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Hal Broxmeyer

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
87
Cooper, Scott
71
Lu, L
64
Hangoc, Giao
47
Mantel, Charlie
19
Kim, Young-June
16
Kim, Chang
15
Hromas, Robert
15
Li, ZH
13
Kwon, Byoung
11
Braun, SE
10
Clapp, Wade
10
Lee, Younghee
10
Ge, Y
10
Pelus, Louis
9
Ritchie, A

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Publications

TOP 3
Campbell Timothy B; Basu Sunanda; Hangoc Giao; Tao Wen; Broxmeyer Hal E
Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation.
Stumpo Deborah J; Broxmeyer Hal E; Ward Toni; Cooper Scott; Hangoc Giao; Chung Yang Jo; Shelley William C; Richfield Eric K; Ray Manas K; Yoder Mervin C; Aplan Peter D; Blackshear Perry J
Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis.
Strack Rita L; Strongin Daniel E; Bhattacharyya Dibyendu; Tao Wen; Berman Allison; Broxmeyer Hal E; Keenan Robert J; Glick Benjamin S
A noncytotoxic DsRed variant for whole-cell labeling.

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All Publications

2009: Campbell Timothy B; Basu Sunanda; Hangoc Giao; Tao Wen; Broxmeyer Hal E
Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation.
Blood 2009;114(16):3392-401.
2009: Stumpo Deborah J; Broxmeyer Hal E; Ward Toni; Cooper Scott; Hangoc Giao; Chung Yang Jo; Shelley William C; Richfield Eric K; Ray Manas K; Yoder Mervin C; Aplan Peter D; Blackshear Perry J
Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis.
Blood 2009;114(12):2401-10.
2008: Strack Rita L; Strongin Daniel E; Bhattacharyya Dibyendu; Tao Wen; Berman Allison; Broxmeyer Hal E; Keenan Robert J; Glick Benjamin S
A noncytotoxic DsRed variant for whole-cell labeling.
Nature methods 2008;5(11):955-7.
2008: Rohrabaugh Sara; Mantel Charlie; Broxmeyer Hal E
Mouse hematopoietic stem cells, unlike human and mouse embryonic stem cells, exhibit checkpoint-apoptosis coupling.
Stem cells and development 2008;17(5):1017-20.
2008: Mantel Charlie R; Wang Rui-Hong; Deng Chuxia; Broxmeyer Hal E
Sirt1, notch and stem cell "age asymmetry".
Cell cycle (Georgetown, Tex.) 2008;7(18):2821-5.
2008: Pulliam Anna C; Hobson M Joe; Ciccone Samantha L; Li Yan; Chen Shi; Srour Edward F; Yang Feng-Chun; Broxmeyer Hal E; Clapp D Wade
AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice.
Experimental hematology 2008;36(9):1084-90.
2008: Liu Ying; Hangoc Giao; Campbell Timothy B; Goodman Michael; Tao Wen; Pollok Karen; Srour Edward F; Broxmeyer Hal E
Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34(+) NOD/SCID-repopulating cells.
Experimental hematology 2008;36(8):947-56.
2008: Mantel Charlie; Broxmeyer Hal E
Sirtuin 1, stem cells, aging, and stem cell aging.
Current opinion in hematology 2008;15(4):326-31.
2008: Singh Pratibha; Yao Yongxue; Weliver Abigail; Broxmeyer Hal E; Hong Soon-Cheol; Chang Cheong-Hee
Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow.
Stem cells (Dayton, Ohio) 2008;26(4):1009-16.
2008: Han Myung-Kwan; Song Eun-Kyung; Guo Ying; Ou Xuan; Mantel Charlie; Broxmeyer Hal E
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization.
Cell stem cell 2008;2(3):241-51.
2008: Mantel Charlie; Guo Ying; Lee Man Ryul; Han Myung Kwan; Rhorabough Sara; Kim Kye Seong; Broxmeyer Hal E
Cells enter a unique intermediate 4N stage, not 4N-G1, after aborted mitosis.
Cell cycle (Georgetown, Tex.) 2008;7(4):484-92.
2008: Kim Young-June; Han Myung-Kwan; Broxmeyer Hal E
4-1BB regulates NKG2D costimulation in human cord blood CD8+ T cells.
Blood 2008;111(3):1378-86.
2008: Broxmeyer Hal E
Chemokines in hematopoiesis.
Current opinion in hematology 2008;15(1):49-58.
2008: Guo Ying; Mantel Charlie; Hromas Robert A; Broxmeyer Hal E
Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin.
Stem cells (Dayton, Ohio) 2008;26(1):30-4.
2008: Campbell Timothy B; Broxmeyer Hal E
CD26 inhibition and hematopoiesis: a novel approach to enhance transplantation.
Frontiers in bioscience : a journal and virtual library 2008;13():1795-805.
2007: Li Geling; Abediankenari Saeid; Kim Young-June; Campbell Timothy B; Ito Shigeki; Graham-Evans Barbara; Cooper Scott; Broxmeyer Hal E
TGF-beta combined with M-CSF and IL-4 induces generation of immune inhibitory cord blood dendritic cells capable of enhancing cytokine-induced ex vivo expansion of myeloid progenitors.
Blood 2007;110(8):2872-9.
2007: Kang Seung G; Lim Hyung W; Andrisani Ourania M; Broxmeyer Hal E; Kim Chang H
Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(6):3724-33.
2007: Basu Sunanda; Ray Nicole T; Atkinson Simon J; Broxmeyer Hal E
Protein phosphatase 2A plays an important role in stromal cell-derived factor-1/CXC chemokine ligand 12-mediated migration and adhesion of CD34+ cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):3075-85.
2007: Broxmeyer Hal E
Mechanism unknown: prostaglandin E2 may improve HSC therapies.
Cell stem cell 2007;1(2):135-6.
2007: Broxmeyer Hal E; Mejia Jorge Alejandro Henao; Hangoc Giao; Barese Cecilia; Dinauer Mary; Cooper Scott
SDF-1/CXCL12 enhances in vitro replating capacity of murine and human multipotential and macrophage progenitor cells.
Stem cells and development 2007;16(4):589-96.
2007: Broxmeyer Hal E; Sehra Sarita; Cooper Scott; Toney Lisa M; Kusam Saritha; Aloor Jim J; Marchal Christophe C; Dinauer Mary C; Dent Alexander L
Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice.
Molecular and cellular biology 2007;27(15):5275-85.
2007: Altenburg Jeffrey D; Broxmeyer Hal E; Jin Qingwen; Cooper Scott; Basu Sunanda; Alkhatib Ghalib
A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities.
Journal of virology 2007;81(15):8140-8.
2007: Okabe Seiichi; Tauchi Tetsuzo; Nakajima Akihiro; Sashida Goro; Gotoh Akihiko; Broxmeyer Hal E; Ohyashiki Junko H; Ohyashiki Kazuma
Depsipeptide (FK228) preferentially induces apoptosis in BCR/ABL-expressing cell lines and cells from patients with chronic myelogenous leukemia in blast crisis.
Stem cells and development 2007;16(3):503-14.
2007: Campbell Timothy B; Hangoc Giao; Liu Ying; Pollok Karen; Broxmeyer Hal E
Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice.
Stem cells and development 2007;16(3):347-54.
2007: Broxmeyer Hal E; Hangoc Giao; Cooper Scott; Campbell Timothy; Ito Shigeki; Mantel Charlie
AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated by the SDF-1/CXCL12-CXCR4 axis.
Annals of the New York Academy of Sciences 2007;1106():1-19.
2007: Mantel Charlie; Guo Ying; Lee Man Ryul; Kim Min-Kyoung; Han Myung-Kwan; Shibayama Hirohiko; Fukuda Seiji; Yoder Mervin C; Pelus Louis M; Kim Kye-Seong; Broxmeyer Hal E
Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability.
Blood 2007;109(10):4518-27.
2007: Mehta S A; Christopherson K W; Bhat-Nakshatri P; Goulet R J; Broxmeyer H E; Kopelovich L; Nakshatri H
Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion.
Oncogene 2007;26(23):3329-37.
2007: Broxmeyer Hal E; Dent Alexander; Cooper Scott; Hangoc Giao; Wang Zheng-Yu; Du Wenjun; Gervay-Haque Jacquelyn; Sriram Venkataraman; Renukaradhya Gourapura J; Brutkiewicz Randy R
A role for natural killer T cells and CD1d molecules in counteracting suppression of hematopoiesis in mice induced by infection with murine cytomegalovirus.
Experimental hematology 2007;35(4 Suppl 1):87-93.
2007: Broxmeyer Hal E; Li Ji; Hangoc Giao; Cooper Scott; Tao Wen; Mantel Charlie; Graham-Evans Barbara; Ghilardi Nico; de Sauvage Frederic J
Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31.
Experimental hematology 2007;35(4 Suppl 1):78-86.
2007: Li Geling; Basu Sunanda; Han Myung-Kwan; Kim Young-June; Broxmeyer Hal E
Influence of ERK activation on decreased chemotaxis of mature human cord blood monocyte-derived dendritic cells to CCL19 and CXCL12.
Blood 2007;109(8):3173-6.
2007: Tao Wen; Evans Barbara-Graham; Yao Jing; Cooper Scott; Cornetta Kenneth; Ballas Christopher B; Hangoc Giao; Broxmeyer Hal E
Enhanced green fluorescent protein is a nearly ideal long-term expression tracer for hematopoietic stem cells, whereas DsRed-express fluorescent protein is not.
Stem cells (Dayton, Ohio) 2007;25(3):670-8.
2007: Ito Shigeki; Mantel Charlie R; Han Myung-Kwan; Basu Sunanda; Fukuda Seiji; Cooper Scott; Broxmeyer Hal E
Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit in MO7e cells.
Blood 2007;109(5):1923-30.
2007: Mantel Charlie; Broxmeyer Hal E
A new connection between the spindle checkpoint, asymmetric cell division and cytokine signaling.
Cell cycle (Georgetown, Tex.) 2007;6(2):144-6.
2007: Chen Jing; Yu Wen-Mei; Daino Hanako; Broxmeyer Hal E; Druker Brian J; Qu Cheng-Kui
SHP-2 phosphatase is required for hematopoietic cell transformation by Bcr-Abl.
Blood 2007;109(2):778-85.
2006: Broxmeyer Hal E; Cooper Scott; Hangoc Giao; Chang Cheong-Hee
Class II transactivator-mediated regulation of major histocompatibility complex class II antigen expression is important for hematopoietic progenitor cell suppression by chemokines and iron-binding proteins.
Experimental hematology 2006;34(8):1078-84.
2006: Broxmeyer Hal E; Pelus Louis M; Kim Chang H; Hangoc Giao; Cooper Scott; Hromas Robert
Synergistic inhibition in vivo of bone marrow myeloid progenitors by myelosuppressive chemokines and chemokine-accelerated recovery of progenitors after treatment of mice with Ara-C.
Experimental hematology 2006;34(8):1069-77.
2006: Broxmeyer Hal E
Chemokines and chemokine receptors in hematopoiesis and immunology.
Experimental hematology 2006;34(8):965-6.
2006: Broxmeyer Hal E; Starnes Trevor; Ramsey Heather; Cooper Scott; Dahl Richard; Williamson Elizabeth; Hromas Robert
The IL-17 cytokine family members are inhibitors of human hematopoietic progenitor proliferation.
Blood 2006;108(2):770.
2006: Lim Hyung W; Broxmeyer Hal E; Kim Chang H
Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):840-51.
2006: Porecha Nehal K; English Kyle; Hangoc Giao; Broxmeyer Hal E; Christopherson Kent W
Enhanced functional response to CXCL12/SDF-1 through retroviral overexpression of CXCR4 on M07e cells: implications for hematopoietic stem cell transplantation.
Stem cells and development 2006;15(3):325-33.
2006: Broxmeyer Hal E; Ginras Anne-Claude; Sonenberg Nahum; Cooper Scott
Retraction. Macrophage inflammatory protein-1alpha and interferon-inducible protein 10 inhibit synergistically induced growth factor stimulation of MAP kinase activity and suppress phosphorylation of eukaryotic initiation factor 4E and 4E binding protein 1.
Blood 2006;107(12):4713.
2006: Guo Ying; Graham-Evans Barbara; Broxmeyer Hal E
Murine embryonic stem cells secrete cytokines/growth modulators that enhance cell survival/anti-apoptosis and stimulate colony formation of murine hematopoietic progenitor cells.
Stem cells (Dayton, Ohio) 2006;24(4):850-6.
2006: Okabe Seiichi; Tauchi Tetsuzo; Ohyashiki Kazuma; Broxmeyer Hal E
Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45.
Blood cells, molecules & diseases 2006;36(2):308-14.
2006: Broxmeyer Hal E; Srour Edward; Orschell Christie; Ingram David A; Cooper Scott; Plett P Artur; Mead Laura E; Yoder Mervin C
Cord blood stem and progenitor cells.
Methods in enzymology 2006;419():439-73.
2005: Guo Ying; Hangoc Giao; Bian Huimin; Pelus Louis M; Broxmeyer Hal E
SDF-1/CXCL12 enhances survival and chemotaxis of murine embryonic stem cells and production of primitive and definitive hematopoietic progenitor cells.
Stem cells (Dayton, Ohio) 2005;23(9):1324-32.
2005: Basu Sunanda; Broxmeyer Hal E
Transforming growth factor-{beta}1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/CXCL12.
Blood 2005;106(2):485-93.
2005: Zhang Jizhong; Li Geling; Bafica Andre; Pantelic Milica; Zhang Pei; Broxmeyer Hal; Liu Ying; Wetzler Lee; He Johnny J; Chen Tie
Neisseria gonorrhoeae enhances infection of dendritic cells by HIV type 1.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):7995-8002.
2005: Hou Yong-Hao; Srour Edward F; Ramsey Heather; Dahl Richard; Broxmeyer Hal E; Hromas Robert
Identification of a human B-cell/myeloid common progenitor by the absence of CXCR4.
Blood 2005;105(9):3488-92.
2005: Broxmeyer Hal E; Cooper Scott; Hangoc Giao; Kim Chang H
Stromal cell-derived factor-1/CXCL12 selectively counteracts inhibitory effects of myelosuppressive chemokines on hematopoietic progenitor cell proliferation in vitro.
Stem cells and development 2005;14(2):199-203.
2005: Broxmeyer Hal E; Cooper Scott; Lasky Laurence A; De Sauvage Frederic
Identification of a massive reserve of hematopoietic progenitors in mice.
Stem cells and development 2005;14(2):105-10.
2005: Broxmeyer Hal E; Orschell Christie M; Clapp D Wade; Hangoc Giao; Cooper Scott; Plett P Artur; Liles W Conrad; Li Xiaxin; Graham-Evans Barbara; Campbell Timothy B; Calandra Gary; Bridger Gary; Dale David C; Srour Edward F
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist.
The Journal of experimental medicine 2005;201(8):1307-18.
2005: Li Geling; Kim Young-June; Broxmeyer Hal E
Macrophage colony-stimulating factor drives cord blood monocyte differentiation into IL-10(high)IL-12absent dendritic cells with tolerogenic potential.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4706-17.
2005: Fukuda Seiji; Broxmeyer Hal E; Pelus Louis M
Flt3 ligand and the Flt3 receptor regulate hematopoietic cell migration by modulating the SDF-1alpha(CXCL12)/CXCR4 axis.
Blood 2005;105(8):3117-26.
2005: Liles W Conrad; Rodger Elin; Broxmeyer Hal E; Dehner Christine; Badel Karin; Calandra Gary; Christensen Jeff; Wood Brent; Price Thomas H; Dale David C
Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist.
Transfusion 2005;45(3):295-300.
2005: Yu Raymond Yick-Loi; Wang Xing; Pixley Fiona J; Yu J Jessica; Dent Alexander L; Broxmeyer Hal E; Stanley E Richard; Ye B Hilda
BCL-6 negatively regulates macrophage proliferation by suppressing autocrine IL-6 production.
Blood 2005;105(4):1777-84.
2005: Kim Young-June; Stringfield Teresa M; Chen Yan; Broxmeyer Hal E
Modulation of cord blood CD8+ T-cell effector differentiation by TGF-beta1 and 4-1BB costimulation.
Blood 2005;105(1):274-81.
2005: Okabe Seiichi; Fukuda Seiji; Kim Young-June; Niki Masaru; Pelus Louis M; Ohyashiki Kazuma; Pandolfi Pier Paolo; Broxmeyer Hal E
Stromal cell-derived factor-1alpha/CXCL12-induced chemotaxis of T cells involves activation of the RasGAP-associated docking protein p62Dok-1.
Blood 2005;105(2):474-80.
2005: Broxmeyer H E
Biology of cord blood cells and future prospects for enhanced clinical benefit.
Cytotherapy 2005;7(3):209-18.
2004: Parker Graham C; Anastassova-Kristeva Marlene; Broxmeyer Hal E; Dodge William H; Eisenberg Leonard M; Gehling Ursula M; Guenin Louis M; Huss Ralf; Moldovan Nicanor I; Rao Mahendra; Srour Edward F; Yoder Mervin C
Stem cells: shibboleths of development.
Stem cells and development 2004;13(6):579-84.
2004: Joo Eun-Kyoung; Broxmeyer Hal E; Kwon Hyung-Joo; Kang Ho Bum; Kim Jin Sook; Lim Jong Seok; Choe Yong-Kyoung; Choe In Seong; Myung Pyung Keun; Lee Younghee
Enhancement of cell survival by stromal cell-derived factor-1/CXCL12 involves activation of CREB and induction of Mcl-1 and c-Fos in factor-dependent human cell line MO7e.
Stem cells and development 2004;13(5):563-70.
2004: Li Geling; Hangoc Giao; Broxmeyer Hal E
Interleukin-10 in combination with M-CSF and IL-4 contributes to development of the rare population of CD14+CD16++ cells derived from human monocytes.
Biochemical and biophysical research communications 2004;322(2):637-43.
2004: Christopherson Kent W; Hangoc Giao; Mantel Charlie R; Broxmeyer Hal E
Modulation of hematopoietic stem cell homing and engraftment by CD26.
Science (New York, N.Y.) 2004;305(5686):1000-3.
2004: Hübel Kai; Liles W Conrad; Broxmeyer Hal E; Rodger Elin; Wood Brent; Cooper Scott; Hangoc Giao; Macfarland Ron; Bridger Gary J; Henson Geoffrey W; Calandra Gary; Dale David C
Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist.
Supportive cancer therapy 2004;1(3):165-72.
2004: Tao Wen; Wang Mu; Voss Emily D; Cocklin Ross R; Smith Jaime A; Cooper Scott H; Broxmeyer Hal E
Comparative proteomic analysis of human CD34+ stem/progenitor cells and mature CD15+ myeloid cells.
Stem cells (Dayton, Ohio) 2004;22(6):1003-14.
2003: Freie Brian; Li Xiaxin; Ciccone Samantha L M; Nawa Kathy; Cooper Scott; Vogelweid Catherine; Schantz Laurel; Haneline Laura S; Orazi Attilio; Broxmeyer Hal E; Lee Suk-Hee; Clapp D Wade
Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis.
Blood 2003;102(12):4146-52.
2003: Christopherson Kent W; Cooper Scott; Hangoc Giao; Broxmeyer Hal E
CD26 is essential for normal G-CSF-induced progenitor cell mobilization as determined by CD26-/- mice.
Experimental hematology 2003;31(11):1126-34.
2003: Liu Ling; Ding Chunjin; Zeng Wei; Heuer Josef G; Tetreault Jonathan W; Noblitt Timothy W; Hangoc Giao; Cooper Scott; Brune Kellie A; Sharma Ganesh; Fox Niles; Rowlinson Scott W; Rogers Danise P; Witcher Derrick R; Lambooy Peter K; Wroblewski Victor J; Miller James R; Broxmeyer Hal E
Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20.
Blood 2003;102(9):3206-9.
2003: Liles W Conrad; Broxmeyer Hal E; Rodger Elin; Wood Brent; Hübel Kai; Cooper Scott; Hangoc Giao; Bridger Gary J; Henson Geoffrey W; Calandra Gary; Dale David C
Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist.
Blood 2003;102(8):2728-30.
2003: Kaplan Mark H; Chang Hua-Chen; Cooper Scott; Lee Younghee; Broxmeyer Hal E
Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines.
Journal of hematotherapy & stem cell research 2003;12(4):401-8.
2003: Vadhan-Raj Saroj; Patel Shreyaskumar; Bueso-Ramos Carlos; Folloder Jody; Papadopolous Nicholas; Burgess Andrew; Broemeling Lyle D; Broxmeyer Hal E; Benjamin Robert S
Importance of predosing of recombinant human thrombopoietin to reduce chemotherapy-induced early thrombocytopenia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(16):3158-67.
2003: Li Geling; Kim Young-June; Mantel Charlie; Broxmeyer Hal E
P-selectin enhances generation of CD14+CD16+ dendritic-like cells and inhibits macrophage maturation from human peripheral blood monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(2):669-77.
2003: Lee Younghee; Broxmeyer Hal E; Mantel Charlie; Kwon Hyung-Joo; Kim Jae Wha; Kim Jin Sook; Kwon Durhan; Choe In Seong
Synergistic activation of p70S6 kinase associated with stem cell factor in MO7e cells.
Experimental & molecular medicine 2003;35(3):222-6.
2003: Helbig Gregory; Christopherson Kent W; Bhat-Nakshatri Poornima; Kumar Suresh; Kishimoto Hiromitsu; Miller Kathy D; Broxmeyer Hal E; Nakshatri Harikrishna
NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4.
The Journal of biological chemistry 2003;278(24):21631-8.
2003: Christopherson Kent W; Cooper Scott; Broxmeyer Hal E
Cell surface peptidase CD26/DPPIV mediates G-CSF mobilization of mouse progenitor cells.
Blood 2003;101(12):4680-6.
2003: Broxmeyer Hal E; Kohli Lisa; Kim Chang H; Lee Younghee; Mantel Charlie; Cooper Scott; Hangoc Giao; Shaheen Montaser; Li Xiaxin; Clapp D Wade
Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G(alpha)i proteins and enhances engraftment of competitive, repopulating stem cells.
Journal of leukocyte biology 2003;73(5):630-8.
2003: Tao Wen; Hangoc Giao; Hawes John W; Si Yue; Cooper Scott; Broxmeyer Hal E
Profiling of differentially expressed apoptosis-related genes by cDNA arrays in human cord blood CD34+ cells treated with etoposide.
Experimental hematology 2003;31(3):251-60.
2003: Kim Won Y; Broxmeyer Hal E; Han In-Seob; Park Doo H; Lee Ki-Man; Vinay Dass S; Kwon Byoung S
Effect of leukotactin-1 on the protection in vivo of myeloid progenitor cells against cytotoxic chemotherapeutics.
Journal of hematotherapy & stem cell research 2003;12(1):107-13.
2003: Ra Jae S; Broxmeyer Hal E; Kim Myung W; Han In-Seob; Choi Seung W; Kwon Byoung S
Osteoprotegerin inhibits proliferation of myeloid progenitor cells.
Journal of hematotherapy & stem cell research 2003;12(1):33-8.
2003: Haneline Laura S; Li Xiaxin; Ciccone Samantha L M; Hong Ping; Yang Yanzhu; Broxmeyer Hal E; Lee Suk-Hee; Orazi Attilio; Srour Edward F; Clapp D Wade
Retroviral-mediated expression of recombinant Fancc enhances the repopulating ability of Fancc-/- hematopoietic stem cells and decreases the risk of clonal evolution.
Blood 2003;101(4):1299-307.
2003: Broxmeyer Hal E; Srour Edward F; Hangoc Giao; Cooper Scott; Anderson Stacie A; Bodine David M
High-efficiency recovery of functional hematopoietic progenitor and stem cells from human cord blood cryopreserved for 15 years.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(2):645-50.
2003: Broxmeyer Hal E; Cooper Scott; Kohli Lisa; Hangoc Giao; Lee Younghee; Mantel Charlie; Clapp D Wade; Kim Chang H
Transgenic expression of stromal cell-derived factor-1/CXC chemokine ligand 12 enhances myeloid progenitor cell survival/antiapoptosis in vitro in response to growth factor withdrawal and enhances myelopoiesis in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(1):421-9.
2002: Okabe Seiichi; Fukuda Seiji; Broxmeyer Hal E
Src kinase, but not the src kinase family member p56lck, mediates stromal cell-derived factor 1alpha/CXCL12-induced chemotaxis of a T cell line.
Journal of hematotherapy & stem cell research 2002;11(6):923-8.
2002: Kim Young-June; Li Geling; Broxmeyer Hal E
4-1BB ligand stimulation enhances myeloid dendritic cell maturation from human umbilical cord blood CD34+ progenitor cells.
Journal of hematotherapy & stem cell research 2002;11(6):895-903.
2002: Christopherson Kent W; Hangoc Giao; Broxmeyer Hal E
Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(12):7000-8.
2002: Mack David L; Leibowitz David S; Cooper Scott; Ramsey Heather; Broxmeyer Hal E; Hromas Robert
Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development.
Immunology 2002;107(4):444-51.
2002: Kim Young-June; Brutkiewicz Randy R; Broxmeyer Hal E
Role of 4-1BB (CD137) in the functional activation of cord blood CD28(-)CD8(+) T cells.
Blood 2002;100(9):3253-60.
2002: Bacon Kevin; Baggiolini Marco; Broxmeyer Hal; Horuk Richard; Lindley Ivan; Mantovani Alberto; Maysushima Kouji; Murphy Philip; Nomiyama Hisayuki; Oppenheim Joost; Rot Antal; Schall Thomas; Tsang Monica; Thorpe Robin; Van Damme Jo; Wadhwa Meenu; Yoshie Osamu; Zlotnik Albert; Zoon Kathy;
Chemokine/chemokine receptor nomenclature.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2002;22(10):1067-8.
2002: Mantel Charlie R; Gelfano Vasily M; Kim Young-June; McDaniel Andrew; Lee Younghee; Boswell H Scott; Broxmeyer Hal E
P21waf-1-Chk1 pathway monitors G1 phase microtubule integrity and is crucial for restriction point transition.
Cell cycle (Georgetown, Tex.) 2002;1(5):327-36.
2002: Hromas Robert; Cooper Scott; Broxmeyer Hal E
The chemokine CCL21 protects normal marrow progenitors from Ara-C cytotoxicity.
Cancer chemotherapy and pharmacology 2002;50(2):163-6.
2002: Okabe Seiichi; Fukuda Seiji; Broxmeyer Hal E
Activation of Wiskott-Aldrich syndrome protein and its association with other proteins by stromal cell-derived factor-1alpha is associated with cell migration in a T-lymphocyte line.
Experimental hematology 2002;30(7):761-6.
2002: Starnes Trevor; Broxmeyer Hal E; Robertson Michael J; Hromas Robert
Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(2):642-6.
2002: Dai Mu-Shui; Chevallier Nathalie; Stone Stacie; Heinrich Michael C; McConnell Melanie; Reuter Tanja; Broxmeyer Hal E; Licht Jonathan D; Lu Li; Hoatlin Maureen E
The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific.
The Journal of biological chemistry 2002;277(29):26327-34.
2002: Broxmeyer Hal E; Bruns Heather A; Zhang Shangming; Cooper Scott; Hangoc Giao; McKenzie Andrew N J; Dent Alexander L; Schindler Ulrike; Naeger Lisa K; Hoey Timothy; Kaplan Mark H
Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M.
Immunity 2002;16(6):815-25.
2002: Anzai Naoyuki; Lee Younghee; Youn Byung-S; Fukuda Seiji; Kim Young-June; Mantel Charlie; Akashi Makoto; Broxmeyer Hal E
C-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors.
Blood 2002;99(12):4413-21.
2002: Lee Younghee; Gotoh Akihiko; Kwon Hyung-Joo; You Minute; Kohli Lisa; Mantel Charlie; Cooper Scott; Hangoc Giao; Miyazawa Keisuke; Ohyashiki Kazuma; Broxmeyer Hal E
Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines.
Blood 2002;99(12):4307-17.
2002: Kwon Byoung S; Hurtado Jose C; Lee Zang H; Kwack Kyu B; Seo Su K; Choi Beom K; Koller Beverly H; Wolisi Godwin; Broxmeyer Hal E; Vinay Dass S
Immune responses in 4-1BB (CD137)-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(11):5483-90.
2002: Youn B-S; Yu K-Y; Oh J; Lee J; Lee T-H; Broxmeyer H E
Role of the CC chemokine receptor 9/TECK interaction in apoptosis.
Apoptosis : an international journal on programmed cell death 2002;7(3):271-6.
2001: Starnes T; Robertson M J; Sledge G; Kelich S; Nakshatri H; Broxmeyer H E; Hromas R
Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4137-40.
2001: Kim Y J; Broxmeyer H E
Therapeutic potential of 4-1BB (CD137) as a regulator for effector CD8(+) T cells.
Journal of hematotherapy & stem cell research 2001;10(4):441-9.
2001: Youn B S; Kim Y J; Mantel C; Yu K Y; Broxmeyer H E
Blocking of c-FLIP(L)--independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction.
Blood 2001;98(4):925-33.
2001: Broxmeyer H E
Regulation of hematopoiesis by chemokine family members.
International journal of hematology 2001;74(1):9-17.
2001: Broxmeyer H E; Youn B S; Kim C; Hangoc G; Cooper S; Mantel C
Chemokine regulation of hematopoiesis and the involvement of pertussis toxin-sensitive G alpha i proteins.
Annals of the New York Academy of Sciences 2001;938():117-27; discussion 127-8.
2001: Cooper S H; Broxmeyer H E
Measurement of interleukin 3 and other hematopoietic cytokines, such as GM-CSF, G-CSF, M-CSF, erythropoietin, steel factor, and Flt-3 ligand.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2001;Chapter 6():Unit 6.4.
2001: Lee Y; Broxmeyer H E
Synergistic activation of RSK correlates with c-fos induction in MO7e cells stimulated with GM-CSF plus Steel factor.
Biochemical and biophysical research communications 2001;281(4):897-901.
2001: Mantel C R; Braun S E; Lee Y; Kim Y J; Broxmeyer H E
The interphase microtubule damage checkpoint defines an S-phase commitment point and does not require p21(waf-1).
Blood 2001;97(5):1505-7.
2001: Crow M; Taub D D; Cooper S; Broxmeyer H E; Sarris A H
Human recombinant interferon-inducible protein-10: intact disulfide bridges are not required for inhibition of hematopoietic progenitors and chemotaxis of T lymphocytes and monocytes.
Journal of hematotherapy & stem cell research 2001;10(1):147-56.
2001: Lee Y; Mantel C; Anzai N; Braun S E; Broxmeyer H E
Transcriptional and ERK1/2-dependent synergistic upregulation of p21(cip1/waf1) associated with steel factor synergy in MO7e.
Biochemical and biophysical research communications 2001;280(3):675-83.
2001: Mantel C; Hendrie P; Broxmeyer H E
Steel factor regulates cell cycle asymmetry.
Stem cells (Dayton, Ohio) 2001;19(6):483-91.
2000: Lu L; Dai M S; Ge Y; Wang L S; Braun S E; Wait C L; Griffith D J; Heinrich M C; Broxmeyer H E
Co-transduction of cDNAs for c-kit and steel factor into single CD34+ cord blood cells further enhances the growth of erythroid and multipotential progenitors.
Journal of hematotherapy & stem cell research 2000;9(6):813-25.
2000: Dai M S; Mantel C R; Xia Z B; Broxmeyer H E; Lu L
An expansion phase precedes terminal erythroid differentiation of hematopoietic progenitor cells from cord blood in vitro and is associated with up-regulation of cyclin E and cyclin-dependent kinase 2.
Blood 2000;96(12):3985-7.
2000: Xia Z B; Dai M S; Magoulas C; Broxmeyer H E; Lu L
Differentially expressed genes during in vitro differentiation of murine embryonic stem cells transduced with a human erythropoietin receptor cDNA.
Journal of hematotherapy & stem cell research 2000;9(5):651-8.
2000: Lu L; Ge Y; Li Z H; Dai M S; Broxmeyer H E
Enhancement of proliferation and differentiation of erythroid progenitors by co-transduction of erythropoietin receptor and H-ras cDNAS into single CD34(3+) cord blood cells.
Bone marrow transplantation 2000;26(8):817-22.
2000: Zhang S; Broxmeyer H E
Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase.
Biochemical and biophysical research communications 2000;277(1):195-9.
2000: Thomson B G; Robertson K A; Gowan D; Heilman D; Broxmeyer H E; Emanuel D; Kotylo P; Brahmi Z; Smith F O
Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation.
Blood 2000;96(8):2703-11.
2000: Zhang S; Fukuda S; Lee Y; Hangoc G; Cooper S; Spolski R; Leonard W J; Broxmeyer H E
Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling.
The Journal of experimental medicine 2000;192(5):719-28.
2000: Wang L S; Liu H J; Xia Z B; Broxmeyer H E; Lu L
Expression and activation of caspase-3/CPP32 in CD34(+) cord blood cells is linked to apoptosis after growth factor withdrawal.
Experimental hematology 2000;28(8):907-15.
2000: Lu L; Wang L S; Cooper R J; Liu H J; Turner K; Weich N; Broxmeyer H E
Suppressive effects of TNF-alpha, TGF-beta1, and chemokines on megakaryocytic colony formation in CD34+ cells derived from umbilical cord blood compared with mobilized peripheral blood and bone marrow.
Journal of hematotherapy & stem cell research 2000;9(2):195-204.
2000: Braun S E; Chen K; Foster R G; Kim C H; Hromas R; Kaplan M H; Broxmeyer H E; Cornetta K
The CC chemokine CK beta-11/MIP-3 beta/ELC/Exodus 3 mediates tumor rejection of murine breast cancer cells through NK cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(8):4025-31.
2000: Fang S; Steinmetz R; Walker King D; Zeng P; Vogelweid C; Cooper S; Hangcoc G; Broxmeyer H E; Pescovitz O H
Development of a transgenic mouse that overexpresses a novel product of the growth hormone-releasing hormone gene.
Endocrinology 2000;141(4):1377-83.
2000: Dai M S; Heinrich M C; Broxmeyer H E; Lu L
Enhancing effects of co-transduction of both human erythropoietin receptor and c-kit cDNAs into hematopoietic stem/progenitor cells from cord blood on proliferation and differentiation of erythroid progenitors.
Cytokines, cellular & molecular therapy 2000;6(1):1-8.
2000: Wang L S; Liu H J; Broxmeyer H E; Lu L
Interleukin-11 enhancement of VLA-5 mediated adhesion of CD34+ cells from cord blood to fibronectin is associated with the PI-3 kinase pathway.
In vivo (Athens, Greece) 2000;14(2):331-7.
2000: Vadhan-Raj S; Verschraegen C F; Bueso-Ramos C; Broxmeyer H E; Kudelkà A P; Freedman R S; Edwards C L; Gershenson D; Jones D; Ashby M; Kavanagh J J
Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer.
Annals of internal medicine 2000;132(5):364-8.
2000: Xiao M; Luo Z; Mantel C; Broxmeyer H E; Lu L
Transduction of human IL-9 receptor cDNA into TF1 cells induces IL-9 dependency and erythroid differentiation.
Journal of hematotherapy & stem cell research 2000;9(1):77-82.
2000: Hromas R; Cripe L; Hangoc G; Cooper S; Broxmeyer H E
The exodus subfamily of CC chemokines inhibits the proliferation of chronic myelogenous leukemia progenitors.
Blood 2000;95(4):1506-8.
2000: Dai M S; Ge Y; Xia Z B; Broxmeyer H E; Lu L
Introduction of human erythropoietin receptor complementary DNA by retrovirus-mediated gene transfer into murine embryonic stem cells enhances erythropoiesis in developing embryoid bodies.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2000;6(4):395-407.
1999: Jayne J A; Reid S; Braun S E; Broxmeyer H E
Differential in vitro maturation of hematopoietic stem cells from wild-type and immunoglobulin transgenic mice.
Cytokines, cellular & molecular therapy 1999;5(4):195-204.
1999: Kim C H; Hangoc G; Cooper S; Helgason C D; Yew S; Humphries R K; Krystal G; Broxmeyer H E
Altered responsiveness to chemokines due to targeted disruption of SHIP.
The Journal of clinical investigation 1999;104(12):1751-9.
1999: Youn B S; Kim C H; Smith F O; Broxmeyer H E
TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6/CCR9 as a specific receptor.
Blood 1999;94(7):2533-6.
1999: Lu L; Heinrich M C; Wang L S; Dai M S; Zigler A J; Chai L; Broxmeyer H E
Retroviral-mediated gene transduction of c-kit into single hematopoietic progenitor cells from cord blood enhances erythroid colony formation and decreases sensitivity to inhibition by tumor necrosis factor-alpha and transforming growth factor-beta1.
Blood 1999;94(7):2319-32.
1999: Reid S; Broxmeyer H E
The effects of GM-CSF, steel factor and MIP-1alpha on the expression and activation of Cdc25A phosphatase in Mo7e cells.
Cytokines, cellular & molecular therapy 1999;5(3):129-38.
1999: Braun S E; Chen K; Blazar B R; Orchard P J; Sledge G; Robertson M J; Broxmeyer H E; Cornetta K
Flt3 ligand antitumor activity in a murine breast cancer model: a comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action.
Human gene therapy 1999;10(13):2141-51.
1999: Kim C H; Broxmeyer H E
SLC/exodus2/6Ckine/TCA4 induces chemotaxis of hematopoietic progenitor cells: differential activity of ligands of CCR7, CXCR3, or CXCR4 in chemotaxis vs. suppression of progenitor proliferation.
Journal of leukocyte biology 1999;66(3):455-61.
1999: Kim C H; Qu C K; Hangoc G; Cooper S; Anzai N; Feng G S; Broxmeyer H E
Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses.
The Journal of experimental medicine 1999;190(5):681-90.
1999: Ritchie A; Broxmeyer H E
Suppression of p53-mediated growth factor withdrawal-induced apoptosis in the myeloid compartment by hematopoietic cytokines: an overview of hematopoiesis and apoptosis with a presentation of thrombopoietin and the M07E cell line as a model system.
Critical reviews in oncology/hematology 1999;31(3):169-91.
1999: Gotoh A; Reid S; Miyazawa K; Broxmeyer H E
SDF-1 suppresses cytokine-induced adhesion of human haemopoietic progenitor cells to immobilized fibronectin.
British journal of haematology 1999;106(1):171-4.
1999: Broxmeyer H E; Kim C H
Regulation of hematopoiesis in a sea of chemokine family members with a plethora of redundant activities.
Experimental hematology 1999;27(7):1113-23.
1999: Hromas R; Broxmeyer H E; Kim C; Christopherson K; Hou Y H
Isolation of ALP, a novel divergent murine CC chemokine with a unique carboxy terminal extension.
Biochemical and biophysical research communications 1999;258(3):737-40.
1999: Anzai N; Gotoh A; Shibayama H; Broxmeyer H E
Modulation of integrin function in hematopoietic progenitor cells by CD43 engagement: possible involvement of protein tyrosine kinase and phospholipase C-gamma.
Blood 1999;93(10):3317-26.
1999: Kim C H; Pelus L M; Appelbaum E; Johanson K; Anzai N; Broxmeyer H E
CCR7 ligands, SLC/6Ckine/Exodus2/TCA4 and CKbeta-11/MIP-3beta/ELC, are chemoattractants for CD56(+)CD16(-) NK cells and late stage lymphoid progenitors.
Cellular immunology 1999;193(2):226-35.
1999: Mantel C R; Balduini A; Broxmeyer H E
A human factor-dependent cell line simulates cobblestone formation under human bone marrow stromal cells in vitro.
Annals of the New York Academy of Sciences 1999;872():399-401.
1999: Kim C H; Broxmeyer H E
Thrombopoietin and interleukin-3 are chemotactic and chemokinetic chemoattractants for a factor-dependent hematopoietic progenitor cell line.
Annals of the New York Academy of Sciences 1999;872():395-8.
1999: Broxmeyer H E; Kim C H; Cooper S H; Hangoc G; Hromas R; Pelus L M
Effects of CC, CXC, C, and CX3C chemokines on proliferation of myeloid progenitor cells, and insights into SDF-1-induced chemotaxis of progenitors.
Annals of the New York Academy of Sciences 1999;872():142-62; discussion 163.
1999: Zhang S; Mantel C; Broxmeyer H E
Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells.
Journal of leukocyte biology 1999;65(3):372-80.
1999: Shibayama H; Anzai N; Braun S E; Fukuda S; Mantel C; Broxmeyer H E
H-Ras is involved in the inside-out signaling pathway of interleukin-3-induced integrin activation.
Blood 1999;93(5):1540-8.
1999: Reid S; Ritchie A; Boring L; Gosling J; Cooper S; Hangoc G; Charo I F; Broxmeyer H E
Enhanced myeloid progenitor cell cycling and apoptosis in mice lacking the chemokine receptor, CCR2.
Blood 1999;93(5):1524-33.
1999: Wu L W; Reid S; Ritchie A; Broxmeyer H E; Donner D B
The proteasome regulates caspase-dependent and caspase-independent protease cascades during apoptosis of MO7e hematopoietic progenitor cells.
Blood cells, molecules & diseases 1999;25(1):20-9.
1999: Ritchie A; Braun S E; He J; Broxmeyer H E
Thrombopoietin-induced conformational change in p53 lies downstream of the p44/p42 mitogen activated protein kinase cascade in the human growth factor-dependent cell line M07e.
Oncogene 1999;18(7):1465-77.
1999: Hromas R; Broxmeyer H E; Kim C; Nakshatri H; Christopherson K; Azam M; Hou Y H
Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells.
Biochemical and biophysical research communications 1999;255(3):703-6.
1999: Mantel C; Braun S E; Reid S; Henegariu O; Liu L; Hangoc G; Broxmeyer H E
p21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells.
Blood 1999;93(4):1390-8.
1999: Zhang S; Broxmeyer H E
p85 subunit of PI3 kinase does not bind to human Flt3 receptor, but associates with SHP2, SHIP, and a tyrosine-phosphorylated 100-kDa protein in Flt3 ligand-stimulated hematopoietic cells.
Biochemical and biophysical research communications 1999;254(2):440-5.
1999: Kim C H; Broxmeyer H E
Chemokines: signal lamps for trafficking of T and B cells for development and effector function.
Journal of leukocyte biology 1999;65(1):6-15.
1998: Qu C K; Yu W M; Azzarelli B; Cooper S; Broxmeyer H E; Feng G S
Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells.
Molecular and cellular biology 1998;18(10):6075-82.
1998: Kim C H; Pelus L M; White J R; Broxmeyer H E
Macrophage-inflammatory protein-3 beta/EBI1-ligand chemokine/CK beta-11, a CC chemokine, is a chemoattractant with a specificity for macrophage progenitors among myeloid progenitor cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2580-5.
1998: Shibayama H; Anzai N; Ritchie A; Zhang S; Mantel C; Broxmeyer H E
Interleukin-3 and Flt3-ligand induce adhesion of Baf3/Flt3 precursor B-lymphoid cells to fibronectin via activation of VLA-4 and VLA-5.
Cellular immunology 1998;187(1):27-33.
1998: Youn B S; Zhang S; Broxmeyer H E; Antol K; Fraser M J; Hangoc G; Kwon B S
Isolation and characterization of LMC, a novel lymphocyte and monocyte chemoattractant human CC chemokine, with myelosuppressive activity.
Biochemical and biophysical research communications 1998;247(2):217-22.
1998: Braun S E; Mantel C; Rosenthal M; Cooper S; Liu L; Robertson K A; Hromas R; Broxmeyer H E
A positive effect of p21cip1/waf1 in the colony formation from murine myeloid progenitor cells as assessed by retroviral-mediated gene transfer.
Blood cells, molecules & diseases 1998;24(2):138-48.
1998: Ge Y; Li Z H; Marshall M S; Broxmeyer H E; Lu L
Involvement of H-ras in erythroid differentiation of TF1 and human umbilical cord blood CD34 cells.
Blood cells, molecules & diseases 1998;24(2):124-36; discussion 137.
1998: Kim C H; Pelus L M; White J R; Broxmeyer H E
Differential chemotactic behavior of developing T cells in response to thymic chemokines.
Blood 1998;91(12):4434-43.
1998: Haneline L S; Broxmeyer H E; Cooper S; Hangoc G; Carreau M; Buchwald M; Clapp D W
Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice.
Blood 1998;91(11):4092-8.
1998: Youn B S; Zhang S M; Broxmeyer H E; Cooper S; Antol K; Fraser M; Kwon B S
Characterization of CKbeta8 and CKbeta8-1: two alternatively spliced forms of human beta-chemokine, chemoattractants for neutrophils, monocytes, and lymphocytes, and potent agonists at CC chemokine receptor 1.
Blood 1998;91(9):3118-26.
1998: Porcu P; Gaddy J; Broxmeyer H E
Alloantigen-induced unresponsiveness in cord blood T lymphocytes is associated with defective activation of Ras.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4538-43.
1998: Ge Y; Broxmeyer H E; Lu L
Leukemia inhibitory factor and steel factor regulate tie message stability in CD34+ cells from human umbilical cord blood.
In vivo (Athens, Greece) 1998;12(2):149-53.
1998: Broxmeyer H E; Orazi A; Hague N L; Sledge G W; Rasmussen H; Gordon M S
Myeloid progenitor cell proliferation and mobilization effects of BB10010, a genetically engineered variant of human macrophage inflammatory protein-1alpha, in a phase I clinical trial in patients with relapsed/refractory breast cancer.
Blood cells, molecules & diseases 1998;24(1):14-30.
1998: Lu L; Li Z H; He J; Ge Y; Rice S; Broxmeyer H E
Transduction of recombinant human erythropoietin receptor cDNA into daughter progenitors derived from single CD34(3+) cord blood cells changes the differentiation profile of daughter progenitors.
Journal of leukocyte biology 1998;63(3):389-94.
1998: Kim C H; Pelus L M; White J R; Applebaum E; Johanson K; Broxmeyer H E
CK beta-11/macrophage inflammatory protein-3 beta/EBI1-ligand chemokine is an efficacious chemoattractant for T and B cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(5):2418-24.
1998: Kim C H; Broxmeyer H E
In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environment.
Blood 1998;91(1):100-10.
1998: Balduini A; Braun S E; Cornetta K; Lyman S; Broxmeyer H E
Comparative effects of retroviral-mediated gene transfer into primary human stromal cells of Flt3-ligand, interleukin 3 and GM-CSF on production of cord blood progenitor cells in long-term culture.
Stem cells (Dayton, Ohio) 1998;16 Suppl 1():37-49.
1997: Youn B S; Zhang S M; Lee E K; Park D H; Broxmeyer H E; Murphy P M; Locati M; Pease J E; Kim K K; Antol K; Kwon B S
Molecular cloning of leukotactin-1: a novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(11):5201-5.
1997: Ritchie A; Gotoh A; Gaddy J; Braun S E; Broxmeyer H E
Thrombopoietin upregulates the promoter conformation of p53 in a proliferation-independent manner coincident with a decreased expression of Bax: potential mechanisms for survival enhancing effects.
Blood 1997;90(11):4394-402.
1997: Gotoh A; Ritchie A; Takahira H; Broxmeyer H E
Thrombopoietin and erythropoietin activate inside-out signaling of integrin and enhance adhesion to immobilized fibronectin in human growth-factor-dependent hematopoietic cells.
Annals of hematology 1997;75(5-6):207-13.
1997: Boring L; Gosling J; Chensue S W; Kunkel S L; Farese R V; Broxmeyer H E; Charo I F
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.
The Journal of clinical investigation 1997;100(10):2552-61.
1997: Ge Y; Li Z H; Yung Y P; Ratzkin B J; Broxmeyer H E; Lu L
Up-regulation of Tie gene expression by leukemia inhibitory factor and steel factor in CD34+ cells from human umbilical cord blood.
Journal of leukocyte biology 1997;62(4):510-6.
1997: Gaddy J; Broxmeyer H E
Cord blood CD16+56- cells with low lytic activity are possible precursors of mature natural killer cells.
Cellular immunology 1997;180(2):132-42.
1997: Hromas R; Kim C H; Klemsz M; Krathwohl M; Fife K; Cooper S; Schnizlein-Bick C; Broxmeyer H E
Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(6):2554-8.
1997: Krathwohl M D; Hromas R; Brown D R; Broxmeyer H E; Fife K H
Functional characterization of the C---C chemokine-like molecules encoded by molluscum contagiosum virus types 1 and 2.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9875-80.
1997: Chen K; Braun S; Lyman S; Fan Y; Traycoff C M; Wiebke E A; Gaddy J; Sledge G; Broxmeyer H E; Cornetta K
Antitumor activity and immunotherapeutic properties of Flt3-ligand in a murine breast cancer model.
Cancer research 1997;57(16):3511-6.
1997: Gotoh A; Takahira H; Geahlen R L; Broxmeyer H E
Cross-linking of integrins induces tyrosine phosphorylation of the proto-oncogene product Vav and the protein tyrosine kinase Syk in human factor-dependent myeloid cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(6):721-9.
1997: Aronica S M; Gingras A C; Sonenberg N; Cooper S; Hague N; Broxmeyer H E
Macrophage inflammatory protein-1alpha and interferon-inducible protein 10 inhibit synergistically induced growth factor stimulation of MAP kinase activity and suppress phosphorylation of eukaryotic initiation factor 4E and 4E binding protein 1.
Blood 1997;89(10):3582-95.
1997: Vadhan-Raj S; Murray L J; Bueso-Ramos C; Patel S; Reddy S P; Hoots W K; Johnston T; Papadopolous N E; Hittelman W N; Johnston D A; Yang T A; Paton V E; Cohen R L; Hellmann S D; Benjamin R S; Broxmeyer H E
Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer.
Annals of internal medicine 1997;126(9):673-81.
1997: Hromas R; Gray P W; Chantry D; Godiska R; Krathwohl M; Fife K; Bell G I; Takeda J; Aronica S; Gordon M; Cooper S; Broxmeyer H E; Klemsz M J
Cloning and characterization of exodus, a novel beta-chemokine.
Blood 1997;89(9):3315-22.
1997: Tian M; Broxmeyer H E; Fan Y; Lai Z; Zhang S; Aronica S; Cooper S; Bigsby R M; Steinmetz R; Engle S J; Mestek A; Pollock J D; Lehman M N; Jansen H T; Ying M; Stambrook P J; Tischfield J A; Yu L
Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice.
The Journal of experimental medicine 1997;185(8):1517-22.
1997: Takahira H; Gotoh A; Ritchie A; Broxmeyer H E
Steel factor enhances integrin-mediated tyrosine phosphorylation of focal adhesion kinase (pp125FAK) and paxillin.
Blood 1997;89(5):1574-84.
1997: Gotoh A; Broxmeyer H E
The function of BCR/ABL and related proto-oncogenes.
Current opinion in hematology 1997;4(1):3-11.
1997: Broxmeyer H E; Cooper S
High-efficiency recovery of immature haematopoietic progenitor cells with extensive proliferative capacity from human cord blood cryopreserved for 10 years.
Clinical and experimental immunology 1997;107 Suppl 1():45-53.
1997: Braun S E; McIvor R S; Davidson A S; Hanna M; Traycoff C M; Berebetsky D A; Gonin R; Broxmeyer H E; Cornetta K
Retrovirally mediated gene transfer of Arg22 and Tyr22 forms of dihydrofolate reductase into the hematopoietic cell line K562: a comparison of methotrexate resistance.
Cancer gene therapy 1997;4(1):26-32.
1997: Tauchi T; Miyazawa K; Feng G S; Broxmeyer H E; Toyama K
A coiled-coil tetramerization domain of BCR-ABL is essential for the interactions of SH2-containing signal transduction molecules.
The Journal of biological chemistry 1997;272(2):1389-94.
1997: Braun S E; Aronica S M; Ge Y; Takahira H; Etienne-Julan M; Lu L; Minden M D; Lyman S D; Broxmeyer H E
Retroviral mediated gene transfer of Flt3 ligand enhances proliferation and MAP kinase activity of AML5 cells.
Experimental hematology 1997;25(1):51-6.
1997: Broxmeyer H E; Mantel C R; Aronica S M
Biology and mechanisms of action of synergistically stimulated myeloid progenitor cell proliferation and suppression by chemokines.
Stem cells (Dayton, Ohio) 1997;15 Suppl 1():69-77; discussion 78.
1996: Broxmeyer H E; Cooper S; Cacalano G; Hague N L; Bailish E; Moore M W
Involvement of Interleukin (IL) 8 receptor in negative regulation of myeloid progenitor cells in vivo: evidence from mice lacking the murine IL-8 receptor homologue.
The Journal of experimental medicine 1996;184(5):1825-32.
1996: Mantel C; Luo Z; Canfield J; Braun S; Deng C; Broxmeyer H E
Involvement of p21cip-1 and p27kip-1 in the molecular mechanisms of steel factor-induced proliferative synergy in vitro and of p21cip-1 in the maintenance of stem/progenitor cells in vivo.
Blood 1996;88(10):3710-9.
1996: Carver-Moore K; Broxmeyer H E; Luoh S M; Cooper S; Peng J; Burstein S A; Moore M W; de Sauvage F J
Low levels of erythroid and myeloid progenitors in thrombopoietin-and c-mpl-deficient mice.
Blood 1996;88(3):803-8.
1996: Gotoh A; Takahira H; Mantel C; Litz-Jackson S; Boswell H S; Broxmeyer H E
Steel factor induces serine phosphorylation of Stat3 in human growth factor-dependent myeloid cell lines.
Blood 1996;88(1):138-45.
1996: Broxmeyer H E; Cooper S; Li Z H; Lu L; Sarris A; Wang M H; Chang M S; Donner D B; Leonard E J
Macrophage-stimulating protein, a ligand for the RON receptor protein tyrosine kinase, suppresses myeloid progenitor cell proliferation and synergizes with vascular endothelial cell growth factor and members of the chemokine family.
Annals of hematology 1996;73(1):1-9.
1996: Horie M; Sakamoto K M; Broxmeyer H E
Regulation of egr-1 gene expression by retinoic acid in a human growth factor-dependent cell line.
International journal of hematology 1996;63(4):303-9.
1996: Broxmeyer H E
Is interleukin 17, an inducible cytokine that stimulates production of other cytokines, merely a redundant player in a sea of other biomolecules?
The Journal of experimental medicine 1996;183(6):2411-5.
1996: Lisovsky M; Braun S E; Ge Y; Takahira H; Lu L; Savchenko V G; Lyman S D; Broxmeyer H E
Flt3-ligand production by human bone marrow stromal cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(6):1012-8.
1996: Aronica S M; Broxmeyer H E
Advances in understanding the postreceptor mechanisms of action of GM-CSF, G-CSF, and Steel factor.
Current opinion in hematology 1996;3(3):185-90.
1996: Ritchie A; Vadhan-Raj S; Broxmeyer H E
Thrombopoietin suppresses apoptosis and behaves as a survival factor for the human growth factor-dependent cell line, M07e.
Stem cells (Dayton, Ohio) 1996;14(3):330-6.
1996: Xiao M; Li Z H; McMahel J; Broxmeyer H E; Lu L
Inhibitory effects of interleukin 12 on retroviral gene transduction into CD34 cord blood myeloid progenitors mediated by induction of tumor necrosis factor-alpha.
Journal of hematotherapy 1996;5(2):171-7.
1996: Takahira H; Lyman S D; Broxmeyer H E
Flt3 ligand prolongs survival of CD34++ + human umbilical cord blood myeloid progenitors in serum-depleted culture medium.
Annals of hematology 1996;72(3):131-5.
1996: Lu L; Li Z H; Broxmeyer H E
Recovery and characterization of CD34+ cord blood cells after cryopreservation.
In vivo (Athens, Greece) 1996;10(2):229-32.
1996: Shen R N; Lu L; Kaiser H E; Broxmeyer H E
Curative effect of split low dosage total-body irradiation on murine AIDS induced by Friend virus: the results and the possible mechanism.
In vivo (Athens, Greece) 1996;10(2):191-9.
1996: Lu L; Shen R N; Broxmeyer H E
Stem cells from bone marrow, umbilical cord blood and peripheral blood for clinical application: current status and future application.
Critical reviews in oncology/hematology 1996;22(2):61-78.
1996: Lu L; Ge Y; Li Z H; Xiao M; Broxmeyer H E
Influence of retroviral-mediated gene transduction of both the recombinant human erythropoietin receptor and interleukin-9 receptor genes into single CD34++CD33-or low cord blood cells on cytokine-stimulated erythroid colony formation.
Experimental hematology 1996;24(2):347-51.
1996: Lu L; Ge Y; Li Z H; Keeble W; Kabat D; Bagby G C; Broxmeyer H E; Hoatlin M E
Retroviral transfer of the recombinant human erythropoietin receptor gene into single hematopoietic stem/progenitor cells from human cord blood increases the number of erythropoietin-dependent erythroid colonies.
Blood 1996;87(2):525-34.
1996: Cheng J; Baumhueter S; Cacalano G; Carver-Moore K; Thibodeaux H; Thomas R; Broxmeyer H E; Cooper S; Hague N; Moore M; Lasky L A
Hematopoietic defects in mice lacking the sialomucin CD34.
Blood 1996;87(2):479-90.
1995: Broxmeyer H E; Cooper S; Etienne-Julan M; Wang X S; Ponnazhagan S; Braun S; Lu L; Srivastava A
Cord blood transplantation and the potential for gene therapy. Gene transduction using a recombinant adeno-associated viral vector.
Annals of the New York Academy of Sciences 1995;770():105-15.
1995: Broxmeyer H E; Cooper S; Li Z H; Lu L; Song H Y; Kwon B S; Warren R E; Donner D B
Myeloid progenitor cell regulatory effects of vascular endothelial cell growth factor.
International journal of hematology 1995;62(4):203-15.
1995: Luo F; Zhou S Z; Cooper S; Munshi N C; Boswell H S; Broxmeyer H E; Srivastava A
Adeno-associated virus 2-mediated gene transfer and functional expression of the human granulocyte-macrophage colony-stimulating factor.
Experimental hematology 1995;23(12):1261-7.
1995: Broxmeyer H E; Cooper S; Hague N; Benninger L; Sarris A; Cornetta K; Vadhan-Raj S; Hendrie P; Mantel C
Human chemokines: enhancement of specific activity and effects in vitro on normal and leukemic progenitors and a factor-dependent cell line and in vivo in mice.
Annals of hematology 1995;71(5):235-46.
1995: Gotoh A; Miyazawa K; Ohyashiki K; Tauchi T; Boswell H S; Broxmeyer H E; Toyama K
Tyrosine phosphorylation and activation of focal adhesion kinase (p125FAK) by BCR-ABL oncoprotein.
Experimental hematology 1995;23(11):1153-9.
1995: Li Z H; Broxmeyer H E; Lu L
Cryopreserved cord blood myeloid progenitor cells can serve as targets for retroviral-mediated gene transduction and gene-transduced progenitors can be cryopreserved and recovered.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9 Suppl 1():S12-6.
1995: Lu L; Ge Y; Li Z H; Freie B; Clapp D W; Broxmeyer H E
CD34 stem/progenitor cells purified from cryopreserved normal cord blood can be transduced with high efficiency by a retroviral vector and expanded ex vivo with stable integration and expression of Fanconi anemia complementation C gene.
Cell transplantation 1995;4(5):493-503.
1995: Lu L; Xiao M; Li Z H; Jolliffe L K; Jones S; Broxmeyer H E; Weich N
Influence in vitro of IL-3/Epo fusion proteins compared with the combination of IL-3 plus Epo in enhancing the proliferation of single isolated erythroid and multipotential progenitor cells from human umbilical cord blood and adult bone marrow.
Experimental hematology 1995;23(10):1130-4.
1995: Youn B S; Jang I K; Broxmeyer H E; Cooper S; Jenkins N A; Gilbert D J; Copeland N G; Elick T A; Fraser M J; Kwon B S
A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(5):2661-7.
1995: Aronica S M; Mantel C; Gonin R; Marshall M S; Sarris A; Cooper S; Hague N; Zhang X F; Broxmeyer H E
Interferon-inducible protein 10 and macrophage inflammatory protein-1 alpha inhibit growth factor stimulation of Raf-1 kinase activity and protein synthesis in a human growth factor-dependent hematopoietic cell line.
The Journal of biological chemistry 1995;270(37):21998-2007.
1995: Broxmeyer H E; Lu L; Cooper S; Ruggieri L; Li Z H; Lyman S D
Flt3 ligand stimulates/costimulates the growth of myeloid stem/progenitor cells.
Experimental hematology 1995;23(10):1121-9.
1995: Broxmeyer H E
Questions to be answered regarding umbilical cord blood hematopoietic stem and progenitor cells and their use in-transplantation.
Transfusion 1995;35(8):694-702.
1995: Hiett A K; Britton K A; Hague N L; Brown H L; Stehman F B; Broxmeyer H E
Comparison of hematopoietic progenitor cells in human umbilical cord blood collected from neonatal infants who are small and appropriate for gestational age.
Transfusion 1995;35(7):587-91.
1995: Mantel C; Luo Z; Broxmeyer H E
Synergistic induction of phospholipid metabolism by granulocyte-macrophage colony stimulating factor and steel factor in human growth factor-dependent cell line, M07e.
Lipids 1995;30(7):641-7.
1995: Gaddy J; Risdon G; Broxmeyer H E
Cord blood natural killer cells are functionally and phenotypically immature but readily respond to interleukin-2 and interleukin-12.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995;15(6):527-36.
1995: Yip-Schneider M T; Horie M; Broxmeyer H E
Transcriptional induction of pim-1 protein kinase gene expression by interferon gamma and posttranscriptional effects on costimulation with steel factor.
Blood 1995;85(12):3494-502.
1995: Broxmeyer H E; Benninger L; Cooper S; Hague N; Benjamin R S; Vadhan-Raj S
Effects of in vivo treatment with PIXY321 (GM-CSF/IL-3 fusion protein) on proliferation kinetics of bone marrow and blood myeloid progenitor cells in patients with sarcoma.
Experimental hematology 1995;23(4):335-40.
1995: Tauchi T; Broxmeyer H E
BCR/ABL signal transduction.
International journal of hematology 1995;61(3):105-12.
1995: Risdon G; Gaddy J; Horie M; Broxmeyer H E
Alloantigen priming induces a state of unresponsiveness in human umbilical cord blood T cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):2413-7.
1995: Tauchi T; Feng G S; Shen R; Hoatlin M; Bagby G C; Kabat D; Lu L; Broxmeyer H E
Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways.
The Journal of biological chemistry 1995;270(10):5631-5.
1995: Mantel C; Aronica S; Luo Z; Marshall M S; Kim Y J; Cooper S; Hague N; Broxmeyer H E
Macrophage inflammatory protein-1 alpha enhances growth factor-stimulated phosphatidylcholine metabolism and increases cAMP levels in the human growth factor-dependent cell line M07e, events associated with growth suppression.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(5):2342-50.
1995: Broxmeyer H E
Cord blood as an alternative source for stem and progenitor cell transplantation.
Current opinion in pediatrics 1995;7(1):47-55.
1995: Miyazawa K; Williams D A; Gotoh A; Nishimaki J; Broxmeyer H E; Toyama K
Membrane-bound Steel factor induces more persistent tyrosine kinase activation and longer life span of c-kit gene-encoded protein than its soluble form.
Blood 1995;85(3):641-9.
1995: Horie M; Broxmeyer H E
The combination of Steel factor and GM-CSF blocks apoptosis induced by retinoic acid and upregulates AP-1 in a human growth factor-dependent cell line.
Experimental hematology 1995;23(2):168-73.
1994: Shen R N; Lu L; Kaiser H E; Broxmeyer H E
Bio-immunotherapy for cancer in experimental studies and clinical application: current status and future challenges.
In vivo (Athens, Greece) 1994;8(5):643-52.
1994: Tauchi T; Feng G S; Marshall M S; Shen R; Mantel C; Pawson T; Broxmeyer H E
The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells.
The Journal of biological chemistry 1994;269(40):25206-11.
1994: Shen R N; Lu L; Young P; Shidnia H; Hornback N B; Broxmeyer H E
Influence of elevated temperature on natural killer cell activity, lymphokine-activated killer cell activity and lectin-dependent cytotoxicity of human umbilical cord blood and adult blood cells.
International journal of radiation oncology, biology, physics 1994;29(4):821-6.
1994: Hendrie P C; Broxmeyer H E
Myeloid cell proliferation stimulated by Steel factor is pertussis toxin sensitive and enhanced by cholera toxin.
International journal of immunopharmacology 1994;16(7):547-60.
1994: Zhou S Z; Cooper S; Kang L Y; Ruggieri L; Heimfeld S; Srivastava A; Broxmeyer H E
Adeno-associated virus 2-mediated high efficiency gene transfer into immature and mature subsets of hematopoietic progenitor cells in human umbilical cord blood.
The Journal of experimental medicine 1994;179(6):1867-75.
1994: Broxmeyer H E
Advances in understanding of biological effects of interleukin-11, leukemia inhibitory factor, and macrophage inflammatory protein 1 alpha.
Current opinion in hematology 1994;1(3):197-202.
1994: Tauchi T; Feng G S; Shen R; Song H Y; Donner D; Pawson T; Broxmeyer H E
SH2-containing phosphotyrosine phosphatase Syp is a target of p210bcr-abl tyrosine kinase.
The Journal of biological chemistry 1994;269(21):15381-7.
1994: Risdon G; Gaddy J; Stehman F B; Broxmeyer H E
Proliferative and cytotoxic responses of human cord blood T lymphocytes following allogeneic stimulation.
Cellular immunology 1994;154(1):14-24.
1994: Cooper S; Mantel C; Broxmeyer H E
Myelosuppressive effects in vivo with very low dosages of monomeric recombinant murine macrophage inflammatory protein-1 alpha.
Experimental hematology 1994;22(2):186-93.
1994: Shen R N; Wu B; Lu L; Kaiser H E; Broxmeyer H E
Recombinant human interleukin-1 alpha: a potent bio-immunomodifier in vivo in immunosuppressed mice induced by cyclophosphamide, retroviral infection and surgical stress.
In vivo (Athens, Greece) 1994;8(1):59-63.
1994: Broxmeyer H E; Benninger L; Patel S R; Benjamin R S; Vadhan-Raj S
Kinetic response of human marrow myeloid progenitor cells to in vivo treatment of patients with granulocyte colony-stimulating factor is different from the response to treatment with granulocyte-macrophage colony-stimulating factor.
Experimental hematology 1994;22(1):100-2.
1994: Miyazawa K; Toyama K; Gotoh A; Hendrie P C; Mantel C; Broxmeyer H E
Ligand-dependent polyubiquitination of c-kit gene product: a possible mechanism of receptor down modulation in M07e cells.
Blood 1994;83(1):137-45.
1994: Tauchi T; Boswell H S; Leibowitz D; Broxmeyer H E
Coupling between p210bcr-abl and Shc and Grb2 adaptor proteins in hematopoietic cells permits growth factor receptor-independent link to ras activation pathway.
The Journal of experimental medicine 1994;179(1):167-75.
1994: Mantel C; Miyazawa K; Broxmeyer H E
Physical characteristics and polymerization during iron saturation of lactoferrin, a myelopoietic regulatory molecule with suppressor activity.
Advances in experimental medicine and biology 1994;357():121-32.
1994: Risdon G; Gaddy J; Broxmeyer H E
Allogeneic responses of human umbilical cord blood.
Blood cells 1994;20(2-3):566-70; discussion 571-2.
1994: Lu L; Xiao M; Clapp D W; Li Z H; Broxmeyer H E
Stable integration of retrovirally transduced genes into human umbilical cord blood high-proliferative potential colony-forming cells (HPP-CFC) as assessed after multiple HPP-CFC colony replatings in vitro.
Blood cells 1994;20(2-3):525-30.
1994: Broxmeyer H E; Benninger L; Yip-Schneider M; Braun S E
Commentary: a rapid proliferation assay for unknown co-stimulating factors in cord blood plasma possibly involved in enhancement of in vitro expansion and replating capacity of human hematopoietic stem/progenitor cells.
Blood cells 1994;20(2-3):492-7.
1994: Orazi A; Braun S E; Broxmeyer H E
Commentary: Immunohistochemistry represents a useful tool to study human cell engraftment in SCID mice transplantation models.
Blood cells 1994;20(2-3):323-30.
1994: Shi Y J; Shen R N; Lu L; Broxmeyer H E
Comparative analysis of retroviral-mediated gene transduction into CD34+ cord blood hematopoietic progenitors in the presence and absence of growth factors.
Blood cells 1994;20(2-3):517-24.
1994: Xiao M; Broxmeyer H E; Horie M; Grigsby S; Lu L
Extensive proliferative capacity of single isolated CD34 human cord blood cells in suspension culture.
Blood cells 1994;20(2-3):455-66; discussion 466-7.
1994: Ruggieri L; Heimfeld S; Broxmeyer H E
Cytokine-dependent ex vivo expansion of early subsets of CD34+ cord blood myeloid progenitors is enhanced by cord blood plasma, but expansion of the more mature subsets of progenitors is favored.
Blood cells 1994;20(2-3):436-54.
1993: Yip-Schneider M T; Horie M; Broxmeyer H E
Characterization of interleukin-7-induced changes in tyrosine phosphorylation and c-myc gene expression in normal human T cells.
Experimental hematology 1993;21(13):1648-56.
1993: Mantel C; Luo Z; Hendrie P; Broxmeyer H E
Steel factor and granulocyte-macrophage colony stimulating factor act together to enhance choline-lipid turnover during synergistically stimulated proliferation of the human factor dependent cell line, M07E.
Biochemical and biophysical research communications 1993;197(2):978-84.
1993: Lu L; Xiao M; Clapp D W; Li Z H; Broxmeyer H E
High efficiency retroviral mediated gene transduction into single isolated immature and replatable CD34(3+) hematopoietic stem/progenitor cells from human umbilical cord blood.
The Journal of experimental medicine 1993;178(6):2089-96.
1993: Zhou Z; Kim Y J; Pollok K; Hurtado J; Lee J K; Broxmeyer H E; Kwon B S
Macrophage inflammatory protein-1 alpha rapidly modulates its receptors and inhibits the anti-CD3 mAb-mediated proliferation of T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(8):4333-41.
1993: Lu L; Xiao M; Wu B; Wang W X; Yan W R; Broxmeyer H E; Shen R N
In vivo effects of purified recombinant human macrophage colony-stimulating factor in combination with local hyperthermia on tumor progression in B16a melanoma bearing mice.
International journal of hematology 1993;58(3):139-52.
1993: Lu L; Xiao M; Grigsby S; Wang W X; Wu B; Shen R N; Broxmeyer H E
Comparative effects of suppressive cytokines on isolated single CD34(3+) stem/progenitor cells from human bone marrow and umbilical cord blood plated with and without serum.
Experimental hematology 1993;21(11):1442-6.
1993: Wu B; Shen R N; Wang W X; Broxmeyer H E; Lu L
Antitumor effect of interleukin 7 in combination with local hyperthermia in mice bearing B16a melanoma cells.
Stem cells (Dayton, Ohio) 1993;11(5):412-21.
1993: Zhou S Z; Broxmeyer H E; Cooper S; Harrington M A; Srivastava A
Adeno-associated virus 2-mediated gene transfer in murine hematopoietic progenitor cells.
Experimental hematology 1993;21(7):928-33.
1993: Hangoc G; Daub R; Maze R G; Falkenburg J H; Broxmeyer H E; Harrington M A
Regulation of myelopoiesis by murine fibroblastic and adipogenic cell lines.
Experimental hematology 1993;21(4):502-7.
1993: Broxmeyer H E; Sherry B; Cooper S; Lu L; Maze R; Beckmann M P; Cerami A; Ralph P
Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells. Interacting effects involving suppression, synergistic suppression, and blocking of suppression.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(8 Pt 1):3448-58.
1993: Maze R; Horie M; Hendrie P; Vadhan-Raj S; Tricot G; Gordon M; Nemunaitis J; Ashman L K; Broxmeyer H E
Differential responses of myeloid progenitor cells from patients with myeloid leukemia and myelodysplasia to the costimulating effects of steel factor in vitro.
Experimental hematology 1993;21(4):545-51.
1993: Mantel C; Kim Y J; Cooper S; Kwon B; Broxmeyer H E
Polymerization of murine macrophage inflammatory protein 1 alpha inactivates its myelosuppressive effects in vitro: the active form is a monomer.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2232-6.
1993: Hangoc G; Yin T; Cooper S; Schendel P; Yang Y C; Broxmeyer H E
In vivo effects of recombinant interleukin-11 on myelopoiesis in mice.
Blood 1993;81(4):965-72.
1993: Carow C E; Hangoc G; Broxmeyer H E
Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: an effect enhanced by cord blood plasma.
Blood 1993;81(4):942-9.
1993: Horie M; Broxmeyer H E
Involvement of immediate-early gene expression in the synergistic effects of steel factor in combination with granulocyte-macrophage colony-stimulating factor or interleukin-3 on proliferation of a human factor-dependent cell line.
The Journal of biological chemistry 1993;268(2):968-73.
1993: Carow C E; Harrington M A; Broxmeyer H E
Detection of human myeloid progenitor cells in a murine background.
Experimental hematology 1993;21(1):66-9.
1993: Lu L; Xiao M; Shen R N; Grigsby S; Broxmeyer H E
Enrichment, characterization, and responsiveness of single primitive CD34 human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential.
Blood 1993;81(1):41-8.
1992: Hangoc G; Carow C E; Schwall R; Mason A J; Broxmeyer H E
Effects in vivo of recombinant human inhibin on myelopoiesis in mice.
Experimental hematology 1992;20(10):1243-6.
1992: Broxmeyer H E
Interactions of colony stimulating factors, other modulating cytokines and hematopoietic progenitor cells. Laboratory and clinical studies.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1992;6 Suppl 4():38-40.
1992: Miyazawa K; Hendrie P C; Kim Y J; Mantel C; Yang Y C; Kwon B S; Broxmeyer H E
Recombinant human interleukin-9 induces protein tyrosine phosphorylation and synergizes with steel factor to stimulate proliferation of the human factor-dependent cell line, M07e.
Blood 1992;80(7):1685-92.
1992: Lu L; Zhou Z; Wu B; Xiao M; Shen R N; Williams D E; Kim Y J; Kwon B S; Ruscetti S; Broxmeyer H E
Influence of recombinant human interleukin (IL)-7 on disease progression in mice infected with Friend virus complex.
International journal of cancer. Journal international du cancer 1992;52(2):261-5.
1992: Maze R; Sherry B; Kwon B S; Cerami A; Broxmeyer H E
Myelosuppressive effects in vivo of purified recombinant murine macrophage inflammatory protein-1 alpha.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(3):1004-9.
1992: Broxmeyer H E; Hangoc G; Cooper S; Ribeiro R C; Graves V; Yoder M; Wagner J; Vadhan-Raj S; Benninger L; Rubinstein P
Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):4109-13.
1992: Xiao M; Leemhuis T; Broxmeyer H E; Lu L
Influence of combinations of cytokines on proliferation of isolated single cell-sorted human bone marrow hematopoietic progenitor cells in the absence and presence of serum.
Experimental hematology 1992;20(2):276-9.
1992: Broxmeyer H E
Suppressor cytokines and regulation of myelopoiesis. Biology and possible clinical uses.
The American journal of pediatric hematology/oncology 1992;14(1):22-30.
1992: Broxmeyer H E; Hangoc G; Cooper S
Clinical and biological aspects of human umbilical cord blood as a source of transplantable hematopoietic stem and progenitor cells.
Bone marrow transplantation 1992;9 Suppl 1():7-10.
1992: Broxmeyer H E; Cooper S; Yoder M; Hangoc G
Human umbilical cord blood as a source of transplantable hematopoietic stem and progenitor cells.
Current topics in microbiology and immunology 1992;177():195-204.
1991: Broxmeyer H E; Hangoc G; Zucali J R; Mason A; Schwall R; Carow C; Cooper S
Effects in vivo of purified recombinant human activin and erythropoietin in mice.
International journal of hematology 1991;54(6):447-54.
1991: Broxmeyer H E; Maze R; Miyazawa K; Carow C; Hendrie P C; Cooper S; Hangoc G; Vadhan-Raj S; Lu L
The kit receptor and its ligand, steel factor, as regulators of hemopoiesis.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1991;3(12):480-7.
1991: Miyazawa K; Hendrie P C; Mantel C; Wood K; Ashman L K; Broxmeyer H E
Comparative analysis of signaling pathways between mast cell growth factor (c-kit ligand) and granulocyte-macrophage colony-stimulating factor in a human factor-dependent myeloid cell line involves phosphorylation of Raf-1, GTPase-activating protein and mitogen-activated protein kinase.
Experimental hematology 1991;19(11):1110-23.
1991: Carow C E; Hangoc G; Cooper S H; Williams D E; Broxmeyer H E
Mast cell growth factor (c-kit ligand) supports the growth of human multipotential progenitor cells with a high replating potential.
Blood 1991;78(9):2216-21.
1991: Hendrie P C; Miyazawa K; Yang Y C; Langefeld C D; Broxmeyer H E
Mast cell growth factor (c-kit ligand) enhances cytokine stimulation of proliferation of the human factor-dependent cell line, M07e.
Experimental hematology 1991;19(10):1031-7.
1991: Oh K O; Zhou Z; Kim K K; Samanta H; Fraser M; Kim Y J; Broxmeyer H E; Kwon B S
Identification of cell surface receptors for murine macrophage inflammatory protein-1 alpha.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(9):2978-83.
1991: Broxmeyer H E; Sherry B; Cooper S; Ruscetti F W; Williams D E; Arosio P; Kwon B S; Cerami A
Macrophage inflammatory protein (MIP)-1 beta abrogates the capacity of MIP-1 alpha to suppress myeloid progenitor cell growth.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(8):2586-94.
1991: Lu L; Shen R N; Broxmeyer H E
In vivo effects of recombinant human interleukin 6, alone or in combination with local irradiation, on tumor growth in Lewis lung carcinoma-bearing mice.
International journal of cell cloning 1991;9(5):511-20.
1991: Lu L; Shen R N; Zhou S Z; Wu B; Kim Y J; Lin Z H; Ruscetti S; Ralph P; Broxmeyer H E
Efficacy of recombinant human macrophage colony-stimulating factor in combination with whole-body hyperthermia in the treatment of mice infected with the polycythemia-inducing strain of the Friend virus complex.
Experimental hematology 1991;19(8):804-9.
1991: Hangoc G; Falkenburg J H; Broxmeyer H E
Influence of T-lymphocytes and lactoferrin on the survival-promoting effects of IL-1 and IL-6 on human bone marrow granulocyte-macrophage and erythroid progenitor cells.
Experimental hematology 1991;19(7):697-703.
1991: Falkenburg J H; Harrington M A; de Paus R A; Walsh W K; Daub R; Landegent J E; Broxmeyer H E
Differential transcriptional and posttranscriptional regulation of gene expression of the colony-stimulating factors by interleukin-1 and fetal bovine serum in murine fibroblasts.
Blood 1991;78(3):658-65.
1991: Broxmeyer H E; Lu L; Hangoc G; Cooper S; Hendrie P C; Ledbetter J A; Xiao M; Williams D E; Shen F W
CD45 cell surface antigens are linked to stimulation of early human myeloid progenitor cells by interleukin 3 (IL-3), granulocyte/macrophage colony-stimulating factor (GM-CSF), a GM-CSF/IL-3 fusion protein, and mast cell growth factor (a c-kit ligand).
The Journal of experimental medicine 1991;174(2):447-58.
1991: Harrington M A; Edenberg H J; Saxman S; Pedigo L M; Daub R; Broxmeyer H E
Cloning and characterization of the murine promoter for the colony-stimulating factor-1-encoding gene.
Gene 1991;102(2):165-70.
1991: Broxmeyer H E; Cooper S; Lu L; Hangoc G; Anderson D; Cosman D; Lyman S D; Williams D E
Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells.
Blood 1991;77(10):2142-9.
1991: Shen R N; Lu L; Feng G S; Miller J; Taylor M W; Broxmeyer H E
Cure with low-dose total-body irradiation of the hematological disorder induced in mice with the Friend virus: possible mechanism involving interferon-gamma and interleukin-2.
Lymphokine and cytokine research 1991;10(1-2):105-9.
1991: Lu L; Shen R N; Zhou S Z; Srivastava C; Harrington M; Miyazawa K; Wu B; Lin Z H; Ruscetti S; Broxmeyer H E
Synergistic effect of human lactoferrin and recombinant murine interferon-gamma on disease progression in mice infected with the polycythemia-inducing strain of the Friend virus complex.
International journal of hematology 1991;54(2):117-24.
1991: Shen R N; Lu L; Harrington M A; Srivastava C; Kim Y J; Zhou S Z; Wu B; Ruscetti S; Broxmeyer H E
Effect of split low dose total body irradiation on SFFV mRNA, genomic DNA and protein expression in mice infected with the Friend virus complex.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1991;5(3):225-9.
1991: Shen R N; Hornback N B; Shidnia H; Wu B; Lu L; Broxmeyer H E
Whole body hyperthermia: a potent radioprotector in vivo.
International journal of radiation oncology, biology, physics 1991;20(3):525-30.
1991: Broxmeyer H E; Cooper S; Levi S; Arosio P
Mutated recombinant human heavy-chain ferritins and myelosuppression in vitro and in vivo: a link between ferritin ferroxidase activity and biological function.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(3):770-4.
1991: Broxmeyer H E; Hangoc G; Cooper S; Anderson D; Cosman D; Lyman S D; Williams D E
Influence of murine mast cell growth factor (c-kit ligand) on colony formation by mouse marrow hematopoietic progenitor cells.
Experimental hematology 1991;19(2):143-6.
1991: Srivastava C H; Rado T A; Bauerle D; Broxmeyer H E
Regulation of human bone marrow lactoferrin and myeloperoxidase gene expression by tumor necrosis factor-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(3):1014-9.
1991: Lu L; Shen R N; Lin Z H; Aukerman S L; Ralph P; Broxmeyer H E
Anti-tumor effects of recombinant human macrophage colony-stimulating factor, alone or in combination with local irradiation, in mice inoculated with Lewis lung carcinoma cells.
International journal of cancer. Journal international du cancer 1991;47(1):143-7.
1991: Miyazawa K; Mantel C; Lu L; Morrison D C; Broxmeyer H E
Lactoferrin-lipopolysaccharide interactions. Effect on lactoferrin binding to monocyte/macrophage-differentiated HL-60 cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(2):723-9.
1991: Gentile P; Broxmeyer H E
Interleukin-6 ablates the accessory cell-mediated suppressive effects of lactoferrin on human hematopoietic progenitor cell proliferation in vitro.
Annals of the New York Academy of Sciences 1991;628():74-83.
1991: Broxmeyer H E; Bicknell D C; Cooper S; Sledge G; Williams D E; McGuire W A; Coates T D
Qualitative functional deficiency of affinity-purified lactoferrin from neutrophils of patients with chronic myelogenous leukemia, and lactoferrin/H-ferritin-cell interactions in a patient with lactoferrin-deficiency with normal numbers of circulating leukocytes.
Pathobiology : journal of immunopathology, molecular and cellular biology 1991;59(1):26-35.
1991: Broxmeyer H E; Mantel C; Gentile P; Srivastava C; Miyazawa K; Zucali J R; Rado T A; Levi S; Arosio P
Actions of H-subunit ferritin and lactoferrin as suppressor molecules of myelopoiesis in vitro and in vivo.
Current studies in hematology and blood transfusion 1991;(58):178-81.
1991: Broxmeyer H E
Self-renewal and migration of stem cells during embryonic and fetal hematopoiesis: important, but poorly understood events.
Blood cells 1991;17(2):282-6.
1991: Broxmeyer H E; Kurtzberg J; Gluckman E; Auerbach A D; Douglas G; Cooper S; Falkenburg J H; Bard J; Boyse E A
Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation.
Blood cells 1991;17(2):313-29.
1990: Lu L; Lin Z H; Shen R N; Warren D J; Leemhuis T; Broxmeyer H E
Influence of interleukins 3,5, and 6 on the growth of eosinophil progenitors in highly enriched human bone marrow in the absence of serum.
Experimental hematology 1990;18(11):1180-6.
1990: Broxmeyer H E; Sherry B; Lu L; Cooper S; Oh K O; Tekamp-Olson P; Kwon B S; Cerami A
Enhancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitro by bone marrow myeloid progenitor cells.
Blood 1990;76(6):1110-6.
1990: Harrington M A; Falkenburg J H; Daub R; Broxmeyer H E
Effect of myogenic and adipogenic differentiation on expression of colony-stimulating factor genes.
Molecular and cellular biology 1990;10(9):4948-52.
1990: Shen R N; Lu L; Wu B; Shidnia H; Hornback N B; Broxmeyer H E
Effects of interleukin 2 treatment combined with local hyperthermia in mice inoculated with Lewis lung carcinoma cells.
Cancer research 1990;50(16):5027-30.
1990: Broxmeyer H E; Cooper S; Lu L; Miller M E; Langefeld C D; Ralph P
Enhanced stimulation of human bone marrow macrophage colony formation in vitro by recombinant human macrophage colony-stimulating factor in agarose medium and at low oxygen tension.
Blood 1990;76(2):323-9.
1990: Falkenburg J H; Harrington M A; Walsh W K; Daub R; Broxmeyer H E
Gene-expression and release of macrophage-colony stimulating factor in quiescent and proliferating fibroblasts. Effects of serum, fibroblast growth-promoting factors, and IL-1.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(12):4657-62.
1990: Broxmeyer H E; Gluckman E; Auerbach A; Douglas G W; Friedman H; Cooper S; Hangoc G; Kurtzberg J; Bard J; Boyse E A
Human umbilical cord blood: a clinically useful source of transplantable hematopoietic stem/progenitor cells.
International journal of cell cloning 1990;8 Suppl 1():76-89; discussion 89-91.
1989: Broxmeyer H E; Sherry B; Lu L; Cooper S; Carow C; Wolpe S D; Cerami A
Myelopoietic enhancing effects of murine macrophage inflammatory proteins 1 and 2 on colony formation in vitro by murine and human bone marrow granulocyte/macrophage progenitor cells.
The Journal of experimental medicine 1989;170(5):1583-94.
1989: Lu L; Foa P; Chillemi F; Shen R N; Lin Z H; Carow C; Broxmeyer H E
Suppressive biological activity of a synthetic pentapeptide on highly enriched human and murine marrow hematopoietic progenitors: synergism with recombinant human tumor necrosis factor-alpha and interferon-gamma.
Experimental hematology 1989;17(9):935-41.
1989: Geissler K; Harrington M; Srivastava C; Leemhuis T; Tricot G; Broxmeyer H E
Effects of recombinant human colony stimulating factors (CSF) (granulocyte-macrophage CSF, granulocyte CSF, and CSF-1) on human monocyte/macrophage differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(1):140-6.
1989: Hangoc G; Williams D E; Falkenburg J H; Broxmeyer H E
Influence of IL-1 alpha and -1 beta on the survival of human bone marrow cells responding to hematopoietic colony-stimulating factors.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(12):4329-34.
1989: Broxmeyer H E; Cooper S; Vadhan-Raj S
Cell cycle status of erythroid (BFU-E) progenitor cells from the bone marrows of patients on a clinical trial with purified recombinant human granulocyte-macrophage colony-stimulating factor.
Experimental hematology 1989;17(5):455-9.
1989: Geissler K; Tricot G; Leemhuis T; Walker E; Broxmeyer H E
Differentiation-inducing effect of recombinant human tumor necrosis factor alpha and gamma-interferon in vitro on blast cells from patients with acute myeloid leukemia and myeloid blast crisis of chronic myeloid leukemia.
Cancer research 1989;49(11):3057-62.
1989: Broxmeyer H E; Douglas G W; Hangoc G; Cooper S; Bard J; English D; Arny M; Thomas L; Boyse E A
Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3828-32.
1989: Broxmeyer H E; Williams D E; Geissler K; Hangoc G; Cooper S; Bicknell D C; Levi S; Arosio P
Suppressive effects in vivo of purified recombinant human H-subunit (acidic) ferritin on murine myelopoiesis.
Blood 1989;73(1):74-9.
1989: Shen R N; Hornback N B; Lu L; Chen L T; Brahmi Z; Broxmeyer H E
Low dose total body irradiation: a potent anti-retroviral agent in vivo.
International journal of radiation oncology, biology, physics 1989;16(1):165-70.
1989: Broxmeyer H E; Cooper S; Gabig T
The effects of oxidizing species derived from molecular oxygen on the proliferation in vitro of human granulocyte-macrophage progenitor cells.
Annals of the New York Academy of Sciences 1989;554():177-84.
1989: Broxmeyer H E; Vadhan-Raj S
Preclinical and clinical studies with the hematopoietic colony-stimulating factors and related interleukins.
Immunologic research 1989;8(3):185-201.
1989: Broxmeyer H E; Geissler K; Cooper S; Williams D E
Influence of purified recombinant human macrophage colony stimulating factor in mice.
Biotechnology therapeutics 1989;1(1):43-54.
1989: Hangoc G; Broxmeyer H E
Effects of purified recombinant human interleukin-3 on the growth of human hematopoietic progenitor cells in "long-term" bone marrow culture.
Biotechnology therapeutics 1989;1(1):17-29.
1988: Broxmeyer H E; Lu L; Cooper S; Schwall R H; Mason A J; Nikolics K
Selective and indirect modulation of human multipotential and erythroid hematopoietic progenitor cell proliferation by recombinant human activin and inhibin.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):9052-6.
1988: Broxmeyer H E; Lu L; Cooper S; Tushinski R; Mochizuki D; Rubin B Y; Gillis S; Williams D E
Synergistic effects of purified recombinant human and murine B cell growth factor-1/IL-4 on colony formation in vitro by hematopoietic progenitor cells. Multiple actions.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(11):3852-62.
1988: Williams D E; Broxmeyer H E
Interleukin-1 alpha enhances the in vitro survival of purified murine granulocyte-macrophage progenitor cells in the absence of colony-stimulating factors.
Blood 1988;72(5):1608-15.
1988: English D; Broxmeyer H E; Gabig T G; Akard L P; Williams D E; Hoffman R
Temporal adaptation of neutrophil oxidative responsiveness to n-formyl-methionyl-leucyl-phenylalanine. Acceleration by granulocyte-macrophage colony stimulating factor.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(7):2400-6.
1988: Broxmeyer H E; Williams D E; Cooper S; Hangoc G; Ralph P
Recombinant human granulocyte-colony stimulating factor and recombinant human macrophage-colony stimulating factor synergize in vivo to enhance proliferation of granulocyte-macrophage, erythroid, and multipotential progenitor cells in mice.
Journal of cellular biochemistry 1988;38(2):127-36.
1988: Broxmeyer H E; Williams D E; Cooper S; Ralph P; Gillis S; Bicknell D C; Hangoc G; Drummond R; Lu L
Synergistic interaction of hematopoietic colony stimulating and growth factors in the regulation of myelopoiesis.
Behring Institute Mitteilungen 1988;(83):80-4.
1988: Broxmeyer H E; Cooper S; Williams D E; Hangoc G; Gutterman J U; Vadhan-Raj S
Growth characteristics of marrow hematopoietic progenitor/precursor cells from patients on a phase I clinical trial with purified recombinant human granulocyte-macrophage colony-stimulating factor.
Experimental hematology 1988;16(7):594-602.
1988: Shen R N; Hornback N B; Shidnia H; Lu L; Broxmeyer H E; Brahmi Z
Effect of whole-body hyperthermia and cyclophosphamide on natural killer cell activity in murine erythroleukemia.
Cancer research 1988;48(16):4561-3.
1988: Lu L; Walker D; Graham C D; Waheed A; Shadduck R K; Broxmeyer H E
Enhancement of release from MHC class II antigen-positive monocytes of hematopoietic colony stimulating factors CSF-1 and G-CSF by recombinant human tumor necrosis factor-alpha: synergism with recombinant human interferon-gamma.
Blood 1988;72(1):34-41.
1988: Lu L; Srour E F; Warren D J; Walker D; Graham C D; Walker E B; Jansen J; Broxmeyer H E
Enhancement of release of granulocyte- and granulocyte-macrophage colony-stimulating factors from phytohemagglutinin-stimulated sorted subsets of human T lymphocytes by recombinant human tumor necrosis factor-alpha. Synergism with recombinant human IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(1):201-7.
1988: Shen R N; Hornback N B; Lu L; Young P; Brahmi Z; Broxmeyer H E
Curative effect of split low dosage total-body irradiation on mice infected with the polycythemia-inducing strain of the Friend virus complex.
Cancer research 1988;48(9):2399-403.
1988: Bicknell D C; Williams D E; Broxmeyer H E
Correlation between CSF-1 responsiveness and expression of (CSF-1 receptor) c-fms in purified murine granulocyte-macrophage progenitor cells (CFU-GM).
Experimental hematology 1988;16(3):240-3.
1988: Williams D E; Cooper S; Broxmeyer H E
Effects of hematopoietic suppressor molecules on the in vitro proliferation of purified murine granulocyte-macrophage progenitor cells.
Cancer research 1988;48(6):1548-50.
1988: Williams D E; Bicknell D C; Park L S; Straneva J E; Cooper S; Broxmeyer H E
Purified murine granulocyte/macrophage progenitor cells express a high-affinity receptor for recombinant murine granulocyte/macrophage colony-stimulating factor.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(2):487-91.
1988: Bicknell D C; Williams D E; Broxmeyer H E
Correlation between CSF-1 responsiveness and expression of (CSF-1 receptor) c-fms in purified murine granulocyte-macrophage progenitor cells (CFU-GM).
Experimental hematology 1988;16(1):88-91.
1988: Broxmeyer H E; Vadhan-Raj S; Hangoc G; Lu L; Gutterman J U; Williams D E
Preclinical and clinical effects of the hematopoietic colony stimulating factors.
Advances in experimental medicine and biology 1988;241():233-41.
1988: Broxmeyer H E; Williams D E
The production of myeloid blood cells and their regulation during health and disease.
Critical reviews in oncology/hematology 1988;8(3):173-226.
1987: Hangoc G; Lu L; Oliff A; Gillis S; Hu W; Bicknell D C; Williams D; Broxmeyer H E
Modulation of Friend virus infectivity in vivo by administration of purified preparations of human lactoferrin and recombinant murine interleukin-3 to mice.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1987;1(11):762-4.
1987: Williams D E; Straneva J E; Cooper S; Shadduck R K; Waheed A; Gillis S; Urdal D; Broxmeyer H E
Interactions between purified murine colony-stimulating factors (natural CSF-1, recombinant GM-CSF, and recombinant IL-3) on the in vitro proliferation of purified murine granulocyte-macrophage progenitor cells.
Experimental hematology 1987;15(10):1007-12.
1987: Broxmeyer H E; Williams D E; Hangoc G; Cooper S; Gillis S; Shadduck R K; Bicknell D C
Synergistic myelopoietic actions in vivo after administration to mice of combinations of purified natural murine colony-stimulating factor 1, recombinant murine interleukin 3, and recombinant murine granulocyte/macrophage colony-stimulating factor.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(11):3871-5.
1987: Broxmeyer H E; Williams D E; Hangoc G; Cooper S; Gentile P; Shen R N; Ralph P; Gillis S; Bicknell D C
The opposing actions in vivo on murine myelopoiesis of purified preparations of lactoferrin and the colony stimulating factors.
Blood cells 1987;13(1-2):31-48.
1987: Williams D E; Lu L; Broxmeyer H E
Characterization of hematopoietic stem and progenitor cells.
Immunologic research 1987;6(4):294-304.
1987: Broxmeyer H E; Williams D E
Actions of hematopoietic colony-stimulating factors in vivo and in vitro.
Pathology and immunopathology research 1987;6(3):207-20.

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