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Gert Luurtsema

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Alie Schuitemaker; Thalia F van der Doef; Wiesje M van der Flier; Albert D Windhorst; Frederik Barkhof; Ronald Boellaard; Cees Jonker; Reina W Kloet; Dirk L Knol; Marc A Kropholler; Adriaan A Lammertsma; Gert Luurtsema; Philip scheltens; Bart N M Van Berckel
Microglial activation in Alzheimer's disease: an (R)-[¹¹C]PK11195 positron emission tomography study.
Marcel Benadiba; Carlos Alberto Buchpigel; Gert Luurtsema; Lauro Wichert-Ana; Geraldo Busatto Filho
New molecular targets for PET and SPECT imaging in neurodegenerative diseases.
Joost Verbeek; Albert D Windhorst; Elizabeth C de Lange; Jonas Eriksson; Gert Luurtsema; Robert Schuit; Stina Syvänen; Adriaan A Lammertsma
Synthesis and preclinical evaluation of [11C]D617, a metabolite of (R)-[11C]verapamil.

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All Publications

2013: Alie Schuitemaker; Thalia F van der Doef; Wiesje M van der Flier; Albert D Windhorst; Frederik Barkhof; Ronald Boellaard; Cees Jonker; Reina W Kloet; Dirk L Knol; Marc A Kropholler; Adriaan A Lammertsma; Gert Luurtsema; Philip scheltens; Bart N M Van Berckel
Microglial activation in Alzheimer's disease: an (R)-[¹¹C]PK11195 positron emission tomography study.
Neurobiology of aging 2013;34(1):128-36.
2012: Marcel Benadiba; Carlos Alberto Buchpigel; Gert Luurtsema; Lauro Wichert-Ana; Geraldo Busatto Filho
New molecular targets for PET and SPECT imaging in neurodegenerative diseases.
Revista brasileira de psiquiatria (São Paulo, Brazil : 1999) 2012;34 Suppl 2():S125-36.
2012: Joost Verbeek; Albert D Windhorst; Elizabeth C de Lange; Jonas Eriksson; Gert Luurtsema; Robert Schuit; Stina Syvänen; Adriaan A Lammertsma
Synthesis and preclinical evaluation of [11C]D617, a metabolite of (R)-[11C]verapamil.
Nuclear medicine and biology 2012;39(4):530-9.
2011: Saskia P Wolfensberger; Anu J Airaksinen; Ronald Boellaard; Frans E Janssens; Josée E Leysen; Mark Lubberink; Gert Luurtsema; Kaoru Maruyama; Wieb Reddingius; Bart N van Berckel; Dick J Veltman; Albert D Windhorst; Adriaan A Lammertsma
Quantification of the neurokinin 1 receptor ligand [¹¹C]R116301.
Nuclear medicine communications 2011;32(10):896-902.
2011: Onno L De Klerk; Johan A Den Boer; Rudi Dierckx; Gert Luurtsema; Ilja M Nolte; Fokko J Bosker; Heidrun Potschka
The role of p-glycoprotein in psychiatric disorders: a reliable guard of the brain?
Central nervous system agents in medicinal chemistry 2011;11(3):197-209.
2011: Jochem P Bremmer; L Jaap Kappelle; Catharina J M Klijn; Reina Kloet; Adriaan A Lammertsma; Gert Luurtsema; Suzanne Persoon; Abraham Rijbroek; Bart N M Van Berckel; Ronald Boellaard
Day-to-day test-retest variability of CBF, CMRO2, and OEF measurements using dynamic 15O PET studies.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2011;13(4):759-68.
2011: Stina Syvänen; Gert Luurtsema; Carla F M Molthoff; Albert D Windhorst; Marc C Huisman; Adriaan A Lammertsma; Rob A Voskuyl; Elizabeth C de Lange
(R)-[11C]verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus.
BMC medical imaging 2011;11():1.
2011: Mark Lubberink; Yeun Ying Wong; Pieter G H M Raijmakers; Robert Schuit; Gert Luurtsema; Ronald Boellaard; Paul Knaapen; Anton Vonk-Noordegraaf; Adriaan A Lammertsma
Myocardial oxygen extraction fraction measured using bolus inhalation of 15O-oxygen gas and dynamic PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(1):60-6.
2011: Ingrid Dijkgraaf; Cheng-Bin Yim; Gerben M Franssen; Robert Schuit; Gert Luurtsema; Shuang Liu; Wim J G Oyen; Otto C Boerman
PET imaging of αvβ₃ integrin expression in tumours with ⁶⁸Ga-labelled mono-, di- and tetrameric RGD peptides.
European journal of nuclear medicine and molecular imaging 2011;38(1):128-37.
2010: Gert Luurtsema; Ronald Boellaard; H N J M Greuter; Abraham Rijbroek; K Takkenkamp; F G M de Geest; Fred L Buijs; N Harry Hendrikse; E J F Franssen; A van Lingen; Adriaan A Lammertsma
Pharmaceutical preparation of oxygen-15 labelled molecular oxygen and carbon monoxide gasses in a hospital setting.
Journal of clinical pharmacy and therapeutics 2010;35(1):63-9.
2009: Nelleke Tolboom; Maqsood Yaqub; Ronald Boellaard; Gert Luurtsema; Albert D Windhorst; Philip scheltens; Adriaan A Lammertsma; Bart N M Van Berckel
Test-retest variability of quantitative [11C]PIB studies in Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2009;36(10):1629-38.
2009: Maqsood Yaqub; Ronald Boellaard; Bart N M Van Berckel; Nelleke Tolboom; Gert Luurtsema; Anke A Dijkstra; Mark Lubberink; Albert D Windhorst; Philip scheltens; Adriaan A Lammertsma
Evaluation of tracer kinetic models for analysis of [18F]FDDNP studies.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2009;11(5):322-33.
2009: Gert Luurtsema; Robert Schuit; Rob P Klok; Joost Verbeek; Josée E Leysen; Adriaan A Lammertsma; Albert D Windhorst
Evaluation of [11C]laniquidar as a tracer of P-glycoprotein: radiosynthesis and biodistribution in rats.
Nuclear medicine and biology 2009;36(6):643-9.
2009: Floris H P van Velden; Reina W Kloet; Bart N M Van Berckel; Fred L Buijs; Gert Luurtsema; Adriaan A Lammertsma; Ronald Boellaard
HRRT versus HR+ human brain PET studies: an interscanner test-retest study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(5):693-702.
2009: Nelleke Tolboom; Maqsood Yaqub; Wiesje M van der Flier; Ronald Boellaard; Gert Luurtsema; Albert D Windhorst; Frederik Barkhof; Philip scheltens; Adriaan A Lammertsma; Bart N M Van Berckel
Detection of Alzheimer pathology in vivo using both 11C-PIB and 18F-FDDNP PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(2):191-7.
2008: Gert Luurtsema; Robert Schuit; Kevin Takkenkamp; Mark Lubberink; N Harry Hendrikse; Albert D Windhorst; Carla F M Molthoff; Nelleke Tolboom; Bart N M Van Berckel; Adriaan A Lammertsma
Peripheral metabolism of [(18)F]FDDNP and cerebral uptake of its labelled metabolites.
Nuclear medicine and biology 2008;35(8):869-74.
2008: Bart N M Van Berckel; Matthijs Bossong; Ronald Boellaard; Reina Kloet; Alie Schuitemaker; Esther Caspers; Gert Luurtsema; Albert D Windhorst; Wiepke Cahn; Adriaan A Lammertsma; René S Kahn
Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography study.
Biological psychiatry 2008;64(9):820-2.
2008: N Harry Hendrikse; Gert Luurtsema; Astrid A M van der Veldt; Mark Lubberink
Positron emission tomography for modeling pathophysiological processes in vivo.
Current opinion in drug discovery & development 2008;11(5):717-25.
2008: Maqsood Yaqub; Nelleke Tolboom; Ronald Boellaard; Bart N M Van Berckel; Erica W van Tilburg; Gert Luurtsema; Philip scheltens; Adriaan A Lammertsma
Simplified parametric methods for [11C]PIB studies.
NeuroImage 2008;42(1):76-86.
2008: Astrid A M van der Veldt; Gert Luurtsema; Mark Lubberink; Adriaan A Lammertsma; N Harry Hendrikse
Individualized treatment planning in oncology: role of PET and radiolabelled anticancer drugs in predicting tumour resistance.
Current pharmaceutical design 2008;14(28):2914-31.
2008: Aiman Abrahim; Gert Luurtsema; Martin Bauer; Rudolf Karch; Mark Lubberink; Ekaterina Pataraia; Christian Joukhadar; Kurt Kletter; Adriaan A Lammertsma; Christoph Baumgartner; Markus Müller; Oliver Langer
Peripheral metabolism of (R)-[11C]verapamil in epilepsy patients.
European journal of nuclear medicine and molecular imaging 2008;35(1):116-23.
2007: Oliver Langer; Martin Bauer; Alexander Hammers; Rudolf Karch; Ekaterina Pataraia; Matthias Koepp; Aiman Abrahim; Gert Luurtsema; Martin Brunner; Raute Sunder-Plassmann; Fritz Zimprich; Christian Joukhadar; Stephan Gentzsch; Robert Dudczak; Kurt Kletter; Markus Müller; Christoph Baumgartner
Pharmacoresistance in epilepsy: a pilot PET study with the P-glycoprotein substrate R-[(11)C]verapamil.
Epilepsia 2007;48(9):1774-84.
2007: Mark Lubberink; Gert Luurtsema; Bart N M Van Berckel; Ronald Boellaard; Rolf Toornvliet; Albert D Windhorst; Eric J F Franssen; Adriaan A Lammertsma
Evaluation of tracer kinetic models for quantification of P-glycoprotein function using (R)-[11C]verapamil and PET.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(2):424-33.
2006: Eric J F Franssen; Gert Luurtsema; Adriaan A Lammertsma
Imaging P-glycoprotein at the human blood-brain barrier.
Clinical pharmacology and therapeutics 2006;80(3):302-3; author reply 303-4.
2006: Rolf Toornvliet; Bart N M Van Berckel; Gert Luurtsema; Mark Lubberink; Albert A Geldof; Tessa M Bosch; Ruud Oerlemans; Adriaan A Lammertsma; Eric J F Franssen
Effect of age on functional P-glycoprotein in the blood-brain barrier measured by use of (R)-[(11)C]verapamil and positron emission tomography.
Clinical pharmacology and therapeutics 2006;79(6):540-8.
2005: Ronald Boellaard; Paul Knaapen; Abraham Rijbroek; Gert Luurtsema; Adriaan A Lammertsma
Evaluation of basis function and linear least squares methods for generating parametric blood flow images using 15O-water and Positron Emission Tomography.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2005;7(4):273-85.
2005: Marc A Kropholler; Ronald Boellaard; Alie Schuitemaker; Bart N M Van Berckel; Gert Luurtsema; Albert D Windhorst; Adriaan A Lammertsma
Development of a tracer kinetic plasma input model for (R)-[11C]PK11195 brain studies.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(7):842-51.
2005: Henri N J M Greuter; Patricia L B van Ophemert; Gert Luurtsema; Bart N M Van Berckel; Eric J F Franssen; Bert D Windhorst; Adriaan A Lammertsma
Optimizing an online SPE-HPLC method for analysis of (R)-[11C]1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide [(R)-[11C]PK11195] and its metabolites in humans.
Nuclear medicine and biology 2005;32(3):307-12.
2005: Gert Luurtsema; Carla F M Molthoff; Robert Schuit; Albert D Windhorst; Adriaan A Lammertsma; Eric J F Franssen
Evaluation of (R)-[11C]verapamil as PET tracer of P-glycoprotein function in the blood-brain barrier: kinetics and metabolism in the rat.
Nuclear medicine and biology 2005;32(1):87-93.
2004: Gert Luurtsema; Elizabeth C M de Lange; Adriaan A Lammertsma; Eric J F Franssen
Transport across the blood-brain barrier: stereoselectivity and PET-tracers.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(5):306-18.
2004: Paul Knaapen; Ronald Boellaard; Marco J W Götte; Pieter A Dijkmans; Linda M C van Campen; Carel C de Cock; Gert Luurtsema; Cees A Visser; Adriaan A Lammertsma; Frans C Visser
Perfusable tissue index as a potential marker of fibrosis in patients with idiopathic dilated cardiomyopathy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(8):1299-304.
2004: Henri N J M Greuter; Patricia L B van Ophemert; Gert Luurtsema; Eric J F Franssen; Ronald Boellaard; Adriaan A Lammertsma
Validation of a multiwell gamma-counter for measuring high-pressure liquid chromatography metabolite profiles.
Journal of nuclear medicine technology 2004;32(1):28-32.
2003: Gert Luurtsema; Carla F M Molthoff; Albert D Windhorst; J W Smit; H Keizer; Ronald Boellaard; Adriaan A Lammertsma; Eric J F Franssen
(R)- and (S)-[11C]verapamil as PET-tracers for measuring P-glycoprotein function: in vitro and in vivo evaluation.
Nuclear medicine and biology 2003;30(7):747-51.