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Vincent Lee

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
50
Kim, Kwang-Jin
13
Gukasyan, Hovhannes
10
Hosoya, KI
8
Haworth, Ian
8
Kulkarni, Ashutosh
8
Kannan, Ram
7
Horibe, Y
7
Basu, SK
7
Kompella, Uday
6
Okamoto, Curtis
6
Ann, David
6
Crandall, Edward
5
Shiue, Michael
5
Lehr, Claus-Michael
5
Wu, Sharon

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Publications

TOP 3
Wang Zhi-Jun; Wo Siu-Kwan; Wang Ling; Lau Clara B S; Lee Vincent H L; Chow Moses S S; Zuo Zhong
Simultaneous quantification of active components in the herbs and products of Si-Wu-Tang by high performance liquid chromatography-mass spectrometry.
Lee Vincent H L
Shaping the transformation of pharmaceutical science.
Chen Mei-Ling; Lee Vincent H L
Equivalence-by-design: targeting in vivo drug delivery profile.

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All Publications

2009: Wang Zhi-Jun; Wo Siu-Kwan; Wang Ling; Lau Clara B S; Lee Vincent H L; Chow Moses S S; Zuo Zhong
Simultaneous quantification of active components in the herbs and products of Si-Wu-Tang by high performance liquid chromatography-mass spectrometry.
Journal of pharmaceutical and biomedical analysis 2009;50(2):232-44.
2008: Lee Vincent H L
Shaping the transformation of pharmaceutical science.
Pharmaceutical research 2008;25(12):2707-12.
2008: Chen Mei-Ling; Lee Vincent H L
Equivalence-by-design: targeting in vivo drug delivery profile.
Pharmaceutical research 2008;25(12):2723-30.
2008: Patel Leena N; Uchiyama Tomomi; Kim Kwang-Jin; Borok Zea; Crandall Edward D; Shen Wei-Chiang; Lee Vincent H L
Molecular and functional expression of multidrug resistance-associated protein-1 in primary cultured rat alveolar epithelial cells.
Journal of pharmaceutical sciences 2008;97(6):2340-9.
2008: Uchiyama Tomomi; Fujita Takuya; Gukasyan Hovhannes J; Kim Kwang-Jin; Borok Zea; Crandall Edward D; Lee Vincent H L
Functional characterization and cloning of amino acid transporter B(0,+) (ATB(0,+)) in primary cultured rat pneumocytes.
Journal of cellular physiology 2008;214(3):645-54.
2008: Lee Vincent H L
A personal tribute to Joseph R. Robinson: an inspiration for all generations.
Pharmaceutical research 2008;25(1):1-2.
2007: Gukasyan Hovhannes J; Kim Kwang-Jin; Lee Vincent H L; Kannan Ram
Glutathione and its transporters in ocular surface defense.
The ocular surface 2007;5(4):269-79.
2007: Yang Johnny J; Ann David K; Kannan Ram; Lee Vincent H L
Multidrug resistance protein 1 (MRP1) in rabbit conjunctival epithelial cells: its effect on drug efflux and its regulation by adenoviral infection.
Pharmaceutical research 2007;24(8):1490-500.
2007: Links Jennifer L S; Kulkarni Ashutosh A; Davies Daryl L; Lee Vincent H L; Haworth Ian S
Cysteine scanning of transmembrane domain three of the human dipeptide transporter: implications for substrate transport.
Journal of drug targeting 2007;15(3):218-25.
2007: Kulkarni Ashutosh A; Davies Daryl L; Links Jennifer S; Patel Leena N; Lee Vincent H L; Haworth Ian S
A charge pair interaction between Arg282 in transmembrane segment 7 and Asp341 in transmembrane segment 8 of hPepT1.
Pharmaceutical research 2007;24(1):66-72.
2006: Gukasyan Hovhannes J; Lee Vincent H L; Simityan Hagop; Kim Kwang-Jin; Kannan Ram
Thermodynamic stoichiometry of Na+-coupled glutathione transport.
Canadian journal of physiology and pharmacology 2006;84(11):1223-7.
2006: Zhang Ning; Kannan Ram; Okamoto Curtis T; Ryan Stephen J; Lee Vincent H L; Hinton David R
Characterization of brimonidine transport in retinal pigment epithelium.
Investigative ophthalmology & visual science 2006;47(1):287-94.
2005: Lee Vincent H L
Drug delivery systems for treating orphan retinal diseases.
Retina (Philadelphia, Pa.) 2005;25(8 Suppl):S44-S45.
2005: Attar Mayssa; Ling Kah-Hiing John; Tang-Liu Diane D-S; Neamati Nouri; Lee Vincent H L
Cytochrome P450 3A expression and activity in the rabbit lacrimal gland: glucocorticoid modulation and the impact on androgen metabolism.
Investigative ophthalmology & visual science 2005;46(12):4697-706.
2005: Wu Sharon K; Mathias Neil R; Kim Kwang-Jin; Lee Vincent H L
Functional and pharmacological mechanisms of nucleoside transport across the basolateral membrane of rabbit tracheal epithelial cells.
Life sciences 2005;78(3):310-20.
2005: Lee Vincent H L
Steve Carney talks to Vincent Lee on the pharma industry, the FDA and public education with respect to drugs and their development.
Drug discovery today 2005;10(21):1411-4.
2005: Wu Sharon K; Ann David K; Kim Kwang-Jin; Lee Vincent H L
Fine tuning of rabbit equilibrative nucleoside transporter activity by an alternatively spliced variant.
Journal of drug targeting 2005;13(8-9):521-33.
2005: Mathias Neil R; Wu Sharon K; Kim Kwang-Jin; Lee Vincent H L
Nucleoside transport in primary cultured rabbit tracheal epithelial cells.
Journal of drug targeting 2005;13(8-9):509-19.
2005: Lee Vincent H L
Editorial: a tribute to Professor A.T. Florence for his life-time research achievements.
Journal of drug targeting 2005;13(8-9):447-8.
2005: Hosoya Ken-ichi; Lee Vincent H L; Kim Kwang-Jin
Roles of the conjunctiva in ocular drug delivery: a review of conjunctival transport mechanisms and their regulation.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2005;60(2):227-40.
2005: Becker Ulrich; Ehrhardt Carsten; Schaefer Ulrich F; Gukasyan Hovhannes J; Kim Kwang-Jin; Lee Vincent H L; Lehr Claus-Michael
Tissue distribution of moxaverine-hydrochloride in the rabbit eye and plasma.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2005;21(3):210-6.
2005: Chang-Lin Joan-En; Kim Kwang-Jin; Lee Vincent H L
Characterization of active ion transport across primary rabbit corneal epithelial cell layers (RCrECL) cultured at an air-interface.
Experimental eye research 2005;80(6):827-36.
2004: Chu Chun; Okamoto Curtis T; Hamm-Alvarez Sarah F; Lee Vincent H L
Stable transfection of MDCK cells with epitope-tagged human PepT1.
Pharmaceutical research 2004;21(11):1970-3.
2004: Kim Kwang-Jin; Fandy Tamer E; Lee Vincent H L; Ann David K; Borok Zea; Crandall Edward D
Net absorption of IgG via FcRn-mediated transcytosis across rat alveolar epithelial cell monolayers.
American journal of physiology. Lung cellular and molecular physiology 2004;287(3):L616-22.
2004: Qaddoumi Mohamed; Lee Vincent H L
Lectins as endocytic ligands: an assessment of lectin binding and uptake to rabbit conjunctival epithelial cells.
Pharmaceutical research 2004;21(7):1160-6.
2004: Kannan Ram; Gukasyan Hovhannes J; Zhang Wenzheng; Trousdale Melvin D; Kim Kwang-Jin; Lee Vincent H L
Impairment of conjunctival glutathione secretion and ion transport by oxidative stress in an adenovirus type 5 ocular infection model of pigmented rabbits.
Free radical biology & medicine 2004;37(2):229-38.
2004: Polli James E; Yu Lawrence X; Cook Jack A; Amidon Gordon L; Borchardt Ronald T; Burnside Beth A; Burton Philip S; Chen Mei-Ling; Conner Dale P; Faustino Patrick J; Hawi Amale A; Hussain Ajaz S; Joshi Hemant N; Kwei Gloria; Lee Vincent H L; Lesko Lawrence J; Lipper Robert A; Loper Alice E; Nerurkar Shriniwas G; Polli Joseph W; Sanvordeker Dilip R; Taneja Rajneesh; Uppoor Ramana S; Vattikonda Chandra S; Wilding Ian; Zhang Guohua
Summary workshop report: biopharmaceutics classification system--implementation challenges and extension opportunities.
Journal of pharmaceutical sciences 2004;93(6):1375-81.
2004: Qaddoumi Mohamed G; Ueda Hideo; Yang Johnny; Davda Jasmine; Labhasetwar Vinod; Lee Vincent H L
The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers.
Pharmaceutical research 2004;21(4):641-8.
2004: Lee Vincent H L
Advanced Drug Delivery Reviews: cornerstone in the stimulation and dissemination of innovative drug delivery research.
Advanced drug delivery reviews 2004;56(1):1-2.
2003: Uchiyama Tomomi; Kulkarni Ashutosh A; Davies Daryl L; Lee Vincent H L
Biophysical evidence for His57 as a proton-binding site in the mammalian intestinal transporter hPepT1.
Pharmaceutical research 2003;20(12):1911-6.
2003: Kulkarni Ashutosh A; Haworth Ian S; Uchiyama Tomomi; Lee Vincent H L
Analysis of transmembrane segment 7 of the dipeptide transporter hPepT1 by cysteine-scanning mutagenesis.
The Journal of biological chemistry 2003;278(51):51833-40.
2003: Qaddoumi Mohamed G; Gukasyan Hovhannes J; Davda Jasmine; Labhasetwar Vinod; Kim Kwang-Jin; Lee Vincent H L
Clathrin and caveolin-1 expression in primary pigmented rabbit conjunctival epithelial cells: role in PLGA nanoparticle endocytosis.
Molecular vision 2003;9():559-68.
2003: Gukasyan Hovhannes J; Kim Kwang-Jin; Kannan Ram; Farley Robert A; Lee Vincent H L
Specialized protective role of mucosal glutathione in pigmented rabbit conjunctiva.
Investigative ophthalmology & visual science 2003;44(10):4427-38.
2003: Attar Mayssa; Lee Vincent H L
Pharmacogenomic considerations in drug delivery.
Pharmacogenomics 2003;4(4):443-61.
2003: Kulkarni Ashutosh A; Haworth Ian S; Lee Vincent H L
Transmembrane segment 5 of the dipeptide transporter hPepT1 forms a part of the substrate translocation pathway.
Biochemical and biophysical research communications 2003;306(1):177-85.
2003: Kulkarni Ashutosh A; Trousdale Melvin D; Stevenson Douglas; Gukasyan Hovhannes J; Shiue Michael H I; Kim Kwang-Jin; Read Russell W; Lee Vincent H L
Nucleotide-induced restoration of conjunctival chloride and fluid secretion in adenovirus type 5-infected pigmented rabbit eyes.
The Journal of pharmacology and experimental therapeutics 2003;305(3):1206-11.
2003: Gukasyan Hovhannes J; Kannan Ram; Lee Vincent H L; Kim Kwang-Jin
Regulation of L-cystine transport and intracellular GSH level by a nitric oxide donor in primary cultured rabbit conjunctival epithelial cell layers.
Investigative ophthalmology & visual science 2003;44(3):1202-10.
2003: Kim Kwang-Jin; Matsukawa Yasuhisa; Yamahara Hiroshi; Kalra Vijay K; Lee Vincent H L; Crandall Edward D
Absorption of intact albumin across rat alveolar epithelial cell monolayers.
American journal of physiology. Lung cellular and molecular physiology 2003;284(3):L458-65.
2002: Scholz Martina; Lin Joan-En Chang; Lee Vincent H L; Keipert Sigrid
Pilocarpine permeability across ocular tissues and cell cultures: influence of formulation parameters.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2002;18(5):455-68.
2002: Yu Lawrence X; Amidon Gordon L; Polli James E; Zhao Hong; Mehta Mehul U; Conner Dale P; Shah Vinod P; Lesko Lawrence J; Chen Mei-Ling; Lee Vincent H L; Hussain Ajaz S
Biopharmaceutics classification system: the scientific basis for biowaiver extensions.
Pharmaceutical research 2002;19(7):921-5.
2002: Shiue Michael H I; Gukasyan Hovhannes J; Kim Kwang-Jin; Loo Donald D F; Lee Vincent H L
Characterization of cyclic AMP-regulated chloride conductance in the pigmented rabbit conjunctival epithelial cells.
Canadian journal of physiology and pharmacology 2002;80(6):533-40.
2002: Gukasyan Hovhannes J; Lee Vincent H L; Kim Kwang-Jin; Kannan Ram
Net glutathione secretion across primary cultured rabbit conjunctival epithelial cell layers.
Investigative ophthalmology & visual science 2002;43(4):1154-61.
2002: Gukasyan Hovhannes J; Yerxa Benjamin R; Pendergast William; Lee Vincent H L
Metabolism and transport of purinergic receptor agonists in rabbit conjunctival epithelial cells.
Advances in experimental medicine and biology 2002;506(Pt A):255-9.
2002: Lee Vincent H L; Kulkarni Ashutosh A; Shiue Michael H I
Nucleoside and nucleotide stimulation of fluid secretion in the pigmented rabbit conjunctiva.
Advances in experimental medicine and biology 2002;506(Pt A):249-54.
2002: Shen Jie; Lee Vincent H L
Application of epithelial cell culture in drug transport in the respiratory tract.
Methods in molecular biology (Clifton, N.J.) 2002;188():217-32.
2001: Lee V H; Sporty J L; Fandy T E
Pharmacogenomics of drug transporters: the next drug delivery challenge.
Advanced drug delivery reviews 2001;50 Suppl 1():S33-40.
2001: Kompella U B; Lee V H
Delivery systems for penetration enhancement of peptide and protein drugs: design considerations.
Advanced drug delivery reviews 2001;46(1-3):211-45.
2000: Lee V H
Membrane transporters.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2000;11 Suppl 2():S41-50.
2000: Chang J E; Basu S K; Lee V H
Air-interface condition promotes the formation of tight corneal epithelial cell layers for drug transport studies.
Pharmaceutical research 2000;17(6):670-6.
2000: Yang J J; Kim K J; Lee V H
Role of P-glycoprotein in restricting propranolol transport in cultured rabbit conjunctival epithelial cell layers.
Pharmaceutical research 2000;17(5):533-8.
2000: Ueda H; Horibe Y; Kim K J; Lee V H
Functional characterization of organic cation drug transport in the pigmented rabbit conjunctiva.
Investigative ophthalmology & visual science 2000;41(3):870-6.
2000: Yang J J; Ueda H; Kim K; Lee V H
Meeting future challenges in topical ocular drug delivery: development of an air-interfaced primary culture of rabbit conjunctival epithelial cells on a permeable support for drug transport studies.
Journal of controlled release : official journal of the Controlled Release Society 2000;65(1-2):1-11.
2000: Shiue M H; Kulkarni A A; Gukasyan H J; Swisher J B; Kim K J; Lee V H
Pharmacological modulation of fluid secretion in the pigmented rabbit conjunctiva.
Life sciences 2000;66(7):PL105-11.
2000: Matsukawa Y; Yamahara H; Yamashita F; Lee V H; Crandall E D; Kim K J
Rates of protein transport across rat alveolar epithelial cell monolayers.
Journal of drug targeting 2000;7(5):335-42.
1999: Lee V H; Chu C; Mahlin E D; Basu S K; Ann D K; Bolger M B; Haworth I S; Yeung A K; Wu S K; Hamm-Alvarez S; Okamoto C T
Biopharmaceutics of transmucosal peptide and protein drug administration: role of transport mechanisms with a focus on the involvement of PepT1.
Journal of controlled release : official journal of the Controlled Release Society 1999;62(1-2):129-40.
1999: Hosoya K; Ueda H; Kim K J; Lee V H
Nucleotide stimulation of Cl(-) secretion in the pigmented rabbit conjunctiva.
The Journal of pharmacology and experimental therapeutics 1999;291(1):53-9.
1999: Shen J; Elbert K J; Yamashita F; Lehr C M; Kim K J; Lee V H
Organic cation transport in rabbit alveolar epithelial cell monolayers.
Pharmaceutical research 1999;16(8):1280-7.
1999: Elbert K J; Schäfer U F; Schäfers H J; Kim K J; Lee V H; Lehr C M
Monolayers of human alveolar epithelial cells in primary culture for pulmonary absorption and transport studies.
Pharmaceutical research 1999;16(5):601-8.
1998: Bolger M B; Haworth I S; Yeung A K; Ann D; von Grafenstein H; Hamm-Alvarez S; Okamoto C T; Kim K J; Basu S K; Wu S; Lee V H
Structure, function, and molecular modeling approaches to the study of the intestinal dipeptide transporter PepT1.
Journal of pharmaceutical sciences 1998;87(11):1286-91.
1998: Basu S K; Haworth I S; Bolger M B; Lee V H
Proton-driven dipeptide uptake in primary cultured rabbit conjunctival epithelial cells.
Investigative ophthalmology & visual science 1998;39(12):2365-73.
1998: Yeung A K; Basu S K; Wu S K; Chu C; Okamoto C T; Hamm-Alvarez S F; von Grafenstein H; Shen W C; Kim K J; Bolger M B; Haworth I S; Ann D K; Lee V H
Molecular identification of a role for tyrosine 167 in the function of the human intestinal proton- coupled dipeptide transporter (hPepT1).
Biochemical and biophysical research communications 1998;250(1):103-7.
1998: Yamashita F; Kim K J; Lee V H
Dipeptide uptake and transport characteristics in rabbit tracheal epithelial cell layers cultured at an air interface.
Pharmaceutical research 1998;15(7):979-83.
1998: Horibe Y; Hosoya K; Kim K J; Lee V H
Carrier-mediated transport of monocarboxylate drugs in the pigmented rabbit conjunctiva.
Investigative ophthalmology & visual science 1998;39(8):1436-43.
1998: Saha P; Yang J J; Lee V H
Existence of a p-glycoprotein drug efflux pump in cultured rabbit conjunctival epithelial cells.
Investigative ophthalmology & visual science 1998;39(7):1221-6.
1998: Hosoya K I; Horibe Y; Kim K J; Lee V H
Carrier-mediated transport of NG-nitro-L-arginine, a nitric oxide synthase inhibitor, in the pigmented rabbit conjunctiva.
The Journal of pharmacology and experimental therapeutics 1998;285(1):223-7.
1998: Shiue M H; Kim K J; Lee V H
Modulation of chloride secretion across the pigmented rabbit conjunctiva.
Experimental eye research 1998;66(3):275-82.
1998: Basu S K; Shen J; Elbert K J; Okamoto C T; Lee V H; von Grafenstein H
Development and utility of anti-PepT1 anti-peptide polyclonal antibodies.
Pharmaceutical research 1998;15(2):338-42.
1998: Hosoya K; Horibe Y; Kim K J; Lee V H
Nucleoside transport mechanisms in the pigmented rabbit conjunctiva.
Investigative ophthalmology & visual science 1998;39(2):372-7.
1998: Sun L; Basu S K; Kim K J; Lee V H
Arginine vasopressin transport and metabolism in the pigmented rabbit conjunctiva.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1998;6(1):47-52.
1997: Tsai Y J; Rottero A; Chow D D; Hwang K J; Lee V H; Zhu G; Chan K K
Synthesis and purification of NB1-palmitoyl insulin.
Journal of pharmaceutical sciences 1997;86(11):1264-8.
1997: Hosoya K; Horibe Y; Kim K J; Lee V H
Na(+)-dependent L-arginine transport in the pigmented rabbit conjunctiva.
Experimental eye research 1997;65(4):547-53.
1997: Horibe Y; Hosoya K; Kim K J; Lee V H
Kinetic evidence for Na(+)-glucose co-transport in the pigmented rabbit conjunctiva.
Current eye research 1997;16(10):1050-5.
1997: Horibe Y; Hosoya K; Kim K J; Ogiso T; Lee V H
Polar solute transport across the pigmented rabbit conjunctiva: size dependence and the influence of 8-bromo cyclic adenosine monophosphate.
Pharmaceutical research 1997;14(9):1246-51.
1997: Hosoya K; Lee V H
Cidofovir transport in the pigmented rabbit conjunctiva.
Current eye research 1997;16(7):693-7.
1997: Matsukawa Y; Lee V H; Crandall E D; Kim K J
Size-dependent dextran transport across rat alveolar epithelial cell monolayers.
Journal of pharmaceutical sciences 1997;86(3):305-9.
1997: Yamashita F; Kim K J; Lee V H
Gly-L-Phe transport and metabolism across primary cultured rabbit tracheal epithelial cell monolayers.
Pharmaceutical research 1997;14(2):238-40.
1996: Saha P; Uchiyama T; Kim K J; Lee V H
Permeability characteristics of primary cultured rabbit conjunctival epithelial cells to low molecular weight drugs.
Current eye research 1996;15(12):1170-4.
1996: Saha P; Kim K J; Lee V H
A primary culture model of rabbit conjunctival epithelial cells exhibiting tight barrier properties.
Current eye research 1996;15(12):1163-9.
1996: Matsukawa Y; Yamahara H; Lee V H; Crandall E D; Kim K J
Horseradish peroxidase transport across rat alveolar epithelial cell monolayers.
Pharmaceutical research 1996;13(9):1331-5.
1996: Hosoya K I; Kim K J; Lee V H
Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers.
Pharmaceutical research 1996;13(6):885-90.
1996: Hosoya K; Kompella U B; Kim K J; Lee V H
Contribution of Na(+)-glucose cotransport to the short-circuit current in the pigmented rabbit conjunctiva.
Current eye research 1996;15(4):447-51.
1996: Mathias N R; Kim K J; Lee V H
Targeted drug delivery to the respiratory tract: solute permeability of air-interface cultured rabbit tracheal epithelial cell monolayers.
Journal of drug targeting 1996;4(2):79-86.
1996: Kompella U B; Kim K J; Shiue M H; Lee V H
Cyclic AMP modulation of active ion transport in the pigmented rabbit conjunctiva.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 1996;12(3):281-7.
1996: Lee V H; Yamahara H; Gurny R; Sintzel M B; Martenet M; Gex-Fabry M; Balant L; Ohdo S; Podder S K
Basis for dosing time-dependent changes in the ocular and systemic absorption of topically applied timolol.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 1996;12(2):103-13.
1995: Mathias N R; Kim K J; Robison T W; Lee V H
Development and characterization of rabbit tracheal epithelial cell monolayer models for drug transport studies.
Pharmaceutical research 1995;12(10):1499-505.
1995: Narawane M A; Lee V H
IGF-I and EGF receptors in the pigmented rabbit bulbar conjunctiva.
Current eye research 1995;14(10):905-10.
1995: Yen W C; Lee V H
Role of Na+ in the asymmetric paracellular transport of 4-phenylazobenzyloxycarbonyl-L-Pro-L-Leu-Gly-L-Pro-D-Arg across rabbit colonic segments and Caco-2 cell monolayers.
The Journal of pharmacology and experimental therapeutics 1995;275(1):114-9.
1995: Kompella U B; Kim K J; Shiue M H; Lee V H
Possible existence of Na(+)-coupled amino acid transport in the pigmented rabbit conjunctiva.
Life sciences 1995;57(15):1427-31.
1994: Yamahara H; Morimoto K; Lee V H; Kim K J
Effects of protease inhibitors on vasopressin transport across rat alveolar epithelial cell monolayers.
Pharmaceutical research 1994;11(11):1617-22.
1994: Lehr C M; Lee Y H; Lee V H
Improved ocular penetration of gentamicin by mucoadhesive polymer polycarbophil in the pigmented rabbit.
Investigative ophthalmology & visual science 1994;35(6):2809-14.
1994: Morimoto K; Yamahara H; Lee V H; Kim K J
Transport of thyrotropin-releasing hormone across rat alveolar epithelial cell monolayers.
Life sciences 1994;54(26):2083-92.
1994: Lee V H; Li S Y; Sasaki H; Saettone M F; Chetoni P
Influence of drug release rate on systemic timolol absorption from polymeric ocular inserts in the pigmented rabbit.
Journal of ocular pharmacology 1994;10(2):421-9.
1993: Lehr C M; Lee V H
Binding and transport of some bioadhesive plant lectins across Caco-2 cell monolayers.
Pharmaceutical research 1993;10(12):1796-9.
1993: Kompella U B; Kim K J; Lee V H
Active chloride transport in the pigmented rabbit conjunctiva.
Current eye research 1993;12(12):1041-8.
1993: Morimoto K; Yamahara H; Lee V H; Kim K J
Dipeptide transport across rat alveolar epithelial cell monolayers.
Pharmaceutical research 1993;10(11):1668-74.
1993: Lee Y H; Kompella U B; Lee V H
Systemic absorption pathways of topically applied beta adrenergic antagonists in the pigmented rabbit.
Experimental eye research 1993;57(3):341-9.
1993: Ma W; Hwang K J; Lee V H
Use of the gamma-ray perturbed angular correlation (PAC) technique for monitoring liposomal phospholipid bilayer integrity.
Pharmaceutical research 1993;10(2):252-7.
1993: Ma W; Hwang K J; Lee V H
A fluorescence quenching method for estimating chelating groups in chelate-conjugated macromolecules.
Pharmaceutical research 1993;10(2):204-7.
1993: Lee Y H; Lee V H
Formulation influence on ocular and systemic absorption of topically applied atenolol in the pigmented rabbit.
Journal of ocular pharmacology 1993;9(1):47-58.
1993: Narawane M; Podder S K; Bundgaard H; Lee V H
Segmental differences in drug permeability, esterase activity and ketone reductase activity in the albino rabbit intestine.
Journal of drug targeting 1993;1(1):29-39.
1992: Yamamoto A; Hayakawa E; Kato Y; Nishiura A; Lee V H
A mechanistic study on enhancement of rectal permeability to insulin in the albino rabbit.
The Journal of pharmacology and experimental therapeutics 1992;263(1):25-31.
1992: Hayakawa E; Chien D S; Inagaki K; Yamamoto A; Wang W; Lee V H
Conjunctival penetration of insulin and peptide drugs in the albino rabbit.
Pharmaceutical research 1992;9(6):769-75.
1992: Podder S K; Moy K C; Lee V H
Improving the safety of topically applied timolol in the pigmented rabbit through manipulation of formulation composition.
Experimental eye research 1992;54(5):747-57.
1992: Ashton P; Clark D S; Lee V H
A mechanistic study on the enhancement of corneal penetration of phenylephrine by flurbiprofen in the rabbit.
Current eye research 1992;11(1):85-90.
1992: Chen F; Liu Y; Lu J; Hwang K J; Lee V H
A sensitive fluorometric assay for reducing sugars.
Life sciences 1992;50(9):651-9.
1992: Ohdo S; Zhu J; Lee V H
Light-dark variations in ocular timolol concentrations following topical solution instillation in the pigmented rabbit.
Life sciences 1992;51(26):2025-31.
1991: Ashton P; Wang W; Lee V H
Location of penetration and metabolic barriers to levobunolol in the corneal epithelium of the pigmented rabbit.
The Journal of pharmacology and experimental therapeutics 1991;259(2):719-24.
1991: Lee V H; Luo A M; Li S Y; Podder S K; Chang J S; Ohdo S; Grass G M
Pharmacokinetic basis for nonadditivity of intraocular pressure lowering in timolol combinations.
Investigative ophthalmology & visual science 1991;32(11):2948-57.
1991: Ashton P; Podder S K; Lee V H
Formulation influence on conjunctival penetration of four beta blockers in the pigmented rabbit: a comparison with corneal penetration.
Pharmaceutical research 1991;8(9):1166-74.
1991: Chien D S; Sasaki H; Bundgaard H; Buur A; Lee V H
Role of enzymatic lability in the corneal and conjunctival penetration of timolol ester prodrugs in the pigmented rabbit.
Pharmaceutical research 1991;8(6):728-33.
1991: Wang W; Sasaki H; Chien D S; Lee V H
Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: a comparison with corneal penetration.
Current eye research 1991;10(6):571-9.
1991: Luo A M; Sasaki H; Lee V H
Ocular drug interactions involving topically applied timolol in the pigmented rabbit.
Current eye research 1991;10(3):231-40.
1991: Wang W; Bundgaard H; Buur A; Lee V H
Corneal penetration of 5-fluorouracil and its improvement by prodrug derivatization in the albino rabbit: implication in glaucoma filtration surgery.
Current eye research 1991;10(1):87-97.
1991: Lee V H; Yamamoto A; Kompella U B
Mucosal penetration enhancers for facilitation of peptide and protein drug absorption.
Critical reviews in therapeutic drug carrier systems 1991;8(2):91-192.
1990: Ashton P; Diepold R; Platzer A; Lee V H
The effect of chlorhexidine acetate on the corneal penetration of sorbitol from an arnolol formulation in the albino rabbit.
Journal of ocular pharmacology 1990;6(1):37-42.
1990: Lee V H
New directions in the optimization of ocular drug delivery.
Journal of ocular pharmacology 1990;6(2):157-64.
1990: Shih R L; Lee V H
Rate limiting barrier to the penetration of ocular hypotensive beta blockers across the corneal epithelium in the pigmented rabbit.
Journal of ocular pharmacology 1990;6(4):329-36.
1990: Yamamoto A; Hayakawa E; Lee V H
Insulin and proinsulin proteolysis in mucosal homogenates of the albino rabbit: implications in peptide delivery from nonoral routes.
Life sciences 1990;47(26):2465-74.
1989: Yamamoto A; Luo A M; Dodda-Kashi S; Lee V H
The ocular route for systemic insulin delivery in the albino rabbit.
The Journal of pharmacology and experimental therapeutics 1989;249(1):249-55.
1989: Hayakawa E; Yamamoto A; Shoji Y; Lee V H
Effect of sodium glycocholate and polyoxyethylene-9-lauryl ether on the hydrolysis of varying concentrations of insulin in the nasal homogenates of the albino rabbit.
Life sciences 1989;45(2):167-74.
1988: Stratford R E; Carson L W; Dodda-Kashi S; Lee V H
Systemic absorption of ocularly administered enkephalinamide and inulin in the albino rabbit: extent, pathways, and vehicle effects.
Journal of pharmaceutical sciences 1988;77(10):838-42.
1988: Lee V H; Chien D S; Sasaki H
Ocular ketone reductase distribution and its role in the metabolism of ocularly applied levobunolol in the pigmented rabbit.
The Journal of pharmacology and experimental therapeutics 1988;246(3):871-8.
1988: Chang S C; Bundgaard H; Buur A; Lee V H
Low dose O-butyryl timolol improves the therapeutic index of timolol in the pigmented rabbit.
Investigative ophthalmology & visual science 1988;29(4):626-9.
1988: Chang S C; Chien D S; Bundgaard H; Lee V H
Relative effectiveness of prodrug and viscous solution approaches in maximizing the ratio of ocular to systemic absorption of topically applied timolol.
Experimental eye research 1988;46(1):59-69.
1988: Bundgaard H; Buur A; Lee V H
Timolol prodrugs: preparation and hydrolysis kinetics of N-benzoyl carbamate esters of timolol and related compounds.
Acta pharmaceutica Suecica 1988;25(6):293-306.
1988: Chien D S; Bundgaard H; Lee V H
Influence of corneal epithelial integrity on the penetration of timolol prodrugs.
Journal of ocular pharmacology 1988;4(2):137-46.
1988: Lee V H
Enzymatic barriers to peptide and protein absorption.
Critical reviews in therapeutic drug carrier systems 1988;5(2):69-97.
1987: Chang S C; Bundgaard H; Buur A; Lee V H
Improved corneal penetration of timolol by prodrugs as a means to reduce systemic drug load.
Investigative ophthalmology & visual science 1987;28(3):487-91.
1987: Chang S C; Lee V H
Nasal and conjunctival contributions to the systemic absorption of topical timolol in the pigmented rabbit: implications in the design of strategies to maximize the ratio of ocular to systemic absorption.
Journal of ocular pharmacology 1987;3(2):159-69.
1986: Lee V H; Carson L W; Kashi S D; Stratford R E
Metabolic and permeation barriers to the ocular absorption of topically applied enkephalins in albino rabbits.
Journal of ocular pharmacology 1986;2(4):345-52.
1986: Lee V H; Carson L W
Ocular disposition of inulin from single & multiple doses of positively charged multilamellar liposomes: evidence for alterations in tear dynamics and ocular surface characteristics.
Journal of ocular pharmacology 1986;2(4):353-64.
1986: Lee V H; Robinson J R
Topical ocular drug delivery: recent developments and future challenges.
Journal of ocular pharmacology 1986;2(1):67-108.
1985: Lee V H; Carson L W
Possible mechanisms for the retention of topically applied vitamin A (retinol) in the albino rabbit eye.
Journal of ocular pharmacology 1985;1(3):297-308.
1985: Lee V H; Smith R E
Effect of substrate concentration, product concentration, and peptides on the in vitro hydrolysis of model ester prodrugs by corneal esterases.
Journal of ocular pharmacology 1985;1(3):269-78.

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