Gloria Cristalli

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Borrmann Thomas; Abdelrahman Aliaa; Volpini Rosaria; Lambertucci Catia; Alksnis Edgars; Gorzalka Simone; Knospe Melanie; Schiedel Anke C; Cristalli Gloria; Müller Christa E
Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.
Maggi Filippo; Bramucci Massimo; Cecchini Cinzia; Coman Maria M; Cresci Alberto; Cristalli Gloria; Lupidi Giulio; Papa Fabrizio; Quassinti Luana; Sagratini Gianni; Vittori Sauro
Composition and biological activity of essential oil of Achillea ligustica All. (Asteraceae) naturalized in central Italy: ideal candidate for anti-cariogenic formulations.
Volpini Rosaria; Mishra Ram Chandra; Kachare Dhuldeo D; Dal Ben Diego; Lambertucci Catia; Antonini Ippolito; Vittori Sauro; Marucci Gabriella; Sokolova Elena; Nistri Andrea; Cristalli Gloria
Adenine-based acyclic nucleotides as novel P2X3 receptor ligands.

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2009: Borrmann Thomas; Abdelrahman Aliaa; Volpini Rosaria; Lambertucci Catia; Alksnis Edgars; Gorzalka Simone; Knospe Melanie; Schiedel Anke C; Cristalli Gloria; Müller Christa E
Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.
Journal of medicinal chemistry 2009;52(19):5974-89.
2009: Maggi Filippo; Bramucci Massimo; Cecchini Cinzia; Coman Maria M; Cresci Alberto; Cristalli Gloria; Lupidi Giulio; Papa Fabrizio; Quassinti Luana; Sagratini Gianni; Vittori Sauro
Composition and biological activity of essential oil of Achillea ligustica All. (Asteraceae) naturalized in central Italy: ideal candidate for anti-cariogenic formulations.
Fitoterapia 2009;80(6):313-9.
2009: Volpini Rosaria; Mishra Ram Chandra; Kachare Dhuldeo D; Dal Ben Diego; Lambertucci Catia; Antonini Ippolito; Vittori Sauro; Marucci Gabriella; Sokolova Elena; Nistri Andrea; Cristalli Gloria
Adenine-based acyclic nucleotides as novel P2X3 receptor ligands.
Journal of medicinal chemistry 2009;52(15):4596-603.
2009: Volpini Rosaria; Dal Ben Diego; Lambertucci Catia; Marucci Gabriella; Mishra Ram Chandra; Ramadori Anna Teresa; Klotz Karl-Norbert; Trincavelli Maria Letizia; Martini Claudia; Cristalli Gloria
Adenosine A2A receptor antagonists: new 8-substituted 9-ethyladenines as tools for in vivo rat models of Parkinson's disease.
ChemMedChem 2009;4(6):1010-9.
2009: Lambertucci Catia; Antonini Ippolito; Buccioni Michela; Dal Ben Diego; Kachare Dhuldeo D; Volpini Rosaria; Klotz Karl-Norbert; Cristalli Gloria
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands.
Bioorganic & medicinal chemistry 2009;17(7):2812-22.
2009: Buccioni Michela; Kandhavelu Meenakshisundaram; Angeli Piero; Cristalli Gloria; Dal Ben Diego; Giardinà Dario; Lambertucci Catia; Lammi Carmen; Volpini Rosaria; Marucci Gabriella
Identification of alpha1-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens.
European journal of pharmacology 2009;602(2-3):388-94.
2009: Cristalli Gloria; Müller Christa E; Volpini Rosaria
Recent developments in adenosine A2A receptor ligands.
Handbook of experimental pharmacology 2009;(193):59-98.
2008: Marucci Gabriella; Finaurini Sara; Buccioni Michela; Lammi Carmen; Kandhavelu Meenakshisundaram; Volpini Rosaria; Ricciutelli Massimo; Angeli Piero; Commandeur Jan N M; Cristalli Gloria
In vitro metabolism studies of new adenosine A 2A receptor antagonists.
Drug metabolism letters 2008;2(4):301-7.
2008: Antonini Ippolito; Volpini Rosaria; Dal Ben Diego; Lambertucci Catia; Cristalli Gloria
Design, synthesis, and biological evaluation of new mitonafide derivatives as potential antitumor drugs.
Bioorganic & medicinal chemistry 2008;16(18):8440-6.
2008: Sharoyan S G; Antonyan A A; Mardanyan S S; Lupidi G; Cuccioloni M; Angeletti M; Cristalli G
Complex of dipeptidyl peptidase II with adenosine deaminase.
Biochemistry. Biokhimii?a 2008;73(8):943-9.
2008: Sagratini Gianni; Caprioli Giovanni; Cristalli Gloria; Giardiná Dario; Ricciutelli Massimo; Volpini Rosaria; Zuo Yanting; Vittori Sauro
Determination of ink photoinitiators in packaged beverages by gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry.
Journal of chromatography. A 2008;1194(2):213-20.
2008: Sagratini Gianni; Cristalli Gloria; Giardinà Dario; Gioventù Giorgio; Maggi Filippo; Ricciutelli Massimo; Vittori Sauro
Alkannin/shikonin mixture from roots of Onosma echioides (L.) L.: extraction method study and quantification.
Journal of separation science 2008;31(6-7):945-52.
2008: Cristalli Gloria; Mátyus Péter; Mohr Peter; Ronsisvalle Giuseppe; de Souza Noel J; Tsantili-Kakoulidou Anna
European medicinal chemistry education: the transformational accomplishments and challenges.
ChemMedChem 2008;3(4):561-3.
2008: Antonini Ippolito; Santoni Giorgio; Lucciarini Roberta; Amantini Consuelo; Dal Ben Diego; Volpini Rosaria; Cristalli Gloria
Synthesis and antitumor evaluation of bis aza-anthracene-9,10-diones and bis aza-anthrapyrazole-6-ones.
Journal of medicinal chemistry 2008;51(4):997-1006.
2008: Cristalli G; Lambertucci C; Marucci G; Volpini R; Dal Ben D
A2A adenosine receptor and its modulators: overview on a druggable GPCR and on structure-activity relationship analysis and binding requirements of agonists and antagonists.
Current pharmaceutical design 2008;14(15):1525-52.
2007: Lambertucci Catia; Cristalli Gloria; Dal Ben Diego; Kachare Dhuldeo D; Bolcato Chiara; Klotz Karl-Norbert; Spalluto Giampiero; Volpini Rosaria
New 2,6,9-trisubstituted adenines as adenosine receptor antagonists: a preliminary SAR profile.
Purinergic signalling 2007;3(4):339-46.
2007: Pugliese Anna Maria; Coppi Elisabetta; Volpini Rosaria; Cristalli Gloria; Corradetti Renato; Jeong Lak Shin; Jacobson Kenneth A; Pedata Felicita
Role of adenosine A3 receptors on CA1 hippocampal neurotransmission during oxygen-glucose deprivation episodes of different duration.
Biochemical pharmacology 2007;74(5):768-79.
2007: Volpini Rosaria; Dal Ben Diego; Lambertucci Catia; Taffi Sara; Vittori Sauro; Klotz Karl-Norbert; Cristalli Gloria
N6-methoxy-2-alkynyladenosine derivatives as highly potent and selective ligands at the human A3 adenosine receptor.
Journal of medicinal chemistry 2007;50(6):1222-30.
2007: Cristalli Gloria; Cacciari Barbara; Dal Ben Diego; Lambertucci Catia; Moro Stefano; Spalluto Giampiero; Volpini Rosaria
Highlights on the development of A(2A) adenosine receptor agonists and antagonists.
ChemMedChem 2007;2(3):260-81.
2007: Klotz Karl-Norbert; Falgner Nico; Kachler Sonja; Lambertucci Catia; Vittori Sauro; Volpini Rosaria; Cristalli Gloria
[3H]HEMADO--a novel tritiated agonist selective for the human adenosine A3 receptor.
European journal of pharmacology 2007;556(1-3):14-8.
2007: Lambertucci Catia; Vittori Sauro; Mishra Ram Chandra; Dal Ben Diego; Klotz Karl-Norbert; Volpini Rosaria; Cristalli Gloria
Synthesis and biological activity of trisubstituted adenines as A 2A adenosine receptor antagonists.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1443-6.
2007: Vittori Sauro; Mishra Ram Chandra; Dal Ben Diego; Kachare Dhuldeo; Lambertucci Catia; Volpini Rosaria; Cristalli Gloria
Synthesis and stability studies of 2',3',5'-tri-O-acetyl-2-amino(-N6-cyclopentyl)-1-deazaadenosines.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1439-42.
2006: Dal Ben Diego; Lambertucci Catia; Taffi Sara; Vittori Sauro; Volpini Rosaria; Cristalli Gloria; Klotz Karl-Norbert
Molecular modelling study of 2-phenylethynyladenosine (PEAdo) derivatives as highly selective A(3) adenosine receptor ligands.
Purinergic signalling 2006;2(4):589-94.
2006: Costanzi Stefano; Vincenzetti Silvia; Cristalli Gloria; Vita Alberto
Human cytidine deaminase: a three-dimensional homology model of a tetrameric metallo-enzyme inferred from the crystal structure of a distantly related dimeric homologue.
Journal of molecular graphics & modelling 2006;25(1):10-6.
2006: Vittori S; Dal Ben D; Lambertucci C; Marucci G; Volpini R; Cristalli G
Antiviral properties of deazaadenine nucleoside derivatives.
Current medicinal chemistry 2006;13(29):3529-52.
2006: Sharoyan Svetlana; Antonyan Alvard; Mardanyan Sona; Lupidi Giulio; Cristalli Gloria
Influence of dipeptidyl peptidase IV on enzymatic properties of adenosine deaminase.
Acta biochimica Polonica 2006;53(3):539-46.
2005: Volpini Rosaria; Costanzi Stefano; Lambertucci Catia; Vittori Sauro; Martini Claudia; Trincavelli M Letizia; Klotz Karl-Norbert; Cristalli Gloria
2- and 8-alkynyl-9-ethyladenines: Synthesis and biological activity at human and rat adenosine receptors.
Purinergic signalling 2005;1(2):173-81.
2005: Pinna Annalisa; Volpini Rosaria; Cristalli Gloria; Morelli Micaela
New adenosine A2A receptor antagonists: actions on Parkinson's disease models.
European journal of pharmacology 2005;512(2-3):157-64.
2005: Cristalli Gloria; Podda Gian Marco; Costanzi Stefano; Lambertucci Catia; Lecchi Anna; Vittori Sauro; Volpini Rosaria; Zighetti Maddalena L; Cattaneo Marco
Effects of 5'-phosphate derivatives of 2-hexynyl adenosine and 2-phenylethynyl adenosine on responses of human platelets mediated by P2Y receptors.
Journal of medicinal chemistry 2005;48(8):2763-6.
2005: Gorzalka Simone; Vittori Sauro; Volpini Rosaria; Cristalli Gloria; von Kügelgen Ivar; Müller Christa E
Evidence for the functional expression and pharmacological characterization of adenine receptors in native cells and tissues.
Molecular pharmacology 2005;67(3):955-64.
2005: Vittori S; Volpini R; Lambertucci C; Taffi S; Klotz K N; Cristalli G
2-substituted 5'-N-methylcarboxamidoadenosine (MECA) derivatives as A3 adenosine receptor ligands.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):935-8.
2005: Costanzi S; Lambertucci C; Portino F R; Volpini R; Vittori S; Cristalli G
Ring opening reactions: synthesis of AICAR analogs as potential antimetabolite agents.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):415-8.
2004: Saboury Ali Akbar; Bagheri Soghra; Ataie Ghasem; Amanlou Masoud; Moosavi-Movahedi Ali Akbar; Hakimelahi Gholam Hossein; Cristalli Gloria; Namaki Saeid
Binding properties of adenosine deaminase interacted with theophylline.
Chemical & pharmaceutical bulletin 2004;52(10):1179-82.
2004: Woutersen Sander; Cristalli Gloria
Strong enhancement of vibrational relaxation by Watson-Crick base pairing.
The Journal of chemical physics 2004;121(11):5381-6.
2004: Ataie G; Safarian S; Divsalar A; Saboury A A; Moosavi-Movahedi A A; Ranjbar B; Cristalli G; Mardanian S
Kinetic and structural analysis of the inhibition of adenosine deaminase by acetaminophen.
Journal of enzyme inhibition and medicinal chemistry 2004;19(1):71-8.
2004: D'Ambrosi Nadia; Costanzi Stefano; Angelini Daniela F; Volpini Rosaria; Sancesario Giuseppe; Cristalli Gloria; Volonté Cinzia
2-ClATP exerts anti-tumoural actions not mediated by P2 receptors in neuronal and glial cell lines.
Biochemical pharmacology 2004;67(4):621-30.
2004: Vittori S; Costanzi S; Lambertucci C; Portino F R; Taffi S; Volpini R; Klotz K N; Cristalli G
A2B adenosine receptor agonists: synthesis and biological evaluation of 2-phenylhydroxypropynyl adenosine and NECA derivatives.
Nucleosides, nucleotides & nucleic acids 2004;23(1-2):471-81.
2003: Vincenzetti Silvia; De Sanctis Giampiero; Costanzi Stefano; Cristalli Gloria; Mariani Pierluigi; Mei Giampiero; Neuhard Jan; Natalini Paolo; Polzonetti Valeria; Vita Alberto
Functional properties of subunit interactions in human cytidine deaminase.
Protein engineering 2003;16(12):1055-61.
2003: Klotz Karl-Norbert; Kachler Sonja; Lambertucci Catia; Vittori Sauro; Volpini Rosaria; Cristalli Gloria
9-Ethyladenine derivatives as adenosine receptor antagonists: 2- and 8-substitution results in distinct selectivities.
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(6):629-34.
2003: Costanzi S; Vincenzetti S; Vita A; Lambertucci C; Taffi S; Volpini R; Vittori S; Cristalli G
Human cytidine deaminase: understanding the catalytic mechanism.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1539-43.
2003: Vincenzetti S; Costanzi S; Cristalli G; Mariani P; Quadrini B; Cammertoni N; Vita A
Intersubunit interactions in human cytidine deaminase.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1535-8.
2003: Vittori Sauro; Salvatori Daniela; Volpini Rosaria; Vincenzetti Silvia; Vita Alberto; Taffi Sara; Costanzi Stefano; Lambertucci Catia; Cristalli Gloria
Deaza- and deoxyadenosine derivatives: synthesis and inhibition of animal viruses as human infection models.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):877-81.
2003: Lambertucci C; Volpini R; Costanzi S; Taffi S; Vittori S; Cristalli G
2-Phenylhydroxypropynyladenosine derivatives as high potent agonists at A2B adenosine receptor subtype.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):809-12.
2003: Cristalli Gloria; Costanzi Stefano; Lambertucci Catia; Taffi Sara; Vittori Sauro; Volpini Rosaria
Purine and deazapurine nucleosides: synthetic approaches, molecular modelling and biological activity.
Farmaco (Società chimica italiana : 1989) 2003;58(3):193-204.
2003: Costanzi Stefano; Lambertucci Catia; Vittori Sauro; Volpini Rosaria; Cristalli Gloria
2- and 8-alkynyladenosines: conformational studies and docking to human adenosine A3 receptor can explain their different biological behavior.
Journal of molecular graphics & modelling 2003;21(4):253-62.
2003: Volpini Rosaria; Costanzi Stefano; Vittori Sauro; Cristalli Gloria; Klotz Karl-Norbert
Medicinal chemistry and pharmacology of A2B adenosine receptors.
Current topics in medicinal chemistry 2003;3(4):427-43.
2003: Cristalli Gloria; Lambertucci Catia; Taffi Sara; Vittori Sauro; Volpini Rosaria
Medicinal chemistry of adenosine A2A receptor agonists.
Current topics in medicinal chemistry 2003;3(4):387-401.
2002: Salvatori Daniela; Volpini Rosaria; Vincenzetti Silvia; Vita Alberto; Costanzi Stefano; Lambertucci Catia; Cristalli Gloria; Vittori Sauro
Adenine and deazaadenine nucleoside and deoxynucleoside analogues: inhibition of viral replication of sheep MVV (in vitro model for HIV) and bovine BHV-1.
Bioorganic & medicinal chemistry 2002;10(9):2973-80.
2002: Mardanyan S S; Sharoyan S G; Antonyan A A; Lupidi G; Cristalli G
Interaction of adenosine deaminase with inhibitors. Chemical modification by diethyl pyrocarbonate.
Biochemistry. Biokhimii?a 2002;67(7):770-7.
2002: Volpini Rosaria; Costanzi Stefano; Lambertucci Catia; Taffi Sara; Vittori Sauro; Klotz Karl-Norbert; Cristalli Gloria
N(6)-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting point for searching A(2B) ligands.
Journal of medicinal chemistry 2002;45(15):3271-9.
2002: Volpini Rosaria; Costanzi Stefano; Lambertucci Catia; Vittori Sauro; Cristalli Gloria
Purine nucleosides bearing 1-alkynyl chains as adenosine receptor agonists.
Current pharmaceutical design 2002;8(26):2285-98.
2001: Volpini R; Costanzi S; Lambertucci C; Vittori S; Klotz K; Lorenzen A; Cristalli G
Introduction of alkynyl chains on C-8 of adenosine led to very selective antagonists of the A(3) adenosine receptor.
Bioorganic & medicinal chemistry letters 2001;11(14):1931-4.
2001: Volpini R; Costanzi S; Lambertucci C; Vittori S; Cristalli G
Synthetic procedure for the preparation of novel potent and selective A3 adenosine receptor radioligands.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):775-9.
2001: Vittori S; Costanzi S; Lambertucci C; Volpini R; Cristalli G
Coupling of 2,6-disubstituted purines to ribose-modified sugars.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):771-4.
2001: Lambertucci C; Costanzi S; Vittori S; Volpini R; Cristalli G
Synthesis and adenosine receptor affinity and potency of 8-alkynyl derivatives of adenosine.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):1153-7.
2001: Costanzi S; Lambertucci C; Volpini R; Vittori S; Lupidi G; Cristalli G
3'-deoxyribofuranose derivatives of 1-deaza and 3-deaza-adenosine and their activity as adenosine deaminase inhibitors.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):1037-41.
2001: Mardanyan S; Sharoyan S; Antonyan A; Armenyan A; Cristalli G; Lupidi G
Tryptophan environment in adenosine deaminase. I. Enzyme modification with N-bromosuccinimide in the presence of adenosine and EHNA analogues.
Biochimica et biophysica acta 2001;1546(1):185-95.
2001: Cristalli G; Costanzi S; Lambertucci C; Lupidi G; Vittori S; Volpini R; Camaioni E
Adenosine deaminase: functional implications and different classes of inhibitors.
Medicinal research reviews 2001;21(2):105-28.
2000: Vittori S; Lorenzen A; Stannek C; Costanzi S; Volpini R; IJzerman A P; Kunzel J K; Cristalli G
N-cycloalkyl derivatives of adenosine and 1-deazaadenosine as agonists and partial agonists of the A(1) adenosine receptor.
Journal of medicinal chemistry 2000;43(2):250-60.
1999: Volpini R; Camaioni E; Costanzi S; Vittori S; Klotz K N; Cristalli G
Synthesis of di- and tri-substituted adenosine derivatives and their affinities at human adenosine receptor subtypes.
Nucleosides & nucleotides 1999;18(11-12):2511-20.
1999: Klotz K N; Camaioni E; Volpini R; Kachler S; Vittori S; Cristalli G
2-Substituted N-ethylcarboxamidoadenosine derivatives as high-affinity agonists at human A3 adenosine receptors.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(2):103-8.
1999: Nandanan E; Camaioni E; Jang S Y; Kim Y C; Cristalli G; Herdewijn P; Secrist J A; Tiwari K N; Mohanram A; Harden T K; Boyer J L; Jacobson K A
Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists.
Journal of medicinal chemistry 1999;42(9):1625-38.
1999: Bergman A M; Cristalli G; Vittori S; Wang J; Eriksson S; Peters G J
Biological activity of 1-deazapurine nucleosides: role of deoxycytidine kinase?
Nucleosides & nucleotides 1999;18(4-5):897-8.
1999: Vittori S; Camaioni E; Costanzi S; Volpini R; Klotz K N; Cristalli G
Synthesis and receptor affinity of polysubstituted adenosines.
Nucleosides & nucleotides 1999;18(4-5):739-40.
1998: Lupidi G; Marmocchi F; Cristalli G
Inhibition studies on membrane adenosine deaminase from human placenta.
Biochemistry and molecular biology international 1998;46(6):1071-80.
1998: Barbieri D; Franceschi C; Camaioni E; Costanzi S; Vittori S; Volpini R; Cristalli G
Modulation of apoptosis in human lymphocytes by adenosine analogues.
Bioorganic & medicinal chemistry letters 1998;8(18):2533-8.
1998: Baraldi P G; Cacciari B; Pineda de Las Infantas M J; Romagnoli R; Spalluto G; Volpini R; Costanzi S; Vittori S; Cristalli G; Melman N; Park K S; Ji X D; Jacobson K A
Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5'-N-ethyluronamide as A1 and A3 adenosine receptor agonists.
Journal of medicinal chemistry 1998;41(17):3174-85.
1998: Camaioni E; Costanzi S; Vittori S; Volpini R; Klotz K N; Cristalli G
New substituted 9-alkylpurines as adenosine receptor ligands.
Bioorganic & medicinal chemistry 1998;6(5):523-33.
1997: Camaioni E; Di Francesco E; Vittori S; Volpini R; Cristalli G
Adenosine receptor agonists: synthesis and biological evaluation of the diastereoisomers of 2-(3-hydroxy-3-phenyl-1-propyn-1-yl)NECA.
Bioorganic & medicinal chemistry 1997;5(12):2267-75.
1997: Lupidi G; Marmocchi F; Venardi G; Cristalli G
Functional residues at the active site of bovine brain adenosine deaminase.
Biochemistry and molecular biology international 1997;43(6):1339-52.
1997: Volpini R; Camaioni E; Lupidi G; Vittori S; Cristalli G
Adenosine deaminase inhibitors: synthesis, diastereoisomeric resolution and biological activity of 1-(2-hydroxy-3-nonyl)-1,2,4-triazole-3-carboxamide.
Farmaco (Società chimica italiana : 1989) 1997;52(6-7):429-33.
1996: Vittori S; Camaioni E; Di Francesco E; Volpini R; Monopoli A; Dionisotti S; Ongini E; Cristalli G
2-alkenyl and 2-alkyl derivatives of adenosine and adenosine-5'-N-ethyluronamide: different affinity and selectivity of E- and Z-diastereomers at A2A adenosine receptors.
Journal of medicinal chemistry 1996;39(21):4211-7.
1995: Marongiu M E; Pani A; Tinti E; Grifantini M; Franchetti P; Cristalli G; La Colla P
Enhancement of the anti-HIV-1 activity of ddAdo by coformycin, EHNA and deaza-EHNA derivatives.
The new microbiologica : official journal of the Italian Society for Medical, Odontoiatric, and Clinical Microbiology (SIMMOC) 1995;18(4):359-70.
1995: Cristalli G; Vittori S; Eleuteri A; Volpini R; Camaioni E; Lupidi G; Mahmood N; Bevilacqua F; Palù G
Synthesis and biological evaluation of N6-cycloalkyl derivatives of 1-deazaadenine nucleosides: a new class of anti-human immunodeficiency virus agents.
Journal of medicinal chemistry 1995;38(20):4019-25.
1995: Cristalli G; Camaioni E; Vittori S; Volpini R; Borea P A; Conti A; Dionisotti S; Ongini E; Monopoli A
2-Aralkynyl and 2-heteroalkynyl derivatives of adenosine-5'-N-ethyluronamide as selective A2a adenosine receptor agonists.
Journal of medicinal chemistry 1995;38(9):1462-72.
1995: Siddiqi S M; Jacobson K A; Esker J L; Olah M E; Ji X D; Melman N; Tiwari K N; Secrist J A; Schneller S W; Cristalli G
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
Journal of medicinal chemistry 1995;38(7):1174-88.
1994: Monopoli A; Conti A; Dionisotti S; Casati C; Camaioni E; Cristalli G; Ongini E
Pharmacology of the highly selective A1 adenosine receptor agonist 2-chloro-N6-cyclopentyladenosine.
Arzneimittel-Forschung 1994;44(12):1305-12.
1994: Monopoli A; Conti A; Zocchi C; Casati C; Volpini R; Cristalli G; Ongini E
Pharmacology of the new selective A2a adenosine receptor agonist 2-hexynyl-5'-N-ethylcarboxamidoadenosine.
Arzneimittel-Forschung 1994;44(12):1296-304.
1994: Cristalli G; Vittori S; Thompson R D; Padgett W L; Shi D; Daly J W; Olsson R A
Inhibition of platelet aggregation by adenosine receptor agonists.
Naunyn-Schmiedeberg's archives of pharmacology 1994;349(6):644-50.
1994: Cristalli G; Volpini R; Vittori S; Camaioni E; Monopoli A; Conti A; Dionisotti S; Zocchi C; Ongini E
2-Alkynyl derivatives of adenosine-5'-N-ethyluronamide: selective A2 adenosine receptor agonists with potent inhibitory activity on platelet aggregation.
Journal of medicinal chemistry 1994;37(11):1720-6.
1994: Cristalli G; Eleuteri A; Volpini R; Vittori S; Camaioni E; Lupidi G
Adenosine deaminase inhibitors: synthesis and structure-activity relationships of 2-hydroxy-3-nonyl derivatives of azoles.
Journal of medicinal chemistry 1994;37(1):201-5.
1992: Lupidi G; Marmocchi F; Falasca M; Venardi G; Cristalli G; Grifantini M; Whitehead E; Riva F
Adenosine deaminase from Saccharomyces cerevisiae: kinetics and interaction with transition and ground state inhibitors.
Biochimica et biophysica acta 1992;1122(3):311-6.
1992: Cristalli G; Eleuteri A; Vittori S; Volpini R; Lohse M J; Klotz K N
2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors.
Journal of medicinal chemistry 1992;35(13):2363-8.
1992: Lupidi G; Falasca M; Marmocchi F; Venardi G; Cristalli G; Riva F
Adenosine deaminase from bovine brain: purification and partial characterization.
Biochemistry international 1992;26(6):1053-63.
1991: Cristalli G; Vittori S; Eleuteri A; Grifantini M; Volpini R; Lupidi G; Capolongo L; Pesenti E
Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity.
Journal of medicinal chemistry 1991;34(7):2226-30.
1991: Cristalli G; Eleuteri A; Franchetti P; Grifantini M; Vittori S; Lupidi G
Adenosine deaminase inhibitors: synthesis and structure-activity relationships of imidazole analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Journal of medicinal chemistry 1991;34(3):1187-92.
1991: Grifantini M; Cristalli G; Franchetti P; Vittori S
Adenosine derivatives as agonists of adenosine receptors.
Farmaco (Società chimica italiana : 1989) 1991;46(1 Suppl):161-9.
1990: Franchetti P; Cristalli G; Grifantini M; Cappellacci L; Vittori S; Nocentini G
Synthesis and antitumor activity of 2-beta-D-ribofuranosyloxazole-4-carboxamide (oxazofurin).
Journal of medicinal chemistry 1990;33(10):2849-52.
1989: Klotz K N; Lohse M J; Schwabe U; Cristalli G; Vittori S; Grifantini M
2-Chloro-N6-[3H]cyclopentyladenosine ([3H]CCPA)--a high affinity agonist radioligand for A1 adenosine receptors.
Naunyn-Schmiedeberg's archives of pharmacology 1989;340(6):679-83.
1989: Cristalli G; Franchetti P; Grifantini M; Nocentini G; Vittori S
3,7-Dideazapurine nucleosides. Synthesis and antitumor activity of 1-deazatubercidin and 2-chloro-2'-deoxy-3,7-dideazaadenosine.
Journal of medicinal chemistry 1989;32(7):1463-6.
1988: Cristalli G; Franchetti P; Grifantini M; Vittori S; Klotz K N; Lohse M J
Adenosine receptor agonists: synthesis and biological evaluation of 1-deaza analogues of adenosine derivatives.
Journal of medicinal chemistry 1988;31(6):1179-83.
1988: Lohse M J; Klotz K N; Schwabe U; Cristalli G; Vittori S; Grifantini M
2-Chloro-N6-cyclopentyladenosine: a highly selective agonist at A1 adenosine receptors.
Naunyn-Schmiedeberg's archives of pharmacology 1988;337(6):687-9.
1988: Cristalli G; Franchetti P; Grifantini M; Vittori S; Lupidi G; Riva F; Bordoni T; Geroni C; Verini M A
Adenosine deaminase inhibitors. Synthesis and biological activity of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Journal of medicinal chemistry 1988;31(2):390-3.
1988: Antonini I; Claudi F; Cristalli G; Franchetti P; Grifantini M; Martelli S
Heterocyclic quinones with potential antitumor activity. 2. Synthesis and antitumor activity of some benzimidazole-4,7-dione derivatives.
Journal of medicinal chemistry 1988;31(1):260-4.
1987: Cristalli G; Franchetti P; Grifantini M; Vittori S; Bordoni T; Geroni C
Improved synthesis and antitumor activity of 1-deazaadenosine.
Journal of medicinal chemistry 1987;30(9):1686-8.
1987: Silvotti L; Piedimonte G; Cristalli G; Grifantini M; Galiotta P; Cattabeni F; Cantoni O
The effect of deazaadenosine analogues on the proliferation rate of cultured Vero cells.
Pharmacological research communications 1987;19(5):359-66.
1986: Cristalli G; Franchetti P; Grifantini M; Ripa S
2,2'-Bipyridyl-6-carboxamidoximes with potential antitumor and antimicrobial properties.
Il Farmaco; edizione scientifica 1986;41(7):499-507.
1986: Claudi F; Cristalli G; Martelli S; Perlini V; Massi M; Venturi F
Synthesis and dopaminergic activity of trans-6-methyl-7a,8,9,10,11,11a-hexahydro-7H-pyrrolo[3,2,1-gh]- 4,7-phenanthroline and trans-1,2,3,4,4a,5,6,10b-octahydro-4,7-phenanthroline derivatives.
Journal of medicinal chemistry 1986;29(6):1061-5.
1986: Antonini I; Cristalli G; Franchetti P; Grifantini M; Martelli S; Filippeschi S
2,2'-Bipyridyl-6-carbothioamide derivatives as potential antitumor agents.
Il Farmaco; edizione scientifica 1986;41(5):346-54.
1986: Cantoni O; Piedimonte G; Sestili P; Balduini W; Cristalli G; Grifantini M; Cattabeni F
1,3 dideazaadenosine is a mitogen for cultured mammalian cells.
Pharmacological research communications 1986;18(4):333-42.
1985: Cantoni O; Sestili P; Balduini W; Cristalli G; Grifantini M; Cattabeni F
Inhibition of nucleic acids and protein synthesis by deazaadenosine derivatives: a study on structure-activity relationships.
Pharmacological research communications 1985;17(12):1087-94.
1985: Klotz K N; Cristalli G; Grifantini M; Vittori S; Lohse M J
Photoaffinity labeling of A1-adenosine receptors.
The Journal of biological chemistry 1985;260(27):14659-64.
1985: Lupidi G; Cristalli G; Marmocchi F; Riva F; Grifantini M
Inhibition of adenosine deaminase from several sources by deaza derivatives of adenosine and EHNA.
Journal of enzyme inhibition 1985;1(1):67-75.
1984: Antonini I; Cristalli G; Franchetti P; Grifantini M; Martelli S; Lupidi G; Riva F
Adenosine deaminase inhibitors. Synthesis of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Journal of medicinal chemistry 1984;27(3):274-8.
1982: Lupidi G; Riva F; Cristalli G; Grifantini M
Inhibition of adenosine deaminase by deaza derivatives of adenosine and purine riboside.
The Italian journal of biochemistry 1982;31(6):396-403.
1982: Antonini I; Claudi F; Cristalli G; Franchetti P; Grifantini M; Martelli S
Synthesis of 4-amino-1-beta-D-ribofuranosyl-1H-pyrrolo[2,3-b]pyridine (1-deazatubercidin) as a potential antitumor agent.
Journal of medicinal chemistry 1982;25(10):1258-61.
1981: Antonini I; Claudi F; Cristalli G; Franchetti P; Grifantini M; Martelli S
N*-N*-S* tridentate ligand system as potential antitumor agents.
Journal of medicinal chemistry 1981;24(10):1181-4.

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