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Astrid Nehlig

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TOP 3
Astrid Nehlig
The neuroprotective effects of cocoa flavanol and its influence on cognitive performance.
Filiz Yilmaz Onat; Astrid Nehlig; Gilles van Luijtelaar; O Carter Snead
The involvement of limbic structures in typical and atypical absence epilepsy.
Katja Kobow; Wolfgang Löscher; Istvan Mody; Astrid Nehlig; Asla Pitkänen; Heidrun Potschka; David Prince; Stéphane Auvin; Frances Jensen; Alejandra Sierra; Michele Simonato; Jong M Rho
Finding a better drug for epilepsy: antiepileptogenesis targets.

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All Publications

2013: Astrid Nehlig
The neuroprotective effects of cocoa flavanol and its influence on cognitive performance.
British journal of clinical pharmacology 2013;75(3):716-27.
2013: Filiz Yilmaz Onat; Astrid Nehlig; Gilles van Luijtelaar; O Carter Snead
The involvement of limbic structures in typical and atypical absence epilepsy.
Epilepsy research 2013;103(2-3):111-23.
2012: Katja Kobow; Wolfgang Löscher; Istvan Mody; Astrid Nehlig; Asla Pitkänen; Heidrun Potschka; David Prince; Stéphane Auvin; Frances Jensen; Alejandra Sierra; Michele Simonato; Jong M Rho
Finding a better drug for epilepsy: antiepileptogenesis targets.
Epilepsia 2012;53(11):1868-76.
2012: Marco de Curtis; Astrid Nehlig; Jeffrey Noebels; Raman Sankar; Annamaria Vezzani
WONOEP XI: Workshop summary by the Scientific Organizing Committee.
Epilepsia 2012;53(7):1275-6.
2012: Thiago Vignoli; Rita de Cássia Sinigaglia Coimbra; Silvia Gomes Massironi; Maria da Graça Naffah Mazzacoratti; Astrid Nehlig; Eduardo Ferreira de Castro Neto; Daniele Suzete Persike; Iara Ribeiro Silva; M J S Fernandes
Consequences of pilocarpine-induced status epilepticus in immunodeficient mice.
Brain research 2012;1450():125-37.
2012: L Lecourtier; Brigitte Samama; A Schumacher; M-J Angst; M-C Antal; Jean-Christophe Cassel; Brigitte Cosquer; Arielle Ferrandon; Estelle Koning; Astrid Nehlig
Intact neurobehavioral development and dramatic impairments of procedural-like memory following neonatal ventral hippocampal lesion in rats.
Neuroscience 2012;207():110-23.
2012: Charles H Large; Astrid Nehlig; Raman Sankar; David M Sokal; Kevan E VanLandingham; Christopher S Crean; Martin J Gunthorpe; H Steve White
The spectrum of anticonvulsant efficacy of retigabine (ezogabine) in animal models: implications for clinical use.
Epilepsia 2012;53(3):425-36.
2011: Astrid Nehlig
Hippocampal MRI and other structural biomarkers: experimental approach to epileptogenesis.
Biomarkers in medicine 2011;5(5):585-97.
2011: Fernanda Elisa Rosim; Rebeca Padrão Amorim; Daniela Mara de Oliveira; Astrid Nehlig; Daniele Suzete Persike; M J S Fernandes
Differential neuroprotection by A(1) receptor activation and A(2A) receptor inhibition following pilocarpine-induced status epilepticus.
Epilepsy & behavior : E&B 2011;22(2):207-13.
2011: Yehezkel Ben-Ari; Roman Tyzio; Astrid Nehlig
Excitatory action of GABA on immature neurons is not due to absence of ketone bodies metabolites or other energy substrates.
Epilepsia 2011;52(9):1544-58.
2011: Claire Leroy; Luc Pellerin; Karin Pierre; Ian A Simpson; Susan J Vannucci; Astrid Nehlig
Temporal changes in mRNA expression of the brain nutrient transporters in the lithium-pilocarpine model of epilepsy in the immature and adult rat.
Neurobiology of disease 2011;43(3):588-97.
2011: Jennifer François; Katuschia Germe; Arielle Ferrandon; Estelle Koning; Astrid Nehlig
Carisbamate has powerful disease-modifying effects in the lithium-pilocarpine model of temporal lobe epilepsy.
Neuropharmacology 2011;61(1-2):313-28.
2011: Roman Tyzio; Camille Allene; Romain Nardou; Michel A Picardo; Sumii Yamamoto; Sudhir Sivakumaran; Maddalena D Caiati; Sylvain Rheims; marat MINLEBAEV; Mathieu Milh; Pascal Ferré; Rustem Khazipov; Jean-Louis Romette; Jean Lorquin; Rosa Cossart; Ilgam Khalilov; Astrid Nehlig; Enrico Cherubini; Yehezkel Ben-Ari
Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(1):34-45.
2011: Iara Ribeiro Silva; Astrid Nehlig; Fernanda Elisa Rosim; Thiago Vignoli; Daniele Suzete Persike; Arielle Ferrandon; R Sinigaglia-Coimbra; M J S Fernandes
The A1 receptor agonist R-Pia reduces the imbalance between cerebral glucose metabolism and blood flow during status epilepticus: could this mechanism be involved with neuroprotection?
Neurobiology of disease 2011;41(1):169-76.
2010: Benjamin Linard; Arielle Ferrandon; Estelle Koning; Astrid Nehlig; Emmanuel Raffo
Ketogenic diet exhibits neuroprotective effects in hippocampus but fails to prevent epileptogenesis in the lithium-pilocarpine model of mesial temporal lobe epilepsy in adult rats.
Epilepsia 2010;51(9):1829-36.
2010: Nadege Roche-Labarbe; Boubker Zaaimi; Mahdi Mahmoudzadeh; Viktoriya Osharina; Alice Wallois; Astrid Nehlig; Reinhard Grebe; Fabrice Wallois
NIRS-measured oxy- and deoxyhemoglobin changes associated with EEG spike-and-wave discharges in a genetic model of absence epilepsy: the GAERS.
Epilepsia 2010;51(8):1374-84.
2010: Jennifer François; Estelle Koning; Arielle Ferrandon; Guy Sandner; Astrid Nehlig
Metabolic activity in the brain of juvenile and adult rats with a neonatal ventral hippocampal lesion.
Hippocampus 2010;20(7):841-51.
2010: Karelle Benardais; Basem Kasem; Alice Couegnas; Brigitte Samama; Sebastien Fernandez; Christiane Schaeffer; Maria-Cristina Antal; Didier Job; Annie Schweitzer; Annie Andrieux; Anne Giersch; Astrid Nehlig; Nelly Boehm
Loss of STOP protein impairs peripheral olfactory neurogenesis.
PloS one 2010;5(9):e12753.
2010: Astrid Nehlig; Jean-Paul Armspach; Izzie J Namer
SPECT assessment of brain activation induced by caffeine: no effect on areas involved in dependence.
Dialogues in clinical neuroscience 2010;12(2):255-63.
2010: Astrid Nehlig
Is caffeine a cognitive enhancer?
Journal of Alzheimer's disease : JAD 2010;20 Suppl 1():S85-94.
2009: Emmanuel Raffo; Anne Pereira de Vasconcelos; Any Boehrer; Didier Desor; Astrid Nehlig
Neurobehavioral maturation of offspring from epileptic dams: study in the rat lithium-pilocarpine model.
Experimental neurology 2009;219(2):414-23.
2009: Stéphane Auvin; Natacha Porta; Astrid Nehlig; Cécile Lecointe; Louis Vallée; Régis Bordet
Inflammation in rat pups subjected to short hyperthermic seizures enhances brain long-term excitability.
Epilepsy research 2009;86(2-3):124-30.
2009: Jennifer François; Arielle Ferrandon; Estelle Koning; Marie-José Angst; Guy Sandner; Astrid Nehlig
Selective reorganization of GABAergic transmission in neonatal ventral hippocampal-lesioned rats.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2009;12(8):1097-110.
2009: Serge Chassagnon; Izzie J Namer; Jean-Paul Armspach; Astrid Nehlig; Philippe Kahane; Pierre Kehrli; Maria Paola Valenti; Edouard Hirsch
SPM analysis of ictal-interictal SPECT in mesial temporal lobe epilepsy: relationships between ictal semiology and perfusion changes.
Epilepsy research 2009;85(2-3):252-60.
2009: Astrid Nehlig; Franck Dufour; Marianne Klinger; Lisa B Willing; Ian A Simpson; Susan J Vannucci
The ketogenic diet has no effect on the expression of spike-and-wave discharges and nutrient transporters in genetic absence epilepsy rats from Strasbourg.
Journal of neurochemistry 2009;109 Suppl 1():207-13.
2009: Nihan Carçak; Arielle Ferrandon; Estelle Koning; rezzan gülhan aker; Osman Ozdemir; Filiz Yilmaz Onat; Astrid Nehlig
Effect of stage 2 kindling on local cerebral blood flow rates in rats with genetic absence epilepsy.
Epilepsia 2009;50(1):33-43.
2008: Nadege Roche-Labarbe; Boubker Zaaimi; Patrick Berquin; Astrid Nehlig; Reinhard Grebe; Fabrice Wallois
NIRS-measured oxy- and deoxyhemoglobin changes associated with EEG spike-and-wave discharges in children.
Epilepsia 2008;49(11):1871-80.
2008: Ryosuke Hanaya; Estelle Koning; Arielle Ferrandon; Astrid Nehlig
The role of the inherited genetic background on the consequences of lithium-pilocarpine status epilepticus: study in Genetic Absence Epilepsy Rats from Strasbourg and Wistar audiogenic rats.
Neurobiology of disease 2008;31(3):451-8.
2008: Ryosuke Hanaya; Estelle Koning; Arielle Ferrandon; Annie Schweitzer; Annie Andrieux; Astrid Nehlig
Deletion of the STOP gene, a microtubule stabilizing factor, leads only to discrete cerebral metabolic changes in mice.
Journal of neuroscience research 2008;86(4):813-20.
2008: Jennifer François; Any Boehrer; Astrid Nehlig
Effects of carisbamate (RWJ-333369) in two models of genetically determined generalized epilepsy, the GAERS and the audiogenic Wistar AS.
Epilepsia 2008;49(3):393-9.
2008: Emmanuel Raffo; Jennifer François; Arielle Ferrandon; Estelle Koning; Astrid Nehlig
Calorie-restricted ketogenic diet increases thresholds to all patterns of pentylenetetrazol-induced seizures: critical importance of electroclinical assessment.
Epilepsia 2008;49(2):320-8.
2007: Eiliv Brenner; Ursula Sonnewald; Annie Schweitzer; Annie Andrieux; Astrid Nehlig
Hypoglutamatergic activity in the STOP knockout mouse: a potential model for chronic untreated schizophrenia.
Journal of neuroscience research 2007;85(15):3487-93.
2007: Torun M Melø; Ursula Sonnewald; Irén Aina Bastholm; Astrid Nehlig
Astrocytes may play a role in the etiology of absence epilepsy: a comparison between immature GAERS not yet expressing seizures and adults.
Neurobiology of disease 2007;28(2):227-35.
2007: Astrid Nehlig; Jonathan A Coles
Cellular pathways of energy metabolism in the brain: is glucose used by neurons or astrocytes?
Glia 2007;55(12):1238-50.
2007: Ryosuke Hanaya; Nelly Boehm; Astrid Nehlig
Dissociation of the immunoreactivity of synaptophysin and GAP-43 during the acute and latent phases of the lithium-pilocarpine model in the immature and adult rat.
Experimental neurology 2007;204(2):720-32.
2007: Astrid Nehlig
What is animal experimentation telling us about new drug treatments of status epilepticus?
Epilepsia 2007;48 Suppl 8():78-81.
2007: Veronique Andre; Céline Dubé; Jennifer François; Claire Leroy; Marie-Aude Rigoulot; Catherine Roch; Izzie J Namer; Astrid Nehlig
Pathogenesis and pharmacology of epilepsy in the lithium-pilocarpine model.
Epilepsia 2007;48 Suppl 5():41-7.
2006: Jennifer François; Estelle Koning; Arielle Ferrandon; Astrid Nehlig
The combination of topiramate and diazepam is partially neuroprotective in the hippocampus but not antiepileptogenic in the lithium-pilocarpine model of temporal lobe epilepsy.
Epilepsy research 2006;72(2-3):147-63.
2006: Torun M Melø; Ursula Sonnewald; Monique Touret; Astrid Nehlig
Cortical glutamate metabolism is enhanced in a genetic model of absence epilepsy.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(12):1496-506.
2006: Brigitte Voutsinos-Porche; Estelle Koning; Yann Clément; Hervé Kaplan; Arielle Ferrandon; Jacques Motte; Astrid Nehlig
EAAC1 glutamate transporter expression in the rat lithium-pilocarpine model of temporal lobe epilepsy.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(11):1419-30.
2006: Carl E Stafstrom; Solomon L Moshe; John W Swann; Astrid Nehlig; Margaret P Jacobs; Philip A Schwartzkroin
Models of pediatric epilepsies: strategies and opportunities.
Epilepsia 2006;47(8):1407-14.
2006: Anne Pereira de Vasconcelos; Véronique Riban; Claude Wasterlain; Astrid Nehlig
Role of endothelial nitric oxide synthase in cerebral blood flow changes during kainate seizures: a genetic approach using knockout mice.
Neurobiology of disease 2006;23(1):219-27.
2006: Torun M Melø; Astrid Nehlig; Ursula Sonnewald
Neuronal-glial interactions in rats fed a ketogenic diet.
Neurochemistry international 2006;48(6-7):498-507.
2006: Serge Chassagnon; Veronique Andre; Estelle Koning; Arielle Ferrandon; Astrid Nehlig
Optimal window for ictal blood flow mapping. Insight from the study of discrete temporo-limbic seizures in rats.
Epilepsy research 2006;69(2):100-18.
2006: Astrid Nehlig; Gabrielle Rudolf; Claire Leroy; Marie-Aude Rigoulot; Ian A Simpson; Susan J Vannucci
Pentylenetetrazol-induced status epilepticus up-regulates the expression of glucose transporter mRNAs but not proteins in the immature rat brain.
Brain research 2006;1082(1):32-42.
2005: Torun M Melø; Astrid Nehlig; Ursula Sonnewald
Metabolism is normal in astrocytes in chronically epileptic rats: a (13)C NMR study of neuronal-glial interactions in a model of temporal lobe epilepsy.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(10):1254-64.
2005: Serge Chassagnon; Anne Pereira de Vasconcelos; Arielle Ferrandon; Estelle Koning; Christian Marescaux; Astrid Nehlig
Time course and mapping of cerebral perfusion during amygdala secondarily generalized seizures.
Epilepsia 2005;46(8):1178-87.
2005: Julien Detour; Henri Schroeder; Didier Desor; Astrid Nehlig
A 5-month period of epilepsy impairs spatial memory, decreases anxiety, but spares object recognition in the lithium-pilocarpine model in adult rats.
Epilepsia 2005;46(4):499-508.
2005: Anne Pereira de Vasconcelos; Viviane Bouilleret; Véronique Riban; Claude Wasterlain; Astrid Nehlig
Role of nitric oxide in cerebral blood flow changes during kainate seizures in mice: genetic and pharmacological approaches.
Neurobiology of disease 2005;18(2):270-81.
2004: Astrid Nehlig; Maria-Paola Valenti; Anne Thiriaux; Edouard Hirsch; Christian Marescaux; Izzie J Namer
Ictal and interictal perfusion variations measured by SISCOM analysis in typical childhood absence seizures.
Epileptic disorders : international epilepsy journal with videotape 2004;6(4):247-53.
2004: Brigitte Voutsinos-Porche; Estelle Koning; Hervé Kaplan; Arielle Ferrandon; Moncef Guenounou; Astrid Nehlig; Jacques Motte
Temporal patterns of the cerebral inflammatory response in the rat lithium-pilocarpine model of temporal lobe epilepsy.
Neurobiology of disease 2004;17(3):385-402.
2004: Emmanuel Raffo; Estelle Koning; Astrid Nehlig
Postnatal maturation of cytochrome oxidase and lactate dehydrogenase activity and age-dependent consequences of lithium-pilocarpine status epilepticus in the rat: a regional histoenzymology study.
Pediatric research 2004;56(4):647-55.
2004: Astrid Nehlig; Elisabeth Wittendorp-Rechenmann; Chang Dao Lam
Selective uptake of [14C]2-deoxyglucose by neurons and astrocytes: high-resolution microautoradiographic imaging by cellular 14C-trajectography combined with immunohistochemistry.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(9):1004-14.
2004: Véronique Riban; Anne Pereira de Vasconcelos; B T Phâm-Lê; Arielle Ferrandon; Christian Marescaux; Astrid Nehlig; Antoine Depaulis
Modifications of local cerebral glucose utilization in thalamic structures following injection of a dopaminergic agonist in the nucleus accumbens--involvement in antiepileptic effects?
Experimental neurology 2004;188(2):452-60.
2004: Claire Leroy; Pierrick Poisbeau; Florence Keller; Astrid Nehlig
Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy.
The Journal of physiology 2004;557(Pt 2):473-87.
2004: Agnès Duboc; Noëlle Hanoteau; Manuel Simonutti; Gabrielle Rudolf; Astrid Nehlig; José-Alain Sahel; Serge Picaud
Vigabatrin, the GABA-transaminase inhibitor, damages cone photoreceptors in rats.
Annals of neurology 2004;55(5):695-705.
2004: Astrid Nehlig
Brain uptake and metabolism of ketone bodies in animal models.
Prostaglandins, leukotrienes, and essential fatty acids 2004;70(3):265-75.
2004: Marie-Aude Rigoulot; Estelle Koning; Arielle Ferrandon; Astrid Nehlig
Neuroprotective properties of topiramate in the lithium-pilocarpine model of epilepsy.
The Journal of pharmacology and experimental therapeutics 2004;308(2):787-95.
2003: Marguerite Vergnes; Any Boehrer; Astrid Nehlig
Developmental characteristics of picrotoxin-induced convulsions in rats with genetic absence epilepsy.
Experimental neurology 2003;184(1):549-51.
2003: Claire Leroy; Catherine Roch; Estelle Koning; Izzie J Namer; Astrid Nehlig
In the lithium-pilocarpine model of epilepsy, brain lesions are not linked to changes in blood-brain barrier permeability: an autoradiographic study in adult and developing rats.
Experimental neurology 2003;182(2):361-72.
2003: Franck Dufour; Estelle Koning; Astrid Nehlig
Basal levels of metabolic activity are elevated in Genetic Absence Epilepsy Rats from Strasbourg (GAERS): measurement of regional activity of cytochrome oxidase and lactate dehydrogenase by histochemistry.
Experimental neurology 2003;182(2):346-52.
2003: Veronique Andre; Marie-Aude Rigoulot; Estelle Koning; Arielle Ferrandon; Astrid Nehlig
Long-term pregabalin treatment protects basal cortices and delays the occurrence of spontaneous seizures in the lithium-pilocarpine model in the rat.
Epilepsia 2003;44(7):893-903.
2003: Marie-Aude Rigoulot; Claire Leroy; Estelle Koning; Arielle Ferrandon; Astrid Nehlig
Prolonged low-dose caffeine exposure protects against hippocampal damage but not against the occurrence of epilepsy in the lithium-pilocarpine model in the rat.
Epilepsia 2003;44(4):529-35.
2003: Christophoros Nikou; Fabrice Heitz; Astrid Nehlig; Izzie J Namer; Jean-Paul Armspach
A robust statistics-based global energy function for the alignment of serially acquired autoradiographic sections.
Journal of neuroscience methods 2003;124(1):93-102.
2003: Marie-Aude Rigoulot; Any Boehrer; Astrid Nehlig
Effects of topiramate in two models of genetically determined generalized epilepsy, the GAERS and the Audiogenic Wistar AS.
Epilepsia 2003;44(1):14-9.
2003: Astrid Nehlig; Any Boehrer
Effects of remacemide in two models of genetically determined generalized epilepsy, the GAERS and the audiogenic Wistar AS.
Epilepsy research 2003;52(3):253-61.
2002: Catherine Roch; Claire Leroy; Astrid Nehlig; Izzie J Namer
Predictive value of cortical injury for the development of temporal lobe epilepsy in 21-day-old rats: an MRI approach using the lithium-pilocarpine model.
Epilepsia 2002;43(10):1129-36.
2002: Veronique Andre; Didier Henry; Astrid Nehlig
Dynamic variations of local cerebral blood flow in maximal electroshock seizures in the rat.
Epilepsia 2002;43(10):1120-8.
2002: Alexis Arzimanoglou; Edouard Hirsch; Astrid Nehlig; Pierre Castelnau; Pierre Gressens; Anne Pereira de Vasconcelos
Epilepsy and neuroprotection: an illustrated review.
Epileptic disorders : international epilepsy journal with videotape 2002;4(3):173-82.
2002: Astrid Nehlig; Céline Dubé; Estelle Koning
Status epilepticus induced by lithium-pilocarpine in the immature rat does not change the long-term susceptibility to seizures.
Epilepsy research 2002;51(1-2):189-97.
2002: Catherine Roch; Claire Leroy; Astrid Nehlig; Izzie J Namer
Magnetic resonance imaging in the study of the lithium-pilocarpine model of temporal lobe epilepsy in adult rats.
Epilepsia 2002;43(4):325-35.
2002: Magali Dutuit; Monique Touret; Raphaël Szymocha; Astrid Nehlig; Marie-Françoise Belin; Marianne Didier-Bazès
Decreased expression of glutamate transporters in genetic absence epilepsy rats before seizure occurrence.
Journal of neurochemistry 2002;80(6):1029-38.
2002: Anne Pereira de Vasconcelos; Arielle Ferrandon; Astrid Nehlig
Local cerebral blood flow during lithium-pilocarpine seizures in the developing and adult rat: role of coupling between blood flow and metabolism in the genesis of neuronal damage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(2):196-205.
2001: Franck Dufour; Katarzyna A Nalecz; Maciej J Nalecz; Astrid Nehlig
Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS: study of the leucine-glutamate cycle.
Journal of neuroscience research 2001;66(5):923-30.
2001: Veronique Andre; Arielle Ferrandon; Christian Marescaux; Astrid Nehlig
Vigabatrin protects against hippocampal damage but is not antiepileptogenic in the lithium-pilocarpine model of temporal lobe epilepsy.
Epilepsy research 2001;47(1-2):99-117.
2001: Franck Dufour; Katarzyna A Nalecz; Maciej J Nalecz; Astrid Nehlig
Modulation of absence seizures by branched-chain amino acids: correlation with brain amino acid concentrations.
Neuroscience research 2001;40(3):255-63.
2001: Céline Dubé; S Boyet; Christian Marescaux; Astrid Nehlig
Relationship between neuronal loss and interictal glucose metabolism during the chronic phase of the lithium-pilocarpine model of epilepsy in the immature and adult rat.
Experimental neurology 2001;167(2):227-41.
2001: Céline Dubé; M J da Silva Fernandes; Astrid Nehlig
Age-dependent consequences of seizures and the development of temporal lobe epilepsy in the rat.
Developmental neuroscience 2001;23(3):219-23.
2001: Veronique Andre; Christian Marescaux; Astrid Nehlig; J M Fritschy
Alterations of hippocampal GAbaergic system contribute to development of spontaneous recurrent seizures in the rat lithium-pilocarpine model of temporal lobe epilepsy.
Hippocampus 2001;11(4):452-68.
2000: Veronique Andre; Arielle Ferrandon; Christian Marescaux; Astrid Nehlig
Electroshocks delay seizures and subsequent epileptogenesis but do not prevent neuronal damage in the lithium-pilocarpine model of epilepsy.
Epilepsy research 2000;42(1):7-22.
2000: Viviane Bouilleret; Astrid Nehlig; Christian Marescaux; Izzie J Namer
Magnetic resonance imaging follow-up of progressive hippocampal changes in a mouse model of mesial temporal lobe epilepsy.
Epilepsia 2000;41(6):642-50.
2000: Magdalena Mac; Astrid Nehlig; M J Nałecz; K A Nałecz
Transport of alpha-ketoisocaproate in rat cerebral cortical neurons.
Archives of biochemistry and biophysics 2000;376(2):347-53.
2000: Anne Pereira de Vasconcelos; F Gizard; Christian Marescaux; Astrid Nehlig
Role of nitric oxide in pentylenetetrazol-induced seizures: age-dependent effects in the immature rat.
Epilepsia 2000;41(4):363-71.
2000: Sophie Reibel; Veronique Andre; Serge Chassagnon; G André; Christian Marescaux; Astrid Nehlig; Antoine Depaulis
Neuroprotective effects of chronic estradiol benzoate treatment on hippocampal cell loss induced by status epilepticus in the female rat.
Neuroscience letters 2000;281(2-3):79-82.
2000: Astrid Nehlig; S Boyet
Dose-response study of caffeine effects on cerebral functional activity with a specific focus on dependence.
Brain research 2000;858(1):71-7.
2000: Céline Dubé; S Boyet; Christian Marescaux; Astrid Nehlig
Progressive metabolic changes underlying the chronic reorganization of brain circuits during the silent phase of the lithium-pilocarpine model of epilepsy in the immature and adult Rat.
Experimental neurology 2000;162(1):146-57.
2000: Viviane Bouilleret; S Boyet; Christian Marescaux; Astrid Nehlig
Mapping of the progressive metabolic changes occurring during the development of hippocampal sclerosis in a model of mesial temporal lobe epilepsy.
Brain research 2000;852(2):255-62.
2000: Veronique Andre; Arielle Ferrandon; Christian Marescaux; Astrid Nehlig
The lesional and epileptogenic consequences of lithium-pilocarpine-induced status epilepticus are affected by previous exposure to isolated seizures: effects of amygdala kindling and maximal electroshocks.
Neuroscience 2000;99(3):469-81.
2000: Céline Dubé; Christian Marescaux; Astrid Nehlig
A metabolic and neuropathological approach to the understanding of plastic changes that occur in the immature and adult rat brain during lithium-pilocarpine-induced epileptogenesis.
Epilepsia 2000;41 Suppl 6():S36-43.
1999: Astrid Nehlig
Age-dependent pathways of brain energy metabolism: the suckling rat, a natural model of the ketogenic diet.
Epilepsy research 1999;37(3):211-21.
1999: Anne Pereira de Vasconcelos; Andrey Mazarati; Claude Wasterlain; Astrid Nehlig
Self-sustaining status epilepticus after a brief electrical stimulation of the perforant path: a 2-deoxyglucose study.
Brain research 1999;838(1-2):110-8.
1999: Viviane Bouilleret; V Ridoux; Antoine Depaulis; Christian Marescaux; Astrid Nehlig; G Le Gal La Salle
Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy.
Neuroscience 1999;89(3):717-29.
1999: M J Fernandes; Céline Dubé; S Boyet; Christian Marescaux; Astrid Nehlig
Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(2):195-209.
1999: N Pineau; C Charriaut-Marlangue; JE Motte; Astrid Nehlig
Pentylenetetrazol seizures induce cell suffering but not death in the immature rat brain.
Brain research. Developmental brain research 1999;112(1):139-44.
1999: Franck Dufour; Katarzyna A Nalecz; Maciej J Nalecz; Astrid Nehlig
Modulation of pentylenetetrazol-induced seizure activity by branched-chain amino acids and alpha-ketoisocaproate.
Brain research 1999;815(2):400-4.
1998: Céline Dubé; Veronique Andre; L Covolan; Arielle Ferrandon; Christian Marescaux; Astrid Nehlig
C-Fos, Jun D and HSP72 immunoreactivity, and neuronal injury following lithium-pilocarpine induced status epilepticus in immature and adult rats.
Brain research. Molecular brain research 1998;63(1):139-54.
1998: Henri Schroeder; A M Toniolo; Astrid Nehlig; Didier Desor
Long-term effects of early diazepam exposure on social differentiation in adult male rats subjected to the diving-for-food situation.
Behavioral neuroscience 1998;112(5):1209-17.
1998: Astrid Nehlig; Marguerite Vergnes; S Boyet; Christian Marescaux
Local cerebral glucose utilization in adult and immature GAERS.
Epilepsy research 1998;32(1-2):206-12.
1998: Astrid Nehlig; Marguerite Vergnes; S Boyet; Christian Marescaux
Metabolic activity is increased in discrete brain regions before the occurrence of spike-and-wave discharges in weanling rats with genetic absence epilepsy.
Brain research. Developmental brain research 1998;108(1-2):69-75.
1998: V André; N Pineau; JE Motte; Christian Marescaux; Astrid Nehlig
Mapping of neuronal networks underlying generalized seizures induced by increasing doses of pentylenetetrazol in the immature and adult rat: a c-Fos immunohistochemical study.
The European journal of neuroscience 1998;10(6):2094-106.
1998: JE Motte; M J Fernandes; T Z Baram; Astrid Nehlig
Spatial and temporal evolution of neuronal activation, stress and injury in lithium-pilocarpine seizures in adult rats.
Brain research 1998;793(1-2):61-72.
1998: Anne Pereira de Vasconcelos; Christian Marescaux; Astrid Nehlig
Age-dependent regulation of seizure activity by nitric oxide in the developing rat.
Brain research. Developmental brain research 1998;107(2):315-9.
1997: JE Motte; M J da Silva Fernandes; Christian Marescaux; Astrid Nehlig
Effects of pentylenetetrazol-induced status epilepticus on c-Fos and HSP72 immunoreactivity in the immature rat brain.
Brain research. Molecular brain research 1997;50(1-2):79-84.
1997: Henri Schroeder; A C Humbert; Didier Desor; Astrid Nehlig
Long-term consequences of neonatal exposure to diazepam on cerebral glucose utilization, learning, memory and anxiety.
Brain research 1997;766(1-2):142-52.
1997: M Bachowska-Mac; Astrid Nehlig; M J Nałecz; K A Nałecz
Transport of alpha-ketoisocaproate in neuroblastoma NB-2a cells.
Biochemical and biophysical research communications 1997;237(1):63-7.
1997: Anne Pereira de Vasconcelos; Marguerite Vergnes; S Boyet; Christian Marescaux; Astrid Nehlig
Forebrain metabolic activation induced by the repetition of audiogenic seizures in Wistar rats.
Brain research 1997;762(1-2):114-20.
1997: Edouard Hirsch; L Danober; S Simler; Anne Pereira de Vasconcelos; B Maton; Astrid Nehlig; Christian Marescaux; Marguerite Vergnes
The amygdala is critical for seizure propagation from brainstem to forebrain.
Neuroscience 1997;77(4):975-84.
1997: Henri Schroeder; A M Toniolo; Didier Desor; Astrid Nehlig
[Chronic prenatal exposure to diazepam, brain metabolism and behavior: long-term consequences in the adult rat].
L'Encéphale 1997;23(2):131-41.
1996: Astrid Nehlig; Anne Pereira de Vasconcelos
The model of pentylenetetrazol-induced status epilepticus in the immature rat: short- and long-term effects.
Epilepsy research 1996;26(1):93-103.
1996: Astrid Nehlig; Anne Pereira de Vasconcelos; Marguerite Vergnes; S Boyet; Christian Marescaux
Interictal cerebral metabolic levels in Wistar rats sensitive to audiogenic seizures.
Brain research 1996;724(1):97-102.
1996: Astrid Nehlig
Respective roles of glucose and ketone bodies as substrates for cerebral energy metabolism in the suckling rat.
Developmental neuroscience 1996;18(5-6):426-33.
1996: C Roger; Violette Koziel; P Vert; Astrid Nehlig
Autoradiographic mapping of local cerebral permeability to bilirubin in immature rats: effects of hyperbilirubinemia.
Pediatric research 1996;39(1):64-71.
1996: Astrid Nehlig; Marguerite Vergnes; R Waydelich; Edouard Hirsch; R Charbonne; Christian Marescaux; J Seylaz
Absence seizures induce a decrease in cerebral blood flow: human and animal data.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(1):147-55.
1995: V Padou; S Boyet; Astrid Nehlig
Changes in transport of [14C] alpha-aminoisobutyric acid across the blood-brain barrier during pentylenetetrazol-induced status epilepticus in the immature rat.
Epilepsy research 1995;22(3):175-83.
1995: C Roger; Violette Koziel; P Vert; Astrid Nehlig
Mapping of the consequences of bilirubin exposure in the immature rat: local cerebral metabolic rates for glucose during moderate and severe hyperbilirubinemia.
Early human development 1995;43(2):133-44.
1995: C Roger; Violette Koziel; P Vert; Astrid Nehlig
Regional cerebral metabolic consequences of bilirubin in rat depend upon post-gestational age at the time of hyperbilirubinemia.
Brain research. Developmental brain research 1995;87(2):194-202.
1995: Anne Pereira de Vasconcelos; S Boyet; Violette Koziel; Astrid Nehlig
Effects of pentylenetetrazol-induced status epilepticus on local cerebral blood flow in the developing rat.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(2):270-83.
1995: Astrid Nehlig; Marguerite Vergnes; E Hirsch; S Boyet; Violette Koziel; Christian Marescaux
Mapping of cerebral blood flow changes during audiogenic seizures in Wistar rats: effect of kindling.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(2):259-69.
1995: Henri Schroeder; A C Humbert; Violette Koziel; Didier Desor; Astrid Nehlig
Behavioral and metabolic consequences of neonatal exposure to diazepam in rat pups.
Experimental neurology 1995;131(1):53-63.
1994: Henri Schroeder; A Nolte; S Boyet; Violette Koziel; Astrid Nehlig
Short- and long-term effects of neonatal diazepam exposure on local cerebral glucose utilization in the rat.
Brain research 1994;660(1):144-53.
1994: H Schroeder; A Collignon; L Uttscheid; Anne Pereira de Vasconcelos; Astrid Nehlig
Effects of early chronic diazepam treatment on incorporation of glucose and beta-hydroxybutyrate into cerebral amino acids: relation to undernutrition.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1994;12(5):471-84.
1994: Astrid Nehlig; Jean-Luc Daval; S Boyet
Effects of selective adenosine A1 and A2 receptor agonists and antagonists on local rates of energy metabolism in the rat brain.
European journal of pharmacology 1994;258(1-2):57-66.
1994: Astrid Nehlig
Effects of respiratory stimulants on cerebral metabolism and blood flow.
Biology of the neonate 1994;65(3-4):258-64.
1993: A Bilger; Astrid Nehlig
Regional cerebral blood flow response to acute hypoxia changes with postnatal age in the rat.
Brain research. Developmental brain research 1993;76(2):197-205.
1993: C Roger; Violette Koziel; P Vert; Astrid Nehlig
Effects of bilirubin infusion on local cerebral glucose utilization in the immature rat.
Brain research. Developmental brain research 1993;76(1):115-30.
1993: Astrid Nehlig; Marguerite Vergnes; Christian Marescaux; S Boyet
Cerebral energy metabolism in rats with genetic absence epilepsy is not correlated with the pharmacological increase or suppression of spike-wave discharges.
Brain research 1993;618(1):1-8.
1993: Astrid Nehlig
Imaging and the ontogeny of brain metabolism.
Baillière's clinical endocrinology and metabolism 1993;7(3):627-42.
1992: Anne Pereira de Vasconcelos; G el Hamdi; P Vert; Astrid Nehlig
An experimental model of generalized seizures for the measurement of local cerebral glucose utilization in the immature rat. II. Mapping of brain metabolism using the quantitative [14C]2-deoxyglucose technique.
Brain research. Developmental brain research 1992;69(2):243-59.
1992: G el Hamdi; A P de Vasconcelos; P Vert; Astrid Nehlig
An experimental model of generalized seizures for the measurement of local cerebral glucose utilization in the immature rat. I. Behavioral characterization and determination of lumped constant.
Brain research. Developmental brain research 1992;69(2):233-42.
1992: Henri Schroeder; I Dumont; S Boyet; E Mocaër; Astrid Nehlig
Effects of the acute administration of a new trimethylxanthine derivative, S 9977-2, on local cerebral blood flow and glucose utilization in the rat.
European journal of pharmacology 1992;220(2-3):217-29.
1992: G el Hamdi; M J Boutroy; Astrid Nehlig
Effects of pentylenetetrazol-induced seizures on dopamine and norepinephrine levels and on glucose utilization in various brain regions of the developing rat.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1992;10(4):301-11.
1992: A Bilger; Astrid Nehlig
Quantitative histochemical changes in enzymes involved in energy metabolism in the rat brain during postnatal development. II. Glucose-6-phosphate dehydrogenase and beta-hydroxybutyrate dehydrogenase.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1992;10(2):143-52.
1992: L Bômont; A Bilger; S Boyet; P Vert; Astrid Nehlig
Acute hypoxia induces specific changes in local cerebral glucose utilization at different postnatal ages in the rat.
Brain research. Developmental brain research 1992;66(1):33-45.
1992: Astrid Nehlig; Marguerite Vergnes; Christian Marescaux; S Boyet
Mapping of cerebral energy metabolism in rats with genetic generalized nonconvulsive epilepsy.
Journal of neural transmission. Supplementum 1992;35():141-53.
1992: Jean-Luc Daval; Anne Pereira de Vasconcelos; G el Hamdi; M C Werck; Astrid Nehlig
Quantitative autoradiographic measurements of functional changes induced by generalized seizures in the developing rat brain: central adenosine and benzodiazepine receptors and local cerebral glucose utilization.
Epilepsy research. Supplement 1992;9():83-92; discussion 93.
1991: Astrid Nehlig; Anne Pereira de Vasconcelos; S Boyet
[Application of quantitative autoradiography to the measurement of brain function activity in rats during post-natal development].
Bulletin de l'Association des anatomistes 1991;75(229):101-4.
1991: Astrid Nehlig; S Boyet; Anne Pereira de Vasconcelos
Autoradiographic measurement of local cerebral beta-hydroxybutyrate uptake in the rat during postnatal development.
Neuroscience 1991;40(3):871-8.
1991: Jean-Luc Daval; Astrid Nehlig; F Nicolas
Physiological and pharmacological properties of adenosine: therapeutic implications.
Life sciences 1991;49(20):1435-53.
1991: Jean-Luc Daval; M C Werck; Astrid Nehlig; Anne Pereira de Vasconcelos
Quantitative autoradiographic study of the postnatal development of adenosine A1 receptors and their coupling to G proteins in the rat brain.
Neuroscience 1991;40(3):841-51.
1991: Astrid Nehlig; Marguerite Vergnes; Christian Marescaux; S Boyet; Béatrice Lannes
Local cerebral glucose utilization in rats with petit mal-like seizures.
Annals of neurology 1991;29(1):72-7.
1991: H Schroeder; L Bomont; Astrid Nehlig
Influence of early chronic phenobarbital treatment on cerebral arteriovenous differences of glucose and ketone bodies in the developing rat.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1991;9(5):453-61.
1991: A Bilger; Astrid Nehlig
Quantitative histochemical changes in enzymes involved in energy metabolism in the rat brain during postnatal development. I. Cytochrome oxidase and lactate dehydrogenase.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1991;9(6):545-53.
1991: Jean-Luc Daval; M C Werck; Astrid Nehlig; Anne Pereira de Vasconcelos
Quantitative autoradiographic study of the postnatal development of benzodiazepine binding sites and their coupling to GABA receptors in the rat brain.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1991;9(4):307-20.
1990: Anne Pereira de Vasconcelos; S Boyet; Astrid Nehlig
Consequences of chronic phenobarbital treatment on local cerebral glucose utilization in the developing rat.
Brain research. Developmental brain research 1990;53(2):168-78.
1990: A Pereira de Vasconcelos; C Colin; Didier Desor; M Divry; Astrid Nehlig
Influence of early neonatal phenobarbital exposure on cerebral energy metabolism and behavior.
Experimental neurology 1990;108(2):176-87.
1990: Astrid Nehlig; Anne Pereira de Vasconcelos; I Dumont; S Boyet
Effects of caffeine, L-phenylisopropyladenosine and their combination on local cerebral blood flow in the rat.
European journal of pharmacology 1990;179(3):271-80.
1989: Astrid Nehlig; Anne Pereira de Vasconcelos; S Boyet
Postnatal changes in local cerebral blood flow measured by the quantitative autoradiographic [14C]iodoantipyrine technique in freely moving rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(5):579-88.
1989: Henri Schroeder; S Boyet; Astrid Nehlig
Effects of caffeine and doxapram perfusion on local cerebral glucose utilization in conscious rats.
European journal of pharmacology 1989;167(2):245-54.
1988: Astrid Nehlig; Anne Pereira de Vasconcelos; A Collignon; S Boyet
Comparative effects of caffeine and L-phenylisopropyladenosine on local cerebral glucose utilization in the rat.
European journal of pharmacology 1988;157(1):1-11.
1988: Astrid Nehlig; A P de Vasconcelos; S Boyet
Quantitative autoradiographic measurement of local cerebral glucose utilization in freely moving rats during postnatal development.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(7):2321-33.
1987: Anne Pereira de Vasconcelos; H Schroeder; Astrid Nehlig
Effects of early chronic phenobarbital treatment on the maturation of energy metabolism in the developing rat brain. II. Incorporation of beta-hydroxybutyrate into amino acids.
Brain research 1987;433(2):231-6.
1987: Astrid Nehlig; Jean-Luc Daval; Anne Pereira de Vasconcelos; S Boyet
Caffeine-diazepam interaction and local cerebral glucose utilization in the conscious rat.
Brain research 1987;419(1-2):272-8.
1986: Astrid Nehlig; Jean-Luc Daval; S Boyet; P Vert
Comparative effects of acute and chronic administration of caffeine on local cerebral glucose utilization in the conscious rat.
European journal of pharmacology 1986;129(1-2):93-103.