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Gustavo Baldassarre

Research Profile

Physiology

Anatomy

Chemicals & Drugs

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Publications

TOP 3
Maura Sonego; Barbara Valeri; Marina Bagnoli; Mattia Barbareschi; Barbara Belletti; Silvana Canevari; Vincenzo Canzonieri; Alfonso Colombatti; Alessandra Dall'acqua; Sara D'Andrea; Giannino Del Sal; Giorgio Giorda; Massimo Libra; Francesca Lovat; Sara Lovisa; Delia Mezzanzanica; Loredana Militello; Marco Napoli; Barbara Pivetta; Monica Schiappacassi; Gustavo Baldassarre
Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.
Sara D'Andrea; Linda Fabris; Ilenia Segatto; Andrea Vecchione; Barbara Belletti; Stefania Berton; Vincenzo Canzonieri; Alfonso Colombatti; Gustavo Baldassarre
Stathmin is dispensable for tumor onset in mice.
Monica Schiappacassi; Sara Lovisa; Francesca Lovat; Linda Fabris; Alfonso Colombatti; Barbara Belletti; Gustavo Baldassarre
Role of T198 modification in the regulation of p27(Kip1) protein stability and function.

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All Publications

2013: Maura Sonego; Barbara Valeri; Marina Bagnoli; Mattia Barbareschi; Barbara Belletti; Silvana Canevari; Vincenzo Canzonieri; Alfonso Colombatti; Alessandra Dall'acqua; Sara D'Andrea; Giannino Del Sal; Giorgio Giorda; Massimo Libra; Francesca Lovat; Sara Lovisa; Delia Mezzanzanica; Loredana Militello; Marco Napoli; Barbara Pivetta; Monica Schiappacassi; Gustavo Baldassarre
Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer.
EMBO molecular medicine 2013;5(5):707-22.
2012: Sara D'Andrea; Linda Fabris; Ilenia Segatto; Andrea Vecchione; Barbara Belletti; Stefania Berton; Vincenzo Canzonieri; Alfonso Colombatti; Gustavo Baldassarre
Stathmin is dispensable for tumor onset in mice.
PloS one 2012;7(9):e45561.
2011: Monica Schiappacassi; Sara Lovisa; Francesca Lovat; Linda Fabris; Alfonso Colombatti; Barbara Belletti; Gustavo Baldassarre
Role of T198 modification in the regulation of p27(Kip1) protein stability and function.
PloS one 2011;6(3):e17673.
2010: Barbara Belletti; Ilenia Pellizzari; Stefania Berton; Linda Fabris; Katarina Wolf; Francesca Lovat; Monica Schiappacassi; Sara D'Andrea; Milena S Nicoloso; Sara Lovisa; Maura Sonego; Paola Defilippi; Aldo Vecchione; Alfonso Colombatti; Peter Friedl; Gustavo Baldassarre
p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling.
Molecular and cellular biology 2010;30(9):2229-40.
2009: Aldo Vecchione; Matteo Fassan; V Anesti; Andrea Morrione; Silvia Goldoni; Gustavo Baldassarre; D Byrne; D D'Arca; Juan P Palazzo; J Lloyd; LUCA SCORRANO; Leonard G Gomella; Renato V Iozzo; Raffaele Baffa
MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer.
Oncogene 2009;28(2):257-69.
2008: Fabio Petrocca; Rosa Visone; Mariadele Rapazzotti Onelli; Manisha H Shah; Milena S Nicoloso; Ivana de Martino; Dimitrios Iliopoulos; Emanuela Pilozzi; Chang-gong liu; Massimo Negrini; Luigi Cavazzini; Stefano Volinia; Hansjuerg Alder; Luigi P Ruco; Gustavo Baldassarre; Carlo M Croce; Aldo Vecchione
E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer.
Cancer cell 2008;13(3):272-86.
2007: Aldo Vecchione; Gustavo Baldassarre; Hideshi Ishii; Milena S Nicoloso; Barbara Belletti; Fabio Petrocca; nicola zanesi; Louise Y Y Fong; Sabrina Battista; Daniela Guarnieri; Raffaele Baffa; Hansjuerg Alder; John L Farber; Peter J Donovan; Carlo M Croce
Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.
Cancer cell 2007;11(3):275-89.
2007: Aldo Vecchione; Carlo M Croce; Gustavo Baldassarre
Fez1/Lzts1 a new mitotic regulator implicated in cancer development.
Cell division 2007;2():24.
2006: Monica Fedele; Vincenzo Fidanza; Sabrina Battista; Francesca Pentimalli; Andres J P Klein-Szanto; Rosa Visone; Ivana De Martino; Antonio Curcio; Carmine Morisco; Luigi Del Vecchio; Gustavo Baldassarre; Claudio Arra; Giuseppe Viglietto; Ciro Indolfi; Carlo M Croce; Alfredo Fusco
Haploinsufficiency of the Hmga1 gene causes cardiac hypertrophy and myelo-lymphoproliferative disorders in mice.
Cancer research 2006;66(5):2536-43.
2005: Gustavo Baldassarre; Barbara Belletti; Sabrina Battista; Milena S Nicoloso; Francesca Pentimalli; Monica Fedele; Carlo M Croce; Alfredo Fusco
HMGA1 protein expression sensitizes cells to cisplatin-induced cell death.
Oncogene 2005;24(45):6809-19.
2005: Maria Letizia Motti; Daniela Califano; Gustavo Baldassarre; Angela Celetti; Francesco Merolla; Floriana Forzati; Maria Napolitano; Barbara Tavernise; Alfredo Fusco; Giuseppe Viglietto
Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.
Carcinogenesis 2005;26(6):1021-34.
2005: Monica Fedele; Francesca Pentimalli; Gustavo Baldassarre; Sabrina Battista; Andres J P Klein-Szanto; Lawrence Kenyon; Rosa Visone; Ivana De Martino; Andrea Ciarmiello; Claudio Arra; Giuseppe Viglietto; Carlo M Croce; Alfredo Fusco
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.
Oncogene 2005;24(21):3427-35.
2005: Barbara Belletti; Milena S Nicoloso; Monica Schiappacassi; E Chimienti; S Berton; F Lovat; Alfonso Colombatti; Gustavo Baldassarre
p27(kip1) functional regulation in human cancer: a potential target for therapeutic designs.
Current medicinal chemistry 2005;12(14):1589-605.
2005: Gustavo Baldassarre; Barbara Belletti; Milena S Nicoloso; Monica Schiappacassi; Aldo Vecchione; Paola Spessotto; Andrea Morrione; Vincenzo Canzonieri; Alfonso Colombatti
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion.
Cancer cell 2005;7(1):51-63.
2004: Gustavo Baldassarre; Milena S Nicoloso; Monica Schiappacassi; Emanuela Chimienti; Barbara Belletti
Linking inflammation to cell cycle progression.
Current pharmaceutical design 2004;10(14):1653-66.
2003: Maria Letizia Motti; Angelo Boccia; Barbara Belletti; Paola Bruni; Giancarlo Troncone; Letizia Cito; Mario Monaco; Gennaro Chiappetta; Gustavo Baldassarre; Lucio Palombini; Alfredo Fusco; Giuseppe Viglietto
Critical role of cyclin D3 in TSH-dependent growth of thyrocytes and in hyperproliferative diseases of the thyroid gland.
Oncogene 2003;22(48):7576-86.
2003: Sabrina Battista; Francesca Pentimalli; Gustavo Baldassarre; Monica Fedele; Vincenzo Fidanza; Carlo M Croce; Alfredo Fusco
Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(11):1496-8.
2003: Valeria Masciullo; Gustavo Baldassarre; Francesca Pentimalli; Maria Teresa Berlingieri; Angelo Boccia; Gennaro Chiappetta; Juan P Palazzo; Guidalberto Manfioletti; Vincenzo Giancotti; Giuseppe Viglietto; Giovanni Scambia; Alfredo Fusco
HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas.
Carcinogenesis 2003;24(7):1191-8.
2003: Sanjay Thakur; Tatsuya Nakamura; George Calin; Andrea Russo; Joseph F Tamburrino; Masayoshi Shimizu; Gustavo Baldassarre; Sabrina Battista; Alfredo Fusco; Richard Wassell; Garrett C DuBois; Hansjuerg Alder; Carlo M Croce
Regulation of BRCA1 transcription by specific single-stranded DNA binding factors.
Molecular and cellular biology 2003;23(11):3774-87.
2003: Gustavo Baldassarre; Sabrina Battista; Barbara Belletti; Sanjay Thakur; Francesca Pentimalli; Francesco Trapasso; Monica Fedele; Giovanna Maria Pierantoni; Carlo M Croce; Alfredo Fusco
Negative regulation of BRCA1 gene expression by HMGA1 proteins accounts for the reduced BRCA1 protein levels in sporadic breast carcinoma.
Molecular and cellular biology 2003;23(7):2225-38.
2002: Monica Fedele; Sabrina Battista; Lawrence Kenyon; Gustavo Baldassarre; Vincenzo Fidanza; Andres J P Klein-Szanto; A F Parlow; Rosa Visone; Giovanna Maria Pierantoni; Eric K Outwater; Massimo Santoro; Carlo M Croce; Alfredo Fusco
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.
Oncogene 2002;21(20):3190-8.
2002: Aldo Vecchione; Hideshi Ishii; Gustavo Baldassarre; Pierfrancesco Bassi; Francesco Trapasso; Hansjuerg Alder; Francesco Pagano; Leonard G Gomella; Carlo M Croce; Raffaele Baffa
FEZ1/LZTS1 is down-regulated in high-grade bladder cancer, and its restoration suppresses tumorigenicity in transitional cell carcinoma cells.
The American journal of pathology 2002;160(4):1345-52.
2002: Gustavo Baldassarre; Paola Bruni; Angelo Boccia; Giuliana Salvatore; Rosa Marina Melillo; Maria Letizia Motti; Maria Napolitano; Barbara Belletti; Alfredo Fusco; Massimo Santoro; Giuseppe Viglietto
Glial cell line-derived neurotrophic factor induces proliferative inhibition of NT2/D1 cells through RET-mediated up-regulation of the cyclin-dependent kinase inhibitor p27(kip1).
Oncogene 2002;21(11):1739-49.
2001: Gustavo Baldassarre; M Tucci; G Lembo; F M Pacifico; R Dono; Carmine T Lago; A Barra; C Bianco; Giuseppe Viglietto; D Salomon; M Graziella Persico
A truncated form of teratocarcinoma-derived growth factor-1 (cripto-1) mRNA expressed in human colon carcinoma cell lines and tumors.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2001;22(5):286-93.
2001: Hideshi Ishii; Aldo Vecchione; Yoshiki Murakumo; Gustavo Baldassarre; Shin-ichiro Numata; Francesco Trapasso; Hansjuerg Alder; Raffaele Baffa; Carlo M Croce
FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10374-9.
2001: Gustavo Baldassarre; Monica Fedele; Sabrina Battista; Aldo Vecchione; Andres J P Klein-Szanto; Massimo Santoro; Thomas Waldmann; N Azimi; Carlo M Croce; Alfredo Fusco
Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):7970-5.
2001: Kristoffel R Dumon; Hideshi Ishii; Aldo Vecchione; Francesco Trapasso; Gustavo Baldassarre; F Chakrani; Teresa Druck; E F Rosato; Noel N Williams; Raffaele Baffa; Matthew J During; Kay Huebner; Carlo M Croce
Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer.
Cancer research 2001;61(12):4827-36.
2001: Monica Fedele; Giovanna Maria Pierantoni; Maria Teresa Berlingieri; Sabrina Battista; Gustavo Baldassarre; Nikhil C Munshi; Monica Dentice; Dimitris Thanos; Massimo Santoro; Giuseppe Viglietto; Alfredo Fusco
Overexpression of proteins HMGA1 induces cell cycle deregulation and apoptosis in normal rat thyroid cells.
Cancer research 2001;61(11):4583-90.
2000: Francesco Trapasso; Rodolfo Iuliano; Angelo Boccia; A Stella; Roberta Visconti; Paola Bruni; Gustavo Baldassarre; Massimo Santoro; Giuseppe Viglietto; Alfredo Fusco
Rat protein tyrosine phosphatase eta suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1).
Molecular and cellular biology 2000;20(24):9236-46.
2000: Rodolfo Iuliano; Francesco Trapasso; A Stella; Ilaria Le Pera; R M Melillo; Paola Bruni; Gustavo Baldassarre; Lorenzo Chiariotti; Massimo Santoro; Giuseppe Viglietto; Alfredo Fusco
Pivotal role of the RB family proteins in in vitro thyroid cell transformation.
Experimental cell research 2000;260(2):257-67.
2000: Gustavo Baldassarre; Angelo Boccia; Paola Bruni; C Sandomenico; Maria Vittoria Barone; Stefano Pepe; T Angrisano; Barbara Belletti; Maria Letizia Motti; Alfredo Fusco; Giuseppe Viglietto
Retinoic acid induces neuronal differentiation of embryonal carcinoma cells by reducing proteasome-dependent proteolysis of the cyclin-dependent inhibitor p27.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2000;11(10):517-26.
2000: Gabriella De Vita; Maria Teresa Berlingieri; Roberta Visconti; Maria Domenica Castellone; Giuseppe Viglietto; Gustavo Baldassarre; Mariastella Zannini; A Bellacosa; Philip Tsichlis; Alfredo Fusco; Massimo Santoro
Akt/protein kinase B promotes survival and hormone-independent proliferation of thyroid cells in the absence of dedifferentiating and transforming effects.
Cancer research 2000;60(14):3916-20.
2000: Paola Bruni; Angelo Boccia; Gustavo Baldassarre; Francesco Trapasso; Massimo Santoro; Gennaro Chiappetta; Alfredo Fusco; Giuseppe Viglietto
PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1.
Oncogene 2000;19(28):3146-55.
2000: Giuseppe Viglietto; S Dolci; Paola Bruni; Gustavo Baldassarre; Lorenzo Chiariotti; Rosa Marina Melillo; Giuliana Salvatore; Gennaro Chiappetta; F Sferratore; Alfredo Fusco; Massimo Santoro
Glial cell line-derived neutrotrophic factor and neurturin can act as paracrine growth factors stimulating DNA synthesis of Ret-expressing spermatogonia.
International journal of oncology 2000;16(4):689-94.
1999: Gustavo Baldassarre; Maria Vittoria Barone; Barbara Belletti; C Sandomenico; Paola Bruni; S Spiezia; Angelo Boccia; MT Vento; A Romano; Stefano Pepe; Alfredo Fusco; Giuseppe Viglietto
Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation.
Oncogene 1999;18(46):6241-51.
1999: Gustavo Baldassarre; Barbara Belletti; Paola Bruni; Angelo Boccia; Francesco Trapasso; Francesca Pentimalli; Maria Vittoria Barone; Gennaro Chiappetta; MT Vento; S Spiezia; Alfredo Fusco; Giuseppe Viglietto
Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells.
The Journal of clinical investigation 1999;104(7):865-74.
1999: Barbara Belletti; P Ferraro; Claudio Arra; Gustavo Baldassarre; Paola Bruni; stefania staibano; G De Rosa; Giuliana Salvatore; Alfredo Fusco; M Graziella Persico; Giuseppe Viglietto
Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene.
Oncogene 1999;18(34):4860-9.
1999: Giuseppe Viglietto; Daniela Califano; Paola Bruni; Gustavo Baldassarre; MT Vento; Barbara Belletti; Monica Fedele; Giovanni Santelli; Angelo Boccia; G Manzo; Massimo Santoro; Alfredo Fusco
Regulation of thymosin beta10 expression by TSH and other mitogenic signals in the thyroid gland and in cultured thyrocytes.
European journal of endocrinology / European Federation of Endocrine Societies 1999;140(6):597-607.
1999: B Scognamiglio; Gustavo Baldassarre; C Cassano; M Tucci; N Montuori; R Dono; G Lembo; A Barra; Carmine T Lago; Giuseppe Viglietto; Mariano Rocchi; M Graziella Persico
Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1.
Cytogenetics and cell genetics 1999;84(3-4):220-4.
1997: Gustavo Baldassarre; A Romano; F Armenante; M Rambaldi; I Paoletti; C Sandomenico; Stefano Pepe; stefania staibano; Giuliana Salvatore; Gaetano De Rosa; M Graziella Persico; Giuseppe Viglietto
Expression of teratocarcinoma-derived growth factor-1 (TDGF-1) in testis germ cell tumors and its effects on growth and differentiation of embryonal carcinoma cell line NTERA2/D1.
Oncogene 1997;15(8):927-36.
1997: G Tortora; Vincenzo Damiano; C Bianco; Gustavo Baldassarre; A R Bianco; L Lanfrancone; Pier Giuseppe Pelicci; Fortunato Ciardiello
The RIalpha subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor.
Oncogene 1997;14(8):923-8.
1996: Gustavo Baldassarre; C Bianco; Giampaolo Tortora; A Ruggiero; Mark M Moasser; Ethan Dmitrovsky; Angelo Raffaele Bianco; Fortunato Ciardiello
Transfection with a CRIPTO anti-sense plasmid suppresses endogenous CRIPTO expression and inhibits transformation in a human embryonal carcinoma cell line.
International journal of cancer. Journal international du cancer 1996;66(4):538-43.
1994: Giampaolo Tortora; Stefano Pepe; C Bianco; Vincenzo Damiano; A Ruggiero; Gustavo Baldassarre; C Corbo; Yoon S Cho-Chung; Angelo Raffaele Bianco; Fortunato Ciardiello
Differential effects of protein kinase A sub-units on Chinese-hamster-ovary cell cycle and proliferation.
International journal of cancer. Journal international du cancer 1994;59(5):712-6.
1994: Giampaolo Tortora; Stefano Pepe; C Bianco; Gustavo Baldassarre; Alfredo Budillon; Timothy Clair; Yoon S Cho-Chung; Angelo Raffaele Bianco; Fortunato Ciardiello
The RI alpha subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells.
Oncogene 1994;9(11):3233-40.
1993: Fortunato Ciardiello; Giampaolo Tortora; Stefano Pepe; C Bianco; Gustavo Baldassarre; A Ruggiero; C Bianco; M P Selvam; Angelo Raffaele Bianco
Reduction of RI alpha subunit of cAMP-dependent protein kinase expression induces growth inhibition of human mammary epithelial cells transformed by TGF-alpha, c-Ha-ras, and c-erbB-2 genes.
Annals of the New York Academy of Sciences 1993;698():102-7.
1993: Fortunato Ciardiello; C Bianco; Nicola Normanno; Gustavo Baldassarre; Stefano Pepe; Giampaolo Tortora; Angelo Raffaele Bianco; David S Salomon
Infection with a transforming growth factor alpha anti-sense retroviral expression vector reduces the in vitro growth and transformation of a human colon cancer cell line.
International journal of cancer. Journal international du cancer 1993;54(6):952-8.
1993: Fortunato Ciardiello; Stefano Pepe; C Bianco; Gustavo Baldassarre; A Ruggiero; C Bianco; M P Selvam; Angelo Raffaele Bianco; Giampaolo Tortora
Down-regulation of RI alpha subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes.
International journal of cancer. Journal international du cancer 1993;53(3):438-43.