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Pierre Brissot

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Gérard Lescoat; Olivier Loréal; Olive Lowe; Isabelle Morel; Martine Ropert; Pierre Brissot; Isabelle Cannie; Lucie Gouffier; Sylvie Lepage; François Gaboriau
Involvement of polyamines in iron(III) transport in human intestinal Caco-2 cell lines.
Edouard Bardou-Jacquet; Pierre Brissot; Anne Guillygomarc'h; Dominique Guyader; Marianne Latournerie; Caroline Le Lan; Ludivine Legros; Draman Soro; Romain Moirand
Effect of alcohol consumption on liver stiffness measured by transient elastography.
Timothée Wallenhorst; Edouard Bardou-Jacquet; Andréa Manunta; Jean-Yves Poirier; Nathalie Rioux-Leclerc; Pierre Brissot
Chronic hepatic cytolysis revealing a pheochromocytoma.

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2013: Gérard Lescoat; Olivier Loréal; Olive Lowe; Isabelle Morel; Martine Ropert; Pierre Brissot; Isabelle Cannie; Lucie Gouffier; Sylvie Lepage; François Gaboriau
Involvement of polyamines in iron(III) transport in human intestinal Caco-2 cell lines.
Molecular and cellular biochemistry 2013;378(1-2):205-15.
2013: Edouard Bardou-Jacquet; Pierre Brissot; Anne Guillygomarc'h; Dominique Guyader; Marianne Latournerie; Caroline Le Lan; Ludivine Legros; Draman Soro; Romain Moirand
Effect of alcohol consumption on liver stiffness measured by transient elastography.
World journal of gastroenterology : WJG 2013;19(4):516-22.
2012: Timothée Wallenhorst; Edouard Bardou-Jacquet; Andréa Manunta; Jean-Yves Poirier; Nathalie Rioux-Leclerc; Pierre Brissot
Chronic hepatic cytolysis revealing a pheochromocytoma.
Clinics and research in hepatology and gastroenterology 2012;36(4):e60-2.
2012: Valerio Saglini; Pierre Brissot
[Hyperferritinemia--Algorithm].
Revue médicale suisse 2012;8(342):1135-7.
2012: Pierre Brissot; Caroline Le Lan; Martine Ropert; Olivier Loréal
Non-transferrin bound iron: a key role in iron overload and iron toxicity.
Biochimica et biophysica acta 2012;1820(3):403-10.
2012: Caroline Le Lan; Claude Védeilhié; Pierre Brissot; Hélène Danielou; Yves Deugnier; Anne Guillygomarc'h; Dominique Guyader; Fabrice Lainé; Gérard Le Dréau; Romain Moirand
A multi-disciplinary approach to treating hepatitis C with interferon and ribavirin in alcohol-dependent patients with ongoing abuse.
Journal of hepatology 2012;56(2):334-40.
2011: Edouard Bardou-Jacquet; Eolia Brissot; Pierre Brissot; Lénaïck Détivaud; Nadia Fatih; Marie-Laure Island; Anne-Marie Jouanolle; Hervé Maisonneuve; Annick Mosser; Martine Ropert; Olivier Loréal
A novel N491S mutation in the human SLC11A2 gene impairs protein trafficking and in association with the G212V mutation leads to microcytic anemia and liver iron overload.
Blood cells, molecules & diseases 2011;47(4):243-8.
2011: Pierre Brissot; Anne-Marie Jouanolle; Edouard Bardou-Jacquet; Olivier Loréal
Iron disorders of genetic origin: a changing world.
Trends in molecular medicine 2011;17(12):707-13.
2011: Pascal Guggenbuhl; Pierre Brissot; Olivier Loréal
Miscellaneous non-inflammatory musculoskeletal conditions. Haemochromatosis: the bone and the joint.
Best practice & research. Clinical rheumatology 2011;25(5):649-64.
2011: Yves Deugnier; Vanessa Giannone; Louis Griffel; John B Porter; Martine Ropert; Bruno Turlin; Yiyun Zhang; M Domenica Cappellini; Pierre Brissot
Improvement in liver pathology of patients with β-thalassemia treated with deferasirox for at least 3 years.
Gastroenterology 2011;141(4):1202-11, 1211.e1-3.
2011: Alain Gautier; Fabrice Lainé; Catherine Massart; Xavier Piguel; Laure Sandret; Beverley Balkau; Pierre Brissot; Yves Deugnier; Fabrice Bonnet
Liver iron overload is associated with elevated SHBG concentration and moderate hypogonadotrophic hypogonadism in dysmetabolic men without genetic haemochromatosis.
European journal of endocrinology / European Federation of Endocrine Societies 2011;165(2):339-43.
2011: Marie-Laure Island; Patricia Leroyer; Pierre Brissot; Nadia Fatih; Olivier Loreal
GATA-4 transcription factor regulates hepatic hepcidin expression.
The Biochemical journal 2011;437(3):477-82.
2011: Pierre Brissot; Helena Cannon; Simon Ball; Diana Rofail; Vivian Wu Jin
Hereditary hemochromatosis: patient experiences of the disease and phlebotomy treatment.
Transfusion 2011;51(6):1331-8.
2011: Caroline Le Lan; Annick Mosser; Martine Ropert; Lénaïck Detivaud; Véronique Loustaud-Ratti; Denis Vital-Durand; Laurent Roget; Edouard Bardou-Jacquet; Bruno Turlin; Véronique David; Olivier Loréal; Yves Deugnier; Pierre Brissot; Anne-Marie Jouanolle
Sex and acquired cofactors determine phenotypes of ferroportin disease.
Gastroenterology 2011;140(4):1199-1207.e1-2.
2011: Thi Hong Tuoi Do; Olivier Loréal; Romain Moirand; Martine Ropert; Pierre Brissot; Isabelle Cannie; François Gaboriau; Gérard Lescoat
Ethanol effect on cell proliferation in the human hepatoma HepaRG cell line: relationship with iron metabolism.
Alcoholism, clinical and experimental research 2011;35(3):408-19.
2010: Pradyumna Phatak; Pierre Brissot; Mark Wurster; Paul C Adams; Herbert L Bonkovsky; John Gross; Peter Malfertheiner; Gordon D McLaren; Claus Niederau; Alberto Piperno; Lawrie W Powell; Mark W Russo; Ulrich Stoelzel; Wolfgang Stremmel; Louis Griffel; Nicola Lynch; Yiyun Zhang; Antonello Pietrangelo
A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis.
Hepatology (Baltimore, Md.) 2010;52(5):1671-779.
2010: Pierre Brissot; Edouard Bardou-Jacquet; Marie-Bérengère Troadec; Annick Mosser; Marie-Laure Island; Lénaïck Detivaud; Olivier Loréal; Anne-Marie Jouanolle
Molecular diagnosis of genetic iron-overload disorders.
Expert review of molecular diagnostics 2010;10(6):755-63.
2010: Eric HITTI; Pierre-Antoine Eliat; Emmanuelle Abgueguen; Martine Ropert; Patricia Leroyer; Pierre Brissot; Yves Gandon; Herve Saint-Jalmes; Olivier Loréal
MRI quantification of splenic iron concentration in mouse.
Journal of magnetic resonance imaging : JMRI 2010;32(3):639-46.
2010: Nadia Fatih; Emilie Camberlein; Marie Laure Island; Anne Corlu; Emmanuelle Abgueguen; Lénaïck Détivaud; Patricia Leroyer; Pierre Brissot; Olivier Loréal
Natural and synthetic STAT3 inhibitors reduce hepcidin expression in differentiated mouse hepatocytes expressing the active phosphorylated STAT3 form.
Journal of molecular medicine (Berlin, Germany) 2010;88(5):477-86.
2010: François Gaboriau; Anne-Marie Leray; Martine Ropert; Lucie Gouffier; Isabelle Cannie; Marie-Bérengère Troadec; Olivier Loréal; Pierre Brissot; Gérard Lescoat
Effects of deferasirox and deferiprone on cellular iron load in the human hepatoma cell line HepaRG.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2010;23(2):231-45.
2010: Emilie Camberlein; Emmanuelle Abgueguen; Nadia Fatih; François Canonne-Hergaux; Patricia Leroyer; Bruno Turlin; Martine Ropert; Pierre Brissot; Olivier Loréal
Hepcidin induction limits mobilisation of splenic iron in a mouse model of secondary iron overload.
Biochimica et biophysica acta 2010;1802(3):339-46.
2009: Mathieu Revest; A Perlat; Olivier Decaux; Thierry Lamy; Marc Vérin; Pierre Brissot; Bernard Grosbois
[Gaucher's disease in Rennes University hospital: a 10-year retrospective study].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 2009;30(10):847-56.
2009: Dorothée Videt-Gibou; Serge Belliard; Edouard Bardou-Jacquet; Marie-Bérengère Troadec; Caroline Le Lan; Anne-Marie Jouanolle; Olivier Loréal; Joseph Rivalan; Pierre Brissot
Iron excess treatable by copper supplementation in acquired aceruloplasminemia: a new form of secondary human iron overload?
Blood 2009;114(11):2360-1.
2009: Marie-Laure Anne; Caroline Le Lan; Valérie Monbet; Catherine Boussard-Plédel; Martine Ropert; Olivier Sire; Michel Pouchard; Christine Jard; Jacques Lucas; Jean Luc Adam; Pierre Brissot; Bruno Bureau; Olivier Loréal
Fiber evanescent wave spectroscopy using the mid-infrared provides useful fingerprints for metabolic profiling in humans.
Journal of biomedical optics 2009;14(5):054033.
2009: Marie-Bérengère Troadec; Fabrice Lainé; Vincent Daniel; Pierre Rochcongar; Martine Ropert; Florian Cabillic; Michèle Perrin; Jeff Morcet; Olivier Loréal; Gordana Olbina; Mark Westerman; Elizabeta Nemeth; Tomas Ganz; Pierre Brissot
Daily regulation of serum and urinary hepcidin is not influenced by submaximal cycling exercise in humans with normal iron metabolism.
European journal of applied physiology 2009;106(3):435-43.
2009: Marie-Laure Island; Anne-Marie Jouanolle; Annick Mosser; Yves Deugnier; Véronique David; Pierre Brissot; Olivier Loréal
A new mutation in the hepcidin promoter impairs its BMP response and contributes to a severe phenotype in HFE related hemochromatosis.
Haematologica 2009;94(5):720-4.
2009: Caroline Kannengiesser; Anne-Marie Jouanolle; Gilles Hetet; Annick Mosser; Françoise Muzeau; Dominique Henry; Edouard Bardou-Jacquet; Martine Mornet; Pierre Brissot; Yves Deugnier; Bernard Grandchamp; Carole Beaumont
A new missense mutation in the L ferritin coding sequence associated with elevated levels of glycosylated ferritin in serum and absence of iron overload.
Haematologica 2009;94(3):335-9.
2008: Anne Jolivet-Gougeon; Olivier Loréal; Anne Ingels; Bruno Danic; Martine Ropert; Edouard Bardou-Jacquet; Nourdin Aqodad; Françoise Aussant-Bertel; Claude Ferec; Pierre Brissot
Serum transferrin saturation increase is associated with decrease of antibacterial activity of serum in patients with HFE-related genetic hemochromatosis.
The American journal of gastroenterology 2008;103(10):2502-8.
2008: Pierre Brissot; marie-berengere troadec; Edouard Bardou-Jacquet; Caroline Le Lan; Anne-Marie Jouanolle; Yves Deugnier; Olivier Loréal
Current approach to hemochromatosis.
Blood reviews 2008;22(4):195-210.
2008: marie-berengere troadec; Alain Fautrel; Bernard Drénou; Patricia Leroyer; Emilie Camberlein; Bruno Turlin; André Guillouzo; Pierre Brissot; Olivier Loréal
Transcripts of ceruloplasmin but not hepcidin, both major iron metabolism genes, exhibit a decreasing pattern along the portocentral axis of mouse liver.
Biochimica et biophysica acta 2008;1782(4):239-49.
2008: Yves Deugnier; Pierre Brissot; Olivier Loréal
Iron and the liver: update 2008.
Journal of hepatology 2008;48 Suppl 1():S113-23.
2008: Emilie Camberlein; Giuliana Zanninelli; Lénaïck Détivaud; Anna Rita Lizzi; Francesco Sorrentino; Stefania Vacquer; marie-berengere troadec; Emanuele Angelucci; Emmanuelle Abgueguen; Olivier Loréal; Paolo Cianciulli; Maria Eliana Lai; Pierre Brissot
Anemia in beta-thalassemia patients targets hepatic hepcidin transcript levels independently of iron metabolism genes controlling hepcidin expression.
Haematologica 2008;93(1):111-5.
2007: Pierre Brissot
Diagnosis and current treatments for primary iron overload.
American journal of hematology 2007;82(12 Suppl):1140-1.
2007: Anne Jolivet-Gougeon; Anne Ingels; Bruno Danic; Françoise Aussant-Bertel; Claude Ferec; Olivier Loréal; Jacques Minet; Pierre Brissot
No increased seroprevalence of anti-Yersinia antibodies in patients with type 1 (C282Y/C282Y) hemochromatosis.
Scandinavian journal of gastroenterology 2007;42(11):1388-9.
2007: Gérard Lescoat; Karine Chantrel-Groussard; Nicole Pasdeloup; H Nick; Pierre Brissot; François Gaboriau
Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism.
Cell proliferation 2007;40(5):755-67.
2007: Jacqueline Milet; Valerie Dehais; Catherine Bourgain; Anne-Marie Jouanolle; Annick Mosser; Michèle Perrin; Jeff Morcet; Pierre Brissot; Veronique David; Yves Deugnier; Jean Mosser
Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance.
American journal of human genetics 2007;81(4):799-807.
2007: Pierre Brissot; Frédéric De Bels
[Management of hemochromatosis linked to HFE gene].
Presse médicale (Paris, France : 1983) 2007;36(9 Pt 2):1295-300.
2007: Olivier Loréal; Martine Ropert; Annick Mosser; Valérie Déhais; Yves Deugnier; Véronique David; Pierre Brissot; Anne-Marie Jouanolle
[Pathophysiology and genetics of classic HFE (type 1) hemochromatosis].
Presse médicale (Paris, France : 1983) 2007;36(9 Pt 2):1271-7.
2007: Olivier Loréal; Emilie Camberlein; Nadia Fatih; Pierre Brissot
[Controlling hemochromatosis, the course of hepcidine].
Soins; la revue de référence infirmière 2007;(716):55.
2007: Pierre Brissot; Edouard Bardou-Jacquet; Martine Ropert; Olivier Loréal
[Treatment of hemochromatosis and its complications].
Soins; la revue de référence infirmière 2007;(716):40-2.
2007: Dominique Guyader; Anne-Sophie Thirouard; Lars Erdtmann; Nafissa Rakba; Sylvie Jacquelinet; Hélène Danielou; Michèle Perrin; Anne-Marie Jouanolle; Pierre Brissot; Yves Deugnier
Liver iron is a surrogate marker of severe fibrosis in chronic hepatitis C.
Journal of hepatology 2007;46(4):587-95.
2006: Pierre Brissot; Michaël Bismuth; Edith Peynaud-Debayle; Frédéric de Bels
[Practical management of HFE hemochromatosis].
La Revue du praticien 2006;56(19):2123-9.
2006: Olivier Loréal; marie-berengere troadec; Emilie Camberlein; Nadia Fatih; Martine Ropert; Pierre Brissot
[Iron metabolism].
La Revue du praticien 2006;56(19):2111-7.
2006: François Gaboriau; Cindy Laupen-Chassay; Nicole Pasdeloup; Jean-Louis Pierre; Pierre Brissot; Gérard Lescoat
Modulation of cell proliferation and polyamine metabolism in rat liver cell cultures by the iron chelator O-trensox.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2006;19(6):623-32.
2006: Pierre Brissot; marie-berengere troadec; Caroline Le Lan; Richard Lorho; François Gaboriau; Gérard Lescoat; Anne-Marie Jouanolle; Olivier Loréal
[Genetic iron overload diseases: a deeply changing world].
Néphrologie & thérapeutique 2006;2 Suppl 5():S298-303.
2006: Olivier Loréal; Emilie Camberlein; marie-berengere troadec; Emmanuelle Abgueguen; Lenaïck Detivaud; Gérard Lescoat; François Gaboriau; Pierre Brissot
[Normal iron metabolism].
Néphrologie & thérapeutique 2006;2 Suppl 5():S290-7.
2006: Fabrice Lainé; Jean-Michel Reymann; Fabrice MOREL; S Langouët; Michèle Perrin; Anne Guillygomarc'h; Pierre Brissot; V Turmel; C Mouchel; Danielle Pape; Eric Bellissant; Yves Deugnier
Effects of phlebotomy therapy on cytochrome P450 2e1 activity and oxidative stress markers in dysmetabolic iron overload syndrome: a randomized trial.
Alimentary pharmacology & therapeutics 2006;24(8):1207-13.
2006: Ludivine Falize; Anne Guillygomarc'h; Michèle Perrin; Fabrice Lainé; Dominique Guyader; Pierre Brissot; Bruno Turlin; Yves Deugnier
Reversibility of hepatic fibrosis in treated genetic hemochromatosis: a study of 36 cases.
Hepatology (Baltimore, Md.) 2006;44(2):472-7.
2006: Karine Chantrel-Groussard; François Gaboriau; Nicole Pasdeloup; René Havouis; Hanspeter Nick; Jean-Louis Pierre; Pierre Brissot; Gérard Lescoat
The new orally active iron chelator ICL670A exhibits a higher antiproliferative effect in human hepatocyte cultures than O-trensox.
European journal of pharmacology 2006;541(3):129-37.
2006: marie-berengere troadec; Brice Courselaud; Lénaïck Détivaud; Christelle Haziza-Pigeon; Patricia Leroyer; Pierre Brissot; Olivier Loréal
Iron overload promotes Cyclin D1 expression and alters cell cycle in mouse hepatocytes.
Journal of hepatology 2006;44(2):391-9.
2006: Pierre Brissot; Frédéric de Bels
Current approaches to the management of hemochromatosis.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2006;():36-41.
2006: marie-berengere troadec; Denise Glaise; guillaume lamirault; Martine Le Cunff; Emilie Guérin; Nolwenn Le Meur; Lénaïck Détivaud; Pierre Zindy; Patricia Leroyer; Isabelle Guisle; Hélène Duval; Philippe Gripon; Nathalie Théret; Karim Boudjema; Christiane Guguen-Guillouzo; Pierre Brissot; Jean J Léger; Olivier Loréal
Hepatocyte iron loading capacity is associated with differentiation and repression of motility in the HepaRG cell line.
Genomics 2006;87(1):93-103.
2005: Lénaïck Détivaud; Elizabeta Nemeth; Karim Boudjema; Bruno Turlin; marie-berengere troadec; Patricia Leroyer; Martine Ropert; Sylvie Jacquelinet; Brice Courselaud; Tomas Ganz; Pierre Brissot; Olivier Loréal
Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function.
Blood 2005;106(2):746-8.
2005: Olivier Loréal; Christelle Haziza-Pigeon; marie-berengere troadec; Lénaïck Detivaud; Bruno Turlin; Brice Courselaud; Gennady Ilyin; Pierre Brissot
Hepcidin in iron metabolism.
Current protein & peptide science 2005;6(3):279-91.
2005: Pierre Brissot; Caroline Le Lan; marie-berengere troadec; Richard Lorho; Martine Ropert; Gérard Lescoat; Olivier Loréal
[HFE hemochromatosis: pathogenic and diagnostic approach].
Transfusion clinique et biologique : journal de la Société française de transfusion sanguine 2005;12(2):77-82.
2005: Caroline Le Lan; Olivier Loréal; Tally Cohen; Martine Ropert; Hava Glickstein; Fabrice Lainé; Michel Pouchard; Yves Deugnier; André LE TREUT; William Breuer; Ioav Cabantchik; Pierre Brissot
Redox active plasma iron in C282Y/C282Y hemochromatosis.
Blood 2005;105(11):4527-31.
2005: Pierre Brissot; Anne-Marie Jouanolle; Caroline Le Lan; Olivier Loreal; Yves Deugnier; Véronique David
[Non-HFE related hereditary iron overload].
Gastroentérologie clinique et biologique 2005;29(5):565-8.
2005: Patricia Aguilar-Martinez; Jean-François Schved; Pierre Brissot
The evaluation of hyperferritinemia: an updated strategy based on advances in detecting genetic abnormalities.
The American journal of gastroenterology 2005;100(5):1185-94.
2005: Pierre Brissot; Caroline Le Lan; Richard Lorho; François Gaboriau; Gérard Lescoat; Olivier Loréal
Genetic hemochromatosis update.
Acta gastro-enterologica Belgica 2005;68(1):33-7.
2004: Fabrice Lainé; Claude Bendavid; Romain Moirand; Sabrina Tessier; Michèle Perrin; Anne Guillygomarc'h; Dominique Guyader; Emmanuelle Calon; Alain Renault; Pierre Brissot; Bruno Turlin; Yves Deugnier
Prediction of liver fibrosis in patients with features of the metabolic syndrome regardless of alcohol consumption.
Hepatology (Baltimore, Md.) 2004;39(6):1639-46.
2004: Olivier Loréal; Caroline Le Lan; marie-berengere troadec; Dominique Guyader; Pierre Brissot
[Update on hemochromatosis].
Gastroentérologie clinique et biologique 2004;28(5 Suppl):D92-102.
2004: Caroline Le Lan; Martine Ropert; Fabrice Lainé; Muriel Medevielle; Christine Jard; Michel Pouchard; André LE TREUT; Romain Moirand; Olivier Loréal; Pierre Brissot
Serum ceruloplasmin and ferroxidase activity are not decreased in hepatic failure related to alcoholic cirrhosis: clinical and pathophysiological implications.
Alcoholism, clinical and experimental research 2004;28(5):775-9.
2004: François Gaboriau; Karine Chantrel-Groussard; Nafissa Rakba; Pascal Loyer; Nicole Pasdeloup; Robert C Hider; Pierre Brissot; Gérard Lescoat
Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study.
Biochemical pharmacology 2004;67(8):1479-87.
2004: Pierre Brissot; marie-berengere troadec; Olivier Loréal
Intestinal absorption of iron in HFE-1 hemochromatosis: local or systemic process?
Journal of hepatology 2004;40(4):702-9.
2004: Brice Courselaud; marie-berengere troadec; Séverine Fruchon; Gennady Ilyin; Nicolas Borot; Patricia Leroyer; Hélène Coppin; Pierre Brissot; Marie-Paule Roth; Olivier Loréal
Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice.
Blood cells, molecules & diseases 2004;32(2):283-9.
2004: Pierre Brissot; marie-berengere troadec; Olivier Loréal
The clinical relevance of new insights in iron transport and metabolism.
Current hematology reports 2004;3(2):107-15.
2004: George Papanikolaou; Mark E Samuels; Erwin H Ludwig; Marcia L E MacDonald; Patrick L Franchini; Marie-Pierre Dubé; Lisa Andres; Julie MacFarlane; Nikos Sakellaropoulos; Marianna Politou; Elizabeta Nemeth; Jay Thompson; Jenni K Risler; Catherine Zaborowska; Ryan Babakaiff; Christopher C Radomski; Terry D Pape; Owen Davidas; John Christakis; Pierre Brissot; Gillian Lockitch; Tomas Ganz; Michael R Hayden; Y Paul Goldberg
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis.
Nature genetics 2004;36(1):77-82.
2003: Eveline Boucher; Sylvie Jacquelinet; Valérie Canva; Bruno Turlin; Christian Jacquelinet; Ronald Colimon; Yves Deugnier; Dominique Guyader; Pierre Brissot
High rate of long-term virological response after a 1-year course of interferon +/- ribavirin in chronic hepatitis C relapsers. Results of a 191 patients randomized trial.
Liver international : official journal of the International Association for the Study of the Liver 2003;23(4):255-61.
2003: Anne-Marie Jouanolle; Véronique Douabin-Gicquel; Chantal Halimi; Olivier Loréal; Patricia Fergelot; Thierry Delacour; Anne-Sophie de Lajarte-Thirouard; Bruno Turlin; Jean-Yves Le Gall; Estelle Cadet; Jacques Rochette; Véronique David; Pierre Brissot
Novel mutation in ferroportin 1 gene is associated with autosomal dominant iron overload.
Journal of hepatology 2003;39(2):286-9.
2003: Gennady Ilyin; Brice Courselaud; marie-berengere troadec; Christelle Pigeon; Mehdi Alizadeh; Patricia Leroyer; Pierre Brissot; Olivier Loréal
Comparative analysis of mouse hepcidin 1 and 2 genes: evidence for different patterns of expression and co-inducibility during iron overload.
FEBS letters 2003;542(1-3):22-6.
2002: Pierre Brissot
[Practical use of genetic markers other than C282Y in iron overload disorders].
Gastroentérologie clinique et biologique 2002;26(11):991-3.
2002: Bruno Turlin; Danielle Le Quilleuc; Patricia Leroyer; Pierre Brissot; Yves Deugnier; Olivier Loréal
High vascular endothelial growth factor (VEGF) expression in chemically-induced hepatic microcancers in mice.
Journal of hepatology 2002;37(5):620-4.
2002: F Dupic; Séverine Fruchon; Mounia Bensaid; Olivier Loreal; Pierre Brissot; Nicolas Borot; Marie-Paule Roth; Hélène Coppin
Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice.
Gut 2002;51(5):648-53.
2002: Brice Courselaud; Christelle Pigeon; Yusuke Inoue; Junko Inoue; Frank J Gonzalez; Patricia Leroyer; David Gilot; Karim Boudjema; Christiane Guguen-Guillouzo; Pierre Brissot; Olivier Loréal; Gennady Ilyin
C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism.
The Journal of biological chemistry 2002;277(43):41163-70.
2002: Eveline Boucher; Stéphane Corbinais; Pierre Brissot; Karim Boudjema; Jean-Luc Raoul
Treatment of hepatocellular carcinoma (HCC) with systemic chemotherapy combining epirubicin, cisplatinum and infusional 5-fluorouracil (ECF regimen).
Cancer chemotherapy and pharmacology 2002;50(4):305-8.
2002: Romain Moirand; Dominique Guyader; Michel Henry Mendler; Anne-Marie Jouanolle; Jean Yves Le Gall; Véronique David; Pierre Brissot; Yves Deugnier
HFE based re-evaluation of heterozygous hemochromatosis.
American journal of medical genetics 2002;111(4):356-61.
2002: Olivier Loréal; Bruno Turlin; Christelle Pigeon; Annick Moisan; Martine Ropert; Patrick Morice; Yves Gandon; Anne-Marie Jouanolle; Marc Vérin; Robert C Hider; Kunihiro Yoshida; Pierre Brissot
Aceruloplasminemia: new clinical, pathophysiological and therapeutic insights.
Journal of hepatology 2002;36(6):851-6.
2002: Françoise Dupic; Séverine Fruchon; Mounia Bensaid; Nicolas Borot; Mirjana Radosavljevic; Olivier Loreal; Pierre Brissot; Susan Gilfillan; Seiamak Bahram; Hélène Coppin; Marie-Paule Roth
Inactivation of the hemochromatosis gene differentially regulates duodenal expression of iron-related mRNAs between mouse strains.
Gastroenterology 2002;122(3):745-51.
2002: Pierre Brissot; Olivier Loréal
Role of non-transferrin-bound iron in the pathogenesis of iron overload and toxicity.
Advances in experimental medicine and biology 2002;509():45-53.
2002: Pierre Brissot; Fabrice Lainé; Anne Guillygomarc'h; Dominique Guyader; Olivier Loréal; Yves Deugnier; Romain Moirand
[How to confirm and treat hemochromatosis in 2002?].
Journées annuelles de diabétologie de l'Hôtel-Dieu 2002;():69-82.
2002: Olivier Loréal; marie-berengere troadec; Brice Courselaud; Pierre Brissot
[Iron metabolism: new genes for historical diseases].
Journées annuelles de diabétologie de l'Hôtel-Dieu 2002;():43-54.
2002: Bartholomeus Johannes Veldt; Fabrice Lainé; Anne Guillygomarc'h; Laurence Lauvin; Karim Boudjema; Michel Messner; Pierre Brissot; Yves Deugnier; Romain Moirand
Indication of liver transplantation in severe alcoholic liver cirrhosis: quantitative evaluation and optimal timing.
Journal of hepatology 2002;36(1):93-8.
2002: Fabrice Lainé; Martine Ropert; Caroline Le Lan; Olivier Loréal; Eric Bellissant; Christine Jard; Michel Pouchard; André LE TREUT; Pierre Brissot
Serum ceruloplasmin and ferroxidase activity are decreased in HFE C282Y homozygote male iron-overloaded patients.
Journal of hepatology 2002;36(1):60-5.
2002: Giuliana Zanninelli; Olivier Loréal; Pierre Brissot; Abraham M Konijn; Itzchak Slotki; Robert C Hider; Z Ioav Cabantchik
The labile iron pool of hepatocytes in chronic and acute iron overload and chelator-induced iron deprivation.
Journal of hepatology 2002;36(1):39-46.
2001: Anne Guillygomarc'h; Michel Henry Mendler; Romain Moirand; Fabrice Lainé; V Quentin; Véronique David; Pierre Brissot; Yves Deugnier
Venesection therapy of insulin resistance-associated hepatic iron overload.
Journal of hepatology 2001;35(3):344-9.
2001: Christelle Pigeon; Philippe Legrand; Patricia Leroyer; Monique Bouriel; Bruno Turlin; Pierre Brissot; Olivier Loréal
Stearoyl coenzyme A desaturase 1 expression and activity are increased in the liver during iron overload.
Biochimica et biophysica acta 2001;1535(3):275-84.
2001: Christelle Pigeon; Gennady Ilyin; Brice Courselaud; Patricia Leroyer; Bruno Turlin; Pierre Brissot; Olivier Loréal
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload.
The Journal of biological chemistry 2001;276(11):7811-9.
2001: S Sachot; Romain Moirand; Anne-Marie Jouanolle; Jean Mosser; Patricia Fergelot; Yves Deugnier; Pierre Brissot; Jean-Yves Le Gall; Véronique David
Low penetrant hemochromatosis phenotype in eight families: no evidence of modifiers in the MHC region.
Blood cells, molecules & diseases 2001;27(2):518-29.
2001: P Chouteau; Jacques Le Seyec; B Saulier-Le Dréan; Isabelle Cannie; Pierre Brissot; Gérard Lescoat; Christiane Guguen-Guillouzo; Philippe Gripon
Inhibition of hepatitis B virus production associated with high levels of intracellular viral DNA intermediates in iron-depleted HepG2.2.15 cells.
Journal of hepatology 2001;34(1):108-13.
2000: Romain Moirand; Michel Henry Mendler; Anne Guillygomarc'h; Pierre Brissot; Yves Deugnier
Non-alcoholic steatohepatitis with iron: part of insulin resistance-associated hepatic iron overload?
Journal of hepatology 2000;33(6):1024-6.
2000: Pierre Brissot; Dominique Guyader; Olivier Loréal; Fabrice Lainé; Anne Guillygomarc'h; Romain Moirand; Yves Deugnier
Clinical aspects of hemochromatosis.
Transfusion science 2000;23(3):193-200.
2000: Olivier Loreal; Christelle Pigeon; Yves Deugnier; Pierre Brissot
[Iron metabolism].
Gastroentérologie clinique et biologique 2000;24(5 Pt 2):B56-61.
2000: Romain Moirand; Anne Guillygomarc'h; Pierre Brissot; Yves Deugnier
[Diagnosis and treatment of genetic hemochromatosis].
La Revue du praticien 2000;50(9):977-82.
2000: Pierre Brissot; Fabrice Lainé; Romain Moirand; Olivier Loréal
[Genetics and physiopathology of hemochromatosis].
La Revue du praticien 2000;50(9):972-6.
2000: Nafissa Rakba; Pascal Loyer; David Gilot; Jean-Guy Delcros; Denise Glaise; Paul Baret; Jean-Louis Pierre; Pierre Brissot; Gérard Lescoat
Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines.
Carcinogenesis 2000;21(5):943-51.
2000: Thierry Sapey; Michel Henry Mendler; Dominique Guyader; Olivia Morio; Stéphane Corbinais; Yves Deugnier; Pierre Brissot
Respective value of alkaline phosphatase, gamma-glutamyl transpeptidase and 5' nucleotidase serum activity in the diagnosis of cholestasis: a prospective study of 80 patients.
Journal of clinical gastroenterology 2000;30(3):259-63.
2000: Eveline Boucher; Dominique Guyader; Sylvie Jacquelinet; P Andre; Michel Henry Mendler; Bruno Turlin; Valérie Canva; Jean-Baptiste Nousbaum; Pierre-Henri Bernard; O Nouel; J J Raabe; T Dao; P Gasser; P Verger; J Boutin; P Bergerault; F Joram; P Colmar; Michel Messner; Pierre Brissot; Yves Deugnier
Interferon and ursodeoxycholic acid combined therapy in chronic viral C hepatitis: controlled randomized trial in 203 patients.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2000;32(1):29-33.
1999: Michel Henry Mendler; Stéphane Corbinais; Thierry Sapey; C Lucas-Clerc; V Tiisma; Dominique Guyader; Yves Deugnier; André LE TREUT; Pierre Brissot
In patients with cirrhosis, serum albumin determination should be carried out by immunonephelometry rather than by protein electrophoresis.
European journal of gastroenterology & hepatology 1999;11(12):1405-11.
1999: Yves Deugnier; Romain Moirand; Pierre Brissot; V David
[Iron in the era of molecular biology].
Pathologie-biologie 1999;47(9):938-44.
1999: Michel Henry Mendler; Bruno Turlin; Romain Moirand; Anne-Marie Jouanolle; Thierry Sapey; Dominique Guyader; J Y Le Gall; Pierre Brissot; V David; Yves Deugnier
Insulin resistance-associated hepatic iron overload.
Gastroenterology 1999;117(5):1155-63.
1999: Nafissa Rakba; M K Nguyen-Van-Duong; L Nicolas; V Guillot; I Morel; Nicole Pasdeloup; Pierre Brissot; Gérard Lescoat
Cytoprotection and iron mobilization in rat hepatocyte cultures by a new synthetic dihydroxamate chelator.
Toxicology letters 1999;110(1-2):19-27.
1999: Véronique David; Anne-Marie Jouanolle; Patricia Fergelot; Pierre Brissot; Yves Deugnier; Jean-Yves Le Gall
[Molecular genetics of hemochromatosis].
Annales d'endocrinologie 1999;60(3):204-9.
1999: Olivier Loréal; Christelle Pigeon; Giuliana Zanninelli; Bruno Turlin; Gérard Lescoat; Yves Deugnier; Pierre Brissot
[Current data on iron metabolism].
Annales d'endocrinologie 1999;60(3):197-203.
1999: Dominique Guyader; Eveline Boucher; P André; C Even; J Cottereau; A Bianchi; P Gasser; Michel Henry Mendler; Yves Deugnier; Pierre Brissot
A pilot study of iron depletion as adjuvant therapy in chronic hepatitis C patients not responding to interferon.
The American journal of gastroenterology 1999;94(6):1696-8.
1999: Christelle Pigeon; Bruno Turlin; Theodore C Iancu; Patricia Leroyer; J Le Lan; Yves Deugnier; Pierre Brissot; Olivier Loréal
Carbonyl-iron supplementation induces hepatocyte nuclear changes in BALB/CJ male mice.
Journal of hepatology 1999;30(5):926-34.
1999: Hervé Allain; Stéphane Schück; S Lebreton; A Strenge-Hesse; W Braun; Jean-Marc Gandon; Pierre Brissot
Aminotransferase levels and silymarin in de novo tacrine-treated patients with Alzheimer's disease.
Dementia and geriatric cognitive disorders 1999;10(3):181-5.
1999: Dominique Guyader; Yves Gandon; Thierry Sapey; Bruno Turlin; Michel Henry Mendler; Pierre Brissot; Yves Deugnier
Magnetic resonance iron-free nodules in genetic hemochromatosis.
The American journal of gastroenterology 1999;94(4):1083-6.
1999: Thierry Sapey; Bruno Turlin; V Canva-Delcambre; Michel Henry Mendler; Yves Deugnier; Pierre Brissot; Dominique Guyader
[Importance of liver puncture biopsy and endoscopic retrograde cholangiography in patients with chronic anicteric unexplained cholestasis. A retrospective study in 79 patients].
Gastroentérologie clinique et biologique 1999;23(2):178-85.
1999: Romain Moirand; Anne-Marie Jouanolle; Pierre Brissot; J Y Le Gall; V David; Yves Deugnier
Phenotypic expression of HFE mutations: a French study of 1110 unrelated iron-overloaded patients and relatives.
Gastroenterology 1999;116(2):372-7.
1999: Yves Deugnier; Romain Moirand; Dominique Guyader; Anne-Marie Jouanolle; Pierre Brissot
[Iron overload and HFE gene].
Gastroentérologie clinique et biologique 1999;23(1):122-31.
1998: Dominique Guyader; Christian Jacquelinet; Romain Moirand; Bruno Turlin; Michel Henry Mendler; Jacques Chaperon; V David; Pierre Brissot; P Adams; Yves Deugnier
Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis.
Gastroenterology 1998;115(4):929-36.
1998: N Chenoufi; B Drénou; Olivier Loréal; Christelle Pigeon; Pierre Brissot; Gérard Lescoat
Antiproliferative effect of deferiprone on the Hep G2 cell line.
Biochemical pharmacology 1998;56(4):431-7.
1998: Pierre Brissot; Christelle Pigeon; Romain Moirand; Dominique Guyader; Michel Henry Mendler; Thierry Sapey; Yves Deugnier; Gérard Lescoat; Olivier Loréal
[Iron metabolism and its exploration in clinical biology].
Annales de biologie clinique 1998;56 Spec No():5-10.
1998: Nafissa Rakba; F Aouad; C Henry; C Caris; I Morel; Paul Baret; Jean-Louis Pierre; Pierre Brissot; Roberta J Ward; Gérard Lescoat; Robert R Crichton
Iron mobilisation and cellular protection by a new synthetic chelator O-Trensox.
Biochemical pharmacology 1998;55(11):1797-806.
1998: N Chenoufi; Jean-Luc Raoul; Gérard Lescoat; Pierre Brissot; Patrick Bourguet
In vitro demonstration of synergy between radionuclide and chemotherapy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(5):900-3.
1998: Dominique Guyader; C Lefeuvre; Sylvie Jacquelinet; M Prat; Y Baudouard; Bruno Turlin; P André; Michel Henry Mendler; Thierry Sapey; Eveline Boucher; Romain Moirand; Michel Messner; Ronald Colimon; Pierre Brissot; Yves Deugnier
[Epidemiology of hepatitis C virus infection in 1,304 HCV positive patients: variations according to the origin of transmission and year of diagnosis].
Gastroentérologie clinique et biologique 1998;22(4):375-80.
1998: N Chenoufi; Georges Baffet; B Drénou; S Cariou; Mireille Desille; Bruno Clément; Pierre Brissot; Gérard Lescoat; Olivier Loréal
Deferoxamine arrests in vitro the proliferation of porcine hepatocyte in G1 phase of the cell cycle.
Liver 1998;18(1):60-6.
1997: Theodore C Iancu; Yves Deugnier; JW Halliday; Lawrie W Powell; Pierre Brissot
Ultrastructural sequences during liver iron overload in genetic hemochromatosis.
Journal of hepatology 1997;27(4):628-38.
1997: Romain Moirand; P C Adams; V Bicheler; Pierre Brissot; Yves Deugnier
Clinical features of genetic hemochromatosis in women compared with men.
Annals of internal medicine 1997;127(2):105-10.
1997: Giuliana Zanninelli; R Choudury; Olivier Loréal; Dominique Guyader; Gérard Lescoat; J Arnaud; Roberto Verna; B Cosson; S Singh; Robert C Hider; Pierre Brissot
Novel orally active iron chelators (3-hydroxypyridin-4-ones) enhance the biliary excretion of plasma non-transferrin-bound iron in rats.
Journal of hepatology 1997;27(1):176-84.
1997: Yves Deugnier; Bruno Turlin; D le Quilleuc; Romain Moirand; Olivier Loréal; Michel Messner; Bernard Meunier; Pierre Brissot; Bernard Launois
A reappraisal of hepatic siderosis in patients with end-stage cirrhosis: practical implications for the diagnosis of hemochromatosis.
The American journal of surgical pathology 1997;21(6):669-75.
1997: Giuliana Zanninelli; Hava Glickstein; William Breuer; P Milgram; Pierre Brissot; Robert C Hider; Abraham M Konijn; J Libman; Abraham Shanzer; Ioav Cabantchik
Chelation and mobilization of cellular iron by different classes of chelators.
Molecular pharmacology 1997;51(5):842-52.
1997: P Jégo; N Chenoufi; Olivier Loréal; I Morel; Nicole Pasdeloup; M A Abdallah; Pierre Brissot; Gérard Lescoat
Inhibition of iron toxicity in human hepatocyte cultures by pyoverdins Pa A and Pf, the peptidic siderophores of Pseudomonas aeruginosa and fluorescens.
Liver 1997;17(2):70-5.
1997: N Chenoufi; Olivier Loréal; B Drénou; S Cariou; N Hubert; Patricia Leroyer; Pierre Brissot; Gérard Lescoat
Iron may induce both DNA synthesis and repair in rat hepatocytes stimulated by EGF/pyruvate.
Journal of hepatology 1997;26(3):650-8.
1997: Olivier Loréal; N Chenoufi; Bruno Turlin; Christelle Haziza-Pigeon; J Y Robert; Gérard Lescoat; H Mathiex-Fortunet; Yves Deugnier; Pierre Brissot
Effect of ursodeoxycholic acid on liver iron stores and distribution in rats with normal or iron-supplemented diet.
Liver 1997;17(1):30-4.
1997: Thierry Sapey; Dominique Guyader; Pierre Brissot
[Symptomatic treatment of pruritus in cholestasis].
Gastroentérologie clinique et biologique 1997;21(6-7):472-80.
1997: Thierry Sapey; Dominique Guyader; J F Bretagne; Yves Deugnier; Pierre Brissot
[Respective value of serum activity of alkaline phosphatase, gamma-glutamyl transpeptidase and 5'-nucleotidase in the diagnosis of intra- and extrahepatic cholestasis].
Gastroentérologie clinique et biologique 1997;21(4):339-40.
1997: Pierre Brissot
[How should hepatitis C be treated? Treatment of chronic hepatitis C with therapeutic combinations].
Gastroentérologie clinique et biologique 1997;21(1 Pt 2):S89-95.
1995: Eveline Boucher; A Kerlirzin; Bruno Turlin; Pierre Brissot; Yves Deugnier
[Acute cholangitis caused by an amoxicillin-clavulanic acid combination].
Gastroentérologie clinique et biologique 1995;19(11):957-8.
1995: Romain Moirand; F Kerdavid; Olivier Loréal; N Hubert; Patricia Leroyer; Pierre Brissot; Gérard Lescoat
Regulation of ferritin expression by alcohol in a human hepatoblastoma cell line and in rat hepatocyte cultures.
Journal of hepatology 1995;23(4):431-9.
1995: Bruno Turlin; F Juguet; Romain Moirand; D Le Quilleuc; Olivier Loréal; J P Campion; Bernard Launois; M P Ramée; Pierre Brissot; Yves Deugnier
Increased liver iron stores in patients with hepatocellular carcinoma developed on a noncirrhotic liver.
Hepatology (Baltimore, Md.) 1995;22(2):446-50.
1995: N Chenoufi; N Hubert; Olivier Loréal; I Morel; Nicole Pasdeloup; Josiane Cillard; Pierre Brissot; Gérard Lescoat
Inhibition of iron toxicity in rat and human hepatocyte cultures by the hydroxypyridin-4-ones CP20 and CP94.
Journal of hepatology 1995;23(2):166-73.
1995: Eveline Boucher; H Jouanolle; P Andre; Annick Ruffault; Dominique Guyader; Romain Moirand; Bruno Turlin; Christian Jacquelinet; Pierre Brissot; Yves Deugnier
Interferon and ursodeoxycholic acid combined therapy in the treatment of chronic viral C hepatitis: results from a controlled randomized trial in 80 patients.
Hepatology (Baltimore, Md.) 1995;21(2):322-7.
1995: V Canva-Delcambre; Dominique Guyader; G Le Dréau; P Osmont; Romain Moirand; Yves Deugnier; Pierre Brissot
[Liver abscess caused by Yersinia enterocolitica with spontaneously favourable course].
Gastroentérologie clinique et biologique 1995;19(2):225-6.
1995: I Morel; Odile Sergent; P Cogrel; Gérard Lescoat; Nicole Pasdeloup; Pierre Brissot; Pierre Cillard; Josiane Cillard
EPR study of antioxidant activity of the iron chelators pyoverdin and hydroxypyrid-4-one in iron-loaded hepatocyte culture: comparison with that of desferrioxamine.
Free radical biology & medicine 1995;18(2):303-10.
1995: Odile Sergent; I Morel; P Cogrel; Martine Chevanne; Nicole Pasdeloup; Pierre Brissot; Gérard Lescoat; Pierre Cillard; Josiane Cillard
Increase in cellular pool of low-molecular-weight iron during ethanol metabolism in rat hepatocyte cultures. Relationship with lipid peroxidation.
Biological trace element research 1995;47(1-3):185-92.
1994: Y Gandon; Dominique Guyader; JF Heautot; M I Reda; Jacqueline Yaouanq; T Buhé; Pierre Brissot; Michel Carsin; Yves Deugnier
Hemochromatosis: diagnosis and quantification of liver iron with gradient-echo MR imaging.
Radiology 1994;193(2):533-8.
1994: Yves Deugnier; A F Rabot; Dominique Guyader; Romain Moirand; Bruno Turlin; Eveline Boucher; P Lebert; Pierre Brissot
Serum increase and liver overexpression of carbohydrate 19.9 antigen in patients with genetic haemochromatosis.
Gut 1994;35(8):1107-11.
1994: Pierre Brissot; Giuliana Zanninelli; Dominique Guyader; J Zeind; John L Md Gollan
Biliary excretion of plasma non-transferrin-bound iron in rats: pathogenetic importance in iron-overload disorders.
The American journal of physiology 1994;267(1 Pt 1):G135-42.
1994: Pierre Brissot; Yves Deugnier; Dominique Guyader; Giuliana Zanninelli; Olivier Loréal; Romain Moirand; Gérard Lescoat
Iron overload and the biliary route.
Advances in experimental medicine and biology 1994;356():277-83.
1994: D Carré; Eveline Boucher; Bruno Turlin; Dominique Guyader; Pierre Brissot; Yves Deugnier
[Decrease of cholesterolemia and apolipoprotein B in chronic viral hepatitis C with massive steatosis].
Gastroentérologie clinique et biologique 1994;18(10):899-900.
1993: Yves Deugnier; P Charalambous; D Le Quilleuc; Bruno Turlin; J Searle; Pierre Brissot; L W Powell; J W Halliday
Preneoplastic significance of hepatic iron-free foci in genetic hemochromatosis: a study of 185 patients.
Hepatology (Baltimore, Md.) 1993;18(6):1363-9.
1993: N Hubert; Gérard Lescoat; R Sciot; Romain Moirand; P Jego; Patricia Leroyer; Pierre Brissot
Regulation of ferritin and transferrin receptor expression by iron in human hepatocyte cultures.
Journal of hepatology 1993;18(3):301-12.
1993: Odile Sergent; I Morel; P Cogrel; Martine Chevanne; Nicole Pasdeloup; Pierre Brissot; Gérard Lescoat; Pierre Cillard; Josiane Cillard
Simultaneous measurements of conjugated dienes and free malondialdehyde, used as a micromethod for the evaluation of lipid peroxidation in rat hepatocyte cultures.
Chemistry and physics of lipids 1993;65(2):133-9.
1993: P Cogrel; I Morel; Gérard Lescoat; Martine Chevanne; Pierre Brissot; Pierre Cillard; Josiane Cillard
The relationship between fatty acid peroxidation and alpha-tocopherol consumption in isolated normal and transformed hepatocytes.
Lipids 1993;28(2):115-9.
1993: I Morel; Gérard Lescoat; P Cogrel; Odile Sergent; Nicole Pasdeloup; Pierre Brissot; Pierre Cillard; Josiane Cillard
Antioxidant and iron-chelating activities of the flavonoids catechin, quercetin and diosmetin on iron-loaded rat hepatocyte cultures.
Biochemical pharmacology 1993;45(1):13-9.
1993: P Jégo; N Hubert; Romain Moirand; I Morel; N Pasdeloup; A Ocaktan; M Abdallah; Pierre Brissot; Gérard Lescoat
Inhibition of iron toxicity in rat hepatocyte cultures by pyoverdin Pa A, the peptidic fluorescent siderophore of Pseudomonas aeruginosa.
Toxicology in vitro : an international journal published in association with BIBRA 1993;7(1):55-60.
1993: Yves Deugnier; Bruno Turlin; L W Powell; K M Summers; Romain Moirand; L Fletcher; Olivier Loréal; Pierre Brissot; J W Halliday
Differentiation between heterozygotes and homozygotes in genetic hemochromatosis by means of a histological hepatic iron index: a study of 192 cases.
Hepatology (Baltimore, Md.) 1993;17(1):30-4.
1992: I Morel; Josiane Cillard; Gérard Lescoat; Odile Sergent; Nicole Pasdeloup; A Z Ocaktan; Mohamed A Abdallah; Pierre Brissot; Pierre Cillard
Antioxidant and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: comparison of their mechanism of protection with that of desferrioxamine.
Free radical biology & medicine 1992;13(5):499-508.
1992: Olivier Loréal; Yves Deugnier; Romain Moirand; L Lauvin; Dominique Guyader; H Jouanolle; Bruno Turlin; Gérard Lescoat; Pierre Brissot
Liver fibrosis in genetic hemochromatosis. Respective roles of iron and non-iron-related factors in 127 homozygous patients.
Journal of hepatology 1992;16(1-2):122-7.
1992: Dominique Guyader; Y Gandon; J Y Robert; JF Heautot; H Jouanolle; Christian Jacquelinet; Michel Messner; Yves Deugnier; Pierre Brissot
Magnetic resonance imaging and assessment of liver iron content in genetic hemochromatosis.
Journal of hepatology 1992;15(3):304-8.
1992: Yves Deugnier; Olivier Loréal; Bruno Turlin; Dominique Guyader; H Jouanolle; Romain Moirand; Christian Jacquelinet; Pierre Brissot
Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations.
Gastroenterology 1992;102(6):2050-9.
1992: P Jego; N Hubert; I Morel; Nicole Pasdeloup; A Ocaktan; Mohamed A Abdallah; Pierre Brissot; Gérard Lescoat
Inhibition of iron overload toxicity in rat hepatocyte cultures by pyoverdin Pf, the siderophore of Pseudomonas fluorescens.
Biochemical pharmacology 1992;43(6):1275-80.
1992: Dominique Guyader; Giuliana Zanninelli; Pierre Brissot
[Non-transferrin-bound iron and hepatic iron load].
Gastroentérologie clinique et biologique 1992;16(10):756-9.
1992: Bruno Turlin; O Loreal; Romain Moirand; Pierre Brissot; Yves Deugnier; Marie-Paule Ramee
[Histochemical detection of hepatic iron. A comparative study of four stains].
Annales de pathologie 1992;12(6):371-3.
1991: Romain Moirand; Gérard Lescoat; D Delamaire; L Lauvin; J P Campion; Y Deugnier; Pierre Brissot
Increase in glycosylated and nonglycosylated serum ferritin in chronic alcoholism and their evolution during alcohol withdrawal.
Alcoholism, clinical and experimental research 1991;15(6):963-9.
1991: Yves Deugnier; D Battistelli; H Jouanolle; Dominique Guyader; M Gueguen; Olivier Loréal; Christian Jacquelinet; M Bourel; Pierre Brissot
Hepatitis B virus infection markers in genetic haemochromatosis. A study of 272 patients.
Journal of hepatology 1991;13(3):286-90.
1991: Dominique Guyader; H Jouanolle; Pierre Brissot
[Metabolic cirrhosis (hemochromatosis, Wilson's disease, erythropoietic protoporphyria)].
La Revue du praticien 1991;41(13):1166-9.
1991: Pierre Brissot; Christian Jacquelinet; H Jouanolle; V David; Dominique Guyader; M Guéguen; M Blayau; Gérard Lescoat; Michel Messner; Yves Deugnier
Short-term prednisolone followed by recombinant human alpha-interferon alone or combined with adenine-arabinoside in chronic hepatitis B. A prospective and randomized trial.
Journal of hepatology 1991;12(2):181-9.
1991: Gérard Lescoat; N Hubert; Romain Moirand; P Jego; Nicole Pasdeloup; Pierre Brissot
Iron load increases ferritin synthesis and secretion in adult human hepatocyte cultures.
Liver 1991;11(1):24-9.
1991: L Siproudhis; M Beaugrand; Yannick Malledant; Pierre Brissot; Christiane Guguen-Guillouzo; André Guillouzo
Use of adult human hepatocytes in primary culture for the study of clometacin-induced immunoallergic hepatitis.
Toxicology in vitro : an international journal published in association with BIBRA 1991;5(5-6):529-34.
1990: Romain Moirand; Gérard Lescoat; N Hubert; J F Dezier; Nicole Pasdeloup; Pierre Brissot
Alcohol induction of ferritin expression in a human hepatoblastoma cell line (HEP G2).
Alcoholism, clinical and experimental research 1990;14(6):847-52.
1990: H Jouanolle; Pierre Brissot
[Transmission of viruses (from A to E) and prevention].
La Revue du praticien 1990;40(18):1660-6.
1990: I Morel; Gérard Lescoat; Josiane Cillard; Nicole Pasdeloup; Pierre Brissot; Pierre Cillard
Kinetic evaluation of free malondialdehyde and enzyme leakage as indices of iron damage in rat hepatocyte cultures. Involvement of free radicals.
Biochemical pharmacology 1990;39(11):1647-55.
1990: H Jouanolle; Bruno Turlin; Dominique Guyader; Yves Deugnier; Pierre Brissot
[Association of sarcoidosis and primary biliary cirrhosis: review of the literature apropos of a new case].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 1990;11(3):252-5.
1990: Dominique Guyader; Y Gandon; Yves Deugnier; H Jouanolle; O Loreal; Michel Carsin; Pierre Brissot
[The value of computerized tomography in the assessment of hepatic iron overload in genetic hemochromatosis].
Annales de gastroentérologie et d'hépatologie 1990;26(1):21-5.
1990: Pierre Brissot; Yves Deugnier; G Lescoat
[Current data on iron overload].
Annales de chirurgie 1990;44(6):417-22.
1990: Dominique Guyader; Yves Deugnier; Pierre Brissot
[Primary sclerosing cholangitis].
Gastroentérologie clinique et biologique 1990;14(11):850-60.
1989: Dominique Guyader; Y Gandon; Yves Deugnier; H Jouanolle; O Loreal; M Simon; M Bourel; Michel Carsin; Pierre Brissot
Evaluation of computed tomography in the assessment of liver iron overload. A study of 46 cases of idiopathic hemochromatosis.
Gastroenterology 1989;97(3):737-43.
1989: B Desvergne; Georges Baffet; Pascal Loyer; Mary Rissel; Gérard Lescoat; Christiane Guguen-Guillouzo; Pierre Brissot
Chronic iron overload inhibits protein secretion by adult rat hepatocytes maintained in long-term primary culture.
European journal of cell biology 1989;49(1):162-70.
1989: Gérard Lescoat; O Loreal; Romain Moirand; J F Dezier; Nicole Pasdeloup; Yves Deugnier; Pierre Brissot
Iron induction of ferritin synthesis and secretion in human hepatoma cell (Hep G2) cultures.
Liver 1989;9(3):179-85.
1989: Gérard Lescoat; H Jouanolle; B Desvergne; Nicole Pasdeloup; B Kneip; Yves Deugnier; A Guillouzo; Pierre Brissot
Effects of iron overload on transferrin secretion by cultured fetal rat hepatocytes.
Biology of the cell / under the auspices of the European Cell Biology Organization 1989;65(3):221-9.
1989: Gérard Lescoat; B Desvergne; O Loreal; Nicole Pasdeloup; Yves Deugnier; M Bourel; Pierre Brissot
Modulation of albumin secretion by ornithine alpha-ketoglutarate in adult rat hepatocyte cultures and a human hepatoma cell line (HepG2).
Annals of nutrition & metabolism 1989;33(5):252-60.
1988: Gérard Lescoat; O Loreal; B Desvergne; Nicole Pasdeloup; Yves Deugnier; Pierre Brissot
Effect of ornithine on transferrin secretion of rat and human hepatocyte cultures.
Liver 1988;8(6):360-5.
1988: D Heresbach; Yves Deugnier; Pierre Brissot; M Bourel
[Sinusoid dilatation and the use of oral contraceptives. Apropos of a case with a review of the literature].
Annales de gastroentérologie et d'hépatologie 1988;24(4):189-91.
1987: H Jouanolle; Gérard Lescoat; B Desvergne; Yves Deugnier; Pierre Brissot; M Bourel
[Iron overload of the liver and protein synthesis. Progress made through experimental models].
Annales de gastroentérologie et d'hépatologie 1987;23(5):269-72.
1987: Pierre Brissot; J Farjanel; D Bourel; J P Campion; A Guillouzo; A Rattner; Yves Deugnier; B Desvergne; B Ferrand; M Simon
Chronic liver iron overload in the baboon by ferric nitrilotriacetate. Morphologic and functional changes with special reference to collagen synthesis enzymes.
Digestive diseases and sciences 1987;32(6):620-7.
1986: H Jouanolle; D Delamaire; Yves Deugnier; D Lhéry; M Simon; Pierre Brissot; M Bourel
[Randomized trial of elliptinium acetate and tamoxifen in the treatment of inoperable hepatocellular carcinoma].
Gastroentérologie clinique et biologique 1986;10(2):185-7.
1985: M Bourel; M Simon; Yves Deugnier; M Messner; D Delamaire; Pierre Brissot
[Idiopathic hemochromatosis in 1984].
Acta gastro-enterologica Belgica 1985;48(3):268-77.
1985: M Messner; Yves Deugnier; I Bernard-Griffiths; D Delamaire; P Estable; J L Friguet; M Le Gall; Pierre Brissot; M Bourel
[Value of ultrasound-guided cytopuncture in the diagnosis of tumors in cirrhosis. Study of 29 cases].
Gastroentérologie clinique et biologique 1985;9(1):42-6.
1984: J L Friguet; Yves Deugnier; M Messner; R Lauvin; B Launois; Pierre Brissot; B Ferrand; M Bourel
[Regenerative nodular hyperplasia in scleroderma : a new case].
Gastroentérologie clinique et biologique 1984;8(12):979.
1984: Yves Deugnier; V David; Pierre Brissot; P Mabo; D Delamaire; M Messner; M Bourel; J Y Legall
Serum alpha-L-fucosidase: a new marker for the diagnosis of primary hepatic carcinoma?
Hepatology (Baltimore, Md.) 1984;4(5):889-92.
1984: C Couet; Pierre Brissot; M Messner; D Delamaire; S Gie; M Bourel
Fractional clearance of bromosulfonephthalein and metabolic clearance of antipyrine. Correlative study in liver diseases.
Annales de gastroentérologie et d'hépatologie 1984;20(1):1-6.
1983: M Messner; S Pelletier; C Loisance; J L Friguet; Pierre Brissot; M Bourel
[Hepatic fascioliasis. Echotomographic appearance at an early stage].
Gastroentérologie clinique et biologique 1983;7(8-9):753.
1983: Pierre Brissot; J P Campion; A Guillouzo; H Allain; M Messner; M Simon; B Ferrand; M Bourel
Experimental hepatic iron overload in the baboon: results of a two-year study. Evolution of biological and morphologic hepatic parameters of iron overload.
Digestive diseases and sciences 1983;28(7):616-24.
1983: Yves Deugnier; V David; Pierre Brissot; P Mabo; B Ferrand; M Bourel; J Y Legall
[Alpha-L-fucosidase. A new marker of primary liver cancer?].
Presse médicale (Paris, France : 1983) 1983;12(8):523-4.
1983: J Farjanel; C Périer; Pierre Brissot; J P Campion; M Simon; B Ferrand; M Bourel
[Course of the prolyl hydroxylase activity and the quantity of collagen amino acids in the liver during a 2-year experimental chronic iron overload in baboons].
Gastroentérologie clinique et biologique 1983;7(1):75-80.
1982: Pierre Brissot; S Gie; A Colobert; D Delamaire; F Cartier; M Bourel
[A new case of hepatitis due to glafenine].
Gastroentérologie clinique et biologique 1982;6(11):948.
1982: Pierre Brissot; Y Le Du; M Messner; G Babatasi; D Delamaire; M Bourel
[Horton's disease and hepatic involvement simulating secondary cancer of the liver].
Gastroentérologie clinique et biologique 1982;6(5):513-5.
1982: Yves Deugnier; S Margules; Pierre Brissot; M A Deugnier; J C Bisconte; M Bourel; B Ferrand
Comparative study between biochemical and histological methods and image analysis in liver iron overload.
Journal of clinical pathology 1982;35(1):45-51.
1981: Pierre Brissot; M Bourel; D Herry; J P Verger; M Messner; C Beaumont; F Regnouard; B Ferrand; M Simon
Assessment of liver iron content in 271 patients: a reevaluation of direct and indirect methods.
Gastroenterology 1981;80(3):557-65.
1981: B Ferrand; Pierre Brissot; Yves Deugnier; D Herry; M Bourel
[Histologic classification of hepatic siderosis (author's transl)].
Archives d'anatomie et de cytologie pathologiques 1981;29(5):315-6.