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Ajay Singh

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Chemicals & Drugs

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Tumor Cell Line

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Publications

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Sangeeta Bafna; Ajay Singh; Nicolas Moniaux; James D Eudy; Jane L Meza; Surinder Batra
MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells.
Ajay Singh; Shantibhusan Senapati; Moorthy P Ponnusamy; Maneesh Jain; Subodh M Lele; John S Davis; Steven Remmenga; Surinder Batra
Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer.
Moorthy P Ponnusamy; Ajay Singh; Maneesh Jain; S Chakraborty; Nicolas Moniaux; Surinder Batra
MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells.

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All Publications

2008: Sangeeta Bafna; Ajay Singh; Nicolas Moniaux; James D Eudy; Jane L Meza; Surinder Batra
MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells.
Cancer research 2008;68(22):9231-8.
2008: Ajay Singh; Shantibhusan Senapati; Moorthy P Ponnusamy; Maneesh Jain; Subodh M Lele; John S Davis; Steven Remmenga; Surinder Batra
Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer.
The lancet oncology 2008;9(11):1076-85.
2008: Moorthy P Ponnusamy; Ajay Singh; Maneesh Jain; S Chakraborty; Nicolas Moniaux; Surinder Batra
MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells.
British journal of cancer 2008;99(3):520-6.
2008: Pallavi Chaturvedi; Ajay Singh; Subhankar Chakraborty; Subhash C Chauhan; Sangeeta Bafna; Jane L Meza; Pankaj K Singh; Michael A Hollingsworth; Parmender P Mehta; Surinder Batra
MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells.
Cancer research 2008;68(7):2065-70.
2008: Pallavi Chaturvedi; Ajay Singh; Surinder Batra
Structure, evolution, and biology of the MUC4 mucin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(4):966-81.
2008: Ajay Singh; Sangeeta Bafna; Kunal Chaudhary; Ganesh Venkatraman; Lynette Smith; James D Eudy; Sonny L Johansson; Ming-Fong Lin; Surinder Batra
Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells.
Cancer letters 2008;259(1):28-38.
2007: Mahefatiana Andrianifahanana; Ajay Singh; Christophe NEMOS; Moorthy P Ponnusamy; Nicolas Moniaux; Parmender P Mehta; Grish C Varshney; Surinder Batra
IFN-gamma-induced expression of MUC4 in pancreatic cancer cells is mediated by STAT-1 upregulation: a novel mechanism for IFN-gamma response.
Oncogene 2007;26(51):7251-61.
2007: Moorthy P Ponnusamy; Ganesh Venkatraman; Ajay Singh; Subhash C Chauhan; Sonny L Johansson; Maneesh Jain; Lynnette Smith; John S Davis; Steven W Remmenga; Surinder Batra
Expression of TAG-72 in ovarian cancer and its correlation with tumor stage and patient prognosis.
Cancer letters 2007;251(2):247-57.
2007: Pallavi Chaturvedi; Ajay Singh; Nicolas Moniaux; Shantibhushan Senapati; Subhankar Chakraborty; Jane L Meza; Surinder Batra
MUC4 mucin potentiates pancreatic tumor cell proliferation, survival, and invasive properties and interferes with its interaction to extracellular matrix proteins.
Molecular cancer research : MCR 2007;5(4):309-20.
2007: Siu-Ju Chen; Dev Karan; Sonny L Johansson; Fen-Fen Lin; Jeffrey Zeckser; Ajay Singh; Surinder Batra; Ming-Fong Lin
Prostate-derived factor as a paracrine and autocrine factor for the proliferation of androgen receptor-positive human prostate cancer cells.
The Prostate 2007;67(5):557-71.
2007: Ajay Singh; Pallavi Chaturvedi; Surinder Batra
Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy.
Cancer research 2007;67(2):433-6.
2007: Ajay Singh; Subhash C Chauhan; Mahefatiana Andrianifahanana; Nicolas Moniaux; Jane L Meza; Marie-Christine Copin; Isabelle Van Seuningen; Michael A Hollingsworth; Jean-Pierre Aubert; Surinder Batra
MUC4 expression is regulated by cystic fibrosis transmembrane conductance regulator in pancreatic adenocarcinoma cells via transcriptional and post-translational mechanisms.
Oncogene 2007;26(1):30-41.
2006: Uwe A Wittel; Ajay Singh; Brandon J Henley; Mahefatiana Andrianifahanana; Mohammed P Akhter; Diane M Cullen; Surinder Batra
Cigarette smoke-induced differential expression of the genes involved in exocrine function of the rat pancreas.
Pancreas 2006;33(4):364-70.
2006: Subhash C Chauhan; Ajay Singh; Fernanda Ruiz; Sonny L Johansson; Maneesh Jain; Lynette M Smith; Nicolas Moniaux; Surinder Batra
Aberrant expression of MUC4 in ovarian carcinoma: diagnostic significance alone and in combination with MUC1 and MUC16 (CA125).
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(10):1386-94.
2006: Nicolas Moniaux; Wade M Junker; Ajay Singh; Andria M Jones; Surinder Batra
Characterization of human mucin MUC17. Complete coding sequence and organization.
The Journal of biological chemistry 2006;281(33):23676-85.
2006: Ajay Singh; Subhash C Chauhan; Sangeeta Bafna; Sonny L Johansson; Lynette M Smith; Nicolas Moniaux; Ming-Fong Lin; Surinder Batra
Aberrant expression of transmembrane mucins, MUC1 and MUC4, in human prostate carcinomas.
The Prostate 2006;66(4):421-9.
2005: Mahefatiana Andrianifahanana; Anshu Aggarwal; Ajay Singh; Nicolas Moniaux; Isabelle Van Seuningen; Jean-Pierre Aubert; Jane L Meza; Surinder Batra
Synergistic induction of the MUC4 mucin gene by interferon-gamma and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways.
Oncogene 2005;24(40):6143-54.
2005: Maneesh Jain; Subhash C Chauhan; Ajay Singh; Ganesh Venkatraman; David Colcher; Surinder Batra
Penetratin improves tumor retention of single-chain antibodies: a novel step toward optimization of radioimmunotherapy of solid tumors.
Cancer research 2005;65(17):7840-6.
2004: Ajay Singh; Nicolas Moniaux; Subhash C Chauhan; Jane L Meza; Surinder Batra
Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis.
Cancer research 2004;64(2):622-30.
2003: Dev Karan; Siu-Ju Chen; Sonny L Johansson; Ajay Singh; Vishwas M Paralkar; Ming-Fong Lin; Surinder Batra
Dysregulated expression of MIC-1/PDF in human prostate tumor cells.
Biochemical and biophysical research communications 2003;305(3):598-604.