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Fuad Ziyadeh

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Mona P Nasrallah; Fuad N Ziyadeh
Overview of the physiology and pathophysiology of leptin with special emphasis on its role in the kidney.
Bassem Y Tanios; Fuad N Ziyadeh
Emerging therapies for diabetic nephropathy patients: beyond blockade of the Renin-Angiotensin system.
Fuad N Ziyadeh; Fadel Jaber; Salam Koussa; Naji S Mallat; Samir Mallat; Ali Abdulnabi Mohamed; Khaled M Musallam; Ali T Taher
Glomerular hyperfiltration and proteinuria in transfusion-independent patients with β-thalassemia intermedia.

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All Publications

2013: Mona P Nasrallah; Fuad N Ziyadeh
Overview of the physiology and pathophysiology of leptin with special emphasis on its role in the kidney.
Seminars in nephrology 2013;33(1):54-65.
2012: Bassem Y Tanios; Fuad N Ziyadeh
Emerging therapies for diabetic nephropathy patients: beyond blockade of the Renin-Angiotensin system.
Nephron extra 2012;2(1):278-82.
2012: Fuad N Ziyadeh; Fadel Jaber; Salam Koussa; Naji S Mallat; Samir Mallat; Ali Abdulnabi Mohamed; Khaled M Musallam; Ali T Taher
Glomerular hyperfiltration and proteinuria in transfusion-independent patients with β-thalassemia intermedia.
Nephron. Clinical practice 2012;121(3-4):c136-43.
2012: Miran A Jaffa; Firas Kobeissy; Fuad N Ziyadeh; Moustafa Al Hariri; Hussein Chalhoub; Assaad Eid; Ayad A Jaffa
Global renal gene expression profiling analysis in B2-kinin receptor null mice: impact of diabetes.
PloS one 2012;7(9):e44714.
2011: Charbel C Khoury; Fuad N Ziyadeh
Angiogenic factors.
Contributions to nephrology 2011;170():83-92.
2010: Hussein H Karnib; Ali G Gharavi; Georges Aftimos; ziyad mahfoud; Reem Saad; Elias Gemayel; Badiaa Masri; Shafika Assaad; KAMAL BADR; Fuad N Ziyadeh
A 5-year survey of biopsy proven kidney diseases in Lebanon: significant variation in prevalence of primary glomerular diseases by age, population structure and consanguinity.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(12):3962-9.
2010: Hussein H Karnib; Fuad N Ziyadeh
The cardiorenal syndrome in diabetes mellitus.
Diabetes research and clinical practice 2010;89(3):201-8.
2008: Sheldon Chen; Fuad N Ziyadeh
Vascular endothelial growth factor and diabetic nephropathy.
Current diabetes reports 2008;8(6):470-6.
2008: Fuad N Ziyadeh
Different roles for TGF-beta and VEGF in the pathogenesis of the cardinal features of diabetic nephropathy.
Diabetes research and clinical practice 2008;82 Suppl 1():S38-41.
2008: Hussein H Karnib; Fuad N Ziyadeh
Steroid treatment of drug-induced acute interstitial nephritis.
Kidney international 2008;74(10):1360; author reply 1360-1.
2008: Michael J Choi; Fuad N Ziyadeh
The utility of the transtubular potassium gradient in the evaluation of hyperkalemia.
Journal of the American Society of Nephrology : JASN 2008;19(3):424-6.
2008: Fuad N Ziyadeh; Gunter Wolf
Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy.
Current diabetes reviews 2008;4(1):39-45.
2007: Amy Wang; Fuad N Ziyadeh; Eun Young Lee; Petr E Pyagay; Sun Hee Sung; Steven A Sheardown; Nicholas J Laping; Sheldon Chen
Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria.
American journal of physiology. Renal physiology 2007;293(5):F1657-65.
2007: Marie Merheb; Rose T Daher; Mona Nasrallah; Ramzi Sabra; Fuad N Ziyadeh; Kassem A Barada
Taurine intestinal absorption and renal excretion test in diabetic patients: a pilot study.
Diabetes care 2007;30(10):2652-4.
2007: Gunter Wolf; Fuad N Ziyadeh
Cellular and molecular mechanisms of proteinuria in diabetic nephropathy.
Nephron. Physiology 2007;106(2):p26-31.
2006: Sun Hee Sung; Fuad N Ziyadeh; Amy Wang; Petr E Pyagay; Yashpal S Kanwar; Sheldon Chen
Blockade of vascular endothelial growth factor signaling ameliorates diabetic albuminuria in mice.
Journal of the American Society of Nephrology : JASN 2006;17(11):3093-104.
2006: Margo P Cohen; Fuad N Ziyadeh; Sheldon Chen
Amadori-modified glycated serum proteins and accelerated atherosclerosis in diabetes: pathogenic and therapeutic implications.
The Journal of laboratory and clinical medicine 2006;147(5):211-9.
2006: Gunter Wolf; Fuad N Ziyadeh
Leptin and renal fibrosis.
Contributions to nephrology 2006;151():175-83.
2005: Kathryn G Ewens; Roberta Ann George; Kumar Sharma; Fuad N Ziyadeh; Richard S Spielman
Assessment of 115 candidate genes for diabetic nephropathy by transmission/disequilibrium test.
Diabetes 2005;54(11):3305-18.
2005: Margo P Cohen; Sheldon Chen; Fuad N Ziyadeh; Elizabeth Shea; Elizabeth Hud; Gregory T Lautenslager; Clyde W Shearman
Evidence linking glycated albumin to altered glomerular nephrin and VEGF expression, proteinuria, and diabetic nephropathy.
Kidney international 2005;68(4):1554-61.
2005: Sheldon Chen; Joseph S Lee; M Carmen Iglesias-de la Cruz; Amy Wang; Adriana Izquierdo-Lahuerta; Nisha K Gandhi; Farhad R Danesh; Gunter Wolf; Fuad N Ziyadeh
Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005;20(7):1320-8.
2005: Gunter Wolf; Sheldon Chen; Fuad N Ziyadeh
From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy.
Diabetes 2005;54(6):1626-34.
2004: Sheldon Chen; Yuki Kasama; Joseph S Lee; Bun Jim; Maria Marin; Fuad N Ziyadeh
Podocyte-derived vascular endothelial growth factor mediates the stimulation of alpha3(IV) collagen production by transforming growth factor-beta1 in mouse podocytes.
Diabetes 2004;53(11):2939-49.
2004: Gunter Wolf; Regine Schroeder; Fuad N Ziyadeh; Rolf A K Stahl
Albumin up-regulates the type II transforming growth factor-beta receptor in cultured proximal tubular cells.
Kidney international 2004;66(5):1849-58.
2004: Sheldon Chen; Brenda B Hoffman; Joseph S Lee; Yuki Kasama; Bun Jim; Jeffrey B Kopp; Fuad N Ziyadeh
Cultured tubule cells from TGF-beta1 null mice exhibit impaired hypertrophy and fibronectin expression in high glucose.
Kidney international 2004;65(4):1191-204.
2004: Fuad N Ziyadeh
Mediators of diabetic renal disease: the case for tgf-Beta as the major mediator.
Journal of the American Society of Nephrology : JASN 2004;15 Suppl 1():S55-7.
2003: Sheldon Chen; Bun Jim; Fuad N Ziyadeh
Diabetic nephropathy and transforming growth factor-beta: transforming our view of glomerulosclerosis and fibrosis build-up.
Seminars in nephrology 2003;23(6):532-43.
2003: Fuad N Ziyadeh; Gunter Wolf
Why should an angiogenic factor modulate tubular structure in diabetic nephropathy? Some answers, more questions.
Kidney international 2003;64(2):758-9.
2003: Fuad N Ziyadeh; Kumar Sharma
Overview: combating diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 2003;14(5):1355-7.
2003: Sheldon Chen; M Carmen Iglesias-de la Cruz; Bun Jim; Soon Won Hong; Motohide Isono; Fuad N Ziyadeh
Reversibility of established diabetic glomerulopathy by anti-TGF-beta antibodies in db/db mice.
Biochemical and biophysical research communications 2003;300(1):16-22.
2002: Motohide Isono; Sheldon Chen; Soon Won Hong; M Carmen Iglesias-de la Cruz; Fuad N Ziyadeh
Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-beta-induced fibronectin in mesangial cells.
Biochemical and biophysical research communications 2002;296(5):1356-65.
2002: M Carmen Iglesias-de la Cruz; Fuad N Ziyadeh; Motohide Isono; Martine Kouahou; Dong Cheol Han; Raghu Kalluri; Peter Mundel; Sheldon Chen
Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes.
Kidney international 2002;62(3):901-13.
2002: Michael Zeisberg; Mark B Ericksen; Yuki Hamano; Eric G Neilson; Fuad N Ziyadeh; Raghu Kalluri
Differential expression of type IV collagen isoforms in rat glomerular endothelial and mesangial cells.
Biochemical and biophysical research communications 2002;295(2):401-7.
2002: Margo P Cohen; Fuad N Ziyadeh; Soon Won Hong; Clyde W Shearman; Elizabeth Hud; Gregory T Lautenslager; M Carmen Iglesias-de la Cruz; Sheldon Chen
Inhibiting albumin glycation in vivo ameliorates glomerular overexpression of TGF-beta1.
Kidney international 2002;61(6):2025-32.
2002: Frank Strutz; Michael Zeisberg; Fuad N Ziyadeh; Chang-Qing Yang; Raghu Kalluri; Gerhard A Müller; Eric G Neilson
Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation.
Kidney international 2002;61(5):1714-28.
2002: Nazifa Banu; Miklós Mózes; Jeffrey B Kopp; Fuad N Ziyadeh; Catherine M Meyers
Regulation of inducible class II MHC, costimulatory molecules, and cytokine expression in TGF-beta1 knockout renal epithelial cells: effect of exogenous TGF-beta1.
Experimental nephrology 2002;10(5-6):320-31.
2002: Gunter Wolf; Sheldon Chen; Dong Cheol Han; Fuad N Ziyadeh
Leptin and renal disease.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2002;39(1):1-11.
2001: Sixue Chen; Soon Won Hong; M Carmen Iglesias-de la Cruz; Motohide Isono; A Casaretto; Fuad N Ziyadeh
The key role of the transforming growth factor-beta system in the pathogenesis of diabetic nephropathy.
Renal failure 2001;23(3-4):471-81.
2001: Soon Won Hong; Motohide Isono; Sixue Chen; M Carmen Iglesias-de la Cruz; Dong Cheol Han; Fuad N Ziyadeh
Increased glomerular and tubular expression of transforming growth factor-beta1, its type II receptor, and activation of the Smad signaling pathway in the db/db mouse.
The American journal of pathology 2001;158(5):1653-63.
2001: Dong Cheol Han; Motohide Isono; Sixue Chen; A Casaretto; Soon Won Hong; Gunter Wolf; Fuad N Ziyadeh
Leptin stimulates type I collagen production in db/db mesangial cells: glucose uptake and TGF-beta type II receptor expression.
Kidney international 2001;59(4):1315-23.
2001: Sixue Chen; Margo P Cohen; Gregory T Lautenslager; Clyde W Shearman; Fuad N Ziyadeh
Glycated albumin stimulates TGF-beta 1 production and protein kinase C activity in glomerular endothelial cells.
Kidney international 2001;59(2):673-81.
2001: Gunter Wolf; T Hannken; Regine Schroeder; Gunther Zahner; Fuad N Ziyadeh; Rolf A K Stahl
Antioxidant treatment induces transcription and expression of transforming growth factor beta in cultured renal proximal tubular cells.
FEBS letters 2001;488(3):154-9.
2001: S Chen; G Wolf; Fuad N Ziyadeh
The renin-angiotensin system in diabetic nephropathy.
Contributions to nephrology 2001;(135):212-21.
2001: M Carmen Iglesias-de la Cruz; P Ruiz-Torres; J Alcamí; L Díez-Marqués; R Ortega-Velázquez; Sixue Chen; Manuel Rodríguez-Puyol; Fuad N Ziyadeh; Diego Rodríguez-Puyol
Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cells.
Kidney international 2001;59(1):87-95.
2000: Motohide Isono; M C Cruz; Sixue Chen; Soon Won Hong; Fuad N Ziyadeh
Extracellular signal-regulated kinase mediates stimulation of TGF-beta1 and matrix by high glucose in mesangial cells.
Journal of the American Society of Nephrology : JASN 2000;11(12):2222-30.
2000: S Chen; Margo P Cohen; Fuad N Ziyadeh
Amadori-glycated albumin in diabetic nephropathy: pathophysiologic connections.
Kidney international. Supplement 2000;77():S40-4.
2000: Fuad N Ziyadeh; Brenda B Hoffman; Dong Cheol Han; M Carmen Iglesias-de la Cruz; Soon Won Hong; Motohide Isono; Sixue Chen; Tracy A McGowan; Kumar Sharma
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(14):8015-20.
2000: Margo P Cohen; N Masson; Elizabeth Hud; Fuad N Ziyadeh; Dong Cheol Han; RS Clements
Inhibiting albumin glycation ameliorates diabetic nephropathy in the db/db mouse.
Experimental nephrology 2000;8(3):135-43.
2000: Motohide Isono; András Mogyorósi; Dong Cheol Han; Brenda B Hoffman; Fuad N Ziyadeh
Stimulation of TGF-beta type II receptor by high glucose in mouse mesangial cells and in diabetic kidney.
American journal of physiology. Renal physiology 2000;278(5):F830-8.
2000: Dong Cheol Han; Brenda B Hoffman; Soon Won Hong; J Guo; Fuad N Ziyadeh
Therapy with antisense TGF-beta1 oligodeoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice.
American journal of physiology. Renal physiology 2000;278(4):F628-34.
2000: Nicholas J Laping; Barbara A Olson; T Ho; Fuad N Ziyadeh; CR Albrightson
Hepatocyte growth factor: a regulator of extracellular matrix genes in mouse mesangial cells.
Biochemical pharmacology 2000;59(7):847-53.
1999: Gunter Wolf; U Wenzel; Fuad N Ziyadeh; Rolf A K Stahl
Angiotensin converting-enzyme inhibitor treatment reduces glomerular p16INK4 and p27Kip1 expression in diabetic BBdp rats.
Diabetologia 1999;42(12):1425-32.
1999: András Mogyorósi; Fuad N Ziyadeh
GLUT1 and TGF-beta: the link between hyperglycaemia and diabetic nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1999;14(12):2827-9.
1999: Kumar Sharma; B O Eltayeb; Tracy A McGowan; Stephen R Dunn; B Alzahabi; R Rohde; Fuad N Ziyadeh; E J Lewis
Captopril-induced reduction of serum levels of transforming growth factor-beta1 correlates with long-term renoprotection in insulin-dependent diabetic patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1999;34(5):818-23.
1999: Dong Cheol Han; Motohide Isono; Brenda B Hoffman; Fuad N Ziyadeh
High glucose stimulates proliferation and collagen type I synthesis in renal cortical fibroblasts: mediation by autocrine activation of TGF-beta.
Journal of the American Society of Nephrology : JASN 1999;10(9):1891-9.
1999: Gunter Wolf; A Hamann; D C Han; Udo Helmchen; Friedrich Thaiss; Fuad N Ziyadeh; Rolf A K Stahl
Leptin stimulates proliferation and TGF-beta expression in renal glomerular endothelial cells: potential role in glomerulosclerosis [seecomments].
Kidney international 1999;56(3):860-72.
1999: Gunter Wolf; Fuad N Ziyadeh
Molecular mechanisms of diabetic renal hypertrophy.
Kidney international 1999;56(2):393-405.
1999: Gunter Wolf; Fuad N Ziyadeh; Rolf A K Stahl
Angiotensin II stimulates expression of transforming growth factor beta receptor type II in cultured mouse proximal tubular cells.
Journal of molecular medicine (Berlin, Germany) 1999;77(7):556-64.
1999: Gunter Wolf; R Kalluri; Fuad N Ziyadeh; E G Neilson; Rolf A K Stahl
Angiotensin II induces alpha3(IV) collagen expression in cultured murine proximal tubular cells.
Proceedings of the Association of American Physicians 1999;111(4):357-64.
1999: András Mogyorósi; Fuad N Ziyadeh
What is the role of decorin in diabetic kidney disease?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1999;14(5):1078-81.
1999: Margo P Cohen; Fuad N Ziyadeh; Gregory T Lautenslager; JA Cohen; Clyde W Shearman
Glycated albumin stimulation of PKC-beta activity is linked to increased collagen IV in mesangial cells.
The American journal of physiology 1999;276(5 Pt 2):F684-90.
1999: Dong Cheol Han; Fuad N Ziyadeh
Favorable treatment outcome with neutralizing anti-transforming growth factor beta antibodies in experimental diabetic kidney disease.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 1999;19 Suppl 2():S234-7.
1998: A Mogyorosi; Fuad N Ziyadeh
Increased decorin mRNA in diabetic mouse kidney and in mesangial and tubular cells cultured in high glucose.
The American journal of physiology 1998;275(5 Pt 2):F827-32.
1998: Brenda B Hoffman; Kumar Sharma; Y Zhu; Fuad N Ziyadeh
Transcriptional activation of transforming growth factor-beta1 in mesangial cell culture by high glucose concentration.
Kidney international 1998;54(4):1107-16.
1998: Margo P Cohen; Kumar Sharma; J Guo; B O Eltayeb; Fuad N Ziyadeh
The renal TGF-beta system in the db/db mouse model of diabetic nephropathy.
Experimental nephrology 1998;6(3):226-33.
1998: Gunter Wolf; Regine Schroeder; Friedrich Thaiss; Fuad N Ziyadeh; Udo Helmchen; Rolf A K Stahl
Glomerular expression of p27Kip1 in diabetic db/db mouse: role of hyperglycemia.
Kidney international 1998;53(4):869-79.
1998: Fuad N Ziyadeh; Dong Cheol Han; JA Cohen; J Guo; Margo P Cohen
Glycated albumin stimulates fibronectin gene expression in glomerular mesangial cells: involvement of the transforming growth factor-beta system.
Kidney international 1998;53(3):631-8.
1998: Nicholas J Laping; Barbara A Olson; R E DeWolf; CR Albrightson; TA Fredrickson; C King; M Chirivella; Fuad N Ziyadeh; Ponnal Nambi
Activation of glomerular mesangial cells by hepatocyte growth factor through tyrosine kinase and protein kinase C.
Biochemical pharmacology 1998;55(2):227-34.
1997: Gunter Wolf; Regine Schroeder; Fuad N Ziyadeh; Friedrich Thaiss; Gunther Zahner; Rolf A K Stahl
High glucose stimulates expression of p27Kip1 in cultured mouse mesangial cells: relationship to hypertrophy.
The American journal of physiology 1997;273(3 Pt 2):F348-56.
1997: G Wolf; Fuad N Ziyadeh
Renal tubular hypertrophy induced by angiotensin II.
Seminars in nephrology 1997;17(5):448-54.
1997: Fuad N Ziyadeh; Dong Cheol Han
Involvement of transforming growth factor-beta and its receptors in the pathogenesis of diabetic nephrology.
Kidney international. Supplement 1997;60():S7-11.
1997: Gunter Wolf; Fuad N Ziyadeh; Friedrich Thaiss; J Tomaszewski; R J Caron; Ulrich Wenzel; Gunther Zahner; Udo Helmchen; Rolf A K Stahl
Angiotensin II stimulates expression of the chemokine RANTES in rat glomerular endothelial cells. Role of the angiotensin type 2 receptor.
The Journal of clinical investigation 1997;100(5):1047-58.
1997: Fuad N Ziyadeh; Margo P Cohen; J Guo; Y Jin
RAGE mRNA expression in the diabetic mouse kidney.
Molecular and cellular biochemistry 1997;170(1-2):147-52.
1997: Kumar Sharma; Fuad N Ziyadeh; B Alzahabi; Tracy A McGowan; S Kapoor; BR Kurnik; P B Kurnik; LS Weisberg
Increased renal production of transforming growth factor-beta1 in patients with type II diabetes.
Diabetes 1997;46(5):854-9.
1997: Gunter Wolf; Fuad N Ziyadeh; Regine Schroeder; Rolf A K Stahl
Angiotensin II inhibits inducible nitric oxide synthase in tubular MCT cells by a posttranscriptional mechanism.
Journal of the American Society of Nephrology : JASN 1997;8(4):551-7.
1997: Kumar Sharma; Fuad N Ziyadeh
Biochemical events and cytokine interactions linking glucose metabolism to the development of diabetic nephropathy.
Seminars in nephrology 1997;17(2):80-92.
1997: Rudolf de Châtel; András Mogyorósi; Fuad N Ziyadeh
[Current issues in the diagnosis and therapy of diabetic nephropathy].
Orvosi hetilap 1997;138(4):187-93.
1997: Fuad N Ziyadeh; András Mogyorósi; R Kalluri
Early and advanced non-enzymatic glycation products in the pathogenesis of diabetic kidney disease.
Experimental nephrology 1997;5(1):2-9.
1997: Gunter Wolf; Fuad N Ziyadeh
The role of angiotensin II in diabetic nephropathy: emphasis on nonhemodynamic mechanisms.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1997;29(1):153-63.
1996: Gunter Wolf; Gunther Zahner; Fuad N Ziyadeh; Rolf A K Stahl
Cyclosporin A induces transcription of transforming growth factor beta in a cultured murine proximal tubular cell line.
Experimental nephrology 1996;4(5):304-8.
1996: Margo P Cohen; R S Clements; E Hud; J A Cohen; Fuad N Ziyadeh
Evolution of renal function abnormalities in the db/db mouse that parallels the development of human diabetic nephropathy.
Experimental nephrology 1996;4(3):166-71.
1996: Fuad N Ziyadeh
Significance of tubulointerstitial changes in diabetic renal disease.
Kidney international. Supplement 1996;54():S10-3.
1996: Gunter Wolf; Fuad N Ziyadeh; Gunther Zahner; Rolf A K Stahl
Angiotensin II is mitogenic for cultured rat glomerular endothelial cells.
Hypertension 1996;27(4):897-905.
1996: K Sharma; Y Jin; J Guo; Fuad N Ziyadeh
Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice.
Diabetes 1996;45(4):522-30.
1996: Margo P Cohen; Fuad N Ziyadeh
Role of Amadori-modified nonenzymatically glycated serum proteins in the pathogenesis of diabetic nephropathy.
Journal of the American Society of Nephrology : JASN 1996;7(2):183-90.
1995: Gunter Wolf; Fuad N Ziyadeh; Gunther Zahner; Rolf A K Stahl
Angiotensin II-stimulated expression of transforming growth factor beta in renal proximal tubular cells: attenuation after stable transfection with the c-mas oncogene.
Kidney international 1995;48(6):1818-27.
1995: Margo P Cohen; E Hud; V Y Wu; Fuad N Ziyadeh
Albumin modified by Amadori glucose adducts activates mesangial cell type IV collagen gene transcription.
Molecular and cellular biochemistry 1995;151(1):61-7.
1995: Fuad N Ziyadeh; P Fumo; C H Rodenberger; G S Kuncio; Eric G Neilson
Role of protein kinase C and cyclic AMP/protein kinase A in high glucose-stimulated transcriptional activation of collagen alpha 1 (IV) in glomerular mesangial cells.
Journal of diabetes and its complications 1995;9(4):255-61.
1995: Fuad N Ziyadeh; K Sharma
Role of transforming growth factor-beta in diabetic glomerulosclerosis and renal hypertrophy.
Kidney international. Supplement 1995;51():S34-6.
1995: Gunter Wolf; Fuad N Ziyadeh; Rolf A K Stahl
Atrial natriuretic peptide stimulates the expression of transforming growth factor-beta in cultured murine mesangial cells: relationship to suppression of proliferation.
Journal of the American Society of Nephrology : JASN 1995;6(2):224-33.
1995: G Baffy; K Sharma; W Shi; Fuad N Ziyadeh; JR Williamson
Growth arrest of a murine mesangial cell line by transforming growth factor beta 1 is associated with inhibition of mitogen-induced Ca2+ mobilization.
Biochemical and biophysical research communications 1995;210(2):378-83.
1995: Gunter Wolf; Fuad N Ziyadeh; Udo Helmchen; Gunther Zahner; Regine Schroeder; Rolf A K Stahl
ANG II is a mitogen for a murine cell line isolated from medullary thick ascending limb of Henle's loop.
The American journal of physiology 1995;268(5 Pt 2):F940-7.
1995: Margo P Cohen; K Sharma; Y Jin; E Hud; V Y Wu; J Tomaszewski; Fuad N Ziyadeh
Prevention of diabetic nephropathy in db/db mice with glycated albumin antagonists. A novel treatment strategy.
The Journal of clinical investigation 1995;95(5):2338-45.
1995: Margo P Cohen; E Hud; V Y Wu; Fuad N Ziyadeh
Glycated albumin modified by Amadori adducts modulates aortic endothelial cell biology.
Molecular and cellular biochemistry 1995;143(1):73-9.
1995: K Sharma; Theodore M Danoff; A DePiero; Fuad N Ziyadeh
Enhanced expression of inducible nitric oxide synthase in murine macrophages and glomerular mesangial cells by elevated glucose levels: possible mediation via protein kinase C.
Biochemical and biophysical research communications 1995;207(1):80-8.
1995: Fuad N Ziyadeh
Mediators of hyperglycemia and the pathogenesis of matrix accumulation in diabetic renal disease.
Mineral and electrolyte metabolism 1995;21(4-5):292-302.
1994: K Sharma; Fuad N Ziyadeh
Renal hypertrophy is associated with upregulation of TGF-beta 1 gene expression in diabetic BB rat and NOD mouse.
The American journal of physiology 1994;267(6 Pt 2):F1094-01.
1994: P Fumo; G S Kuncio; Fuad N Ziyadeh
PKC and high glucose stimulate collagen alpha 1 (IV) transcriptional activity in a reporter mesangial cell line.
The American journal of physiology 1994;267(4 Pt 2):F632-8.
1994: A J Bleyer; P Fumo; E R Snipes; Stanley Goldfarb; D A Simmons; Fuad N Ziyadeh
Polyol pathway mediates high glucose-induced collagen synthesis in proximal tubule.
Kidney international 1994;45(3):659-66.
1994: Fuad N Ziyadeh
Role of transforming growth factor beta in diabetic nephropathy.
Experimental nephrology 1994;2(2):137.
1994: Margo P Cohen; Fuad N Ziyadeh
Amadori glucose adducts modulate mesangial cell growth and collagen gene expression.
Kidney international 1994;45(2):475-84.
1994: Fuad N Ziyadeh; K Sharma; M Ericksen; G Wolf
Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta.
The Journal of clinical investigation 1994;93(2):536-42.
1993: Fuad N Ziyadeh; Margo P Cohen
Effects of glycated albumin on mesangial cells: evidence for a role in diabetic nephropathy.
Molecular and cellular biochemistry 1993;125(1):19-25.
1993: Fuad N Ziyadeh
Renal tubular basement membrane and collagen type IV in diabetes mellitus.
Kidney international 1993;43(1):114-20.
1993: K Sharma; Fuad N Ziyadeh
The transforming growth factor-beta system and the kidney.
Seminars in nephrology 1993;13(1):116-28.
1992: G Wolf; K Sharma; Y Chen; M Ericksen; Fuad N Ziyadeh
High glucose-induced proliferation in mesangial cells is reversed by autocrine TGF-beta.
Kidney international 1992;42(3):647-56.
1992: M V Rocco; Eric G Neilson; JR Hoyer; Fuad N Ziyadeh
Attenuated expression of epithelial cell adhesion molecules in murine polycystic kidney disease.
The American journal of physiology 1992;262(4 Pt 2):F679-86.
1992: Fuad N Ziyadeh; J W Mills; A Kleinzeller
Hypotonicity and cell volume regulation in shark rectal gland: role of organic osmolytes and F-actin.
The American journal of physiology 1992;262(3 Pt 2):F468-79.
1992: B L Blazer-Yost; M Watanabe; T P Haverty; Fuad N Ziyadeh
Role of insulin and IGF1 receptors in proliferation of cultured renal proximal tubule cells.
Biochimica et biophysica acta 1992;1133(3):329-35.
1992: M V Rocco; Y Chen; Stanley Goldfarb; Fuad N Ziyadeh
Elevated glucose stimulates TGF-beta gene expression and bioactivity in proximal tubule.
Kidney international 1992;41(1):107-14.
1991: Fuad N Ziyadeh; D A Simmons; E R Snipes; Stanley Goldfarb
Effect of myo-inositol on cell proliferation and collagen transcription and secretion in proximal tubule cells cultured in elevated glucose.
Journal of the American Society of Nephrology : JASN 1991;1(11):1220-9.
1991: G Wolf; Eric G Neilson; Stanley Goldfarb; Fuad N Ziyadeh
The influence of glucose concentration on angiotensin II-induced hypertrophy of proximal tubular cells in culture.
Biochemical and biophysical research communications 1991;176(2):902-9.
1991: Stanley Goldfarb; Fuad N Ziyadeh; E F Kern; D A Simmons
Effects of polyol-pathway inhibition and dietary myo-inositol on glomerular hemodynamic function in experimental diabetes mellitus in rats.
Diabetes 1991;40(4):465-71.
1991: Fuad N Ziyadeh; Stanley Goldfarb
The renal tubulointerstitium in diabetes mellitus.
Kidney international 1991;39(3):464-75.
1990: Fuad N Ziyadeh; E R Snipes; M Watanabe; R J Alvarez; Stanley Goldfarb; T P Haverty
High glucose induces cell hypertrophy and stimulates collagen gene transcription in proximal tubule.
The American journal of physiology 1990;259(4 Pt 2):F704-14.
1990: A Kleinzeller; G W Booz; J W Mills; Fuad N Ziyadeh
pCMBS-induced swelling of dogfish (Squalus acanthias) rectal gland cells: role of the Na+,K(+)-ATPase and the cytoskeleton.
Biochimica et biophysica acta 1990;1025(1):21-31.
1989: G M Feldman; Fuad N Ziyadeh; J W Mills; G W Booz; A Kleinzeller
Propionate induces cell swelling and K+ accumulation in shark rectal gland.
The American journal of physiology 1989;257(2 Pt 1):C377-84.
1988: Fuad N Ziyadeh; Z S Agus
Benzodiazepines inhibit transport-related oxygen consumption in thick ascending limb.
The American journal of physiology 1988;255(3 Pt 1):C385-92.
1988: Fuad N Ziyadeh; G M Feldman; G W Booz; A Kleinzeller
Taurine and cell volume maintenance in the shark rectal gland: cellular fluxes and kinetics.
Biochimica et biophysica acta 1988;943(1):43-52.
1988: Fuad N Ziyadeh; E Kelepouris; Z S Agus
Benzodiazepines stimulate sodium ion transport in frog skin epithelium.
Biochimica et biophysica acta 1988;940(1):93-8.
1988: Fuad N Ziyadeh; Z S Agus
Role of calcium in chloride-secreting epithelia.
Mineral and electrolyte metabolism 1988;14(1):78-85.
1987: Fuad N Ziyadeh; E Kelepouris; Z S Agus
Thiazides stimulate calcium absorption in urinary bladder of winter flounder.
Biochimica et biophysica acta 1987;897(1):52-6.
1986: Fuad N Ziyadeh; E Kelepouris; Z S Agus
Relationships between calcium and chloride transport in frog skin glands.
The American journal of physiology 1986;251(4 Pt 2):F647-54.
1986: Z S Agus; Fuad N Ziyadeh; E Kelepouris
Mechanisms of calcium transport in the thick ascending limb of the loop of Henle.
Advances in experimental medicine and biology 1986;208():171-5.
1985: Fuad N Ziyadeh; E Kelepouris; Mortimer M Civan; Z S Agus
cAMP- and beta-adrenergic-stimulated chloride-dependent Ca2+ secretion in frog skin.
The American journal of physiology 1985;249(5 Pt 2):F713-22.