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Denis Sereno

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Feten Abbassi; Thierry Foulon; Elodie Gazanion; Pierre Nicolas; Bruno Oury; Christophe Piesse; Zahid Raja; Denis Sereno; Ali Ladram
Antibacterial and leishmanicidal activities of temporin-SHd, a 17-residue long membrane-damaging peptide.
K Aït-Oudhia; J P Dedet; E Gazanion; Bruno Oury; F Pratlong; Denis Sereno; L Lachaud
In vitro susceptibility to antimonials and amphotericin B of Leishmania infantum strains isolated from dogs in a region lacking drug selection pressure.
Jorian Prudhomme; Nil Rahola; Denis Sereno; Anne-Laure Bañuls; A Boumezzough; S Guernaoui; Filiz Gunay; Fouad Ouanaimi; Bulent Alten
Wing size and shape variation of Phlebotomus papatasi (Diptera: Psychodidae) populations from the south and north slopes of the Atlas Mountains in Morocco.

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All Publications

2013: Feten Abbassi; Thierry Foulon; Elodie Gazanion; Pierre Nicolas; Bruno Oury; Christophe Piesse; Zahid Raja; Denis Sereno; Ali Ladram
Antibacterial and leishmanicidal activities of temporin-SHd, a 17-residue long membrane-damaging peptide.
Biochimie 2013;95(2):388-99.
2012: K Aït-Oudhia; J P Dedet; E Gazanion; Bruno Oury; F Pratlong; Denis Sereno; L Lachaud
In vitro susceptibility to antimonials and amphotericin B of Leishmania infantum strains isolated from dogs in a region lacking drug selection pressure.
Veterinary parasitology 2012;187(3-4):386-93.
2012: Jorian Prudhomme; Nil Rahola; Denis Sereno; Anne-Laure Bañuls; A Boumezzough; S Guernaoui; Filiz Gunay; Fouad Ouanaimi; Bulent Alten
Wing size and shape variation of Phlebotomus papatasi (Diptera: Psychodidae) populations from the south and north slopes of the Atlas Mountains in Morocco.
Journal of vector ecology : journal of the Society for Vector Ecology 2012;37(1):137-47.
2012: Elodie Gazanion; Veronika Seblova; Baptiste Vergnes; Petr Volf; Jan Votypka; Déborah Garcia; Denis Sereno
Leishmania infantum nicotinamidase is required for late-stage development in its natural sand fly vector, Phlebotomus perniciosus.
International journal for parasitology 2012;42(4):323-7.
2011: Khatima Aït-Oudhia; Elodie Gazanion; Bruno Oury; Baptiste Vergnes; Denis Sereno
Leishmania antimony resistance: what we know what we can learn from the field.
Parasitology research 2011;109(5):1225-32.
2011: E Gazanion; C Gérard; Jean-François Guichou; G Labesse; Ali Ouaissi; Denis Sereno; M Seveno; Ricardo Silvestre; Anabela Cordeiro-da-Silva; D Garcia; Baptiste Vergnes
The Leishmania nicotinamidase is essential for NAD+ production and parasite proliferation.
Molecular microbiology 2011;82(1):21-38.
2011: S Guernaoui; B Boumezzough; D Fontenille; D Garcia; Denis Sereno
Preliminary study on the galectin molecular diversity in Moroccoan Phlebotomus papatasi sandfly population.
Journal of vector borne diseases 2011;48(2):67-71.
2011: Khatima Ait-Oudhia; Elodie Gazanion; Bruno Oury; Baptiste Vergnes; Denis Sereno
The fitness of antimony-resistant Leishmania parasites: lessons from the field.
Trends in parasitology 2011;27(4):141-2.
2011: S Guernaoui; D Garcia; E Gazanion; Y Ouhdouch; A Boumezzough; B Pesson; D Fontenille; Denis Sereno
Bacterial flora as indicated by PCR-temperature gradient gel electrophoresis (TGGE) of 16S rDNA gene fragments from isolated guts of phlebotomine sand flies (Diptera: Psychodidae).
Journal of vector ecology : journal of the Society for Vector Ecology 2011;36 Suppl 1():S144-7.
2011: Natthanej Luplertlop; Pornapat Surasombatpattana; Sirilaksana Patramool; Emilie Dumas; Ladawan Wasinpiyamongkol; Laure Saune; Rodolphe Hamel; Eric Bernard; Denis Sereno; Frédéric Thomas; David Piquemal; Hans Yssel; Laurence Briant; Dorothée Missé
Induction of a peptide with activity against a broad spectrum of pathogens in the Aedes aegypti salivary gland, following Infection with Dengue Virus.
PLoS pathogens 2011;7(1):e1001252.
2011: Elodie Gazanion; Baptiste Vergnes; Marie Seveno; Deborah Garcia; Bruno Oury; Khatima Ait-Oudhia; Ali Ouaissi; Denis Sereno
In vitro activity of nicotinamide/antileishmanial drug combinations.
Parasitology international 2011;60(1):19-24.
2010: S Guernaoui; K Ramaoui; N Rahola; C Barnabe; Denis Sereno; A Boumezzough
Malformations of the genitalia in male Phlebotomus papatasi (Scopoli) (Diptera: Psychodidae).
Journal of vector ecology : journal of the Society for Vector Ecology 2010;35(1):13-9.
2010: Lucia Acebey; Valérie Jullian; Denis Sereno; Séverine Chevalley; Yannick Estevez; Claude Moulis; Stephan Beck; Alex Valentin; Alberto Gimenez; Michel Sauvain
Anti-leishmanial lindenane sesquiterpenes from Hedyosmum angustifolium.
Planta medica 2010;76(4):365-8.
2010: Rosa Milagros Corrales; Denis Sereno; Françoise Mathieu-Daudé
Deciphering the Leishmania exoproteome: what we know and what we can learn.
FEMS immunology and medical microbiology 2010;58(1):27-38.
2010: Rosa M Corrales; Françoise Mathieu-Daudé; Déborah Garcia; Simone F Brenière; Denis Sereno
An experimental approach for the identification of conserved secreted proteins in trypanosomatids.
Journal of biomedicine & biotechnology 2010;2010():752698.
2008: Joana Tavares; Ali Ouaissi; Nuno Santarém; Denis Sereno; Baptiste Vergnes; Paula Sampaio; Anabela Cordeiro-da-Silva
The Leishmania infantum cytosolic SIR2-related protein 1 (LiSIR2RP1) is an NAD+ -dependent deacetylase and ADP-ribosyltransferase.
The Biochemical journal 2008;415(3):377-86.
2008: Feten Abbassi; Bruno Oury; Thierry Blasco; Denis Sereno; Gérard Bolbach; Pierre Nicolas; Khaled Hani; Mohamed Amiche; Ali Ladram
Isolation, characterization and molecular cloning of new temporins from the skin of the North African ranid Pelophylax saharica.
Peptides 2008;29(9):1526-33.
2008: M Hide; A S Ritleng; J P Brizard; A Monte-Allegre; Denis Sereno
Leishmania infantum: tuning digitonin fractionation for comparative proteomic of the mitochondrial protein content.
Parasitology research 2008;103(4):989-92.
2008: Paul-André Genest; Anass Haimeur; Danielle Légaré; Denis Sereno; Gaétan Roy; Nadine Messier; Barbara Papadopoulou; Marc Ouellette
A protein of the leucine-rich repeats (LRRs) superfamily is implicated in antimony resistance in Leishmania infantum amastigotes.
Molecular and biochemical parasitology 2008;158(1):95-9.
2007: Françoise Mathieu-Daudé; Marie-France Bosseno; Edwin Garzon; Joël Lelièvre; Denis Sereno; Ali Ouaissi; Simone Frédérique Brenière
Sequence diversity and differential expression of Tc52 immuno-regulatory protein in Trypanosoma cruzi: potential implications in the biological variability of strains.
Parasitology research 2007;101(5):1355-63.
2007: Ricardo Silvestre; Anabela Cordeiro-da-Silva; Nuno Santarém; Baptiste Vergnes; Denis Sereno; Ali Ouaissi
SIR2-deficient Leishmania infantum induces a defined IFN-gamma/IL-10 pattern that correlates with protection.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):3161-70.
2007: Monte-Alegre Adriano; Baptiste Vergnes; Joel Poncet; Françoise Mathieu-Daude; Anabela Cordeiro Da Silva; Ali Ouaissi; Denis Sereno
Proof of interaction between Leishmania SIR2RP1 deacetylase and chaperone HSP83.
Parasitology research 2007;100(4):811-8.
2007: Denis Sereno; Anabela Cordeiro-da-Silva; Françoise Mathieu-Daude; Ali Ouaissi
Advances and perspectives in Leishmania cell based drug-screening procedures.
Parasitology international 2007;56(1):3-7.
2006: Denis Sereno; Baptiste Vergnes; Françoise Mathieu-Daude; Anabela Cordeiro-da-Silva; Ali Ouaissi
Looking for putative functions of the Leishmania cytosolic SIR2 deacetylase.
Parasitology research 2006;100(1):1-9.
2006: Ricardo Silvestre; Anabela Cordeiro-da-Silva; Joana Tavares; Denis Sereno; Ali Ouaissi
Leishmania cytosolic silent information regulatory protein 2 deacetylase induces murine B-cell differentiation and in vivo production of specific antibodies.
Immunology 2006;119(4):529-40.
2006: Philippe Holzmuller; Mallorie Hide; Denis Sereno; Jean-Loup Lemesre
Leishmania infantum amastigotes resistant to nitric oxide cytotoxicity: Impact on in vitro parasite developmental cycle and metabolic enzyme activities.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2006;6(3):187-97.
2006: Adriano Monte-Alegre; Ali Ouaissi; Denis Sereno
Leishmania amastigotes as targets for drug screening.
Kinetoplastid biology and disease 2006;5():6.
2005: Baptiste Vergnes; Denis Sereno; Joana Tavares; Anabela Cordeiro-da-Silva; Laurent Vanhille; Niloufar Madjidian-Sereno; Delphine Depoix; Adriano Monte-Alegre; Ali Ouaissi
Targeted disruption of cytosolic SIR2 deacetylase discloses its essential role in Leishmania survival and proliferation.
Gene 2005;363():85-96.
2005: Margarida Borges; Anabela Cordeiro-da-Silva; Baptiste Vergnes; Denis Sereno; Ali Ouaissi
Conversion of Trypanosoma cruzi Tc52 released factor to a protein inducing apoptosis.
Tissue & cell 2005;37(6):469-78.
2005: Philippe Holzmuller; Denis Sereno; Jean-Loup Lemesre
Lower nitric oxide susceptibility of trivalent antimony-resistant amastigotes of Leishmania infantum.
Antimicrobial agents and chemotherapy 2005;49(10):4406-9.
2005: E Garzon; F Genna; Marie-France Bosseno; J Simony-La Fontaine; M Radal; Denis Sereno; Françoise Mathieu-Daude; Ali Ouaissi; Simone Frédérique Brenière
Differential infectivity and immunopathology in murine experimental infections by two natural clones belonging to the Trypanosoma cruzi I lineage.
Parasitology 2005;131(Pt 1):109-19.
2005: Baptiste Vergnes; Laurent Vanhille; Ali Ouaissi; Denis Sereno
Stage-specific antileishmanial activity of an inhibitor of SIR2 histone deacetylase.
Acta tropica 2005;94(2):107-15.
2005: Denis Sereno; A Monte Alegre; Ricardo Silvestre; Baptiste Vergnes; Ali Ouaissi
In vitro antileishmanial activity of nicotinamide.
Antimicrobial agents and chemotherapy 2005;49(2):808-12.
2004: Diana Villarreal; Christian Barnabé; Denis Sereno; Michel Tibayrenc
Lack of correlation between in vitro susceptibility to Benznidazole and phylogenetic diversity of Trypanosoma cruzi, the agent of Chagas disease.
Experimental parasitology 2004;108(1-2):24-31.
2003: Margarida Borges; Anabela Cordeiro Da Silva; Denis Sereno; Ali Ouaissi
Peptide-based analysis of the amino acid sequence important to the immunoregulatory function of Trypanosoma cruzi Tc52 virulence factor.
Immunology 2003;109(1):147-55.
2003: Anabela Cordeiro-da-Silva; Luís Cardoso; Natália Araújo; Helena Castro; Ana M Tomás; Manuela Rodrigues; M Cabral; Baptiste Vergnes; Denis Sereno; Ali Ouaissi
Identification of antibodies to Leishmania silent information regulatory 2 (SIR2) protein homologue during canine natural infections: pathological implications.
Immunology letters 2003;86(2):155-62.
2002: Baptiste Vergnes; Denis Sereno; Niloufar Madjidian-Sereno; Jean-Loup Lemesre; Ali Ouaissi
Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death.
Gene 2002;296(1-2):139-50.
2002: Philippe Holzmuller; Denis Sereno; Mireille Cavaleyra; Isabelle Mangot; Sylvie Daulouede; Philippe Vincendeau; Jean-Loup Lemesre
Nitric oxide-mediated proteasome-dependent oligonucleosomal DNA fragmentation in Leishmania amazonensis amastigotes.
Infection and immunity 2002;70(7):3727-35.
2002: Nathalie Boucher; Ying Wu; Carole Dumas; Marthe Dube; Denis Sereno; Marie Breton; Barbara Papadopoulou
A common mechanism of stage-regulated gene expression in Leishmania mediated by a conserved 3'-untranslated region element.
The Journal of biological chemistry 2002;277(22):19511-20.
2002: Ali Ouaissi; Mehdi Ouaissi; Denis Sereno
Glutathione S-transferases and related proteins from pathogenic human parasites behave as immunomodulatory factors.
Immunology letters 2002;81(3):159-64.
2001: Denis Sereno; Eliane Guilvard; S Maquaire; Mireille Cavaleyra; Philippe Holzmuller; Ali Ouaissi; Jean-Loup Lemesre
Experimental studies on the evolution of antimony-resistant phenotype during the in vitro life cycle of Leishmania infantum: implications for the spread of chemoresistance in endemic areas.
Acta tropica 2001;80(3):195-205.
2001: Denis Sereno; Philippe Holzmuller; I Mangot; G Cuny; Ali Ouaissi; Jean-Loup Lemesre
Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes.
Antimicrobial agents and chemotherapy 2001;45(7):2064-9.
2001: Philip Agnew; Philippe Holzmuller; Yannis Michalakis; Denis Sereno; Jean-Loup Lemesre; François Renaud
In vitro growth of Leishmania amazonensis promastigotes resistant to pentamidine is dependent on interactions among strains.
Antimicrobial agents and chemotherapy 2001;45(6):1928-9.
2001: Denis Sereno; Gaétan Roy; Jean-Loup Lemesre; Barbara Papadopoulou; Marc Ouellette
DNA transformation of Leishmania infantum axenic amastigotes and their use in drug screening.
Antimicrobial agents and chemotherapy 2001;45(4):1168-73.
2000: Ying Wu; Youssef El Fakhry; Denis Sereno; S Tamar; Barbara Papadopoulou
A new developmentally regulated gene family in Leishmania amastigotes encoding a homolog of amastin surface proteins.
Molecular and biochemical parasitology 2000;110(2):345-57.
2000: Gaétan Roy; Carole Dumas; Denis Sereno; Ying Wu; A K Singh; M J Tremblay; Marc Ouellette; Martin Olivier; Barbara Papadopoulou
Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models.
Molecular and biochemical parasitology 2000;110(2):195-206.
2000: Denis Sereno; Philippe Holzmuller; Jean-Loup Lemesre
Efficacy of second line drugs on antimonyl-resistant amastigotes of Leishmania infantum.
Acta tropica 2000;74(1):25-31.
1999: K Zemzoumi; Eliane Guilvard; Denis Sereno; A Preto; M Benlemlih; Anabela Cordeiro Da Silva; Jean-Loup Lemesre; Ali Ouaissi
Cloning of a Leishmania major gene encoding for an antigen with extensive homology to ribosomal protein S3a.
Gene 1999;240(1):57-65.
1999: P Cibrelus; Eric Précigout; Denis Sereno; Bernard Carcy; Jean-Loup Lemesre; André Gorenflot
Secreted antigens of the amastigote and promastigote forms of Leishmania infantum inducing a humoral response in humans and dogs.
Parasite (Paris, France) 1999;6(2):121-9.
1999: T Merlen; Denis Sereno; N Brajon; F Rostand; Jean-Loup Lemesre
Leishmania spp: completely defined medium without serum and macromolecules (CDM/LP) for the continuous in vitro cultivation of infective promastigote forms.
The American journal of tropical medicine and hygiene 1999;60(1):41-50.
1998: Denis Sereno; Mireille Cavaleyra; K Zemzoumi; S Maquaire; Ali Ouaissi; Jean-Loup Lemesre
Axenically grown amastigotes of Leishmania infantum used as an in vitro model to investigate the pentavalent antimony mode of action.
Antimicrobial agents and chemotherapy 1998;42(12):3097-102.
1998: K Zemzoumi; Denis Sereno; C François; Eliane Guilvard; Jean-Loup Lemesre; Ali Ouaissi
Leishmania major: cell type dependent distribution of a 43 kDa antigen related to silent information regulatory-2 protein family.
Biology of the cell / under the auspices of the European Cell Biology Organization 1998;90(3):239-45.
1997: Denis Sereno; P Michon; N Brajon; Jean-Loup Lemesre
Phenotypic characterization of Leishmania mexicana pentamidine-resistant promastigotes. Modulation of the resistance during in-vitro developmental life cycle.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1997;320(12):981-7.
1997: Denis Sereno; Jean-Loup Lemesre
In vitro life cycle of pentamidine-resistant amastigotes: stability of the chemoresistant phenotypes is dependent on the level of resistance induced.
Antimicrobial agents and chemotherapy 1997;41(9):1898-903.
1997: Jean-Loup Lemesre; Denis Sereno; Sylvie Daulouède; Bernard Veyret; N Brajon; Philippe Vincendeau
Leishmania spp.: nitric oxide-mediated metabolic inhibition of promastigote and axenically grown amastigote forms.
Experimental parasitology 1997;86(1):58-68.
1997: Denis Sereno; Jean-Loup Lemesre
Axenically cultured amastigote forms as an in vitro model for investigation of antileishmanial agents.
Antimicrobial agents and chemotherapy 1997;41(5):972-6.
1997: Denis Sereno; Jean-Loup Lemesre
Use of an enzymatic micromethod to quantify amastigote stage of Leishmania amazonensis in vitro.
Parasitology research 1997;83(4):401-3.