FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Rui-Dong Duan

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Concepts & Ideas

Disorders

Colonic Neoplasms

Co-author Network

Publications

TOP 3
Ping Zhang; Yajun Cheng; Rui-Dong Duan
Ursolic acid inhibits acid sphingomyelinase in intestinal cells.
Rui-Dong Duan
Physiological functions and clinical implications of sphingolipids in the gut.
Yao Zhang; Yajun Cheng; Gert H Hansen; Lise-Lotte Niels-Christiansen; Frank Koentgen; Lena Ohlsson; Ake Nilsson; Rui-Dong Duan
Crucial role of alkaline sphingomyelinase in sphingomyelin digestion: a study on enzyme knockout mice.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Rui-Dong Duan (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Ping Zhang; Yajun Cheng; Rui-Dong Duan
Ursolic acid inhibits acid sphingomyelinase in intestinal cells.
Phytotherapy research : PTR 2013;27(2):173-8.
2011: Rui-Dong Duan
Physiological functions and clinical implications of sphingolipids in the gut.
Journal of digestive diseases 2011;12(2):60-70.
2011: Yao Zhang; Yajun Cheng; Gert H Hansen; Lise-Lotte Niels-Christiansen; Frank Koentgen; Lena Ohlsson; Ake Nilsson; Rui-Dong Duan
Crucial role of alkaline sphingomyelinase in sphingomyelin digestion: a study on enzyme knockout mice.
Journal of lipid research 2011;52(4):771-81.
2010: Dan Feng; Lena Ohlsson; Wenhua Ling; Ake Nilsson; Rui-Dong Duan
Generating ceramide from sphingomyelin by alkaline sphingomyelinase in the gut enhances sphingomyelin-induced inhibition of cholesterol uptake in Caco-2 cells.
Digestive diseases and sciences 2010;55(12):3377-83.
2010: Lena Ohlsson; H Burling; Rui-Dong Duan; Ake Nilsson
Effects of a sphingolipid-enriched dairy formulation on postprandial lipid concentrations.
European journal of clinical nutrition 2010;64(11):1344-9.
2010: Jianxin Duan; Jun Wu; Yajun Cheng; Rui-Dong Duan
Understanding the molecular activity of alkaline sphingomyelinase (NPP7) by computer modeling.
Biochemistry 2010;49(42):9096-105.
2010: Gloria Rodrigo; Giovanna R Almanza; Yajun Cheng; Jiangnan Peng; Mark Hamann; Rui-Dong Duan; Björn Akesson
Antiproliferative effects of curcuphenol, a sesquiterpene phenol.
Fitoterapia 2010;81(7):762-6.
2010: Lena Ohlsson; Erik Hertervig; Bo Ag Jönsson; Rui-Dong Duan; Lena Nyberg; Rikard Svernlöv; Ake Nilsson
Sphingolipids in human ileostomy content after meals containing milk sphingomyelin.
The American journal of clinical nutrition 2010;91(3):672-8.
2010: Dan Feng; Wen-Hua Ling; Rui-Dong Duan
Lycopene suppresses LPS-induced NO and IL-6 production by inhibiting the activation of ERK, p38MAPK, and NF-kappaB in macrophages.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2010;59(2):115-21.
2010: Dan Feng; Lena Ohlsson; Rui-Dong Duan
Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression.
Lipids in health and disease 2010;9():40.
2009: Yajun Cheng; Fuli Liu; Jun Wu; Yao Zhang; Ake Nilsson; Rui-Dong Duan
Ezetimibe inhibits expression of acid sphingomyelinase in liver and intestine.
Lipids 2009;44(10):897-906.
2009: Jian-Jun Liu; Rui-Dong Duan
LY294002 enhances boswellic acid-induced apoptosis in colon cancer cells.
Anticancer research 2009;29(8):2987-91.
2009: David Andersson; Knut Kotarsky; Jun Wu; William W Agace; Rui-Dong Duan
Expression of alkaline sphingomyelinase in yeast cells and anti-inflammatory effects of the expressed enzyme in a rat colitis model.
Digestive diseases and sciences 2009;54(7):1440-8.
2009: Yao Zhang; Rui-Dong Duan
Boswellic acid inhibits expression of acid sphingomyelinase in intestinal cells.
Lipids in health and disease 2009;8():51.
2008: Ping Zhang; Baixiang Li; Shuying Gao; Rui-Dong Duan
Dietary sphingomyelin inhibits colonic tumorigenesis with an up-regulation of alkaline sphingomyelinase expression in ICR mice.
Anticancer research 2008;28(6A):3631-5.
2008: Marité Cárdenas; Karin Schillén; Viveka Alfredsson; Rui-Dong Duan; Lena Nyberg; Thomas Arnebrant
Solubilization of sphingomyelin vesicles by addition of a bile salt.
Chemistry and physics of lipids 2008;151(1):10-7.
2008: David Andersson; Yajun Cheng; Rui-Dong Duan
Ursolic acid inhibits the formation of aberrant crypt foci and affects colonic sphingomyelin hydrolyzing enzymes in azoxymethane-treated rats.
Journal of cancer research and clinical oncology 2008;134(1):101-7.
2007: Y Cheng; J Wu; Eva Hertervig; S Lindgren; D Duan; A Nilsson; Rui-Dong Duan
Identification of aberrant forms of alkaline sphingomyelinase (NPP7) associated with human liver tumorigenesis.
British journal of cancer 2007;97(10):1441-8.
2007: Lena Ohlsson; Carina Palmberg; Rui-Dong Duan; Maria Olsson; Tomas Bergman; Ake Nilsson
Purification and characterization of human intestinal neutral ceramidase.
Biochimie 2007;89(8):950-60.
2007: Yajun Cheng; Agnieszka Kozubek; Lena Ohlsson; Berit Sternby; Rui-Dong Duan
Curcumin decreases acid sphingomyelinase activity in colon cancer Caco-2 cells.
Planta medica 2007;73(8):725-30.
2007: Rui-Dong Duan; Yajun Cheng; Bo A G Jönsson; Lena Ohlsson; Andreas Herbst; Lena Hellström-Westas; Ake Nilsson
Human meconium contains significant amounts of alkaline sphingomyelinase, neutral ceramidase, and sphingolipid metabolites.
Pediatric research 2007;61(1):61-6.
2006: Fuli Liu; Yajun Cheng; Jun Wu; Horst-Dietmar Tauschel; Rui-Dong Duan
Ursodeoxycholic acid differentially affects three types of sphingomyelinase in human colon cancer Caco 2 cells.
Cancer letters 2006;235(1):141-6.
2006: Rui-Dong Duan
Alkaline sphingomyelinase: an old enzyme with novel implications.
Biochimica et biophysica acta 2006;1761(3):281-91.
2006: Jun Wu; Ake Nilsson; Bo A G Jönsson; Hanna Stenstad; William W Agace; Yajun Cheng; Rui-Dong Duan
Intestinal alkaline sphingomyelinase hydrolyses and inactivates platelet-activating factor by a phospholipase C activity.
The Biochemical journal 2006;394(Pt 1):299-308.
2006: Ake Nilsson; Rui-Dong Duan
Absorption and lipoprotein transport of sphingomyelin.
Journal of lipid research 2006;47(1):154-71.
2005: Jun Wu; Yajun Cheng; Bo A G Jönsson; Ake Nilsson; Rui-Dong Duan
Acid sphingomyelinase is induced by butyrate but does not initiate the anticancer effect of butyrate in HT29 and HepG2 cells.
Journal of lipid research 2005;46(9):1944-52.
2005: Jun Wu; Yajun Cheng; Carina Palmberg; Tomas Bergman; Ake Nilsson; Rui-Dong Duan
Cloning of alkaline sphingomyelinase from rat intestinal mucosa and adjusting of the hypothetical protein XP_221184 in GenBank.
Biochimica et biophysica acta 2005;1687(1-3):94-102.
2005: Jun Wu; Gert H Hansen; Ake Nilsson; Rui-Dong Duan
Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis.
The Biochemical journal 2005;386(Pt 1):153-60.
2005: Rui-Dong Duan
Anticancer compounds and sphingolipid metabolism in the colon.
In vivo (Athens, Greece) 2005;19(1):293-300.
2004: Marie E Olsson; Karl-Erik Gustavsson; Staffan Andersson; Ake Nilsson; Rui-Dong Duan
Inhibition of cancer cell proliferation in vitro by fruit and berry extracts and correlations with antioxidant levels.
Journal of agricultural and food chemistry 2004;52(24):7264-71.
2004: Jun Wu; Fuli Liu; Ake Nilsson; Rui-Dong Duan
Pancreatic trypsin cleaves intestinal alkaline sphingomyelinase from mucosa and enhances the sphingomyelinase activity.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(5):G967-73.
2004: Maria Olsson; Rui-Dong Duan; Lena Ohlsson; Ake Nilsson
Rat intestinal ceramidase: purification, properties, and physiological relevance.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(4):G929-37.
2004: Jun Wu; Yajun Cheng; Ake Nilsson; Rui-Dong Duan
Identification of one exon deletion of intestinal alkaline sphingomyelinase in colon cancer HT-29 cells and a differentiation-related expression of the wild-type enzyme in Caco-2 cells.
Carcinogenesis 2004;25(8):1327-33.
2004: Yajun Cheng; Lena Ohlsson; Rui-Dong Duan
Psyllium and fat in diets differentially affect the activities and expressions of colonic sphingomyelinases and caspase in mice.
The British journal of nutrition 2004;91(5):715-23.
2003: Rui-Dong Duan; Tomas Bergman; Ning Xu; Jun Wu; Yajun Cheng; Jianxin Duan; Sven Nelander; Carina Palmberg; Ake Nilsson
Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family.
The Journal of biological chemistry 2003;278(40):38528-36.
2003: Eva Hertervig; Ake Nilsson; Yajun Cheng; Rui-Dong Duan
Purified intestinal alkaline sphingomyelinase inhibits proliferation without inducing apoptosis in HT-29 colon carcinoma cells.
Journal of cancer research and clinical oncology 2003;129(10):577-82.
2003: David Andersson; Jian-Jun Liu; Ake Nilsson; Rui-Dong Duan
Ursolic acid inhibits proliferation and stimulates apoptosis in HT29 cells following activation of alkaline sphingomyelinase.
Anticancer research 2003;23(4):3317-22.
2003: Eva Hertervig; Ake Nilsson; Mef Nilbert; Rui-Dong Duan
Reduction in alkaline sphingomyelinase in colorectal tumorigenesis is not related to the APC gene mutation.
International journal of colorectal disease 2003;18(4):309-13.
2003: Rui-Dong Duan; Yajun Cheng; Gert Hansen; Eva Hertervig; Jian-Jun Liu; Ingvar Syk; Hans Sjostrom; Ake Nilsson
Purification, localization, and expression of human intestinal alkaline sphingomyelinase.
Journal of lipid research 2003;44(6):1241-50.
2003: Jan Lillienau; Yajun Cheng; Ake Nilsson; Rui-Dong Duan
Development of intestinal alkaline sphingomyelinase in rat fetus and newborn rat.
Lipids 2003;38(5):545-9.
2002: Jian-Jun Liu; Ake Nilsson; Stina Oredsson; Vladimir Badmaev; Wan-Zhou Zhao; Rui-Dong Duan
Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells.
Carcinogenesis 2002;23(12):2087-93.
2002: Jian-Jun Liu; Ake Nilsson; Stina Oredsson; Vladimir Badmaev; Rui-Dong Duan
Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway.
International journal of molecular medicine 2002;10(4):501-5.
2002: Liping Yang; Marja Mutanen; Yajun Cheng; Rui-Dong Duan
Effects of fat, beef and fiber in diets on activities of sphingomyelinase, ceramidase and caspase-3 in rat colonic mucosa.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2002;11(3):150-6.
2002: Urban Sjöqvist; Eva Hertervig; Ake Nilsson; Rui-Dong Duan; Ake Ost; Bernhard Tribukait; Robert Löfberg
Chronic colitis is associated with a reduction of mucosal alkaline sphingomyelinase activity.
Inflammatory bowel diseases 2002;8(4):258-63.
2002: Jian-Jun Liu; Ake Nilsson; Rui-Dong Duan
In vitro effects of fat, FA, and cholesterol on sphingomyelin hydrolysis induced by rat intestinal alkaline sphingomyelinase.
Lipids 2002;37(5):469-74.
2002: Jian-Jun Liu; Ji-Yao Wang; Chi Zhang; Ake Nilsson; Rui-Dong Duan
Hepatic cirrhosis increases sensitivity of kidney to endotoxin in rats.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(2):BR56-60.
2002: Yajun Cheng; Ake Nilsson; Elisabeth Tömquist; Rui-Dong Duan
Purification, characterization, and expression of rat intestinal alkaline sphingomyelinase.
Journal of lipid research 2002;43(2):316-24.
2002: Jian-Jun Liu; Ji-Yao Wang; Eva Hertervig; Ake Nilsson; Rui-Dong Duan
Sulindac induces apoptosis, inhibits proliferation and activates caspase-3 in Hep G2 cells.
Anticancer research 2002;22(1A):263-6.
2001: Rui-Dong Duan; Yajun Cheng; L Yang; Lena Ohlsson; Ake Nilsson
Evidence for specific ceramidase present in the intestinal contents of rats and humans.
Lipids 2001;36(8):807-12.
2001: P Lundgren; Ake Nilsson; Rui-Dong Duan
Distribution and properties of neutral ceramidase activity in rat intestinal tract.
Digestive diseases and sciences 2001;46(4):765-72.
2000: J J Liu; J Y Wang; Eva Hertervig; Y Cheng; A Nilsson; Rui-Dong Duan
Activation of neutral sphingomyelinase participates in ethanol-induced apoptosis in Hep G2 cells.
Alcohol and alcoholism (Oxford, Oxfordshire) 2000;35(6):569-73.
2000: Anne-Maria Pajari; Seija I Oikarinen; Rui-Dong Duan; Marja Mutanen
A high-beef diet alters protein kinase C isozyme expression in rat colonic mucosa.
The Journal of nutritional biochemistry 2000;11(10):474-81.
2000: L Nyberg; Rui-Dong Duan; A Nilsson
A mutual inhibitory effect on absorption of sphingomyelin and cholesterol.
The Journal of nutritional biochemistry 2000;11(5):244-9.
2000: J J Liu; A Nilsson; Rui-Dong Duan
Effects of phospholipids on sphingomyelin hydrolysis induced by intestinal alkaline sphingomyelinase: an in vitro study.
The Journal of nutritional biochemistry 2000;11(4):192-7.
2000: Rui-Dong Duan; Ake Nilsson
Sphingolipid hydrolyzing enzymes in the gastrointestinal tract.
Methods in enzymology 2000;311():276-86.
1999: Ake Nilsson; Rui-Dong Duan
Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract.
Chemistry and physics of lipids 1999;102(1-2):97-105.
1999: Yajun Cheng; Horst-Dietmar Tauschel; Ake Nilsson; Rui-Dong Duan
Ursodeoxycholic acid increases the activities of alkaline sphingomyelinase and caspase-3 in the rat colon.
Scandinavian journal of gastroenterology 1999;34(9):915-20.
1999: Eva Hertervig; Ake Nilsson; J Björk; R Hultkrantz; Rui-Dong Duan
Familial adenomatous polyposis is associated with a marked decrease in alkaline sphingomyelinase activity: a key factor to the unrestrained cell proliferation?
British journal of cancer 1999;81(2):232-6.
1998: L Nyberg; A Farooqi; Lars Bläckberg; Rui-Dong Duan; A Nilsson; Olle Hernell
Digestion of ceramide by human milk bile salt-stimulated lipase.
Journal of pediatric gastroenterology and nutrition 1998;27(5):560-7.
1998: Rui-Dong Duan
Sphingomyelin hydrolysis in the gut and clinical implications in colorectal tumorigenesis and other gastrointestinal diseases.
Scandinavian journal of gastroenterology 1998;33(7):673-83.
1998: Anne-Maria Pajari; P Häkkänen; Rui-Dong Duan; Marja Mutanen
Role of red meat and arachidonic acid in protein kinase C activation in rat colonic mucosa.
Nutrition and cancer 1998;32(2):86-94.
1998: Rui-Dong Duan; Yajun Cheng; Horst-Dietmar Tauschel; Ake Nilsson
Effects of ursodeoxycholate and other bile salts on levels of rat intestinal alkaline sphingomyelinase: a potential implication in tumorigenesis.
Digestive diseases and sciences 1998;43(1):26-32.
1997: Rui-Dong Duan; Ake Nilsson
Purification of a newly identified alkaline sphingomyelinase in human bile and effects of bile salts and phosphatidylcholine on enzyme activity.
Hepatology (Baltimore, Md.) 1997;26(4):823-30.
1997: Eva Hertervig; Ake Nilsson; L Nyberg; Rui-Dong Duan
Alkaline sphingomyelinase activity is decreased in human colorectal carcinoma.
Cancer 1997;79(3):448-53.
1997: Lars Bläckberg; Rui-Dong Duan; B Sternby
Purification of carboxyl ester lipase (bile salt-stimulated lipase) from human milk and pancreas.
Methods in enzymology 1997;284():185-94.
1996: Rui-Dong Duan; Eva Hertervig; L Nyberg; T Hauge; B Sternby; J Lillienau; A Farooqi; Ake Nilsson
Distribution of alkaline sphingomyelinase activity in human beings and animals. Tissue and species differences.
Digestive diseases and sciences 1996;41(9):1801-6.
1996: L Nyberg; Rui-Dong Duan; J Axelson; A Nilsson
Identification of an alkaline sphingomyelinase activity in human bile.
Biochimica et biophysica acta 1996;1300(1):42-8.
1995: Rui-Dong Duan; L Nyberg; Ake Nilsson
Alkaline sphingomyelinase activity in rat gastrointestinal tract: distribution and characteristics.
Biochimica et biophysica acta 1995;1259(1):49-55.
1993: Rui-Dong Duan; B Sternby
Decrease in contents of pancreatic carboxyl ester lipase, phospholipase A2, and lingual lipase in rats with streptozotocin-induced diabetes.
Scandinavian journal of gastroenterology 1993;28(3):256-60.
1992: Rui-Dong Duan; Charlotte Erlanson-Albertsson
Evidence of a stimulatory effect of cyclic AMP on pancreatic lipase and colipase synthesis in rats.
Scandinavian journal of gastroenterology 1992;27(8):644-8.
1989: Rui-Dong Duan; Charlotte Erlanson-Albertsson
Pancreatic lipase and colipase activity increase in pancreatic acinar tissue of diabetic rats.
Pancreas 1989;4(3):329-34.
1988: Rui-Dong Duan; Charlotte Erlanson-Albertsson
Calcium fluxes caused by bile salts in rat pancreatic acini.
Scandinavian journal of gastroenterology 1988;23(7):891-6.
1987: Charlotte Erlanson-Albertsson; A Larsson; Rui-Dong Duan
Secretion of pancreatic lipase and colipase from rat pancreas.
Pancreas 1987;2(5):531-5.