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Joachim Goedhart

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Merel J W Adjobo-Hermans; Arshia Bhageloe; Kevin C Crosby; Joachim Goedhart; Mateusz Putyrski; Carsten Schultz; Laura van Weeren; Theodorus W J Gadella
PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.
David von Stetten; Theodorus W J Gadella; Joachim Goedhart; Marjolaine Noirclerc-Savoye; Antoine Royant
Structure of a fluorescent protein from Aequorea victoria bearing the obligate-monomer mutation A206K.
Joachim Goedhart; Mark A Hink; Linda Joosen; Mickaël Lelimousin; Marjolaine Noirclerc-Savoye; Laura van Weeren; David von Stetten; Theodorus W J Gadella; Antoine Royant
Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.

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2013: Merel J W Adjobo-Hermans; Arshia Bhageloe; Kevin C Crosby; Joachim Goedhart; Mateusz Putyrski; Carsten Schultz; Laura van Weeren; Theodorus W J Gadella
PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.
Cellular signalling 2013;25(1):255-63.
2012: David von Stetten; Theodorus W J Gadella; Joachim Goedhart; Marjolaine Noirclerc-Savoye; Antoine Royant
Structure of a fluorescent protein from Aequorea victoria bearing the obligate-monomer mutation A206K.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 8):878-82.
2012: Joachim Goedhart; Mark A Hink; Linda Joosen; Mickaël Lelimousin; Marjolaine Noirclerc-Savoye; Laura van Weeren; David von Stetten; Theodorus W J Gadella; Antoine Royant
Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.
Nature communications 2012;3():751.
2011: Joachim Goedhart; Theodorus W J Gadella
Bypassing GPCRs with chemical dimerizers.
Chemistry & biology 2011;18(9):1067-8.
2011: Joachim Goedhart; Mark A Hink; Laura van Weeren; Merel J W Adjobo-Hermans; Ies Elzenaar; Theodorus W J Gadella
Quantitative co-expression of proteins at the single cell level--application to a multimeric FRET sensor.
PloS one 2011;6(11):e27321.
2011: Merel J W Adjobo-Hermans; Joachim Goedhart; Erik M M Manders; Saskia Nijmeijer; Stefan Offermanns; Laura van Weeren; Theodorus W J Gadella
Real-time visualization of heterotrimeric G protein Gq activation in living cells.
BMC biology 2011;9():32.
2010: Martijn S Luijsterburg; Gesa von Bornstaedt; Audrey M Gourdin; Antonio Z Politi; Martijn J Moné; Daniël O Warmerdam; Joachim Goedhart; Wim Vermeulen; Roel Van Driel; Thomas Höfer
Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair.
The Journal of cell biology 2010;189(3):445-63.
2010: Joachim Goedhart; Laura van Weeren; Mark A Hink; Norbert O E Vischer; Kees Jalink; Theodorus W J Gadella
Bright cyan fluorescent protein variants identified by fluorescence lifetime screening.
Nature methods 2010;7(2):137-9.
2009: Joop E M Vermeer; Julie M Thole; Joachim Goedhart; Erik Nielsen; Teun Munnik; Theodorus W J Gadella
Imaging phosphatidylinositol 4-phosphate dynamics in living plant cells.
The Plant journal : for cell and molecular biology 2009;57(2):356-72.
2008: Merel J W Adjobo-Hermans; Joachim Goedhart; Theodorus W J Gadella
Regulation of PLCbeta1a membrane anchoring by its substrate phosphatidylinositol (4,5)-bisphosphate.
Journal of cell science 2008;121(Pt 22):3770-7.
2008: Gert-Jan Kremers; Erik B van Munster; Joachim Goedhart; Theodorus W J Gadella
Quantitative lifetime unmixing of multiexponentially decaying fluorophores using single-frequency fluorescence lifetime imaging microscopy.
Biophysical journal 2008;95(1):378-89.
2007: Martijn S Luijsterburg; Joachim Goedhart; Jill Moser; Hanneke Kool; Bart Geverts; Adriaan B Houtsmuller; Leon H F Mullenders; Wim Vermeulen; Roel Van Driel
Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.
Journal of cell science 2007;120(Pt 15):2706-16.
2007: Ekaterina M Merzlyak; Joachim Goedhart; Dmitry Shcherbo; Maria E Bulina; Alexander S Shcheglov; Arkady F Fradkov; Anna Gaintzeva; Konstantin A Lukyanov; Sergey Lukyanov; Theodorus W J Gadella; Dmitriy M Chudakov
Bright monomeric red fluorescent protein with an extended fluorescence lifetime.
Nature methods 2007;4(7):555-7.
2007: Erik B van Munster; Joachim Goedhart; Gert-Jan Kremers; Erik Manders; Theodorus W J Gadella
Combination of a spinning disc confocal unit with frequency-domain fluorescence lifetime imaging microscopy.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2007;71(4):207-14.
2007: Gert-Jan Kremers; Joachim Goedhart; Dave J van den Heuvel; Hans C Gerritsen; Theodorus W J Gadella
Improved green and blue fluorescent proteins for expression in bacteria and mammalian cells.
Biochemistry 2007;46(12):3775-83.
2007: Joachim Goedhart; Joop E M Vermeer; Merel J W Adjobo-Hermans; Laura van Weeren; Theodorus W J Gadella
Sensitive detection of p65 homodimers using red-shifted and fluorescent protein-based FRET couples.
PloS one 2007;2(10):e1011.
2006: Merel J W Adjobo-Hermans; Joachim Goedhart; Theodorus W J Gadella
Plant G protein heterotrimers require dual lipidation motifs of Galpha and Ggamma and do not dissociate upon activation.
Journal of cell science 2006;119(Pt 24):5087-97.
2006: Gert-Jan Kremers; Joachim Goedhart; Erik B van Munster; Theodorus W J Gadella
Cyan and yellow super fluorescent proteins with improved brightness, protein folding, and FRET Förster radius.
Biochemistry 2006;45(21):6570-80.
2005: Carsten Schultz; Andreas Schleifenbaum; Joachim Goedhart; Theodorus W J Gadella
Multiparameter imaging for the analysis of intracellular signaling.
Chembiochem : a European journal of chemical biology 2005;6(8):1323-30.
2005: Joachim Goedhart; Theodorus W J Gadella
Analysis of oligonucleotide annealing by electrophoresis in agarose gels using sodium borate conductive medium.
Analytical biochemistry 2005;343(1):186-7.
2004: Marten Postma; Jeroen Roelofs; Joachim Goedhart; Harriët M Loovers; Antonie J W G Visser; peter van haastert
Sensitization of Dictyostelium chemotaxis by phosphoinositide-3-kinase-mediated self-organizing signalling patches.
Journal of cell science 2004;117(Pt 14):2925-35.
2004: Joachim Goedhart; Theodorus W J Gadella
Photolysis of caged phosphatidic acid induces flagellar excision in Chlamydomonas.
Biochemistry 2004;43(14):4263-71.
2003: Marten Postma; Jeroen Roelofs; Joachim Goedhart; Theodorus W J Gadella; Antonie J W G Visser; peter van haastert
Uniform cAMP stimulation of Dictyostelium cells induces localized patches of signal transduction and pseudopodia.
Molecular biology of the cell 2003;14(12):5019-27.
2003: Pankaj Dhonukshe; Ana M Laxalt; Joachim Goedhart; Theodorus W J Gadella; Teun Munnik
Phospholipase d activation correlates with microtubule reorganization in living plant cells.
The Plant cell 2003;15(11):2666-79.
2003: Joachim Goedhart; Jean-Jacques Bono; Ton Bisseling; Theodorus W J Gadella
Identical accumulation and immobilization of sulfated and nonsulfated Nod factors in host and nonhost root hair cell walls.
Molecular plant-microbe interactions : MPMI 2003;16(10):884-92.
2002: Joachim Goedhart; Jean-Jacques Bono; Theodorus W J Gadella
Rapid colorimetric quantification of lipo-chitooligosaccharides from Mesorhizobium loti and Sinorhizobium meliloti.
Molecular plant-microbe interactions : MPMI 2002;15(9):859-65.
2000: Joachim Goedhart; Mark A Hink; Antonie J W G Visser; Ton Bisseling; Theodorus W J Gadella
In vivo fluorescence correlation microscopy (FCM) reveals accumulation and immobilization of Nod factors in root hair cell walls.
The Plant journal : for cell and molecular biology 2000;21(1):109-19.
1999: Joachim Goedhart; Horst Röhrig; Mark A Hink; Arie van Hoek; Antonie J W G Visser; Ton Bisseling; Theodorus W J Gadella
Nod factors integrate spontaneously in biomembranes and transfer rapidly between membranes and to root hairs, but transbilayer flip-flop does not occur.
Biochemistry 1999;38(33):10898-907.