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Andrea Sapone

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Simone Melega; Eleonora Pagnotta; Donatella Canistro; Renato Iori; Andrea Sapone; Moreno Paolini
Effect of sprout extract from Tuscan black cabbage on xenobiotic-metabolizing and antioxidant enzymes in rat liver.
Donatella Canistro; Renato Iori; Simone Melega; Andrea Sapone; Ester Speroni; Jessica Barillari; Moreno Paolini
Black cabbage seed extract affects rat Cyp-mediated biotransformation: organ and sex related differences.
Andrea Sapone; Fabio Vivarelli; Donatella Canistro; Simone Melega; Ramona Moles; Moreno Paolini
On enzyme-based anticancer molecular dietary manipulations.

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All Publications

2013: Simone Melega; Eleonora Pagnotta; Donatella Canistro; Renato Iori; Andrea Sapone; Moreno Paolini
Effect of sprout extract from Tuscan black cabbage on xenobiotic-metabolizing and antioxidant enzymes in rat liver.
Mutation research 2013;751(1):45-51.
2012: Donatella Canistro; Renato Iori; Simone Melega; Andrea Sapone; Ester Speroni; Jessica Barillari; Moreno Paolini
Black cabbage seed extract affects rat Cyp-mediated biotransformation: organ and sex related differences.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(8):2612-21.
2012: Andrea Sapone; Fabio Vivarelli; Donatella Canistro; Simone Melega; Ramona Moles; Moreno Paolini
On enzyme-based anticancer molecular dietary manipulations.
Journal of biomedicine & biotechnology 2012;2012():790987.
2011: Jukka Puoliväli; Raimo Pussinen; Francesca Riccardino; Andrea Sapone; Antonio Soleti; Enzo Spisni; Leena Tähtivaara; Nina Vartiainen; Juha Yrjänheikki; Donatella Canistro; Taneli Heikkinen; Giedrius Kalesnykas; Kimmo Lehtimäki; Taina-Kaisa Miettinen; Antti Nurmi; Moreno Paolini
The radical scavenger IAC (bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) decantionate) decreases mortality, enhances cognitive functions in water maze and reduces amyloid plaque burden in hAβPP transgenic mice.
Journal of Alzheimer's disease : JAD 2011;27(3):499-510.
2010: Donatella Canistro; Alessandra A Affatato; Antonio Soleti; Vincenzo Mollace; Carolina Muscoli; Francesca Sculco; Iolanda Sacco; Valeria Visalli; Barbara Bonamassa; Manuela Martano; Michelangelo Iannone; Andrea Sapone; Moreno Paolini
The novel radical scavenger IAC is effective in preventing and protecting against post-ischemic brain damage in Mongolian gerbils.
Journal of the neurological sciences 2010;290(1-2):90-5.
2009: Donatella Canistro; Barbara Bonamassa; Laura Pozzetti; Andrea Sapone; S Z Abdel-Rahman; Gian Luigi Biagi; Moreno Paolini
Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(2):454-61.
2008: Donatella Canistro; Laura Pozzetti; Andrea Sapone; Massimiliano Broccoli; Alessandra Affatato; A Stradiotti; V Longo; Paola Menichini; R Barale; Moreno Paolini
Perturbation of murine liver cyp-superfamily of isoforms by different combinations of pesticide mixtures.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(1):34-42.
2008: Donatella Canistro; Laura Pozzetti; Andrea Sapone; Massimiliano Broccoli; Barbara Bonamassa; V Longo; V Lubrano; Jessica Barillari; Gian Luigi Biagi; Moreno Paolini
Perturbation of rat hepatic metabolising enzymes by folic acid supplementation.
Mutation research 2008;637(1-2):16-22.
2007: Andrea Sapone; Barbara Bonamassa; Donatella Canistro; Laura Pozzetti; Moreno Paolini
High-dose vitamin A.
Lancet 2007;370(9589):740.
2007: Jessica Barillari; Renato Iori; Massimiliano Broccoli; Laura Pozzetti; Donatella Canistro; Andrea Sapone; Barbara Bonamassa; Gian Luigi Biagi; Moreno Paolini
Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of brassicaceae, differently affect metabolizing enzymes in rats.
Journal of agricultural and food chemistry 2007;55(14):5505-11.
2007: Andrea Sapone; Alessandra Affatato; Donatella Canistro; Laura Pozzetti; Massimiliano Broccoli; Jessica Barillari; Renato Iori; Moreno Paolini
Cruciferous vegetables and lung cancer.
Mutation research 2007;635(2-3):146-8.
2007: Andrea Sapone; Bianca Gustavino; Monica Monfrinotti; Donatella Canistro; Massimiliano Broccoli; Laura Pozzetti; Alessandra Affatato; Luca Valgimigli; Giorgio Cantelli Forti; Gian Franco Pedulli; Gian Luigi Biagi; Sherif Z Abdel-Rahman; Moreno Paolini
Perturbation of cytochrome P450, generation of oxidative stress and induction of DNA damage in Cyprinus carpio exposed in situ to potable surface water.
Mutation research 2007;626(1-2):143-54.
2006: Paolo Perocco; Gabriele Bronzetti; Donatella Canistro; Luca Valgimigli; Andrea Sapone; Alessandra Affatato; Gian Franco Pedulli; Laura Pozzetti; Massimiliano Broccoli; Renato Iori; Jessica Barillari; Valeriana Sblendorio; Marvin S Legator; Moreno Paolini; Sherif Z Abdel-Rahman
Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver.
Mutation research 2006;595(1-2):125-36.
2005: Andrea Sapone; Donatella Canistro; Massimiliano Broccoli; Laura Pozzetti; Alessandra Affatato; Stefano Vangelisti; Gian Luigi Biagi; Valeriana Sblendorio; Moreno Paolini
Green tea and its isolated constituents in cancer prevention.
Mutation research 2005;578(1-2):434-5.
2005: A Filosa; Luca Valgimigli; G F Pedulli; Andrea Sapone; Aurelio Maggio; Disma Renda; C Scazzone; Roberto Malizia; Lorella Pitrolo; Carmela Lo Pinto; Zelia Borsellino; Liana Cuccia; Marcello Capra; Donatella Canistro; Massimiliano Broccoli; A Soleti; M Paolini
Quantitative evaluation of oxidative stress status on peripheral blood in beta-thalassaemic patients by means of electron paramagnetic resonance spectroscopy.
British journal of haematology 2005;131(1):135-40.
2005: Andrea Sapone; Laura Pozzetti; Donatella Canistro; Massimiliano Broccoli; Gabriele Bronzetti; Giuseppa Potenza; Alessandra Affatato; Gian Luigi Biagi; Giorgio Cantelli-Forti; Moreno Paolini
CYP superfamily perturbation by diflubenzuron or acephate in different tissues of CD1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2005;43(1):173-83.
2004: Moreno Paolini; Andrea Sapone; Frank J Gonzalez
Parkinson's disease, pesticides and individual vulnerability.
Trends in pharmacological sciences 2004;25(3):124-9.
2003: Moreno Paolini; Andrea Sapone; Donatella Canistro; Pasquale Chieco; Luca Valgimigli
Antioxidant vitamins for prevention of cardiovascular disease.
Lancet 2003;362(9387):920; author reply 921.
2003: Moreno Paolini; Andrea Sapone; Luca Valgimigli
Avoidance of bioflavonoid supplements during pregnancy: a pathway to infant leukemia?
Mutation research 2003;527(1-2):99-101.
2003: Andrea Sapone; Alessandra Affatato; Donatella Canistro; Massimiliano Broccoli; Silvia Trespidi; Laura Pozzetti; Gian Luigi Biagi; Giorgio Cantelli-Forti; Moreno Paolini
Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice.
Mutation research 2003;527(1-2):67-80.
2003: Moreno Paolini; Sherif Z Abdel-Rahman; Andrea Sapone; Gian Franco Pedulli; Paolo Perocco; Giorgio Cantelli-Forti; Marvin S Legator
Beta-carotene: a cancer chemopreventive agent or a co-carcinogen?
Mutation research 2003;543(3):195-200.
2003: Andrea Sapone; Dino Vaira; Silvia Trespidi; Federico Perna; Luigi Gatta; Andrea Tampieri; Chiara Ricci; Giorgio Cantelli-Forti; Mario Miglioli; Gian Luigi Biagi; Moreno Paolini
The clinical role of cytochrome p450 genotypes in Helicobacter pylori management.
The American journal of gastroenterology 2003;98(5):1010-5.
2003: Moreno Paolini; Andrea Sapone; Donatella Canistro; Maria Antonietta Antonelli; Pasquale Chieco
Diet and risk of cancer.
Lancet 2003;361(9353):257-8.
2002: Moreno Paolini; Andrea Sapone; Donatella Canistro; Pasquale Chieco; Carlo Bauer
Dietary effect on blood pressure.
Lancet 2002;360(9347):1786.
2002: Paolo Perocco; Renato Iori; Jessica Barillari; Massimiliano Broccoli; Andrea Sapone; Alessandra Affatato; Moreno Paolini
In vitro induction of benzo(a)pyrene cell-transforming activity by the glucosinolate gluconasturtiin found in cruciferous vegetables.
Cancer letters 2002;184(1):65-71.
2002: Andrea Sapone; Moreno Paolini; Gian Luigi Biagi; Giorgio Cantelli-Forti; Frank J Gonzalez
The pressing need for combined genotype-phenotype analysis in clinical practice.
Trends in pharmacological sciences 2002;23(6):260-1.
1998: Moreno Paolini; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Effect of licorice and glycyrrhizin on murine liver CYP-dependent monooxygenases.
Life sciences 1998;62(6):571-82.
1997: Moreno Paolini; Laura Pozzetti; Andrea Sapone; Gian Luigi Biagi; Giorgio Cantelli-Forti
Development of basal and induced testosterone hydroxylase activity in the chicken embryo in ovo.
British journal of pharmacology 1997;122(2):344-50.
1997: Moreno Paolini; Laura Pozzetti; Andrea Sapone; R Mesirca; Paolo Perocco; M Mazzullo; Giorgio Cantelli-Forti
Molecular non-genetic biomarkers of effect related to acephate cocarcinogenesis: sex- and tissue-dependent induction or suppression of murine CYPs.
Cancer letters 1997;117(1):7-15.
1997: Moreno Paolini; R Mesirca; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Biomarkers of effect in evaluating dithianon cocarcinogenesis: selective induction and suppression of murine CYP3A isoform.
Cancer letters 1997;113(1-2):221-8.
1996: Moreno Paolini; R Mesirca; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Biomarkers of effect in evaluating metalaxyl cocarcinogenesis. Selective induction of murine CYP 3A isoform.
Mutation research 1996;361(2-3):157-64.
1996: Moreno Paolini; R Mesirca; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Molecular non-genetic biomarkers related to Fenarimol cocarcinogenesis: organ- and sex-specific CYP induction in rat.
Cancer letters 1996;101(2):171-8.
1996: Milena Fini; Roberto Giardino; Romano Mongiorgi; Giorgio Cantelli-Forti; Saverio Gnudi; Nicolò Nicoli-Aldini; C Valdrè; D Piotti; Gianluca Giavaresi; L Orienti; Michele Rocca; Andrea Sapone; A Rossetti
[Experimental osteoporosis caused by estrogen deficiency in rats. Role of a lactose, L-arginine and L-lysine combination in the prevention and therapy].
Minerva medica 1996;87(3):81-8.
1996: Moreno Paolini; Laura Pozzetti; R Mesirca; Andrea Sapone; Giorgio Cantelli-Forti
Testosterone hydroxylase in evaluating induction and suppression of murine CYP isoenzymes by fenarimol.
Archives of toxicology 1996;70(7):451-6.
1996: Milena Fini; Roberto Giardino; Nicolò Nicoli-Aldini; L Martini; Michele Rocca; Franco Bertoni; S Capelli; Giorgio Cantelli-Forti; Andrea Sapone; A Rossetti; G Morrone; Gianluca Giavaresi
[Role of lactose, arginine and lysine combination in fracture healing (an experimental study)].
Annali italiani di chirurgia 1996;67(1):77-82; discussion 82-3.
1995: Moreno Paolini; R Mesirca; Laura Pozzetti; Andrea Sapone; Giorgio Cantelli-Forti
Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers.
Chemico-biological interactions 1995;95(1-2):127-39.
1992: Andrea Sapone; R Basaglia; Gian Luigi Biagi
[Drug-induced changes in the teeth and mouth. II].
La Clinica terapeutica 1992;140(6):575-83.
1992: Andrea Sapone; R Basaglia; Gian Luigi Biagi
[Odontostomatological changes induced by drugs. I].
La Clinica terapeutica 1992;140(5):487-98.
1991: Gian Luigi Biagi; M C Guerra; A M Barbaro; Andrea Sapone; M Recantini
Lipophilic character of cardiac glycosides: correlation between RM values and acute toxicity data in different animal species.
Journal of chromatography 1991;547(1-2):523-30.
1991: Gian Luigi Biagi; A M Barbaro; Maurizio Recanatini; Andrea Sapone; M C Guerra
[Lipophilic character and antibiotic action].
Giornale italiano di chemioterapia 1991;38(1-3):15-7.