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Sigfrido Scarpa

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Andrea Fuso; Elisa Isopi; Franco Mangia; Vincenzina Nicolia; Laura Ricceri; Rosaria A Cavallaro; Maria Teresa Fiorenza; Sigfrido Scarpa
S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice.
Andrea Fuso; Vincenzina Nicolia; Rosaria A Cavallaroa; Rosaria A Cavallaro; Sigfrido Scarpa
PSEN1 promoter demethylation in hyperhomocysteinemic TgCRND8 mice is the culprit, not the consequence.
Andrea Fuso; Vincenzina Nicolia; Rosaria A Cavallaro; Sigfrido Scarpa
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.

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2012: Andrea Fuso; Elisa Isopi; Franco Mangia; Vincenzina Nicolia; Laura Ricceri; Rosaria A Cavallaro; Maria Teresa Fiorenza; Sigfrido Scarpa
S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice.
Neurobiology of aging 2012;33(7):1482.e1-16.
2012: Andrea Fuso; Vincenzina Nicolia; Rosaria A Cavallaroa; Rosaria A Cavallaro; Sigfrido Scarpa
PSEN1 promoter demethylation in hyperhomocysteinemic TgCRND8 mice is the culprit, not the consequence.
Current Alzheimer research 2012;9(5):527-35.
2011: Andrea Fuso; Vincenzina Nicolia; Rosaria A Cavallaro; Sigfrido Scarpa
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models.
The Journal of nutritional biochemistry 2011;22(3):242-51.
2011: Andrea Fuso; Vincenzina Nicolia; Alessia Pasqualato; Maria Teresa Fiorenza; Rosaria A Cavallaro; Sigfrido Scarpa
Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency.
Neurobiology of aging 2011;32(2):187-99.
2010: Marina Borro; Rosaria A Cavallaro; Giovanna Gentile; Vincenzina Nicolia; Andrea Fuso; Maurizio Simmaco; Sigfrido Scarpa
One-carbon metabolism alteration affects brain proteome profile in a mouse model of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;22(4):1257-68.
2010: Rosaria A Cavallaro; Andrea Fuso; Vincenzina Nicolia; Sigfrido Scarpa
S-adenosylmethionine prevents oxidative stress and modulates glutathione metabolism in TgCRND8 mice fed a B-vitamin deficient diet.
Journal of Alzheimer's disease : JAD 2010;20(4):997-1002.
2010: Vincenzina Nicolia; Andrea Fuso; Rosaria A Cavallaro; Andrea Di Luzio; Sigfrido Scarpa
B vitamin deficiency promotes tau phosphorylation through regulation of GSK3beta and PP2A.
Journal of Alzheimer's disease : JAD 2010;19(3):895-907.
2008: Andrea Fuso; Vincenzina Nicolia; Rosaria A Cavallaro; Laura Ricceri; Fabrizio D'Anselmi; Pierpaolo Coluccia; Gemma Calamandrei; Sigfrido Scarpa
B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice.
Molecular and cellular neurosciences 2008;37(4):731-46.
2008: Fabrizio D'Anselmi; Alessandra Cucina; Giuseppe Cavallaro; Mariano Bizzarri; Rosaria A Cavallaro; Andrea Fuso; Antonino Cavallaro; Sigfrido Scarpa
S-adenosylmethionine inhibits ubiquitin-proteasome system in vitro and on rat vascular smooth muscle cells.
Protein and peptide letters 2008;15(1):58-62.
2007: Andrea Fuso; Rosaria A Cavallaro; Alessandro Zampelli; Fabrizio D'Anselmi; Paola Piscopo; Annamaria Confaloni; Sigfrido Scarpa
gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells.
Journal of Alzheimer's disease : JAD 2007;11(3):275-90.
2006: Anna Riccioli; Donatella Starace; Roberta Galli; Andrea Fuso; Sigfrido Scarpa; Fioretta Palombi; Paola De Cesaris; Elio Ziparo; Antonio Filippini
Sertoli cells initiate testicular innate immune responses through TLR activation.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7122-30.
2006: Rosaria A Cavallaro; Andrea Fuso; Fabrizio D'Anselmi; Laura Seminara; Sigfrido Scarpa
The effect of S-adenosylmethionine on CNS gene expression studied by cDNA microarray analysis.
Journal of Alzheimer's disease : JAD 2006;9(4):415-9.
2006: Sigfrido Scarpa; Rosaria A Cavallaro; Fabrizio D'Anselmi; Andrea Fuso
Gene silencing through methylation: an epigenetic intervention on Alzheimer disease.
Journal of Alzheimer's disease : JAD 2006;9(4):407-14.
2006: Andrea Fuso; Sigfrido Scarpa; Francesco Grandoni; Roberto Strom; Marco Lucarelli
A reassessment of semiquantitative analytical procedures for DNA methylation: comparison of bisulfite- and HpaII polymerase-chain-reaction-based methods.
Analytical biochemistry 2006;350(1):24-31.
2005: Claudia Desiderio; Rosaria A Cavallaro; Antonella De Rossi; Fabrizio D'Anselmi; Andrea Fuso; Sigfrido Scarpa
Evaluation of chemical and diastereoisomeric stability of S-adenosylmethionine in aqueous solution by capillary electrophoresis.
Journal of pharmaceutical and biomedical analysis 2005;38(3):449-56.
2005: Andrea Fuso; Laura Seminara; Rosaria A Cavallaro; Fabrizio D'Anselmi; Sigfrido Scarpa
S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production.
Molecular and cellular neurosciences 2005;28(1):195-204.
2003: Sigfrido Scarpa; Andrea Fuso; Fabrizio D'Anselmi; Rosaria A Cavallaro
Presenilin 1 gene silencing by S-adenosylmethionine: a treatment for Alzheimer disease?
FEBS letters 2003;541(1-3):145-8.
2002: Marco Lucarelli; Valeria Borrelli; Anna Fiori; Alessandra Cucina; Filippo Granata; Rosa Luisa Potenza; Sigfrido Scarpa; Antonino Cavallaro; Roberto Strom
The expression of native and oxidized LDL receptors in brain microvessels is specifically enhanced by astrocytes-derived soluble factor(s).
FEBS letters 2002;522(1-3):19-23.
2002: Patrizia Cardelli; Sigfrido Scarpa; Fabrizio Ceci; Marco Lucarelli; Fabio Tabacco; Giampiero Ferraguti; Fabrizia Brisdelli; Roberto Strom; Argante Bozzi
Effects of different oxidizing agents on neutral amino acid transport systems in isolated bovine brain microvessels.
Neurochemistry international 2002;41(1):29-36.
2002: Alessandra Cucina; Valeria Borrelli; Marco Lucarelli; Antonio V Sterpetti; Antonino Cavallaro; Roberto Strom; Luciana Santoro-D'Angelo; Sigfrido Scarpa
Autocrine production of basic fibroblast growth factor translated from novel synthesized mRNA mediates thrombin-induced mitogenesis in smooth muscle cells.
Cell biochemistry and function 2002;20(1):39-46.
2001: Andrea Fuso; Rosaria A Cavallaro; L Orrù; F R Buttarelli; Sigfrido Scarpa
Gene silencing by S-adenosylmethionine in muscle differentiation.
FEBS letters 2001;508(3):337-40.
2001: Marco Lucarelli; Andrea Fuso; Roberto Strom; Sigfrido Scarpa
The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation.
The Journal of biological chemistry 2001;276(10):7500-6.
2001: Sigfrido Scarpa; Lorena Narzi; Marco Lucarelli; L Orrù; Roberto Strom
Erythroid differentiation and regulatory gene expression are modulated by adenosine derivatives interfering with S-adenosylmethionine metabolic pathway.
Journal of cellular biochemistry 2001;81(3):401-12.
1999: Alessandra Cucina; Valentina Corvino; Paolo Sapienza; Valeria Borrelli; Marco Lucarelli; Sigfrido Scarpa; Roberto Strom; Luciana Santoro-D'Angelo; Antonino Cavallaro
Nicotine regulates basic fibroblastic growth factor and transforming growth factor beta1 production in endothelial cells.
Biochemical and biophysical research communications 1999;257(2):306-12.
1998: S Minotti; bianca maria scicchitano; Clara Nervi; Sigfrido Scarpa; Marco Lucarelli; Mario Molinaro; Sergio Adamo
Vasopressin and insulin-like growth factors synergistically induce myogenesis in serum-free medium.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(2):155-63.
1997: Marco Lucarelli; Massimo Gennarelli; Patrizia Cardelli; Giuseppe Novelli; Sigfrido Scarpa; Bruno Dallapiccola; Roberto Strom
Expression of receptors for native and chemically modified low-density lipoproteins in brain microvessels.
FEBS letters 1997;401(1):53-8.
1996: Sigfrido Scarpa; Marco Lucarelli; Fabrizio Palitti; D Carotti; Roberto Strom
Simultaneous myogenin expression and overall DNA hypomethylation promote in vitro myoblast differentiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(8):1051-8.
1989: Sigfrido Scarpa; O Sapora; M A Tabocchini; L Di Renzo; M Bigioni; S Pazzaglia; Fabrizio Palitti; D Carotti; Roberto Strom
Effect of X-rays on the differentiation of L5 myoblast cell line.
The Italian journal of biochemistry 1989;38(4):263A-265A.
1986: Aharon Razin; M Szyf; Tal Kafri; M Roll; H Giloh; Sigfrido Scarpa; D Carotti; G L Cantoni
Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(9):2827-31.
1985: Sigfrido Scarpa; B W Uhlendorf; G L Cantoni
The differentiation of L5/A10 myoblast cell line (a subclone of L5 line) is controlled by changes of culture conditions.
Cell differentiation 1985;17(2):105-14.
1984: Sigfrido Scarpa; R Strom; A Bozzi; R R Aksamit; P S Backlund; J Chen; G L Cantoni
Differentiation of myoblast cell lines and biological methylation: 3-deazaadenosine stimulates formation of multinucleated myofibers.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(10):3064-8.