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Ana Silva

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Chemicals & Drugs

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Tânia Martins; Ana P Silva; António F Ambrósio; Thomas Burgoyne; Clare Futter; John Greenwood; Natalie Hudson; Bridget-Ann Kenny; Patric Turowski
Methamphetamine-induced nitric oxide promotes vesicular transport in blood-brain barrier endothelial cells.
João O Malva; Fabienne Agasse; S Baptista; Raquel Ferreira; J Valero; Sara Xapelli; Ana P Silva
Multifaces of neuropeptide Y in the brain--neuroprotection, neurogenesis and neuroinflammation.
Joana Gonçalves; João O Malva; Mikkel V Olesen; Sofia Baptista; Carlos Fontes-Ribeiro; David Woldbye; Ana P Silva
Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment.

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All Publications

2013: Tânia Martins; Ana P Silva; António F Ambrósio; Thomas Burgoyne; Clare Futter; John Greenwood; Natalie Hudson; Bridget-Ann Kenny; Patric Turowski
Methamphetamine-induced nitric oxide promotes vesicular transport in blood-brain barrier endothelial cells.
Neuropharmacology 2013;65():74-82.
2012: João O Malva; Fabienne Agasse; S Baptista; Raquel Ferreira; J Valero; Sara Xapelli; Ana P Silva
Multifaces of neuropeptide Y in the brain--neuroprotection, neurogenesis and neuroinflammation.
Neuropeptides 2012;46(6):299-308.
2012: Joana Gonçalves; João O Malva; Mikkel V Olesen; Sofia Baptista; Carlos Fontes-Ribeiro; David Woldbye; Ana P Silva
Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment.
Journal of neurochemistry 2012;123(6):1041-53.
2012: Joana Gonçalves; João O Malva; Carlos F Ribeiro; Ana P Silva
Protective role of neuropeptide Y Y₂ receptors in cell death and microglial response following methamphetamine injury.
The European journal of neuroscience 2012;36(9):3173-83.
2012: Clarissa Schitine; Ana P Silva; Sara Xapelli; Laura Sardà-Arroyo; Fabienne Agasse; Fernando G de Mello; Ricardo Augusto de Melo Reis; João O Malva
Ampakine CX546 increases proliferation and neuronal differentiation in subventricular zone stem/progenitor cell cultures.
The European journal of neuroscience 2012;35(11):1672-83.
2012: Sofia Baptista; Ana Rita Bento; Liliana Bernardino; Carlos Fontes-Ribeiro; Joana Gonçalves; Andrea Lobo; João O Malva; Fabienne Agasse; Teresa Summavielle; Ana P Silva
Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures.
Neuropharmacology 2012;62(7):2413-23.
2012: Raquel Ferreira; Fabienne Agasse; Stéphanie Cochaud; Luísa Cortes; Tiago Santos; Ana P Silva; Sara Xapelli; João O Malva
Neuropeptide Y inhibits interleukin-1 beta-induced microglia motility.
Journal of neurochemistry 2012;120(1):93-105.
2011: Tânia Martins; Nuno Milhazes; Oscar Quintela; Carlos F Ribeiro; António F Ambrósio; Sofia Baptista; Fernanda Borges; Joana Gonçalves; Ermelindo C Leal; Elena Lendoiro; Manuel López-Rivadulla; Ana P Silva
Methamphetamine transiently increases the blood-brain barrier permeability in the hippocampus: role of tight junction proteins and matrix metalloproteinase-9.
Brain research 2011;1411():28-40.
2011: Ana Rita Bento; Sofia Baptista; João O Malva; Ana P Silva; Fabienne Agasse
Methamphetamine exerts toxic effects on subventricular zone stem/progenitor cells and inhibits neuronal differentiation.
Rejuvenation research 2011;14(2):205-14.
2011: C A Fontes-Ribeiro; Elsa Marques; Frederico Pereira; Ana P Silva; Tice Macedo
May exercise prevent addiction?
Current neuropharmacology 2011;9(1):45-8.
2010: Ana P Silva; Tânia Martins; Sofia Baptista; Joana Gonçalves; Fabienne Agasse; João O Malva
Brain injury associated with widely abused amphetamines: neuroinflammation, neurogenesis and blood-brain barrier.
Current drug abuse reviews 2010;3(4):239-54.
2010: Joana Gonçalves; Sofia Baptista; Tânia Martins; Nuno Milhazes; Fernanda Borges; Carlos F Ribeiro; João O Malva; Ana P Silva
Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin.
The European journal of neuroscience 2010;31(2):315-26.
2008: Elsa Marques; Filipa Vasconcelos; Marta R Rolo; Frederico Pereira; Ana P Silva; Tice Macedo; Carlos F Ribeiro
Influence of chronic exercise on the amphetamine-induced dopamine release and neurodegeneration in the striatum of the rat.
Annals of the New York Academy of Sciences 2008;1139():222-31.
2008: Joana Gonçalves; Tânia Martins; Raquel Ferreira; Nuno Milhazes; Fernanda Borges; Carlos F Ribeiro; João O Malva; Tice Macedo; Ana P Silva
Methamphetamine-induced early increase of IL-6 and TNF-alpha mRNA expression in the mouse brain.
Annals of the New York Academy of Sciences 2008;1139():103-11.
2008: Sara Xapelli; Liliana Bernardino; Raquel Ferreira; S Grade; Ana P Silva; J R Salgado; Cláudia Cavadas; Eric Grouzmann; Frantz Rom Poulsen; B Jakobsen; Catarina R Oliveira; Jens Zimmer; João O Malva
Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia.
The European journal of neuroscience 2008;27(8):2089-102.
2007: Ana P Silva; Joana Lourenço; Sara Xapelli; Raquel Ferreira; Heidi Kristiansen; David Woldbye; Catarina R Oliveira; João O Malva
Protein kinase C activity blocks neuropeptide Y-mediated inhibition of glutamate release and contributes to excitability of the hippocampus in status epilepticus.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(3):671-81.
2007: Sara Xapelli; Ana P Silva; Raquel Ferreira; João O Malva
Neuropeptide Y can rescue neurons from cell death following the application of an excitotoxic insult with kainate in rat organotypic hippocampal slice cultures.
Peptides 2007;28(2):288-94.
2006: Sara Xapelli; Fabienne Agasse; Raquel Ferreira; Ana P Silva; João O Malva
Neuropeptide Y as an endogenous antiepileptic, neuroprotective and pro-neurogenic peptide.
Recent patents on CNS drug discovery 2006;1(3):315-24.
2005: Ana P Silva; Sara Xapelli; Eric Grouzmann; Cláudia Cavadas
The putative neuroprotective role of neuropeptide Y in the central nervous system.
Current drug targets. CNS and neurological disorders 2005;4(4):331-47.
2005: Liliana Bernardino; Sara Xapelli; Ana P Silva; Birthe Jakobsen; Frantz Rom Poulsen; Catarina R Oliveira; Annamaria Vezzani; João O Malva; Jens Zimmer
Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(29):6734-44.
2005: Ana P Silva; Jocelyne E Kaufmann; Cécile Vivancos; Stanislav Fakan; Cláudia Cavadas; Phillip Shaw; Hans R Brunner; Ulrich Vischer; Eric Grouzmann
Neuropeptide Y expression, localization and cellular transducing effects in HUVEC.
Biology of the cell / under the auspices of the European Cell Biology Organization 2005;97(6):457-67.
2005: Ana P Silva; Sara Xapelli; Paulo S Pinheiro; Raquel Ferreira; Joana Lourenço; Armando J Cristóvão; Eric Grouzmann; Cláudia Cavadas; Catarina R Oliveira; João O Malva
Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats.
Journal of neurochemistry 2005;93(1):163-70.
2003: Ana P Silva; Cláudia Cavadas; Bénédicte Baïsse-Agushi; Olivier Spertini; Hans R Brunner; Eric Grouzmann
NPY, NPY receptors, and DPP IV activity are modulated by LPS, TNF-alpha and IFN-gamma in HUVEC.
Regulatory peptides 2003;116(1-3):71-9.
2003: João O Malva; Ana P Silva; Rodrigo A Cunha
Presynaptic modulation controlling neuronal excitability and epileptogenesis: role of kainate, adenosine and neuropeptide Y receptors.
Neurochemical research 2003;28(10):1501-15.
2003: A Cristina Rego; Nuno M Monteiro; Ana P Silva; Joana Gil; João O Malva; Catarina R Oliveira
Mitochondrial apoptotic cell death and moderate superoxide generation upon selective activation of non-desensitizing AMPA receptors in hippocampal cultures.
Journal of neurochemistry 2003;86(4):792-804.
2003: Ana P Silva; Paulo S Pinheiro; Arsélio P Carvalho; Caetana M Carvalho; Birthe Jakobsen; Jens Zimmer; João O Malva
Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1118-20.
2003: Ana P Silva; Arsélio P Carvalho; Caetana M Carvalho; João O Malva
Functional interaction between neuropeptide Y receptors and modulation of calcium channels in the rat hippocampus.
Neuropharmacology 2003;44(2):282-92.
2003: Paulo S Pinheiro; Ricardo Jorge Rodrigues; Ana P Silva; Rodrigo A Cunha; Catarina R Oliveira; João O Malva
Solubilization and immunological identification of presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in the rat hippocampus.
Neuroscience letters 2003;336(2):97-100.
2002: Ana P Silva; Cláudia Cavadas; Eric Grouzmann
Neuropeptide Y and its receptors as potential therapeutic drug targets.
Clinica chimica acta; international journal of clinical chemistry 2002;326(1-2):3-25.
2002: Cláudia Cavadas; Ana P Silva; Maria Dulce Cotrim; C A Fontes Ribeiro; Hans R Brunner; Eric Grouzmann
Differential secretion of catecholamine and neuropeptide Y in response to KCl from mice chromaffin cells.
Annals of the New York Academy of Sciences 2002;971():335-7.
2001: Cláudia Cavadas; Ana P Silva; François Mosimann; Maria Dulce Cotrim; C A Fontes Ribeiro; Hans R Brunner; Eric Grouzmann
NPY regulates catecholamine secretion from human adrenal chromaffin cells.
The Journal of clinical endocrinology and metabolism 2001;86(12):5956-63.
2001: Ana P Silva; Arsélio P Carvalho; Caetana M Carvalho; João O Malva
Modulation of intracellular calcium changes and glutamate release by neuropeptide Y1 and Y2 receptors in the rat hippocampus: differential effects in CA1, CA3 and dentate gyrus.
Journal of neurochemistry 2001;79(2):286-96.
2001: Ana P Silva; João O Malva; António F Ambrósio; A J Salgado; Arsélio P Carvalho; Caetana M Carvalho
Role of kainate receptor activation and desensitization on the [Ca(2+)](i) changes in cultured rat hippocampal neurons.
Journal of neuroscience research 2001;65(5):378-86.
2001: António F Ambrósio; Ana P Silva; João O Malva; Patrício Soares-da-Silva; Arsélio P Carvalho; Caetana M Carvalho
Inhibition of glutamate release by BIA 2-093 and BIA 2-024, two novel derivatives of carbamazepine, due to blockade of sodium but not calcium channels.
Biochemical pharmacology 2001;61(10):1271-5.
2000: António F Ambrósio; Ana P Silva; Inês M Araújo; João O Malva; Patrício Soares-da-Silva; Arsélio P Carvalho; Caetana M Carvalho
Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024.
European journal of pharmacology 2000;406(2):191-201.
2000: António F Ambrósio; Ana P Silva; João O Malva; José F Mesquita; Arsélio P Carvalho; Caetana M Carvalho
Role of desensitization of AMPA receptors on the neuronal viability and on the [Ca2+]i changes in cultured rat hippocampal neurons.
The European journal of neuroscience 2000;12(6):2021-31.
1999: António F Ambrósio; Ana P Silva; João O Malva; Patrício Soares-da-Silva; Arsélio P Carvalho; Caetana M Carvalho
Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists.
Neuropharmacology 1999;38(9):1349-59.