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Nathan Zaccai

Research Profile

Procedures

X Ray Crystallography

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Genes & Molecular Sequences

Amino Acid Sequences

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Publications

TOP 3
Thomas H Sharp; Andrew R Thomson; Paul Verkade; R Leo Brady; Marc Bruning; Judith Mantell; Richard B Sessions; Nathan R Zaccai; Derek N Woolfson
Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design.
Jordan M Fletcher; Andrew R Thomson; Thomas L Vincent; Craig T Armstrong; Gail J Bartlett; Paula J Booth; Aimee L Boyle; R Leo Brady; Elizabeth H C Bromley; Marc Bruning; Nathan R Zaccai; Derek N Woolfson
A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology.
Elena Galfré; Stephen O'Neill; Samantha J Pitt; Mano Sitsapesan; Krasimira Tsaneva-Atanasova; Elisa Venturi; Nathan R Zaccai; Rebecca Sitsapesan
FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6.

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All Publications

2012: Thomas H Sharp; Andrew R Thomson; Paul Verkade; R Leo Brady; Marc Bruning; Judith Mantell; Richard B Sessions; Nathan R Zaccai; Derek N Woolfson
Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(33):13266-71.
2012: Jordan M Fletcher; Andrew R Thomson; Thomas L Vincent; Craig T Armstrong; Gail J Bartlett; Paula J Booth; Aimee L Boyle; R Leo Brady; Elizabeth H C Bromley; Marc Bruning; Nathan R Zaccai; Derek N Woolfson
A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology.
ACS synthetic biology 2012;1(6):240-50.
2012: Elena Galfré; Stephen O'Neill; Samantha J Pitt; Mano Sitsapesan; Krasimira Tsaneva-Atanasova; Elisa Venturi; Nathan R Zaccai; Rebecca Sitsapesan
FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6.
PloS one 2012;7(2):e31956.
2011: Nathan R Zaccai; Gail J Bartlett; Paula J Booth; Aimee L Boyle; R Leo Brady; Marc Bruning; Bertie Chi; Noah Linden; Richard B Sessions; Andrew R Thomson; Derek N Woolfson
A de novo peptide hexamer with a mutable channel.
Nature chemical biology 2011;7(12):935-41.
2011: Christopher Agnew; Massimo Antognozzi; Elena Borodina; Nicholas M Burton; David K Cole; Rebecca Conners; James A Vicary; Mumtaz Virji; Nathan R Zaccai; R Leo Brady
Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(37):15174-8.
2008: Simon J Hanslip; Nathan R Zaccai; Anton P J Middelberg; Robert J Falconer
Intrinsic fluorescence as an analytical probe of virus-like particle assembly and maturation.
Biochemical and biophysical research communications 2008;375(3):351-5.
2008: Richard Stewart; Lele Song; Simon M Carter; Charalambos Sigalas; Nathan R Zaccai; Venkateswarlu Kanamarlapudi; Manjunatha B Bhat; Hiroshi Takeshima; Rebecca Sitsapesan
Single-channel characterization of the rabbit recombinant RyR2 reveals a novel inactivation property of physiological concentrations of ATP.
The Journal of membrane biology 2008;222(2):65-77.
2008: Nathan R Zaccai; Lester G Carter; Nick S Berrow; Sarah Sainsbury; Joanne E Nettleship; thomas walter; Karl Harlos; Raymond J Owens; Keith S Wilson; David I Stuart; Robert M Esnouf
Crystal structure of a 3-oxoacyl-(acylcarrier protein) reductase (BA3989) from Bacillus anthracis at 2.4-A resolution.
Proteins 2008;70(2):562-7.
2007: Nathan R Zaccai; Kamran Yunus; Sinéad M Matthews; Adrian C Fisher; Robert J Falconer
Refolding of a membrane protein in a microfluidics reactor.
European biophysics journal : EBJ 2007;36(6):581-8.
2007: Nathan R Zaccai; Andrew P May; Robert Robinson; Leslie D Burtnick; Paul R Crocker; Reinhard Brossmer; Soerge Kelm; E Yvonne Jones
Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin.
Journal of molecular biology 2007;365(5):1469-79.
2006: K Au; Nick S Berrow; Elena V Blagova; Ian W Boucher; M P Boyle; James A Brannigan; Lester G Carter; T Dierks; G Folkers; Rosa Grenha; Karl Harlos; Robert Kaptein; Anne K Kalliomaa; Vladimir M Levdikov; Christoph Meier; N Milioti; O Moroz; Axel Muller; Raymond J Owens; N Rzechorzek; Sarah Sainsbury; David I Stuart; thomas walter; David G Waterman; Anthony J Wilkinson; Keith S Wilson; Nathan R Zaccai; Robert M Esnouf; Mark J Fogg
Application of high-throughput technologies to a structural proteomics-type analysis of Bacillus anthracis.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 10):1267-75.
2006: Simon J Hanslip; Nathan R Zaccai; Anton P J Middelberg; Robert J Falconer
Assembly of human papillomavirus type-16 virus-like particles: multifactorial study of assembly and competing aggregation.
Biotechnology progress 2006;22(2):554-60.
2004: Thil Batuwangala; Dawn Shepherd; Stephan D Gadola; Kevin J C Gibson; Nathan R Zaccai; Alan Fersht; Gurdyal S Besra; Vincenzo Cerundolo; E Yvonne Jones
The crystal structure of human CD1b with a bound bacterial glycolipid.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2382-8.
2003: Stephan D Gadola; Anastasios Karadimitris; Nathan R Zaccai; Mariolina Salio; Nicolas Dulphy; Dawn Shepherd; E Yvonne Jones; Vincenzo Cerundolo
Generation of CD1 tetramers as a tool to monitor glycolipid-specific T cells.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2003;358(1433):875-7.
2003: Nathan R Zaccai; Katsumi Maenaka; Taeko Maenaka; Paul R Crocker; Reinhard Brossmer; Soerge Kelm; E Yvonne Jones
Structure-guided design of sialic acid-based Siglec inhibitors and crystallographic analysis in complex with sialoadhesin.
Structure (London, England : 1993) 2003;11(5):557-67.
2002: Stephan D Gadola; Nathan R Zaccai; Karl Harlos; Dawn Shepherd; Julio C Castro-Palomino; Gerd Ritter; Richard R Schmidt; E Yvonne Jones; Vincenzo Cerundolo
Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Nature immunology 2002;3(8):721-6.
2002: Rosemary J Boyton; Nathan R Zaccai; E Yvonne Jones; Daniel M Altmann
CD4 T cells selected by antigen under Th2 polarizing conditions favor an elongated TCR alpha chain complementarity-determining region 3.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1018-27.
1999: Paul Bowness; Nathan R Zaccai; Lucy A Bird; E Yvonne Jones
HLA-B27 and disease pathogenesis: new structural and functional insights.
Expert reviews in molecular medicine 1999;1999():1-10.
1999: Katsumi Maenaka; T Juji; T Nakayama; Jessica R Wyer; George F Gao; Taeko Maenaka; Nathan R Zaccai; A Kikuchi; T Yabe; K Tokunaga; K Tadokoro; David I Stuart; E Yvonne Jones; Philip van der Merwe
Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties.
The Journal of biological chemistry 1999;274(40):28329-34.