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Eric Verdin

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TOP 3
Philipp Gut; Eric Verdin
Rejuvenating SIRT1 Activators.
Matthew J Rardin; Birgit Schilling; Dylan J Sorensen; Eric Verdin; Jason M Held; C Ronald Kahn; Biao Li; Sean D Mooney; John C Newman; Michael P Cusack; Bradford W Gibson
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
Philip I Merksamer; Danica Chen; Wenjuan He; Matthew David Hirschey; Yufei Liu; Eric Verdin
The sirtuins, oxidative stress and aging: an emerging link.

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All Publications

2013: Philipp Gut; Eric Verdin
Rejuvenating SIRT1 Activators.
Cell metabolism 2013;17(5):635-7.
2013: Matthew J Rardin; Birgit Schilling; Dylan J Sorensen; Eric Verdin; Jason M Held; C Ronald Kahn; Biao Li; Sean D Mooney; John C Newman; Michael P Cusack; Bradford W Gibson
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(16):6601-6.
2013: Philip I Merksamer; Danica Chen; Wenjuan He; Matthew David Hirschey; Yufei Liu; Eric Verdin
The sirtuins, oxidative stress and aging: an emerging link.
Aging 2013;5(3):144-50.
2013: Daniela Boehm; James E Bradner; Vincenzo Calvanese; Roy D Dar; Pao-Chen Li; Laura Martins; Vicente Planelles; Sebastian Schroeder; Robert Siliciano; Eric Verdin; Leor Weinberger; Sifei Xing; Ming-Ming Zhou; Katherine Aull; Melanie Ott
BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.
Cell cycle (Georgetown, Tex.) 2013;12(3):452-62.
2013: Philipp Gut; Laura Hasenkamp; Daniel Hesselson; Matthew David Hirschey; Joseph Hsiao; Katerina Akassoglou; Olov Andersson; Bernat Baeza-Raja; Eric Verdin; Didier Y R Stainier
Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.
Nature chemical biology 2013;9(2):97-104.
2013: Tadahiro Shimazu; Kotaro Shirakawa; Robert D Stevens; Scott Ulrich; Katerina Akassoglou; Rafael de Cabo; Robert V Farese; Carrie A Grueter; Wenjuan He; Matthew David Hirschey; Natacha Le Moan; Hyungwook Lim; Christopher B Newgard; John Newman; Laura R Saunders; Eric Verdin
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.
Science (New York, N.Y.) 2013;339(6116):211-4.
2012: Herbert G Kasler; Intelly S Lee; Hyung W Lim; Denis Mottet; Amy M Collins; Eric Verdin
Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.
The EMBO journal 2012;31(23):4453-65.
2012: Wenjuan He; Linh Ho; John C Newman; Margaret Z Wang; Eric Verdin
Mitochondrial sirtuins: regulators of protein acylation and metabolism.
Trends in endocrinology and metabolism: TEM 2012;23(9):467-76.
2012: Steven G Deeks; Eric Verdin; Joseph M McCune
Immunosenescence and HIV.
Current opinion in immunology 2012;24(4):501-6.
2012: Birgit Schilling; Dylan J Sorensen; Eric Verdin; Christine C Wu; Anna M Zawadzka; Michael S Bereman; Michael P Cusack; Barbara E Frewen; Enxuan Jing; C Ronald Kahn; Michael J Maccoss; Brendan X MacLean; Matthew J Rardin; Bradford W Gibson
Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation.
Molecular & cellular proteomics : MCP 2012;11(5):202-14.
2012: Shweta Hakre; Kotaro Shirakawa; Leonard Chavez; Eric Verdin
HIV latency: experimental systems and molecular models.
FEMS microbiology reviews 2012;36(3):706-16.
2012: Hye-Sook Kwon; Hyung W Lim; Martina Schnölzer; Eric Verdin; Jessica Wu; Melanie Ott
Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(6):2712-21.
2012: Yong Pan; Yuya Nishida; Margaret Wang; Eric Verdin
Metabolic regulation, mitochondria and the life-prolonging effect of rapamycin: a mini-review.
Gerontology 2012;58(6):524-30.
2012: Ryan S Streeper; Eric Verdin; Ping Zhou; Sylvaine Cases; Carrie A Grueter; Matthew David Hirschey; Suneil K Koliwad; Malin C Levin; Nathan Salomonis; Robert V Farese
Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice.
Aging 2012;4(1):13-27.
2011: Haleh Rafati; Eric Verdin; Shweta Hakre; Yuri Moshkin; Maribel Parra; Tokameh Mahmoudi
Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency.
PLoS biology 2011;9(11):e1001206.
2011: Matthew David Hirschey; Enxuan Jing; C Ronald Kahn; Sanjay Kakar; Johanna Kuusisto; Markku Laakso; Maggie M Lam; Michael J Muehlbauer; Christopher B Newgard; Bjoern Schwer; Tadahiro Shimazu; Alena Stančáková; Robert D Stevens; Frederick W Alt; Bradley Aouizerat; Nathan M Bass; Amy M Collins; Robert V Farese; Eric Goetzman; Carrie A Grueter; Eric Verdin
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.
Molecular cell 2011;44(2):177-90.
2011: Matthew David Hirschey; Katherine S Pollard; Tadahiro Shimazu; John A Capra; Eric Verdin
SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.
Aging 2011;3(6):635-42.
2011: Hyungwook Lim; Bryan D Young; Denis Mottet; Hyung W Lim; Amy M Collins; Eric N Olson; Eric Verdin
Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(8):4782-93.
2011: Matthew David Hirschey; J-Y Huang; Bjoern Schwer; T Shimazu; Eric Verdin
SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism.
Cold Spring Harbor symposia on quantitative biology 2011;76():267-77.
2011: Shweta Hakre; Leonard Chavez; Kotaro Shirakawa; Eric Verdin
Epigenetic regulation of HIV latency.
Current opinion in HIV and AIDS 2011;6(1):19-24.
2011: Leonard Chávez; Steven Kauder; Eric Verdin
In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus.
Methods (San Diego, Calif.) 2011;53(1):47-53.
2010: Xiaolei Qiu; Katharine Brown; Matthew David Hirschey; Eric Verdin; Danica Chen
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation.
Cell metabolism 2010;12(6):662-7.
2010: Tadahiro Shimazu; Matthew David Hirschey; Lan Hua; Kristin E Dittenhafer-Reed; Bjoern Schwer; David Lombard; Yu Li; Jakob Bunkenborg; Frederick W Alt; John M Denu; Matthew P Jacobson; Eric Verdin
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production.
Cell metabolism 2010;12(6):654-61.
2010: Eric Verdin; Matthew David Hirschey; Lydia W S Finley; Marcia C Haigis
Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling.
Trends in biochemical sciences 2010;35(12):669-75.
2010: Jing-Yi Huang; Matthew David Hirschey; Tadahiro Shimazu; Linh Ho; Eric Verdin
Mitochondrial sirtuins.
Biochimica et biophysica acta 2010;1804(8):1645-51.
2010: Laura R Saunders; Amar Deep Sharma; Jaime Tawney; Masato Nakagawa; Keisuke Okita; Shinya Yamanaka; Holger Willenbring; Eric Verdin
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues.
Aging 2010;2(7):415-31.
2010: Tadahiro Shimazu; Matthew David Hirschey; Jing-Yi Huang; Linh T Y Ho; Eric Verdin
Acetate metabolism and aging: An emerging connection.
Mechanisms of ageing and development 2010;131(7-8):511-6.
2010: Melanie Ott; Eric Verdin
HAT trick: p300, small molecule, inhibitor.
Chemistry & biology 2010;17(5):417-8.
2010: Sara Pagans; Steven E Kauder; Katrin Kaehlcke; Naoki Sakane; Sebastian Schroeder; Wilma Dormeyer; Raymond C Trievel; Eric Verdin; Martina Schnolzer; Melanie Ott
The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.
Cell host & microbe 2010;7(3):234-44.
2010: Matthew David Hirschey; Tadahiro Shimazu; Eric Goetzman; Enxuan Jing; Bjoern Schwer; David Lombard; Carrie A Grueter; Charles Harris; Sudha Biddinger; Olga R Ilkayeva; Robert D Stevens; Yu Li; Asish K Saha; Neil B Ruderman; James R Bain; Christopher B Newgard; Robert V Farese; Frederick W Alt; C Ronald Kahn; Eric Verdin
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Nature 2010;464(7285):121-5.
2009: Jana Blazkova; Katerina Trejbalova; Françoise Gondois-Rey; Philippe Halfon; Patrick Philibert; Allan Guiguen; Eric Verdin; Daniel Olive; Carine Van Lint; Jiri Hejnar; Ivan Hirsch
CpG methylation controls reactivation of HIV from latency.
PLoS pathogens 2009;5(8):e1000554.
2009: Steven E Kauder; Alberto Bosque; Annica Lindqvist; Vicente Planelles; Eric Verdin
Epigenetic regulation of HIV-1 latency by cytosine methylation.
PLoS pathogens 2009;5(6):e1000495.
2009: Laura R Saunders; Eric Verdin
Cell biology. Stress response and aging.
Science (New York, N.Y.) 2009;323(5917):1021-2.
2009: Stefan Schäfer; Laura Saunders; Sonja Schlimme; Vassil Valkov; Julia M Wagner; Felix Kratz; Wolfgang Sippl; Eric Verdin; Manfred Jung
Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors.
ChemMedChem 2009;4(2):283-90.
2009: D Mottet; S Pirotte; V Lamour; Martin Hagedorn; Sophie JAVERZAT; A Bikfalvi; Akeila Bellahcène; Eric Verdin; Vincent Castronovo
HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism.
Oncogene 2009;28(2):243-56.
2008: Gary K Scott; Corina Marx; Crystal E Berger; Laura R Saunders; Eric Verdin; Stefan Schäfer; Manfred Jung; Christopher C Benz
Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6.
Molecular cancer research : MCR 2008;6(7):1250-8.
2008: Shusheng Wang; Xiumin Li; Maribel Parra; Eric Verdin; Rhonda Bassel-Duby; Eric N Olson
Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7738-43.
2008: Robert C Neugebauer; Urszula Uchiechowska; Rene Meier; Henning Hruby; Vassil Valkov; Eric Verdin; Wolfgang Sippl; Manfred Jung
Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode.
Journal of medicinal chemistry 2008;51(5):1203-13.
2008: Stefan Schäfer; Laura Saunders; Elena Eliseeva; Alfredo Velena; Mira Jung; Andreas Schwienhorst; Anja Strasser; Achim Dickmanns; Ralf Ficner; Sonja Schlimme; Wolfgang Sippl; Eric Verdin; Manfred Jung
Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs).
Bioorganic & medicinal chemistry 2008;16(4):2011-33.
2008: Bjoern Schwer; Eric Verdin
Conserved metabolic regulatory functions of sirtuins.
Cell metabolism 2008;7(2):104-12.
2008: Eric Verdin
Regulation of human immunodeficiency virus-1 latency and its reactivation.
Bulletin et mémoires de l'Académie royale de médecine de Belgique 2008;163(6):355-64; discussion 364-5.
2007: David Lombard; Frederick W Alt; Hwei-Ling Cheng; Jakob Bunkenborg; Ryan S Streeper; Raul Mostoslavsky; Jennifer Kim; George D Yancopoulos; David M Valenzuela; Andrew Murphy; Yinhua Yang; Yaohui Chen; Matthew David Hirschey; Roderick T Bronson; Marcia Haigis; Leonard Guarente; Robert V Farese; Sherman Weissman; Eric Verdin; Bjoern Schwer
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Molecular and cellular biology 2007;27(24):8807-14.
2007: Nidhi Ahuja; Bjoern Schwer; stefania carobbio; David Waltregny; Brian J North; Vincent Castronovo; Pierre Maechler; Eric Verdin
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase.
The Journal of biological chemistry 2007;282(46):33583-92.
2007: Eric Verdin
AROuSing SIRT1: identification of a novel endogenous SIRT1 activator.
Molecular cell 2007;28(3):354-6.
2007: Dwayne Bisgrove; Tokameh Mahmoudi; Peter Henklein; Eric Verdin
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13690-5.
2007: L R Saunders; Eric Verdin
Sirtuins: critical regulators at the crossroads between cancer and aging.
Oncogene 2007;26(37):5489-504.
2007: Brian J North; Eric Verdin
Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation.
The Journal of biological chemistry 2007;282(27):19546-55.
2007: Herbert G Kasler; Eric Verdin
Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes.
Molecular and cellular biology 2007;27(14):5184-200.
2007: Keris Krennhrubec; Brett L Marshall; Mark Hedglin; Eric Verdin; Scott M Ulrich
Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(10):2874-8.
2007: Maribel Parra; Tokameh Mahmoudi; Eric Verdin
Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes.
Genes & development 2007;21(6):638-43.
2007: Brian J North; Eric Verdin
Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis.
PloS one 2007;2(8):e784.
2006: Laura R Saunders; Eric Verdin
Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors.
Molecular cancer therapeutics 2006;5(11):2777-85.
2006: Tokameh Mahmoudi; Maribel Parra; Robert G J Vries; Steven E Kauder; C Peter Verrijzer; Melanie Ott; Eric Verdin
The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter.
The Journal of biological chemistry 2006;281(29):19960-8.
2006: Bjoern Schwer; Jakob Bunkenborg; Regis O Verdin; Jens S Andersen; Eric Verdin
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10224-9.
2006: Samuel Williams; Lin Feng Chen; Hakju Kwon; Carmen M Ruiz-Jarabo; Eric Verdin; Warner Greene
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation.
The EMBO journal 2006;25(1):139-49.
2005: Andrew J Olaharski; Jasper Rine; Brett L Marshall; Joshua Babiarz; Luoping Zhang; Eric Verdin; Martyn T Smith
The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases.
PLoS genetics 2005;1(6):e77.
2005: Dwayne Bisgrove; Mary K Lewinski; Frederic D Bushman; Eric Verdin
Molecular mechanisms of HIV-1 proviral latency.
Expert review of anti-infective therapy 2005;3(5):805-14.
2005: Brian J North; Bjoern Schwer; Nidhi Ahuja; Brett Marshall; Eric Verdin
Preparation of enzymatically active recombinant class III protein deacetylases.
Methods (San Diego, Calif.) 2005;36(4):338-45.
2005: Sybille Wittich; Hans Scherf; Changping Xie; Birgit Heltweg; Franck Dequiedt; Eric Verdin; Clarissa Gerhäuser; Manfred Jung
Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines.
Anti-cancer drugs 2005;16(6):635-43.
2005: Mary K Lewinski; Dwayne Bisgrove; Paul Shinn; Huaming Chen; Christian Hoffmann; Sridhar Hannenhalli; Eric Verdin; Charles C Berry; SD MA; Frederic D Bushman
Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.
Journal of virology 2005;79(11):6610-9.
2005: David Waltregny; Wendy Glénisson; Siv Ly Tran; Brian J North; Eric Verdin; Alain Colige; Vincent Castronovo
Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(8):966-8.
2005: Maribel Parra; Herbert G Kasler; Timothy A McKinsey; Eric N Olson; Eric Verdin
Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation.
The Journal of biological chemistry 2005;280(14):13762-70.
2005: Prerana Jayakumar; Irina Berger; Frank Autschbach; Mark Weinstein; Benjamin Funke; Eric Verdin; Mark A Goldsmith; Oliver T Keppler
Tissue-resident macrophages are productively infected ex vivo by primary X4 isolates of human immunodeficiency virus type 1.
Journal of virology 2005;79(8):5220-6.
2005: Sara Pagans; Angelika Pedal; Brian J North; Katrin Kaehlcke; Brett L Marshall; Alexander Dorr; Claudia Hetzer-Egger; Peter Henklein; Roy Frye; Michael W McBurney; Henning Hruby; Manfred Jung; Eric Verdin; Melanie Ott
SIRT1 regulates HIV transcription via Tat deacetylation.
PLoS biology 2005;3(2):e41.
2004: Birgit Heltweg; Franck Dequiedt; Brett L Marshall; Carsten Brauch; Minoru Yoshida; Norikazu Nishino; Eric Verdin; Manfred Jung
Subtype selective substrates for histone deacetylases.
Journal of medicinal chemistry 2004;47(21):5235-43.
2004: Samuel Williams; Lin Feng Chen; Hakju Kwon; David Fenard; Dwayne Bisgrove; Eric Verdin; Warner Greene
Prostratin antagonizes HIV latency by activating NF-kappaB.
The Journal of biological chemistry 2004;279(40):42008-17.
2004: David Waltregny; Laurence de Leval; Wendy Glénisson; Siv Ly Tran; Brian J North; Akeila Bellahcène; Ulrich Weidle; Eric Verdin; Vincent Castronovo
Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues.
The American journal of pathology 2004;165(2):553-64.
2004: David Waltregny; Brian J North; F Van Mellaert; Jean de Leval; Eric Verdin; Vincent Castronovo
Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells.
European journal of histochemistry : EJH 2004;48(3):273-90.
2004: Melanie Ott; Alexander Dorr; Claudia Hetzer-Egger; Katrin Kaehlcke; Martina Schnolzer; Peter Henklein; Philip A Cole; Ming-Ming Zhou; Eric Verdin
Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation.
Novartis Foundation symposium 2004;259():182-93; discussion 193-6, 223-5.
2004: Eric Verdin; Franck Dequiedt; Herbert G Kasler
HDAC7 regulates apoptosis in developing thymocytes.
Novartis Foundation symposium 2004;259():115-29; discussion 129-31, 163-9.
2004: Brian J North; Eric Verdin
Sirtuins: Sir2-related NAD-dependent protein deacetylases.
Genome biology 2004;5(5):224.
2004: Eric Verdin; Franck Dequiedt; Wolfgang Fischle; Roy Frye; Brett Marshall; Brian J North
Measurement of mammalian histone deacetylase activity.
Methods in enzymology 2004;377():180-96.
2003: Birgit Heltweg; Franck Dequiedt; Eric Verdin; Manfred Jung
Nonisotopic substrate for assaying both human zinc and NAD+-dependent histone deacetylases.
Analytical biochemistry 2003;319(1):42-8.
2003: Katrin Kaehlcke; Alexander Dorr; Claudia Hetzer-Egger; veronique kiermer; Peter Henklein; Martina Schnoelzer; Erwann P Loret; Philip A Cole; Eric Verdin; Melanie Ott
Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation.
Molecular cell 2003;12(1):167-76.
2003: Jean-Luc Danet; Xavier Foissac; Leyla Zreik; Pascal Salar; Eric Verdin; Jean-Georges Nourrisseau; Monique Garnier
"Candidatus Phlomobacter fragariae" Is the Prevalent Agent of Marginal Chlorosis of Strawberry in French Production Fields and Is Transmitted by the Planthopper Cixius wagneri (China).
Phytopathology 2003;93(6):644-9.
2003: Franck Dequiedt; Herbert G Kasler; Wolfgang Fischle; veronique kiermer; Marc Weinstein; Brian G Herndier; Eric Verdin
HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis.
Immunity 2003;18(5):687-98.
2003: Eric Verdin; Franck Dequiedt; Herbert G Kasler
Class II histone deacetylases: versatile regulators.
Trends in genetics : TIG 2003;19(5):286-93.
2003: albert jordan; Dwayne Bisgrove; Eric Verdin
HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.
The EMBO journal 2003;22(8):1868-77.
2003: Marjorie Pion; albert jordan; Angelique Biancotto; Franck Dequiedt; Françoise Gondois-Rey; Sophie Rondeau; Robert Vigne; Jiri Hejnar; Eric Verdin; Ivan Hirsch
Transcriptional suppression of in vitro-integrated human immunodeficiency virus type 1 does not correlate with proviral DNA methylation.
Journal of virology 2003;77(7):4025-32.
2003: Brian J North; Brett L Marshall; Margie T Borra; John M Denu; Eric Verdin
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.
Molecular cell 2003;11(2):437-44.
2002: Bjoern Schwer; Brian J North; Roy A Frye; Melanie Ott; Eric Verdin
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase.
The Journal of cell biology 2002;158(4):647-57.
2002: Alexander Dorr; veronique kiermer; Angelika Pedal; Hans-Richard Rackwitz; Peter Henklein; Ulrich Schubert; Ming-Ming Zhou; Eric Verdin; Melanie Ott
Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain.
The EMBO journal 2002;21(11):2715-23.
2002: Margie T Borra; Forest J O'Neill; Michael D Jackson; Brett Marshall; Eric Verdin; Kathy R Foltz; John M Denu
Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases.
The Journal of biological chemistry 2002;277(15):12632-41.
2002: Jane C Murphy; Wolfgang Fischle; Eric Verdin; John H Sinclair
Control of cytomegalovirus lytic gene expression by histone acetylation.
The EMBO journal 2002;21(5):1112-20.
2002: Christophe Deroanne; Karine Bonjean; Sandrine Servotte; Laetitia Devy; Alain Colige; Nathalie Clausse; Silvia Blacher; Eric Verdin; Jean-Michel Foidart; Betty Nusgens; Vincent Castronovo
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling.
Oncogene 2002;21(3):427-36.
2002: Wolfgang Fischle; Franck Dequiedt; Michael Hendzel; Matthew G Guenther; Mitchell Lazar; Wolfgang Voelter; Eric Verdin
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR.
Molecular cell 2002;9(1):45-57.
2001: Michael J Kruhlak; Michael Hendzel; Wolfgang Fischle; Nicholas Bertos; S Hameed; Xiang-Jiao Yang; Eric Verdin; David P Bazett-Jones
Regulation of global acetylation in mitosis through loss of histone acetyltransferases and deacetylases from chromatin.
The Journal of biological chemistry 2001;276(41):38307-19.
2001: Wolfgang Fischle; Franck Dequiedt; M Fillion; Michael Hendzel; Wolfgang Voelter; Eric Verdin
Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.
The Journal of biological chemistry 2001;276(38):35826-35.
2001: Wolfgang Fischle; Eric Verdin; Warner Greene
Duration of nuclear NF-kappaB action regulated by reversible acetylation.
Science (New York, N.Y.) 2001;293(5535):1653-7.
2001: albert jordan; P Defechereux; Eric Verdin
The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation.
The EMBO journal 2001;20(7):1726-38.
2001: Wolfgang Fischle; veronique kiermer; Franck Dequiedt; Eric Verdin
The emerging role of class II histone deacetylases.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2001;79(3):337-48.
2000: K D Huynh; Wolfgang Fischle; Eric Verdin; Vivian J Bardwell
BCoR, a novel corepressor involved in BCL-6 repression.
Genes & development 2000;14(14):1810-23.
2000: Michael J Kruhlak; M A Lever; Wolfgang Fischle; Eric Verdin; David P Bazett-Jones; Michael Hendzel
Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments.
The Journal of cell biology 2000;150(1):41-51.
2000: Matthew G Guenther; William Stratton Lane; Wolfgang Fischle; Eric Verdin; Mitchell Lazar; Ramin Shiekhattar
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness.
Genes & development 2000;14(9):1048-57.
1999: Melanie Ott; Martina Schnölzer; J Garnica; Wolfgang Fischle; S Emiliani; Hans-Richard Rackwitz; Eric Verdin
Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity.
Current biology : CB 1999;9(24):1489-92.
1999: Wolfgang Fischle; S Emiliani; Michael Hendzel; T Nagase; N Nomura; Wolfgang Voelter; Eric Verdin
A new family of human histone deacetylases related to Saccharomyces cerevisiae HDA1p.
The Journal of biological chemistry 1999;274(17):11713-20.
1999: Ulrich Mahlknecht; S Emiliani; V Najfeld; S Young; Eric Verdin
Genomic organization and chromosomal localization of the human histone deacetylase 3 gene.
Genomics 1999;56(2):197-202.
1999: Ulrich Mahlknecht; Richard Bucala; D Hoelzer; Eric Verdin
High resolution physical mapping of human HDAC3, a potential tumor suppressor gene in the 5q31 region.
Cytogenetics and cell genetics 1999;86(3-4):237-9.
1999: Ulrich Mahlknecht; R Bucala; Eric Verdin
Assignment of the histone deacetylase gene (Hdac3) to mouse chromosome 18B3 by in situ hybridization.
Cytogenetics and cell genetics 1999;84(3-4):192-3.
1998: Georges Herbein; Ulrich Mahlknecht; F Batliwalla; P Gregersen; T Pappas; J Butler; William A O'Brien; Eric Verdin
Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.
Nature 1998;395(6698):189-94.
1998: veronique kiermer; Carine Van Lint; D Briclet; Caroline Vanhulle; Richard Kettmann; Eric Verdin; Arsène Burny; Louis Droogmans
An interferon regulatory factor binding site in the U5 region of the bovine leukemia virus long terminal repeat stimulates Tax-independent gene expression.
Journal of virology 1998;72(7):5526-34.
1998: S Emiliani; Wolfgang Fischle; Carine Van Lint; Y Al-Abed; Eric Verdin
Characterization of a human RPD3 ortholog, HDAC3.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):2795-800.
1998: M Ott; JL Lovett; L Mueller; Eric Verdin
Superinduction of IL-8 in T cells by HIV-1 Tat protein is mediated through NF-kappaB factors.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2872-80.
1998: S Emiliani; Wolfgang Fischle; M Ott; Carine Van Lint; C A Amella; Eric Verdin
Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line.
Journal of virology 1998;72(2):1666-70.
1998: Georges Herbein; Carine Van Lint; JL Lovett; Eric Verdin
Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes.
Journal of virology 1998;72(1):660-70.
1997: Carine Van Lint; C A Amella; S Emiliani; M John; T Jie; Eric Verdin
Transcription factor binding sites downstream of the human immunodeficiency virus type 1 transcription start site are important for virus infectivity.
Journal of virology 1997;71(8):6113-27.
1997: M Ott; S Emiliani; Carine Van Lint; Georges Herbein; JL Lovett; Narendra Chirmule; Thomas W McCloskey; Savita Pahwa; Eric Verdin
Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway.
Science (New York, N.Y.) 1997;275(5305):1481-5.
1997: Thomas W McCloskey; M Ott; E Tribble; S A Khan; Saul Teichberg; M O Paul; Savita Pahwa; Eric Verdin; Narendra Chirmule
Dual role of HIV Tat in regulation of apoptosis in T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):1014-9.
1996: S Emiliani; Carine Van Lint; Wolfgang Fischle; P Paras; M Ott; J Brady; Eric Verdin
A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6377-81.
1996: Carine Van Lint; S Emiliani; M Ott; Eric Verdin
Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.
The EMBO journal 1996;15(5):1112-20.
1996: Carine Van Lint; S Emiliani; Eric Verdin
The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.
Gene expression 1996;5(4-5):245-53.
1995: Eric Verdin; Carine Van Lint
Internal transcriptional regulatory elements in HIV-1 and other retroviruses.
Cellular and molecular biology (Noisy-le-Grand, France) 1995;41(3):365-9.
1994: A el Kharroubi; Eric Verdin
Protein-DNA interactions within DNase I-hypersensitive sites located downstream of the HIV-1 promoter.
The Journal of biological chemistry 1994;269(31):19916-24.
1994: Carine Van Lint; J Ghysdael; P Paras; Arsène Burny; Eric Verdin
A transcriptional regulatory element is associated with a nuclease-hypersensitive site in the pol gene of human immunodeficiency virus type 1.
Journal of virology 1994;68(4):2632-48.
1993: Eric Verdin; P Paras; Carine Van Lint
Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation.
The EMBO journal 1993;12(8):3249-59.
1992: Norman E Sharpless; D Gilbert; B Vandercam; J M Zhou; Eric Verdin; Gabriele V Ronnett; E Friedman; Monique Dubois-Dalcq
The restricted nature of HIV-1 tropism for cultured neural cells.
Virology 1992;191(2):813-25.
1992: Norman E Sharpless; William A O'Brien; Eric Verdin; Conrad Kufta; I S Chen; Monique Dubois-Dalcq
Human immunodeficiency virus type 1 tropism for brain microglial cells is determined by a region of the env glycoprotein that also controls macrophage tropism.
Journal of virology 1992;66(4):2588-93.
1991: Carine Van Lint; Arsène Burny; Eric Verdin
The intragenic enhancer of human immunodeficiency virus type 1 contains functional AP-1 binding sites.
Journal of virology 1991;65(12):7066-72.
1991: Eric Verdin
DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency virus type 1.
Journal of virology 1991;65(12):6790-9.
1990: Eric Verdin; N Becker; Françoise Bex; Louis Droogmans; Arsène Burny
Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4874-8.
1989: Martine Delchambre; D Gheysen; D Thines; C Thiriart; E Jacobs; Eric Verdin; M Horth; Arsène Burny; Françoise Bex
The GAG precursor of simian immunodeficiency virus assembles into virus-like particles.
The EMBO journal 1989;8(9):2653-60.
1988: Arsène Burny; Françoise Bex; R Brasseur; M C Khim; Martine Delchambre; M Horth; Eric Verdin
Human immunodeficiency virus cell entry: new insights into the fusion mechanism.
Journal of acquired immune deficiency syndromes 1988;1(6):579-82.