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Jürgen Sonnemann

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Jürgen Sonnemann; Susann Wittig; Sabine Becker; Bernd Gruhn; James F Beck
Increased activity of histone deacetylases in childhood acute lymphoblastic leukaemia and acute myeloid leukaemia: support for histone deacetylase inhibitors as antileukaemic agents.
Jürgen Sonnemann; Navina Trommer; Susan Wittig; Sabine Becker; Désirée Grauel; Chithra D Palani; James F Beck
Histone deacetylase inhibitor-mediated sensitization to TRAIL-induced apoptosis in childhood malignancies is not associated with upregulation of TRAIL receptor expression, but with potentiated caspase-8 activation.
Jürgen Sonnemann; Chithra D Palani; Susan Wittig; Sabine Becker; Friederike Eichhorn; Astrid Voigt; James F Beck
Anticancer effects of the p53 activator nutlin-3 in Ewing's sarcoma cells.

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All Publications

2012: Jürgen Sonnemann; Susann Wittig; Sabine Becker; Bernd Gruhn; James F Beck
Increased activity of histone deacetylases in childhood acute lymphoblastic leukaemia and acute myeloid leukaemia: support for histone deacetylase inhibitors as antileukaemic agents.
British journal of haematology 2012;158(5):664-6.
2012: Jürgen Sonnemann; Navina Trommer; Susan Wittig; Sabine Becker; Désirée Grauel; Chithra D Palani; James F Beck
Histone deacetylase inhibitor-mediated sensitization to TRAIL-induced apoptosis in childhood malignancies is not associated with upregulation of TRAIL receptor expression, but with potentiated caspase-8 activation.
Cancer biology & therapy 2012;13(6):417-24.
2011: Jürgen Sonnemann; Chithra D Palani; Susan Wittig; Sabine Becker; Friederike Eichhorn; Astrid Voigt; James F Beck
Anticancer effects of the p53 activator nutlin-3 in Ewing's sarcoma cells.
European journal of cancer (Oxford, England : 1990) 2011;47(9):1432-41.
2011: Ina Kurtze; Jürgen Sonnemann; James F Beck
KRAS-mutated non-small cell lung cancer cells are responsive to either co-treatment with erlotinib or gefitinib and histone deacetylase inhibitors or single treatment with lapatinib.
Oncology reports 2011;25(4):1021-9.
2010: Gabriele Wolf; Nicole Aumann; Marta Michalska; Antje Bast; Jürgen Sonnemann; James F Beck; Uwe Lendeckel; Philip Newsholme; Reinhard Walther
Peroxiredoxin III protects pancreatic ß cells from apoptosis.
The Journal of endocrinology 2010;207(2):163-75.
2010: Mareike Schmudde; Erika Friebe; Jürgen Sonnemann; James F Beck; Barbara M Bröker
Histone deacetylase inhibitors prevent activation of tumour-reactive NK cells and T cells but do not interfere with their cytolytic effector functions.
Cancer letters 2010;295(2):173-81.
2010: Jürgen Sonnemann; Chithra D Palani; Lénia Ferrão Beck; Bettina Appel; James F Beck
Serine proteases in histone deacetylase inhibitor-induced apoptosis.
Molecular cancer therapeutics 2010;9(8):2440-1; author reply 2441-2.
2010: Jürgen Sonnemann; Stephanie Gressmann; Sabine Becker; Susan Wittig; Mareike Schmudde; James F Beck
The histone deacetylase inhibitor vorinostat induces calreticulin exposure in childhood brain tumour cells in vitro.
Cancer chemotherapy and pharmacology 2010;66(3):611-6.
2008: Mareike Schmudde; André Braun; Daniela Pende; Jürgen Sonnemann; Ulrike Klier; James F Beck; Lorenzo Moretta; Barbara M Bröker
Histone deacetylase inhibitors sensitize tumour cells for cytotoxic effects of natural killer cells.
Cancer letters 2008;272(1):110-21.
2008: Johanna Dzieran; James F Beck; Jürgen Sonnemann
Differential responsiveness of human hepatoma cells versus normal hepatocytes to TRAIL in combination with either histone deacetylase inhibitors or conventional cytostatics.
Cancer science 2008;99(8):1685-92.
2008: Jürgen Sonnemann; Isabel Hüls; Michael Sigler; Chithra D Palani; Le Thi Thu Hong; Uwe Völker; Heyo K Kroemer; James F Beck
Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells.
Oncology reports 2008;20(1):219-24.
2007: Jürgen Sonnemann; Beata Bumbul; James F Beck
Synergistic activity of the histone deacetylase inhibitor suberoylanilide hydroxamic acid and the bisphosphonate zoledronic acid against prostate cancer cells in vitro.
Molecular cancer therapeutics 2007;6(11):2976-84.
2007: Jürgen Sonnemann; Linn Dreyer; Maite Hartwig; Chithra D Palani; Le Thi Thu Hong; Ulrike Klier; Barbara M Bröker; Uwe Völker; James F Beck
Histone deacetylase inhibitors induce cell death and enhance the apoptosis-inducing activity of TRAIL in Ewing's sarcoma cells.
Journal of cancer research and clinical oncology 2007;133(11):847-58.
2007: Janka Reimer; Sandra Bien; Jürgen Sonnemann; James F Beck; Thomas Wieland; Heyo K Kroemer; Christoph A Ritter
Reduced expression of Rho guanine nucleotide dissociation inhibitor-alpha modulates the cytotoxic effect of busulfan in HEK293 cells.
Anti-cancer drugs 2007;18(3):333-40.
2007: Matthias Felber; Jürgen Sonnemann; James F Beck
Inhibition of novel protein kinase C-epsilon augments TRAIL-induced cell death in A549 lung cancer cells.
Pathology oncology research : POR 2007;13(4):295-301.
2007: K Saravana Kumar; Jürgen Sonnemann; Le Thi Thu Hong; Cornelis Buurman; Frank Adler; Manfred Maass; Uwe Völker; James F Beck
Histone deacetylase inhibitors, but not vincristine, cooperate with radiotherapy to induce cell death in medulloblastoma.
Anticancer research 2007;27(1A):465-70.
2006: K Saravana Kumar; Jürgen Sonnemann; James F Beck
Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells.
Oncology reports 2006;16(5):1047-52.
2006: Jürgen Sonnemann; K Saravana Kumar; Sandra Heesch; Cornelia Müller; Christoph Hartwig; Manfred Maass; Peter Bader; James F Beck
Histone deacetylase inhibitors induce cell death and enhance the susceptibility to ionizing radiation, etoposide, and TRAIL in medulloblastoma cells.
International journal of oncology 2006;28(3):755-66.
2006: Jürgen Sonnemann; Maite Hartwig; Andrea Plath; K Saravana Kumar; Cornelia Müller; James F Beck
Histone deacetylase inhibitors require caspase activity to induce apoptosis in lung and prostate carcinoma cells.
Cancer letters 2006;232(2):148-60.
2006: Jürgen Sonnemann; Jennifer Gänge; Sabine Pilz; Christine Stötzer; Ralf Ohlinger; Antje Belau; Gerd Lorenz; James F Beck
Comparative evaluation of the treatment efficacy of suberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer cell lines and primary ovarian cancer cells from patients.
BMC cancer 2006;6():183.
2005: Jürgen Sonnemann; Jennifer Gänge; K Saravana Kumar; Cornelia Müller; Peter Bader; James F Beck
Histone deacetylase inhibitors interact synergistically with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis in carcinoma cell lines.
Investigational new drugs 2005;23(2):99-109.
2004: Jürgen Sonnemann; Volker Gekeler; Antje Sagrauske; Cornelia Müller; Hans-Peter Hofmann; James F Beck
Apoptotic responsiveness of PC-3 prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand: evidence for differential effects of Bcl-xL and Bcl-2 down-regulation.
International journal of oncology 2004;25(4):1171-81.
2004: Jürgen Sonnemann; Volker Gekeler; Antje Sagrauske; Cornelia Müller; Hans-Peter Hofmann; James F Beck
Down-regulation of protein kinase Ceta potentiates the cytotoxic effects of exogenous tumor necrosis factor-related apoptosis-inducing ligand in PC-3 prostate cancer cells.
Molecular cancer therapeutics 2004;3(7):773-81.
2004: Jürgen Sonnemann; Volker Gekeler; Katrin Ahlbrecht; Klaus Brischwein; Chao Liu; Peter Bader; Cornelia Müller; Dietrich Niethammer; James F Beck
Down-regulation of protein kinase Ceta by antisense oligonucleotides sensitises A549 lung cancer cells to vincristine and paclitaxel.
Cancer letters 2004;209(2):177-85.
2004: Sandra Bien; Christoph A Ritter; Matthias Gratz; Bernhard Sperker; Jürgen Sonnemann; James F Beck; Heyo K Kroemer
Nuclear factor-kappaB mediates up-regulation of cathepsin B by doxorubicin in tumor cells.
Molecular pharmacology 2004;65(5):1092-102.
2004: Christina Schlatterer; Kathrin Happle; Daniel F Lusche; Jürgen Sonnemann
Cytosolic [Ca2+] transients in dictyostelium discoideum depend on the filling state of internal stores and on an active sarco/endoplasmic reticulum calcium ATPase (SERCA) Ca2+ pump.
The Journal of biological chemistry 2004;279(18):18407-14.
2003: Jürgen Sonnemann; Vera Eckervogt; Borna Truckenbrod; Joachim Boos; Winfried Winkelmann; Frans van Valen
The bisphosphonate pamidronate is a potent inhibitor of Ewing's sarcoma cell growth in vitro.
Anti-cancer drugs 2003;14(9):767-71.
2001: Jürgen Sonnemann; Vera Eckervogt; Borna Truckenbrod; Joachim Boos; Winfried Winkelmann; Frans van Valen
The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro.
Anti-cancer drugs 2001;12(5):459-65.
2000: Frans van Valen; Simone Fulda; Borna Truckenbrod; Vera Eckervogt; Jürgen Sonnemann; Axel Hillmann; Robert Rödl; Christiane Hoffmann; Winfried Winkelmann; L Schäfer; Barbara Dockhorn-Dworniczak; T Wessel; Joachim Boos; Klaus-Michael Debatin; Heribert Jürgens
Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL).
International journal of cancer. Journal international du cancer 2000;88(2):252-9.
1998: Jürgen Sonnemann; A Aichem; Christina Schlatterer
Dissection of the cAMP induced cytosolic calcium response in Dictyostelium discoideum: the role of cAMP receptor subtypes and G protein subunits.
FEBS letters 1998;436(2):271-6.
1998: Ralph H Schaloske; Jürgen Sonnemann; Dieter Malchow; Christina Schlatterer
Fatty acids induce release of Ca2+ from acidosomal stores and activate capacitative Ca2+ entry in Dictyostelium discoideum.
The Biochemical journal 1998;332 ( Pt 2)():541-8.
1997: Jürgen Sonnemann; G Knoll; Christina Schlatterer
cAMP-induced changes in the cytosolic free Ca2+ concentration in Dictyostelium discoideum are light sensitive.
Cell calcium 1997;22(1):65-74.
1995: Jürgen Sonnemann; Rupert Mutzel
Cytosolic nucleoside diphosphate kinase associated with the translation apparatus may provide GTP for protein synthesis.
Biochemical and biophysical research communications 1995;209(2):490-6.
1993: Jürgen Sonnemann; G Drugeon; A L Haenni; Rupert Mutzel
Elongation in a Dictyostelium in vitro translation system is affected by calmodulin antagonists.
FEBS letters 1993;329(1-2):183-8.
1991: Jürgen Sonnemann; A Bäuerle; T Winckler; Rupert Mutzel
A ribosomal calmodulin-binding protein from Dictyostelium.
The Journal of biological chemistry 1991;266(34):23091-6.