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Fiorenzo Stirpe

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Fiorenzo Stirpe
Ribosome-inactivating proteins: From toxins to useful proteins.
Lúcia R Bertholdo-Vargas; Juliana Nascimento Martins; Diana Bordin; Mirian Salvador; Alois Eduard Schafer; Neiva Monteiro de Barros; Luigi Barbieri; Fiorenzo Stirpe; Célia R Carlini
Type 1 ribosome-inactivating proteins - entomotoxic, oxidative and genotoxic action on Anticarsia gemmatalis (Hübner) and Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae).
Fiorenzo Stirpe; Andrea Bolognesi; Mauro Bortolotti; Valentina Farini; Chiara Lubelli; Emanuele Pelosi; Letizia Polito; Barbara Dozza; Paola Strocchi; Angela Chambery; Augusto Parente; Luigi Barbieri
Characterization of highly toxic type 2 ribosome-inactivating proteins from Adenia lanceolata and Adenia stenodactyla (Passifloraceae).

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All Publications

2013: Fiorenzo Stirpe
Ribosome-inactivating proteins: From toxins to useful proteins.
Toxicon : official journal of the International Society on Toxinology 2013;67():12-6.
2009: Lúcia R Bertholdo-Vargas; Juliana Nascimento Martins; Diana Bordin; Mirian Salvador; Alois Eduard Schafer; Neiva Monteiro de Barros; Luigi Barbieri; Fiorenzo Stirpe; Célia R Carlini
Type 1 ribosome-inactivating proteins - entomotoxic, oxidative and genotoxic action on Anticarsia gemmatalis (Hübner) and Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae).
Journal of insect physiology 2009;55(1):51-8.
2007: Fiorenzo Stirpe; Andrea Bolognesi; Mauro Bortolotti; Valentina Farini; Chiara Lubelli; Emanuele Pelosi; Letizia Polito; Barbara Dozza; Paola Strocchi; Angela Chambery; Augusto Parente; Luigi Barbieri
Characterization of highly toxic type 2 ribosome-inactivating proteins from Adenia lanceolata and Adenia stenodactyla (Passifloraceae).
Toxicon : official journal of the International Society on Toxinology 2007;50(1):94-105.
2007: Barbara Monti; Christian D'Alessandro; Valentina Farini; Andrea Bolognesi; Elisabetta Polazzi; Antonio Contestabile; Fiorenzo Stirpe; Maria Giulia Battelli
In vitro and in vivo toxicity of type 2 ribosome-inactivating proteins lanceolin and stenodactylin on glial and neuronal cells.
Neurotoxicology 2007;28(3):637-44.
2007: Angela Chambery; Valeria Severino; Fiorenzo Stirpe; Augusto Parente
Cloning and expression of the B chain of volkensin, type 2 ribosome inactivating protein from Adenia volkensii harms: co-folding with the A chain for heterodimer reconstitution.
Protein expression and purification 2007;51(2):209-15.
2006: Angela Chambery; Anna de Donato; Andrea Bolognesi; Letizia Polito; Fiorenzo Stirpe; Augusto Parente
Sequence determination of lychnin, a type 1 ribosome-inactivating protein from Lychnis chalcedonica seeds.
Biological chemistry 2006;387(9):1261-6.
2006: Fiorenzo Stirpe; Maria Giulia Battelli
Ribosome-inactivating proteins: progress and problems.
Cellular and molecular life sciences : CMLS 2006;63(16):1850-66.
2006: Chiara Lubelli; Alexandros Chatgilialoglu; Andrea Bolognesi; Paola Strocchi; Marco Colombatti; Fiorenzo Stirpe
Detection of ricin and other ribosome-inactivating proteins by an immuno-polymerase chain reaction assay.
Analytical biochemistry 2006;355(1):102-9.
2006: Luigi Barbieri; Letizia Polito; Andrea Bolognesi; Marialibera Ciani; Emanuele Pelosi; Valentina Farini; Ajay K Jha; Neelam Sharma; Jorge M Vivanco; Angela Chambery; Augusto Parente; Fiorenzo Stirpe
Ribosome-inactivating proteins in edible plants and purification and characterization of a new ribosome-inactivating protein from Cucurbita moschata.
Biochimica et biophysica acta 2006;1760(5):783-92.
2005: Emanuele Pelosi; Chiara Lubelli; Letizia Polito; Luigi Barbieri; Andrea Bolognesi; Fiorenzo Stirpe
Ribosome-inactivating proteins and other lectins from Adenia (Passifloraceae).
Toxicon : official journal of the International Society on Toxinology 2005;46(6):658-63.
2005: Andrea Bolognesi; Letizia Polito; Valentina Farini; Mauro Bortolotti; Pier Luigi Tazzari; Marina Ratta; A Ravaioli; Alberto L Horenstein; Fiorenzo Stirpe; Maria Giulia Battelli; Fabio Malavasi
CD38 as a target of IB4 mAb carrying saporin-S6: design of an immunotoxin for ex vivo depletion of hematological CD38+ neoplasia.
Journal of biological regulators and homeostatic agents 2005;19(3-4):145-52.
2005: Maria Giulia Battelli; Letizia Polito; Federica Falà; Silvia Musiani; Pier Luigi Tazzari; Fiorenzo Stirpe; Andrea Bolognesi
Toxicity of xanthine oxidoreductase to malignant B lymphocytes.
Journal of biological regulators and homeostatic agents 2005;19(3-4):120-9.
2005: Paola Strocchi; Barbara Dozza; Irene Pecorella; Michela Fresina; Emilio Campos; Fiorenzo Stirpe
Lesions caused by ricin applied to rabbit eyes.
Investigative ophthalmology & visual science 2005;46(4):1113-6.
2005: Piero Sestili; Roberta R Alfieri; Domenica Carnicelli; Chiara Martinelli; Luigi Barbieri; Fiorenzo Stirpe; Mara A Bonelli; Pier Giorgio Petronini; Maurizio Brigotti
Shiga toxin 1 and ricin inhibit the repair of H2O2-induced DNA single strand breaks in cultured mammalian cells.
DNA repair 2005;4(2):271-7.
2005: Simona Fermani; Giuseppe Falini; Alberto Ripamonti; Letizia Polito; Fiorenzo Stirpe; Andrea Bolognesi
The 1.4 anstroms structure of dianthin 30 indicates a role of surface potential at the active site of type 1 ribosome inactivating proteins.
Journal of structural biology 2005;149(2):204-12.
2004: Fiorenzo Stirpe
Twenty years of hunting for proteins with Carlo Alfonso Rossi.
The Italian journal of biochemistry 2004;53(4):164-8.
2004: Fiorenzo Stirpe
Ribosome-inactivating proteins.
Toxicon : official journal of the International Society on Toxinology 2004;44(4):371-83.
2004: Maria Giulia Battelli; Silvia Musiani; L Buonamici; Spartaco Santi; Massimo Riccio; Nadir M Maraldi; Tomás Girbés; Fiorenzo Stirpe
Interaction of volkensin with HeLa cells: binding, uptake, intracellular localization, degradation and exocytosis.
Cellular and molecular life sciences : CMLS 2004;61(15):1975-84.
2004: Letizia Polito; Andrea Bolognesi; Pier Luigi Tazzari; Valentina Farini; Chiara Lubelli; Pier Luigi Zinzani; Francesca Ricci; Fiorenzo Stirpe
The conjugate Rituximab/saporin-S6 completely inhibits clonogenic growth of CD20-expressing cells and produces a synergistic toxic effect with Fludarabine.
Leukemia 2004;18(7):1215-22.
2004: Tomás Girbés; J Miguel Ferreras; F Javier Arias; Fiorenzo Stirpe
Description, distribution, activity and phylogenetic relationship of ribosome-inactivating proteins in plants, fungi and bacteria.
Mini reviews in medicinal chemistry 2004;4(5):461-76.
2004: Luigi Barbieri; Marialibera Ciani; Tomás Girbés; Wang-Yi Liu; Els J M Van Damme; Willy J Peumans; Fiorenzo Stirpe
Enzymatic activity of toxic and non-toxic type 2 ribosome-inactivating proteins.
FEBS letters 2004;563(1-3):219-22.
2004: Giulio L Palmisano; Pier Luigi Tazzari; E Cozzi; Andrea Bolognesi; Letizia Polito; Michela Seveso; E Ancona; Francesca Ricci; Roberto Conte; Fiorenzo Stirpe; Giovanni Battista Ferrara; Maria Pia Pistillo
Expression of CTLA-4 in nonhuman primate lymphocytes and its use as a potential target for specific immunotoxin-mediated apoptosis: results of in vitro studies.
Clinical and experimental immunology 2004;135(2):259-66.
2004: Angela Chambery; Antimo Di Maro; Maurilia M Monti; Fiorenzo Stirpe; Augusto Parente
Volkensin from Adenia volkensii Harms (kilyambiti plant), a type 2 ribosome-inactivating protein.
European journal of biochemistry / FEBS 2004;271(1):108-17.
2004: Neelam Sharma; Sang-Wook Park; Ramarao Vepachedu; Luigi Barbieri; Marialibera Ciani; Fiorenzo Stirpe; Brett J Savary; Jorge M Vivanco
Isolation and characterization of an RIP (ribosome-inactivating protein)-like protein from tobacco with dual enzymatic activity.
Plant physiology 2004;134(1):171-81.
2003: Simona Fermani; Giuseppe Falini; Alberto Ripamonti; Andrea Bolognesi; Letizia Polito; Fiorenzo Stirpe
Crystallization and preliminary X-ray diffraction analysis of two ribosome-inactivating proteins: lychnin and dianthin 30.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 7):1227-9.
2003: Luigi Barbieri; Maurizio Brigotti; Paolo Perocco; Domenica Carnicelli; Marialibera Ciani; Laura Mercatali; Fiorenzo Stirpe
Ribosome-inactivating proteins depurinate poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase and have transforming activity for 3T3 fibroblasts.
FEBS letters 2003;538(1-3):178-82.
2003: Maria Pia Pistillo; Pier Luigi Tazzari; Giulio L Palmisano; Ivana Pierri; Andrea Bolognesi; Francesca Ferlito; Paolo Capanni; Letizia Polito; Marina Ratta; Stefano Pileri; Milena Piccioli; Giuseppe Basso; Laura Rissotto; Roberto Conte; marco gobbi; Fiorenzo Stirpe; Giovanni Battista Ferrara
CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells.
Blood 2003;101(1):202-9.
2002: Fiorenzo Stirpe; Matteo Ravaioli; Maria Giulia Battelli; Silvia Musiani; Gian Luca Grazi
Xanthine oxidoreductase activity in human liver disease.
The American journal of gastroenterology 2002;97(8):2079-85.
2002: Andrea Bolognesi; Letizia Polito; Chiara Lubelli; Luigi Barbieri; Augusto Parente; Fiorenzo Stirpe
Ribosome-inactivating and adenine polynucleotide glycosylase activities in Mirabilis jalapa L. tissues.
The Journal of biological chemistry 2002;277(16):13709-16.
2002: Wen-Jun He; Shuang Tang; Wang-Yi Liu; Fiorenzo Stirpe
Nonspecific deadenylation on sarcin/ricin domain RNA catalyzed by gelonin under acidic conditions.
Archives of biochemistry and biophysics 2002;399(2):181-7.
2002: Marcel T den Hartog; Chiara Lubelli; Louis Boon; Sijmie Heerkens; Antonio Ortiz Buijsse; Mark de Boer; Fiorenzo Stirpe
Cloning and expression of cDNA coding for bouganin.
European journal of biochemistry / FEBS 2002;269(6):1772-9.
2002: Maurizio Brigotti; Roberta R Alfieri; Piero Sestili; Mara A Bonelli; Pier Giorgio Petronini; Andrea Guidarelli; Luigi Barbieri; Fiorenzo Stirpe; Simonetta Sperti
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(3):365-72.
2002: Emilio C Campos; Costantino Schiavi; Andrea Bolognesi; Costantino Bellusci; Chiara Lubelli; Alberta Duca; Letizia Polito; Konstantinos Poulas; Socrates J Tzartos; Fiorenzo Stirpe
Selective lesions of rabbit extraocular muscles injected with the anti-AChR immunotoxin saporin-mAb 73.
Current eye research 2002;24(1):58-65.
2001: Maria Giulia Battelli; Silvia Musiani; Pier Luigi Tazzari; Fiorenzo Stirpe
Oxidative stress to human lymphocytes by xanthine oxidoreductase activity.
Free radical research 2001;35(6):665-79.
2001: Pier Luigi Tazzari; Letizia Polito; Andrea Bolognesi; Maria Pia Pistillo; Paolo Capanni; Giulio L Palmisano; Roberto M Lemoli; A Curti; L Biancone; G Camussi; Roberto Conte; Giovanni Battista Ferrara; Fiorenzo Stirpe
Immunotoxins containing recombinant anti-CTLA-4 single-chain fragment variable antibodies and saporin: in vitro results and in vivo effects in an acute rejection model.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4222-9.
2001: Luigi Barbieri; P Valbonesi; M Bondioli; M L Alvarez; Paola Dal Monte; M P Landini; Fiorenzo Stirpe
Adenine glycosylase activity in mammalian tissues: an equivalent of ribosome-inactivating proteins.
FEBS letters 2001;505(1):196-7.
2001: Maria Giulia Battelli; Silvia Musiani; Barbara Monti; L Buonamici; M Sparapani; Antonio Contestabile; Fiorenzo Stirpe
Ricin toxicity to microglial and monocytic cells.
Neurochemistry international 2001;39(2):83-93.
2001: Maria Giulia Battelli; Silvia Musiani; Marco Valgimigli; Laura Gramantieri; F Tomassoni; Luigi Bolondi; Fiorenzo Stirpe
Serum xanthine oxidase in human liver disease.
The American journal of gastroenterology 2001;96(4):1194-9.
2001: Maria Pia Pistillo; Pier Luigi Tazzari; Fiorenzo Stirpe; Andrea Bolognesi; Letizia Polito; Paolo Capanni; Claudio Pioli; Lucia Gatta; Vanessa Ubaldi; Gino Doria; Roberto Conte; Giovanni Battista Ferrara
Anti-CTLA-4 human scFv antibodies prevent T-cell activation in transplantation.
Transplantation proceedings 2001;33(1-2):285-7.
2001: Luigi Barbieri; Andrea Bolognesi; Fiorenzo Stirpe
Purification and conjugation of type 1 ribosome-inactivating proteins.
Methods in molecular biology (Clifton, N.J.) 2001;166():71-85.
2001: Antimo Di Maro; Pasquale Ferranti; M Mastronicola; Letizia Polito; Andrea Bolognesi; Fiorenzo Stirpe; Antonio Malorni; Augusto Parente
Reliable sequence determination of ribosome- inactivating proteins by combining electrospray mass spectrometry and Edman degradation.
Journal of mass spectrometry : JMS 2001;36(1):38-46.
2000: Luigi Barbieri; P Valbonesi; F Righi; Giampaolo Zuccheri; F Monti; P Gorini; B Samorí; Fiorenzo Stirpe
Polynucleotide:Adenosine glycosidase is the sole activity of ribosome-inactivating proteins on DNA.
Journal of biochemistry 2000;128(5):883-9.
2000: Andrea Bolognesi; Letizia Polito; Pier Luigi Tazzari; Roberto M Lemoli; Chiara Lubelli; Miriam Fogli; Louis Boon; Mark de Boer; Fiorenzo Stirpe
In vitro anti-tumour activity of anti-CD80 and anti-CD86 immunotoxins containing type 1 ribosome-inactivating proteins.
British journal of haematology 2000;110(2):351-61.
2000: Luigi Barbieri; P Valbonesi; M Govoni; A Pession; Fiorenzo Stirpe
Polynucleotide:adenosine glycosidase activity of saporin-L1: effect on various forms of mammalian DNA.
Biochimica et biophysica acta 2000;1480(1-2):258-66.
2000: Luigi Barbieri; Andrea Bolognesi; P Valbonesi; Letizia Polito; F Olivieri; Fiorenzo Stirpe
Polynucleotide: adenosine glycosidase activity of immunotoxins containing ribosome-inactivating proteins.
Journal of drug targeting 2000;8(5):281-8.
1999: Maria Giulia Battelli; A Abbondanza; Silvia Musiani; L Buonamici; Paola Strocchi; Pier Luigi Tazzari; Laura Gramantieri; Fiorenzo Stirpe
Determination of xanthine oxidase in human serum by a competitive enzyme-linked immunosorbent assay (ELISA).
Clinica chimica acta; international journal of clinical chemistry 1999;281(1-2):147-58.
1999: Antimo Di Maro; P Valbonesi; Andrea Bolognesi; Fiorenzo Stirpe; P De Luca; G Siniscalco Gigliano; luciano gaudio; Pasquale Delli Bovi; Pasquale Ferranti; Antonio Malorni; Augusto Parente
Isolation and characterization of four type-1 ribosome-inactivating proteins, with polynucleotide:adenosine glycosidase activity, from leaves of Phytolacca dioica L.
Planta 1999;208(1):125-31.
1999: P Valbonesi; Luigi Barbieri; Andrea Bolognesi; E Bonora; Letizia Polito; Fiorenzo Stirpe
Preparation of highly purified momordin II without ribonuclease activity.
Life sciences 1999;65(14):1485-91.
1998: Maurizio Brigotti; Luigi Barbieri; P Valbonesi; Fiorenzo Stirpe; Lorenzo Montanaro; Simonetta Sperti
A rapid and sensitive method to measure the enzymatic activity of ribosome-inactivating proteins.
Nucleic acids research 1998;26(18):4306-7.
1998: Luigi Barbieri; P Valbonesi; Maurizio Brigotti; Lorenzo Montanaro; Fiorenzo Stirpe; Simonetta Sperti
Shiga-like toxin I is a polynucleotide:adenosine glycosidase.
Molecular microbiology 1998;29(2):661-2.
1998: Gennaro Raimo; Alessandro Arcucci; Luigi Barbieri; P Valbonesi; Mariorosario Masullo; Fiorenzo Stirpe; Vincenzo Bocchini
The effect of ribosome-inactivating proteins on the ribosome from the hyperthermophilic archaeon Sulfolobus solfataricus.
Biochemistry and molecular biology international 1998;44(4):665-72.
1998: Andrea Bolognesi; Pier Luigi Tazzari; F Olivieri; Letizia Polito; Roberto M Lemoli; Adelmo Terenzi; Laura Pasqualucci; Brunangelo Falini; Fiorenzo Stirpe
Evaluation of immunotoxins containing single-chain ribosome-inactivating proteins and an anti-CD22 monoclonal antibody (OM124): in vitro and in vivo studies.
British journal of haematology 1998;101(1):179-88.
1998: Maria Giulia Battelli; Andrea Bolognesi; F Olivieri; Letizia Polito; Fiorenzo Stirpe
Different sensitivity of CD30+ cell lines to Ber-H2/saporin-S6 immunotoxin.
Journal of drug targeting 1998;5(3):181-91.
1997: Andrea Bolognesi; Letizia Polito; F Olivieri; P Valbonesi; Luigi Barbieri; Maria Giulia Battelli; M V Carusi; E Benvenuto; F Del Vecchio Blanco; Antimo Di Maro; Augusto Parente; M Di Loreto; Fiorenzo Stirpe
New ribosome-inactivating proteins with polynucleotide:adenosine glycosidase and antiviral activities from Basella rubra L. and bougainvillea spectabilis Willd.
Planta 1997;203(4):422-9.
1997: M Sparapani; L Buonamici; Elisabetta Ciani; Maria Giulia Battelli; G Ceccarelli; Fiorenzo Stirpe; Antonio Contestabile
Toxicity of ricin and volkensin, two ribosome-inactivating proteins, to microglia, astrocyte, and neuron cultures.
Glia 1997;20(3):203-9.
1997: Maria Giulia Battelli; Luigi Barbieri; Andrea Bolognesi; L Buonamici; P Valbonesi; Letizia Polito; Els J M Van Damme; Willy J Peumans; Fiorenzo Stirpe
Ribosome-inactivating lectins with polynucleotide:adenosine glycosidase activity.
FEBS letters 1997;408(3):355-9.
1997: Luigi Barbieri; P Valbonesi; E Bonora; P Gorini; Andrea Bolognesi; Fiorenzo Stirpe
Polynucleotide:adenosine glycosidase activity of ribosome-inactivating proteins: effect on DNA, RNA and poly(A).
Nucleic acids research 1997;25(3):518-22.
1997: Maria Giulia Battelli; Lucía Citores; L Buonamici; J Miguel Ferreras; FM de Benito; Fiorenzo Stirpe; Tomás Girbés
Toxicity and cytotoxicity of nigrin b, a two-chain ribosome-inactivating protein from Sambucus nigra: comparison with ricin.
Archives of toxicology 1997;71(6):360-4.
1997: A M Di Massimo; M Di Loreto; A Pacilli; Giuseppe Raucci; Laura D'Alatri; Alfonso Mele; Andrea Bolognesi; Letizia Polito; Fiorenzo Stirpe; Rita De Santis
Immunoconjugates made of an anti-EGF receptor monoclonal antibody and type 1 ribosome-inactivating proteins from Saponaria ocymoides or Vaccaria pyramidata.
British journal of cancer 1997;75(6):822-8.
1996: F Olivieri; Vivek Prasad; P Valbonesi; S Srivastava; P Ghosal-Chowdhury; Luigi Barbieri; Andrea Bolognesi; Fiorenzo Stirpe
A systemic antiviral resistance-inducing protein isolated from Clerodendrum inerme Gaertn. is a polynucleotide:adenosine glycosidase (ribosome-inactivating protein).
FEBS letters 1996;396(2-3):132-4.
1996: Andrea Bolognesi; Pier Luigi Tazzari; F Olivieri; Letizia Polito; Brunangelo Falini; Fiorenzo Stirpe
Induction of apoptosis by ribosome-inactivating proteins and related immunotoxins.
International journal of cancer. Journal international du cancer 1996;68(3):349-55.
1996: Luigi Barbieri; P Valbonesi; P Gorini; A Pession; Fiorenzo Stirpe
Polynucleotide: adenosine glycosidase activity of saporin-L1: effect on DNA, RNA and poly(A).
The Biochemical journal 1996;319 ( Pt 2)():507-13.
1996: Wim C Vooijs; J Post; John Wijdenes; H J Schuurman; Andrea Bolognesi; Letizia Polito; Fiorenzo Stirpe; bert bast; Gijsbert C De Gast
Efficacy and toxicity of plasma-cell-reactive monoclonal antibodies B-B2 and B-B4 and their immunotoxins.
Cancer immunology, immunotherapy : CII 1996;42(6):319-28.
1996: Fiorenzo Stirpe; Luigi Barbieri; P Gorini; P Valbonesi; Andrea Bolognesi; Letizia Polito
Activities associated with the presence of ribosome-inactivating proteins increase in senescent and stressed leaves.
FEBS letters 1996;382(3):309-12.
1996: Adelmo Terenzi; Andrea Bolognesi; Laura Pasqualucci; L Flenghi; S Pileri; Harald Stein; M Kadin; B Bigerna; Letizia Polito; Pier Luigi Tazzari; Massimo F Martelli; Fiorenzo Stirpe; Brunangelo Falini
Anti-CD30 (BER=H2) immunotoxins containing the type-1 ribosome-inactivating proteins momordin and PAP-S (pokeweed antiviral protein from seeds) display powerful antitumour activity against CD30+ tumour cells in vitro and in SCID mice.
British journal of haematology 1996;92(4):872-9.
1996: Maria Giulia Battelli; Letizia Polito; Andrea Bolognesi; L Lafleur; Y Fradet; Fiorenzo Stirpe
Toxicity of ribosome-inactivating proteins-containing immunotoxins to a human bladder carcinoma cell line.
International journal of cancer. Journal international du cancer 1996;65(4):485-90.
1996: Maria Giulia Battelli; L Buonamici; Letizia Polito; Andrea Bolognesi; Fiorenzo Stirpe
Hepatoxicity of ricin, saporin or a saporin immunotoxin: xanthine oxidase activity in rat liver and blood serum.
Virchows Archiv : an international journal of pathology 1996;427(5):529-35.
1995: Laura Pasqualucci; L Flenghi; Adelmo Terenzi; Andrea Bolognesi; Fiorenzo Stirpe; B Bigerna; Brunangelo Falini
Immunotoxin therapy of hematological malignancies.
Haematologica 1995;80(6):546-56.
1995: Sabrina Sforzini; Andrea Bolognesi; Raffaella Meazza; S Marciano; Pier Luigi Tazzari; Harald Stein; Fiorenzo Stirpe; Silvano Ferrini
Targeting of type 1 ribosome-inactivating proteins to CD30+ or CD25+ hematologic neoplasias by bispecific antibodies.
Journal of hematotherapy 1995;4(5):429-32.
1995: D Cevolani; Paola Strocchi; M Bentivoglio; Fiorenzo Stirpe
Suicide retrograde transport of volkensin in cerebellar afferents: direct evidence, neuronal lesions and comparison with ricin.
Brain research 1995;689(2):163-71.
1995: Sabrina Sforzini; Andrea Bolognesi; Raffaella Meazza; S Marciano; Patrizia Casalini; H Dürkop; Pier Luigi Tazzari; Harald Stein; Fiorenzo Stirpe; Silvano Ferrini
Differential sensitivity of CD30+ neoplastic cells to gelonin delivered by anti-CD30/anti-gelonin bispecific antibodies.
British journal of haematology 1995;90(3):572-7.
1995: Maria Giulia Battelli; L Buonamici; A Abbondanza; Marco Virgili; Antonio Contestabile; Fiorenzo Stirpe
Excitotoxic increase of xanthine dehydrogenase and xanthine oxidase in the rat olfactory cortex.
Brain research. Developmental brain research 1995;86(1-2):340-4.
1995: Laura Pasqualucci; M Wasik; B A Teicher; L Flenghi; Andrea Bolognesi; Fiorenzo Stirpe; Letizia Polito; Brunangelo Falini; M E Kadin
Antitumor activity of anti-CD30 immunotoxin (Ber-H2/saporin) in vitro and in severe combined immunodeficiency disease mice xenografted with human CD30+ anaplastic large-cell lymphoma.
Blood 1995;85(8):2139-46.
1995: Andrea Bolognesi; F Olivieri; Maria Giulia Battelli; Luigi Barbieri; A I Falasca; Augusto Parente; F Del Vecchio Blanco; Fiorenzo Stirpe
Ribosome-inactivating proteins (RNA N-glycosidases) from the seeds of Saponaria ocymoides and Vaccaria pyramidata.
European journal of biochemistry / FEBS 1995;228(3):935-40.
1995: Andrea Bolognesi; Pier Luigi Tazzari; G Legname; F Olivieri; Daniela Modena; Roberto Conte; Fiorenzo Stirpe
Anti-CD30 immunotoxins with native and recombinant dianthin 30.
Cancer immunology, immunotherapy : CII 1995;40(2):109-14.
1995: Brunangelo Falini; S Pileri; G Pizzolo; H Dürkop; L Flenghi; Fiorenzo Stirpe; Massimo F Martelli; Harald Stein
CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy.
Blood 1995;85(1):1-14.
1994: Luigi Barbieri; P Gorini; P Valbonesi; P Castiglioni; Fiorenzo Stirpe
Unexpected activity of saporins.
Nature 1994;372(6507):624.
1994: Maria Giulia Battelli; L Buonamici; Andrea Bolognesi; Fiorenzo Stirpe
In vivo and in vitro uptake of an anti-CD30/saporin immunotoxin by rat liver parenchymal and nonparenchymal cells.
Hepatology (Baltimore, Md.) 1994;20(4 Pt 1):940-7.
1994: Roberto M Lemoli; Pier Luigi Tazzari; A Fortuna; Andrea Bolognesi; S C Gulati; Fiorenzo Stirpe; Sante Tura
Positive selection of hematopoietic CD34+ stem cells provides 'indirect purging' of CD34- lymphoid cells and the purging efficiency is increased by anti-CD2 and anti-CD30 immunotoxins.
Bone marrow transplantation 1994;13(4):465-71.
1994: Pier Luigi Tazzari; Andrea Bolognesi; Daniela de Totero; R M Lemoli; A Fortuna; Roberto Conte; M J Crumpton; Fiorenzo Stirpe
Immunotoxins containing saporin linked to different CD2 monoclonal antibodies: in vitro evaluation.
British journal of haematology 1994;86(1):97-105.
1993: Luigi Barbieri; Maria Giulia Battelli; Fiorenzo Stirpe
Ribosome-inactivating proteins from plants.
Biochimica et biophysica acta 1993;1154(3-4):237-82.
1993: Augusto Parente; P De Luca; Andrea Bolognesi; Luigi Barbieri; Maria Giulia Battelli; A Abbondanza; M J Sande; G S Gigliano; Pier Luigi Tazzari; Fiorenzo Stirpe
Purification and partial characterization of single-chain ribosome-inactivating proteins from the seeds of Phytolacca dioica L.
Biochimica et biophysica acta 1993;1216(1):43-9.
1993: J Miguel Ferreras; Luigi Barbieri; Tomás Girbés; Maria Giulia Battelli; M A Rojo; F J Arias; M A Rocher; F Soriano; E Mendéz; Fiorenzo Stirpe
Distribution and properties of major ribosome-inactivating proteins (28 S rRNA N-glycosidases) of the plant Saponaria officinalis L. (Caryophyllaceae).
Biochimica et biophysica acta 1993;1216(1):31-42.
1993: Antonio Contestabile; Fiorenzo Stirpe
Ribosome-inactivating proteins from plants as agents for suicide transport and immunolesioning in the nervous system.
The European journal of neuroscience 1993;5(10):1292-301.
1993: Federico Licastro; M C Morini; Andrea Bolognesi; Fiorenzo Stirpe
Ricin induces the production of tumour necrosis factor-alpha and interleukin-1 beta by human peripheral-blood mononuclear cells.
The Biochemical journal 1993;294 ( Pt 2)():517-20.
1993: Fiorenzo Stirpe; Federico Licastro; M C Morini; Augusto Parente; G Savino; A Abbondanza; Andrea Bolognesi; A I Falasca; C A Rossi
Purification and partial characterization of a mitogenic lectin from the latex of Euphorbia marginata.
Biochimica et biophysica acta 1993;1158(1):33-9.
1993: Pier Luigi Tazzari; S Zhang; Q Chen; Sabrina Sforzini; Andrea Bolognesi; Fiorenzo Stirpe; H Xie; A Moretta; Silvano Ferrini
Targeting of saporin to CD25-positive normal and neoplastic lymphocytes by an anti-saporin/anti-CD25 bispecific monoclonal antibody: in vitro evaluation.
British journal of cancer 1993;67(6):1248-53.
1993: Federico Licastro; M C Morini; O Kretz; G Dirheimer; Edmond CREPPY; Fiorenzo Stirpe
Mitogenic activity and immunological properties of bolesatine, a lectin isolated from the mushroom Boletus satanas Lenz.
The International journal of biochemistry 1993;25(5):789-92.
1993: G Porro; Andrea Bolognesi; P Caretto; G Gromo; P Lento; G Mistza; T Sciumbata; Fiorenzo Stirpe; Daniela Modena
In vitro and in vivo properties of an anti-CD5-momordin immunotoxin on normal and neoplastic T lymphocytes.
Cancer immunology, immunotherapy : CII 1993;36(5):346-50.
1992: Paola Strocchi; Luigi Barbieri; Fiorenzo Stirpe
Immunological properties of ribosome-inactivating proteins and a saporin immunotoxin.
Journal of immunological methods 1992;155(1):57-63.
1992: Andrea Bolognesi; Pier Luigi Tazzari; Cristina Tassi; G Gromo; marco gobbi; Fiorenzo Stirpe
A comparison of anti-lymphocyte immunotoxins containing different ribosome-inactivating proteins and antibodies.
Clinical and experimental immunology 1992;89(3):341-6.
1992: Luigi Barbieri; J Miguel Ferreras; A Barraco; P Ricci; Fiorenzo Stirpe
Some ribosome-inactivating proteins depurinate ribosomal RNA at multiple sites.
The Biochemical journal 1992;286 ( Pt 1)():1-4.
1992: Pier Luigi Tazzari; Andrea Bolognesi; Daniela de Totero; S Pileri; Roberto Conte; J Wijdenes; P Hervé; Marco Soria; Fiorenzo Stirpe; marco gobbi
B-B10 (anti-CD25)-saporin immunotoxin--a possible tool in graft-versus-host disease treatment.
Transplantation 1992;54(2):351-6.
1992: Maria Giulia Battelli; V Montacuti; Fiorenzo Stirpe
High sensitivity of cultured human trophoblasts to ribosome-inactivating proteins.
Experimental cell research 1992;201(1):109-12.
1992: Maria Giulia Battelli; A Abbondanza; Fiorenzo Stirpe
Effects of hypoxia and ethanol on xanthine oxidase of isolated rat hepatocytes: conversion from D to O form and leakage from cells.
Chemico-biological interactions 1992;83(1):73-84.
1992: Maria Giulia Battelli; A Abbondanza; Pier Luigi Tazzari; Andrea Bolognesi; Roberto M Lemoli; Fiorenzo Stirpe
T lymphocyte killing by a xanthine-oxidase-containing immunotoxin.
Cancer immunology, immunotherapy : CII 1992;35(6):421-5.
1991: C Ferrari; Luigi Barbieri; Fiorenzo Stirpe
Effects of plant ribosome-inactivating proteins on ribosomes from Musca domestica.
Comparative biochemistry and physiology. B, Comparative biochemistry 1991;100(2):223-7.
1990: Luigi Barbieri; Maria Giulia Battelli; Fiorenzo Stirpe
Blood clearance and organ distribution and tissue concentration of native, homopolymerized and IgG-conjugated ribosome-inactivating proteins.
Xenobiotica; the fate of foreign compounds in biological systems 1990;20(12):1331-41.
1990: Andrea Bolognesi; Luigi Barbieri; A Abbondanza; A I Falasca; Domenica Carnicelli; Maria Giulia Battelli; Fiorenzo Stirpe
Purification and properties of new ribosome-inactivating proteins with RNA N-glycosidase activity.
Biochimica et biophysica acta 1990;1087(3):293-302.
1990: Maria Giulia Battelli; Luigi Barbieri; Fiorenzo Stirpe
Toxicity of, and histological lesions caused by, ribosome-inactivating proteins, their IgG-conjugates, and their homopolymers.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1990;98(7):585-93.
1990: A Dinota; Pier Luigi Tazzari; A Abbondanza; Maria Giulia Battelli; marco gobbi; Fiorenzo Stirpe
Bone marrow purging by a xanthine oxidase-antibody conjugate.
Bone marrow transplantation 1990;6(1):31-6.
1989: Andrea Bolognesi; Luigi Barbieri; Domenica Carnicelli; A Abbondanza; P Cenini; A I Falasca; A Dinota; Fiorenzo Stirpe
Purification and properties of a new ribosome-inactivating protein with RNA N-glycosidase activity suitable for immunotoxin preparation from the seeds of Momordica cochinchinensis.
Biochimica et biophysica acta 1989;993(2-3):287-92.
1989: A Dinota; Luigi Barbieri; marco gobbi; Pier Luigi Tazzari; Simonetta Rizzi; Andrea Bontadini; Andrea Bolognesi; Sante Tura; Fiorenzo Stirpe
An immunotoxin containing momordin suitable for bone marrow purging in multiple myeloma patients.
British journal of cancer 1989;60(3):315-9.
1989: Luigi Barbieri; Andrea Bolognesi; A Dinota; D A Lappi; Marco Soria; Pier Luigi Tazzari; Fiorenzo Stirpe
Selective killing of CD4+ and CD8+ cells with immunotoxins containing saporin.
Scandinavian journal of immunology 1989;30(3):369-72.
1989: Pier Luigi Tazzari; Maria Giulia Battelli; A Abbondanza; A Dinota; Simonetta Rizzi; marco gobbi; Fiorenzo Stirpe
Targeting of a plasma cell line with a conjugate containing xanthine oxidase and the monoclonal antibody 62B1.
Transplantation 1989;48(1):119-22.
1989: A I Falasca; A Abbondanza; Luigi Barbieri; Andrea Bolognesi; C A Rossi; Fiorenzo Stirpe
Purification and partial characterization of a lectin from the seeds of Trichosanthes kirilowii Maximowicz.
FEBS letters 1989;246(1-2):159-62.
1989: L Barbieri; A Dinota; marco gobbi; P L Tazzari; Simonetta Rizzi; Andrea Bontadini; Roberto M Lemoli; S Tura; Fiorenzo Stirpe
Immunotoxins containing saporin 6 and monoclonal antibodies recognizing plasma cell-associated antigens: effects on target cells and on normal myeloid precursors (CFU-GM).
European journal of haematology 1989;42(3):238-45.
1989: Luigi Barbieri; Andrea Bolognesi; P Cenini; A I Falasca; A Minghetti; L Garofano; A Guicciardi; D Lappi; S P Miller; Fiorenzo Stirpe
Ribosome-inactivating proteins from plant cells in culture.
The Biochemical journal 1989;257(3):801-7.
1988: Fiorenzo Stirpe; E J Wawrzynczak; A N Brown; R E Knyba; G J Watson; Luigi Barbieri; Philip E Thorpe
Selective cytotoxic activity of immunotoxins composed of a monoclonal anti-Thy 1.1 antibody and the ribosome-inactivating proteins bryodin and momordin.
British journal of cancer 1988;58(5):558-61.
1988: Pierre Casellas; Danielle Dussossoy; A I Falasca; Luigi Barbieri; J C Guillemot; Pascual Ferrara; Andrea Bolognesi; P Cenini; Fiorenzo Stirpe
Trichokirin, a ribosome-inactivating protein from the seeds of Trichosanthes kirilowii Maximowicz. Purification, partial characterization and use for preparation of immunotoxins.
European journal of biochemistry / FEBS 1988;176(3):581-8.
1988: P Cenini; Andrea Bolognesi; Fiorenzo Stirpe
Ribosome-inactivating proteins from plants inhibit ribosome activity of Trypanosoma and Leishmania.
The Journal of protozoology 1988;35(3):384-7.
1988: Maria Giulia Battelli; A Abbondanza; Pier Luigi Tazzari; A Dinota; Simonetta Rizzi; G Grassi; marco gobbi; Fiorenzo Stirpe
Selective cytotoxicity of an oxygen-radical-generating enzyme conjugated to a monoclonal antibody.
Clinical and experimental immunology 1988;73(1):128-33.
1987: P Cenini; Maria Giulia Battelli; Andrea Bolognesi; Fiorenzo Stirpe; C L Villemez
Effect of ribosome-inactivating proteins on ribosomes from Tetrahymena pyriformis and Acanthamoeba castellanii.
Biochemical and biophysical research communications 1987;148(2):521-7.
1987: Fiorenzo Stirpe; Massimo Derenzini; Luigi Barbieri; Fulvia Farabegoli; A N Brown; P P Knowles; Philip E Thorpe
Hepatotoxicity of immunotoxins made with saporin, a ribosome-inactivating protein from Saponaria officinalis.
Virchows Archiv. B, Cell pathology including molecular pathology 1987;53(5):259-71.
1986: Fiorenzo Stirpe; Luigi Barbieri; Maria Giulia Battelli; A I Falasca; A Abbondanza; E Lorenzoni; W A Stevens
Bryodin, a ribosome-inactivating protein from the roots of Bryonia dioica L. (white bryony).
The Biochemical journal 1986;240(3):659-65.
1985: Fiorenzo Stirpe; Luigi Barbieri; A Abbondanza; A I Falasca; A N Brown; K Sandvig; S Olsnes; A Pihl
Properties of volkensin, a toxic lectin from Adenia volkensii.
The Journal of biological chemistry 1985;260(27):14589-95.
1985: Philip E Thorpe; A N Brown; J A Bremner; B M Foxwell; Fiorenzo Stirpe
An immunotoxin composed of monoclonal anti-Thy 1.1 antibody and a ribosome-inactivating protein from Saponaria officinalis: potent antitumor effects in vitro and in vivo.
Journal of the National Cancer Institute 1985;75(1):151-9.
1985: Philip E Thorpe; S I Detre; B M Foxwell; A N Brown; D N Skilleter; G Wilson; J A Forrester; Fiorenzo Stirpe
Modification of the carbohydrate in ricin with metaperiodate-cyanoborohydride mixtures. Effects on toxicity and in vivo distribution.
European journal of biochemistry / FEBS 1985;147(1):197-206.
1983: Fiorenzo Stirpe; Anna Gasperi-Campani; Luigi Barbieri; A Falasca; A Abbondanza; W A Stevens
Ribosome-inactivating proteins from the seeds of Saponaria officinalis L. (soapwort), of Agrostemma githago L. (corn cockle) and of Asparagus officinalis L. (asparagus), and from the latex of Hura crepitans L. (sandbox tree).
The Biochemical journal 1983;216(3):617-25.
1983: Luigi Barbieri; A Falasca; C Franceschi; F Licastro; C A Rossi; Fiorenzo Stirpe
Purification and properties of two lectins from the latex of the euphorbiaceous plants Hura crepitans L. (sand-box tree) and Euphorbia characias L. (Mediterranean spurge).
The Biochemical journal 1983;215(3):433-9.
1982: A Falasca; A Gasperi-Campani; A Abbondanza; Luigi Barbieri; Fiorenzo Stirpe
Properties of the ribosome-inactivating proteins gelonin, Momordica charantia inhibitor, and dianthins.
The Biochemical journal 1982;207(3):505-9.
1981: Philip E Thorpe; A N Brown; W C Ross; A J Cumber; S I Detre; D C Edwards; A J Davies; Fiorenzo Stirpe
Cytotoxicity acquired by conjugation of an anti-Thy1.1 monoclonal antibody and the ribosome-inactivating protein, gelonin.
European journal of biochemistry / FEBS 1981;116(3):447-54.
1980: A Falasca; C Franceschi; C A Rossi; Fiorenzo Stirpe
Mitogenic and haemagglutinating properties of a lectinpurified from Hura crepitans seeds.
Biochimica et biophysica acta 1980;632(1):95-105.
1980: Luigi Barbieri; M Zamboni; E Lorenzoni; L Montanaro; Simonetta Sperti; Fiorenzo Stirpe
Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon).
The Biochemical journal 1980;186(2):443-52.
1980: Luigi Barbieri; M Zamboni; L Montanaro; Simonetta Sperti; Fiorenzo Stirpe
Purification and properties of different forms of modeccin, the toxin of Adenia digitata. Separation of subunits with inhibitory and lectin activity.
The Biochemical journal 1980;185(1):203-10.