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Mikko Juhani Lammi

Research Profile

Anatomy

Chemicals & Drugs

Living Beings

Cattle
Dogs

Phenomena

Disorders

Osteoarthritis

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Publications

TOP 3
H J Pulkkinen; L Rieppo; T S Silvast; Virpi Tiitu; Juha Töyräs; Piia Valonen; Jukka S Jurvelin; Mikko Juhani Lammi; Ilkka Kiviranta
Repair of osteochondral defects with recombinant human type II collagen gel and autologous chondrocytes in rabbit.
Feng Zhang; C Duan; Xiong Guo; S Wu; H Yu; Mikko Juhani Lammi
Identification of differentially expressed genes and pathways between primary osteoarthritis and endemic osteoarthritis (Kashin-Beck disease).
Siru M Turunen; Arto Koistinen; Mikko Juhani Lammi; Simo Saarakkala; Rami K Korhonen
Hypotonic challenge modulates cell volumes differently in the superficial zone of intact articular cartilage and cartilage explant.

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2013: H J Pulkkinen; L Rieppo; T S Silvast; Virpi Tiitu; Juha Töyräs; Piia Valonen; Jukka S Jurvelin; Mikko Juhani Lammi; Ilkka Kiviranta
Repair of osteochondral defects with recombinant human type II collagen gel and autologous chondrocytes in rabbit.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2013;21(3):481-90.
2013: Feng Zhang; C Duan; Xiong Guo; S Wu; H Yu; Mikko Juhani Lammi
Identification of differentially expressed genes and pathways between primary osteoarthritis and endemic osteoarthritis (Kashin-Beck disease).
Scandinavian journal of rheumatology 2013;42(1):71-9.
2012: Siru M Turunen; Arto Koistinen; Mikko Juhani Lammi; Simo Saarakkala; Rami K Korhonen
Hypotonic challenge modulates cell volumes differently in the superficial zone of intact articular cartilage and cartilage explant.
Biomechanics and modeling in mechanobiology 2012;11(5):665-75.
2012: T Virén; Y P Zheng; RR van Weeren; P A J Brama; Harold Brommer; A Brünott; Y P Huang; Jukka S Jurvelin; Ilkka Kiviranta; Mikko Juhani Lammi; A Linjama; H Pulkkinen; Simo Saarakkala; Virpi Tiitu; Juha Töyräs
Comparison of ultrasound and optical coherence tomography techniques for evaluation of integrity of spontaneously repaired horse cartilage.
Journal of medical engineering & technology 2012;36(3):185-92.
2012: Chengjuan Qu; Janne H Ylärinne; Heli Lindeberg; Mikko Juhani Lammi
Five percent oxygen tension is not beneficial for neocartilage formation in scaffold-free cell cultures.
Cell and tissue research 2012;348(1):109-17.
2012: M J Turunen; Jukka S Jurvelin; Mikko Juhani Lammi; Juha Töyräs; Rami K Korhonen
Hyperosmolaric contrast agents in cartilage tomography may expose cartilage to overload-induced cell death.
Journal of biomechanics 2012;45(3):497-503.
2012: Shuang Wang; Xiong Guo; Xiao-ming Wu; Mikko Juhani Lammi
Genome-wide gene expression analysis suggests an important role of suppressed immunity in pathogenesis of Kashin-Beck disease.
PloS one 2012;7(1):e28439.
2011: Wei-Juan Ma; An-Guo Sun; Yue-Xiang Yu; Xiong Guo; Jian-Wen Hu; Jiang-Tao Liu; Rui-Yu Liu; Mikko Juhani Lammi
Proteomic changes in articular cartilage of human endemic osteoarthritis in China.
Proteomics 2011;11(14):2881-90.
2011: Raimo Pöllänen; Anna-Maria Tikkanen; Mikko Juhani Lammi; Reijo Lappalainen
The effect of loading and material on the biomechanical properties and vitality of bovine cartilage in vitro.
Journal of applied biomaterials & biomechanics : JABB 2011;9(1):47-53.
2010: H J Pulkkinen; Virpi Tiitu; Piia Valonen; Jukka S Jurvelin; Mikko Juhani Lammi; Ilkka Kiviranta
Engineering of cartilage in recombinant human type II collagen gel in nude mouse model in vivo.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2010;18(8):1077-87.
2010: Anu Olkku; Jarkko J Leskinen; Mikko Juhani Lammi; Kullervo Hynynen; Anitta Mahonen
Ultrasound-induced activation of Wnt signaling in human MG-63 osteoblastic cells.
Bone 2010;47(2):320-30.
2010: Tuomas Virén; Simo Saarakkala; Jukka S Jurvelin; Hertta J Pulkkinen; Virpi Tiitu; Piia Valonen; Ilkka Kiviranta; Mikko Juhani Lammi; Juha Töyräs
Quantitative evaluation of spontaneously and surgically repaired rabbit articular cartilage using intra-articular ultrasound method in situ.
Ultrasound in medicine & biology 2010;36(5):833-9.
2010: Sami Myllymaa; Katja Myllymaa; Hannu Korhonen; Mikko Juhani Lammi; Virpi Tiitu; Reijo Lappalainen
Surface characterization and in vitro biocompatibility assessment of photosensitive polyimide films.
Colloids and surfaces. B, Biointerfaces 2010;76(2):505-11.
2010: Chen Duan; Xiong Guo; Xiao-Dong Zhang; Han-Jie Yu; Hua Yan; Ying Gao; Wei-Juan Ma; Zong-Qiang Gao; Peng Xu; Mikko Juhani Lammi
Comparative analysis of gene expression profiles between primary knee osteoarthritis and an osteoarthritis endemic to Northwestern China, Kashin-Beck disease.
Arthritis and rheumatism 2010;62(3):771-80.
2010: Teemu K Långsjö; Anna I Vasara; Mika M Hyttinen; Mikko Juhani Lammi; Antti Kaukinen; Heikki J Helminen; Ilkka Kiviranta
Quantitative analysis of collagen network structure and fibril dimensions in cartilage repair with autologous chondrocyte transplantation.
Cells, tissues, organs 2010;192(6):351-60.
2009: Petro Julkunen; T Harjula; J Iivarinen; J Marjanen; K Seppänen; T Närhi; Jari P A Arokoski; Mikko Juhani Lammi; P A Brama; Jukka S Jurvelin; Heikki J Helminen
Biomechanical, biochemical and structural correlations in immature and mature rabbit articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2009;17(12):1628-38.
2009: Katja Myllymaa; Sami Myllymaa; Tapani A Pakkanen; Hanna Saarenpää; Mika Suvanto; Virpi Tiitu; Hannu Korhonen; Mikko Juhani Lammi; Reijo Lappalainen
Improved adherence and spreading of Saos-2 cells on polypropylene surfaces achieved by surface texturing and carbon nitride coating.
Journal of materials science. Materials in medicine 2009;20(11):2337-47.
2009: Cheng-Juan Qu; Teemu Pöytäkangas; Marjo Jauhiainen; Seppo Auriola; Mikko Juhani Lammi
Glucosamine sulphate does not increase extracellular matrix production at low oxygen tension.
Cell and tissue research 2009;337(1):103-11.
2009: Pauno Lötjönen; Petro Julkunen; Juha Töyräs; Mikko Juhani Lammi; Jukka S Jurvelin; Heikki J Nieminen
Strain-dependent modulation of ultrasound speed in articular cartilage under dynamic compression.
Ultrasound in medicine & biology 2009;35(7):1177-84.
2009: T S Silvast; Jukka S Jurvelin; Antti Aula; Mikko Juhani Lammi; Juha Töyräs
Contrast agent-enhanced computed tomography of articular cartilage: association with tissue composition and properties.
Acta radiologica (Stockholm, Sweden : 1987) 2009;50(1):78-85.
2009: T S Silvast; J S Jurvelin; Mikko Juhani Lammi; J Töyräs
pQCT study on diffusion and equilibrium distribution of iodinated anionic contrast agent in human articular cartilage--associations to matrix composition and integrity.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2009;17(1):26-32.
2009: W Z Wang; X Guo; C Duan; W J Ma; Y G Zhang; P Xu; Z Q Gao; Z F Wang; H Yan; Y F Zhang; Y X Yu; J C Chen; Mikko Juhani Lammi
Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2009;17(1):83-90.
2008: H J Pulkkinen; V Tiitu; Piia Valonen; E-R Hamalainen; Mikko Juhani Lammi; I Kiviranta
Recombinant human type II collagen as a material for cartilage tissue engineering.
The International journal of artificial organs 2008;31(11):960-9.
2008: Weizhuo Wang; Xiong Guo; Junchang Chen; Peng Xu; Mikko Juhani Lammi
Morphology and phenotype expression of types I, II, III, and X collagen and MMP-13 of chondrocytes cultured from articular cartilage of Kashin-Beck Disease.
The Journal of rheumatology 2008;35(4):696-702.
2008: Virpi Tiitu; H J Pulkkinen; Piia Valonen; O Kiviranta; T Kiekara; Ilkka Kiviranta; Mikko Juhani Lammi
Recombinant human collagens as scaffold materials for chondrocyte cultures.
Bio-medical materials and engineering 2008;18(4-5):225-9.
2008: Virpi Tiitu; H J Pulkkinen; Piia Valonen; O Pulliainen; Minna Kellomäki; Mikko Juhani Lammi; Ilkka Kiviranta
Bioreactor improves the growth and viability of chondrocytes in the knitted poly-L,D-lactide scaffold.
Biorheology 2008;45(3-4):539-46.
2008: Jarkko J Leskinen; Hannu M Karjalainen; Anu Olkku; Kullervo Hynynen; Anitta Mahonen; Mikko Juhani Lammi
Genome-wide microarray analysis of MG-63 osteoblastic cells exposed to ultrasound.
Biorheology 2008;45(3-4):345-54.
2008: Juha Piltti; Jukka Häyrinen; Hannu M Karjalainen; Mikko Juhani Lammi
Proteomics of chondrocytes with special reference to phosphorylation changes of proteins in stretched human chondrosarcoma cells.
Biorheology 2008;45(3-4):323-35.
2008: Petro Julkunen; Wouter Wilson; Jukka S Jurvelin; Jarno Rieppo; Cheng-Juan Qu; Mikko Juhani Lammi; Rami K Korhonen
Stress-relaxation of human patellar articular cartilage in unconfined compression: prediction of mechanical response by tissue composition and structure.
Journal of biomechanics 2008;41(9):1978-86.
2007: J Sierpowska; Mikko Juhani Lammi; Mikko A Hakulinen; Jukka S Jurvelin; Reijo Lappalainen; Juha Töyräs
Effect of human trabecular bone composition on its electrical properties.
Medical engineering & physics 2007;29(8):845-52.
2007: Ossi Riekkinen; Mikko A Hakulinen; Mikko Juhani Lammi; Jukka S Jurvelin; Antti Aula; Juha Töyräs
Acoustic properties of trabecular bone--relationships to tissue composition.
Ultrasound in medicine & biology 2007;33(9):1438-44.
2007: Cheng-Juan Qu; M Jauhiainen; S Auriola; Heikki J Helminen; Mikko Juhani Lammi
Effects of glucosamine sulfate on intracellular UDP-hexosamine and UDP-glucuronic acid levels in bovine primary chondrocytes.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2007;15(7):773-9.
2007: Outi Pulliainen; Anna I Vasara; Mika M Hyttinen; Virpi Tiitu; Piia Valonen; Minna Kellomäki; Jukka S Jurvelin; Lars Peterson; Anders Lindahl; Ilkka Kiviranta; Mikko Juhani Lammi
Poly-L-D-lactic acid scaffold in the repair of porcine knee cartilage lesions.
Tissue engineering 2007;13(6):1347-55.
2007: Antti Aula; Jukka S Jurvelin; Miika T Nieminen; Mikko Juhani Lammi; Juha Töyräs
Contrast agent enhanced pQCT of articular cartilage.
Physics in medicine and biology 2007;52(4):1209-19.
2007: Cheng-Juan Qu; Jarno Rieppo; Mika M Hyttinen; Mikko Juhani Lammi; Ilkka Kiviranta; Jatta Kurkijärvi; Jukka S Jurvelin; Juha Töyräs
Human articular cartilage proteoglycans are not undersulfated in osteoarthritis.
Connective tissue research 2007;48(1):27-33.
2006: Anna I Vasara; Mika M Hyttinen; O Pulliainen; Mikko Juhani Lammi; Jukka S Jurvelin; L Peterson; A Lindahl; Heikki J Helminen; Ilkka Kiviranta
Immature porcine knee cartilage lesions show good healing with or without autologous chondrocyte transplantation.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2006;14(10):1066-74.
2006: Kai Kaarniranta; Tapio Ihanamäki; Janne Sahlman; Hertta Pulkkinen; Hannu Uusitalo; Machiko Arita; Raija Tammi; Mikko Juhani Lammi; Heikki J Helminen
A mouse model for Stickler's syndrome: ocular phenotype of mice carrying a targeted heterozygous inactivation of type II (pro)collagen gene (Col2a1).
Experimental eye research 2006;83(2):297-303.
2006: Mikko Juhani Lammi; Jukka Häyrinen; Anitta Mahonen
Proteomic analysis of cartilage- and bone-associated samples.
Electrophoresis 2006;27(13):2687-701.
2006: Cheng-Juan Qu; Hannu M Karjalainen; Heikki J Helminen; Mikko Juhani Lammi
The lack of effect of glucosamine sulphate on aggrecan mRNA expression and (35)S-sulphate incorporation in bovine primary chondrocytes.
Biochimica et biophysica acta 2006;1762(4):453-9.
2006: Milla Kopakkala-Tani; Jarkko J Leskinen; Hannu M Karjalainen; Tero Karjalainen; Kullervo Hynynen; Juha Töyräs; Jukka S Jurvelin; Mikko Juhani Lammi
Ultrasound stimulates proteoglycan synthesis in bovine primary chondrocytes.
Biorheology 2006;43(3-4):271-82.
2006: Hertta Pulkkinen; Virpi Tiitu; Eveliina Lammentausta; Mikko S Laasanen; Eija-Riitta Hämäläinen; Ilkka Kiviranta; Mikko Juhani Lammi
Cellulose sponge as a scaffold for cartilage tissue engineering.
Bio-medical materials and engineering 2006;16(4 Suppl):S29-35.
2005: Mikko Juhani Lammi
Does oral glucosamine prevent the loss of proteoglycans in a rabbit model of osteoarthritis? Comment on the article by Tiraloche et al.
Arthritis and rheumatism 2005;52(11):3680; author reply 3680-81.
2005: Kai Kaarniranta; Tuomas Ryhänen; Hannu M Karjalainen; Mikko Juhani Lammi; Tiina Suuronen; Anne Huhtala; Matti Kontkanen; Markku Teräsvirta; Hannu Uusitalo; Antero Salminen
Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells.
Neuroscience letters 2005;382(1-2):185-90.
2005: Kai Kaarniranta; Tuomas Ryhänen; Reijo K Sironen; Tiina Suuronen; Mika A Elo; Hannu M Karjalainen; Mikko Juhani Lammi; Markku Teräsvirta; Hannu Uusitalo; Antero Salminen
Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells.
Brain research. Molecular brain research 2005;137(1-2):126-31.
2005: Mika A Elo; Kai Kaarniranta; Heikki J Helminen; Mikko Juhani Lammi
Hsp90 inhibitor geldanamycin increases hsp70 mRNA stabilisation but fails to activate HSF1 in cells exposed to hydrostatic pressure.
Biochimica et biophysica acta 2005;1743(1-2):115-9.
2005: Mika A Elo; Hannu M Karjalainen; Reijo K Sironen; Leena Valmu; Nicholas T Redpath; Gareth J Browne; Nisse Kalkkinen; Heikki J Helminen; Mikko Juhani Lammi
High hydrostatic pressure inhibits the biosynthesis of eukaryotic elongation factor-2.
Journal of cellular biochemistry 2005;94(3):497-507.
2004: Mikko Juhani Lammi; Cheng-Juan Qu; Mikko S Laasanen; Simo Saarakkala; Jarno Rieppo; Jukka S Jurvelin; Juha Töyräs
Undersulfated chondroitin sulfate does not increase in osteoarthritic cartilage.
The Journal of rheumatology 2004;31(12):2449-53.
2004: Janne Sahlman; Marja T Pitkänen; Darwin J Prockop; Machiko Arita; Shi-Wu Li; Heikki J Helminen; Teemu K Långsjö; Kaija Puustjärvi; Mikko Juhani Lammi
A human COL2A1 gene with an Arg519Cys mutation causes osteochondrodysplasia in transgenic mice.
Arthritis and rheumatism 2004;50(10):3153-60.
2004: Reijo K Sironen; Hannu M Karjalainen; Kari Törrönen; Mika A Elo; Mika M Hyttinen; Heikki J Helminen; Mikko Juhani Lammi
Reticulon 4 in chondrocytic cells: barosensitivity and intracellular localization.
The international journal of biochemistry & cell biology 2004;36(8):1521-31.
2004: M Kopakkala-Tani; Mika A Elo; Reijo K Sironen; Heikki J Helminen; Mikko Juhani Lammi
High hydrostatic pressure induces ERK and PI3 kinase phosphorylation in human HCS-2/8 chondrosarcoma cells.
Cellular and molecular biology (Noisy-le-Grand, France) 2004;50(4):485-90.
2004: Olli Mäkelä; Mikko Juhani Lammi; Hannele Uusitalo; Minna Viitanen; Mika M Hyttinen; Jukka S Jurvelin; Eero Vuorio; Heikki J Helminen; Riitta-Mari Tulamo
Effect of radiosynovectomy with holmium-166 ferric hydroxide macroaggregate on adult equine cartilage.
The Journal of rheumatology 2004;31(2):321-8.
2004: Mikko Juhani Lammi
Current perspectives on cartilage and chondrocyte mechanobiology.
Biorheology 2004;41(3-4):593-6.
2004: Mikko Juhani Lammi; Mika A Elo; Reijo K Sironen; Hannu M Karjalainen; Kai Kaarniranta; Heikki J Helminen
Hydrostatic pressure-induced changes in cellular protein synthesis.
Biorheology 2004;41(3-4):309-13.
2004: Anna I Vasara; Mika M Hyttinen; Mikko Juhani Lammi; PE Lammi; Teemu K Långsjö; Anders Lindahl; Lars Peterson; Minna Kellomäki; Yrjö T Konttinen; Heikki J Helminen; Ilkka Kiviranta
Subchondral bone reaction associated with chondral defect and attempted cartilage repair in goats.
Calcified tissue international 2004;74(1):107-14.
2003: Simo Saarakkala; Mikko S Laasanen; Jukka S Jurvelin; Kari Törrönen; Mikko Juhani Lammi; Reijo Lappalainen; Juha Töyräs
Ultrasound indentation of normal and spontaneously degenerated bovine articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2003;11(9):697-705.
2003: Sanna Pasonen-Seppänen; Susanna Karvinen; Kari Törrönen; Juha M T Hyttinen; Tiina Jokela; Mikko Juhani Lammi; Markku Tammi; Raija Tammi
EGF upregulates, whereas TGF-beta downregulates, the hyaluronan synthases Has2 and Has3 in organotypic keratinocyte cultures: correlations with epidermal proliferation and differentiation.
The Journal of investigative dermatology 2003;120(6):1038-44.
2003: Juha Töyräs; Mikko S Laasanen; Simo Saarakkala; Mikko Juhani Lammi; Jarno Rieppo; Jatta Kurkijärvi; Reijo Lappalainen; Jukka S Jurvelin
Speed of sound in normal and degenerated bovine articular cartilage.
Ultrasound in medicine & biology 2003;29(3):447-54.
2003: Kai Kaarniranta; Roope K Sihvola; Antero Salminen; Mikko Juhani Lammi; Markku Teräsvirta; Matti Kontkanen
[Age-related macular degeneration--a difficult problem for the patient and for the ophthalmologist].
Duodecim; lääketieteellinen aikakauskirja 2003;119(10):935-42.
2003: Olli Mäkelä; Mikko Juhani Lammi; H Uusitalo; Mika M Hyttinen; Eero Vuorio; Heikki J Helminen; Riitta-Mari Tulamo
Analysis of lapine cartilage matrix after radiosynovectomy with holmium-166 ferric hydroxide macroaggregate.
Annals of the rheumatic diseases 2003;62(1):43-9.
2003: Mika A Elo; Reijo K Sironen; Hannu M Karjalainen; Kai Kaarniranta; Heikki J Helminen; Mikko Juhani Lammi
Specific induction of heat shock protein 90beta by high hydrostatic pressure.
Biorheology 2003;40(1-3):141-6.
2003: Hannu M Karjalainen; Reijo K Sironen; Mika A Elo; Kai Kaarniranta; Masaharu Takigawa; Heikki J Helminen; Mikko Juhani Lammi
Gene expression profiles in chondrosarcoma cells subjected to cyclic stretching and hydrostatic pressure. A cDNA array study.
Biorheology 2003;40(1-3):93-100.
2003: Kai Kaarniranta; Mika A Elo; Reijo K Sironen; Hannu M Karjalainen; Heikki J Helminen; Mikko Juhani Lammi
Stress responses of mammalian cells to high hydrostatic pressure.
Biorheology 2003;40(1-3):87-92.
2002: PE Lammi; Mikko Juhani Lammi; Mika M Hyttinen; HE Panula; Ilkka Kiviranta; H J Helminen
Site-specific immunostaining for type X collagen in noncalcified articular cartilage of canine stifle knee joint.
Bone 2002;31(6):690-6.
2002: Kirsi Rilla; Mikko Juhani Lammi; Reijo K Sironen; Kari Törrönen; Merja Luukkonen; Vincent C Hascall; Ronald J Midura; Mika M Hyttinen; Jukka Pelkonen; Markku Tammi; Raija Tammi
Changed lamellipodial extension, adhesion plaques and migration in epidermal keratinocytes containing constitutively expressed sense and antisense hyaluronan synthase 2 (Has2) genes.
Journal of cell science 2002;115(Pt 18):3633-43.
2002: Reijo K Sironen; Hannu M Karjalainen; Mika A Elo; Kai Kaarniranta; Kari Törrönen; Masaharu Takigawa; Heikki J Helminen; Mikko Juhani Lammi
cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressure.
Biochimica et biophysica acta 2002;1591(1-3):45-54.
2002: Kai Kaarniranta; Niku K J Oksala; Hannu M Karjalainen; Tiina Suuronen; Lea Sistonen; Heikki J Helminen; Antero Salminen; Mikko Juhani Lammi
Neuronal cells show regulatory differences in the hsp70 gene response.
Brain research. Molecular brain research 2002;101(1-2):136-40.
2002: Reijo K Sironen; Hannu M Karjalainen; Kari Törrönen; Mika A Elo; Kai Kaarniranta; Masaharu Takigawa; Heikki J Helminen; Mikko Juhani Lammi
High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis.
Biorheology 2002;39(1-2):111-7.
2001: Janne Sahlman; RI Inkinen; T Hirvonen; Mikko Juhani Lammi; PE Lammi; Jenni Nieminen; T Lapveteläinen; Darwin J Prockop; Machiko Arita; Shi-Wu Li; Mika M Hyttinen; Heikki J Helminen; Kaija Puustjärvi
Premature vertebral endplate ossification and mild disc degeneration in mice after inactivation of one allele belonging to the Col2a1 gene for Type II collagen.
Spine 2001;26(23):2558-65.
2001: Mika M Hyttinen; Jari P A Arokoski; Jyrki Parkkinen; Mikko Juhani Lammi; T Lapveteläinen; K Mauranen; K Király; Markku Tammi; Heikki J Helminen
Age matters: collagen birefringence of superficial articular cartilage is increased in young guinea-pigs but decreased in older animals after identical physiological type of joint loading.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(8):694-701.
2001: M M Espanha; PE Lammi; Mika M Hyttinen; Mikko Juhani Lammi; Heikki J Helminen
Extracellular matrix composition of full-thickness defect repair tissue is little influenced by exercise in rat articular cartilage.
Connective tissue research 2001;42(2):97-109.
2001: J P Pienimaki; Kirsi Rilla; C Fulop; Reijo K Sironen; Susanna Karvinen; S Pasonen; Mikko Juhani Lammi; Raija Tammi; Vincent C Hascall; Markku Tammi
Epidermal growth factor activates hyaluronan synthase 2 in epidermal keratinocytes and increases pericellular and intracellular hyaluronan.
The Journal of biological chemistry 2001;276(23):20428-35.
2001: PE Lammi; Mikko Juhani Lammi; Raija Tammi; H J Helminen; M M Espanha
Strong hyaluronan expression in the full-thickness rat articular cartilage repair tissue.
Histochemistry and cell biology 2001;115(4):301-8.
2001: Kai Kaarniranta; Niku K J Oksala; Mikko Juhani Lammi; Heikki J Helminen; Lea Sistonen
[From research of cellular stress to various clinical break through innovations?].
Duodecim; lääketieteellinen aikakauskirja 2001;117(22):2266-72.
2001: Jari P A Arokoski; Mikko Juhani Lammi; Mika M Hyttinen; Ilkka Kiviranta; Jyrki Parkkinen; J S Jurvelin; Markku Tammi; Heikki J Helminen
[Etiopathogenesis of osteoarthritis].
Duodecim; lääketieteellinen aikakauskirja 2001;117(16):1617-26; quiz 1626, 1679.
2001: Kai Kaarniranta; C I Holmberg; Mikko Juhani Lammi; John E Eriksson; Lea Sistonen; Heikki J Helminen
Primary chondrocytes resist hydrostatic pressure-induced stress while primary synovial cells and fibroblasts show modified Hsp70 response.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(1):7-13.
2000: Mika A Elo; Reijo K Sironen; Kai Kaarniranta; S Auriola; Heikki J Helminen; Mikko Juhani Lammi
Differential regulation of stress proteins by high hydrostatic pressure, heat shock, and unbalanced calcium homeostasis in chondrocytic cells.
Journal of cellular biochemistry 2000;79(4):610-9.
2000: Szabolcs Felszeghy; Krisztina Holló; László Módis; Mikko Juhani Lammi
Type X collagen in human enamel development: a possible role in mineralization.
Acta odontologica Scandinavica 2000;58(4):171-6.
2000: Kai Kaarniranta; C I Holmberg; Heikki J Helminen; John E Eriksson; Lea Sistonen; Mikko Juhani Lammi
Protein synthesis is required for stabilization of hsp70 mRNA upon exposure to both hydrostatic pressurization and elevated temperature.
FEBS letters 2000;475(3):283-6.
2000: M O Jortikka; Jyrki Parkkinen; RI Inkinen; J Kärner; Hannu Järveläinen; Lassi Nelimarkka; Markku Tammi; Mikko Juhani Lammi
The role of microtubules in the regulation of proteoglycan synthesis in chondrocytes under hydrostatic pressure.
Archives of biochemistry and biophysics 2000;374(2):172-80.
2000: E Kääpä; W Wang; T E Takala; M Poussa; Y T Konttinen; Mikko Juhani Lammi; Heikki Vanharanta
Elevated protein content and prolyl 4-hydroxylase activity in severely degenerated human annulus fibrosus.
Connective tissue research 2000;41(2):93-9.
2000: Heikki J Helminen; Mika M Hyttinen; Mikko Juhani Lammi; Jari P A Arokoski; T Lapveteläinen; Jukka S Jurvelin; Ilkka Kiviranta; Markku Tammi
Regular joint loading in youth assists in the establishment and strengthening of the collagen network of articular cartilage and contributes to the prevention of osteoarthrosis later in life: a hypothesis.
Journal of bone and mineral metabolism 2000;18(5):245-57.
2000: Reijo K Sironen; Mika A Elo; Kai Kaarniranta; Heikki J Helminen; Mikko Juhani Lammi
Transcriptional activation in chondrocytes submitted to hydrostatic pressure.
Biorheology 2000;37(1-2):85-93.
1999: RI Inkinen; Mikko Juhani Lammi; UM Agren; Raija Tammi; Kaija Puustjärvi; Markku Tammi
Hyaluronan distribution in the human and canine intervertebral disc and cartilage endplate.
The Histochemical journal 1999;31(9):579-87.
1999: J Haapala; Jari P A Arokoski; Mika M Hyttinen; Mikko Juhani Lammi; Markku Tammi; Vuokko Kovanen; Heikki J Helminen; Ilkka Kiviranta
Remobilization does not fully restore immobilization induced articular cartilage atrophy.
Clinical orthopaedics and related research 1999;(362):218-29.
1998: PE Lammi; RI Inkinen; Klaus von der Mark; Kaija Puustjärvi; Jari P A Arokoski; Mika M Hyttinen; Mikko Juhani Lammi
Localization of type X collagen in the intervertebral disc of mature beagle dogs.
Matrix biology : journal of the International Society for Matrix Biology 1998;17(6):449-53.
1998: I Eerola; Heli Salminen; PE Lammi; Mikko Juhani Lammi; Klaus von der Mark; Eero Vuorio; Anna-Marja Säämänen
Type X collagen, a natural component of mouse articular cartilage: association with growth, aging, and osteoarthritis.
Arthritis and rheumatism 1998;41(7):1287-95.
1998: Kai Kaarniranta; Mika A Elo; Reijo K Sironen; Mikko Juhani Lammi; M B Goldring; John E Eriksson; Lea Sistonen; Heikki J Helminen
Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2319-24.
1998: RI Inkinen; Mikko Juhani Lammi; S Lehmonen; Kaija Puustjärvi; E Kääpä; Markku Tammi
Relative increase of biglycan and decorin and altered chondroitin sulfate epitopes in the degenerating human intervertebral disc.
The Journal of rheumatology 1998;25(3):506-14.
1998: N A Visser; M H M T de Koning; Mikko Juhani Lammi; T Häkkinen; M Tammi; G P van Kampen
Increase of decorin content in articular cartilage following running.
Connective tissue research 1998;37(3-4):295-302.
1997: Frank Beier; SI Vornehm; Ernst Pöschl; Klaus von der Mark; Mikko Juhani Lammi
Localization of silencer and enhancer elements in the human type X collagen gene.
Journal of cellular biochemistry 1997;66(2):210-8.
1997: Jyrki Parkkinen; Mikko Juhani Lammi; UM Agren; Markku Tammi; Tuomo A Keinänen; T Hyvönen; T O Eloranta
Polyamine-dependent alterations in the structure of microfilaments, Golgi apparatus, endoplasmic reticulum, and proteoglycan synthesis in BHK cells.
Journal of cellular biochemistry 1997;66(2):165-74.
1997: Lassi Nelimarkka; V Kainulainen; E Schönherr; S Moisander; M Jortikka; Mikko Juhani Lammi; Klaus Elenius; M Jalkanen; Hannu Järveläinen
Expression of small extracellular chondroitin/dermatan sulfate proteoglycans is differentially regulated in human endothelial cells.
The Journal of biological chemistry 1997;272(19):12730-7.
1997: M O Jortikka; RI Inkinen; Markku Tammi; Jyrki Parkkinen; J Haapala; Ilkka Kiviranta; Heikki J Helminen; Mikko Juhani Lammi
Immobilisation causes longlasting matrix changes both in the immobilised and contralateral joint cartilage.
Annals of the rheumatic diseases 1997;56(4):255-61.
1996: F Beier; I Eerola; E Vuorio; Phyllis LuValle; E Reichenberger; W Bertling; Klaus von der Mark; Mikko Juhani Lammi
Variability in the upstream promoter and intron sequences of the human, mouse and chick type X collagen genes.
Matrix biology : journal of the International Society for Matrix Biology 1996;15(6):415-22.
1996: J Haapala; Mikko Juhani Lammi; RI Inkinen; Jyrki Parkkinen; UM Agren; Jari P A Arokoski; Ilkka Kiviranta; Heikki J Helminen; Markku Tammi
Coordinated regulation of hyaluronan and aggrecan content in the articular cartilage of immobilized and exercised dogs.
The Journal of rheumatology 1996;23(9):1586-93.
1996: F Beier; Mikko Juhani Lammi; W Bertling; Klaus von der Mark
Transcriptional regulation of the human type X collagen gene expression.
Annals of the New York Academy of Sciences 1996;785():209-11.
1996: Jyrki Parkkinen; Tomi P Häkkinen; S Savolainen; C Wang; Raija Tammi; UM Agren; Mikko Juhani Lammi; Jari P A Arokoski; Heikki J Helminen; Markku Tammi
Distribution of hyaluronan in articular cartilage as probed by a biotinylated binding region of aggrecan.
Histochemistry and cell biology 1996;105(3):187-94.
1996: K Király; Mikko Juhani Lammi; Jari P A Arokoski; T Lapveteläinen; Markku Tammi; Heikki J Helminen; Ilkka Kiviranta
Safranin O reduces loss of glycosaminoglycans from bovine articular cartilage during histological specimen preparation.
The Histochemical journal 1996;28(2):99-107.
1995: Jyrki Parkkinen; Mikko Juhani Lammi; RI Inkinen; M Jortikka; Markku Tammi; I Virtanen; Heikki J Helminen
Influence of short-term hydrostatic pressure on organization of stress fibers in cultured chondrocytes.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1995;13(4):495-502.
1995: J Karppinen; RI Inkinen; Eeva Kääpä; Mikko Juhani Lammi; Markku Tammi; S Holm; H Vanharanta
Effects of tiaprofenic acid and indomethacin on proteoglycans in the degenerating porcine intervertebral disc.
Spine 1995;20(10):1170-7.
1994: Mikko Juhani Lammi; RI Inkinen; Jyrki Parkkinen; Tomi P Häkkinen; M Jortikka; L O Nelimarkka; Hannu Järveläinen; Markku Tammi
Expression of reduced amounts of structurally altered aggrecan in articular cartilage chondrocytes exposed to high hydrostatic pressure.
The Biochemical journal 1994;304 ( Pt 3)():723-30.
1994: Eeva Kääpä; S Holm; RI Inkinen; Mikko Juhani Lammi; Markku Tammi; H Vanharanta
Proteoglycan chemistry in experimentally injured porcine intervertebral disk.
Journal of spinal disorders 1994;7(4):296-306.
1994: Kaija Puustjärvi; Mikko Juhani Lammi; Heikki J Helminen; RI Inkinen; Markku Tammi
Proteoglycans in the intervertebral disc of young dogs following strenuous running exercise.
Connective tissue research 1994;30(3):225-40.
1993: Kaija Puustjärvi; Mikko Juhani Lammi; Ilkka Kiviranta; Heikki J Helminen; Markku Tammi
Proteoglycan synthesis in canine intervertebral discs after long-distance running training.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1993;11(5):738-46.
1993: Mikko Juhani Lammi; Tomi P Häkkinen; Jyrki Parkkinen; Mika M Hyttinen; M Jortikka; Heikki J Helminen; Markku Tammi
Adaptation of canine femoral head articular cartilage to long distance running exercise in young beagles.
Annals of the rheumatic diseases 1993;52(5):369-77.
1993: Jyrki Parkkinen; Mikko Juhani Lammi; Alpo Pelttari; Heikki J Helminen; Markku Tammi; I Virtanen
Altered Golgi apparatus in hydrostatically loaded articular cartilage chondrocytes.
Annals of the rheumatic diseases 1993;52(3):192-8.
1993: Kaija Puustjärvi; Mikko Juhani Lammi; Ilkka Kiviranta; Heikki J Helminen; Markku Tammi
Flat bed scanner in the quantitative assay of 35SO4-incorporation by X-ray film autoradiography of intervertebral disc sections.
Histochemistry 1993;99(1):67-73.
1993: Mikko Juhani Lammi; Tomi P Häkkinen; Jyrki Parkkinen; Mika M Hyttinen; M Jortikka; Heikki J Helminen; Markku Tammi
Effects of long-term running exercise on canine femoral head articular cartilage.
Agents and actions. Supplements 1993;39():95-9.
1993: Anna-Marja Säämänen; Kaija Puustjärvi; K Ilves; Mikko Juhani Lammi; Ilkka Kiviranta; Jukka S Jurvelin; Heikki J Helminen; Markku Tammi
Effect of running exercise on proteoglycans and collagen content in the intervertebral disc of young dogs.
International journal of sports medicine 1993;14(1):48-51.
1993: Jyrki Parkkinen; J Ikonen; Mikko Juhani Lammi; J Laakkonen; Markku Tammi; Heikki J Helminen
Effects of cyclic hydrostatic pressure on proteoglycan synthesis in cultured chondrocytes and articular cartilage explants.
Archives of biochemistry and biophysics 1993;300(1):458-65.
1993: M Jortikka; Mikko Juhani Lammi; Jyrki Parkkinen; R Lahtinen; Markku Tammi
A high sensitivity dot-blot assay for proteoglycans by cuprolinic blue precipitation.
Connective tissue research 1993;29(4):263-72.
1992: Jyrki Parkkinen; Mikko Juhani Lammi; Heikki J Helminen; Markku Tammi
Local stimulation of proteoglycan synthesis in articular cartilage explants by dynamic compression in vitro.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1992;10(5):610-20.
1992: Heikki J Helminen; Anna-Marja Säämänen; Jukka S Jurvelin; Ilkka Kiviranta; Jyrki Parkkinen; Mikko Juhani Lammi; Markku Tammi
[The effect of loading on articular cartilage].
Duodecim; lääketieteellinen aikakauskirja 1992;108(12):1097-107.
1991: Mikko Juhani Lammi; Markku Tammi
Autoradiographic quantitation of radiolabeled proteoglycans.
Journal of biochemical and biophysical methods 1991;22(4):301-10.
1990: Jyrki Parkkinen; K Paukkonen; E Pesonen; Mikko Juhani Lammi; S Markkanen; Heikki J Helminen; Markku Tammi
Quantitation of autoradiographic grains in different zones of articular cartilage with image analyzer.
Histochemistry 1990;93(3):241-5.
1989: Jyrki Parkkinen; Mikko Juhani Lammi; S Karjalainen; J Laakkonen; E Hyvärinen; A Tiihonen; Heikki J Helminen; Markku Tammi
A mechanical apparatus with microprocessor controlled stress profile for cyclic compression of cultured articular cartilage explants.
Journal of biomechanics 1989;22(11-12):1285-91.
1988: Mikko Juhani Lammi; Markku Tammi
Densitometric assay of nanogram quantities of proteoglycans precipitated on nitrocellulose membrane with Safranin O.
Analytical biochemistry 1988;168(2):352-7.