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Simon Lovestone

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TOP 3
Latha Velayudhan; John F Powell; Megan Pritchard; Petroula Proitsi; Simon Lovestone
Smell identification function as a severity and progression marker in Alzheimer's disease.
Francesca Mangialasche; Patrizia Mecocci; J-S Muehlboeck; Andrew Simmons; Hilkka Soininen; Christian Spenger; Roberto Tarducci; M Tsolaki; Bruno Vellas; L-O Wahlund; E Westman; M Baglioni; Roberta Cecchetti; P Floridi; Gianni Gobbi; Miia Kivipelto; I Kłoszewska; Simon Lovestone
Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol.
Carlos Aguilar; Iwona Kloszewska; Simon Lovestone; Patrizia Mecocci; J-Sebastian Muehlboeck; Andrew Simmons; Hilkka Soininen; Christian Spenger; Magda Tsolaki; Bruno Vellas; Eric Westman; Lars-Olof Wahlund
Different multivariate techniques for automated classification of MRI data in Alzheimer's disease and mild cognitive impairment.

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All Publications

2013: Latha Velayudhan; John F Powell; Megan Pritchard; Petroula Proitsi; Simon Lovestone
Smell identification function as a severity and progression marker in Alzheimer's disease.
International psychogeriatrics / IPA 2013;25(7):1157-66.
2013: Francesca Mangialasche; Patrizia Mecocci; J-S Muehlboeck; Andrew Simmons; Hilkka Soininen; Christian Spenger; Roberto Tarducci; M Tsolaki; Bruno Vellas; L-O Wahlund; E Westman; M Baglioni; Roberta Cecchetti; P Floridi; Gianni Gobbi; Miia Kivipelto; I Kłoszewska; Simon Lovestone
Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol.
Journal of internal medicine 2013;273(6):602-21.
2013: Carlos Aguilar; Iwona Kloszewska; Simon Lovestone; Patrizia Mecocci; J-Sebastian Muehlboeck; Andrew Simmons; Hilkka Soininen; Christian Spenger; Magda Tsolaki; Bruno Vellas; Eric Westman; Lars-Olof Wahlund
Different multivariate techniques for automated classification of MRI data in Alzheimer's disease and mild cognitive impairment.
Psychiatry research 2013;212(2):89-98.
2013: Madhav Thambisetty; Alan B Zonderman; Andrew B Singleton; Yang An; Lori L Beason-Held; Luigi Ferrucci; Dena G Hernandez; Michael A Kraut; Simon Lovestone; Michael Nalls; Susan M Resnick
Alzheimer risk variant CLU and brain function during aging.
Biological psychiatry 2013;73(5):399-405.
2013: Richard Killick; T R Hughes; B P Morgan; Simon Lovestone
Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH.
Neuroscience letters 2013;533():96-9.
2013: Latha Velayudhan; Bruno Vellas; Eric Westman; Angela Hodges; Iwona Kłoszewska; Simon Lovestone; Patrizia Mecocci; J-Sebastian Muehlboeck; John Powell; Petroula Proitsi; Andrew Simmons; Hilkka Soininen; Christian Spenger; Magda Tsolaki
Entorhinal cortex thickness predicts cognitive decline in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;33(3):755-66.
2013: Katie Lunnon; Michelle K Lupton; Patrizia Mecocci; Petroula Proitsi; Martina Sattlecker; Andrew Simmons; Hilkka Soininen; Magda Tsolaki; Bruno Vellas; Giovanni Coppola; Richard Dobson; Simon J Furney; Daniel Geschwind; Angela Hodges; Caroline Johnston; Iwona Kłoszewska; Anbarasu Lourdusamy; Simon Lovestone
A blood gene expression marker of early Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;33(3):737-53.
2013: Simon Lovestone
Trait, state, and mechanism: looking back, looking forward, and understanding why.
Journal of Alzheimer's disease : JAD 2013;33 Suppl 1():S23-33.
2012: Francesca Mangialasche; Patrizia Mecocci; Martina Pigliautile; Andrew Simmons; Hilkka Soininen; Magda Tsolaki; Bruno Vellas; Weili Xu; Mauro Baglioni; Roberta Cecchetti; Egidia Costanzi; Sara Ercolani; Miia Kivipelto; Iwona Kloszewska; Simon Lovestone
Tocopherols and tocotrienols plasma levels are associated with cognitive impairment.
Neurobiology of aging 2012;33(10):2282-90.
2012: Yawu Liu; Simon Lovestone; Patrizia Mecocci; Sebastian Muehlboeck; Teemu Paajanen; Andrew Simmons; Tomasz Sobow; Hilkka Soininen; Christian Spenger; Magda Tsolaki; Bruno Vellas; Lars-Olof Wahlund; Eric Westman; Andrew Aitken; Valtteri Julkunen
Education increases reserve against Alzheimer's disease--evidence from structural MRI analysis.
Neuroradiology 2012;54(9):929-38.
2012: Anbarasu Lourdusamy; Simon Lovestone; Katie Lunnon; Patrizia Mecocci; Sally K Nelson; Stephan Newhouse; John Powell; Petra Proitsi; Hilkka Soininen; Alex Stewart; Magda Tsolaki; Bruno Vellas; Stephen Williams; Richard Dobson; Angela Hodges; Iwona Kloszewska
Identification of cis-regulatory variation influencing protein abundance levels in human plasma.
Human molecular genetics 2012;21(16):3719-26.
2012: Chantal Bazenet; Simon Lovestone
Plasma biomarkers for Alzheimer's disease: much needed but tough to find.
Biomarkers in medicine 2012;6(4):441-54.
2012: Hui Shi; Steven G Younkin; Olivia Belbin; Kristelle Brown; Minerva M Carrasquillo; Alison Goate; Noor Kalsheker; Simon Lovestone; Christopher Medway; Kevin Morgan; Peter Passmore; John Powell; Petroula Proitsi
Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).
Neurobiology of aging 2012;33(8):1849.e5-18.
2012: Petroula Proitsi; David C Rubinsztein; Hilkka Soininen; Stephen Todd; Magda Tsolaki; Bruno Velas; Julie Williams; Janet Johnson; Megan Pritchard; Carol Brayne; David Craig; Makrina Daniilidou; Frank Dudbridge; Michael Gill; Gillian Hamilton; Denise Harold; Paul Hollingworth; Iwona Kloszewska; Brian Lawlor; Kathryn Lord; Simon Lovestone; Michelle K Lupton; Belinda M Martin; Bernadette McGuinness; Patrizia Mecocci; Peter Passmore; John F Powell
Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation.
Neurobiology of aging 2012;33(8):1843.e9-17.
2012: Petroula Proitsi; Suzanne J Reeves; David C Rubinsztein; Julie Williams; Nicola Archer; Carol Brayne; Michael Gill; Gillian Hamilton; Paul Hollingworth; Conrad Iyegbe; Brian Lawlor; Simon Lovestone; Michelle K Lupton; Belinda M Martin; Michael J Owen; John F Powell
Association of serotonin and dopamine gene pathways with behavioral subphenotypes in dementia.
Neurobiology of aging 2012;33(4):791-803.
2012: Madhav Thambisetty; Muzamil Saleem; Yang An; Christos Davatzikos; Luigi Ferrucci; Andreas Güntert; Anna Kinsey; Deepthi Koka; Michael A Kraut; Simon Lovestone; Susan M Resnick
Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment.
NeuroImage 2012;59(1):212-7.
2012: Claudie Hooper; Abdul Hye; Richard Killick; Steven Lynham; Jennifer Pocock; Ricardo Sainz Fuertes; Alice Warley; Cecilia Bolondi; Simon Lovestone
Wnt3a induces exosome secretion from primary cultured rat microglia.
BMC neuroscience 2012;13():144.
2012: Ines Greco; Iwona Kłoszewska; Julie Barnes; Nicola Day; Patrizia Mecocci; Jane Reed; Joanna Riddoch-Contreras; Andrew Simmons; Hilkka Soininen; Christian Spenger; Magda Tsolaki; Bruno Vellas; Lars-Olof Wahlund; Simon Lovestone
Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation.
Journal of translational medicine 2012;10():217.
2012: Steven John Kiddle; Iwona Kloszewska; Simon Lovestone; Katie Lunnon; Michelle Katharine Lupton; Patrizia Mecocci; Stephen Newhouse; Ian Pike; Joanna Riddoch-Contreras; Andrew Simmons; Hilkka Soininen; Madhav Thambisetty; Magda Tsolaki; Bruno Vellas; Malcolm Ward; Eric Westman; Richard Dobson; Abdul Hye; Caroline Johnston
Plasma based markers of [11C] PiB-PET brain amyloid burden.
PloS one 2012;7(9):e44260.
2012: Iain Rogers; John Hardy; Fiona Kerr; Simon Lovestone; Pedro Martinez; Linda Partridge
Ageing increases vulnerability to aβ42 toxicity in Drosophila.
PloS one 2012;7(7):e40569.
2012: Matthew N Davies; Abhishek Dixit; Richard Dobson; Ronald Harris; Simon Lovestone; Katie Lunnon; Aleksandar Milosavljevic; Ruth Pidsley; Leonard C Schalkwyk; Claire Troakes; Manuela Volta; Safa Al-Sarraj; Cristian Coarfa; Jonathan Mill
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood.
Genome biology 2012;13(6):R43.
2012: Katie Lunnon; Patrizia Mecocci; Stephen Newhouse; Petroula Proitsi; Muzamil Saleem; Martina Sattlecker; Andrew Simmons; Hilkka Soininen; Magda Tsolaki; Bruno Vellas; Giovanni Coppola; Richard Dobson; Simon J Furney; Daniel Geschwind; Angela Hodges; Zina Ibrahim; Iwona Kłoszewska; Anbarasu Lourdusamy; Simon Lovestone
Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood.
Journal of Alzheimer's disease : JAD 2012;30(3):685-710.
2012: Latha Velayudhan; Malcolm Ward; Andreas Güntert; Steven Lynham; John Powell; Alvina W M To; Abdul Hye; Richard Killick; Anna Kinsey; Rufina Leung; Anbarasu Lourdusamy; Simon Lovestone
Plasma transthyretin as a candidate marker for Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2012;28(2):369-75.
2011: Rebecca Sims; A David Smith; Alexandra Stretton; Charlene Thomas; Stephen Todd; Richard Abraham; Nicholas J Bass; Carol Brayne; Kristelle S Brown; Jade Chapman; John Collinge; David Craig; Kimberley Dowzell; Sarah Dwyer; Nick C Fox; Amy Gerrish; Michael Gill; Hugh Gurling; John Hardy; Denise Harold; Paul Hollingworth; Peter A Holmans; Clive Holmes; Dobril Ivanov; Janet A Johnston; Lesley Jones; Nicola Jones; Patrick G Kehoe; Brian Lawlor; Gill Livingston; Seth Love; Simon Lovestone; Michelle K Lupton; Aoibhinn Lynch; David Mann; Bernadette McGuiness; Andrew McQuillin; Simon Mead; Kevin Morgan; Valentina Moskvina; Michael O'Donovan; Michael J Owen; Jaspreet Singh Pahwa; Peter A Passmore; John Powell; Petroula Proitsi; Martin N Rossor; David C Rubinsztein; Julie Williams
No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(7):764-71.
2011: John Hardy; Rita Guerreiro; Simon Lovestone
Clusterin as an Alzheimer biomarker.
Archives of neurology 2011;68(11):1459-60.
2011: Simon J Furney; A Hodges; S Kim; Iwona Kloszewska; Mark Lathrop; Simon Lovestone; K Lunnon; Patrizia Mecocci; I Pedroso; J Powell; P Proitsi; A J Saykin; L Shen; Andrew Simmons; Hilkka Soininen; Christian Spenger; M Tsolaki; Bruno Vellas; Lars-Olof Wahlund; M W Weiner; Gerome Breen
Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.
Molecular psychiatry 2011;16(11):1130-8.
2011: F Kerr; Simon Lovestone; M J Allen; H Augustin; C Gandy; M D W Piper; L Partridge
Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease.
Neurobiology of aging 2011;32(11):1977-89.
2011: Matthew J Kempton; Simon Lovestone; Anne Schmechtig; Simon Brunton; Bill Crum; Ulrich Ettinger; Sophia Frangou; mocan dksok serega; Floris Stylios; Tracy S A Underwood; Steven C R Williams; Andrew Simmons
A comprehensive testing protocol for MRI neuroanatomical segmentation techniques: Evaluation of a novel lateral ventricle segmentation method.
NeuroImage 2011;58(4):1051-9.
2011: Eric Westman; Iwona Kłoszewska; Simon Lovestone; Patrizia Mecocci; J-Sebastian Muehlboeck; Andrew Simmons; Hilkka Soininen; Christian Spenger; Magda Tsolaki; Bruno Vellas; Lars-Olof Wahlund; Michael W Weiner
AddNeuroMed and ADNI: similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America.
NeuroImage 2011;58(3):818-28.
2011: Catherine M L Foy; Amanda Glover; Declan G M Murphy; Ruth O'Gorman; Andrew Simmons; Eileen M Daly; Simon Lovestone
Hippocampal proton MR spectroscopy in early Alzheimer's disease and mild cognitive impairment.
Brain topography 2011;24(3-4):316-22.
2011: James Rucker; Gunter Schumann; Robert Stewart; John Turp; Stuart Newman; Martin Baggaley; Philip Brittain; Matthew Broadbent; Mike Denis; Anne Farmer; Joanna Gray; Cerisse Gunasinghe; Simon Lovestone; Peter McGuffin
OPCRIT+: an electronic system for psychiatric diagnosis and data collection in clinical and research settings.
The British journal of psychiatry : the journal of mental science 2011;199(2):151-5.
2011: Claudie Hooper; Richard Killick; David Sugden; G Cocks; Cathy Fernandes; Simon Lovestone
Transcriptomic profiles of Wnt3a and insulin in primary cultured rat cortical neurones.
Journal of neurochemistry 2011;118(4):512-20.
2011: Melissa Lamar; Catherine M L Foy; Felix Beacher; Eileen Daly; Michaela Poppe; Nicola Archer; Vee P Prasher; Kieran C Murphy; Robin G Morris; Andrew Simmons; Simon Lovestone; Declan G M Murphy
Down syndrome with and without dementia: an in vivo proton Magnetic Resonance Spectroscopy study with implications for Alzheimer's disease.
NeuroImage 2011;57(1):63-8.
2011: C Tunnard; D Whitehead; C Hurt; Lars-Olof Wahlund; Patrizia Mecocci; M Tsolaki; Bruno Vellas; Christian Spenger; I Kłoszewska; Hilkka Soininen; Simon Lovestone; Andrew Simmons
Apathy and cortical atrophy in Alzheimer's disease.
International journal of geriatric psychiatry 2011;26(7):741-8.
2011: Yawu Liu; Simon Lovestone; Patrizia Mecocci; Sebastian Muehlboeck; Teemu Paajanen; Andrew Simmons; Tomasz Sobow; Hilkka Soininen; Christian Spenger; Magda Tsolaki; Catherine Tunnard; Bruno Vellas; Lars-Olof Wahlund; Eric Westman; Yi Zhang; Alan Evans
Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups--the AddNeuroMed study.
Neurobiology of aging 2011;32(7):1198-206.
2011: Paul Hollingworth; Peter A Holmans; Clive Holmes; Nigel M Hooper; Michael Hüll; M Arfan Ikram; Dobril Ivanov; Frank Jessen; Karl-Heinz Jöckel; Lesley Jones; Nicola Jones; Palmi V Jonsson; Thorlakur Jonsson; John S K Kauwe; Patrick G Kehoe; Norman Klopp; Heike Kölsch; Johannes Kornhuber; Michael Krawczak; Jean-Charles Lambert; Mark Lathrop; Lenore J Launer; Brian Lawlor; Federico Licastro; Gill Livingston; Oscar L Lopez; Seth Love; Simon Lovestone; Michelle K Lupton; Aoibhinn Lynch; Wolfgang Maier; Michelangelo Mancuso; David Mann; Ignacio Mateo; Manuel Mayhaus; Kevin Mayo; Bernadette McGuinness; Andrew McQuillin; Simon Mead; Susanne Moebus; Kevin Morgan; John C Morris; Valentina Moskvina; Thomas W Mühleisen; Benedetta Nacmias; S Nicolhaus; Markus M Nöthen; Petra Nowotny; Michael O'Donovan; Michael J Owen; Jaspreet Singh Pahwa; V Shane Pankratz; Francesco Panza; Florence Pasquier; Peter A Passmore; Ronald C. Petersen; Paola Piccardi; Alberto Pilotto; Elisa Porcellini; John Powell; Petroula Proitsi; Alex Richards; Caterina Riehle; Matthias Riemenschneider; Martin N Rossor; David C Rubinsztein; Dan Rujescu; Eckart Rüther; Sigrid B Sando; Elio Scarpini; Stefan Schreiber; Britta Schürmann; Davide Seripa; Sudha Seshadri; Christopher E Shaw; Gabriele Siciliano; Rebecca Sims; Andrew B Singleton; Kristel Sleegers; A David Smith; Jon Snaedal; Hilkka Soininen; Vincenzo Solfrizzi; Sandro Sorbi; Hreinn Stefansson; Kari Stefansson; Stacy Steinberg; Alexandra Stretton; Charlene Thomas; Stephen Todd; Magda Tsolaki; Christophe Tzourio; Christine Van Broeckhoven; Hendrik van den Bussche; Cornelia M van Duijn; Emma R L C Vardy; Stefan Wagenpfeil; Donald Warden; H-Erich Wichmann; Caroline Widdowson; Gordon Wilcock; Jan O Aasly; Richard Abraham; Ammar Al-Chalabi; Annick Alpérovitch; Victoria Alvarez; Philippe Amouyel; Giorgio Annoni; Beatrice Arosio; Maria Barcikowska; Nicholas J Bass; Helen Beaumont; Claudine Berr; Karolien Bettens; Sigurbjörn Björnsson; Paolo Bosco; Paola Bossù; Carol Brayne; Monique Breteler; Alexis Brice; Kristelle S Brown; Maria J Bullido; Dominique Campion; Minerva M Carrasquillo; Jade Chapman; Vincent Chouraki; John Collinge; Onofre Combarros; Eliecer Coto; David Craig; Carlos Cruchaga; Jean-François Dartigues; Peter P De Deyn; Marc Delepine; Panagiotis Deloukas; Anita L DeStefano; Martin Dichgans; dennis dickson; Kimberley Dowzell; Sebastiaan Engelborghs; Jacques Epelbaum; Thomas M Feulner; Annette L Fitzpatrick; Nick C Fox; Ana Frank-Garcia; Patricia Friedrich; Lutz Frölich; Daniela Galimberti; John Gallacher; Benjamin Genier-Boley; Amy Gerrish; Ina Giegling; Michael Gill; Alison Goate; Neill R Graff-Radford; Rita Guerreiro; Hugh Gurling; Rhian Gwilliam; Harald Hampel; Marian L Hamshere; Didier Hannequin; Olivier Hanon; John Hardy; Denise Harold; Reiner Heun; Isabella Heuser; Mikko Hiltunen; Jens Wiltfang; Zbigniew K Wszolek; Steven G Younkin; Diana Zelenika; Julie Williams
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
Nature genetics 2011;43(5):429-35.
2011: Sergi G Costafreda; Ivo D Dinov; Zhuowen Tu; Yonggang Shi; Cheng-Yi Liu; Iwona Kloszewska; Patrizia Mecocci; Hilkka Soininen; Magda Tsolaki; Bruno Vellas; Lars-Olof Wahlund; Christian Spenger; Arthur W Toga; Simon Lovestone; Andrew Simmons
Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment.
NeuroImage 2011;56(1):212-9.
2011: P Proitsi; G Hamilton; M Tsolaki; M Lupton; M Daniilidou; Paul Hollingworth; N Archer; C Foy; F Stylios; B McGuinness; S Todd; B Lawlor; M Gill; Carol Brayne; David C Rubinsztein; Michael J Owen; J Williams; David Craig; P Passmore; Simon Lovestone; John F Powell
A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD).
Neurobiology of aging 2011;32(3):434-42.
2011: Eric Westman; Andrew Simmons; Yi Zhang; J-Sebastian Muehlboeck; Catherine Tunnard; Yawu Liu; Louis Collins; Alan Evans; Patrizia Mecocci; Bruno Vellas; Magda Tsolaki; Iwona Kłoszewska; Hilkka Soininen; Simon Lovestone; Christian Spenger; Lars-Olof Wahlund
Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controls.
NeuroImage 2011;54(2):1178-87.
2011: Madhav Thambisetty; Magda Tsolaki; Bruno Vellas; Lars-Olof Wahlund; Eric Westman; Yi Zhang; James Campbell; Mirsada Causevic; Abdul Hye; Richard Killick; Anna Kinsey; Iwona Kloszewska; Simon Lovestone; Patrizia Mecocci; Andrew Simmons; Hilkka Soininen; Christian Spenger
Plasma biomarkers of brain atrophy in Alzheimer's disease.
PloS one 2011;6(12):e28527.
2011: Simon J Furney; Andreas Güntert; Iwona Kloszewska; Deborah Kronenberg; Richard J Dobson; Patrizia Mecocci; Petroula Proitsi; Andrew Simmons; Hilkka Soininen; Christian Spenger; Magda Tsolaki; Bruno Vellas; Lars-Olof Wahlund; Simon Lovestone
Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease--cytokines and MRI measures together predict disease progression.
Journal of Alzheimer's disease : JAD 2011;26 Suppl 3():395-405.
2011: Eric Westman; Christian Spenger; Lars-Olof Wahlund; Allison Cooper; Catherine Foy; Simon Lovestone; Declan Murphy; Michaela Poppe; Andrew Simmons
Magnetic resonance imaging and magnetic resonance spectroscopy for detection of early Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;26 Suppl 3():307-19.
2011: Eric Westman; Yi Zhang; Lena Cavallin; Iwona Kłoszewska; Simon Lovestone; Patrizia Mecocci; J-Sebastian Muehlboeck; Andrew Simmons; Hilkka Soininen; Christian Spenger; Magda Tsolaki; Bruno Vellas; Lars-Olof Wahlund
Sensitivity and specificity of medial temporal lobe visual ratings and multivariate regional MRI classification in Alzheimer's disease.
PloS one 2011;6(7):e22506.
2011: Paul C R Hopkins; Ricardo Sáinz-Fuertes; Simon Lovestone
The impact of a novel apolipoprotein E and amyloid-β protein precursor-interacting protein on the production of amyloid-β.
Journal of Alzheimer's disease : JAD 2011;26(2):239-53.
2011: Michelle K Lupton; Petroula Proitsi; Makrina Danillidou; Magda Tsolaki; Gillian Hamilton; Richard Wroe; Megan Pritchard; Kathryn Lord; Belinda M Martin; Iwona Kloszewska; Hilkka Soininen; Patrizia Mecocci; Bruno Vellas; Denise Harold; Paul Hollingworth; Simon Lovestone; John F Powell
Deep sequencing of the Nicastrin gene in pooled DNA, the identification of genetic variants that affect risk of Alzheimer's disease.
PloS one 2011;6(2):e17298.
2011: Alvina W M To; Elena M Ribe; Tsu Tshen Chuang; Joern E Schroeder; Simon Lovestone
The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice.
PloS one 2011;6(2):e16991.
2011: Andrew Simmons; Eric Westman; Sebastian Muehlboeck; Patrizia Mecocci; Bruno Vellas; Magda Tsolaki; Iwona Kłoszewska; Lars-Olof Wahlund; Hilkka Soininen; Simon Lovestone; Alan Evans; Christian Spenger
The AddNeuroMed framework for multi-centre MRI assessment of Alzheimer's disease: experience from the first 24 months.
International journal of geriatric psychiatry 2011;26(1):75-82.
2010: Simon Lovestone
Searching for biomarkers in neurodegeneration.
Nature medicine 2010;16(12):1371-2.
2010: Mirsada Causevic; Umbreen Farooq; Simon Lovestone; Richard Killick
β-Amyloid precursor protein and tau protein levels are differently regulated in human cerebellum compared to brain regions vulnerable to Alzheimer's type neurodegeneration.
Neuroscience letters 2010;485(3):162-6.
2010: Carlos Cruchaga; John S K Kauwe; Kevin Mayo; Noah Spiegel; Sarah Bertelsen; Petra Nowotny; Aarti R Shah; Richard Abraham; Paul Hollingworth; Denise Harold; Michael J Owen; Julie Williams; Simon Lovestone; Elaine R Peskind; Ge Li; James B Leverenz; Douglas Galasko; John C Morris; Anne M Fagan; David M Holtzman; Alison Goate
SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease.
PLoS genetics 2010;6(9):.
2010: Oyinkan Sofola; Fiona Kerr; Iain Rogers; Richard Killick; Hrvoje Augustin; Carina Gandy; Marcus J Allen; John Hardy; Simon Lovestone; Linda Partridge
Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease.
PLoS genetics 2010;6(9):.
2010: Yawu Liu; Teemu Paajanen; Yi Zhang; Eric Westman; Lars-Olof Wahlund; Andrew Simmons; Catherine Tunnard; Tomasz Sobow; Patrizia Mecocci; Magda Tsolaki; Bruno Vellas; Sebastian Muehlboeck; Alan Evans; Christian Spenger; Simon Lovestone; Hilkka Soininen
Analysis of regional MRI volumes and thicknesses as predictors of conversion from mild cognitive impairment to Alzheimer's disease.
Neurobiology of aging 2010;31(8):1375-85.
2010: Felicity Callard; Simon Lovestone; Megan Pritchard
Giving dementia a voice.
Mental health today (Brighton, England) 2010;():34-5.
2010: Madhav Thambisetty; Andrew Simmons; Latha Velayudhan; Abdul Hye; James Campbell; Yi Zhang; Lars-Olof Wahlund; Eric Westman; Anna Kinsey; Andreas Güntert; Petroula Proitsi; John Powell; Mirsada Causevic; Richard Killick; Katie Lunnon; Steven Lynham; Martin Broadstock; Fahd Choudhry; David R Howlett; Robert J Williams; Sally I Sharp; Cathy Mitchelmore; Catherine Tunnard; Rufina Leung; Catherine Foy; Darragh O'Brien; Gerome Breen; Simon J Furney; Malcolm Ward; Iwona Kloszewska; Patrizia Mecocci; Hilkka Soininen; Magda Tsolaki; Bruno Vellas; Angela Hodges; Declan G M Murphy; Sue Parkins; Jill C Richardson; Susan M Resnick; Luigi Ferrucci; Dean F Wong; Yun Zhou; Sebastian Muehlboeck; Alan Evans; Paul T Francis; Christian Spenger; Simon Lovestone
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease.
Archives of general psychiatry 2010;67(7):739-48.
2010: John S K Kauwe; Sarah Bertelsen; Kevin Mayo; Carlos Cruchaga; Richard Abraham; Paul Hollingworth; D Harold; Michael J Owen; Julie Williams; Simon Lovestone; John C Morris; Alison Goate
Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(4):955-9.
2010: Felix Beacher; Eileen Daly; Andrew Simmons; V Prasher; R Morris; C Robinson; Simon Lovestone; Kieran Murphy; D G M Murphy
Brain anatomy and ageing in non-demented adults with Down's syndrome: an in vivo MRI study.
Psychological medicine 2010;40(4):611-9.
2010: Helen Nicholas; Paul Moran; Catherine Foy; Richard G Brown; Simon Lovestone; Stephanie Bryant; Harry Boothby
Are abnormal premorbid personality traits associated with Alzheimer's disease? - A case-control study.
International journal of geriatric psychiatry 2010;25(4):345-51.
2010: C S Hurt; Sube Banerjee; C Tunnard; D L Whitehead; M Tsolaki; P Mecocci; Iwona Kloszewska; Hilkka Soininen; Bruno Vellas; Simon Lovestone
Insight, cognition and quality of life in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2010;81(3):331-6.
2010: Madhav Thambisetty; Simon Lovestone
Blood-based biomarkers of Alzheimer's disease: challenging but feasible.
Biomarkers in medicine 2010;4(1):65-79.
2010: Lesley Jones; Peter A Holmans; Marian L Hamshere; Denise Harold; Valentina Moskvina; Dobril Ivanov; Andrew Pocklington; Richard Abraham; Paul Hollingworth; Rebecca Sims; Amy Gerrish; Jaspreet Singh Pahwa; Nicola Jones; Alexandra Stretton; Angharad R Morgan; Simon Lovestone; John Powell; Petroula Proitsi; Michelle K Lupton; Carol Brayne; David C Rubinsztein; Michael Gill; Brian Lawlor; Aoibhinn Lynch; Kevin Morgan; Kristelle S Brown; Peter A Passmore; David Craig; Bernadette McGuinness; Stephen Todd; Clive Holmes; David Mann; A David Smith; Seth Love; Patrick G Kehoe; Simon Mead; Nick C Fox; Martin N Rossor; John Collinge; Wolfgang Maier; Frank Jessen; Britta Schürmann; Reinhard Heun; Heike Kölsch; Hendrik van den Bussche; Isabella Heuser; Oliver Peters; Johannes Kornhuber; Jens Wiltfang; Martin Dichgans; Lutz Frölich; Harald Hampel; Michael Hüll; Dan Rujescu; Alison Goate; John S K Kauwe; Carlos Cruchaga; Petra Nowotny; John C Morris; Kevin Mayo; Gill Livingston; Nicholas J Bass; Hugh Gurling; Andrew McQuillin; Rhian Gwilliam; Panos Deloukas; Ammar Al-Chalabi; Christopher E Shaw; Andrew Singleton; Rita Guerreiro; Thomas W Mühleisen; Markus M Nöthen; Susanne Moebus; Karl-Heinz Jöckel; Norman Klopp; H-Erich Wichmann; Eckhard Rüther; Minerva M Carrasquillo; V Shane Pankratz; Steven G Younkin; John Hardy; Michael C O'Donovan; Michael J Owen; Julie Williams
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.
PloS one 2010;5(11):e13950.
2010: Teemu Paajanen; Tuomo Hänninen; Catherine Tunnard; Patrizia Mecocci; Tomasz Sobow; Magda Tsolaki; Bruno Vellas; Simon Lovestone; Hilkka Soininen
CERAD neuropsychological battery total score in multinational mild cognitive impairment and control populations: the AddNeuroMed study.
Journal of Alzheimer's disease : JAD 2010;22(4):1089-97.
2010: Madhav Thambisetty; Romina Tripaldi; Joanna Riddoch-Contreras; Abdul Hye; Yang An; James Campbell; Jitka Sojkova; Anna Kinsey; Steven Lynham; Yun Zhou; Luigi Ferrucci; Dean F Wong; Simon Lovestone; Susan M Resnick
Proteome-based plasma markers of brain amyloid-β deposition in non-demented older individuals.
Journal of Alzheimer's disease : JAD 2010;22(4):1099-109.
2010: Yawu Liu; Teemu Paajanen; Eric Westman; Yi Zhang; Lars-Olof Wahlund; Andrew Simmons; Catherine Tunnard; Tomasz Sobow; Petroula Proitsi; John Powell; Patrizia Mecocci; Magda Tsolaki; Bruno Vellas; Sebastian Muehlboeck; Alan Evans; Christian Spenger; Simon Lovestone; Hilkka Soininen
APOE ε2 allele is associated with larger regional cortical thicknesses and volumes.
Dementia and geriatric cognitive disorders 2010;30(3):229-37.
2010: Eric Westman; Lars-Olof Wahlund; Catherine Foy; Michaella Poppe; Allison Cooper; Declan Murphy; Christian Spenger; Simon Lovestone; Andrew Simmons
Combining MRI and MRS to distinguish between Alzheimer's disease and healthy controls.
Journal of Alzheimer's disease : JAD 2010;22(1):171-81.
2010: Yawu Liu; Teemu Paajanen; Eric Westman; Lars-Olof Wahlund; Andrew Simmons; Catherine Tunnard; Tomasz Sobow; Petroula Proitsi; John Powell; Patrizia Mecocci; Magda Tsolaki; Bruno Vellas; Sebastian Muehlboeck; Alan Evans; Christian Spenger; Simon Lovestone; Hilkka Soininen
Effect of APOE ε4 allele on cortical thicknesses and volumes: the AddNeuroMed study.
Journal of Alzheimer's disease : JAD 2010;21(3):947-66.
2010: Andreas Güntert; James Campbell; Muzamil Saleem; Darragh P O'Brien; Andrew J Thompson; Helen L Byers; Malcolm A Ward; Simon Lovestone
Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;21(2):585-96.
2010: Graham Cocks; Jonathan Wilde; Simon J Graham; Vicky Bousgouni; David Virley; Simon Lovestone; Jill Richardson
The thiazolidinedione pioglitazone increases cholesterol biosynthetic gene expression in primary cortical neurons by a PPARgamma-independent mechanism.
Journal of Alzheimer's disease : JAD 2010;19(2):631-46.
2010: Latha Velayudhan; Michaela Poppe; Nicola Archer; Petroula Proitsi; Richard G Brown; Simon Lovestone
Risk of developing dementia in people with diabetes and mild cognitive impairment.
The British journal of psychiatry : the journal of mental science 2010;196(1):36-40.
2010: Michelle K Lupton; Daniel Stahl; Nicola Archer; Catherine Foy; Michaela Poppe; Simon Lovestone; Paul Hollingworth; Julie Williams; Michael J Owen; Kimberley Dowzell; Richard Abraham; Rebecca Sims; Carol Brayne; David C Rubinsztein; Michael Gill; Brian A Lawlor; Aoibhinn Lynch; John F Powell
Education, occupation and retirement age effects on the age of onset of Alzheimer's disease.
International journal of geriatric psychiatry 2010;25(1):30-6.
2009: Andrew Simmons; Eric Westman; Sebastian Muehlboeck; Patrizia Mecocci; Bruno Vellas; Magda Tsolaki; Iwona Kłoszewska; Lars-Olof Wahlund; Hilkka Soininen; Simon Lovestone; Alan Evans; Christian Spenger
MRI measures of Alzheimer's disease and the AddNeuroMed study.
Annals of the New York Academy of Sciences 2009;1180():47-55.
2009: Simon Lovestone; Paul Francis; Iwona Kloszewska; Patrizia Mecocci; Andrew Simmons; Hilkka Soininen; Christian Spenger; Magda Tsolaki; Bruno Vellas; Lars-Olof Wahlund; Malcolm Ward
AddNeuroMed--the European collaboration for the discovery of novel biomarkers for Alzheimer's disease.
Annals of the New York Academy of Sciences 2009;1180():36-46.
2009: Simon Lovestone
Biomarkers in brain disease. Preface.
Annals of the New York Academy of Sciences 2009;1180():vii.
2009: Denise Harold; Richard Abraham; Paul Hollingworth; Rebecca Sims; Amy Gerrish; Marian L Hamshere; Jaspreet Singh Pahwa; Valentina Moskvina; Kimberley Dowzell; Amy Williams; Nicola Jones; Charlene Thomas; Alexandra Stretton; Angharad R Morgan; Simon Lovestone; John Powell; Petroula Proitsi; Michelle K Lupton; Carol Brayne; David C Rubinsztein; Michael Gill; Brian Lawlor; Aoibhinn Lynch; Kevin Morgan; Kristelle S Brown; Peter A Passmore; David Craig; Bernadette McGuinness; Stephen Todd; Clive Holmes; D M A Mann; A David Smith; Seth Love; Patrick G Kehoe; John Hardy; Simon Mead; Nick C Fox; Martin N Rossor; John Collinge; Wolfgang Maier; Frank Jessen; Britta Schürmann; Hendrik van den Bussche; Isabella Heuser; Johannes Kornhuber; Jens Wiltfang; Martin Dichgans; Lutz Froelich; Harald Hampel; Michael Hüll; Dan Rujescu; Alison Goate; John S K Kauwe; Carlos Cruchaga; Petra Nowotny; John C Morris; Kevin Mayo; Kristel Sleegers; Karolien Bettens; Sebastiaan Engelborghs; Peter P De Deyn; Christine Van Broeckhoven; Gillian Livingston; Nicholas J Bass; Hugh Gurling; Andrew McQuillin; Rhian Gwilliam; Panagiotis Deloukas; Ammar Al-Chalabi; Christopher Shaw; Magda Tsolaki; Andrew Singleton; Rita Guerreiro; Thomas W Mühleisen; Markus M Nöthen; Susanne Moebus; Karl-Heinz Jöckel; Norman Klopp; H-Erich Wichmann; Minerva M Carrasquillo; V Shane Pankratz; Steven G Younkin; Peter A Holmans; Michael O'Donovan; Michael J Owen; Julie Williams
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Nature genetics 2009;41(10):1088-93.
2009: R Sims; Paul Hollingworth; Valentina Moskvina; K Dowzell; Michael C O'Donovan; John Powell; Simon Lovestone; Carol Brayne; David C Rubinsztein; Michael J Owen; Julie Williams; Richard Abraham
Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease.
Neuroscience letters 2009;461(1):54-9.
2009: Richard Killick; Georgie Scales; Karelle Leroy; Mirsada Causevic; Claudie Hooper; Elaine E Irvine; Agharul I Choudhury; Laura Drinkwater; Fiona Kerr; Hind Al-Qassab; John Stephenson; Zehra Yilmaz; peter giese; Jean-Pierre Brion; Dominic J Withers; Simon Lovestone
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice.
Biochemical and biophysical research communications 2009;386(1):257-62.
2009: Latha Velayudhan; Simon Lovestone
Smell identification test as a treatment response marker in patients with Alzheimer disease receiving donepezil.
Journal of clinical psychopharmacology 2009;29(4):387-90.
2009: Simon Lovestone; Madhav Thambisetty
Biomarkers for Alzheimer's disease trials--biomarkers for what? A discussion paper.
The journal of nutrition, health & aging 2009;13(4):334-6.
2009: Nicola Greenberg; Antonio Grassano; Madhav Thambisetty; Simon Lovestone; Cristina Legido-Quigley
A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease.
Electrophoresis 2009;30(7):1235-9.
2009: Nicola Archer; Richard Brown; S Reeves; Helen Nicholas; Harry Boothby; Simon Lovestone
Midlife Neuroticism and the age of onset of Alzheimer's disease.
Psychological medicine 2009;39(4):665-73.
2009: Felix Beacher; Eileen Daly; Andrew Simmons; V Prasher; R Morris; C Robinson; Simon Lovestone; Kieran Murphy; Declan G M Murphy
Alzheimer's disease and Down's syndrome: an in vivo MRI study.
Psychological medicine 2009;39(4):675-84.
2009: A R Morgan; Paul Hollingworth; Richard Abraham; Simon Lovestone; Carol Brayne; David C Rubinsztein; A Lynch; Brian A Lawlor; Michael Gill; Michael C O'Donovan; Michael J Owen; Julie Williams
Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(1):61-4.
2009: Robert Stewart; Mishael Soremekun; Gayan Perera; Matthew Broadbent; Felicity Callard; Mike Denis; Matthew Hotopf; Graham Thornicroft; Simon Lovestone
The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) case register: development and descriptive data.
BMC psychiatry 2009;9():51.
2008: Bengt Winblad; Giovanni B Frisoni; L Frolich; P Johannsen; G Johansson; Pat Kehoe; Simon Lovestone; M Olde-Rikkert; E Reynish; P J Visser; Bruno Vellas
Editorial: EADC (European Alzheimer Disease Consortium) recommendations for future Alzheimer disease research in Europe.
The journal of nutrition, health & aging 2008;12(10):683-4.
2008: Madhav Thambisetty; Abdul Hye; Catherine Foy; Eileen Daly; Amanda Glover; Allison Cooper; Andrew Simmons; Declan Murphy; Simon Lovestone
Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease.
Journal of neurology 2008;255(11):1712-20.
2008: John B J Kwok; Clement T Loy; Gillian Hamilton; Edmond Lau; Marianne Hallupp; Julie Williams; Michael J Owen; G Anthony Broe; Nelson Tang; Linda Lam; John F Powell; Simon Lovestone; Peter R Schofield
Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease.
Annals of neurology 2008;64(4):446-54.
2008: A R Morgan; Gillian Hamilton; Darko Turic; Luke Jehu; Denise Harold; Richard Abraham; Paul Hollingworth; Valentina Moskvina; Carol Brayne; David C Rubinsztein; A Lynch; Brian A Lawlor; Michael Gill; Michael O'Donovan; John Powell; Simon Lovestone; Julie Williams; Michael J Owen
Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(6):727-31.
2008: Alastair Macdonald; Kate Briggs; Michaela Poppe; Andrea Higgins; Latha Velayudhan; Simon Lovestone
A feasibility and tolerability study of lithium in Alzheimer's disease.
International journal of geriatric psychiatry 2008;23(7):704-11.
2008: Raya Al-Shawi; Angela Hafner; Jessica Olsen; Jessica Olson; Soyon Chun; Saba Raza; Christopher Thrasivoulou; Simon Lovestone; Richard Killick; Paul Simons; Timothy Cowen
Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system.
The European journal of neuroscience 2008;27(8):2103-14.
2008: Claudie Hooper; Richard Killick; Simon Lovestone
The GSK3 hypothesis of Alzheimer's disease.
Journal of neurochemistry 2008;104(6):1433-9.
2008: Yonghong Li; Andrew Grupe; Charles Rowland; Peter Holmans; Ricardo Segurado; Richard Abraham; Lesley Jones; Joseph J Catanese; David Ross; Kevin Mayo; Maribel Martinez; Paul Hollingworth; Alison Goate; Nigel J Cairns; Brad A Racette; Joel S Perlmutter; Michael C O'Donovan; John C Morris; Carol Brayne; David C Rubinsztein; Simon Lovestone; Leon J Thal; Michael J Owen; Julie Williams
Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.
Human molecular genetics 2008;17(5):759-67.
2008: Yonghong Li; Charles Rowland; Joseph J Catanese; John C Morris; Simon Lovestone; Michael C O'Donovan; Alison Goate; Michael J Owen; Julie Williams; Andrew Grupe
SORL1 variants and risk of late-onset Alzheimer's disease.
Neurobiology of disease 2008;29(2):293-6.
2008: Hao Li; Sally Wetten; Li Li; Pamela L St Jean; Ruchi Upmanyu; Linda Surh; David Hosford; Michael R Barnes; James David Briley; Michael Borrie; Natalie Coletta; Richard Delisle; Daniella Dhalla; Margaret G Ehm; Howard H Feldman; Luis Fornazzari; S Gauthier; Neil Goodgame; Danilo Guzman; Sandra Hammond; Paul Hollingworth; Ging-Yuek Hsiung; Joan Johnson; Devon D Kelly; Ron Keren; Andrew Kertesz; Karen S King; Simon Lovestone; Inge Loy-English; Paul Matthews; Michael J Owen; Mary Plumpton; William Pryse-Phillips; Rab Prinjha; Jill C Richardson; Ann M Saunders; Andrew J Slater; Peter St George-Hyslop; Sandra W Stinnett; Jina Swartz; Rachel L Taylor; John Wherrett; Julie Williams; David P Yarnall; Rachel A Gibson; Michael C Irizarry; Lefkos T Middleton; Allen D Roses
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Archives of neurology 2008;65(1):45-53.
2008: Petroula Proitsi; Tao Li; Gillian Hamilton; Marta Di Forti; David Collier; Richard Killick; Ronald Chen; Pak Sham; Robin Murray; John Powell; Simon Lovestone
Positional pathway screen of wnt signaling genes in schizophrenia: association with DKK4.
Biological psychiatry 2008;63(1):13-6.
2007: Marian Hamshere; Peter Holmans; Dimitrios Avramopoulos; Susan S Bassett; Deborah Blacker; Lars Bertram; Howard Wiener; Nan Rochberg; Rudolph E Tanzi; Amanda Myers; Fabienne Wavrant-De Vrièze; Rodney Go; Daniele Fallin; Simon Lovestone; John Hardy; Alison Goate; Michael O'Donovan; Julie Williams; Michael J Owen
Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease.
Human molecular genetics 2007;16(22):2703-12.
2007: Catherine M L Foy; Helen Nicholas; Paul Hollingworth; Harry Boothby; Julie Willams; Richard Brown; Safa Al-Sarraj; Simon Lovestone
Diagnosing Alzheimer's disease--non-clinicians and computerised algorithms together are as accurate as the best clinical practice.
International journal of geriatric psychiatry 2007;22(11):1154-63.
2007: Paul Hollingworth; Marian Hamshere; Peter Holmans; Michael C O'Donovan; Rebecca Sims; John Powell; Simon Lovestone; Amanda Myers; FW DeVrieze; John Hardy; Alison Goate; Michael J Owen; Julie Williams
Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(7):841-8.
2007: A R Morgan; Darko Turic; Luke Jehu; Gillian Hamilton; Paul Hollingworth; Valentina Moskvina; Lesley Jones; Simon Lovestone; Carol Brayne; David C Rubinsztein; Brian A Lawlor; Michael Gill; Michael C O'Donovan; Michael J Owen; Julie Williams
Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(6):762-70.
2007: Simon Lovestone; Paul T Francis; K Strandgaard
Biomarkers for disease modification trials--the innovative medicines initiative and AddNeuroMed.
The journal of nutrition, health & aging 2007;11(4):359-61.
2007: Gillian Hamilton; Petra Proitsi; Luke Jehu; Angharad Morgan; Julie Williams; Michael C O'Donovan; Michael J Owen; John F Powell; Simon Lovestone
Candidate gene association study of insulin signaling genes and Alzheimer's disease: evidence for SOS2, PCK1, and PPARgamma as susceptibility loci.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(4):508-16.
2007: Denise Harold; Luke Jehu; Darko Turic; Paul Hollingworth; Pamela Moore; P Summerhayes; Valentina Moskvina; Catherine Foy; Nicola Archer; B A Hamilton; Simon Lovestone; John Powell; Carol Brayne; David C Rubinsztein; Lesley Jones; Michael C O'Donovan; Michael J Owen; Julie Williams
Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(4):448-52.
2007: Claudie Hooper; Eirini Meimaridou; Mahvash Tavassoli; Gerry Melino; Simon Lovestone; Richard Killick
p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells.
Neuroscience letters 2007;418(1):34-7.
2007: Andrew Grupe; Richard Abraham; Yonghong Li; Charles Rowland; Paul Hollingworth; Angharad Morgan; Luke Jehu; Ricardo Segurado; David Stone; Eric Schadt; Maha Karnoub; Petra Nowotny; Kristina Tacey; Joseph J Catanese; John J Sninsky; Carol Brayne; David C Rubinsztein; Michael Gill; Brian A Lawlor; Simon Lovestone; Peter Holmans; Michael O'Donovan; John C Morris; Leon J Thal; Alison Goate; Michael J Owen; Julie Williams
Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants.
Human molecular genetics 2007;16(8):865-73.
2007: Simon Lovestone; Andreas Güntert; Abdul Hye; Steven Lynham; Madhav Thambisetty; Malcolm Ward
Proteomics of Alzheimer's disease: understanding mechanisms and seeking biomarkers.
Expert review of proteomics 2007;4(2):227-38.
2007: Simon Lovestone; Richard Killick; Marta Di Forti; Robin Murray
Schizophrenia as a GSK-3 dysregulation disorder.
Trends in neurosciences 2007;30(4):142-9.
2007: Claudie Hooper; J Paul Chapple; Simon Lovestone; Richard Killick
The Notch-1 intracellular domain is found in sub-nuclear bodies in SH-SY5Y neuroblastomas and in primary cortical neurons.
Neuroscience letters 2007;415(2):135-9.
2007: Nicola Archer; Richard Brown; Suzanne J Reeves; Harry Boothby; Helen Nicholas; Catherine Foy; Julie Williams; Simon Lovestone
Premorbid personality and behavioral and psychological symptoms in probable Alzheimer disease.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2007;15(3):202-13.
2007: Naushaba Nayeem; Fiona Kerr; Heike Naumann; Jackie Linehan; Simon Lovestone; Sebastian Brandner
Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella.
Molecular and cellular neurosciences 2007;34(3):400-8.
2007: John Ellul; Nicola Archer; C M L Foy; Michaela Poppe; Harry Boothby; Helen Nicholas; Richard Brown; Simon Lovestone
The effects of commonly prescribed drugs in patients with Alzheimer's disease on the rate of deterioration.
Journal of neurology, neurosurgery, and psychiatry 2007;78(3):233-9.
2007: Annat F Ikin; Mirsada Causevic; Steve Pedrini; Lyndsey S Benson; Joseph Buxbaum; Toshiharu Suzuki; Simon Lovestone; Shigeki Higashiyama; Tomas Mustelin; Robert D Burgoyne; Sam Gandy
Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding.
Molecular neurodegeneration 2007;2():23.
2007: Gillian Hamilton; Petra Proitsi; Julie Williams; Michael O'Donovan; Michael J Owen; John Powell; Simon Lovestone
Complement factor H Y402H polymorphism is not associated with late-onset Alzheimer's disease.
Neuromolecular medicine 2007;9(4):331-4.
2007: Claudie Hooper; Vladimir Markevich; Florian Plattner; Richard Killick; Emma Schofield; Tobias Engel; Felix Hernandez; Brian H Anderton; Kobi Rosenblum; T V P Bliss; Sam F Cooke; Jesús Avila; José J Lucas; peter giese; John Stephenson; Simon Lovestone
Glycogen synthase kinase-3 inhibition is integral to long-term potentiation.
The European journal of neuroscience 2007;25(1):81-6.
2006: Ayodeji A Asuni; Claudie Hooper; C Hugh Reynolds; Simon Lovestone; Brian H Anderton; Richard Killick
GSK3alpha exhibits beta-catenin and tau directed kinase activities that are modulated by Wnt.
The European journal of neuroscience 2006;24(12):3387-92.
2006: Claudie Hooper; Mahvash Tavassoli; J Paul Chapple; Dafe Uwanogho; Richard Goodyear; Gerry Melino; Simon Lovestone; Richard Killick
TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones.
Journal of neurochemistry 2006;99(3):989-99.
2006: Abdul Hye; S Lynham; Madhav Thambisetty; Mirsada Causevic; J Campbell; Helen L Byers; Claudie Hooper; F Rijsdijk; Sarah J Tabrizi; Steve Banner; Christopher Shaw; Catherine Foy; Michaela Poppe; Nicola Archer; Gillian Hamilton; John Powell; Richard Brown; P Sham; Malcolm Ward; Simon Lovestone
Proteome-based plasma biomarkers for Alzheimer's disease.
Brain : a journal of neurology 2006;129(Pt 11):3042-50.
2006: Paul Hollingworth; Marian Hamshere; Valentina Moskvina; Kimberley Dowzell; Pamela J Moore; Catherine Foy; Nicola Archer; Aoibhinn Lynch; Simon Lovestone; Carol Brayne; David C Rubinsztein; Brian A Lawlor; Mike Gill; Michael J Owen; Julie Williams
Four components describe behavioral symptoms in 1,120 individuals with late-onset Alzheimer's disease.
Journal of the American Geriatrics Society 2006;54(9):1348-54.
2006: Deborah Blacker; Simon Lovestone
Genetics and dementia nosology.
Journal of geriatric psychiatry and neurology 2006;19(3):186-91.
2006: Yonghong Li; Andrew Grupe; Charles Rowland; Petra Nowotny; John S K Kauwe; Scott Smemo; Anthony L Hinrichs; Kristina Tacey; Timothy A Toombs; Shirley Kwok; Joseph J Catanese; Thomas J White; Taylor J Maxwell; Paul Hollingworth; Richard Abraham; David C Rubinsztein; Carol Brayne; Fabienne Wavrant-De Vrièze; John Hardy; Michael O'Donovan; Simon Lovestone; John C Morris; Leon J Thal; Michael J Owen; Julie Williams; Alison Goate
DAPK1 variants are associated with Alzheimer's disease and allele-specific expression.
Human molecular genetics 2006;15(17):2560-8.
2006: Claudie Hooper; Richard Killick; Mahvash Tavassoli; Gerry Melino; Simon Lovestone
TAp73alpha induces tau phosphorylation in HEK293a cells via a transcription-dependent mechanism.
Neuroscience letters 2006;401(1-2):30-4.
2006: Gillian Hamilton; Farzana Samedi; Jo Knight; Nicola Archer; Catherine Foy; Sarah Walter; Darko Turic; Luke Jehu; Pamela Moore; Paul Hollingworth; Michael C O'Donovan; Julie Williams; Michael J Owen; Simon Lovestone; John F Powell
Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease.
Neuroscience letters 2006;401(1-2):77-80.
2006: Fiona Kerr; Annika Rickle; Naushaba Nayeem; Sebastian Brandner; Richard Frank Cowburn; Simon Lovestone
PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3.
FEBS letters 2006;580(13):3121-8.
2006: Nicola Archer; Richard Brown; Harry Boothby; Catherine Foy; Helen Nicholas; Simon Lovestone
The NEO-FFI is a reliable measure of premorbid personality in patients with probable Alzheimer's disease.
International journal of geriatric psychiatry 2006;21(5):477-84.
2006: Simon Lovestone
Biomarkers in Alzheimer's disease.
The journal of nutrition, health & aging 2006;10(2):118-22.
2006: F Chee; Amritpal Mudher; Tracey A Newman; Matthew F Cuttle; Simon Lovestone; David Shepherd
Overexpression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions.
Biochemical Society transactions 2006;34(Pt 1):88-90.
2006: Andrew Grupe; Yonghong Li; Charles Rowland; Petra Nowotny; Anthony L Hinrichs; Scott Smemo; John S K Kauwe; Taylor J Maxwell; Sara Cherny; Lisa Doil; Kristina Tacey; Ryan van Luchene; Amanda Myers; Fabienne Wavrant-De Vrièze; Mona Kaleem; Paul Hollingworth; Luke Jehu; Catherine Foy; Nicola Archer; Gillian Hamilton; Peter Holmans; Chris M Morris; Joseph Catanese; John Sninsky; Thomas J White; John Powell; John Hardy; Michael O'Donovan; Simon Lovestone; Lesley Jones; John C Morris; Leon J Thal; Michael J Owen; Julie Williams; Alison Goate
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
American journal of human genetics 2006;78(1):78-88.
2006: Scott Smemo; Petra Nowotny; Anthony L Hinrichs; John S K Kauwe; Sara Cherny; Katherine Erickson; Amanda Myers; Mona Kaleem; Lauren Marlowe; Alison M Gibson; Paul Hollingworth; Michael C O'Donovan; Christopher M Morris; Peter Holmans; Simon Lovestone; John C Morris; Leon J Thal; Yonghong Li; Andrew Grupe; John Hardy; Michael J Owen; Julie Williams; Alison Goate
Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease.
Annals of neurology 2006;59(1):21-6.
2005: Felix Beacher; Andrew Simmons; Eileen Daly; Verinder Prasher; Claire Adams; Maria Luisa Margallo-Lana; Robin Morris; Simon Lovestone; Kieran Murphy; Declan G M Murphy
Hippocampal myo-inositol and cognitive ability in adults with Down syndrome: an in vivo proton magnetic resonance spectroscopy study.
Archives of general psychiatry 2005;62(12):1360-5.
2005: Francis C Chee; Amritpal Mudher; Matthew F Cuttle; Tracey A Newman; Daniel MacKay; Simon Lovestone; David Shepherd
Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions.
Neurobiology of disease 2005;20(3):918-28.
2005: Y Li; Charles Rowland; Kristina Tacey; Joseph J Catanese; John J Sninsky; John Hardy; J Powell; Simon Lovestone; John C Morris; Leon J Thal; Alison Goate; Michael J Owen; Julie Williams; Andrew Grupe
The BDNF Val66Met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples.
Molecular psychiatry 2005;10(9):809-10.
2005: Petra Nowotny; Anthony L Hinrichs; Scott Smemo; John S K Kauwe; Taylor Maxwell; Peter Holmans; Marian Hamshere; Darko Turic; Luke Jehu; Paul Hollingworth; Pamela Moore; Leslie Bryden; Amanda Myers; Lisa M Doil; Kristina M Tacey; Alison M Gibson; Ian G McKeith; Robert H Perry; Christopher M Morris; Leon J Thal; John C Morris; Michael C O'Donovan; Simon Lovestone; Andrew Grupe; John Hardy; Michael J Owen; Julie Williams; Alison Goate
Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;136B(1):62-8.
2005: Faiza Siyad; Jodianne Griffiths; Faira Janjua; Elizabeth Jackson; Ian Rodrigues; Fiona Kerr; Daniel Mackay; Simon Lovestone
School students as Drosophila experimenters.
PLoS biology 2005;3(7):e246.
2005: Peter Holmans; Marian Hamshere; Paul Hollingworth; Frances Rice; Nigel Tunstall; Sue Jones; Pamela Moore; Fabienne Wavrant DeVrieze; Amanda Myers; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Michael O'Donovan; Lesley Jones; John Hardy; Alison Goate; Simon Lovestone; Michael J Owen; Julie Williams
Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;135B(1):24-32.
2005: C Holmes; Clive G Ballard; D Lehmann; A David Smith; H Beaumont; Ian N M Day; M Nadeem Khan; Simon Lovestone; Michelle C McCulley; C M Morris; David G Munoz; K O'Brien; C Russ; Teodoro del Ser; Donald R Warden
Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation.
Journal of neurology, neurosurgery, and psychiatry 2005;76(5):640-3.
2005: Yonghong Li; Paul Hollingworth; Pamela Moore; Catherine Foy; Nicola Archer; John Powell; Petra Nowotny; Peter Holmans; Michael O'Donovan; Kristina Tacey; Lisa Doil; Ryan van Luchene; Veronica Garcia; Charles Rowland; Kit Lau; Joseph Cantanese; John J Sninsky; John Hardy; Leon J Thal; John C Morris; Alison Goate; Simon Lovestone; Michael J Owen; Julie Williams; Andrew Grupe
Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease.
Human mutation 2005;25(3):270-7.
2005: Ian J Deary; Gillian Hamilton; Caroline Hayward; LAWRENCE JEFFREY WHALLEY; John Powell; John M Starr; Simon Lovestone
Nicastrin gene polymorphisms, cognitive ability level and cognitive ageing.
Neuroscience letters 2005;373(2):110-4.
2005: Lynnette J Cook; Luk W Ho; Lin Wang; Edith Terrenoire; Carol Brayne; John Grimley Evans; John H Xuereb; Nigel J Cairns; Darko Turic; Paul Hollingworth; Pamela J Moore; Luke Jehu; Nicola Archer; Sarah Walter; Catherine Foy; Amanda Edmondson; John Powell; Simon Lovestone; Julie Williams; David C Rubinsztein
Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;132B(1):5-8.
2005: Abdul Hye; Fiona Kerr; Nicola Archer; Catherine Foy; Michaela Poppe; Richard Brown; Gillian Hamilton; John Powell; Brian H Anderton; Simon Lovestone
Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease.
Neuroscience letters 2005;373(1):1-4.
2004: Yonghong Li; Petra Nowotny; Peter Holmans; Scott Smemo; John S K Kauwe; Anthony L Hinrichs; Kristina Tacey; Lisa Doil; Ryan van Luchene; Veronica Garcia; Charles Rowland; Steve Schrodi; Diane Leong; Goran Gogic; Joanne Chan; Anibal Cravchik; David Ross; Kit Lau; Shirley Kwok; Sheng-Yung Chang; Joe Catanese; John Sninsky; Thomas J White; John Hardy; John Powell; Simon Lovestone; John C Morris; Leon J Thal; Michael J Owen; Julie Williams; Alison Goate; Andrew Grupe
Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(44):15688-93.
2004: Yonghong Li; Kristina Tacey; Lisa Doil; Ryan van Luchene; Veronica Garcia; Charles Rowland; Steven J Schrodi; Diane Leong; Kit Lau; Joseph J Catanese; John J Sninsky; Petra Nowotny; Peter Holmans; John Hardy; John Powell; Simon Lovestone; Leon J Thal; Michael J Owen; Julie Williams; Alison Goate; Andrew Grupe
Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study.
Neuroscience letters 2004;366(3):268-71.
2004: Jorge Cervilla; Martin Prince; Suzanne Joels; Simon Lovestone; Anthony Mann
Premorbid cognitive testing predicts the onset of dementia and Alzheimer's disease better than and independently of APOE genotype.
Journal of neurology, neurosurgery, and psychiatry 2004;75(8):1100-6.
2004: Maddalena Bruscoli; Simon Lovestone
Is MCI really just early dementia? A systematic review of conversion studies.
International psychogeriatrics / IPA 2004;16(2):129-40.
2004: Amritpal Mudher; David Shepherd; Tracey A Newman; P Mildren; J P Jukes; A Squire; A Mears; J A Drummond; S Berg; D MacKay; Ayodeji A Asuni; R Bhat; Simon Lovestone
GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila.
Molecular psychiatry 2004;9(5):522-30.
2004: Carmine M Pariante; Sarah A Thomas; Simon Lovestone; Andrew Makoff; Robert W Kerwin
Do antidepressants regulate how cortisol affects the brain?
Psychoneuroendocrinology 2004;29(4):423-47.
2004: Lynnette J Cook; Luk W Ho; Alison E Taylor; Carol Brayne; John Grimley Evans; John H Xuereb; Nigel J Cairns; Antonia Pritchard; Helen Lemmon; D M A Mann; David St Clair; Darko Turic; Paul Hollingworth; Pamela J Moore; Luke Jehu; Nicola Archer; Sarah Walter; Catherine Foy; Amanda Edmondson; John Powell; Simon Lovestone; Michael J Owen; Julie Williams; Corinne Lendon; David C Rubinsztein
Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease.
Neuroscience letters 2004;358(2):142-6.
2004: Jorge Cervilla; Martin Prince; Suzanne Joels; Carsten Russ; Simon Lovestone
Genes related to vascular disease (APOE, VLDL-R, DCP-1) and other vascular factors in late-life depression.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2004;12(2):202-10.
2004: Victoria Busby; Steven Goossens; Petra Nowotny; Gillian Hamilton; Scott Smemo; Denise Harold; Dragana Turic; Luke Jehu; Amanda Myers; Meredith Womick; Daniel Woo; Danielle Compton; Lisa M Doil; Kristina M Tacey; Kit F Lau; Safa Al-Saraj; Richard Killick; Stuart Pickering-Brown; Pamela Moore; Paul Hollingworth; Nicola Archer; Catherine Foy; Sarah Walter; Corrine Lendon; Takeshi Iwatsubo; John C Morris; Joanne Norton; D M A Mann; Barbara Janssens; John Hardy; Michael O'Donovan; Lesley Jones; Julie Williams; Peter Holmans; Michael J Owen; Andrew Grupe; John Powell; Jolanda van Hengel; Alison Goate; Frans Van Roy; Simon Lovestone
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.
Neuromolecular medicine 2004;5(2):133-46.
2004: Amanda Myers; Helen Marshall; Peter Holmans; Danielle Compton; Richard Crook; adrian mander; Petra Nowotny; Scott Smemo; Melanie Dunstan; Luke Jehu; Jen C Wang; Marian Hamshere; John C Morris; Joanne Norton; Sumi Chakraventy; Nigel Tunstall; Simon Lovestone; Ronald C. Petersen; Michael O'Donovan; Lesley Jones; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;124B(1):29-37.
2003: Karelle Leroy; Allal Boutajangout; J Richardson; Jean-Noël Octave; Simon Lovestone; Brian H Anderton; Jean-Pierre Brion
Mutant presenilin 1 proteins induce cell death and reduce tau-dependent processes outgrowth.
Neuroscience letters 2003;353(3):226-30.
2003: Carmine M Pariante; Abdul Hye; Ritchie Williamson; Andrew Makoff; Simon Lovestone; Robert W Kerwin
The antidepressant clomipramine regulates cortisol intracellular concentrations and glucocorticoid receptor expression in fibroblasts and rat primary neurones.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(9):1553-61.
2003: Denise Harold; Tim Peirce; Valentina Moskvina; Amanda Myers; Susan Jones; Paul Hollingworth; Pamela Moore; Simon Lovestone; John Powell; Catherine Foy; Nicola Archer; Sarah Walter; Amanda Edmonson; Stephen McIlroy; David Craig; Peter Passmore; Alison Goate; John Hardy; Michael O'Donovan; Julie Williams; Malcolm Liddell; Michael J Owen; Lesley Jones
Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease.
Human genetics 2003;113(3):258-67.
2003: S Fleminger; DL Oliver; Simon Lovestone; S Rabe-Hesketh; A Giora
Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication.
Journal of neurology, neurosurgery, and psychiatry 2003;74(7):857-62.
2003: Clive Holmes; Maria J Arranz; David Collier; John Powell; Simon Lovestone
Depression in Alzheimer's disease: the effect of serotonin receptor gene variation.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;119B(1):40-3.
2003: M C Ljungberg; Ayodeji A Asuni; J Pearce; Rejith Dayanandan; W März; M M Hoffmann; P Bertrand; G Siest; H T R Rupniak; Brian H Anderton; M Huettinger; Simon Lovestone
Apolipoprotein E (apoE) uptake and distribution in mammalian cell lines is dependent upon source of apoE and can be monitored in living cells.
Neuroscience letters 2003;341(1):69-73.
2003: Clive Holmes; Simon Lovestone
Long-term cognitive and functional decline in late onset Alzheimer's disease: therapeutic implications.
Age and ageing 2003;32(2):200-4.
2003: Rejith Dayanandan; Rachel Butler; Phillip R Gordon-Weeks; Andrew Matus; Stefanie Kaech; Simon Lovestone; Brian H Anderton; Jean-Marc Gallo
Dynamic properties of APC-decorated microtubules in living cells.
Cell motility and the cytoskeleton 2003;54(3):237-47.
2002: Karen Ritchie; Simon Lovestone
The dementias.
Lancet 2002;360(9347):1759-66.
2002: Amanda Thompsell; Simon Lovestone
Out of sight out of mind? Support and information given to distant and near relatives of those with dementia.
International journal of geriatric psychiatry 2002;17(9):804-7.
2002: D Liolitsa; J Powell; Simon Lovestone
Genetic variability in the insulin signalling pathway may contribute to the risk of late onset Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2002;73(3):261-6.
2002: Simon Lovestone; John Hardy
Psychotic genes or forgetful ones?
Neurology 2002;59(1):11-2.
2002: Simon Lovestone
Can we afford to develop treatments for dementia?
Journal of neurology, neurosurgery, and psychiatry 2002;72(6):685.
2002: M Cecilia Ljungberg; Rejith Dayanandan; Ayodeji A Asuni; Tom H Rupniak; Brian H Anderton; Simon Lovestone
Truncated apoE forms tangle-like structures in a neuronal cell line.
Neuroreport 2002;13(6):867-70.
2002: Simon Lovestone; Michael Philpot; James Connell; Peter Lantos; John Powell; Carsten Russ; Brian H Anderton
Genetics, molecular biology, neuropathology and phenotype of frontal lobe dementia: a case history.
The British journal of psychiatry : the journal of mental science 2002;180():455-60.
2002: Amanda Myers; Fabienne Wavrant De-Vrieze; Peter Holmans; Marian Hamshere; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Heather Knowles; John C Morris; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Frances Rice; Peter Giles; Nigel Tunstall; Lesley Jones; Simon Lovestone; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Full genome screen for Alzheimer disease: stage II analysis.
American journal of medical genetics 2002;114(2):235-44.
2002: Clive Holmes; Simon Lovestone
The clinical phenotype of familial and sporadic late onset Alzheimer's disease.
International journal of geriatric psychiatry 2002;17(2):146-9.
2002: Simon Lovestone; Declan McLoughlin
Protein aggregates and dementia: is there a common toxicity?
Journal of neurology, neurosurgery, and psychiatry 2002;72(2):152-61.
2002: Carsten Russ; Simon Lovestone; John F Powell
Identification of genomic organisation, sequence variants and analysis of the role of the human dishevelled 1 gene in late onset Alzheimer's disease.
Molecular psychiatry 2002;7(1):104-9.
2002: Amritpal Mudher; Simon Lovestone
Alzheimer's disease-do tauists and baptists finally shake hands?
Trends in neurosciences 2002;25(1):22-6.
2001: Richard Killick; CC Pollard; Ayodeji A Asuni; Amritpal Mudher; Jill C Richardson; H T R Rupniak; Paul Sheppard; Ian Varndell; Jean-Pierre Brion; Allan Levey; O A Levy; M Vestling; Richard Frank Cowburn; Simon Lovestone; Brian H Anderton
Presenilin 1 independently regulates beta-catenin stability and transcriptional activity.
The Journal of biological chemistry 2001;276(51):48554-61.
2001: Richard Abraham; Amanda Myers; Fabienne Wavrant DeVrieze; Marian Hamshere; Hollie V Thomas; Helen Marshall; Danielle Compton; Gillian Spurlock; Darko Turic; Bastiaan Hoogendoorn; Jennifer M Kwon; Ronald C. Petersen; Eric G Tangalos; J Norton; John C Morris; Ross Bullock; D Liolitsa; Simon Lovestone; John Hardy; Alison Goate; Michael O'Donovan; Julie Williams; Michael J Owen; Lesley Jones
Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.
Human genetics 2001;109(6):646-52.
2001: Simon Lovestone; D Murray
Acetylcholinesterase treatment--modelling potential demand and auditing practice.
International journal of geriatric psychiatry 2001;16(12):1136-42.
2001: C Holmes; H Smith; R Ganderton; Maria J Arranz; David Collier; J Powell; Simon Lovestone
Psychosis and aggression in Alzheimer's disease: the effect of dopamine receptor gene variation.
Journal of neurology, neurosurgery, and psychiatry 2001;71(6):777-9.
2001: Carsten Russ; John F Powell; J Zhao; Matt Baker; Michael Hutton; F Crawford; Michael Mullan; Gerwin Roks; Marc Cruts; Simon Lovestone
The microtubule associated protein Tau gene and Alzheimer's disease--an association study and meta-analysis.
Neuroscience letters 2001;314(1-2):92-6.
2001: Carmine M Pariante; Andrew Makoff; Simon Lovestone; S Feroli; A Heyden; Andrew H Miller; Robert W Kerwin
Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters.
British journal of pharmacology 2001;134(6):1335-43.
2001: Amritpal Mudher; S Chapman; J Richardson; Ayodeji A Asuni; Graham Gibb; CC Pollard; Richard Killick; T Iqbal; L Raymond; Ian Varndell; Paul Sheppard; Andrew Makoff; E Gower; Peter E Soden; P Lewis; Michael Murphy; todd golde; H T R Rupniak; Brian H Anderton; Simon Lovestone
Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(14):4987-95.
2001: Robert Stewart; Carsten Russ; M Richards; C Brayne; Simon Lovestone; A Mann
Apolipoprotein E genotype, vascular risk and early cognitive impairment in an African Caribbean population.
Dementia and geriatric cognitive disorders 2001;12(4):251-6.
2001: D Liolitsa; John F Powell; Martin Prince; Simon Lovestone
Association study of the 5-HT(2A) receptor gene polymorphism, T102C and essential hypertension.
Journal of human hypertension 2001;15(5):335-9.
2001: Carsten Russ; Simon Lovestone; John F Powell
Identification of sequence variants and analysis of the role of the glycogen synthase kinase 3 beta gene and promoter in late onset Alzheimer's disease.
Molecular psychiatry 2001;6(3):320-4.
2001: Clare Louise Beasley; David Cotter; N Khan; CC Pollard; Paul Sheppard; Ian Varndell; Simon Lovestone; Brian H Anderton; Ian Everall
Glycogen synthase kinase-3beta immunoreactivity is reduced in the prefrontal cortex in schizophrenia.
Neuroscience letters 2001;302(2-3):117-20.
2001: Robert Stewart; Carsten Russ; M Richards; C Brayne; Simon Lovestone; A Mann
Depression, APOE genotype and subjective memory impairment: a cross-sectional study in an African-Caribbean population.
Psychological medicine 2001;31(3):431-40.
2001: J W Connell; Graham Gibb; JC Betts; Walter P Blackstock; J Gallo; Simon Lovestone; Michael Hutton; Brian H Anderton
Effects of FTDP-17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3beta identified by mass spectrometry demonstrate certain mutations exert long-range conformational changes.
FEBS letters 2001;493(1):40-4.
2001: Carsten Russ; Simon Lovestone; Matt Baker; Stuart Pickering-Brown; Peter M Andersen; R Furlong; D M A Mann; John F Powell
The extended haplotype of the microtubule associated protein tau gene is not associated with Pick's disease.
Neuroscience letters 2001;299(1-2):156-8.
2001: Simon Lovestone
It takes tau to tangle--the molecular biology of Alzheimer's disease.
Transactions of the Medical Society of London 2001;118():54-6.
2001: TG Mack; Rejith Dayanandan; Marjon van Slegtenhorst; A Whone; Michael Hutton; Simon Lovestone; Brian H Anderton
Tau proteins with frontotemporal dementia-17 mutations have both altered expression levels and phosphorylation profiles in differentiated neuroblastoma cells.
Neuroscience 2001;108(4):701-12.
2001: Jean-Pierre Brion; Brian H Anderton; Michèle Authelet; Rejith Dayanandan; Karelle Leroy; Simon Lovestone; Jean-Noël Octave; Laurent Pradier; Nathalie Touchet; Günter Tremp
Neurofibrillary tangles and tau phosphorylation.
Biochemical Society symposium 2001;(67):81-8.
2001: Brian H Anderton; JC Betts; Walter P Blackstock; Jean-Pierre Brion; S Chapman; J Connell; Rejith Dayanandan; Jean-Marc Gallo; Graham Gibb; Diane P Hanger; Michael Hutton; E Kardalinou; Karelle Leroy; Simon Lovestone; TG Mack; C Hugh Reynolds; Marjon van Slegtenhorst
Sites of phosphorylation in tau and factors affecting their regulation.
Biochemical Society symposium 2001;(67):73-80.
2001: Simon Lovestone; Brian H Anderton; JC Betts; Rejith Dayanandan; Graham Gibb; C Ljungberg; J Pearce
Apolipoprotein E gene and Alzheimer's disease: is tau the link?
Biochemical Society symposium 2001;(67):111-20.
2001: M B Liddell; Simon Lovestone; Michael J Owen
Genetic risk of Alzheimer's disease: advising relatives.
The British journal of psychiatry : the journal of mental science 2001;178(1):7-11.
2000: Amanda Myers; Peter Holmans; Helen Marshall; J Kwon; David Meyer; Dzanan Ramic; Shantia Shears; Jeremy Booth; FW DeVrieze; Richard Crook; Marian Hamshere; Richard Abraham; Nigel Tunstall; Frances Rice; S Carty; S Lillystone; Pat Kehoe; Varuni Rudrasingham; Lesley Jones; Simon Lovestone; Jordi Perez-Tur; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Susceptibility locus for Alzheimer's disease on chromosome 10.
Science (New York, N.Y.) 2000;290(5500):2304-5.
2000: Graham Gibb; J Pearce; JC Betts; Simon Lovestone; Michael M Hoffmann; W Maerz; Walter P Blackstock; Brian H Anderton
Differential effects of apolipoprotein E isoforms on phosphorylation at specific sites on tau by glycogen synthase kinase-3 beta identified by nano-electrospray mass spectrometry.
FEBS letters 2000;485(2-3):99-103.
2000: Jorge Cervilla; Martin Prince; S Joels; Simon Lovestone; Anthony Mann
Long-term predictors of cognitive outcome in a cohort of older people with hypertension.
The British journal of psychiatry : the journal of mental science 2000;177():66-71.
2000: J M Stern; Simon Lovestone
Therapy with the elderly: introducing psychodynamic psychotherapy to the multi-disciplinary team.
International journal of geriatric psychiatry 2000;15(6):500-5.
2000: Nigel Tunstall; Michael J Owen; Julie Williams; Frances Rice; S Carty; S Lillystone; L Fraser; Pat Kehoe; D Neill; Varuni Rudrasingham; P Sham; Simon Lovestone
Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 2000;176():156-9.
2000: Brian H Anderton; Rejith Dayanandan; Richard Killick; Simon Lovestone
Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?
Molecular medicine today 2000;6(2):54-9.
2000: Martin Prince; Simon Lovestone; Jorge Cervilla; Suzanne Joels; John Powell; C Russ; Anthony Mann
The association between APOE and dementia does not seem to be mediated by vascular factors.
Neurology 2000;54(2):397-402.
2000: Karelle Leroy; R Menu; J L Conreur; Rejith Dayanandan; Simon Lovestone; Brian H Anderton; Jean-Pierre Brion
The function of the microtubule-associated protein tau is variably modulated by graded changes in glycogen synthase kinase-3beta activity.
FEBS letters 2000;465(1):34-8.
2000: C Hugh Reynolds; Graham Gibb; Simon Lovestone
Tau phosphorylation both in vitro and in cells.
Methods in molecular medicine 2000;32():375-93.
2000: Orestes Forlenza; J M Spink; Rejith Dayanandan; Brian H Anderton; O F Olesen; Simon Lovestone
Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons.
Journal of neural transmission (Vienna, Austria : 1996) 2000;107(10):1201-12.
1999: Simon Lovestone
Diabetes and dementia: is the brain another site of end-organ damage?
Neurology 1999;53(9):1907-9.
1999: David Cotter; Mrinalini Honavar; Simon Lovestone; L Raymond; Robert Kerwin; Brian H Anderton; Ian Everall
Disturbance of Notch-1 and Wnt signalling proteins in neuroglial balloon cells and abnormal large neurons in focal cortical dysplasia in human cortex.
Acta neuropathologica 1999;98(5):465-72.
1999: Nigel Tunstall; Simon Lovestone
UK Alzheimer's disease genetics consortium.
International journal of geriatric psychiatry 1999;14(9):789-91.
1999: Varuni Rudrasingham; Fabienne Wavrant-De Vrièze; jean-charles lambert; S Chakraverty; Pat Kehoe; Richard Crook; Philippe Amouyel; W Wu; Frances Rice; Jordi Pérez-Tur; Bernard Frigard; John C Morris; S Carty; Ronald C. Petersen; Dominique Cottel; Nigel Tunstall; Peter Holmans; Simon Lovestone; Marie-Christine Chartier-Harlin; Alison Goate; John Hardy; Michael J Owen; Julie Williams
Alpha-2 macroglobulin gene and Alzheimer disease.
Nature genetics 1999;22(1):17-9; author reply 21-2.
1999: Simon Lovestone; D R Davis; M T Webster; Stefanie Kaech; Jean-Pierre Brion; Andrew Matus; Brian H Anderton
Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations.
Biological psychiatry 1999;45(8):995-1003.
1999: Rejith Dayanandan; Marjon van Slegtenhorst; TG Mack; L Ko; Shu-Hui C. Yen; Karelle Leroy; Jean-Pierre Brion; Brian H Anderton; Michael Hutton; Simon Lovestone
Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation.
FEBS letters 1999;446(2-3):228-32.
1999: F Wavrant-DeVrièze; Varuni Rudrasingham; jean-charles lambert; S Chakraverty; Pat Kehoe; Richard Crook; Philippe Amouyel; W Wu; Peter Holmans; Frances Rice; Jordi Pérez-Tur; Bernard Frigard; John C Morris; S Carty; Dominique Cottel; Nigel Tunstall; Simon Lovestone; Ronald C. Petersen; Marie-Christine Chartier-Harlin; Alison Goate; Michael J Owen; Julie Williams; John Hardy
No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease.
Neuroscience letters 1999;262(2):137-9.
1999: Jorge Cervilla; C Russ; C Holmes; KJ Aitchison; C A Smith; John Powell; Simon Lovestone
CYP2D6 polymorphisms in Alzheimer's disease, with and without extrapyramidal signs, showing no apolipoprotein E epsilon 4 effect modification.
Biological psychiatry 1999;45(4):426-9.
1999: Simon Lovestone
Early diagnosis and the clinical genetics of Alzheimer's disease.
Journal of neurology 1999;246(2):69-72.
1999: Pat Kehoe; Fabienne Wavrant De-Vrieze; Richard Crook; W S Wu; Peter Holmans; Iain Fenton; Gillian Spurlock; Nadine Norton; Hywel Williams; Nigel Williams; Simon Lovestone; Jordi Perez-Tur; Michael Hutton; Marie-Christine Chartier-Harlin; Shantia Shears; K Roehl; Jeremy Booth; W Van Voorst; Dzanan Ramic; Julie Williams; Alison Goate; John Hardy; Michael J Owen
A full genome scan for late onset Alzheimer's disease.
Human molecular genetics 1999;8(2):237-45.
1999: Pat Kehoe; C Russ; S McIlory; H Williams; Peter Holmans; C Holmes; D Liolitsa; D Vahidassr; J Powell; B McGleenon; M Liddell; Robert Plomin; Kevin B Dynan; N Williams; Jim Neal; Nigel J Cairns; Gordon K Wilcock; Peter Passmore; Simon Lovestone; Julie Williams; Michael J Owen
Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease.
Nature genetics 1999;21(1):71-2.
1998: Pang-Chui Shaw; A F Davies; Kwok-Fai Lau; MM Garcia-Barcelo; Mary Waye; Simon Lovestone; Christopher C J Miller; Brian H Anderton
Isolation and chromosomal mapping of human glycogen synthase kinase-3 alpha and -3 beta encoding genes.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1998;41(5):720-7.
1998: C Holmes; M J Arranz; John F Powell; D A Collier; Simon Lovestone
5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease.
Human molecular genetics 1998;7(9):1507-9.
1998: W S Wu; Peter Holmans; F Wavrant-DeVrièze; Shantia Shears; Pat Kehoe; Richard Crook; Jeremy Booth; Nigel Williams; Jordi Pérez-Tur; K Roehl; Iain Fenton; Marie-Christine Chartier-Harlin; Simon Lovestone; Julie Williams; Michael Hutton; John Hardy; Michael J Owen; Alison Goate
Genetic studies on chromosome 12 in late-onset Alzheimer disease.
JAMA : the journal of the American Medical Association 1998;280(7):619-22.
1998: Simon Lovestone
Genetics consortiums can offer views facilitating best practice in Alzheimer's disease.
BMJ (Clinical research ed.) 1998;317(7156):471.
1998: David Cotter; Robert Kerwin; S al-Sarraji; Jean-Pierre Brion; A Chadwich; Simon Lovestone; Brian H Anderton; Ian Everall
Abnormalities of Wnt signalling in schizophrenia--evidence for neurodevelopmental abnormality.
Neuroreport 1998;9(7):1379-83.
1998: Carsten Russ; J Powell; Simon Lovestone; C Holmes
K variant of butyrycholinesterase and late-onset Alzheimer's disease.
Lancet 1998;351(9106):881.
1998: N Gormley; M R Rizwan; Simon Lovestone
Clinical predictors of aggressive behaviour in Alzheimer's disease.
International journal of geriatric psychiatry 1998;13(2):109-15.
1998: C Holmes; Carsten Russ; G Kirov; KJ Aitchison; John F Powell; David A Collier; Simon Lovestone
Apolipoprotein E: depressive illness, depressive symptoms, and Alzheimer's disease.
Biological psychiatry 1998;43(3):159-64.
1997: M Philpot; K Lewis; M L Pereria; C Ward; C Holmes; Simon Lovestone; A Fensom; M Seller
Arylsulphatase A pseudodeficiency in vascular dementia and Alzheimer's disease.
Neuroreport 1997;8(11):2613-6.
1997: Simon Lovestone; N Graham; R Howard
Guidelines on drug treatments for Alzheimer's disease.
Lancet 1997;350(9073):232-3.
1997: C Holmes; O Fortenza; J Powell; Simon Lovestone
Do neuroleptic drugs hasten cognitive decline in dementia? Carriers of apolipoprotein E epsilon 4 allele seem particularly susceptible to their effects.
BMJ (Clinical research ed.) 1997;314(7091):1411; author reply 1412.
1997: Simon Lovestone; C Hugh Reynolds
The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes.
Neuroscience 1997;78(2):309-24.
1997: T Li; C Holmes; Pak C Sham; Homero Vallada; J Birkett; G Kirov; K P Lesch; J Powell; Simon Lovestone; David Collier
Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimer's disease.
Neuroreport 1997;8(3):683-6.
1996: C Holmes; R Levy; Declan McLoughlin; J F Powell; Simon Lovestone
Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1996;61(6):580-3.
1996: Ian G McKeith; Douglas Galasko; K Kosaka; Elaine K Perry; dennis dickson; Lawrence A Hansen; David P Salmon; J Lowe; Suzanne S Mirra; E J Byrne; G Lennox; Niall Quinn; J A Edwardson; Paul Geoffrey Ince; C Bergeron; Alistair Burns; Bruce L Miller; Simon Lovestone; D Collerton; E N Jansen; Clive G Ballard; Rob A I de Vos; Gordon K Wilcock; Kurt A Jellinger; Robert H Perry
Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop.
Neurology 1996;47(5):1113-24.
1996: Pat Kehoe; Julie Williams; Peter Holmans; M Liddell; Simon Lovestone; C Holmes; J Powell; Jim Neal; Gordon K Wilcock; Michael J Owen
Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease.
Neuroreport 1996;7(13):2155-8.
1996: Simon Lovestone; C L Hartley; J Pearce; Brian H Anderton
Phosphorylation of tau by glycogen synthase kinase-3 beta in intact mammalian cells: the effects on the organization and stability of microtubules.
Neuroscience 1996;73(4):1145-57.
1996: Simon Lovestone; Gordon K Wilcock; Martin N Rossor; H Cayton; I Ragan
Apolipoprotein E genotyping in Alzheimer's disease. The UK Alzheimer's Disease Genetic consortium.
Lancet 1996;347(9017):1775-6.
1996: Pat Kehoe; Julie Williams; Simon Lovestone; Gordon K Wilcock; Michael J Owen
Presenilin-1 polymorphism and Alzheimer's disease. The UK Alzheimer's Disease Collaborative Group.
Lancet 1996;347(9009):1185.
1996: Simon Lovestone; Brian H Anderton; C Hartley; T G Jensen; A L Jorgensen
The intracellular fate of apolipoprotein E is tau dependent and apoe allele-specific.
Neuroreport 1996;7(5):1005-8.
1996: Simon Lovestone; S Hodgson; P Sham; A M Differ; R Levy
Familial psychiatric presentation of Huntington's disease.
Journal of medical genetics 1996;33(2):128-31.
1995: Simon Lovestone; R Howard
Alzheimer's disease: a treatment in sight?
Journal of neurology, neurosurgery, and psychiatry 1995;59(6):566-7.
1995: M Marks; Simon Lovestone
The role of the father in parental postnatal mental health.
The British journal of medical psychology 1995;68 ( Pt 2)():157-68.
1995: D A Latimer; J M Gallo; Simon Lovestone; Christopher C J Miller; C Hugh Reynolds; B Marquardt; S Stabel; J R Woodgett; Brian H Anderton
Stimulation of MAP kinase by v-raf transformation of fibroblasts fails to induce hyperphosphorylation of transfected tau.
FEBS letters 1995;365(1):42-6.
1995: Brian H Anderton; Jean-Pierre Brion; A M Couck; D R Davis; J M Gallo; Diane P Hanger; Kaetan Ladhani; D A Latimer; C Lewis; Simon Lovestone
Modulation of PHF-like tau phosphorylation in cultured neurones and transfected cells.
Neurobiology of aging 1995;16(3):389-97; discussion 398-402.
1995: C Strong; Brian H Anderton; Robert H Perry; Elaine K Perry; Paul Geoffrey Ince; Simon Lovestone
Abnormally phosphorylated tau protein in senile dementia of Lewy body type and Alzheimer disease: evidence that the disorders are distinct.
Alzheimer disease and associated disorders 1995;9(4):218-22.
1995: Henry Brodaty; M Conneally; S Gauthier; C Jennings; A Lennox; Simon Lovestone
Consensus statement on predictive testing for Alzheimer disease.
Alzheimer disease and associated disorders 1995;9(4):182-7.
1994: Simon Lovestone; C Hugh Reynolds; D Latimer; D R Davis; Brian H Anderton; J M Gallo; Diane P Hanger; S Mulot; B Marquardt; S Stabel
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.
Current biology : CB 1994;4(12):1077-86.
1994: K Ismail; R Howard; Simon Lovestone
Acceptability of electroconvulsive therapy to patients with Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 1994;57(3):383-4.
1993: N Anwar; Simon Lovestone; Michael Cheetham; R Levy; J F Powell
Apolipoprotein E-epsilon 4 allele and Alzheimer's disease.
Lancet 1993;342(8882):1308-9.
1993: Simon Lovestone; R Kumar
Postnatal psychiatric illness: the impact on partners.
The British journal of psychiatry : the journal of mental science 1993;163():210-6.
1993: Simon Lovestone
Periodic psychosis associated with the menstrual cycle and childbirth.
The British journal of psychiatry : the journal of mental science 1993;162():424-5.
1992: Simon Lovestone; Brian H Anderton
Cytoskeletal abnormalities in Alzheimer's disease.
Current opinion in neurology and neurosurgery 1992;5(6):883-8.
1992: Simon Lovestone
Periodic psychosis associated with the menstrual cycle and increased blink rate.
The British journal of psychiatry : the journal of mental science 1992;161():402-4.
1992: K McKenzie; Simon Lovestone
Management of breast cancer.
BMJ (Clinical research ed.) 1992;305(6845):113-4.
1992: R Howard; Simon Lovestone; R Levy
Ernest Saunders: diagnostic dilemma.
BMJ (Clinical research ed.) 1992;304(6841):1568.
1991: Simon Lovestone
Chloroquine-induced mania.
The British journal of psychiatry : the journal of mental science 1991;159():164-5.
1991: Simon Lovestone; T Fahy
Psychological factors in breast cancer.
BMJ (Clinical research ed.) 1991;302(6787):1219-20.
1990: Simon Lovestone
Delusional bovine spongiform encephalopathy.
Lancet 1990;336(8714):565.
1988: Simon Lovestone
Community care: Italian style.
BMJ (Clinical research ed.) 1988;297(6655):1042-3.
1986: Simon Lovestone
The Trieste experience.
Lancet 1986;2(8514):1025-8.