Floris Lafeber

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Vos Petra; Interma Femke; van El Benno; DeGroot Jeroen; Bijlsma J W J; Lafeber Floris; Mastbergen Simon
Does loading influence the severity of cartilage degeneration in the canine Groove-model of OA?
Hartgring Sarita A Y; van Roon Joel A G; Wenting-van Wijk Marion; Jacobs Kim M G; Jahangier Zalima N; Willis Cynthia R; Bijlsma Johannes W J; Lafeber Floris P J G
Elevated expression of interleukin-7 receptor in inflamed joints mediates interleukin-7-induced immune activation in rheumatoid arthritis.
Custers R J H; Saris D B F; Dhert W J A; Verbout A J; van Rijen M H P; Mastbergen S C; Lafeber F P J G; Creemers L B
Articular cartilage degeneration following the treatment of focal cartilage defects with ceramic metal implants and compared with microfracture.

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All Publications

2009: Vos Petra; Interma Femke; van El Benno; DeGroot Jeroen; Bijlsma J W J; Lafeber Floris; Mastbergen Simon
Does loading influence the severity of cartilage degeneration in the canine Groove-model of OA?
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2009;27(10):1332-8.
2009: Hartgring Sarita A Y; van Roon Joel A G; Wenting-van Wijk Marion; Jacobs Kim M G; Jahangier Zalima N; Willis Cynthia R; Bijlsma Johannes W J; Lafeber Floris P J G
Elevated expression of interleukin-7 receptor in inflamed joints mediates interleukin-7-induced immune activation in rheumatoid arthritis.
Arthritis and rheumatism 2009;60(9):2595-605.
2009: Custers R J H; Saris D B F; Dhert W J A; Verbout A J; van Rijen M H P; Mastbergen S C; Lafeber F P J G; Creemers L B
Articular cartilage degeneration following the treatment of focal cartilage defects with ceramic metal implants and compared with microfracture.
The Journal of bone and joint surgery. American volume 2009;91(4):900-10.
2009: Jansen N W D; Roosendaal G; Wenting M J G; Bijlsma J W J; Theobald M; Hazewinkel H A W; Lafeber F P J G
Very rapid clearance after a joint bleed in the canine knee cannot prevent adverse effects on cartilage and synovial tissue.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2009;17(4):433-40.
2009: Jansen Nathalie W D; Roosendaal Goris; Lundin Björn; Heijnen Lily; Mauser-Bunschoten Evelien; Bijlsma Johannes W J; Theobald Matthias; Lafeber Floris P J G
The combination of the biomarkers urinary C-terminal telopeptide of type II collagen, serum cartilage oligomeric matrix protein, and serum chondroitin sulfate 846 reflects cartilage damage in hemophilic arthropathy.
Arthritis and rheumatism 2009;60(1):290-8.
2008: Jansen Nathalie W D; Roosendaal Goris; Lafeber Floris P J G
Understanding haemophilic arthropathy: an exploration of current open issues.
British journal of haematology 2008;143(5):632-40.
2008: Roosendaal G; Jansen N W D; Schutgens R; Lafeber F P J G
Haemophilic arthropathy: the importance of the earliest haemarthroses and consequences for treatment.
Haemophilia : the official journal of the World Federation of Hemophilia 2008;14 Suppl 6():4-10.
2008: Intema Femke; DeGroot Jeroen; Elshof Bram; Vianen Marieke E; Yocum Sue; Zuurmond Annemarie; Mastbergen Simon C; Lafeber Floris P
The canine bilateral groove model of osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2008;26(11):1471-7.
2008: Frost-Christensen L N; Mastbergen S C; Vianen M E; Hartog A; DeGroot J; Voorhout G; van Wees A M C; Lafeber F P J G; Hazewinkel H A W
Degeneration, inflammation, regeneration, and pain/disability in dogs following destabilization or articular cartilage grooving of the stifle joint.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2008;16(11):1327-35.
2008: Jansen Nathalie W D; Roosendaal Goris; Hooiveld Michel J J; Bijlsma Johannes W J; van Roon Joël A G; Theobald Matthias; Lafeber Floris P J G
Interleukin-10 protects against blood-induced joint damage.
British journal of haematology 2008;142(6):953-61.
2008: Jansen N W D; Vincken K L; Marijnissen A C A; Lundin B; Heijnen L; Roosendaal G; Pettersson H; Lafeber F P J G
Digital scoring of haemophilic arthropathy using radiographs is feasible.
Haemophilia : the official journal of the World Federation of Hemophilia 2008;14(5):999-1006.
2008: Mastbergen S C; Pollmeier M; Fischer L; Vianen M E; Lafeber F P J G
The groove model of osteoarthritis applied to the ovine fetlock joint.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2008;16(8):919-28.
2008: Broere Femke; Wieten Lotte; Klein Koerkamp Elles I; van Roon Joel A G; Guichelaar Teun; Lafeber Floris P J G; van Eden Willem
Oral or nasal antigen induces regulatory T cells that suppress arthritis and proliferation of arthritogenic T cells in joint draining lymph nodes.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):899-906.
2008: Lafeber F P J G; Miossec P; Valentino L A
Physiopathology of haemophilic arthropathy.
Haemophilia : the official journal of the World Federation of Hemophilia 2008;14 Suppl 4():3-9.
2008: Bijlsma Johannes W J; Lafeber Floris P J G
Glucosamine sulfate in osteoarthritis: the jury is still out.
Annals of internal medicine 2008;148(4):315-6.
2008: Marijnissen A C A; Vincken K L; Vos P A J M; Saris D B F; Viergever M A; Bijlsma J W J; Bartels L W; Lafeber F P J G
Knee Images Digital Analysis (KIDA): a novel method to quantify individual radiographic features of knee osteoarthritis in detail.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2008;16(2):234-43.
2008: Wijngaarden S; van de Winkel J G J; Bijlsma J W J; Lafeber F P J G; van Roon J A G
Treatment of rheumatoid arthritis patients with anti-TNF-alpha monoclonal antibody is accompanied by down-regulation of the activating Fcgamma receptor I on monocytes.
Clinical and experimental rheumatology 2008;26(1):89-95.
2008: Mastbergen S C; Bijlsma J W J; Lafeber F P J G
Synthesis and release of human cartilage matrix proteoglycans are differently regulated by nitric oxide and prostaglandin-E2.
Annals of the rheumatic diseases 2008;67(1):52-8.
2008: van Roon Joel A G; Lafeber Floris P J G
Role of interleukin-7 in degenerative and inflammatory joint diseases.
Arthritis research & therapy 2008;10(2):107.
2008: Sniekers Yvonne H; Intema Femke; Lafeber Floris P J G; van Osch Gerjo J V M; van Leeuwen Johannes P T M; Weinans Harrie; Mastbergen Simon C
A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models.
BMC musculoskeletal disorders 2008;9():20.
2007: Roosendaal G; Lafeber F P J G
[Prophylactic treatment with clotting factor to prevent joint damage in patients with severe haemophilia: costs versus benefits]
Nederlands tijdschrift voor geneeskunde 2007;151(47):2606-8.
2007: Kamphorst Jurre J; van der Heijden Rob; DeGroot Jeroen; Lafeber Floris P J G; Reijmers Theo H; van El Benno; Tjaden Ubbo R; van der Greef Jan; Hankemeier Thomas
Profiling of endogenous peptides in human synovial fluid by NanoLC-MS: method validation and peptide identification.
Journal of proteome research 2007;6(11):4388-96.
2007: van Roon Joel A G; Hartgring Sarita A Y; Wenting-van Wijk Marion; Jacobs Kim M G; Tak Paul-Peter; Bijlsma Johannes W J; Lafeber Floris P J G
Persistence of interleukin 7 activity and levels on tumour necrosis factor alpha blockade in patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2007;66(5):664-9.
2007: van Amelsfort Jocea M R; van Roon Joel A G; Noordegraaf Madelon; Jacobs Kim M G; Bijlsma Johannes W J; Lafeber Floris P J G; Taams Leonie S
Proinflammatory mediator-induced reversal of CD4+,CD25+ regulatory T cell-mediated suppression in rheumatoid arthritis.
Arthritis and rheumatism 2007;56(3):732-42.
2007: Jansen Nathalie W D; Roosendaal Goris; Bijlsma Johannes W J; Degroot Jeroen; Lafeber Floris P J G
Exposure of human cartilage tissue to low concentrations of blood for a short period of time leads to prolonged cartilage damage: an in vitro study.
Arthritis and rheumatism 2007;56(1):199-207.
2006: Hartgring S A Y; Bijlsma J W J; Lafeber F P J G; van Roon J A G
Interleukin-7 induced immunopathology in arthritis.
Annals of the rheumatic diseases 2006;65 Suppl 3():iii69-74.
2006: van Roon Joel A G; Bijlsma Johannes W J; Lafeber Floris P J G
Diversity of regulatory T cells to control arthritis.
Best practice & research. Clinical rheumatology 2006;20(5):897-913.
2006: Jahangier Z N; Jacobs K M G; Bijlsma J W J; Lafeber F P J G
Radiation synovectomy with yttrium-90 for persisting arthritis has direct harmful effects on human cartilage that cannot be prevented by co-administration of glucocorticoids: an in vitro study.
Annals of the rheumatic diseases 2006;65(10):1384-9.
2006: Jahangier Z N; Jacobs J W G; Kraan M C; Wenting M J G; Smeets T J; Bijlsma J W J; Lafeber F P J G; Tak P P
Pretreatment macrophage infiltration of the synovium predicts the clinical effect of both radiation synovectomy and intra-articular glucocorticoids.
Annals of the rheumatic diseases 2006;65(10):1286-92.
2006: Lafeber Floris P J G; Intema Femke; Van Roermund Peter M; Marijnissen Anne C A
Unloading joints to treat osteoarthritis, including joint distraction.
Current opinion in rheumatology 2006;18(5):519-25.
2006: Roosendaal G; Lafeber F P
Pathogenesis of haemophilic arthropathy.
Haemophilia : the official journal of the World Federation of Hemophilia 2006;12 Suppl 3():117-21.
2006: Mastbergen S C; Marijnissen A C; Vianen M E; Zoer B; van Roermund P M; Bijlsma J W; Lafeber F P
Inhibition of COX-2 by celecoxib in the canine groove model of osteoarthritis.
Rheumatology (Oxford, England) 2006;45(4):405-13.
2006: Steenvoorden Marjan M C; Huizinga Tom W J; Verzijl Nicole; Bank Ruud A; Ronday H Karel; Luning Hilco A F; Lafeber Floris P J G; Toes René E M; DeGroot Jeroen
Activation of receptor for advanced glycation end products in osteoarthritis leads to increased stimulation of chondrocytes and synoviocytes.
Arthritis and rheumatism 2006;54(1):253-63.
2006: Mastbergen Simon C; Marijnissen Anne C; Vianen Marieke E; van Roermund Peter M; Bijlsma Johannes W; Lafeber Floris P
The canine 'groove' model of osteoarthritis is more than simply the expression of surgically applied damage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2006;14(1):39-46.
2006: Verstappen S M M; Poole A R; Ionescu M; King L E; Abrahamowicz M; Hofman D M; Bijlsma J W J; Lafeber F P J G;
Radiographic joint damage in rheumatoid arthritis is associated with differences in cartilage turnover and can be predicted by serum biomarkers: an evaluation from 1 to 4 years after diagnosis.
Arthritis research & therapy 2006;8(1):R31.
2006: Mastbergen Simon C; Jansen Nathalie W D; Bijlsma Johannes W J; Lafeber Floris P J G
Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study.
Arthritis research & therapy 2006;8(1):R2.
2005: Jahangier Zalima N; Jacobs Johannes W G; Lafeber Floris P J G; Moolenburgh Jan D; Swen Wijnand A A; Bruyn George A W; Griep Ed N; ter Borg Evert-J; Bijlsma Johannes W J
Is radiation synovectomy for arthritis of the knee more effective than intraarticular treatment with glucocorticoids? Results of an eighteen-month, randomized, double-blind, placebo-controlled, crossover trial.
Arthritis and rheumatism 2005;52(11):3391-402.
2005: van Woerkom J M; Kruize A A; Wenting-van Wijk M J G; Knol E; Bihari I C; Jacobs J W G; Bijlsma J W J; Lafeber F P J G; van Roon J A G
Salivary gland and peripheral blood T helper 1 and 2 cell activity in Sjögren's syndrome compared with non-Sjögren's sicca syndrome.
Annals of the rheumatic diseases 2005;64(10):1474-9.
2005: Ploegmakers J J W; van Roermund P M; van Melkebeek J; Lammens J; Bijlsma J W J; Lafeber F P J G; Marijnissen A C A
Prolonged clinical benefit from joint distraction in the treatment of ankle osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2005;13(7):582-8.
2005: van Roon Joel A G; Verweij Marieke C; Wijk Marion Wenting-van; Jacobs Kim M G; Bijlsma Johannes W J; Lafeber Floris P J G
Increased intraarticular interleukin-7 in rheumatoid arthritis patients stimulates cell contact-dependent activation of CD4(+) T cells and macrophages.
Arthritis and rheumatism 2005;52(6):1700-10.
2005: Mastbergen S C; Bijlsma J W; Lafeber F P
Selective COX-2 inhibition is favorable to human early and late-stage osteoarthritic cartilage: a human in vitro study.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2005;13(6):519-26.
2005: Wijngaarden S; van Roon J A G; van de Winkel J G J; Bijlsma J W J; Lafeber F P J G
Down-regulation of activating Fcgamma receptors on monocytes of patients with rheumatoid arthritis upon methotrexate treatment.
Rheumatology (Oxford, England) 2005;44(6):729-34.
2005: van Roon J A G; Bijlsma J W J; van de Winkel J G J; Lafeber F P J G
Depletion of synovial macrophages in rheumatoid arthritis by an anti-FcgammaRI-calicheamicin immunoconjugate.
Annals of the rheumatic diseases 2005;64(6):865-70.
2005: Taams Leonie S; van Amelsfort Jocea M R; Tiemessen Machteld M; Jacobs Kim M G; de Jong Esther C; Akbar Arne N; Bijlsma Johannes W J; Lafeber Floris P J G
Modulation of monocyte/macrophage function by human CD4+CD25+ regulatory T cells.
Human immunology 2005;66(3):222-30.
2004: Wijngaarden Siska; van de Winkel Jan G J; Jacobs Kim M G; Bijlsma Johannes W J; Lafeber Floris P J G; van Roon Joel A G
A shift in the balance of inhibitory and activating Fcgamma receptors on monocytes toward the inhibitory Fcgamma receptor IIb is associated with prevention of monocyte activation in rheumatoid arthritis.
Arthritis and rheumatism 2004;50(12):3878-87.
2004: van Amelsfort Jocea M R; Jacobs Kim M G; Bijlsma Johannes W J; Lafeber Floris P J G; Taams Leonie S
CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid.
Arthritis and rheumatism 2004;50(9):2775-85.
2004: Hooiveld Michel J J; Roosendaal Goris; Jacobs Kim M G; Vianen Marieke E; van den Berg H Marijke; Bijlsma Johannes W J; Lafeber Floris P J G
Initiation of degenerative joint damage by experimental bleeding combined with loading of the joint: a possible mechanism of hemophilic arthropathy.
Arthritis and rheumatism 2004;50(6):2024-31.
2004: DeGroot Jeroen; Verzijl Nicole; Wenting-van Wijk Marion J G; Jacobs Kim M G; Van El Benno; Van Roermund Peter M; Bank Ruud A; Bijlsma Johannes W J; TeKoppele Johan M; Lafeber Floris P J G
Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis.
Arthritis and rheumatism 2004;50(4):1207-15.
2003: Marijnissen Anne C A; van Roermund Peter M; van Melkebeek Jan; Lafeber Floris P J G
Clinical benefit of joint distraction in the treatment of ankle osteoarthritis.
Foot and ankle clinics 2003;8(2):335-46.
2003: ter Steege Jessica; Vianen Marieke; van Bilsen Jolanda; Bijlsma Johannes; Lafeber Floris; Wauben Marca
Identification of self-epitopes recognized by T cells in rheumatoid arthritis demonstrates matrix metalloproteinases as a novel T cell target.
The Journal of rheumatology 2003;30(6):1147-56.
2003: Hooiveld M J J; Roosendaal G; van den Berg H M; Bijlsma J W J; Lafeber F P J G
Haemoglobin-derived iron-dependent hydroxyl radical formation in blood-induced joint damage: an in vitro study.
Rheumatology (Oxford, England) 2003;42(6):784-90.
2003: van Roon Joel A G; van Vuuren Anneke J; Wijngaarden Siska; Jacobs Kim M G; Bijlsma Johannes W J; Lafeber Floris P J G; Thepen Theo; van de Winkel Jan G J
Selective elimination of synovial inflammatory macrophages in rheumatoid arthritis by an Fcgamma receptor I-directed immunotoxin.
Arthritis and rheumatism 2003;48(5):1229-38.
2003: Wijngaarden S; van Roon J A G; Bijlsma J W J; van de Winkel J G J; Lafeber F P J G
Fcgamma receptor expression levels on monocytes are elevated in rheumatoid arthritis patients with high erythrocyte sedimentation rate who do not use anti-rheumatic drugs.
Rheumatology (Oxford, England) 2003;42(5):681-8.
2003: Marijnissen A C A; Lafeber F P J G
Re: E. B. Hunziker. Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. Osteoarthritis and Cartilage 2002; 10:432-63.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2003;11(4):300-1; author reply 302-4.
2003: van Roon Joel; Wijngaarden Siska; Lafeber Floris P J G; Damen Cora; van de Winkel Jan; Bijlsma Johannes W J
Interleukin 10 treatment of patients with rheumatoid arthritis enhances Fc gamma receptor expression on monocytes and responsiveness to immune complex stimulation.
The Journal of rheumatology 2003;30(4):648-51.
2003: Huisman A M; Siewertsz van Everdingen A A; Wenting M J G; Lafeber F; van Reesema D R Siewertsz; Jacobs J W G; Bijlsma J W J
Glucocorticoid receptor up-regulation in early rheumatoid arthritis treated with low dose prednisone or placebo.
Clinical and experimental rheumatology 2003;21(2):217-20.
2003: Hooiveld Michel; Roosendaal Goris; Wenting Marion; van den Berg Marijke; Bijlsma Johannes; Lafeber Floris
Short-term exposure of cartilage to blood results in chondrocyte apoptosis.
The American journal of pathology 2003;162(3):943-51.
2003: Roosendaal Goris; Lafeber Floris P J G
Blood-induced joint damage in hemophilia.
Seminars in thrombosis and hemostasis 2003;29(1):37-42.
2003: Hooiveld Michel J J; Roosendaal Goris; Vianen Marieke E; van den Berg H Marijke; Bijlsma Johannes W J; Lafeber Floris P J G
Immature articular cartilage is more susceptible to blood-induced damage than mature articular cartilage: an in vivo animal study.
Arthritis and rheumatism 2003;48(2):396-403.
2003: Hooiveld Michel; Roosendaal Goris; Vianen Marieke; van den Berg Marijke; Bijlsma Johannes; Lafeber Floris
Blood-induced joint damage: longterm effects in vitro and in vivo.
The Journal of rheumatology 2003;30(2):339-44.
2003: van Roon J A G; Glaudemans K A F M; Bijlsma J W J; Lafeber F P J G
Interleukin 7 stimulates tumour necrosis factor alpha and Th1 cytokine production in joints of patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2003;62(2):113-9.
2003: van Roon Joël A G; Glaudemans Catharina A F M; Bijlsma Johannes W J; Lafeber Floris P J G
Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients.
Arthritis research & therapy 2003;5(5):R269-76.
2002: Marijnissen Anne C A; Van Roermund Peter M; Van Melkebeek Jan; Schenk Willem; Verbout Abraham J; Bijlsma Johannes W J; Lafeber Floris P J G
Clinical benefit of joint distraction in the treatment of severe osteoarthritis of the ankle: proof of concept in an open prospective study and in a randomized controlled study.
Arthritis and rheumatism 2002;46(11):2893-902.
2002: van Roermund Peter M; Marijnissen Anne C A; Lafeber Floris P J G
Joint distraction as an alternative for the treatment of osteoarthritis.
Foot and ankle clinics 2002;7(3):515-27.
2002: van Roon Joel A G; Bijlsma Johannes W J; Lafeber Floris P J G
Suppression of inflammation and joint destruction in rheumatoid arthritis may require a concerted action of Th2 cytokines.
Current opinion in investigational drugs (London, England : 2000) 2002;3(7):1011-6.
2002: Mastbergen S C; Lafeber F P J G; Bijlsma J W J
Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage.
Rheumatology (Oxford, England) 2002;41(7):801-8.
2002: Taams Leonie S; Vukmanovic-Stejic Milica; Smith Jay; Dunne Padraic J; Fletcher Jean M; Plunkett Fiona J; Ebeling Saskia B; Lombardi Giovanna; Rustin Malcolm H; Bijlsma Johannes W J; Lafeber Floris P J G; Salmon Mike; Akbar Arne N
Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.
European journal of immunology 2002;32(6):1621-30.
2002: Huisman A Margriet; Van Everdingen A Amalia; Wenting Marion J G; Siewertsz Van Reesema Dick R; Lafeber Floris P J G; Jacobs Johannes W G; Bijlsma Johannes W J
Glucocorticoid receptor downregulation in early diagnosed rheumatoid arthritis.
Annals of the New York Academy of Sciences 2002;966():64-7.
2002: Marijnissen A C A; van Roermund P M; Verzijl N; Tekoppele J M; Bijlsma J W J; Lafeber F P J G
Steady progression of osteoarthritic features in the canine groove model.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(4):282-9.
2002: Marijnissen A C A; van Roermund P M; TeKoppele J M; Bijlsma J W J; Lafeber F P J G
The canine 'groove' model, compared with the ACLT model of osteoarthritis.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(2):145-55.
2002: Bank R A; Verzijl N; Lafeber F P J G; Tekoppele J M
Putative role of lysyl hydroxylation and pyridinoline cross-linking during adolescence in the occurrence of osteoarthritis at old age.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(2):127-34.
2002: Verzijl Nicole; DeGroot Jeroen; Ben Zaken Chaya; Brau-Benjamin Orit; Maroudas Alice; Bank Ruud A; Mizrahi Joe; Schalkwijk Casper G; Thorpe Suzanne R; Baynes John W; Bijlsma Johannes W J; Lafeber Floris P J G; TeKoppele Johan M
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
Arthritis and rheumatism 2002;46(1):114-23.
2001: DeGroot J; Verzijl N; Jacobs K M; Budde M; Bank R A; Bijlsma J W; TeKoppele J M; Lafeber F P
Accumulation of advanced glycation endproducts reduces chondrocyte-mediated extracellular matrix turnover in human articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(8):720-6.
2001: DeGroot J; Verzijl N; Wenting-Van Wijk M J; Bank R A; Lafeber F P; Bijlsma J W; TeKoppele J M
Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: the role of advanced glycation end products.
Arthritis and rheumatism 2001;44(11):2562-71.
2001: Verzijl N; DeGroot J; Bank R A; Bayliss M T; Bijlsma J W; Lafeber F P; Maroudas A; TeKoppele J M
Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover.
Matrix biology : journal of the International Society for Matrix Biology 2001;20(7):409-17.
2001: Verhoef C M; van Roon J A; Vianen M E; Bijlsma J W; Lafeber F P
Interleukin 10 (IL-10), not IL-4 or interferon-gamma production, correlates with progression of joint destruction in rheumatoid arthritis.
The Journal of rheumatology 2001;28(9):1960-6.
2001: DeGroot J; Verzijl N; Budde M; Bijlsma J W; Lafeber F P; TeKoppele J M
Accumulation of advanced glycation end products decreases collagen turnover by bovine chondrocytes.
Experimental cell research 2001;266(2):303-10.
2001: Marijnissen A C; Vincken K L; Viergever M A; van Roy H L; Van Roermund P M; Lafeber F P; Bijlsma J W
Ankle images digital analysis (AIDA): digital measurement of joint space width and subchondral sclerosis on standard radiographs.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(3):264-72.
2001: van Roon J A; Lafeber F P; Bijlsma J W
Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis.
Arthritis and rheumatism 2001;44(1):3-12.
2000: Verzijl N; DeGroot J; Thorpe S R; Bank R A; Shaw J N; Lyons T J; Bijlsma J W; Lafeber F P; Baynes J W; TeKoppele J M
Effect of collagen turnover on the accumulation of advanced glycation end products.
The Journal of biological chemistry 2000;275(50):39027-31.
2000: Verzijl N; DeGroot J; Oldehinkel E; Bank R A; Thorpe S R; Baynes J W; Bayliss M T; Bijlsma J W; Lafeber F P; Tekoppele J M
Age-related accumulation of Maillard reaction products in human articular cartilage collagen.
The Biochemical journal 2000;350 Pt 2():381-7.
2000: Roosendaal G; Tekoppele J M; Vianen M E; van den Berg H M; Lafeber F P; Bijlsma J W
Articular cartilage is more susceptible to blood induced damage at young than at old age.
The Journal of rheumatology 2000;27(7):1740-4.
2000: van Valburg A A; van Roermund P M; Marijnissen A C; Wenting M J; Verbout A J; Lafeber F P; Bijlsma J W
Joint distraction in treatment of osteoarthritis (II): effects on cartilage in a canine model.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2000;8(1):1-8.
1999: Lafeber F P; Beukelman C J; van den Worm E; van Roy J L; Vianen M E; van Roon J A; van Dijk H; Bijlsma J W
Apocynin, a plant-derived, cartilage-saving drug, might be useful in the treatment of rheumatoid arthritis.
Rheumatology (Oxford, England) 1999;38(11):1088-93.
1999: Verhoef C M; Van Roon J A; Vianen M E; Glaudemans C A; Lafeber F P; Bijlsma J W
Lymphocyte stimulation by CD3-CD28 enables detection of low T cell interferon-gamma and interleukin-4 production in rheumatoid arthritis.
Scandinavian journal of immunology 1999;50(4):427-32.
1999: van Valburg A A; van Roermund P M; Marijnissen A C; van Melkebeek J; Lammens J; Verbout A J; Lafeber F P; Bijlsma J W
Joint distraction in treatment of osteoarthritis: a two-year follow-up of the ankle.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1999;7(5):474-9.
1999: Wenting-Van Wijk M J; Blankenstein M A; Lafeber F P; Bijlsma J W
Relation of plasma dexamethasone to clinical response.
Clinical and experimental rheumatology 1999;17(3):305-12.
1999: Roosendaal G; TeKoppele J M; Vianen M E; van den Berg H M; Lafeber F P; Bijlsma J W
Blood-induced joint damage: a canine in vivo study.
Arthritis and rheumatism 1999;42(5):1033-9.
1999: Roosendaal G; Vianen M E; Marx J J; van den Berg H M; Lafeber F P; Bijlsma J W
Blood-induced joint damage: a human in vitro study.
Arthritis and rheumatism 1999;42(5):1025-32.
1999: DeGroot J; Verzijl N; Bank R A; Lafeber F P; Bijlsma J W; TeKoppele J M
Age-related decrease in proteoglycan synthesis of human articular chondrocytes: the role of nonenzymatic glycation.
Arthritis and rheumatism 1999;42(5):1003-9.
1999: Roosendaal G; van Rinsum A C; Vianen M E; van den Berg H M; Lafeber F P; Bijlsma J W
Haemophilic arthropathy resembles degenerative rather than inflammatory joint disease.
Histopathology 1999;34(2):144-53.
1999: Verhoef C M; van Roon J A; Vianen M E; Lafeber F P; Bijlsma J W
The immune suppressive effect of dexamethasone in rheumatoid arthritis is accompanied by upregulation of interleukin 10 and by differential changes in interferon gamma and interleukin 4 production.
Annals of the rheumatic diseases 1999;58(1):49-54.
1999: van Roermund P M; Lafeber F P
Joint distraction as treatment for ankle osteoarthritis.
Instructional course lectures 1999;48():249-54.
1998: Roosendaal G; Mauser-Bunschoten E P; De Kleijn P; Heijnen L; van den Berg H M; Van Rinsum A C; Lafeber F P; Bijlsma J W
Synovium in haemophilic arthropathy.
Haemophilia : the official journal of the World Federation of Hemophilia 1998;4(4):502-5.
1998: Verhoef C M; van Roon J A; Vianen M E; Bruijnzeel-Koomen C A; Lafeber F P; Bijlsma J W
Mutual antagonism of rheumatoid arthritis and hay fever; a role for type 1/type 2 T cell balance.
Annals of the rheumatic diseases 1998;57(5):275-80.
1998: Roosendaal G; Vianen M E; Wenting M J; van Rinsum A C; van den Berg H M; Lafeber F P; Bijlsma J W
Iron deposits and catabolic properties of synovial tissue from patients with haemophilia.
The Journal of bone and joint surgery. British volume 1998;80(3):540-5.
1998: van Roermund P M; van Valburg A A; Duivemann E; van Melkebeek J; Lafeber F P; Bijlsma J W; Verbout A J
Function of stiff joints may be restored by Ilizarov joint distraction.
Clinical orthopaedics and related research 1998;(348):220-7.
1998: van Valburg A A; van Roy H L; Lafeber F P; Bijlsma J W
Beneficial effects of intermittent fluid pressure of low physiological magnitude on cartilage and inflammation in osteoarthritis. An in vitro study.
The Journal of rheumatology 1998;25(3):515-20.
1998: Bank R A; Bayliss M T; Lafeber F P; Maroudas A; Tekoppele J M
Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage.
The Biochemical journal 1998;330 ( Pt 1)():345-51.
1997: Bank R A; Krikken M; Beekman B; Stoop R; Maroudas A; Lafeber F P; te Koppele J M
A simplified measurement of degraded collagen in tissues: application in healthy, fibrillated and osteoarthritic cartilage.
Matrix biology : journal of the International Society for Matrix Biology 1997;16(5):233-43.
1997: van Roon J A; Verhoef C M; van Roy J L; Gmelig-Meyling F H; Huber-Bruning O; Lafeber F P; Bijlsma J W
Decrease in peripheral type 1 over type 2 T cell cytokine production in patients with rheumatoid arthritis correlates with an increase in severity of disease.
Annals of the rheumatic diseases 1997;56(11):656-60.
1997: Roosendaal G; Vianen M E; van den Berg H M; Lafeber F P; Bijlsma J W
Cartilage damage as a result of hemarthrosis in a human in vitro model.
The Journal of rheumatology 1997;24(7):1350-4.
1997: Lafeber F P; van Roy H L; van der Kraan P M; van den Berg W B; Bijlsma J W
Transforming growth factor-beta predominantly stimulates phenotypically changed chondrocytes in osteoarthritic human cartilage.
The Journal of rheumatology 1997;24(3):536-42.
1997: van Valburg A A; Wenting M J; Beekman B; Te Koppele J M; Lafeber F P; Bijlsma J W
Degenerated human articular cartilage at autopsy represents preclinical osteoarthritic cartilage: comparison with clinically defined osteoarthritic cartilage.
The Journal of rheumatology 1997;24(2):358-64.
1996: Verschure P J; Marle J V; Joosten L A; Helsen M M; Lafeber F P; Berg W B
Localization of insulin-like growth factor-1 receptor in human normal and osteoarthritic cartilage in relation to proteoglycan synthesis and content.
British journal of rheumatology 1996;35(11):1044-55.
1996: van Roon J A; van Roy J L; Gmelig-Meyling F H; Lafeber F P; Bijlsma J W
Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4.
Arthritis and rheumatism 1996;39(5):829-35.
1996: van der Veen M J; Scheven B A; van Roy J L; Damen C A; Lafeber F P; Bijlsma J W
In vitro effects of methotrexate on human articular cartilage and bone-derived osteoblasts.
British journal of rheumatology 1996;35(4):342-9.
1996: van Roon J A; van Roy J L; Lafeber F P; Bijlsma J W
The stimulation of mononuclear cells from patients with rheumatoid arthritis to degrade articular cartilage is not modulated by cartilage itself.
Clinical and experimental rheumatology 1996;14(2):177-82.
1995: van Roon J A; van Roy J L; Duits A; Lafeber F P; Bijlsma J W
Proinflammatory cytokine production and cartilage damage due to rheumatoid synovial T helper-1 activation is inhibited by interleukin-4.
Annals of the rheumatic diseases 1995;54(10):836-40.
1995: Scheven B A; van der Veen M J; Damen C A; Lafeber F P; Van Rijn H J; Bijlsma J W; Duursma S A
Effects of methotrexate on human osteoblasts in vitro: modulation by 1,25-dihydroxyvitamin D3.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(6):874-80.
1994: Sauren Y M; Mieremet R H; Lafeber F P; Huber-Bruning O; Groot C G; Scherft J P
Changes in proteoglycans of ageing and osteoarthritic human articular cartilage: an electron microscopic study with polyethyleneimine.
The Anatomical record 1994;240(2):208-16.
1993: Lafeber F P; Vander Kraan P M; Huber-Bruning O; Vanden Berg W B; Bijlsma J W
Osteoarthritic human cartilage is more sensitive to transforming growth factor beta than is normal cartilage.
British journal of rheumatology 1993;32(4):281-6.
1993: Lafeber F P; Vander Kraan P M; Van Roy J L; Huber-Bruning O; Bijlsma J W
Articular cartilage explant culture; an appropriate in vitro system to compare osteoarthritic and normal human cartilage.
Connective tissue research 1993;29(4):287-99.
1992: Lafeber F; Veldhuijzen J P; Vanroy J L; Huber-Bruning O; Bijlsma J W
Intermittent hydrostatic compressive force stimulates exclusively the proteoglycan synthesis of osteoarthritic human cartilage.
British journal of rheumatology 1992;31(7):437-42.
1992: Lafeber F P; van der Kraan P M; van Roy H L; Vitters E L; Huber-Bruning O; van den Berg W B; Bijlsma J W
Local changes in proteoglycan synthesis during culture are different for normal and osteoarthritic cartilage.
The American journal of pathology 1992;140(6):1421-9.
1992: Lafeber F P; van Roy H; Wilbrink B; Huber-Bruning O; Bijlsma J W
Human osteoarthritic cartilage is synthetically more active but in culture less vital than normal cartilage.
The Journal of rheumatology 1992;19(1):123-9.

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