gene expression in endothelial cells.
FEBS letters 1998;423(1):98-104.
1995: Bettuzzi S; Marinelli M; Strocchi P; Davalli P; Cevolani D; Corti A
Different localization of spermidine/spermine N1-acetyltransferase and ornithine decarboxylase transcripts in the rat kidney.
FEBS letters 1995;377(3):321-4.
1994: Marinelli M; Quaglino D; Bettuzzi S; Strocchi P; Davalli P; Corti A
Increased levels of clusterin mRNA in the ventral prostate of the aging rat are associated to increases in cuboidal (atrophic) cell population and not to changes in apoptotic activity.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1994;72(11-12):515-21.
1994: Bettuzzi S; Strocchi P; Marinelli M; Astancolle S; Davalli P; Corti A
Gene relaxation and aging: changes in the abundance of rat ventral prostate SGP-2 (clusterin) and ornithine decarboxylase mRNAs.
FEBS letters 1994;348(3):255-8.
1993: Zoli M; Ferraguti F; Zini I; Bettuzzi S; Agnati L F
Increases in sulphated glycoprotein-2 mRNA levels in the rat brain after transient forebrain ischemia or partial mesodiencephalic hemitransection.
Brain research. Molecular brain research 1993;18(1-2):163-77.
1992: Monti D; Grassilli E; Troiano L; Cossarizza A; Salvioli S; Barbieri D; Agnesini C; Bettuzzi S; Ingletti M C; Corti A
Senescence, immortalization, and apoptosis. An intriguing relationship.
Annals of the New York Academy of Sciences 1992;673():70-82.
1992: Grassilli E; Bettuzzi S; Troiano L; Ingletti M C; Monti D; Corti A; Franceschi C
SGP-2, apoptosis, and aging.
Annals of the New York Academy of Sciences 1992;663():471-4.
1992: Bettuzzi S; Zoli M; Ferraguti F; Ingletti M C; Agnati L F; Corti A
Regional and cellular distribution within the rat prostate of two mRNA species undergoing opposite regulation by androgens.
The Journal of endocrinology 1992;132(3):361-7.
1992: Bettuzzi S; Robinson A; Fuchs-Young R; Greene G L
Estrogen and progesterone receptor structure and action in breast cancer cells.
Cancer treatment and research 1992;61():301-15.
1991: Grassilli E; Bettuzzi S; Monti D; Ingletti M C; Franceschi C; Corti A
Studies on the relationship between cell proliferation and cell death: opposite patterns of SGP-2 and ornithine decarboxylase mRNA accumulation in PHA-stimulated human lymphocytes.
Biochemical and biophysical research communications 1991;180(1):59-63.
1991: Purrello M; Bettuzzi S; Di Pietro C; Mirabile E; Di Blasi M; Rimini R; Grzeschik K H; Ingletti C; Corti A; Sichel G
The gene for SP-40,40, human homolog of rat sulfated glycoprotein 2, rat clusterin, and rat testosterone-repressed prostate message 2, maps to chromosome 8.
Genomics 1991;10(1):151-6.
1991: Bettuzzi S; Troiano L; Davalli P; Tropea F; Ingletti M C; Grassilli E; Monti D; Corti A; Franceschi C
In vivo accumulation of sulfated glycoprotein 2 mRNA in rat thymocytes upon dexamethasone-induced cell death.
Biochemical and biophysical research communications 1991;175(3):810-5.
1989: Bettuzzi S; Hiipakka R A; Gilna P; Liao S T
Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis.
The Biochemical journal 1989;257(1):293-6.

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