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Michael Glocker

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Toralf Reimer; Dagmar-Ulrike Richter; Henrike Rohrmann; Johannes Stubert; Michael O Glocker; Ulrich Pecks; Bernd Gerber
Angiogenic factors and acute-phase proteins in serum samples of preeclampsia and HELLP patients: a matched-pair analysis.
Manja Wölter; Cornelia Koy; Ulrich Pecks; Werner Rath; Toralf Reimer; Claudia Röwer; Michael O Glocker
A proteome signature for intrauterine growth restriction derived from multifactorial analysis of mass spectrometry-based cord blood serum profiling.
Michael Linnebacher; Peter Lorenz; Felix Steinbeck; Hans-Jürgen Thiesen; Johannes Wollbold; Nadine Born; A Jahnke; Cornelia Koy; Tobias Latzkow; Michael O Glocker
Clonality characterization of natural epitope-specific antibodies against the tumor-related antigen topoisomerase IIa by peptide chip and proteome analysis: a pilot study with colorectal carcinoma patient samples.

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All Publications

2013: Toralf Reimer; Dagmar-Ulrike Richter; Henrike Rohrmann; Johannes Stubert; Michael O Glocker; Ulrich Pecks; Bernd Gerber
Angiogenic factors and acute-phase proteins in serum samples of preeclampsia and HELLP patients: a matched-pair analysis.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2013;26(3):263-9.
2012: Manja Wölter; Cornelia Koy; Ulrich Pecks; Werner Rath; Toralf Reimer; Claudia Röwer; Michael O Glocker
A proteome signature for intrauterine growth restriction derived from multifactorial analysis of mass spectrometry-based cord blood serum profiling.
Electrophoresis 2012;33(12):1881-93.
2012: Michael Linnebacher; Peter Lorenz; Felix Steinbeck; Hans-Jürgen Thiesen; Johannes Wollbold; Nadine Born; A Jahnke; Cornelia Koy; Tobias Latzkow; Michael O Glocker
Clonality characterization of natural epitope-specific antibodies against the tumor-related antigen topoisomerase IIa by peptide chip and proteome analysis: a pilot study with colorectal carcinoma patient samples.
Analytical and bioanalytical chemistry 2012;403(1):227-38.
2012: Ulrich Pecks; Stephanie Preschany; Werner Rath; Toralf Reimer; Claudia Röwer; Markus Schmidt; Antje Schütt; Holger Stepan; Michael O Glocker
A mass spectrometric multicenter study supports classification of preeclampsia as heterogeneous disorder.
Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 2012;31(2):278-91.
2011: Claudia Röwer; Oliver Schmitt; Hans-Jürgen Thiesen; Björn Ziems; Bernd Gerber; Cornelia Koy; Anngret Radtke; Toralf Reimer; Michael O Glocker
Toponostics of invasive ductal breast carcinoma: combination of spatial protein expression imaging and quantitative proteome signature analysis.
International journal of clinical and experimental pathology 2011;4(5):454-67.
2011: András Mádi; Gyöngyike Majai; Cornelia Koy; György Vámosi; Attila Szántó; Michael O Glocker; László Fésüs
Altered sialylation on the cell-surface proteins of dexamethasone-treated human macrophages contributes to augmented uptake of apoptotic neutrophils.
Immunology letters 2011;135(1-2):88-95.
2011: Claudia Röwer; Cornelia Koy; Michael Hecker; Toralf Reimer; Bernd Gerber; Hans-Jürgen Thiesen; Michael O Glocker
Mass spectrometric characterization of protein structure details refines the proteome signature for invasive ductal breast carcinoma.
Journal of the American Society for Mass Spectrometry 2011;22(3):440-56.
2010: Ulrich Pecks; Franka Seidenspinner; Claudia Röwer; Toralf Reimer; Werner Rath; Michael O Glocker
Multifactorial analysis of affinity-mass spectrometry data from serum protein samples: a strategy to distinguish patients with preeclampsia from matching control individuals.
Journal of the American Society for Mass Spectrometry 2010;21(10):1699-711.
2010: Stefan Mikkat; Peter Lorenz; Christian Scharf; Xinhua Yu; Michael O Glocker; Saleh M Ibrahim
MS characterization of qualitative protein polymorphisms in the spinal cords of inbred mouse strains.
Proteomics 2010;10(5):1050-62.
2010: R F El-Kased; Cornelia Koy; Peter Lorenz; Susanne Drynda; Reinhard Guthke; Z Qian; Dirk Koczan; Y Li; Jörn Kekow; Hans-Jürgen Thiesen; Michael O Glocker
Mass spectrometric and peptide chip epitope analysis on the RA33 autoantigen with sera from rheumatoid arthritis patients.
European journal of mass spectrometry (Chichester, England) 2010;16(3):443-51.
2009: Claudia Röwer; Johannes P C Vissers; Cornelia Koy; Marc Kipping; Michael Hecker; Toralf Reimer; Bernd Gerber; Hans-Jürgen Thiesen; Michael O Glocker
Towards a proteome signature for invasive ductal breast carcinoma derived from label-free nanoscale LC-MS protein expression profiling of tumorous and glandular tissue.
Analytical and bioanalytical chemistry 2009;395(8):2443-56.
2009: Mike Kienbaum; Cornelia Koy; Helen V Montgomery; Susanne Drynda; Peter Lorenz; Harald Illges; Koichi Tanaka; Jörn Kekow; Reinhard Guthke; Hans-Juergen Thiesen; Michael O Glocker
MS characterization of apheresis samples from rheumatoid arthritis patients for the improvement of immunoadsorption therapy - a pilot study.
Proteomics. Clinical applications 2009;3(7):797-809.
2009: R F El-Kased; Cornelia Koy; T Deierling; P Lorenz; Z Qian; Y Li; Hans-Jürgen Thiesen; Michael O Glocker
Mass spectrometric and peptide chip epitope mapping of rheumatoid arthritis autoantigen RA33.
European journal of mass spectrometry (Chichester, England) 2009;15(6):747-59.
2008: András Mádi; Stefan Mikkat; Cornelia Koy; Bruno Ringel; Hans-Jürgen Thiesen; Michael O Glocker
Mass spectrometric proteome analysis suggests anaerobic shift in metabolism of Dauer larvae of Caenorhabditis elegans.
Biochimica et biophysica acta 2008;1784(11):1763-70.
2008: Tomas Fiedler; Maren Mix; Uta Meyer; Stefan Mikkat; Michael O Glocker; Hubert Bahl; Ralf-Jörg Fischer
The two-component system PhoPR of Clostridium acetobutylicum is involved in phosphate-dependent gene regulation.
Journal of bacteriology 2008;190(20):6559-67.
2008: Thomas Köller; Daniel Nelson; Masanobu Nakata; Michael Kreutzer; Vincent Fischetti; Michael O Glocker; Andreas Podbielski; Bernd Kreikemeyer
PlyC, a novel bacteriophage lysin for compartment-dependent proteomics of group A streptococci.
Proteomics 2008;8(1):140-8.
2007: Bernd Kreikemeyer; Masanobu Nakata; Thomas Köller; Hendrikje Hildisch; Vassilios Kourakos; Kerstin Standar; Shigetada Kawabata; Michael O Glocker; Andreas Podbielski
The Streptococcus pyogenes serotype M49 Nra-Ralp3 transcriptional regulatory network and its control of virulence factor expression from the novel eno ralp3 epf sagA pathogenicity region.
Infection and immunity 2007;75(12):5698-710.
2007: Zsolt Sarang; András Mádi; Cornelia Koy; S Varga; Michael O Glocker; David S Ucker; Shafi M Kuchay; Athar H Chishti; Gerry Melino; László Fésüs; Zsuzsa Szondy
Tissue transglutaminase (TG2) facilitates phosphatidylserine exposure and calpain activity in calcium-induced death of erythrocytes.
Cell death and differentiation 2007;14(10):1842-4.
2006: Zhenpeng Li; Michael Kreutzer; Stefan Mikkat; Nikica Mise; Michael O Glocker; Brigitte M Pützer
Proteomic analysis of the E2F1 response in p53-negative cancer cells: new aspects in the regulation of cell survival and death.
Proteomics 2006;6(21):5735-45.
2006: J C Heitner; Cornelia Koy; Michael Kreutzer; B Gerber; Toralf Reimer; Michael O Glocker
Differentiation of HELLP patients from healthy pregnant women by proteome analysis--on the way towards a clinical marker set.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;840(1):10-9.
2006: Tino Just; Evariste Gafumbegete; Jan Gramberg; Ines Prüfer; Stefan Mikkat; Bruno Ringel; Hans Wilhelm Pau; Michael O Glocker
Differential proteome analysis of tonsils from children with chronic tonsillitis or with hyperplasia reveals disease-associated protein expression differences.
Analytical and bioanalytical chemistry 2006;384(5):1134-44.
2006: Michael O Glocker; Reinhard Guthke; Jörn Kekow; Hans-Jürgen Thiesen
Rheumatoid arthritis, a complex multifactorial disease: on the way toward individualized medicine.
Medicinal research reviews 2006;26(1):63-87.
2005: Cornelia Koy; Juliane C Heitner; Ralf Woisch; Michael Kreutzer; Pablo Serrano-Fernandez; Rüdiger Gohlke; Toralf Reimer; Michael O Glocker
Cryodetector mass spectrometry profiling of plasma samples for HELLP diagnosis: an exploratory study.
Proteomics 2005;5(12):3079-87.
2005: Steffen Möller; Eilhard Mix; Martin Blüggel; Pablo Serrano-Fernández; Dirk Koczan; Vasilis Kotsikoris; Manfred Kunz; Michael Watson; Jens Pahnke; Harald Illges; Michael Kreutzer; Stefan Mikkat; Hans-Jürgen Thiesen; Michael O Glocker; Uwe K Zettl; Saleh M Ibrahim
Collection of soluble variants of membrane proteins for transcriptomics and proteomics.
In silico biology 2005;5(3):295-311.
2004: Madhan Masilamani; Rainer Nowack; T Witte; Michael Schlesier; Klaus Warnatz; Michael O Glocker; Hans-Hartmut Peter; Harald Illges
Reduction of soluble complement receptor 2/CD21 in systemic lupus erythomatosus and Sjogren's syndrome but not juvenile arthritis.
Scandinavian journal of immunology 2004;60(6):625-30.
2004: Stefan Mikkat; Cornelia Koy; Markus Ulbrich; Bruno Ringel; Michael O Glocker
Mass spectrometric protein structure characterization reveals cause of migration differences of haptoglobin alpha chains in two-dimensional gel electrophoresis.
Proteomics 2004;4(12):3921-32.
2004: Marcus Bantscheff; Bruno Ringel; András Madi; Ralf Schnabel; Michael O Glocker; Hans-Jürgen Thiesen
Differential proteome analysis and mass spectrometric characterization of germ line development-related proteins of Caenorhabditis elegans.
Proteomics 2004;4(8):2283-95.
2004: András Mádi; Raimund Hoffrogge; Bernadett Blaskó; Michael O Glocker; László Fésüs
Amine donor protein substrates for transglutaminase activity in Caenorhabditis elegans.
Biochemical and biophysical research communications 2004;315(4):1064-9.
2004: P Christ; S Rutzinger; W Seidel; S Uchaikin; F Prö; Cornelia Koy; Michael O Glocker
High detection sensitivity achieved with cryogenic detectors in combination with matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry.
European journal of mass spectrometry (Chichester, England) 2004;10(4):469-76.
2004: Susanne Drynda; Bruno Ringel; Monika Kekow; Cornelia Kühne; Andreas Drynda; Michael O Glocker; Hans-Jürgen Thiesen; Jörn Kekow
Proteome analysis reveals disease-associated marker proteins to differentiate RA patients from other inflammatory joint diseases with the potential to monitor anti-TNFalpha therapy.
Pathology, research and practice 2004;200(2):165-71.
2004: Cornelia Koy; Michael O Glocker; Martin Resch; Koichi Tanaka
Primary structure details of haptoglobin alpha chain proteins from human plasma samples are resolved by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight multiple-stage tandem mass spectrometry sequencing.
European journal of mass spectrometry (Chichester, England) 2004;10(3):393-9.
2003: Peter Lorenz; Marcus Bantscheff; Saleh M Ibrahim; Hans-Jürgen Thiesen; Michael O Glocker
Proteome analysis of diseased joints from mice suffering from collagen-induced arthritis.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003;41(12):1622-32.
2003: Manfred Kunz; Steffen Moeller; Dirk Koczan; Peter Lorenz; Roland H Wenger; Michael O Glocker; Hans-Jürgen Thiesen; Gerd Gross; Saleh M Ibrahim
Mechanisms of hypoxic gene regulation of angiogenesis factor Cyr61 in melanoma cells.
The Journal of biological chemistry 2003;278(46):45651-60.
2003: Madhan Masilamani; Daniela Kassahn; Stefan Mikkat; Michael O Glocker; Harald Illges
B cell activation leads to shedding of complement receptor type II (CR2/CD21).
European journal of immunology 2003;33(9):2391-7.
2003: András Mádi; Stefan Mikkat; Bruno Ringel; Markus Ulbrich; Hans-Jürgen Thiesen; Michael O Glocker
Mass spectrometric proteome analysis for profiling temperature-dependent changes of protein expression in wild-type Caenorhabditis elegans.
Proteomics 2003;3(8):1526-34.
2003: Cornelia Koy; Stefan Mikkat; Emmanuel Raptakis; Chris Sutton; Martin Resch; Koichi Tanaka; Michael O Glocker
Matrix-assisted laser desorption/ionization- quadrupole ion trap-time of flight mass spectrometry sequencing resolves structures of unidentified peptides obtained by in-gel tryptic digestion of haptoglobin derivatives from human plasma proteomes.
Proteomics 2003;3(6):851-8.
2003: András Mádi; Stefan Mikkat; Bruno Ringel; Hans-Jürgen Thiesen; Michael O Glocker
Profiling stage-dependent changes of protein expression in Caenorhabditis elegans by mass spectrometric proteome analysis leads to the identification of stage-specific marker proteins.
Electrophoresis 2003;24(11):1809-17.
2002: H Peter Happersberger; Cynthia Cowgill; Michael O Glocker
Structural characterization of monomeric folding intermediates of recombinant human macrophage-colony stimulating factor beta (rhM-CSFbeta) by chemical trapping, chromatographic separation and mass spectrometric peptide mapping.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;782(1-2):393-404.
2002: Andrea Sinz; Marcus Bantscheff; Stefan Mikkat; Bruno Ringel; Susanne Drynda; Jörn Kekow; Hans-Jürgen Thiesen; Michael O Glocker
Mass spectrometric proteome analyses of synovial fluids and plasmas from patients suffering from rheumatoid arthritis and comparison to reactive arthritis or osteoarthritis.
Electrophoresis 2002;23(19):3445-56.
2001: Andreas Bock; Marcus Bantscheff; Anne-Laure Perraud; Karsten Rippe; V Weiss; Michael O Glocker; Roy Gross
Rational design and molecular characterization of a chimaeric response regulator protein.
Journal of molecular biology 2001;310(2):283-90.
2000: Marcus Bantscheff; Anne-Laure Perraud; Andreas Bock; Karsten Rippe; V Weiss; Michael O Glocker; Roy Gross
Structure-function relationships in the Bvg and Evg two-component phosphorelay systems.
International journal of medical microbiology : IJMM 2000;290(4-5):317-23.
2000: S Barbirz; Ursula Jakob; Michael O Glocker
Mass spectrometry unravels disulfide bond formation as the mechanism that activates a molecular chaperone.
The Journal of biological chemistry 2000;275(25):18759-66.
2000: Anne-Laure Perraud; Karsten Rippe; Marcus Bantscheff; Michael O Glocker; M Lucassen; K Jung; Walter Sebald; V Weiss; Roy Gross
Dimerization of signalling modules of the EvgAS and BvgAS phosphorelay systems.
Biochimica et biophysica acta 2000;1478(2):341-54.
2000: HP Happersberger; Marcus Bantscheff; S Barbirz; Michael O Glocker
Multiple and subsequent MALDI-MS on-target chemical reactions for the characterization of disulfide bonds and primary structures of proteins.
Methods in molecular biology (Clifton, N.J.) 2000;146():167-84.
1999: Marcus Bantscheff; V Weiss; Michael O Glocker
Identification of linker regions and domain borders of the transcription activator protein NtrC from Escherichia coli by limited proteolysis, in-gel digestion, and mass spectrometry.
Biochemistry 1999;38(34):11012-20.
1998: HP Happersberger; Michael Przybylski; Michael O Glocker
Selective bridging of bis-cysteinyl residues by arsonous acid derivatives as an approach to the characterization of protein tertiary structures and folding pathways by mass spectrometry.
Analytical biochemistry 1998;264(2):237-50.
1998: M Kalkum; Michael Przybylski; Michael O Glocker
Structure characterization of functional histidine residues and carbethoxylated derivatives in peptides and proteins by mass spectrometry.
Bioconjugate chemistry 1998;9(2):226-35.
1998: HP Happersberger; J Stapleton; C Cowgill; Michael O Glocker
Characterization of the folding pathway of recombinant human macrophage-colony stimulating-factor beta (rhM-CSF beta) by bis-cysteinyl modification and mass spectrometry.
Proteins 1998;Suppl 2():50-62.
1997: C Spiess; HP Happersberger; Michael O Glocker; E Spiess; Karsten Rippe; Michael Ehrmann
Biochemical characterization and mass spectrometric disulfide bond mapping of periplasmic alpha-amylase MalS of Escherichia coli.
The Journal of biological chemistry 1997;272(35):22125-33.
1996: Michael O Glocker; M Kalkum; R Yamamoto; J Schreurs
Selective biochemical modification of functional residues in recombinant human macrophage colony-stimulating factor beta (rhM-CSF beta): identification by mass spectrometry.
Biochemistry 1996;35(46):14625-33.
1996: Michael O Glocker; SH Bauer; J Kast; J Volz; Michael Przybylski
Characterization of specific noncovalent protein complexes by UV matrix-assisted laser desorption ionization mass spectrometry.
Journal of mass spectrometry : JMS 1996;31(11):1221-7.
1996: Michael Przybylski; Michael O Glocker; U Nestel; V Schnaible; M Blüggel; Kay Diederichs; Jürgen Weckesser; M Schad; A Schmid; Wolfram Welte; R Benz
X-ray crystallographic and mass spectrometric structure determination and functional characterization of succinylated porin from Rhodobacter capsulatus: implications for ion selectivity and single-channel conductance.
Protein science : a publication of the Protein Society 1996;5(8):1477-89.
1996: M Schuhmacher; Michael O Glocker; M Wunderlin; Michael Przybylski
Direct isolation of proteins from sodium dodecyl sulfate-polyacrylamide gel electrophoresis and analysis by electrospray-ionization mass spectrometry.
Electrophoresis 1996;17(5):848-54.
1995: Michael Przybylski; J Kast; Michael O Glocker; E Dürr; Hans Rudolf Bosshard; S Nock; M Sprinzl
Mass spectrometric approaches to molecular characterization of protein-nucleic acid interactions.
Toxicology letters 1995;82-83():567-75.
1994: Michael O Glocker; C Borchers; W Fiedler; D Suckau; Michael Przybylski
Molecular characterization of surface topology in protein tertiary structures by amino-acylation and mass spectrometric peptide mapping.
Bioconjugate chemistry 1994;5(6):583-90.
1994: Michael O Glocker; B Arbogast; R Milley; C Cowgill; Max L Deinzer
Disulfide linkages in the in vitro refolded intermediates of recombinant human macrophage-colony-stimulating factor: analysis of the sulfhydryl alkylation of free cysteine residues by fast-atom bombardment mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):5868-72.
1993: Michael O Glocker; B Arbogast; J Schreurs; Max L Deinzer
Assignment of the inter- and intramolecular disulfide linkages in recombinant human macrophage colony stimulating factor using fast atom bombardment mass spectrometry.
Biochemistry 1993;32(2):482-8.