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Iain Bruce

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Myocardial Ischemic Preconditioning

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Dongxu He; Iain C Bruce; Yanfei Cai; Yun Chen; Xin Ma; Xiaochen Ru; Guiyang Shi; Qiang Xia; Jian Jin
Luteolin inhibits pyrogallol-induced apoptosis through the extracellular signal-regulated kinase signaling pathway.
Jia Shen; Xiao-Yin Bai; Yuan Qin; Wei-Wei Jin; Jing-Yin Zhou; Ji-Ping Zhou; Ying-Gang Yan; Qiong Wang; Iain C Bruce; Jiang-Hua Chen; Qiang Xia
Interrupted reperfusion reduces the activation of NADPH oxidase after cerebral I/R injury.
Ling-Bo Qian; Hui-Ping Wang; Ying Chen; Fang-Xia Chen; Yan-Yan Ma; Iain C Bruce; Qiang Xia
Luteolin reduces high glucose-mediated impairment of endothelium-dependent relaxation in rat aorta by reducing oxidative stress.

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All Publications

2012: Dongxu He; Iain C Bruce; Yanfei Cai; Yun Chen; Xin Ma; Xiaochen Ru; Guiyang Shi; Qiang Xia; Jian Jin
Luteolin inhibits pyrogallol-induced apoptosis through the extracellular signal-regulated kinase signaling pathway.
The FEBS journal 2012;279(10):1834-43.
2011: Jia Shen; Xiao-Yin Bai; Yuan Qin; Wei-Wei Jin; Jing-Yin Zhou; Ji-Ping Zhou; Ying-Gang Yan; Qiong Wang; Iain C Bruce; Jiang-Hua Chen; Qiang Xia
Interrupted reperfusion reduces the activation of NADPH oxidase after cerebral I/R injury.
Free radical biology & medicine 2011;50(12):1780-6.
2010: Ling-Bo Qian; Hui-Ping Wang; Ying Chen; Fang-Xia Chen; Yan-Yan Ma; Iain C Bruce; Qiang Xia
Luteolin reduces high glucose-mediated impairment of endothelium-dependent relaxation in rat aorta by reducing oxidative stress.
Pharmacological research : the official journal of the Italian Pharmacological Society 2010;61(4):281-7.
2009: Bi-hui Jin; Ling-Bo Qian; Shuai Chen; Jun Li; Hui-ping Wang; Iain C Bruce; Jun Lin; Qiang Xia
Apigenin protects endothelium-dependent relaxation of rat aorta against oxidative stress.
European journal of pharmacology 2009;616(1-3):200-5.
2009: Li-Na Sun; Jia Shen; Fang Su; Qian Wang; Yu-Jin Zhu; Xiao-E Lou; Hua-Wei Liang; Iain C Bruce; Qiang Xia
Bicyclol attenuates oxidative stress and neuronal damage following transient forebrain ischemia in mouse cortex and hippocampus.
Neuroscience letters 2009;459(2):84-7.
2008: Manli Xia; Lingbo Qian; Xinmei Zhou; Qin Gao; Iain C Bruce; Qiang Xia
Endothelium-independent relaxation and contraction of rat aorta induced by ethyl acetate extract from leaves of Morus alba (L.).
Journal of ethnopharmacology 2008;120(3):442-6.
2008: Xiao-Chen Ru; Ling-Bo Qian; Qin Gao; Yan-Fang Li; Iain C Bruce; Qiang Xia
Alcohol induces relaxation of rat thoracic aorta and mesenteric arterial bed.
Alcohol and alcoholism (Oxford, Oxfordshire) 2008;43(5):537-43.
2008: Xin Ma; Yan-fang Li; Qin Gao; Zhi-guo Ye; Xin-jiang Lu; Hui-Ping Wang; Hui-Di Jiang; Iain C Bruce; Qiang Xia
Inhibition of superoxide anion-mediated impairment of endothelium by treatment with luteolin and apigenin in rat mesenteric artery.
Life sciences 2008;83(3-4):110-7.
2008: Hua-Wei Liang; Shui-Feng Qiu; Jia Shen; Li-Na Sun; Jing-Ye Wang; Iain C Bruce; Qiang Xia
Genistein attenuates oxidative stress and neuronal damage following transient global cerebral ischemia in rat hippocampus.
Neuroscience letters 2008;438(1):116-20.
2008: Jing-ye Wang; Jia Shen; Qin Gao; Zhi-guo Ye; Shui-you Yang; Hua-wei Liang; Iain C Bruce; Ben-yan Luo; Qiang Xia
Ischemic postconditioning protects against global cerebral ischemia/reperfusion-induced injury in rats.
Stroke; a journal of cerebral circulation 2008;39(3):983-90.
2007: Qin Gao; Bo Yang; Zhi-guo Ye; Jue Wang; Iain C Bruce; Qiang Xia
Opening the calcium-activated potassium channel participates in the cardioprotective effect of puerarin.
European journal of pharmacology 2007;574(2-3):179-84.
2006: Ling-Bo Qian; Hui-Ping Wang; Wei-Ling Qiu; He Huang; Iain C Bruce; Qiang Xia
Interleukin-2 protects against endothelial dysfunction induced by high glucose levels in rats.
Vascular pharmacology 2006;45(6):374-82.
2006: Shi-zhong Zhang; Ning-fu Wang; Jian Xu; Qin Gao; Guo-hua Lin; Iain C Bruce; Qiang Xia
Kappa-opioid receptors mediate cardioprotection by remote preconditioning.
Anesthesiology 2006;105(3):550-6.
2006: Hui-Ping Wang; Qin Gao; Ru-Huan Mei; Meng-Hui Zhao; Yuan Lu; Xu-Yun Li; Iain C Bruce; Qiang Xia
Mechanisms underlying biochanin A-induced relaxation of the aorta differ between normotensive and hypertensive rats.
Clinical and experimental pharmacology & physiology 2006;33(9):802-7.
2006: Liping Wu; Fang Shen; Lin Lin; Xiong Zhang; Iain C Bruce; Qiang Xia
The neuroprotection conferred by activating the mitochondrial ATP-sensitive K+ channel is mediated by inhibiting the mitochondrial permeability transition pore.
Neuroscience letters 2006;402(1-2):184-9.
2006: Qin Gao; Hong-Yang Pan; Shuang Qiu; Yuan Lu; Iain C Bruce; Jian-Hong Luo; Qiang Xia
Atractyloside and 5-hydroxydecanoate block the protective effect of puerarin in isolated rat heart.
Life sciences 2006;79(3):217-24.
2006: Shi-Zhong Zhang; Qin Gao; Chun-Mei Cao; Iain C Bruce; Qiang Xia
Involvement of the mitochondrial calcium uniporter in cardioprotection by ischemic preconditioning.
Life sciences 2006;78(7):738-45.
2006: Li-Xia Yang; Chun-lei Jin; Zheng-Bing Zhu-Ge; Shuang Wang; Er-Qing Wei; Iain C Bruce; Zhong Chen
Unilateral low-frequency stimulation of central piriform cortex delays seizure development induced by amygdaloid kindling in rats.
Neuroscience 2006;138(4):1089-96.
2005: Qin Gao; Shi-Zhong Zhang; Chun-Mei Cao; Iain C Bruce; Qiang Xia
The mitochondrial permeability transition pore and the Ca2+-activated K+ channel contribute to the cardioprotection conferred by tumor necrosis factor-alpha.
Cytokine 2005;32(5):199-205.
2005: Bao-Ping Chen; Hong-Jiao Mao; Fang-Yan Fan; Iain C Bruce; Qiang Xia
Delayed uncoupling is related to cardioprotection induced by kappa-agonist U-50,488H in rat heart.
Scandinavian cardiovascular journal : SCJ 2005;39(6):375-82.
2005: Bao-Ping Chen; Hong-Jiao Mao; Fang-Yan Fan; Iain C Bruce; Qiang Xia
Delayed uncoupling contributes to the protective effect of heptanol against ischaemia in the rat isolated heart.
Clinical and experimental pharmacology & physiology 2005;32(8):655-62.
2005: Huidi Jiang; Qiang Xia; Xiaoxia Wang; Jianfeng Song; Iain C Bruce
Luteolin induces vasorelaxion in rat thoracic aorta via calcium and potassium channels.
Die Pharmazie 2005;60(6):444-7.
2005: Hua-Wei Liang; Qiang Xia; Iain C Bruce
Reactive oxygen species mediate the neuroprotection conferred by a mitochondrial ATP-sensitive potassium channel opener during ischemia in the rat hippocampal slice.
Brain research 2005;1042(2):169-75.
2005: Yi N Ye; William Ka-Kei Wu; Vivian Shin; Iain C Bruce; Benjamin Chun-Yu Wong; Chi-Hin Cho
Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke.
Carcinogenesis 2005;26(4):827-34.
2004: Ru Lin; Ze-wei Zhang; Qi-Xing Xiong; Chun-Mei Cao; Qiang Shu; Iain C Bruce; Qiang Xia
Pinacidil improves contractile function and intracellular calcium handling in isolated cardiac myocytes exposed to simulated cardioplegic arrest.
The Annals of thoracic surgery 2004;78(3):970-5.
2004: Ze-wei Tao; Yuan-wei Huang; Qiang Xia; Jun Fu; Zhi-hong Zhao; Xian Lu; Iain C Bruce
Early association of electrocardiogram alteration with infarct size and cardiac function after myocardial infarction.
Journal of Zhejiang University. Science 2004;5(4):494-8.
2004: Yan-qin Yu; Qiang Xia; Rong-bao Zhang; Qi-xian Shan; Iain C Bruce
Dorsal column is not involved in the mechanism of the hypotensive effect by simulating acupuncture on rat hindlimb.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;7():4741-3.
2004: S-Z Zhang; Qiang Xia; Chun-Mei Cao; Qin Gao; Iain C Bruce
The mitochondrial calcium uniporter participates in ischemia/reperfusion injury and in cardioprotection by ischemic preconditioning.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;5():3625-7.
2004: Qin Gao; Qiang Xia; Chun-Mei Cao; S-Z Zhang; Iain C Bruce
Role of the mitochondrial permeability transition pore in TNF-alpha-induced recovery of ventricular contraction and reduction of infarct size in isolated rat hearts subjected to ischemia/reperfusion.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2004;5():3622-4.
2004: Yue-Liang Shen; Ying-Ying Chen; Xun-Dong Wu; Iain C Bruce; Qiang Xia
Activation of mitochondrial ATP-sensitive potassium channels delays ischemia-induced cellular uncoupling in rat heart.
Acta pharmacologica Sinica 2004;25(1):22-8.
2003: Chun-Mei Cao; Qiang Xia; Iain C Bruce; Yue-Liang Shen; Zhi-guo Ye; Guo-hua Lin; Jun-zhu Chen; Gui-Rong Li
Influence of interleukin-2 on Ca2+ handling in rat ventricular myocytes.
Journal of molecular and cellular cardiology 2003;35(12):1491-503.
2003: Chun-Mei Cao; Qiang Xia; Iain C Bruce; Xiong Zhang; Chen Fu; Jun-zhu Chen
Interleukin-2 increases activity of sarcoplasmic reticulum Ca2+-ATPase, but decreases its sensitivity to calcium in rat cardiomyocytes.
The Journal of pharmacology and experimental therapeutics 2003;306(2):572-80.